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Journal articles on the topic 'Amino acids Toxicology'

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1

Riahi-Zanjani, Bamdad, Mahdi Balali-Mood, Ahmad Asoodeh, Zarrin Es’haghi, and Adel Ghorani-Azam. "Potential application of amino acids in analytical toxicology." Talanta 197 (May 2019): 168–74. http://dx.doi.org/10.1016/j.talanta.2019.01.019.

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2

Salt, T. E. "Excitatory amino acids: an update." Trends in Pharmacological Sciences 11, no. 9 (1990): 352. http://dx.doi.org/10.1016/0165-6147(90)90172-5.

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3

Olney, J. W. "Excitotoxic Amino Acids and Neuropsychiatric Disorders." Annual Review of Pharmacology and Toxicology 30, no. 1 (1990): 47–71. http://dx.doi.org/10.1146/annurev.pa.30.040190.000403.

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4

Glatt, Hansruedi. "Endogenous mutagens derived from amino acids." Mutation Research/Reviews in Genetic Toxicology 238, no. 3 (1990): 235–43. http://dx.doi.org/10.1016/0165-1110(90)90015-4.

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5

Burnett, Christina L., Bart Heldreth, Wilma F. Bergfeld та ін. "Safety Assessment of α-Amino Acids as Used in Cosmetics". International Journal of Toxicology 32, № 6_suppl (2013): 41S—64S. http://dx.doi.org/10.1177/1091581813507090.

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The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of α-amino acids, which function primarily as hair- and skin-conditioning agents in cosmetic products. The safety of α-amino acids as direct food additives has been well established based on extensive research through acute and chronic dietary exposures. The Panel focused its review on dermal irritation and sensitization data relevant to the use of these ingredients in topical cosmetics. The Panel concluded that α-amino acids were safe as cosmetic ingredients in the practices of use and concentration of this safety assessm
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6

Zili Zhang and Jie Yang. "Effects of amino acids on sister-chromatid exchanges." Mutation Research/Genetic Toxicology 280, no. 4 (1992): 279–83. http://dx.doi.org/10.1016/0165-1218(92)90058-8.

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7

Meijer, A. J. "Insulin-Dependent Signaling: Regulation by Amino Acids and Energy." Toxicology Mechanisms and Methods 14, no. 1-2 (2004): 31–34. http://dx.doi.org/10.1080/15376520490257419.

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8

Olga A. Gracheva, Alizade S. Gasanov, Damir R. Amirov, et al. "Study of the effect of different levels of arginine in feed on broiler chickens." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 908–12. http://dx.doi.org/10.26452/ijrps.v11i1.1913.

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Amino acids are the basic structural units of protein molecules in the body. Currently, about 300 amino acids are known, of which 26 are studied best. Amino acids or their derivatives (for example, immune bodies) are part of enzymes, hormones, pigments, and other specific substances that play a crucial role in digestive and metabolic processes. In the process of metabolism, many amino acids are synthesized in the body from other amino acids or compounds, and therefore they are called interchangeable. Amino acids that are not synthesized in the body or are formed in insufficient quantities are
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9

Riepe, Matthias, Peter S. Spencer, Fernand Lambein, Albert C. Ludolph, and Charles N. Allen. "In vitro toxicological investigations of isoxazolinone amino acids ofLathyrus sativus." Natural Toxins 3, no. 1 (1995): 58–64. http://dx.doi.org/10.1002/nt.2620030111.

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10

Studnitz, Wilfried, and Birgitta Haeger-Aronsen. "Urinary Excretion of Amino Acids in Lead-Poisoned Rabbits." Acta Pharmacologica et Toxicologica 19, no. 1 (2009): 36–42. http://dx.doi.org/10.1111/j.1600-0773.1962.tb00336.x.

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11

Nakamura, S., and M. Ugawa. "Formation of genotoxicity by chlorine treatment of amino acids." Mutation Research/Environmental Mutagenesis and Related Subjects 292, no. 3 (1993): 283. http://dx.doi.org/10.1016/0165-1161(93)90084-d.

