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Mansory, Mazin. "The Significance of Non-traditional and Alternative Assessment in English Language Teaching: Evidence From Literature." International Journal of Linguistics 12, no. 5 (2020): 210. http://dx.doi.org/10.5296/ijl.v12i5.17782.
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Assessment is an integral part of teaching and learning in educational organizations that requires teachers to prepare tests in order to evaluate their learners’ performance. In language teaching contexts, traditional assessment often evaluates learners’ knowledge of previously learned language items. It is a mandatory process that determines the progress of language learners and the effectiveness of teaching/learning materials. This theoretical article reviews the literature on the notion of traditional assessment or static assessment which has certain shortcomings. Owing to the various drawbacks of static assessment, the review of related literature on the topic highlights and proposes alternative assessment methods, such as authentic assessment, dynamic assessment, peer assessment, and self-assessment. In contrast to traditional assessment, these different forms of alternative assessment share a common purpose that is to provide language learners with an opportunity to reflect on their strengths and weaknesses and set their future learning goals. The most common of the assessment methods that encourage learners' reflection were peer assessment and self-assessment which involve learners to assess their own progress as well as engage with peers in classrooms to give each other feedback on their language learning tasks assigned by teachers. The studies reviewed in this article illustrate that alternative assessment methods in the form of peer and self-assessment have a positive influence on the language learners' performance and their learning outcomes.
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Chong, Mike R., Lori Goff, and Kimberly Dej. "12. Undergraduate Essay Writing: Online and Face-to-Face Peer Reviews." Collected Essays on Learning and Teaching 5 (June 19, 2012): 69. http://dx.doi.org/10.22329/celt.v5i0.3423.
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We implemented two different approaches of using peer review to support undergraduate essay assignments for students taking large second-year courses in life sciences and biology: a web-based online peer review (OPR) approach and a more traditional face-to-face peer review (FPR) approach that was conducted in tutorial settings. The essays consisted of a review of current literature to discuss the molecular involvement of cancer development or stem-cell growth. Following implementation of the peer reviews, we conducted a preliminary analysis of the pros and cons of using the two methods. Student and instructor feedback suggested that the activity of peer review was generally perceived as valuable regardless of which approach was used. OPR was convenient and saved time and resources relative to FPR, but the technical drawbacks using the OPR approach made it challenging for some students to use. A subsequent investigation using alternative OPR programs that offer additional functionality is planned.
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Lin, Li, Rui Zhi Wen, Bao Feng Zhou, and Da Cheng Shi. "Study on Strong Motion Records Database and Selection Methods." Applied Mechanics and Materials 256-259 (December 2012): 2117–21. http://dx.doi.org/10.4028/www.scientific.net/amm.256-259.2117.
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In this paper, PEER Ground Motion Databases (PGMD) at the Pacific Earthquake Engineering Research Center (PEER) was updated by 314 sets of ground motion records of great earthquakes in recent years, which expanded the application of this database. This paper reviews alternative selection methods for strong ground motion records. The expanded database could make the different selection and scaling of strong motion records in great earthquakes, and the conditional mean spectrum (CMS) method could be applied for the strong motion records selection in structural spectrum analysis.
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Stokes, William S., Leonard M. Schechtman, and Richard N. Hill. "The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): A Review of the ICCVAM Test Method Evaluation Process and Current International Collaborations with the European Centre for the Validation of Alternative Methods (ECVAM)." Alternatives to Laboratory Animals 30, no. 2_suppl (2002): 23–32. http://dx.doi.org/10.1177/026119290203002s04.
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Over the last decade, national authorities in the USA and Europe have launched initiatives to validate new and improved toxicological test methods. In the USA, the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), and its supporting National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), were established by the Federal Government to work with test developers and Federal agencies to facilitate the validation, review, and adoption of new scientifically sound test methods, including alternatives that can reduce, refine, and replace animal use. In Europe, the European Centre for the Validation of Alternative Methods (ECVAM) was established to conduct validation studies on alternative test methods. Despite differences in organisational structure and processes, both organisations seek to achieve the adoption and use of alternative test methods. Accordingly, both have adopted similar validation and regulatory acceptance criteria. Collaborations and processes have also evolved to facilitate the international adoption of new test methods recommended by ECVAM and ICCVAM. These collaborations involve the sharing of expertise and data for test-method workshops and independent scientific peer reviews, and the adoption of processes to expedite the consideration of test methods already reviewed by the other organisation. More recently, NICEATM and ECVAM initiated a joint international validation study on in vitro methods for assessing acute systemic toxicity. These collaborations are expected to contribute to accelerated international adoption of harmonised new test methods that will support improved public health and provide for reduced and more-humane use of laboratory animals.
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Kirkham, Jamie, and David Moher. "Who and why do researchers opt to publish in post-publication peer review platforms? - findings from a review and survey of F1000 Research." F1000Research 7 (June 27, 2018): 920. http://dx.doi.org/10.12688/f1000research.15436.1.
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Background: Preprint servers and alternative publication platforms enable authors to accelerate the dissemination of their research. In recent years there has been an exponential increase in the use of such servers and platforms in the biomedical sciences, although little is known about who, why and what experiences researchers have with publishing on such platforms. In this article we explore one of these alternative publication platforms, F1000 Research, which offers immediate publication followed by post-publication peer review. Methods: From an unselected cohort of articles published between 13th July 2012 and 30th November 2017 in F1000 Research, we provided a summary of who and what was published on this platform and calculated the percentage of published articles that had been indexed on a bibliographic database (PubMed) following successful post-publication peer review. We also surveyed corresponding authors to further understand the rationale and experiences of those that have published using this platform. Results: A total of 1865 articles had been published in the study cohort period, of which 80% (n=1488) had successfully undergone peer review and were indexed on PubMed within a minimum period of six months since first publication. Nearly three-quarters of articles passed the peer review process with their initial submission. Survey responses were received from 296 corresponding authors. Open access, open peer review and the speed of publication were the three main reasons why authors opted to publish with F1000 Research. Conclusions: Many who published with F1000 Research had a positive experience and indicated that they would publish again with this same platform in the future. Nevertheless, there remained some concerns about the peer review process and the quality of the articles that were published.
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Anonymous. "Peer review report 1 on “Preserving the variance in imputed eddy-covariance measurements: alternative methods for defensible gap filling”." Agricultural and Forest Meteorology 217 (January 2016): 503. http://dx.doi.org/10.1016/j.agrformet.2016.11.253.
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Fagerjord, Anders. "Humanist Evaluation Methods in Locative Media Design." Journal of Media Innovations 2, no. 1 (2015): 107–22. http://dx.doi.org/10.5617/jmi.v2i1.893.
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Media design can be used for research purposes if it includes a clearly defined research question, and clear evaluation to see whether an answer to the research question has been found. Using a project with locative media for classical music communication as our example, we discuss common evaluation methods from the User Experience field, observing that they all tend to test “interface” and not “content.” Instead we propose three other methods of evaluation, that have a basis in humanist theories, such as textual analysis and genre studies: (1) Qualitative interviews with evaluators after the evaluation, asking them to describe the service in their own words, followed by a semantic analysis to get at how they have understood the service. (2) Within-subject A/B tests with alternative versions that are different in key aspects. (3) Peer review by experienced design researchers, who are likely to have a more fine-tuned vocabulary to express their opinions.
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Hussain, Mustafa I., Tera L. Reynolds, and Kai Zheng. "Medication safety alert fatigue may be reduced via interaction design and clinical role tailoring: a systematic review." Journal of the American Medical Informatics Association 26, no. 10 (2019): 1141–49. http://dx.doi.org/10.1093/jamia/ocz095.
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Abstract Objective Alert fatigue limits the effectiveness of medication safety alerts, a type of computerized clinical decision support (CDS). Researchers have suggested alternative interactive designs, as well as tailoring alerts to clinical roles. As examples, alerts may be tiered to convey risk, and certain alerts may be sent to pharmacists. We aimed to evaluate which variants elicit less alert fatigue. Materials and Methods We searched for articles published between 2007 and 2017 using the PubMed, Embase, CINAHL, and Cochrane databases. We included articles documenting peer-reviewed empirical research that described the interactive design of a CDS system, to which clinical role it was presented, and how often prescribers accepted the resultant advice. Next, we compared the acceptance rates of conventional CDS—presenting prescribers with interruptive modal dialogs (ie, “pop-ups”)—with alternative designs, such as role-tailored alerts. Results Of 1011 articles returned by the search, we included 39. We found different methods for measuring acceptance rates; these produced incomparable results. The most common type of CDS—in which modals interrupted prescribers—was accepted the least often. Tiering by risk, providing shortcuts for common corrections, requiring a reason to override, and tailoring CDS to match the roles of pharmacists and prescribers were the most common alternatives. Only 1 alternative appeared to increase prescriber acceptance: role tailoring. Possible reasons include the importance of etiquette in delivering advice, the cognitive benefits of delegation, and the difficulties of computing “relevance.” Conclusions Alert fatigue may be mitigated by redesigning the interactive behavior of CDS and tailoring CDS to clinical roles. Further research is needed to develop alternative designs, and to standardize measurement methods to enable meta-analyses.
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Corsaro, William A. "Big Ideas from Little People: What Research with Children Contributes to Social Psychology." Social Psychology Quarterly 83, no. 1 (2020): 5–25. http://dx.doi.org/10.1177/0190272520906412.
