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Dissertations / Theses on the topic 'Alzheimer's disease – Patients – Family'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 January 2023

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1

Bizzell, Laurie. "Stressors, Resources, and Psychological Symptomatology for Family Caregivers of Alzheimer's Patients." Thesis, University of North Texas, 1993. https://digital.library.unt.edu/ark:/67531/metadc500551/.

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The purpose of this study was to examine the relationship between life stressors, resources, and psychological symptomatology of 20 family caregivers of Alzheimer's patients. Stressors were categorized as stressors specific to the caregiving role and general life stressors. Resources were also categorized as resources specific to the caregiving role and general life resources. Multiple regression determined which stressors, resources, and demographic variables predicted psychological symptomatology. Specific stressors that were significant predictors included: caregiving events, caregiving event chronicity, and mean burden scores. Significant general stressors included: size of caregivers' household, non-caregiving events and non-caregiving event chronicity. Significant resources included: other caregivers, the duties other caregivers provided, and caregiver's educational level. No Other Demographic Variables were found to be significant predictors.

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2

Reisler, Steven E. (Steven Elliot). "Coping strategies employed by in-home family caregivers of Alzheimer's patients." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35326.

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Most demented individuals are now cared for at home by family members. The present study examined the coping strategies employed by family caregivers, their perception of burden, and the internal dialogues employed by caregivers to stressful events. Sixteen (13 females, 3 males) participants with an average age of 67.4 years were interviewed. Results indicate that caregivers who spend less hours per week caring for their care receiver perceived less overall burden and caregivers who subjectively felt that they were coping with their role tended to use more coping strategies. Caregivers' internal dialogues and comments concerning problems coping with Alzheimer's patients are included.

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3

Driskill, Gail. "Effects of an Intervention Program on Caregiver Coping Efficacy." Thesis, University of North Texas, 1993. https://digital.library.unt.edu/ark:/67531/metadc500883/.

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The purpose of this study was to examine the effect of an intervention program for Alzheimer's patients on coping efficacy of their family caregivers. Using a pre-post repeated measures design, 16 family caregivers were interviewed before and after a medical, nursing, and social service intervention. Self-report measures, adjusted for caregiver satisfaction and caregiver mastery, were used to determine if there was a change in: resources, burden, and coping efficacy with caregiver specific and general life events. Results showed a marginal effect [F = 2.6, df(4,10), p<.10] for the omnibus MANCOVA. Most of this change was due to an increase in resources. Covariates of caregiver satisfaction and mastery were correlated with average burden. Results suggest that interventions such as this will be helpful for family caregivers of Alzheimer's patients.

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4

Straw, Lorraine B. "Impact of Alzheimer's disease on family caregivers : support group participation and other predictor variables /." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487585645578764.

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5

Warner, Judy A. "Perceptions of family caregivers of non-institutionalized Alzheimer's patients about support groups." Virtual Press, 1999. http://liblink.bsu.edu/uhtbin/catkey/1133742.

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The purpose of this descriptive study was to document and analyze the perceptions of family caregivers of non-institutionalized Alzheimer's patients about the benefits and limitations of Alzheimer's support groups. Survey methodology was used to survey caregivers and support group leaders from eight Alzheimer's support groups in the central Indiana area. Several of the major findings challenge the literature. These findings are as follows: The majority of caregivers attended the support group to receive information. None of the caregivers attended the support group due to frustration, and only one caregiver responded that relieving frustration was a benefit of participating in the support group. A majority of caregivers and support group leaders were positive about mixed (spouses and adult children) support groups. A majority of caregivers responded that they did not have guilt, anger, fears about caregiving in the future, or stress concerning their caregiving responsibilities. The study generated several implications that can be used by planners to improve support groups.
Department of Educational Leadership

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6

Tu, Su-Fen. "The Relationship Between Leisure and Perceived Burden of Spouse Caregivers of Persons with Alzheimer's Disease." Thesis, University of North Texas, 1993. https://digital.library.unt.edu/ark:/67531/metadc501255/.