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12

Burnett, Christina, Bart Heldreth, Wilma F. Bergfeld, et al. "Safety Assessment of Animal- and Plant-Derived Amino Acids as Used in Cosmetics." International Journal of Toxicology 33, no. 4_suppl (2014): 5S—12S. http://dx.doi.org/10.1177/1091581814554774.

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The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of animal- and plant-derived amino acid mixtures, which function as skin and hair conditioning agents. The safety of α-amino acids as direct food additives has been well established, based on extensive research through acute and chronic dietary exposures and the Panel previously has reviewed the safety of individual α-amino acids in cosmetics. The Panel focused its review on dermal irritation and sensitization data relevant to the use of these ingredients in topical cosmetics. The Panel concluded that these 21 ingredients
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13

Iglesias, Rosario, Letizia Polito, Massimo Bortolotti, et al. "Primary Sequence and 3D Structure Prediction of the Plant Toxin Stenodactylin." Toxins 12, no. 9 (2020): 538. http://dx.doi.org/10.3390/toxins12090538.

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Stenodactylin is one of the most potent type 2 ribosome-inactivating proteins (RIPs); its high toxicity has been demonstrated in several models both in vitro and in vivo. Due to its peculiarities, stenodactylin could have several medical and biotechnological applications in neuroscience and cancer treatment. In this work, we report the complete amino acid sequence of stenodactylin and 3D structure prediction. The comparison between the primary sequence of stenodactylin and other RIPs allowed us to identify homologies/differences and the amino acids involved in RIP toxic activity. Stenodactylin
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14

Wang, Zi-Qian, Suqin Wang, Ju-Yuan Zhang та ін. "The Proposed Neurotoxin β-N-Methylamino-l-Alanine (BMAA) Is Taken up through Amino-Acid Transport Systems in the Cyanobacterium Anabaena PCC 7120". Toxins 12, № 8 (2020): 518. http://dx.doi.org/10.3390/toxins12080518.

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Produced by cyanobacteria and some plants, BMAA is considered as an important environmental factor in the occurrence of some neurodegenerative diseases. Neither the underlying mechanism of its toxicity, nor its biosynthetic or metabolic pathway in cyanobacteria is understood. Interestingly, BMAA is found to be toxic to some cyanobacteria, making it possible to dissect the mechanism of BMAA metabolism by genetic approaches using these organisms. In this study, we used the cyanobacterium Anabaena PCC 7120 to isolate BMAA-resistant mutants. Following genomic sequencing, several mutations were map
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15

Shumyantseva, V. V., S. V. Meshkov, Yu D. Ivanov, O. V. Alexandrova, V. Yu Uvarov, and A. I. Archakov. "Interaction of organophosphorus analogues of amino acids with P450." Xenobiotica 25, no. 3 (1995): 219–27. http://dx.doi.org/10.3109/00498259509061846.

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16

Vijaya Vemani, Mounika P, Poulami Das, and Anand Kumar Tengli. "Amino Acids Profiling in Fruit Juices by High Performance Liquid Chromatography: A Review." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 2756–67. http://dx.doi.org/10.26452/ijrps.v11ispl4.4552.

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In the preservation of normal physiological functions, the building blocks of the body called amino acids play a crucial role. A number of valuable and nutritional phytoconstituents are contained in fruit juices, such as vitamins, minerals, microelements, organic acids, antioxidants, flavonoids, amino acids and other components. Due to the growing population and demand, the quality of fruit juices is decreasing. One of the unethical and harmful practices called adulteration or food fraudulence has been adopted by most food and beverage industries. The amino acids which is one of the most impor
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17

Glawar, Andreas F. G., Sarah F. Jenkinson, Amber L. Thompson, et al. "3-Hydroxyazetidine Carboxylic Acids: Non-Proteinogenic Amino Acids for Medicinal Chemists." ChemMedChem 8, no. 4 (2013): 658–66. http://dx.doi.org/10.1002/cmdc.201200541.