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Beginning in the 1970s, research in childhood studies led to the reevaluation of children’s agency and their contributions to society. In my work on children’s interactions with peers and adults in schools and families, I challenged traditional views of socialization offering the alternative view of interpretive reproduction and associated concepts of peer culture and priming events. I review the development of these concepts and the importance of longitudinal comparative ethnography and audiovisual recording for capturing how research with children contributes both to rigorous reexamination of socialization theory and the field of social psychology more generally. In particular, I focus on the expansion of two theoretical concepts in my work related to the general notion of interpretive reproduction: (1) nonlinear and collective reproductive versus linear stage views of socialization and human development and (2) micro dramas in collective routines in peer culture. In the review of my methods and theory and in the expansion of my theoretical concepts, I continually raise issues regarding reexamination of Mead’s play and game stage and for the need to radically alter or even abandon the traditional concept of socialization.
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Gilson, Carly B., Erik W. Carter, and Elizabeth E. Biggs. "Systematic Review of Instructional Methods to Teach Employment Skills to Secondary Students With Intellectual and Developmental Disabilities." Research and Practice for Persons with Severe Disabilities 42, no. 2 (2017): 89–107. http://dx.doi.org/10.1177/1540796917698831.
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Effective vocational instruction is an essential aspect of preparing students with intellectual and developmental disabilities (IDD) for the world of work. We systematically reviewed research on instructional methods used to teach employment skills to secondary students with IDD. We identified 56 studies involving 766 participants with IDD. Four intervention approaches emphasized technology or some other instructional stimulus (i.e., self-management devices, video-based, audio-based, picture and tactile-based) and four focused on live instructors (i.e., direct instruction, augmentative and alternative communication, simulation, peer-delivered). Among the 21 instructional methods used within these approaches, performance feedback, device-assisted instruction, response prompting, and community-based instruction were the most common. We address the extent to which these intervention approaches were effective across students, instructional methods, settings, and outcomes, as well as offer recommendations for future research and practice.
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Scott, Jacqueline, Ameet Singh, and Alexander Valverde. "Pneumoperitoneum in Veterinary Laparoscopy: A Review." Veterinary Sciences 7, no. 2 (2020): 64. http://dx.doi.org/10.3390/vetsci7020064.
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Objective: To review the effects of carbon dioxide pneumoperitoneum during laparoscopy, evaluate alternative techniques to establishing a working space and compare this to current recommendations in veterinary surgery. Study Design: Literature review. Sample Population: 92 peer-reviewed articles. Methods: An electronic database search identified human and veterinary literature on the effects of pneumoperitoneum (carbon dioxide insufflation for laparoscopy) and alternatives with a focus on adaptation to the veterinary field. Results: Laparoscopy is the preferred surgical approach for many human and several veterinary procedures due to the lower morbidity associated with minimally invasive surgery, compared to laparotomy. The establishment of a pneumoperitoneum with a gas most commonly facilitates a working space. Carbon dioxide is the preferred gas for insufflation as it is inert, inexpensive, noncombustible, colorless, excreted by the lungs and highly soluble in water. Detrimental side effects such as acidosis, hypercapnia, reduction in cardiac output, decreased pulmonary compliance, hypothermia and post-operative pain have been associated with a pneumoperitoneum established with CO2 insufflation. As such alternatives have been suggested such as helium, nitrous oxide, warmed and humidified carbon dioxide and gasless laparoscopy. None of these alternatives have found a consistent benefit over standard carbon dioxide insufflation. Conclusions: The physiologic alterations seen with CO2 insufflation at the current recommended intra-abdominal pressures are mild and of transient duration. Clinical Significance: The current recommendations in veterinary laparoscopy for a pneumoperitoneum using carbon dioxide appear to be safe and effective.
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Yousefi, Zohreh, Seyed Bagher Hosseini, Seyed Abbas Yazdanfar, and Saeid Norouzian-Maleki. "Designing Alternative Housing in an Old Context: Zargandeparsh, Tehran." Environment-Behaviour Proceedings Journal 1, no. 1 (2016): 269. http://dx.doi.org/10.21834/e-bpj.v1i1.223.
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Today, poor performance in old residential contexts in terms of memorable visual elements reduce the residents’ sense of belonging. The study used a combination of qualitative and quantitative research methods. To meet the needs of residents, a questionnaire was distributed among twenty-five experts. Data analysis was performed using fuzzy logic to calculate the weight of each criterion of hierarchical fuzzy (FAHP). According to the findings, the largest weight belonged to social interaction (0.288), physical (0.205) and dependence (0.179). The results showed that social interaction is imperative in increasing the residents’ sense of attachment.© 2016. The Authors. Published for AMER ABRA by e-International Publishing House, Ltd., UK. Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies, Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.Keywords: Housing; old texture; place; sense of attachment
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Moore, Sarah E., Megan McMullan, Claire T. McEvoy, Michelle C. McKinley, and Jayne V. Woodside. "The effectiveness of peer-supported interventions for encouraging dietary behaviour change in adults: a systematic review." Public Health Nutrition 22, no. 4 (2018): 624–44. http://dx.doi.org/10.1017/s1368980018003294.
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AbstractObjectiveThere is an urgent need to find effective methods of supporting individuals to make dietary behaviour changes. Peer-supported interventions (PSI) have been suggested as a cost-effective strategy to support chronic disease self-management. However, the effect of PSI on dietary behaviour is unclear. The present systematic review aimed to assess the effectiveness of PSI for encouraging dietary behaviour change in adults and to consider intervention characteristics linked with effectiveness.DesignElectronic databases were searched until June 2018 for randomised controlled trials assessing the effectiveness of PSI compared with an alternative intervention and/or control on a dietary related outcome in adults. Following title and abstract screening, two reviewers independently screened full texts and data were extracted by one reviewer and independently checked by another. Results were synthesised narratively.SettingRandomised controlled trials.ParticipantsAdult studies.ResultsThe fifty-four included studies varied in participants, intervention details and results. More PSI reported a positive or mixed effect on diet than no effect. Most interventions used a group model and were lay-led by peer supporters. Several studies did not report intervention intensity, fidelity and peer training and support in detail. Studies reporting positive effects employed more behaviour change techniques (BCT) than studies reporting no effect; however, heterogeneity between studies was considerable.ConclusionsAs evidence was mixed, further interventions need to assess the effect of PSI on dietary behaviour, describe intervention content (theoretical basis, BCT, intensity and peer training/support) and include a detailed process evaluation.
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Garcia Godoy, Laura R., Amy E. Jones, Taylor N. Anderson, et al. "Facial protection for healthcare workers during pandemics: a scoping review." BMJ Global Health 5, no. 5 (2020): e002553. http://dx.doi.org/10.1136/bmjgh-2020-002553.
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BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has led to personal protective equipment (PPE) shortages, requiring mask reuse or improvisation. We provide a review of medical-grade facial protection (surgical masks, N95 respirators and face shields) for healthcare workers, the safety and efficacy of decontamination methods, and the utility of alternative strategies in emergency shortages or resource-scarce settings.MethodsWe conducted a scoping review of PubMed and grey literature related to facial protection and potential adaptation strategies in the setting of PPE shortages (January 2000 to March 2020). Limitations included few COVID-19-specific studies and exclusion of non-English language articles. We conducted a narrative synthesis of the evidence based on relevant healthcare settings to increase practical utility in decision-making.ResultsWe retrieved 5462 peer-reviewed articles and 41 grey literature records. In total, we included 67 records which met inclusion criteria. Compared with surgical masks, N95 respirators perform better in laboratory testing, may provide superior protection in inpatient settings and perform equivalently in outpatient settings. Surgical mask and N95 respirator conservation strategies include extended use, reuse or decontamination, but these strategies may result in inferior protection. Limited evidence suggests that reused and improvised masks should be used when medical-grade protection is unavailable.ConclusionThe COVID-19 pandemic has led to critical shortages of medical-grade PPE. Alternative forms of facial protection offer inferior protection. More robust evidence is required on different types of medical-grade facial protection. As research on COVID-19 advances, investigators should continue to examine the impact on alternatives of medical-grade facial protection.
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Cuciureanu, Gheorghe. "Organization of research project competitions in the Republic of Moldova: lottery is better than incompetence and partiality." Akademos, no. 2(61) (September 2021): 37–47. http://dx.doi.org/10.52673/18570461.21.2-61.01.
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The paper analyzes the experience of evaluation and organization of research project competitions through the prism of the „State Program 2020–2023” competition held in the Republic of Moldova. The advantages and disadvantages of the two major evaluation methods are highlighted: peer review and bibliometric evaluation, but also alternative ways of evaluating and selecting projects. Taking into account the shortcomings established in the process of organizing national competitions, the author proposes the organization of competitions for research projects in the Republic of Moldova through a combination of bibliometric evaluation and a lottery.
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Ismail, Wan Ismahanisa, Mohamed Azmi Ahmad Hassali, Maryam Farooqui, Muhammad Nabil Fikri Roslan, and Nazri Che Dom. "Complementary and Alternative Medicine versus Conventional Medicine Use in Thalassemia Patients." Environment-Behaviour Proceedings Journal 6, no. 16 (2021): 105–11. http://dx.doi.org/10.21834/ebpj.v6i16.2665.
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Background: This study explores thalassemia patients' perceptions concerning the effectiveness of conventional therapies for Thalassemia healthcare. Method: The semi-structured interviews were audiotaped, transcribed verbatim, and translated into English. Results: Nearly all thalassemia patients reported to have relied on conventional treatment methods to treat and reduce the severity of their disease. Few patients reported not to comply with their treatment procedures due to fear of infection through blood transfusion, surgery and organ failure. Conclusions: In conclusion, patients showed positive views about the conventional therapies carried out for Thalassemia. Keywords:: Thalassemia; qualitative; conventional; complementary and alternative medicine eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v6i16.2665
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Hulett, Jennifer M., and Jane M. Armer. "A Systematic Review of Spiritually Based Interventions and Psychoneuroimmunological Outcomes in Breast Cancer Survivorship." Integrative Cancer Therapies 15, no. 4 (2016): 405–23. http://dx.doi.org/10.1177/1534735416636222.