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The problem of this study was to better understand spouse caregivers' leisure involvement, experience, and barriers and their relationships with perceived burden. Thirty-six wife and 19 husband caregivers of persons with Alzheimer's disease and related disorders volunteered to participate in this study, either by mailed questionnaire or interview. Respondents were primarily female, white, with an average age of 72 years. The conclusions of the study were: (a) caregivers significantly reduce both their leisure involvement; (b) self-reported health, perceived social supports, income level, use of paid help, and leisure activity patterns are major factors associated with caregivers' leisure; and (c) leisure barriers are a significant contributor to caregivers' perceived burden. Recommendations were presented for caregivers, practitioners, and future study.

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7

Zhao, Huan, and 赵环. "Living and loving: adaptive experiences of caregiving to a spouse with Alzheimer's disease in Shanghai, China." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48329599.

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This qualitative study is an attempt to explore the adaptive experiences of elderly Chinese caregivers who have to take care of their spousal partners who are suffering from Alzheimer’s disease (AD). As the illness is known to be chronic and degenerative in nature, caregivers are thus faced with many stressful situations and adjustments are necessary. The purpose of this study is to examine how these caregivers in AD situations are interpreting the factors that might have influenced their adjustments. The sample consists of 26 participants aged 60 and above that have been a primary caregiver for not less than a year. Three in-depth interviews were conducted with each participant during the study period, which lasted for about two years. Findings show that most of them had to adjust to stressful situations in various aspects of life. They also developed many strategies for life adaption, which can be summarized in the following six adjustment themes. First, after hearing the AD diagnosis, they initially experienced a series of shocks and false hopes, and subsequent adjustments include eliminating uncertainty, establishing reasonable expectations toward both the disease and treatment, learning to take on the caregiver role, and finally, separating the disease from their partner’s personality. Second, these elderly caregivers gradually learned to attain inner peace through converting to various religions, searching for meanings within their stressful situations, and reconstructing rational explanations for their negative emotions. Third, in the area of spousal interaction, adaptive strategies included staying connected with their sick partners, reinforcing their caregiving motivations, completing the “familiar-strange-familiar” cycle, and re-establishing daily routines. Fourth, in situations involving other family members, such as adult children, the adjustment strategies included sharing economic burdens, re-allocating housework chores, delegating care responsibilities, and emotionally supporting one another. Fifth, in terms of social network, the main support that caregivers received usually came from informal sources; formal support is extremely limited. Findings further show a connection between the input and output of social support and personal capacity. Sixth, elderly spousal caregivers often possessed the ability to re-position and re-construct their self-confidence while adjusting to their new life rhythm. They were also able to achieve a balance between their private lives and their care responsibilities, which helps to maintain their well-being and neutralize their distresses. In summary, participants of the study often utilized more than one strategy in adjusting to their situations. The six aspects of adjustments are thus put together in this study as an integrated model of life adaptation and survival tactics adopted by elderly Chinese AD spousal caregivers. Also, whether these caregivers are successful in adapting depends on their abilities to accept changes in themselves and their environment, and achieve a compromise between the two. Based on the above findings, a culturally sensitive perspective is thus put forward to enhance the understanding of studied phenomenon within the contemporary Chinese context. Recommendations are also made regarding the needed policy changes and the revisions of social work practices in support of the elderly suffering from AD and their caregiving spouses.
published_or_final_version
Social Work and Social Administration
Doctoral
Doctor of Philosophy

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8

Holt, Jim, Lynetta Stiltner, and Rick Wallace. "Do Patients at High Risk of Alzheimer’s Disease Benefit from Early Treatment?" Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etsu-works/6485.

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9

Holt, Jim, Lynetta Stiltner, and Rick L. Wallace. "Do Patients at High Risk of Alzheimer’s Disease Benefit from Early Treatment?" Digital Commons @ East Tennessee State University, 2009. https://dc.etsu.edu/etsu-works/6485.

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10

Anderson, Cristina L. (Cristina Lee). "Caregiver Personality as a Contributing Factor in Caregiver Burden." Thesis, University of North Texas, 1994. https://digital.library.unt.edu/ark:/67531/metadc500270/.

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Personality characteristics of spousal and adult children and active potential caregivers of persons with Alzheimer's Disease were studied in order to better predict caregiver burden and aspects of well-being. Contrary to prediction, no differences were found between spouse and adult children active caregivers on measures of well-being. Additionally, adult children potential caregivers indicated feeling less control over their lives than spouse potential caregivers. When social desirability was controlled, active caregivers reported greater fluctuations in affect than did potential caregivers. As predicted, personality characteristics of individuals were found to have the biggest role in determining which individuals experience stress or burden.

