Academic literature on the topic 'Amide function'

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Journal articles on the topic "Amide function"

1

Asahara, Haruyasu, Keita Arikiyo, and Nagatoshi Nishiwaki. "Development of variously functionalized nitrile oxides." Beilstein Journal of Organic Chemistry 11 (July 23, 2015): 1241–45. http://dx.doi.org/10.3762/bjoc.11.138.

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N-Methylated amides (N,4-dimethylbenzamide and N-methylcyclohexanecarboxamide) were systematically subjected to chemical transformations, namely, N-tosylation followed by nucleophilic substitution. The amide function was converted to the corresponding carboxylic acid, esters, amides, aldehyde, and ketone upon treatment with hydroxide, alkoxide, amine, diisobutylaluminium hydride and Grignard reagent, respectively. In these transformations, N-methyl-N-tosylcarboxamides behave like a Weinreb amide. Similarly, N-methyl-5-phenylisoxazole-3-carboxamide was converted into 3-functionalized isoxazole
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2

ZHANG, JIA-XIANG, LEI-YANG ZHANG, NAI-XING WANG, YUE-HUA WU, ZHAN YAN, and DUMITRA LUCAN. "NMR studies of rotamers with multi-substituted amides." Journal of Engineering Sciences and Innovation 6, no. 4 (2021): 373–80. http://dx.doi.org/10.56958/jesi.2021.6.4.2.

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Rotamers existed in the multi-substituted amide play an important role in the chemical reactivity function. Diverse chemical reactivity of substrates which contain an amide group is significantly affected by their rotamers. In this paper, rotamers of amides were studied and confirmed by means of NMR spectra. It was found that the ratio of related rotamers of amides depend on the amides bulk. When the nitrogen atom is located in the ring rigid structure, the rotation of C-N bond is limited and it is difficult to produce rotational isomers. In addition, we also found that substituted groups in p
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3

Zhou, Xueer, Petra Vasko, Jamie Hicks, et al. "Cooperative N–H bond activation by amido-Ge(ii) cations." Dalton Transactions 49, no. 27 (2020): 9495–504. http://dx.doi.org/10.1039/d0dt01960g.

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Germylium-ylidene cations, [R(L)Ge]<sup>+</sup>, featuring amido substituents at R and NHC or phosphine donors at L have been synthesized and structurally characterized. The Lewis acidic germanium cation and proximal amide function allow for facile cleavage of N–H bonds in 1,2 fashion.
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4

Zhang, Bengang, Xinyi Chen, Antonio Pizzi, et al. "Highly Branched Tannin-Tris(2-aminoethyl)amine-Urea Wood Adhesives." Polymers 15, no. 4 (2023): 890. http://dx.doi.org/10.3390/polym15040890.

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Condensed tannin copolymerized with hyperbranched tris(2-aminoethyl)amine-urea formed by amine-amido deamination yields a particleboard thermosetting adhesive without any aldehydes satisfying the requirements of relevant standards for the particleboard internal bond strength. The tannin–triamine–urea cures well at 180 °C, a relatively low temperature for today’s particleboard hot pressing. As aldehydes were not used, the formaldehyde emission was found to be zero, not even in traces due to the heating of wood. The effect is ascribed to the presence of many reactive sites, such as amide, amino,
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5

Sun, Chang-Liang, Xiao-Nan Jiang, and Chang-Sheng Wang. "An analytic potential energy function for the amide-amide and amide-water intermolecular hydrogen bonds in peptides." Journal of Computational Chemistry 30, no. 15 (2009): 2567–75. http://dx.doi.org/10.1002/jcc.21266.

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6

Pandita, Sangeeta, and Rohit Ishpujani. "AN ENVIRONMENTALLY FRIENDLY, EFFICIENT, AND FACILE METHODOLOGY FOR THE NITRATION OF AROMATIC COMPOUNDS USING UREA NITRATE." RASAYAN Journal of Chemistry 15, no. 04 (2022): 2933–37. http://dx.doi.org/10.31788/rjc.2022.1548002.

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An efficient, environmentally friendly, and facile methodology is developed for room temperature nitration of variously substituted aromatic compounds using urea nitrate and concentrated sulphuric acid. The method uses a simple aqueous workup without organic solvents and results in the formation of mono-nitro compounds in excellent yields. Amides are nitrated smoothly without hydrolysis of the amide function.
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7

Imhof, Wolfgang. "N-Phenyl-2-(phenyliminomethyl)pyrrole-1-carboxamide." Acta Crystallographica Section E Structure Reports Online 63, no. 11 (2007): o4265. http://dx.doi.org/10.1107/s1600536807048416.

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The title compound, C18H15N3O, was prepared from phenyl(1H-pyrrol-2-ylmethylene)amine and phenyl isocyanate in the presence of catalytic amounts of [Pd(PPh3)4]. The conformation of the molecular structure is determined by an intramolecular hydrogen bond between the amide NH function and the imine N atom. The molecule is essentially planar. Only the peripheral phenyl substitutents are bent out of the plane.
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8

McKinney, Michele K., and Benjamin F. Cravatt. "STRUCTURE AND FUNCTION OF FATTY ACID AMIDE HYDROLASE." Annual Review of Biochemistry 74, no. 1 (2005): 411–32. http://dx.doi.org/10.1146/annurev.biochem.74.082803.133450.

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9

Mcguire, Edward J., Robert H. Gray, and Felix A. De La Iglesia. "Chemical Structure-Activity Relationships: Peroxisome Proliferation and Lipid Regulation in Rats." Journal of the American College of Toxicology 11, no. 3 (1992): 353–61. http://dx.doi.org/10.3109/10915819209141875.

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Studies described here address structure-activity relationships of novel hypolipidemic agents that induce peroxisome proliferation. Male rats were given equivalent doses of three well-studied fibrates, fibrate amides, and structurally dissimilar agents. Aryloxyalkanoic acids, amide analogs, and thio, benzimidazole, phenylpiperazine, and oxazole derivatives induced peroxisome proliferation and decreased plasma cholesterol and triglyceride levels. These compounds contain an acidic function or appear to be readily metabolized to a derivative with an acidic function. Substitution of this substitue
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10

Schmidtler, J., W. Schepp, I. Janczewska, et al. "GLP-1-(7-36) amide, -(1-37), and -(1-36) amide: potent cAMP-dependent stimuli of rat parietal cell function." American Journal of Physiology-Gastrointestinal and Liver Physiology 260, no. 6 (1991): G940—G950. http://dx.doi.org/10.1152/ajpgi.1991.260.6.g940.

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We investigated the effect of glucagon-like peptide 1 (GLP-1)-(7-36) amide and its molecular variants GLP-1-(1-37) and GLP-1-(1-36) amide on enzymatically dispersed enriched rat parietal cells using [14C]aminopyrine accumulation as a measure of H+ production. GLP-1-(7-36) amide was 100 times more potent than GLP-1-(1–37) and GLP-1-(1–36) amide in stimulating [14C]aminopyrine accumulation. At their maximally effective concentrations, GLP-1–(7–36) amide (10(-8) M), GLP-1–(1–37) (10(-6) M), and GLP-1–(1–36) amide (10(-6) M) reached 80-90% of the response to 10(-4) M histamine. However, the peptid
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