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Objective. This is a review of spiritually based interventions (eg, mindfulness-based stress reduction) that utilized psychoneuroimmunological (PNI) outcome measures in breast cancer survivors. Specifically, this review sought to examine the evidence regarding relationships between spiritually based interventions, psychosocial-spiritual outcomes, and biomarker outcomes in breast cancer survivors. Methods. A systematic search of 9 online databases was conducted for articles of original research, peer-reviewed, randomized and nonrandomized control trials from 2005-2015. Data were extracted in order to answer selected questions regarding relationships between psychosocial-spiritual and physiological measures utilized in spiritually based interventions. Implications for future spiritually based interventions in breast cancer survivorship are discussed. Results. Twenty-two articles were reviewed. Cortisol was the most common PNI biomarker outcome studied. Compared with control groups, intervention groups demonstrated positive mental health outcomes and improved or stable neuroendocrine-immune profiles, although limitations exist. Design methods have improved with regard to increased use of comparison groups compared with previous reviews. There are few spiritually based interventions that specifically measure religious or spiritual constructs. Similarly, there are few existing studies that utilize standardized religious or spiritual measures with PNI outcome measures. Findings suggest that a body of knowledge now exists in support of interventions with mindfulness-breathing-stretching components; furthermore, these interventions appear to offer potential improvement or stabilization of neuroendocrine-immune activity in breast cancer survivors compared to control groups. Conclusion. From a PNI perspective, future spiritually based interventions should include standardized measures of religiousness and spirituality in order to understand relationships between and among religiousness, spirituality, and neuroendocrine-immune outcomes. Future research should now focus on determining the minimum dose and duration needed to improve or stabilize neuroendocrine-immune function, as well as diverse setting needs, including home-based practice for survivors who are too ill to travel to group sessions or lack economic resources.
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Prieto-Ayuso, Alejandro, Juan Carlos Pastor-Vicedo, Sixto González-Víllora, and Javier Fernández-Río. "Are Physical Education Lessons Suitable for Sport Talent Identification? A Systematic Review of the Literature." International Journal of Environmental Research and Public Health 17, no. 6 (2020): 1965. http://dx.doi.org/10.3390/ijerph17061965.
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Objectives: The goal of this study was to shed light on the existent knowledge, internationally published over the last decade (2009–2019), on how to deal with talented children in physical education (PE). Methods: A mixed systematic review (SR) was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and registered in the International Prospective Register of Systematic Reviews (PROSPERO), registration number: CRD42019117211. Study eligibility criteria: The articles included were selected using the following criteria: (a) studies published in peer-reviewed international journals; (b) studies published from 2009 to 2019 (both inclusive); (c) studies that included quantitative and/or qualitative methods and findings; (d) research conducted within school contexts; (e) articles that focused on both talent/gift and PE, and (f) studies published in English or Spanish. Results: A total of 11 articles were identified. Results showed a gradual change in both methods and instruments used for talent identification (TI) in PE, focused currently on children’s health and involvement in sports. Second, there is consensus on the lack of clarity in schools’ policies and guidelines on how to deal with talented children in PE. Conclusions: Finally, there are alternative programs to elite athlete models that better fit in PE to deal with talented children and to avoid child disengagement in PE and sports.
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Senanayake, Buddhika, Sumudu I. Wickramasinghe, Lars Eriksson, Anthony C. Smith, and Sisira Edirippulige. "Telemedicine in the correctional setting: A scoping review." Journal of Telemedicine and Telecare 24, no. 10 (2018): 669–75. http://dx.doi.org/10.1177/1357633x18800858.
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Introduction The access healthcare services to inmates within correctional settings has generally been low and problematic due to specific nature of the prison setting. Telemedicine has been used as an alternative delivery mode. This study aimed to collate the current evidence related to the use of telemedicine to deliver health services within correctional settings. Methods A comprehensive search of seven databases – PubMed, Embase, CINAHL, Informit, Cochrane Central Register of Controlled Trials, PsycINFO and Scopus, for peer-reviewed publications was conducted in April, 2018. Results Initial search identified 1147 articles. After review of the title and abstract, 36 articles were included in the final review. Of the included articles, 19 (53%) were published during the period of 2010-2018. Articles were predominantly from the USA ( n = 23; 64 %), France and Australia. There were 23 descriptive studies (64%), five costing studies (14%) five experimental studies (14%), two mixed methods (6%) and one qualitative study (3%). The experimental studies were predominantly focused on mental health services ( n = 4, 80%). The commonest telemedicine intervention used was synchronous videoconferencing ( n = 21, 58%), while eight articles (22%) described asynchronous interventions. Telemedicine interventions were mainly used for mental health ( n = 13), and ophthalmology ( n = 4) disciplines. Discussion In the right circumstances, telemedicine interventions within correctional settings seem to be a useful method in connecting inmates with essential health services.
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Ma, Bin, Fa-yong Ke, Er-liang Zheng, Zun-xian Yang, Qing-nan Tang, and Guo-qing Qi. "Endorsement of the Consort Statement by Chinese Journals of Traditional Chinese Medicine: A Survey of Journal Editors and Review of Journals— Instructions for Authors." Acupuncture in Medicine 34, no. 3 (2016): 178–83. http://dx.doi.org/10.1136/acupmed-2015-010870.
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Background We aimed to assess the endorsement of the Consolidation Standards of Reporting Trials (CONSORT) statement by Chinese journals of Traditional Chinese Medicine (TCM) and its incorporation into their editorial processes. Methods PubMed, Embase and major Chinese databases were searched to identify journals of TCM from China for inclusion. The latest ‘instruction for authors’ (IFA) of each included journal was obtained and any text mentioning CONSORT or CONSORT extension papers was extracted. Subsequently, the editor of each of the included journals was surveyed about their journal's endorsement of the CONSORT recommendations and their incorporation into editorial and peer review processes. Results Sixty-three journals of TCM from China were examined. Of these, only three (5%) and one (2%) of the 63 journals mentioned the CONSORT statement and extension papers, respectively, in their IFA. Fifty-four of 63 (86%) of surveyed journals responded, with the majority of respondents being editors. Only 20% (11/54) of the respondents reported that they had any knowledge of the CONSORT statement. Only 6% (3/54) of the editors reported that they required authors to comply with the CONSORT statement or that they incorporated it into their peer review and editorial processes. Conclusions TCM journals in China endorsing the CONSORT statement constituted a small percentage of the total. The majority of editors surveyed were not familiar with the content of the CONSORT statement and extension papers. We strongly recommend that the China Periodicals Association issue a policy to promote the endorsement of the CONSORT statement and conduct relevant training for journal editors in China.
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Rodrigues, Paulo, Johan Menten, and Chris Gastmans. "Physicians’ perceptions of palliative sedation for existential suffering: a systematic review." BMJ Supportive & Palliative Care 10, no. 2 (2019): 136–44. http://dx.doi.org/10.1136/bmjspcare-2019-001865.
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BackgroundPalliative sedation for existential suffering (PS-ES) is a controversial clinical intervention. Empirical studies about physicians’ perceptions do not converge in a clear position and current clinical practice guidelines do not agree either regarding this kind of intervention.AimTo gain deeper insight into physicians’ perceptions of PS-ES, the factors influencing it, the conditions for implementing it and the alternatives to it.DesignSystematic review of qualitative, quantitative and mixed-methods studies following the Peer Review Electronic Search Strategies and Preferred Reporting Items for Systematic Reviews and Meta-analyses protocols; quality appraisal and thematic synthesis methodology.Data sourcesSeven electronic databases (PubMed, CINAHL, Embase, Scopus, Web of Science, PsycINFO, PsycARTICLES) were exhaustively searched from inception through March 2019. Two reviewers screened paper titles, abstracts and full texts. We included only peer-reviewed journal articles published in English, French, German, Dutch, Spanish, Italian or Portuguese that focused on physicians’ perceptions of PS-ES.ResultsThe search yielded 17 publications published between 2002 and 2017. Physicians do not hold clear views or agree if and when PS-ES is appropriate. Case-related and individual-related factors that influenced physicians’ perceptions were identified. There is still no consensus regarding criteria to distinguish between necessary and sufficient conditions for invoking PS-ES. Some alternatives to PS-ES were identified.ConclusionsTo date, there is still no consensus on physicians’ perceptions of PS-ES. Further research is necessary to understand factors that influence physicians’ perceptions and philosophical-ethical presuppositions underlying this perceptions.
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Ashton, Melanie M., Michael Berk, Chee H. Ng, et al. "Nutraceuticals and nutritional supplements for the treatment of bipolar disorder: protocol for a systematic review." BMJ Open 9, no. 4 (2019): e025640. http://dx.doi.org/10.1136/bmjopen-2018-025640.