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11

Smith, Rebecca Ann. "Factors that influence decision-making for out-of-home placement of Alzheimer's disease patients by caregiver wives." CSUSB ScholarWorks, 1998. https://scholarworks.lib.csusb.edu/etd-project/1776.

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12

Achor, Sam Ndu. "Family visits or contact to dementia elderly at long term care facilities." CSUSB ScholarWorks, 2000. https://scholarworks.lib.csusb.edu/etd-project/1581.

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13

Fisher, Nancy Justina. "Neuropsychological subgroups of patients with Alzheimer's disease." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0012/NQ52421.pdf.

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14

Johnstone, Brian Robert. "Psychometric testing of patients with Alzheimer's disease." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239007.

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15

Holt, Jim. "Alzheimer’s Disease." Digital Commons @ East Tennessee State University, 2009. https://dc.etsu.edu/etsu-works/6482.

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16

Bondi, Mark William 1964. "Implicit and explicit memory in Alzheimer's disease and Parkinson's disease." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/276974.

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Several tasks examined implicit and explicit memory in matched samples of Alzheimer's (AD) and Parkinson's disease (PD) patients, and healthy elderly subjects. Lexical priming, pursuit-rotor tracking, and a fragmented pictures test, followed by explicit memory tests, were given. AD patients were impaired on all explicit tests and on lexical priming, but were intact on pursuit-rotor tracking and the procedural learning (PL) component of the fragmented pictures test. PD patients were significantly better than AD patients on all explicit memory tests, but were selectively impaired on the PL component of the fragmented pictures test. Finally, a mirror reading test was given to the PD patients and matched control subjects, with no significant differences in performance between the two groups demonstrated. Results are discussed in terms of hypothetical cognitive processes and brain circuits underlying different explicit and implicit memory domains.

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17

Freed, David Matthew. "Behaviorally defined subgroups of patients with Alzheimer's disease." Thesis, Massachusetts Institute of Technology, 1986. http://hdl.handle.net/1721.1/29515.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences, Technology, and Management, Dept. of Brain and Cognitive Sciences, 1986.
MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE
Bibliography: leaves 113-128.
by David Matthew Freed.
Ph.D.

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18

Vasseur, Janis S. "The geographical implications of Alzheimer's disease : an examination of the impact that Alzheimer's disease hs on family caregivers in Connecticut /." Abstract Full Text (PDF), 2008. http://eprints.ccsu.edu/archive/00000509/02/1965FT.pdf.

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Thesis (M.S.) -- Central Connecticut State University, 2008.
Thesis advisor: Cynthia Pope. "... in partial fulfillment of the requirements for the degree of Master of Science in Geography." Includes bibliographical references (leaves 85-90). Also available via the World Wide Web.

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19

Holt, Jim, J. Guduru, and S. Pathi. "Alzheimer’s Disease, 2nd Revision." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/6478.

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20

Holt, Jim, J. Guduru, M. Medipally, and S. Pathi. "Alzheimer’s Disease, 1st Revision." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/6480.

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21

Raffaniello, Lori A. "Level of Stress Among Family Caregivers of Alzheimer's Patients /." Staten Island, N.Y. : [s.n.], 1990. http://library.wagner.edu/theses/nursing/1990/thesis_nur_1990_raffa_level.pdf.

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22

Kixmiller, Jeffrey S. "Subtyping patients with Senile Dementia of the Alzheimer type using cluster analysis." Virtual Press, 1992. http://liblink.bsu.edu/uhtbin/catkey/833474.

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The purpose of this study was to determine if distinct subgroups of patients with Senile Dementia of the Alzheimer Type (SDAT) could be identified using seven scales of the Cognitive Behavior Rating Scale (CBRS). Ward's method of cluster analysis was used to group 104 patients with a probable diagnosis of SDAT into subtypes.The following three clusters were identified: (a) Moderately Impaired, (b) Severely Impaired, and (c) Emotionally Intact which displayed differences in symptom severity. Clusters could be partially defined by the amount of time they had been diagnosed with the disease. Differences in the cluster's configuration of scores had little/no descriptive utility. Subsequent discrimination analyses indicated that patient demographics were not as useful as the CBRS in classification of patients.This study provided evidence for the CBRS's ability to differentially portray SDAT patients' profiles. Results provide partial support for a stage model of SDAT. Implications of existing subgroups in SDAT are discussed as they pertain to patient management issues.
Department of Counseling Psychology and Guidance Services

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23

Holt, Jim, Christopher T. Bridges, and Christian B. Potter. "Dementia (Alzheimer’s Disease), 3rd Revision." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/6472.

