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Dissertations / Theses on the topic 'Amide cinnamic acid derivatives'

Author: Grafiati

Published: 24 April 2022

Last updated: 30 July 2025

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1

McNichols, Brett William. "Synthesis and Application of Styryl Phosphonic and Cinnamic Acid Derivatives." Thesis, Colorado School of Mines, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10624231.

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<p> Styryl phosphonic and cinnamic acid derivatives have been gaining attention as key candidates to modulate specific electrode properties in organic electronic devices such as work function, surface energies, wettability, and electron charge transfer kinetics that lead to increased efficiency, operational range, and device lifetimes. Very few of these acids are commercially available. The driving factor behind this research is to explore simple, high yield, and inexpensive synthetic routes towards synthesis of these acids. Herein, the novel synthesis of vinyl phosphonic acids (VPAs) and thei

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2

Nguyen, Dao. "SYNTHESIS OF A NOVEL FAMILY OF AMIDE DERIVATIVES OF PODOCARPIC ACID." Master's thesis, University of Central Florida, 2004. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2221.

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As a class, amides are of great interest in biological studies and pharmaceutical application. In this work, podocarpic acid, a natural tricyclic diterpene, derived from Podocarpus species, has been employed to form a novel family of amide derivatives which will later be studied for their potential as new drug leads. Novel amide derivatives of podocarpic acid were synthesized from podocarpic acid in three steps. The first step involved methylation with dimethylsulfate to form methyl-O-methylpodocarpate. This step was followed by iodination with iodine to give iodomethyl-O-methylpodocarpate. Fi

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3

Koch, Horst, André Laschewsky, Helmut Ringsdorf, and Kang Teng. "Photodimerization and photopolymerization of amphiphilic cinnamic acid derivatives in oriented monolayers, vesicles and solution." Universität Potsdam, 1986. http://opus.kobv.de/ubp/volltexte/2008/1711/.

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Cinnamic acid moieties were incorporated into amphiphilic compounds containing one and two alkyl chains. These lipid-like compounds with photoreactive units undergo self-organization to form monolayers at the gas-water interface and bilayer structures (vesicles) in aqueous solutions. The photoreaction of the cinnamic acid moiety induced by 254 nm UV light was investigated in the crystalline state, in monolayers, in vesicles and in solution in organic solvents. The single-chain amphiphiles undergo dimerization to yield photoproducts with twice the molecular weight of the corresponding monomers

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4

Gregar, Travis Quinton. "Synthesis and structural characterization of amide-linked derivatives of N-acetyl neuraminic acid." Diss., The University of Arizona, 2001. http://hdl.handle.net/10150/279827.

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Amide linked carbohydrates represent a tremendously different type of compound. Sugars have traditionally been linked together as either N or O linked via the anomeric carbon to make larger compounds, i.e. Sialyl Lewis X. This linkage leads to great instability under acidic and biological conditions. N-Acetyl neuraminic acid is a naturally occurring delta peptide. Colominic acid is the naturally occurring O linked polymer of N-acetyl neuraminic acid. This polymer has been found to possess a helical structure starting at the hexamer length. Changing from an O linkage to an amide linkage provid

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5

Theddu, Naresh. "APPLICATIONS OF ENANTIOPURE SULFINIMINE DERIVED CHIRAL AMINE BUILDING BLOCKS FOR THE ASYMMETRIC SYNTHESIS OF TROPANE ALKALOIDS AND CYCLIC CIS BETA-AMINO ACID DERIVATIVES." Diss., Temple University Libraries, 2011. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/157444.

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Chemistry<br>Ph.D.<br>Chiral amines are ubiquitous in natural products and are found in many drugs and drug candidates. Enantiopure sulfinimines [RS(O)N=CHR1] are useful chiral building blocks for the stereoselective synthesis of amines and amine derivatives. The aim of this thesis research is to develop new methods to access chiral amine building blocks for applications in the synthesis of nitrogen-heterocycles including ring-substituted tropinones, tropanes, cyclic cis-beta-amino acid derivatives, and amino-cyclopentitols.<br>Temple University--Theses

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6

fadhil, ali abd al-karim alkarim. "Reversed-phase and surfactant modified reversed-phase high and ultra-high performance liquid chromatography of phenolic and aliphatic carboxylic acids." Miami University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1574428923192499.

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7

Leblanc, Jean-Pierre. "Synthese et caracterisation de polycondensats renfermant des motifs stilbeniques." Paris 6, 1988. http://www.theses.fr/1988PA066350.

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Polycondensation de l'acide trans stilbenedicarboxylique-4,4' (soa) avec des alpha ,omega -diamino alcanes et des alpha ,omega -diamino oligoethers. Etude de l'incorporation du soa dans des copolyarylates comme le poly(isophtalate de methyl phenylene) en vue d'obtenir des polymeres cristaux liquides, et des polyesters obtenus a partir d'autres monomeres (acide terephtalique). Amelioration des proprietes mecaniques des polycondensats par incorporation d'unites stilbeniques et d'acide p-acetoxybenzoique

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8

吳重孚. "Synthesis of Substituted Cinnamic Acid Amide Analogs." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/02394926598808616432.

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碩士<br>台北醫學大學<br>藥學研究所<br>83<br>A series of the cinnamic acid esters analogs had been reported in our lab. and the most potent compound was found to be 1,3-dicaffeoylpropandiol 11. The result obtained from previous investigation illustrated that the hydroxy group remained in the structure will be more efficient in platelet aggregation inhibitory activity. Since esters were considered to be relatively unstable compounds, synthesis of amide analogs were attempted. The substituted cinnamic acid derivatives including pcoumaric acid, ferulic acid, caffeic acid and p-methoxycinnamic acid, we

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9

Lee, Chia-hsiu, and 李嘉修. "Enzymatic synthesis of Cinnamic Acid Derivatives." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/24397101373491962989.