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IntroductionFirst line pharmacological treatments for bipolar disorder (BD) can leave shortfalls in recovery leading to patients seeking alternative and adjunctive treatments such as nutraceuticals. This protocol for a systematic review and proposed meta-analysis aims to answer the research question: in patients with BD, how does use of nutraceutical treatments compare with placebo in reducing depressive and mania symptoms?Methods and analysisClinical trials will be identified through database searches using PubMed via PubMed, EMBASE via embase.com, Cochrane Central Register of Controlled Clinical Trials (CENTRAL) via cochranelibrary.com and CINAHL Complete via EBSCO. Search terms for BD and specific nutraceuticals (75 total search terms) will be used. Double-blind, randomised, controlled, clinical trials of adults with BD will be included in the review. Risk of bias will be assessed using the Cochrane Collaboration’s tool for assessing risk of bias in randomised trials.Ethics and disseminationThis review will only look at published data (already reviewed for ethical compliance); therefore, ethical approval is not required. We aim to publish the systematic review in a peer-reviewed journal and present at conferences.PROSPERO registration numberCRD42019100745.
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Kam, Weng Yuen, Richard Built, Brandt Saxey, and Jerod Johnson. "Buckling-Restrained Braces (BRB) Seismic Design - A Consulting Engineer’s Consideration." Key Engineering Materials 763 (February 2018): 932–40. http://dx.doi.org/10.4028/www.scientific.net/kem.763.932.
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There is no standard for the design of Buckling-Restrained Braces (BRBs) frames in New Zealand. Consequently, a consulting engineer would need to consider a range of overseas design standards and latest research findings and incorporate into a New Zealand code-compliance framework. This “Alternative Solution” pathway to satisfy the New Zealand Building Code means peer review and agreement with peer review is required. This paper describes the design journey and technical challenges the authors had in the seismic design of the BRB for the New Zealand International Convention Centre (NZICC). BRB frames are used as the primary ductile lateral load bracing system, acting in parallel with the moment-resisting frames formed by the primary cruciform columns and storey-deep trusses. Due to the vertical irregularity and a dual-system structure, a direct displacement-based design (DDBD) approach was used in parallel with a more convention code-compliant force-based design, to derive the BRB design actions. The design of the BRB connections, in particular the gusset design is particularly challenging due to the diverging views and numerous methodologies available. We have considered several analytical methods for the BRB connection design and commissioned two full-scale testing of the critical BRB and the gusset connection. Lessons learnt
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Kundu, Shilpi, Mohammad Ehsanul Kabir, Edward A. Morgan, Peter Davey, and Moazzem Hossain. "Building Coastal Agricultural Resilience in Bangladesh: A Systematic Review of Progress, Gaps and Implications." Climate 8, no. 9 (2020): 98. http://dx.doi.org/10.3390/cli8090098.
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This paper presents the results of a systematic literature review of climate change adaptation and resilience in coastal agriculture in Bangladesh. It explores the existing adaptation measures against climatic stresses. It investigates the extent of resilience-building by the use of these adaptation measures and identifies major challenges that hinder the adaptation process within the country. The review was conducted by following the systematic methods of the protocol of Preferred Items for Systematic Review Recommendations (PRISMA) to comprehensively synthesize, evaluate and track scientific literature on climate-resilient agriculture in coastal Bangladesh. It considered peer-reviewed English language articles from the databases Scopus, Web of Science and Science Direct between the years 2000 and 2018. A total of 54 articles were selected following the four major steps of a systematic review, i.e., identification, screening, eligibility and inclusion. Adaptation measures identified in the review were grouped into different themes: Agricultural adaptation, alternative livelihoods, infrastructure development, technological advancement, ecosystem management and policy development. The review revealed that within the adaptation and resilience literature for coastal Bangladesh, maladaptation, gender imbalance and the notable absence of studies of island communities were gaps that require future research.
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Pestrikova, Tatiana Yu, Elena A. Yurasova, and Igor V. Yurasov. "A strategy of antimicrobial therapy of pelvic inflammatory diseases at antibiotic resistance of microbial pathogens." Gynecology 21, no. 1 (2019): 60–63. http://dx.doi.org/10.26442/20795696.2019.1.190237.
Full textAbstract:
Relevance. Antibiotic resistance of microbial pathogens is an interdisciplinary and interstate problem of major medical and socio-economic importance. If multiresistant microbial flora is detected in patients with acute or chronic forms of pelvic inflammatory diseases alternative antimicrobial combined therapy an advisability should be considered. Current trends of an increase in multiresistant gram-negative infections along with limited range of alternative treatment options dictate a need for further research. Study of alternative antibiotics effectiveness in pelvic inflammatory diseases treatment is necessary for a further development of optimal treatment regimens. Aim. To search for adequate combinations of antimicrobial therapy aimed at antibiotic-resistant pathogens. Materials and methods. To write this review a search for domestic and foreign publications in Russian and international search systems (PubMed, eLibrary, etc.) for the last 2-12 years was conducted. The review includes articles from peer-reviewed literature. Results. Fosfomycin possesses a broad spectrum of antibacterial effects including gram-positive and gram-negative aerobic bacteria. The drug is highly effective against Pseudomonas aeruginosa and Escherichia coli, anaerobic bacteria (Proteus mirabilis and Klebsiella pneumoniae) as well as against gram- positive bacteria (Staphylococcus spp., including S. aureus, S. epidermidis; Streptococcus spp., including Enterococcus faecalis). Conclusions. When multiresistant microbial flora is detected in patients with acute or chronic forms of pelvic inflammatory diseases an advisability of fosfomycin administration should be considered.
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Wang, James Wei, and Matthew Williams. "Exploring definitions of radiological sarcopenia in cancer: a protocol for a scoping review." BMJ Open 11, no. 7 (2021): e053076. http://dx.doi.org/10.1136/bmjopen-2021-053076.
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IntroductionSarcopenia is the loss of skeletal muscle volume or quality, a concept previously established in age-related frailty. Sarcopenia is part of the cancer cachexia syndrome and has therefore been explored as biomarker through the opportunistic measurement of skeletal muscle from routine cancer imaging. However, there is inconsistency in diagnostic landmarks and cut-offs. The most common assessment method is skeletal muscle area at the slice level of the third lumbar vertebrae divided by height squared. Alternative sarcopenia measures have been derived from morphological descriptions of the psoas, thoracic and cervical muscles, driven by tumour-specific anatomical imaging.Current tumour-site specific reviews suggest a link between heterogeneously defined sarcopenia on tumour site-specific outcomes. Because lack of uniformity, a scoping review is best suited to streamline anatomically based definitions and map the evidence to outcomes. The aim of this article is to describe a protocol for a scoping review that will homogenise the evidence of radiological sarcopenia in cancer. The extent, range and nature of reports will be examined, after which possible titles for potential systematic reviews identified.Methods and analysisWe will apply methods based on the Joanna Briggs Institute scoping review manual. Predefined search terms compiled with a librarian experienced in systematic reviews will be used to search PubMed/Medline, Embase, Scopus and Cochrane databases studies correlating cross-sectional cancer sarcopenia biomarkers with clinical outcomes. Studies will be mapped according to whether they have defined new sarcopenia measures or applied previous definitions to new populations, both with reported outcomes. This review will generate a numerical analysis on the extent of cancer sarcopenia measures as well as a narrative synthesis to describe the applications of radiologically derived sarcopenia in cancer.Ethics and disseminationFormal ethical approval was not required to undertake this scoping review. Findings will be published in peer-reviewed journals and conference presentations.
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Bae, Soohyun, Min-Ho Hong, Hyunwoo Lee, et al. "Reliability of Metal 3D Printing with Respect to the Marginal Fit of Fixed Dental Prostheses: A Systematic Review and Meta-Analysis." Materials 13, no. 21 (2020): 4781. http://dx.doi.org/10.3390/ma13214781.
Full textAbstract:
Three-dimensional (3D) printing technologies have been widely used to manufacture crowns and frameworks for fixed dental prostheses. This systematic review and meta-analysis aimed to assess the reliability of the marginal fit of 3D-printed cobalt-chromium-based fixed dental prostheses in comparison to conventional casting methods. Articles published until 25 June 2020, reporting the marginal fit of fixed prostheses fabricated with metal 3D printing, were searched using electronic literature databases. After the screening and quality assessment, 21 eligible peer-reviewed articles were selected. Meta-analysis revealed that the marginal gap of the prostheses manufactured using 3D printing was significantly smaller compared to that manufactured using casting methods (standard mean difference (95% CI): −0.92 (−1.45, −0.38); Z = −3.37; p = 0.0008). The estimated difference between the single and multi-unit types did not differ significantly (p = 0.3573). In the subgroup analysis for the measurement methods, the tendency of marginal discrepancy between the 3D printing and casting groups was significantly different between articles that used direct observation and those that used the silicone replica technique (p < 0.001). Metal 3D printing technologies appear reliable as an alternative to casting methods in terms of the fit of the fixed dental prostheses. In order to analyze the factors influencing manufacturing and confirm the results of this review, further controlled laboratory and clinical studies are required.
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Sealy, Madison, and Rachelle Hollier. "Appropriateness of oral clopidogrel for prehospital STEMI management." International Paramedic Practice 11, no. 1 (2021): 4–14. http://dx.doi.org/10.12968/ippr.2021.11.1.4.
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Introduction: Clopidogrel is an anticoagulant commonly used in the prehospital environment for the management of ST-elevation myocardial infarction (STEMI). Some ambulance services have incorporated this into their treatment regimens; however, others hold a variety of alternative pharmacological interventions. Aims: The purpose of this study is to examine and determine the pharmacological efficacy and safety of clopidogrel in the management of patients with STEMI and assess whether ambulance services should use the drug as part of standard practice. Methods: A literature review was conducted to identify articles relating to the administration of clopidogrel in the prehospital setting. Fourteen peer-reviewed journal articles and eight clinical practice guidelines from international ambulance services were included in this review. Results: According to this literature review, clopidogrel has been deemed safe, effective and practical for widespread use in the prehospital environment for the management of STEMI. However, some disagreement has arisen over whether clopidogrel is a more favourable anticoagulant than ticagrelor and prasugrel. Conclusion: Anticoagulants such as clopidogrel should be strongly considered as a standard treatment regimen in the prehospital management of STEMI across international jurisdictions.