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24

Chen, Lu-hua, and 陳璐華. "Evaluation of eIF-2α phosphorylation in patients with Alzheimer's disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B45011151.

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25

Goss, Mary J. "Stress and coping in carers of patients with Alzheimer's disease." Thesis, Queen's University Belfast, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359067.

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26

Davis, Nichole M. "The pattern of naming deficits in patients with Alzheimer's disease /." View abstract, 2000. http://library.ccsu.edu/ccsu%5Ftheses/showit.php3?id=1613.

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Thesis (M.A.)--Central Connecticut State University, 2000.
Thesis advisor: Charles Mate-Kole. " ... in partial fulfillment of the requirements for the degree of Master of Arts in Psychology." Includes bibliographical references (leaves 40-47).

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27

Erickson-Taube, Christina Marie. "Special care units: Recreational activities for patients with Alzheimer's disease." CSUSB ScholarWorks, 2005. https://scholarworks.lib.csusb.edu/etd-project/2843.

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The purpose of this study was to evaluate the recreational activities provided in special care units located in the Inland Empire. The population that this study sought to assist was patients diagnosed with Alzheimer's disease and living in an Alzheimer's special care unit.

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28

Torres, Janet Shin Yi. "GENDER DIFFERENCES IN CAREGIVER BURDEN AMONG ALZHEIMER'S PATIENTS." CSUSB ScholarWorks, 2018. https://scholarworks.lib.csusb.edu/etd/681.

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The purpose of this research was to explore the gender differences in caregiver burden in Alzheimer’s patients in the Inland Empire. Currently, there are more than half a million Californians who live with Alzheimer’s disease (Ross, Brennan, Nazareno, & Fox, 2009) and this number is expected to double over the next few years. Due to an increase in the older population and the rise of informal caregivers, the study provided insight as to how males and females perceive caregiver burden and how each gender responds to caregiver burden. This exploratory study utilized a quantitative research design through the use of questionnaires which measured caregiver burden through the use of the Zarit Burden Interview. A total of 38 participants were recruited through support groups at the Inland Caregiver Resource Center. Though findings did not suggest a gender difference in caregiver burden, they did indicate that there was a relationship between ethnicity and gender in relation to the caregiver and care receiver relationship. Implications for social work practice include assessment for and aid in the development of gender appropriate resources for informal caregivers of Alzheimer’s patients.

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29

Lineweaver, Tara T. "An investigation of visuospatial orientation and mental rotation in patients with Alzheimer's disease and patients with Huntington's disease /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1999. http://wwwlib.umi.com/cr/ucsd/fullcit?p9935484.

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30

Chen, Lu-hua. "Evaluation of eIF-2 alpha phosphorylation in patients with Alzheimer's disease /." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38284273.

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31

Cooper, Janine M. "Provoked confabulations distinguish patients with early Alzheimer's disease from normal elderly." Thesis, University of Aberdeen, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415599.

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The initial experiment used a new ABM questionnaire to test the ability of a group of 21 elderly adults and 20 patients with minimal to mild AD to retrieve personal episodic and semantic memories from across the life span. The test revealed that AD patients were significantly impaired compared to elderly adults on all aspects of the questionnaire compared to controls, especially for the retrieval of ‘true’ episodic memory, which was defined as uniquely detailed information that enables one to re-experience an event. There was a significant temporal gradient in retrieval of semantic memory but not for episodic memory. The results suggested that there was a dissociation between episodic and semantic ABM. The neural segregation of the episodic and semantic aspects of ABM was then explored using a paradigm based on the questionnaire during fMRI scanning. Twelve elderly and eleven young adults were tested. The results suggested that retrieval of the episodic aspect was linked to activation in the regions of the right frontal lobe, whereas retrieval of the semantic aspect was associated with activation of left frontal lobe areas. Elderly participants showed a decrease in activation of the right frontal lobe region during episodic retrieval compared to younger adults. The proposal that this area could be linked to autobiographical delusions was then explored. A new test that comprised of a discursive and a questionnaire section that could provoke confabulation revealed that AD patients made significantly more confabulations on both sections of the test than elderly adults. Through a series of experiments, it was found that the confabulation produced was not due to an overload in the memory capacity of AD patients or due to executive or attentional deficits. Rather it was found that the tendency to confabulate was linked to a deficit in the retrieval of the episodic aspect of ABM. Thus, the results from the experiments suggest that memory distortions in ABM in AD could be linked to a deficit in episodic memory and impaired reality monitoring, due to dysfunction of regions of the right frontal lobe.