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18

Sandberg, M., H. Hagberg, I. Jacobson, B. Karlsson, A. Lehmann, and A. Hamberger. "Analysis of amino acids: Neurochemical application." Life Sciences 41, no. 7 (1987): 829–32. http://dx.doi.org/10.1016/0024-3205(87)90173-1.

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19

Szabó, Mária, Vivien Bíró, Fruzsina Simon, and István Fábián. "The decomposition of N-chloro amino acids of essential branched-chain amino acids: Kinetics and mechanism." Journal of Hazardous Materials 382 (January 2020): 120988. http://dx.doi.org/10.1016/j.jhazmat.2019.120988.

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20

Nagata, Takeshi, Masako Kiyono, and Hidemitsu Pan-Hou. "Involvement of Aromatic Amino Acids in Phenylmercury Transport by MerT Protein." JOURNAL OF HEALTH SCIENCE 52, no. 4 (2006): 475–77. http://dx.doi.org/10.1248/jhs.52.475.

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21

Jaffe, Klaus, Nelson A. Zabala, Maria E. De Bellard, Martha Granier, Walkiria Aragort, and Alfonso Tablante. "Amino acids and memory consolidation in the cricket II: Effect of injected amino acids and opioids on memory." Pharmacology Biochemistry and Behavior 35, no. 1 (1990): 133–36. http://dx.doi.org/10.1016/0091-3057(90)90217-6.

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22

Nishizawa, Y., H. Tanaka, and K. Kinoshita. "Incorporation of radioactivity into amino acids and fatty acids after administration of14C-geranylgeranylacetone to rats." Xenobiotica 17, no. 4 (1987): 469–76. http://dx.doi.org/10.3109/00498258709043953.

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23

Tsubuku, Shoji, Kazuhisa Hatayama, Toyohisa Katsumata, et al. "Thirteen-Week Oral Toxicity Study of Branched-Chain Amino Acids in Rats." International Journal of Toxicology 23, no. 2 (2004): 119–26. http://dx.doi.org/10.1080/10915810490444424.

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Branched-chain amino acids (l-isoleucine, l-valine, and l-leucine) are being increasingly used in sport supplements. This study evaluated toxicological and behavioral effects of l-isoleucine (Ile), l-valine (Val), and l-leucine (Leu) during a dosing study with male and female Sprague-Dawley rats. The amino acids were incorporated into a standard diet at doses equal to 1.25%, 2.5%, and 5.0% ( w/ w). A control group of rats received a standard diet. All diets were administered ad libitum for 13 consecutive weeks. To examine stability of any potential effects, the administration period was follow
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24

Contrusciere, Valentina, Silvia Paradisi, Andrea Matteucci, and Fiorella Malchiodi-Albedi. "Branched-Chain Amino Acids Induce Neurotoxicity in Rat Cortical Cultures." Neurotoxicity Research 17, no. 4 (2009): 392–98. http://dx.doi.org/10.1007/s12640-009-9115-0.

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25

Bashir, Zafar I., and Jeremy M. Henley. "The French connection: a magnum of excitatory amino acids in Marseilles." Trends in Pharmacological Sciences 14, no. 11 (1993): 387–90. http://dx.doi.org/10.1016/0165-6147(93)90055-o.

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26

Yoshida, D., and S. Mizusaki. "Formation of mutagens by heating amino acids with addition of hydroquinone." Mutation Research/Environmental Mutagenesis and Related Subjects 147, no. 5 (1985): 277. http://dx.doi.org/10.1016/0165-1161(85)90125-6.

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27

Sabbioni, Gabriele, John H. Lamb, Peter B. Farmer, and Ovnair Sepai. "Reactions of 4 methylphenyl isocyanate with amino acids." Biomarkers 2, no. 4 (1997): 223–32. http://dx.doi.org/10.1080/135475097231599.

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28

Jones, A. W., and B. Lisander. "INTRAVENOUS AMINO-ACIDS ACCELERATE ETHANOL ELIMINATION IN HUMANS." Alcoholism: Clinical & Experimental Research 28, Supplement (2004): 8A. http://dx.doi.org/10.1097/00000374-200408002-00011.

