Academic literature on the topic 'Amazon Kinesis'

This chapter delves into the application integration services offered by AWS, which proves particularly beneficial for microservices, distributed systems, and serverless applications. These services facilitate seamless communication between loosely related components. The chapter provides an overview of various AWS integration services, emphasizing their importance in integration processes. Key topics covered in this chapter include SQS (Simple Queue Service), SNS (Simple Notification Service), Kinesis, Pinpoint, and Amazon MQ. Furthermore, the chapter offers practical guidance through hands-on illustrations focused on SQS, allowing readers to gain valuable experience in utilizing these services. By exploring these AWS application integration services, readers can enhance the efficiency and effectiveness of their integration processes. This chapter serves as a comprehensive guide for understanding and utilizing services like SQS, SNS, Kinesis, Pinpoint, and Amazon MQ, enabling seamless communication and integration within AWS environments.

The material's exciting properties, which have substantially expanded the field of study, include its enormous surface area, outstanding electrical conductivity, extreme thinness, amazing electron kinesis, and cutting-edge mechanical control. These topographies are largely active for various energy-storage devices (EESDs) such as supercapacitors, hybrid cathode and anode materials, lithium-sulfur batteries, lithiumion batteries, lithium-oxygen batteries, and sodium-ion batteries. The scalability, stability, and uniformity of nanomaterials made of carbon are essential for the development of graphene-based energy storage devices.

Stimulating properties of two 2D-Graphene, like its huge surface area, exceptional electrical conductivity, extreme thinness, amazing electron kinesis, and state-of-the-art mechanical regulation, have added an enormous investigative concern. This background exhibits significant dynamism and find widespread application in various energy storage devices like Li-sulfur batteries, Li-ion batteries, Li-oxygen batteries, sodium Ion batteries and also as a hybrid cathode/anode material for supercapacitors. Scaled-up, stable production and correspondence of carbon-based nano-materials are essential conditions for the preparation of graphene-based EESDs. This chapter diagnostically explains the synthesis methods of graphene and the properties of graphene-nanomaterials with various dimensions in adaptable EESDs. The main tasks and scenarios in this field are also discussed.

The distinctions between what has previously been termed cell therapy and gene therapy have become blurred. Cell therapy traditionally implied the in vitro expansion of cells that could subsequently be engrafted into patients to elicit a therapeutic effect, while gene therapy was a term applied to the genetic manipulation of tissues or cells in vivo or ex vivo. With the amazing advances that have been achieved using transcription factors to reprogramme cells, this distinction, at least for regenerative medicine applications, no longer exists. In this chapter, following the statement of the unmet clinical need, we review potential sources of new β‎ cells and approaches to β‎ cell replacement therapy; discuss how recent advances in safety and efficacy of gene transfer technology can augment cellular therapeutic approaches, and summarize pure gene therapy approaches dependent on expression of genes encoding insulin and other glucose-lowering hormones in the recipient’s own cells. Since both type 1 and type 2 diabetes are associated with a decline in β‎ cell mass, cell and gene therapy targeted at the β‎ cell and insulin replacement have potential applications for both forms of the disease. In type 1 diabetes, uninterrupted compliance with insulin injection therapy is necessary to prevent potentially fatal ketoacidosis. The landmark Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications follow-up study have confirmed that chronic hyperglycaemic microvascular and macrovascular complications can be prevented by tight glycaemic control, but this was at the expense of a threefold increase in severe hypoglycaemia—one of the greatest fears of those living with daily insulin injections. Overall, the health implications and economic costs of type 1 diabetes are massive, and increasing annually. There is, therefore, an unquestionable clinical need for new therapeutic options. While transplantation of whole pancreas together with its blood supply can entirely normalize blood glucose levels, the major surgery required is associated with 5% mortality in the first year, even in the most experienced centres. Isolation and transplantation of purified insulin-secreting islets of Langerhans from a donor pancreas requires only minimally invasive cannulation of the portal vein transhepatically under X-ray guidance. This offers the promise of more widespread implementation restoring excellent control, preventing both long-term complications and severe hypoglycaemia. Capacity will, however, be severely limited by the scarcity of deceased donor organs: currently sufficient for fewer than 1% of those who might benefit from this form of treatment. This has provided impetus to efforts to produce a replenishable supply of glucose-responsive insulin-secreting cells that could be used in transplantation. One potential source might involve the in vitro differentiation of stem cells derived from embryonic and adult tissue. Type 2 diabetes is marked by both a resistance of target tissue to the effects of insulin and impaired function of the β‎ cell. The major β‎-cell defects relate to an impaired secretory response to glucose, altered kinetics of secretion including pulsatility, accumulation of islet amyloid polypeptide, an increase in glucagon-secreting α‎ cells, and a decline in β‎-cell mass. Current therapy for type 2 diabetes involves a combination of drugs directed at improvements in both insulin sensitivity and β‎-cell function, together with management of associated cardiovascular risk factors. Conventional treatment modalities have not been able to prevent the inexorable progressive loss of β‎-cell function necessitating insulin replacement in the majority over time, but this is often insufficient to sustainably achieve target glucose levels outwith intensive clinical trials. It is envisaged that novel cell therapy approaches will enable restoration of β‎-cell mass.

Abstract Low alloy ferritic steels used in fabricating cost-effective cylinders for hydrogen storage are susceptible to hydrogen embrittlement. A model first proposed by Amaro et al. (ARFiDS model) for predicting the effects of hydrogen pressure on the kinetics of hydrogen assisted fatigue crack growth (HA-FCG) in X-100 pipeline steels for pressure between 1 and 20 MPa is adapted in this study and used for predicting the HA-FCG behavior of SA372 Grade J Class 70 pressure vessel steels for pressures ranging between 10 and 102 MPa. The crack growth kinetics in these steels exhibit a typical two-