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32

Burstein, Aaron, Imogene Grimes, Douglas Galasko, Paul Aisen, Marwan Sabbagh, and Adnan Mjalli. "Effect of TTP488 in patients with mild to moderate Alzheimer's disease." BioMed Central, 2014. http://hdl.handle.net/10150/610067.

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BACKGROUND:TTP488, an antagonist at the Receptor for Advanced Glycation End products, was evaluated as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD). A previous report describes decreased decline in ADAS-cog (delta=3.1, p=0.008 at 18 months, ANCOVA with multiple imputation), relative to placebo, following a 5mg/day dose of TTP488. Acute, reversible cognitive worsening was seen with a 20mg/day dose. The present study further evaluates the efficacy of TTP488 by subgroup analyses based on disease severity and concentration effect analysis.METHODS:399 patients were randomized to one of two oral TTP488 doses (60mg for 6 days followed by 20mg/day
15mg for 6 days followed by 5mg/day) or placebo for 18 months. Pre-specified primary analysis, using an ITT population, was on the ADAS-cog11. Secondary analyses included as a key secondary variable the Clinical Dementia Rating-Sum of Boxes (CDR-SB), and another secondary variable of the ADCS-ADL.RESULTS:On-treatment analysis demonstrated numerical differences favoring 5mg/day over placebo, with nominal significance at Month 18 (delta=2.7, p=0.03). Patients with mild AD, whether defined by MMSE or ADAS-cog, demonstrated significant differences favoring 5mg/day on ADAS-cog and trends on CDR-sb and ADCS-ADL at Month 18. TTP488 plasma concentrations of 7.6-16.8ng/mL were associated with a decreased decline in ADAS-cog over time compared to placebo. Worsening on the ADAS-cog relative to placebo was evident at 46.8-167.0ng/mL.CONCLUSIONS:Results of these analyses support further investigation of 5mg/day in future Phase 3 trials in patients with mild AD.

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33

Maalouf, Elizabeth W. "Assessment of the knowledge and attitudes of nurses caring for patients with Alzheimer's disease / by Elizabeth W. Maalouf." Access Digital Full Text version, 1995. http://pocketknowledge.tc.columbia.edu/home.php/bybib/11751095.

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Thesis (Ed.D.)--Teachers College, Columbia University, 1995.
Includes tables. Typescript; issued also on microfilm. Sponsor: Barbara Wallace. Dissertation Committee: Marie O'Toole. Includes bibliographical references (leaves 95-103).

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34

Moore, Anna Westbrook Bacon. "Eyeblink classical conditioning to an olfactory stimulus in older adults, patients with Alzheimer's disease and older adults at risk for Alzheimer's Disease /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2000. http://wwwlib.umi.com/cr/ucsd/fullcit?p9970690.

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35

Garrison, Lisa Rae. "The syntactic comprehension deficit observed in Alzheimer's patients using an object manipulation task." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27927.

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In the present study, the syntactic deficit of Alzheimer's patients was investigated, using an object manipulation task. Four case studies were presented, using data from test batteries devised by Caplan (pers. comm.) and the author. Subjects responded by acting out stimulus sentences presented in aural and written modes, using a set of small figurines. Responses were evaluated following criteria described by Caplan (1986, pers. comm.). Data from the four subjects were compared with each other, and with data obtained from a similar battery administered to aphasic patients. An impairment in the ability to interpret certain syntactic structures was found for all subjects, indicating that Alzheimer's patients do suffer from a syntactic comprehension deficit in the early stages of the disease. Several syntactic structures which caused errors in the responses of the Alzheimer's subjects, also caused errors for the aphasic patients, suggesting that the parsing model underlying the design of the stimuli, described by Caplan (in press) is a valid description of normal language function. Results of the present investigation are examined in relation to a model of syntactic comprehension suggested by Caplan (in press). Contradictions to hypotheses proposed are noted. The limitations and diagnostic use of the object manipulation test, are discussed.
Medicine, Faculty of
Audiology and Speech Sciences, School of
Graduate

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36

Keast, Shelley Claralyn. "Experiences of spouses caring for aggressive family members diagnosed with Alzheimer's disease." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0002/MQ32149.pdf.