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Heron, Dwight Earl, Sushil Beriwal, Hans Benson, Zach Lorinc, Amanda Barry, and Kathleen Lokay. "The benefits of clinical pathways (CP) for radiation oncology in a large cancer care network." Journal of Clinical Oncology 34, no. 7_suppl (2016): 148. http://dx.doi.org/10.1200/jco.2016.34.7_suppl.148.
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148 Background: UPMC CancerCenter and the University of Pittsburgh Cancer Institute (UPMC) created a radiation oncology CP program (now incorporated separately as Via Pathways) in 2003 to standardize care at 19 radiation sites. The program exists to ensure consistency and rapid adoption of best evidence-based care in a large, integrated NCI-designated comprehensive cancer center. Methods: The web-based CP portal integrates with electronic medical records to provide point-of-care patient-specific decision support. CP content is developed and maintained by committees of oncologists culled from the network. Meetings occur semi-annually to review and update treatment recommendations for the nearly 95% of cancers covered. Evidence is evaluated hierarchically on efficacy, toxicity, then cost. When the committee modifies CP content, the software is updated within 35 days and new recommendations are available to the 38 network providers. Through analysis of the utilization data, leaders can monitor adherence to the CP recommendations and research practice patterns at an unprecedented level of granularity. Results: Since data collection in the portal began in 2009, UPMC has captured over 48,000 visits and adhered to CP recommendations 96% of the time. Off-pathway decisions were approved prior to treatment by a designated peer review radiation oncologist at UPMC. Reasons for going off pathway and the alternative approach to care were recorded. Efforts to increase efficiencies and trial accruals have been successful due in large part to access to such a vast and comprehensive database. Conclusions: CP are an integral part of standardizing to high-value care across large networks and geographic regions. The committee process, rapid electronic deployment, and easy access to evidence reviews have garnered high physician buy-in and consistent adherence to CP recommendations. Other benefits of the program include: a transition from volume to value care models; facilitation of onboarding new physicians, residency trainees, and fellows; providing transparency through peer review, a committee process, and evidence reviews. CP are now used by more than 1000 physicians across the US in a variety of academic and community settings.
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MARINOU (Κ. ΜΑΡΙΝΟΥ), K., and I. DONTA (Ι. ΔΟΝΤΑ). "Ethics of experimentation. Ethical review of experimental research protocols." Journal of the Hellenic Veterinary Medical Society 60, no. 3 (2017): 217. http://dx.doi.org/10.12681/jhvms.14928.
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This paper describes a set of principles for the conduct of ethical review regarding experiments carried out on laboratory animals, which is important to be maintained from researchers throughout the whole process, from the initial design of the experimental protocol up to the publication of results in a peer-reviewed journal. Animal use should be justified after thorough examination of the existing validated alternative methods. The ethical review of experimental protocols will very soon become obligatory as the revision of the European Directive 86/609/EEC, regarding the protection and welfare of experimental animals, and the process will be clearly defined. In Greece several ethical committees have already been established in academic and research institutions that review applications submitted by researchers who have to prove that they are aware of all ethical aspects of animal experimentation, including a harm/benefit analysis where special attention to the severity of the procedure is given. Ethical committees are responsible for the initial ethical evaluation of research protocols that plan to use laboratory animals and for ensuring that animal welfare considerations are applied. Ethical committees may comprise experts from various scientific fields, among which the participation of a veterinarian specialized in Laboratory Animal Science and Medicine is considered to be essential. The ethical evaluation process needs to become a vital necessity for all researchers wishing to deal with Laboratory Animal Science and biomedical research.
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Lee, Yang Yang, and Zaini Abdul Halim. "Stochastic computing in convolutional neural network implementation: a review." PeerJ Computer Science 6 (November 9, 2020): e309. http://dx.doi.org/10.7717/peerj-cs.309.
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Stochastic computing (SC) is an alternative computing domain for ubiquitous deterministic computing whereby a single logic gate can perform the arithmetic operation by exploiting the nature of probability math. SC was proposed in the 1960s when binary computing was expensive. However, presently, SC started to regain interest after the widespread of deep learning application, specifically the convolutional neural network (CNN) algorithm due to its practicality in hardware implementation. Although not all computing functions can translate to the SC domain, several useful function blocks related to the CNN algorithm had been proposed and tested by researchers. An evolution of CNN, namely, binarised neural network, had also gained attention in the edge computing due to its compactness and computing efficiency. This study reviews various SC CNN hardware implementation methodologies. Firstly, we review the fundamental concepts of SC and the circuit structure and then compare the advantages and disadvantages amongst different SC methods. Finally, we conclude the overview of SC in CNN and make suggestions for widespread implementation.
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Tee, Xue Ting, Wirawahida Kamarulzaman, and Tjin Ai Tan Joanna. "A Systematic Review of Self-Coping Strategies Used by University Students to Cope with Public Speaking Anxiety." English Language Teaching 13, no. 10 (2020): 57. http://dx.doi.org/10.5539/elt.v13n10p57.
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Despite a growing body of research on instructor techniques and treatments to mitigate public speaking anxiety, this issue remains prominent, especially among university students. An alternative to mitigating such anxiety is to identify authentic coping strategies that university students could practice in actual situations. Numerous studies have attempted to explore students&rsquo; personal and social factors with the objective of suggesting suitable coping strategies to reduce the fear of public speaking. This paper reviews the existing evidence to understand the complexities of strategies that university students use to reduce their fear of public speaking. &nbsp;Nine peer-reviewed studies published between 2015 and 2020 were selected for this review from Science Direct and Google Scholar, using search terms such as &ldquo;public speaking anxiety&rdquo; and &ldquo;coping strategies.&rdquo; The analysis revealed that university students who (a) had an intermediate level of English language proficiency and a high level of speaking anxiety adopted both compensation and metacognitive strategies; (b) had a high level of English language proficiency and speaking anxiety adopted the affective strategy; and (c) had a high level of speaking anxiety and were exposed to full English medium instruction contexts adopted both social and memory strategies. This review, therefore, provides a better understanding of how university students cope with public speaking anxiety and at the same time urges educators to refine their pedagogical methods to lower the psychological barrier of speaking.
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Mutono, Nyamai, James Wright, Henry Mutembei, et al. "The nexus between water sufficiency and water-borne diseases in cities in Africa: a scoping review protocol." AAS Open Research 3 (May 5, 2020): 12. http://dx.doi.org/10.12688/aasopenres.13063.1.
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Introduction: Currently, an estimated two thirds of the world population is water insufficient. As of 2015, one out of every five people in developing countries do not have access to clean sufficient drinking water. In an attempt to share the limited resource, water has been distributed at irregular intervals in cities in developing countries. Residents in these cities seek alternative water sources to supplement the inadequate water supplied. Some of these alternative sources of water are unsafe for human consumption, leading to an increased risk in water-borne diseases. Africa contributes to 53% of the diarrheal cases reported globally, with contaminated drinking water being the main source of transmission. Water-borne diseases like diarrhea, cholera, typhoid, amoebiasis, dysentery, gastroenteritis, cryptosporidium, cyclosporiasis, giardiasis, guinea worm and rotavirus are a major public health concern. The main objective of this scoping review is to map the available evidence to understand the sources of water among residents in cities in Africa and the relationship between clean water sufficiency and water-borne diseases in urban Africa. Methods and analysis: The search strategy will identify studies published in scientific journals and reports that are directly relevant to African cities that have a population of more than half a million residents as of 2014 AND studies on the ten emerging water-borne diseases, which are diarrhea, cholera, typhoid, amoebiasis, dysentery, gastroenteritis, cryptosporidium, cyclosporiasis, giardiasis, guinea worm and rotavirus. Ethics and dissemination: This scoping review did not require any formal ethical approval. The findings will be published in a peer-reviewed journal.
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Mathie, Robert, Yvonne Fok, Petter Viksveen, Aaron To, and Jonathan Davidson. "Systematic Review and Meta-Analysis of Randomised, Other-than-Placebo Controlled, Trials of Non-Individualised Homeopathic Treatment." Homeopathy 108, no. 02 (2019): 088–101. http://dx.doi.org/10.1055/s-0038-1677481.
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Introduction This study focuses on randomised controlled trials (RCTs) of non-individualised homeopathic treatment (NIHT) in which the control (comparator) group was other than placebo (OTP). Objectives To determine the comparative effectiveness of NIHT on health-related outcomes in adults and children for any given condition that has been the subject of at least one OTP-controlled trial. For each study, to assess its risk of bias and to determine whether its study attitude was predominantly ‘pragmatic’ or ‘explanatory’. Methods Systematic review. For each eligible trial, published in the peer-reviewed literature up to the end of 2016, we assessed its risk of bias (internal validity) using the seven-domain Cochrane tool, and its relative pragmatic or explanatory attitude (external validity) using the 10-domain PRECIS tool. We grouped RCTs by whether these examined IHT as alternative treatment (study design 1a), adjunctively with another intervention (design 1b), or compared with no intervention (design 2). RCTs were sub-categorised as superiority trials or equivalence/non-inferiority trials. For each RCT, we designated a single ‘main outcome measure’ to use in meta-analysis: ‘effect size’ was reported as odds ratio (OR; values > 1 favouring homeopathy) or standardised mean difference (SMD; values < 0 favouring homeopathy). Results Seventeen RCTs, representing 15 different medical conditions, were eligible for study. Three of the trials were more pragmatic than explanatory, two were more explanatory than pragmatic, and 12 were equally pragmatic and explanatory. Fourteen trials were rated ‘high risk of bias’ overall; the other three trials were rated ‘uncertain risk of bias’ overall. Ten trials had data that were extractable for analysis. Significant heterogeneity undermined the planned meta-analyses or their meaningful interpretation. For the three equivalence or non-inferiority trials with extractable data, the small, non-significant, pooled effect size (SMD = 0.08; p = 0.46) was consistent with a conclusion that NIHT did not differ from treatment by a comparator (Ginkgo biloba or betahistine) for vertigo or (cromolyn sodium) for seasonal allergic rhinitis. Conclusions The current data preclude a decisive conclusion about the comparative effectiveness of NIHT. Generalisability of findings is restricted by the limited external validity identified overall. The highest intrinsic quality was observed in the equivalence and non-inferiority trials of NIHT.