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碩士<br>國立臺灣科技大學<br>化學工程系<br>93<br>Ferulic acid (4-hydroxy 3-methoxy cinnamic acid), which occurred naturally in many plants, has been shown to possess photoprotective, antioxidant, antitumor and hypertensive activities. Octyl methoxycinnamate (OMC) is the most widely used non-allergic sunscreen agent in the market. Most literatures reported low conversion and long reaction time in the syntheses of ethyl ferulate and OMC. In his study, Novozym 435 was selected as the catalyst for the syntheses of ethyl ferulate from ferulic acid and ethanol, and OMC from 4-methoxycinnamic acid and 2-ethyl hex

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10

Chou, Shan-Yi, and 周珊沂. "Antifungal Activity of Cinnamic Acid Derivatives." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/83506275868488364942.

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碩士<br>國立臺灣大學<br>森林環境暨資源學研究所<br>103<br>Cinnamon contains many aromatic compounds, among these compounds, trans-cinnamaldehyde has been proven to possess many bioactivities, and which belongs to trans-cinnamic acid derivatives in the biosynthesis pathway. The objective of this research is to find more cinnamic acid dervitaves to against plant pathogenic fungi, wood rotting fungi and mildew, expecting to reduce the damage from fungi diseases. In order to evaluate antifungal activities of cinnamaldehyde congeners, we classified them into three groups, cinnamic acid congeners, cinnamaldehyde congen

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11

Dias, Ana Luísa de Sousa e. Castro. "Evaluation of the anticancer activity of cinnamic acid derivatives targeting COX-2." Master's thesis, 2021. https://hdl.handle.net/10216/138473.

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12

Gomes, Joana Rodrigues da Silva. "Hybrids of Flavonoids and Cinnamic Acid Derivatives Combining Photoprotection and Antioxidant Activity." Master's thesis, 2021. https://hdl.handle.net/10216/137031.

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13

Telmesani, Reem. "Development of flow methodologies for the [2+2] photocycloaddition of cinnamic acid derivatives and biological exploration of truxinic acid derived scaffolds." Thesis, 2018. https://hdl.handle.net/2144/34788.

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Cinnamic acids and their derivatives are building blocks for cyclobutanes in many natural products. In nature, dimerization of these derivatives is thought to occur through a [2+2] photocycloaddition. Experimentally, efficient dimerization of these substrates using UV irradiation has predominantly been achieved in the solid state and is thought to be a result of stringent requirements for distance and orientation of the participating olefins. In the following pages a new strategy is presented which achieves [2+2] dimerization of these substrates in solution through the use of a bis-thiourea ca

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14

Lee, Fu-Wei, and 李馥葳. "The structure-activity relationship of cinnamic acid derivatives on reactive oxygen species scavenging and xanthine oxidase inhibitory activities." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/49468018915766371013.

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15

Tsai, Chiung-Man, and 蔡瓊滿. "Assessment of the Anti-invasion Potential and Mechanism of Select Cinnamic Acid Derivatives on Human Lung Adenocarcinoma Cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/30158564578255666199.

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博士<br>中山醫學大學<br>醫學研究所<br>102<br>Patients with lung adenocarcinoma are often diagnosed with metastasizing symptom and die of early and distal metastasis. Metastasis is made up of a cascade of interrelated and sequential steps, including cell adhesion, extracellular matrix degradation, cell movement, and invasion. Hence, substances carry the ability against one of the metastasis-associated steps could be a potential candidate for preventing tumor cells from metastasizing and prolonging life of cancer patients. Cinnamic acid (CA) was demonstrated to be such a candidate for human lung adenocarcino

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16

Yang, John. "Pharmacokinetics and cytoprotective evaluation of Caffeic Acid Phenethyl Amide and fluorinated derivatives against oxidative stress." 2012. http://hdl.handle.net/2152/19620.

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Ischemic injury occurs when the flow of blood is reduced or blocked to an area of the body and can cause significant tissue damage by generation of reactive oxygen species (ROS), activation of apoptotic pathways and through induction of the inflammatory response. Restoration of blood flow and reperfusion of the blocked site, while essential, can generate a second injury that itself needs to be controlled. Together the two injuries are termed ischemia/reperfusion (I/R) injury. This type of injury is frequently encountered in medicine and is a major medical problem. Therapeutic strategies to com

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17

Gregorelli, Alex. "CHAPTER 1: ANTI-INFLAMMATORY ACTION OF ARACHIDONOYL AMIDE DERIVATIVES IN A HUMAN KERATINOCYTES CELL LINE MODEL OF ACUTE INFLAMMATION. CHAPTER 2: THE POLYPHENILPROPANOID VERBASCOSIDE INDUCES AUTOPHAGY IN HUMAN HEPATOCYTES CELL LINE BY AKT MODULATION." Doctoral thesis, 2015. http://hdl.handle.net/11562/915591.

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CHAPTER 1 L'acido arachidonico (AA) è un acido grasso poli-insaturo presente nei fosfolipidi di membrana. Esso viene rilasciato nel citosol delle cellule ad opera della fosfolipasi A2. L’AA è il substrato per le cicloossigenasi-1 e 2 che portano alla produzione di prostaglandine e prostacicline, noti mediatori dell’infiammazione. Tuttavia in letteratura la somministrazione di AA non ha sempre attività pro-infiammatoria, infatti, alcuni articoli riportano uno suo specifico effetto anti-infiammatorio (Adam Olaf., 2002). Una linea cellulare di cheratinociti umani in coltura (HaCaT), è stata attiv

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