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29

Leese, Henry J., Paul J. McKeegan, and Roger G. Sturmey. "Amino Acids and the Early Mammalian Embryo: Origin, Fate, Function and Life-Long Legacy." International Journal of Environmental Research and Public Health 18, no. 18 (2021): 9874. http://dx.doi.org/10.3390/ijerph18189874.

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Amino acids are now recognised as having multiple cellular functions in addition to their traditional role as constituents of proteins. This is well-illustrated in the early mammalian embryo where amino acids are now known to be involved in intermediary metabolism, as energy substrates, in signal transduction, osmoregulation and as intermediaries in numerous pathways which involve nitrogen metabolism, e.g., the biosynthesis of purines, pyrimidines, creatine and glutathione. The amino acid derivative S-adenosylmethionine has emerged as a universal methylating agent with a fundamental role in ep
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30

Gupta, Meenakshi, and Vijay Prabha. "Changes in Brain and Plasma Amino Acids of Mice Intoxicated with Methyl Isocyanate." Journal of Applied Toxicology 16, no. 6 (1996): 469–73. http://dx.doi.org/10.1002/(sici)1099-1263(199611)16:6<469::aid-jat373>3.0.co;2-q.

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31

Eriksson, T., K. Wiesel, L. Voog, and M. Hagman. "Diurnal rhythms in rat plasma amino acids." Life Sciences 45, no. 11 (1989): 979–86. http://dx.doi.org/10.1016/0024-3205(89)90151-3.

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32

Yokoyama, Takashi, Shinya Miyazaki, Satoshi Ikawa, Yoichi Nakashima, and Katsuhisa Kitano. "Kinetics Analysis of the Reactions between Peroxynitric Acid and Amino Acids." Chemical Research in Toxicology 33, no. 7 (2020): 1633–43. http://dx.doi.org/10.1021/acs.chemrestox.9b00408.

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33

Nickel, A., G. Kottra, G. Schmidt, J. Danier, T. Hofmann, and H. Daniel. "Characteristics of transport of selenoamino acids by epithelial amino acid transporters." Chemico-Biological Interactions 177, no. 3 (2009): 234–41. http://dx.doi.org/10.1016/j.cbi.2008.09.008.

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34

Cordomí, Arnau, José C. Gómez-Tamayo, Véronique Gigoux, and Daniel Fourmy. "Sulfur-containing amino acids in 7TMRs: molecular gears for pharmacology and function." Trends in Pharmacological Sciences 34, no. 6 (2013): 320–31. http://dx.doi.org/10.1016/j.tips.2013.03.008.

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35

Elwin, Carl-Eric. "Emetic and Gastric Secretory Stimulating Action by Esters of some Amino Acids." Acta Pharmacologica et Toxicologica 28, no. 3 (2009): 161–76. http://dx.doi.org/10.1111/j.1600-0773.1970.tb00541.x.

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36

Lodge, David, and Graham Collingridge. "Les agents provocateurs: A series on the pharmacology of excitatory amino acids." Trends in Pharmacological Sciences 11, no. 1 (1990): 22–24. http://dx.doi.org/10.1016/0165-6147(90)90037-9.

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37

Headley, P. Max, and Sten Grillner. "Excitatory amino acids and synaptic transmission: the evidence for a physiological function." Trends in Pharmacological Sciences 11, no. 5 (1990): 205–11. http://dx.doi.org/10.1016/0165-6147(90)90116-p.

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38

Blecharz-Klin, Kamilla, Ilona Joniec-Maciejak, Agnieszka Piechal, Justyna Pyrzanowska, Adriana Wawer, and Ewa Widy-Tyszkiewicz. "Paracetamol impairs the profile of amino acids in the rat brain." Environmental Toxicology and Pharmacology 37, no. 1 (2014): 95–102. http://dx.doi.org/10.1016/j.etap.2013.11.004.