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37

Hudson, John M. "Consciously and nonconsciously controlled uses of memory in patients with Alzheimer's disease." Thesis, University of Lincoln, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312895.

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38

Salinas, Maureen R. "Caregiver Burden and Depressive Symptoms in Hispanic Caregivers of Alzheimer's Disease Patients." Scholarship @ Claremont, 2016. http://scholarship.claremont.edu/scripps_theses/795.

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Caregiving for a close family member with Alzheimer’s disease is a stressful situation to be in, that often leads to high levels of caregiver burden and subsequent stress and depressive symptoms, and while there are numerous community and government resources available to caregivers, there are aspects of Hispanic cultures that may lead Hispanic caregivers to have higher levels of caregiver burden and depressive symptoms than White caregivers. 80 Hispanic caregivers and 80 White caregivers, with 40 males and 40 females within each group, will be recruited to participate in this study. Scales will be administered to both Hispanic and White caregivers in order to assess levels of caregiver burden, depressive symptoms, familism values, gender role beliefs, acculturation levels, and knowledge, comfort, and use of community resources. Hispanic caregivers will have higher levels of caregiver burden and depressive symptom scores than White caregivers, while women will have higher scores overall than men overall. Hispanic caregivers will have less knowledge, comfort, and use of community resources than White caregivers, while gender role views, familism values, and acculturation levels will be mediating factors of these relationships. Cultural differences in caregiver burden need to be assessed further, so that clinical and practical implications for community and government resources can be discussed.

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39

Patni, Varuska, and Varuska Patni. "Transcranial Ultrasound as Therapy for Patients with Alzheimer's Disease and Other Dementias." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/625117.

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Alzheimer's disease is a progressive disorder that can affect cognitive and mental functions, and is the most common form of dementia. In upcoming years, the number of people expected to get Alzheimer's disease is expected to increase significantly due to so-called 'baby boomers' reaching advanced age. Clinical trials regarding dementia are critical in advancing Alzheimer's therapy, but drugs have been ineffective thus far. Rather than drugs, non-invasive brain stimulation techniques have had encouraging results. In animals, low to moderate transcranial ultrasound ('TUS') improves memory, and in humans, TUS causes improvements in mood. The application of TUS in humans is a promising therapy for neuronal growth, cognitive function, and mental state of mind. This paper reviews potential use of TUS for Alzheimer’s disease and dementia.

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40

Wisneski, Jennifer Lynne. "Social Support, Gender, and Burden in Caregivers of Patients with Alzheimer's Disease." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/4898.

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There are 15.9 million adults in the United States providing care to a family member diagnosed with Alzheimer's disease. Family member caregivers experience detrimental physical and mental health stress because of their caregiving role. The purpose of this study was to determine if the independent variables of marital status, perceived social support, and gender of family member caregivers of patients with Alzheimer's disease were related to the dependent variable of caregiver burden. The variables were examined through the lens of John Bowlby's attachment theory using archival data (n = 586) from the REACH II program. The results of the analysis of variance indicated that marital status did not affect level of burden. The outcome of a correlational analysis indicated a positive linear association between burden and social support. The result of an independent samples t test was that females reported higher burden than males. The outcome of a linear regression identified marital status, social support, and gender as predictors of caregiver burden. Positive social change implications of this study include contributing to scholarly literature, providing information for families to consider when implementing a plan for long-term care, and encouraging caregivers to seek professional support to minimize burden and maximize quality of life for themselves and the care receiver. Female caregivers with many social supports were identified as high risk for severe burden, an important factor for clinicians, agencies, and healthcare providers who work with family caregivers to consider. Identifying factors that contribute to burden and developing strategies to manage these factors may reduce severity of burden and improve quality of life for both caregivers and care recipients.