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McCutchan, Grace, Bahr Weiss, Harriet Quinn-Scoggins, et al. "Psychosocial influences on help-seeking behaviour for cancer in low-income and lower middle-income countries: a mixed-methods systematic review." BMJ Global Health 6, no. 2 (2021): e004213. http://dx.doi.org/10.1136/bmjgh-2020-004213.
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IntroductionStarting cancer treatment early can improve outcomes. Psychosocial factors influencing patients’ medical help-seeking decisions may be particularly important in low and lower middle-income countries (LMIC) where cancer outcomes are poor. Comprehensive review evidence is needed to understand the psychosocial influences on medical help-seeking for cancer symptoms, attendance for diagnosis and starting cancer treatment.MethodsMixed-methods systematic review registered on PROSPERO (CRD42018099057). Peer-reviewed databases were searched until April 2020 for studies assessing patient-related barriers and facilitators to medical help-seeking for cancer symptoms, diagnosis and treatment in adults (18+ years) living in LMICs. Quality of included studies was assessed using the Critical Appraisal Skills Programme tool. Data were synthesised using meta-analytic techniques, meta-ethnography or narrative synthesis as appropriate.ResultsOf 3963 studies identified, 64 were included. In quantitative studies, use of traditional, complementary and alternative medicine (TCAM) was associated with 3.60 higher odds of prolonged medical help-seeking (95% CI 2.06 to 5.14). Qualitative studies suggested that use of TCAM was a key barrier to medical help-seeking in LMICs, and was influenced by causal beliefs, cultural norms and a preference to avoid biomedical treatment. Women face particular barriers, such as needing family permission for help-seeking, and higher stigma for cancer treatment. Additional psychosocial barriers included: shame and stigma associated with cancer such as fear of social rejection (eg, divorce/disownment); limited knowledge of cancer and associated symptoms; and financial and access barriers associated with travel and appointments.ConclusionDue to variable quality of studies, future evaluations would benefit from using validated measures and robust study designs. The use of TCAM and gender influences appear to be important barriers to help-seeking in LMIC. Cancer awareness campaigns developed with LMIC communities need to address cultural influences on medical help-seeking behaviour.
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Frisch, Noreen Cavan, and David Rabinowitsch. "What’s in a Definition?Holistic Nursing, Integrative Health Care, andIntegrative Nursing: Report of an Integrated Literature Review." Journal of Holistic Nursing 37, no. 3 (2019): 260–72. http://dx.doi.org/10.1177/0898010119860685.
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Background: Nurses and others have used various terms to describe our caring/healing approach to practice. Because terms used can influence our image of ourselves and the image others have of us, we sought to clarify their meanings. Questions: How are the terms holistic nursing, integrative health care, and integrative nursing defined or described? Do we identify with these definitions/descriptions? Are the various terms the same or are they distinct? Method: We conducted an integrated review of peer-reviewed literature following the process described by Whittemore and Knafl. Using standard search methods, we reviewed full texts of 94 published papers and extracted data from 58 articles. Findings: Holistic describes “whole person care” often acknowledging body–mind–spirit. Holistic nursing defines a disciplinary practice specialty. The term integrative refers to practice that includes two or more disciplines or distinct approaches to care. Both terms, integrative and holistic, are associated with alternative/complementary modalities and have similar philosophical and/or theoretical underpinnings. Conclusions: There is considerable overlap between holistic nursing and integrative nursing. The relationship of integrative nursing to integrative health care is unclear based solely on definitions. Consideration of terms used provides opportunities for reflection, collaboration, and growth.
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Mutono, Nyamai, James Wright, Henry Mutembei, et al. "The nexus between improved water supply and water-borne diseases in urban areas in Africa: a scoping review protocol." AAS Open Research 3 (December 8, 2020): 12. http://dx.doi.org/10.12688/aasopenres.13063.2.
Full textAbstract:
Introduction: Currently, an estimated two thirds of the world population is water insufficient. As of 2015, one out of every five people in developing countries do not have access to clean sufficient drinking water. In an attempt to share the limited resource, water has been distributed at irregular intervals in cities in developing countries. Residents in these cities seek alternative water sources to supplement the inadequate water supplied. Some of these alternative sources of water are unsafe for human consumption, leading to an increased risk in water-borne diseases. Africa contributes to 53% of the diarrheal cases reported globally, with contaminated drinking water being the main source of transmission. Water-borne diseases like diarrhea, cholera, typhoid, amoebiasis, dysentery, gastroenteritis, cryptosporidium, cyclosporiasis, giardiasis, guinea worm and rotavirus are a major public health concern. The main objective of this scoping review is to map the available evidence to understand the sources of water among residents in cities in Africa and the relationship between clean water sufficiency and water-borne diseases in urban Africa. Methods and analysis: The search strategy will identify studies published in scientific journals and reports that are directly relevant to African cities that have a population of more than half a million residents as of 2014 AND studies on the ten emerging water-borne diseases, which are diarrhea, cholera, typhoid, amoebiasis, dysentery, gastroenteritis, cryptosporidium, cyclosporiasis, giardiasis, guinea worm and rotavirus. Ethics and dissemination: This scoping review did not require any formal ethical approval. The findings will be published in a peer-reviewed journal.
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Saffi, Hillah, Thien Phu Do, Jakob Møller Hansen, David W. Dodick, and Messoud Ashina. "The migraine landscape on YouTube: A review of YouTube as a source of information on migraine." Cephalalgia 40, no. 12 (2020): 1363–69. http://dx.doi.org/10.1177/0333102420943891.
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Introduction YouTube is the most widely used video hosting website in the world; however, the quality and reliability of information is unknown. The aim of this study is to evaluate the content and distribution of the most popular videos on YouTube about migraine. Methods We searched for migraine-related videos on the online video hosting resource YouTube ( http://youtube.com/ ). Two authors screened the titles and video descriptions independently for all videos with a view count of ≥ 10,000 views. For each video we recorded descriptive data, the source/author and the primary purpose/content. Results We identified 351 eligible videos. In total, there was more than 3 days of content viewed more than 163 million times. Only 9% of these videos were authored by healthcare professionals. The majority (44%) of videos focused on complementary and alternative medicine. Discussion YouTube provides a wide array of easily accessible information on migraine, ranging from authoritative sources to potentially questionable content. If used uncritically, this may result in inadequate clinical management. Peer-reviewed information on migraine mechanisms and treatment is needed to provide the best available evidence for the public and patients. Ideally, a professional society or foundation such as the International Headache Society would develop, curate, and distribute content.
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Xu, Sheng, LuYu Zhou, Murugavel Ponnusamy, et al. "A comprehensive review of circRNA: from purification and identification to disease marker potential." PeerJ 6 (August 24, 2018): e5503. http://dx.doi.org/10.7717/peerj.5503.
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Circular RNA (circRNA) is an endogenous noncoding RNA with a covalently closed cyclic structure. Based on their components, circRNAs are divided into exonic circRNAs, intronic circRNAs, and exon-intron circRNAs. CircRNAs have well-conserved sequences and often have high stability due to their resistance to exonucleases. Depending on their sequence, circRNAs are involved in different biological functions, including microRNA sponge activity, modulation of alternative splicing or transcription, interaction with RNA-binding proteins, and rolling translation, and are a derivative of pseudogenes. CircRNAs are involved in the development of a variety of pathological conditions, such as cardiovascular diseases, diabetes, neurological diseases, and cancer. Emerging evidence has shown that circRNAs are likely to be new potential clinical diagnostic markers or treatments for many diseases. Here we describe circRNA research methods and biological functions, and discuss the potential relationship between circRNAs and disease progression.
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Ulbrich-Zürni, Susanne, Petter Viksveen, E. Roberts, et al. "Systematic Review and Meta-Analysis of Randomised, Other-than-Placebo Controlled, Trials of Individualised Homeopathic Treatment." Homeopathy 107, no. 04 (2018): 229–43. http://dx.doi.org/10.1055/s-0038-1667129.
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Background This study focuses on randomised controlled trials (RCTs) of individualised homeopathic treatment (IHT) in which the control (comparator) group was other than placebo (OTP). Aims To determine the comparative effectiveness of IHT on health-related outcomes in adults and children for any clinical condition that has been the subject of at least one OTP-controlled trial. For each study, to assess the risk of bias and to determine whether its study attitude was predominantly ‘pragmatic’ or ‘explanatory’. Methods Systematic review. For each eligible trial, published in the peer-reviewed literature up to the end of 2015, we assessed its risk of bias (internal validity) using the seven-domain Cochrane tool, and its relative pragmatic or explanatory attitude (external validity) using the 10-domain PRECIS tool. We grouped RCTs by whether they examined IHT as an alternative treatment (study design Ia), adjunctively with another intervention (design Ib), or compared with a no-intervention group (design II). For each RCT, we identified a ‘main outcome measure’ to use in meta-analysis: ‘relative effect size’ was reported as odds ratio (OR; values >1 favouring homeopathy) or standardised mean difference (SMD; values < 0 favouring homeopathy). Results Eleven RCTs, representing 11 different medical conditions, were eligible for study. Five of the RCTs (four of which in design Ib) were judged to have pragmatic study attitude, two were explanatory, and four were equally pragmatic and explanatory. Ten trials were rated ‘high risk of bias’ overall: one of these, a pragmatic study with design Ib, had high risk of bias solely regarding participant blinding (a bias that is intrinsic to such trials); the other trial was rated ‘uncertain risk of bias’ overall. Eight trials had data that were extractable for analysis: for four heterogeneous trials with design Ia, the pooled OR was statistically non-significant; collectively for three clinically heterogeneous trials with design Ib, there was a statistically significant SMD favouring adjunctive IHT; in the remaining trial of design 1a, IHT was non-inferior to fluoxetine in the treatment of depression. Conclusions Due to the low quality, the small number and the heterogeneity of studies, the current data preclude a decisive conclusion about the comparative effectiveness of IHT. Generalisability of findings is limited by the variable external validity identified overall; the most pragmatic study attitude was associated with RCTs of adjunctive IHT. Future OTP-controlled trials in homeopathy should aim, as far as possible, to promote both internal validity and external validity.
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Uçar, Yurdanur, and William A. Brantley. "Biocompatibility of Dental Amalgams." International Journal of Dentistry 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/981595.
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Objective. The purpose of this review paper is to review the literature regarding the toxicology of mercury from dental amalgam and evaluate current statements on dental amalgam.Materials and Methods. Two key-words “dental amalgam” and “toxicity” were used to search publications on dental amalgam biocompatibility published in peer-reviewed journals written in English. Manual search was also conducted. The most recent declarations and statements were evaluated using information available on the internet. Case reports were excluded from the study.Results. The literature show that mercury released from dental amalgam restorations does not contribute to systemic disease or systemic toxicological effects. No significant effects on the immune system have been demonstrated with the amounts of mercury released from dental amalgam restorations. Only very rarely have there been reported allergic reactions to mercury from amalgam restorations. No evidence supports a relationship between mercury released from dental amalgam and neurological diseases. Almost all of the declarations accessed by the internet stated by official organizations concluded that current data are not sufficient to relate various complaints and mercury release from dental amalgam.Conclusions. Available scientific data do not justify the discontinuation of amalgam use from dental practice or replacement with alternative restorative dental materials.
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Oates, Lloyd L., Nima Moghaddam, Nikos Evangelou, and Roshan das Nair. "Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review." Clinical Rehabilitation 34, no. 3 (2019): 310–19. http://dx.doi.org/10.1177/0269215519896404.
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Objective: To evaluate the effectiveness of behavioural activation interventions for people with neurological conditions with comorbid depression, and explore content and adaptations. Data sources: PsycINFO, MEDLINE, CINAHL, AMED, and EMBASE databases were searched on the 19 November 2019. Reference lists of selected full-texts were screened by title. Review methods: We included peer-reviewed studies published in English that used behavioural activation for treatment of depression in adults with a neurological condition. Single-case reports, reviews, and grey literature were excluded. Methodological quality was assessed by two authors independently, and quality was appraised using Critical Appraisal Skills Programme checklists. Results: From 2714 citations, 10 articles were included comprising 590 participants. Behavioural activation was used to treat depression in people with dementia ( n = 4), stroke ( n = 3), epilepsy ( n = 1), Parkinson’s disease ( n = 1), and brain injury ( n = 1). Sample size ranged from 4 to 105 participants. There were seven randomized controlled studies; however, no studies compared behavioural activation to an alternative psychological therapy. The effect sizes varied between small and large in the studies where effect size could be calculated ( d = 0.24–1.7). Methodological quality of the included studies was variable. Intervention components were identifying and engaging in pleasurable activities, psychoeducation, and problem-solving. Adaptations included delivering sessions via telephone, delivering interventions via primary caregivers, and giving psychoeducation to caregivers. Conclusion: The effectiveness of behavioural activation in randomized controlled trials varied from small to large ( d = 0.24–1.7) in reducing depression. The content of behavioural activation was comparable to established treatment manuals. Adaptations appeared to support individuals to engage in therapy. Review registration: PROSPERO 2018, CRD42018102604.
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Fixsen, Alison. "Homeopathy in the Age of Antimicrobial Resistance: Is It a Viable Treatment for Upper Respiratory Tract Infections?" Homeopathy 107, no. 02 (2018): 099–114. http://dx.doi.org/10.1055/s-0037-1621745.
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Background Acute upper respiratory tract infections (URTIs) and their complications are the most frequent cause of antibiotic prescribing in primary care. With multi-resistant organisms proliferating, appropriate alternative treatments to these conditions are urgently required. Homeopathy presents one solution; however, there are many methods of homeopathic prescribing. This review of the literature considers firstly whether homeopathy offers a viable alternative therapeutic solution for acute URTIs and their complications, and secondly how such homeopathic intervention might take place. Method Critical review of post 1994 clinical studies featuring homeopathic treatment of acute URTIs and their complications. Study design, treatment intervention, cohort group, measurement and outcome were considered. Discussion focused on the extent to which homeopathy is used to treat URTIs, rate of improvement and tolerability of the treatment, complications of URTIs, prophylactic and long-term effects, and the use of combination versus single homeopathic remedies. Results Multiple peer-reviewed studies were found in which homeopathy had been used to treat URTIs and associated symptoms (cough, pharyngitis, tonsillitis, otitis media, acute sinusitis, etc.). Nine randomised controlled trials (RCTs) and 8 observational/cohort studies were analysed, 7 of which were paediatric studies. Seven RCTs used combination remedies with multiple constituents. Results for homeopathy treatment were positive overall, with faster resolution, reduced use of antibiotics and possible prophylactic and longer-term benefits. Conclusions Variations in size, location, cohort and outcome measures make comparisons and generalisations concerning homeopathic clinical trials for URTIs problematic. Nevertheless, study findings suggest at least equivalence between homeopathy and conventional treatment for uncomplicated URTI cases, with fewer adverse events and potentially broader therapeutic outcomes. The use of non-individualised homeopathic compounds tailored for the paediatric population merits further investigation, including through cohort studies. In the light of antimicrobial resistance, homeopathy offers alternative strategies for minor infections and possible prevention of recurring URTIs.
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Norman, Mohd Paidi, Mohd Zaid Daud, Mohd Solahuddin Shahruddin, and Sharifah Fadylawaty Syed Abdullah. "Determination of Zone-based Solah Times: A practice in Malaysia." Environment-Behaviour Proceedings Journal 6, SI4 (2021): 185–90. http://dx.doi.org/10.21834/ebpj.v6isi4.2918.
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Zone-based solah times depend on the Earth's orbital movement around the sun. JAKIM has introduced zone-based solah times prescribes the times for the zones or areas. Nevertheless, the on-site calculation of zonal solah times is often informed by geographical and state Islamic affairs administrations. This study aims to survey the practices and methods employed to determine the Malaysian states' zonal solah times, using library research and interview approaches. The findings indicated that two typical methods used are the Westernmost Point and Multipoint Reference. Another alternative method provided by Falak experts is Isotime. Keywords: Zones Solah Times, Multi-Point Reference, West-most Point eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v6iSI4.2918
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Benkendorff, K. "The need for more stringent requirements in Environmental Impact Assessment: Shell Cove Marina case study." Pacific Conservation Biology 5, no. 3 (1999): 214. http://dx.doi.org/10.1071/pc990214.
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An examination of Environmental Impact Statements (EIS) points to a clear need for change in the current process of Environmental Impact Assessment (EIA) in Australia. The recent approval of a Boatharbour/Marina at Shellharbour, New South Wales, Australia, serves as an example that underscores some of the problems common to most EISs. Budgetary constraints imposed on the ecological consultants can lead to the use of inappropriate methodology and the collection of inaccurate biological data. The limitations in methodology must be taken into consideration in EISs and all conclusions should be substantiated with data or reference to the literature. There is a need for stricter guidelines for ecological studies and monitoring programmes. A comprehensive list of potential impacts requiring consideration in an EIS should be provided for all designated developments. Novel mitigation methods should always be subject to monitoring. The consequences of not proceeding with the development should be considered in conjunction with alternatives to the proposed development and it should be essential to consider ecotourism as an alternative to all purely tourist oriented proposals. There is a need for peer review in the EIA process. Many of the flaws in the Shell Cove EIS might have been negated by more input from independent scientists. The future of ecologically sustainable development in Australia depends on our ability to learn from, and improve on, mistakes from the past.
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Woodside, Jayne V., Ian S. Young, and Michelle C. McKinley. "Fruits and vegetables: measuring intake and encouraging increased consumption." Proceedings of the Nutrition Society 72, no. 2 (2013): 236–45. http://dx.doi.org/10.1017/s0029665112003059.