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41

Duncan, Marie Theresa. "Alzheimer's Disease Caregivers: The Transition from Home Care to Formal Care." PDXScholar, 1992. https://pdxscholar.library.pdx.edu/open_access_etds/3228.

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When family members no longer have the capacity to meet Alzheimer's Disease (AD) caregiving demands at home, a move to a nursing home or other formal care facility becomes the only solution. Recognizing this as a time of transition, three research questions were identified: (1) What do family caregivers to AD individuals experience as they shift their caregiving from home to formal care settings? (2) How does caregiving in formal care differ from caregiving at home? and (3) How do family caregivers perceive the relationships that develop between families and formal care staff? Specific attention was paid to the experiences of spouses and adult children. Using a qualitative approach, two specific bodies of data were investigated. First, transcripts of a series of 30 focus groups with 179 caregivers, and second, ten follow-up interviews were analyzed. Both spouses and adult children overwhelmingly identified physical exhaustion and often emotional exhaustion as the pervasive common experience. After reaching this state, caregivers identified the pivotal nature of events in contributing to placement. These kinds of events turn out to be more like turning points than crises. Caregivers in this study identified five themes that were influential in their decision-making process. In order of their importance to the caregivers, they were: events, the health care system, caregiver-care receiver relationship, support, and options and availability. A male spouse caregiver was likely to cite a turning point event centered on an incontinence problem, while for a female spouse caregiver, it was an AD safety issue. The health care system was usually a negative influence and served to delay the placement decision. Immediately, after placement, family caregivers noted shifts in control, involvement and personal reorganization. Family caregivers frequently noted the development of a caregiving relationship with staff. The individuals whom the family caregivers mentioned most often were the aides. Their bottom line was that staff deliver quality care, which they equated with caring about the resident rather than only taking care of them. The findings from this study have implications for theory development, family caregivers, formal care staff, and health care policy.

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42

Razani, Laleh Jill. "Semantic memory for olfaction and vision in patients with Alzheimers's disease, Huntington's disease, and normal individuals /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p9904729.

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43

Speice, Jenny. "The effects of family communication patterns during the middle phase of Alzheimer's disease." Diss., Virginia Tech, 1995. http://hdl.handle.net/10919/37763.

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44

Rochon, Elizabeth. "The nature and determinants of sentence comprehension impairments in patients with Alzheimer's disease." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=39439.

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This thesis investigated sentence comprehension impairments in patients with dementia of the Alzheimer's-type (DAT). The first three experiments investigated the nature of the impairments using different tasks. Across tasks, patients' performance by syntactic complexity, but was poorer for sentences that had more propositions. Results are discussed in terms of a post-interpretive processing impairment in these patients. Two additional experiments investigated possible determinants of sentence comprehension impairments in DAT. One employed a dual-task paradigm to examine the effect of increasing the processing load associated with sentence comprehension. The other examined processing resource limitations in the patients tested in the first and second experiments by employing a battery of tasks designed to measure all aspects of working memory. In both experiments, evidence for processing resource limitations was seen in impaired performance on a concurrent task in dual-task conditions. Results of the fifth experiment also provided evidence that DAT patients' sentence comprehension impairments are correlated with processing resource limitations.

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Forbes, Katrina Elaine. "A cognitive study of spontaneous speech and writing in patients with Alzheimer's disease." Thesis, University of Aberdeen, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395070.

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Although most neuropsychological studies have focused upon the memory breakdown suffered by Alzheimer's Disease (AD) patients, recent research suggests that language, especially semantics, is a promising area to identify deficits in AD. No specific language tests, however, have been developed to assess language in AD, and much research is flawed by the absence of longitudinal assessment, the inclusion of a complex task and a failure to differentiate patients in terms of severity. It is, therefore, extremely difficult to identify the impairments characteristic of each disease stage, and almost impossible to isolate those evident in the earliest stages. The main aim of this thesis was to develop a standardised instrument comprising a simple and complex component, which can assess the spontaneous speech and writing of AD patients over time and to document the longitudinal pattern of speech and writing deterioration suffered by such patients. Results from a series of experiments indicated that the task had high inter-rater, test-re-test and parallel forms reliability, was sensitive to the impairments suffered by the mildest of AD patients, whilst also being a valid measure of language impairments. A cross sectional and longitudinal assessment indicated that speech and writing follow a logical progression as AD advances, with initial breakdown in lexical processing and a subsequent breakdown in syntactic, phonological and visuo-special skills. Although a number of patients did show impairments in articulation and melodic line, the motoric aspects of speech remain relatively preserved. Despite the preservation of motor functions in speech, patterns demonstrate a pattern of peripheral dysgraphia that is characterised by a progressive shift in writing style, and problems forming and selecting letters. Although a complex task was necessary to identify such impairments in the early stages of AD, a simple one was sufficient to identify those in the latter stages. In contrast to the proposal that AD is simply a result of exaggerated ageing, qualitative and quantitative differences were evidence between healthy elderly individuals and the mildest of AD patients. Indeed it seems that the pattern of language impairments shown by AD patients, arise as a result of cortical degeneration, which is centred in the temporal and parietal lobes, areas which are involved in the phonological and semantic aspects of language production.

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Norton, Lauren E. "Performance on perceptual-structural priming tasks in patients with probable Alzheimer's Disease (AD) /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p9907594.

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FOX, MARY VYN. "SOCIAL SUPPORT AND PSYCHOLOGICAL DISTRESS AMONG SPOUSE CAREGIVERS OF DEMENTIA PATIENTS (ALZHEIMER'S DISEASE)." Diss., The University of Arizona, 1986. http://hdl.handle.net/10150/188184.

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This study is an examination of the informal support systems of 40 spouse caregivers of dementia patients in relation to two variables associated with maintaining their patient at home: (1) the caregiver's experience of psychological distress, and (2) the caregiver's need for formal support. There now exists evidence to suggest that informal supports act to mediate the stress associated with caring for a dementia patient; however, research in the area of social supports has generally lacked careful definitions of the variables at work. To remedy that deficiency, distinctions were made in this study between the quantitative and qualitative dimensions of informal supports and the expressive and instrumental functions of informal supports. Initial analyses did not support the hypotheses that informal supports operate independently to buffer caregivers' experience of psychological distress and the need for formal support. However, when formal support was redefined in terms of two types of services--professional counseling services and community services--significant findings did emerge. Level of caregiver anxiety was found to be significantly related to perceived need for counseling services. Perceived need for community services was predicted by the combination of the patient's level of cognitive impairment, and the caregiver's experience of higher levels of anxiety and lower levels of informal expressive support. These results suggest that interventions directed toward the provision of services should be based on a thorough evaluation which includes the patient's level of functioning as well as the caregiver's emotional and instrumental resources. Professionals working with dementia patients and their families must be alerted to those caregivers who are at risk of severe emotional distress, and services should be provided to them before families collapse under the strain of caregiving.

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Dolan, Mary L. "Living with Alzheimer's Disease: An Examination of Caregiver Coping Mechanisms." Ohio University Honors Tutorial College / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1276009587.

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Tomaszewski, Sarah. "The Relationship Between Neuropsychological Performance and Daily Functioning in Individuals with Alzheimer's Disease." Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2494/.

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The results of neuropsychological tests are often used by clinicians to make important decisions regarding a demented patient's ability to competently and/or independently perform activities of daily living. However, the ecological validity of most neuropsychological instruments has yet to be adequately established. The current study examined the relationship between neuropsychological test performance and functional status in 42 individuals diagnosed with Alzheimer's Disease. A comprehensive battery of cognitive tests was employed in order to assess a wide range of neuropsychological abilities. Functional status was measured through the use of both a performance-based scale of activities of daily living (The Direct Assessment of Functional Status; Loewenstein et al., 1989) as well as by a caregiver/informant-based rating scale (Instrumental Activities of Daily Living; Lawton & Brody, 1969). Findings suggest that neuropsychological functioning is moderately predictive of functional status. Memory performance was the best predictor of functional status in most ADL domains, followed by executive functioning and visuospatial abilities.

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Toney, Sharlene. "Factors influencing surrogate end-of-life healthcare decision-making for a family member with Alzheimer's disease." unrestricted, 2006. http://etd.gsu.edu/theses/available/etd-12152006-151721/.

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Thesis (Ph. D.)--Georgia State University, 2006.
Title from title screen. Cecelia G. Grindel, committee chair; Laura P. Kimble, Frank Whittington, Carolyn Kee, committee members. Electronic text (220 p. : ill.). Description based on contents viewed May 2, 2007. Includes bibliographical references (p. 114-136).

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