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A high intake of fruit and vegetables (FV) is associated with reduced risk of chronic disease, although the evidence base is mostly observational. Blood biomarkers offer an objective indicator of FV intake, potentially improving estimates of intakes based on traditional methods. A valid biomarker of overall FV intake would be able to confirm population intakes, more precisely evaluate the association between intakes and health outcomes and confirm compliance in FV interventions. Several substances have been proposed as biomarkers of FV intake: vitamin C, the carotenoids and polyphenols. Certain biomarkers are strong predictors of single FV; however, the proposed single biomarkers of FV consumption are only modestly predictive of overall FV consumption. This is likely to be due to the complexity of the FV food group. While accurately measuring FV intake is important in nutrition research, another critical question is: how best can an increase in FV intake be achieved? Increased FV intake has been achieved in efficacy studies using intensive dietary advice. Alternative, less intensive methods for encouraging FV consumption need to be developed and tested for population level intervention. Systematic reviews suggest peer support to be an effective strategy to promote dietary change. This review will describe the evidence for a link between increased FV intake and good health, outline possible novel biomarkers of FV consumption, present the most recently available data on population intake of FV and examine the usefulness of different approaches to encourage increased consumption of FV.
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Rapinesi, Chiara, Georgios D. Kotzalidis, Stefano Ferracuti, Gabriele Sani, Paolo Girardi, and Antonio Del Casale. "Brain Stimulation in Obsessive-Compulsive Disorder (OCD): A Systematic Review." Current Neuropharmacology 17, no. 8 (2019): 787–807. http://dx.doi.org/10.2174/1570159x17666190409142555.
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Background: Obsessive-compulsive disorder (OCD) is a highly prevalent, severe, and chronic disease. There is a need for alternative strategies for treatment-resistant OCD. Objective: This review aims to assess the effect of brain stimulation techniques in OCD. Methods: We included papers published in peer-reviewed journals dealing with brain stimulation techniques in OCD. We conducted treatment-specific searches for OCD (Technique AND ((randomized OR randomised) AND control* AND trial) AND (magnetic AND stimulation OR (rTMS OR dTMS)) AND (obsess* OR compuls* OR OCD)) on six databases, i.e., PubMed, Cochrane, Scopus, CINAHL, PsycINFO, and Web of Science to identify randomised controlled trials and ClinicalTrials.gov for possible additional results. Results: Different add-on stimulation techniques could be effective for severely ill OCD patients unresponsive to drugs and/or behavioural therapy. Most evidence regarded deep brain stimulation (DBS) and transcranial magnetic stimulation (TMS), while there is less evidence regarding transcranial direct current stimulation (tDCS), electroconvulsive therapy, and vagus nerve stimulation (for these last two there are no sham-controlled studies). Low-frequency TMS may be more effective over the supplementary motor area or the orbitofrontal cortex. DBS showed best results when targeting the crossroad between the nucleus accumbens and the ventral capsule or the subthalamic nucleus. Cathodal tDCS may be better than anodal in treating OCD. Limitations. We had to include methodologically inconsistent underpowered studies. Conclusion: Different brain stimulation techniques are promising as an add-on treatment of refractory OCD, although studies frequently reported inconsistent results. TMS, DBS, and tDCS could possibly find some use with adequate testing, but their standard methodology still needs to be established.
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Zhai, Jingbo, Yan Li, Jingyi Lin, Shuo Dong, Jinhua Si, and Junhua Zhang. "Chinese herbal medicine for postpartum constipation: a protocol of systematic review and meta-analysis." BMJ Open 9, no. 1 (2019): e023941. http://dx.doi.org/10.1136/bmjopen-2018-023941.
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IntroductionConstipation is one of the most common gastrointestinal symptoms in postpartum mothers. The choice of treatments for postpartum constipation remains a challenging clinical problem. Chinese herbal medicine has become increasingly popular as an alternative therapy for constipation. This systematic review aims to evaluate the efficacy and safety of Chinese herbal medicine for postpartum constipation.Methods and analysisWe will search PubMed (1946 to present), EMBASE (1974 to present), Cochrane Central Register of Controlled Trials (all years), Web of Science (1900 to present), Chinese Biomedical Literatures Database (1978 to present), China National Knowledge Infrastructure (1979 to present) and WANFANG data (1998 to present) to identify any eligible study. No restriction will be put on the language, publication date or status of the study. The primary outcome will be the spontaneous bowel movement. Secondary outcomes will be stool consistency, quality of life, transit time, relief of constipation symptoms and adverse events. We will perform the meta-analysis when more than one trial examines the same intervention and outcomes with comparable methods in similar populations. If the heterogeneity is not significant statistically (p>0.10 or I2<50%), the fixed-effect model will be built to estimate the overall intervention effects. Otherwise, the random-effect model will be used to provide more conservative results.Ethics and disseminationNo ethical issues are foreseen because no primary data will be collected. The results will be published in a peer-reviewed scientific journal.PROSPERO registration numberCRD42018093741
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Deml, Michael J., Kristen Jafflin, Sonja Merten, et al. "Determinants of vaccine hesitancy in Switzerland: study protocol of a mixed-methods national research programme." BMJ Open 9, no. 11 (2019): e032218. http://dx.doi.org/10.1136/bmjopen-2019-032218.
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IntroductionVaccine hesitancy is a complex public health issue referring to concerns about the safety, efficacy or need for vaccination. Relatively little is known about vaccine hesitancy in Switzerland. This ongoing study (2017–2021) focuses on biomedical and complementary and alternative medicine (CAM) providers and their patients since healthcare professionals play important roles in vaccination decision-making. This national research programme seeks to assess the sociocultural determinants of vaccine hesitancy regarding childhood and human papillomavirus vaccines in Switzerland. We aim to provide a detailed characterisation of vaccine hesitancy, including CAM and biomedical perspectives, patient–provider interactions, and sociocultural factors, to establish the mediating effects of vaccine hesitancy on underimmunisation, and to design an intervention to improve vaccination communication and counselling among physicians, parents and adolescents.Methods and analysisOur transdisciplinary team employs a sequential exploratory mixed-methods study design. We have established a network of more than 150 medical providers across Switzerland, including more than 40 CAM practitioners. For the qualitative component, we conduct interviews with parents, youth, and biomedical and CAM providers and observations of vaccination consultations and school vaccination information sessions. For the quantitative component, a sample of 1350 parents of young children and 722 young adults (15–26 years) and their medical providers respond to questionnaires. We measure vaccine hesitancy with the Parent Attitudes about Childhood Vaccines 15-item survey and review vaccination certificates to assess vaccination status. We administer additional questions based on findings from qualitative research, addressing communication with medical providers, vaccine information sources and perceptions of risk control vis-à-vis vaccine-preventable diseases. The questionnaires capture sociodemographics, political views, religion and spirituality, and moral foundations.Ethics and disseminationThe study was approved by the local ethics committee. The results will be published in peer-reviewed journals and disseminated to healthcare professionals, researchers and the public via conferences and public presentations.
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Zaidi, Hasan A., Andrew J. Montoure, and Curtis A. Dickman. "Surgical and clinical efficacy of sacroiliac joint fusion: a systematic review of the literature." Journal of Neurosurgery: Spine 23, no. 1 (2015): 59–66. http://dx.doi.org/10.3171/2014.10.spine14516.
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OBJECT The sacroiliac joint (SIJ) and surgical intervention for treating SIJ pain or dysfunction has been a topic of much debate in recent years. There has been a resurgence in the implication of this joint as the pain generator for many patients experiencing low-back pain, and new surgical methods are gaining popularity within both the orthopedic and neurosurgical fields. There is no universally accepted gold standard for diagnosing or surgically treating SIJ pain. The authors systematically reviewed studies on SIJ fusion in the neurosurgical and orthopedic literature to investigate whether sufficient evidence exists to support its use. METHODS A literature search was performed using MEDLINE, Google Scholar, and OvidSP–Wolters Kluwer Health for all articles regarding SIJ fusion published from 2000 to 2014. Original, peer-reviewed, prospective or retrospective scientific papers with at least 2 patients were included in the study. Exclusion criteria included follow-up shorter than 1-year, nonsurgical treatment, inadequate clinical data as determined by 2 independent reviewers, non-English manuscripts, and nonhuman subjects. RESULTS A total of 16 peer-reviewed journal articles met the inclusion criteria: 5 consecutive case series, 8 retrospective studies, and 3 prospective cohort studies. A total of 430 patients were included, of whom 131 underwent open surgery and 299 underwent minimally invasive surgery (MIS) for SIJ fusion. The mean duration of follow-up was 60 months for open surgery and 21 months for MIS. SIJ degeneration/arthrosis was the most common pathology among patients undergoing surgical intervention (present in 257 patients [59.8%]), followed by SIJ dysfunction (79 [18.4%]), postpartum instability (31 [7.2%]), posttraumatic (28 [6.5%]), idiopathic (25 [5.8%]), pathological fractures (6 [1.4%]), and HLA-B27+/rheumatoid arthritis (4 [0.9%]). Radiographically confirmed fusion rates were 20%–90% for open surgery and 13%–100% for MIS. Rates of excellent satisfaction, determined by pain reduction, function, and quality of life, ranged from 18% to 100% with a mean of 54% in open surgical cases. For MIS patients, excellent outcome, judged by patients’ stated satisfaction with the surgery, ranged from 56% to 100% (mean 84%). The reoperation rate after open surgery ranged from 0% to 65% (mean 15%). Reoperation rate after MIS ranged from 0% to 17% (mean 6%). Major complication rates ranged from 5% to 20%, with 1 study that addressed safety reporting a 56% adverse event rate. CONCLUSIONS Surgical intervention for SIJ pain is beneficial in a subset of patients. However, with the difficulty in accurate diagnosis and evidence for the efficacy of SIJ fusion itself lacking, serious consideration of the cause of pain and alternative treatments should be given before performing the operation.