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39

Bhat, Musadiq Hussain, Mufida Fayaz, Amit Kumar, Alamgir Ahmad Dar, and Ashok Kumar Jain. "Chromatographic Method for Determination of the Amino Acid Content in Dioscorea bulbifera L. Tubers by RP-HPLC." Pharmaceutical Sciences 25, no. 1 (2019): 65–69. http://dx.doi.org/10.15171/ps.2019.10.

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Background: The present study was carried out for determination of amino acid content in tubers of Dioscorea bulbifera using reverse-phase high-performance liquid chromatography. Methods: The method involved the vapor phase hydrolysis of the sample, automated derivatisation of the amino acids with the aid of AccQ-Fluor reagent kit, separated on a high performance liquid chromatography equipped with photo diode array (HPLC-PDA) at 254 nm having column temperature of 37 ºC. Results: The proportional molar concentration for each amino acid was calculated based on the concentration of standard ami
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40

Gomes, J., A. H. Dawodu, O. Lloyd, D. M. Revitt, and S. V. Anilal. "Hepatic injury and disturbed amino acid metabolism in mice following prolonged exposure to organophosphorus pesticides." Human & Experimental Toxicology 18, no. 1 (1999): 33–37. http://dx.doi.org/10.1177/096032719901800105.

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1 Chronic occupational exposure to organophosphorus and carbamate-type pesticides significantly inhibits acetylcholinesterase activity and causes morbidity. This study on mice was designed to evaluate their amino profile and to identify signs of hepatic dysfunction following their chronic exposure to mixtures of organophosphorus pesticides. 2 Laboratory mice were exposed to a formulated mixture of the six organophosphorus pesticides (Dimethoate, Chlorpyrifos, Profenofos, Pirimiphos methyl, Triazophos and Dimethoate) most commonly used in agriculture in this region of the Middle East. Doses (10
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41

Abe, Takashi, Yasuaki Hariya, Nobufumi Kawai, and Akiko Miwa. "Comparative study of amino acid composition in an extract from hornet venom sacs: High content of neuroactive amino acids in Vespa." Toxicon 27, no. 6 (1989): 683–88. http://dx.doi.org/10.1016/0041-0101(89)90019-6.

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42

Leite, Ana Cristina Lima, Fábio Fernandes Barbosa, Marcos Veríssimo de Oliveira Cardoso, et al. "Phthaloyl amino acids as anti-inflammatory and immunomodulatory prototypes." Medicinal Chemistry Research 23, no. 4 (2013): 1701–8. http://dx.doi.org/10.1007/s00044-013-0730-1.

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43

Idrees, Muhammad, Afzal R. Mohammad, Nazira Karodia, and Ayesha Rahman. "Multimodal Role of Amino Acids in Microbial Control and Drug Development." Antibiotics 9, no. 6 (2020): 330. http://dx.doi.org/10.3390/antibiotics9060330.

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Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms including those in the microbial world. They are utilised as nutrients and control many biological functions in microorganisms such as cell division, cell wall formation, cell growth and metabolism, intermicrobial communication (quorum sensing), and microbial-host interactions. Amino acids in the form of enzymes also play a key role in enabling microbes to resist antimicrobial drugs. Antimicrobial resistance (AMR) and microbial biofilms are posing a great threat to the world’s human and animal population and a
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44

Yun, Kang Uk, Chang Seon Ryu, Ji-Yoon Lee, et al. "Hepatic metabolism of sulfur amino acids in db/db mice." Food and Chemical Toxicology 53 (March 2013): 180–86. http://dx.doi.org/10.1016/j.fct.2012.11.046.

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45

Nigam, R., and M. M. Srivastava. "Effects of carboxylic and amino acids on Cd uptake byLycopersicum esculentum." Chemical Speciation & Bioavailability 17, no. 1 (2005): 19–26. http://dx.doi.org/10.3184/095422905782774973.

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46

Febriyenti, A. . Almahdy, and Dwi Mulyani. "AMINO ACIDS AND FATTY ACIDS PROFILES OF EEL (Monopterus albus) WATER EXTRACTS." Rasayan Journal of Chemistry 12, no. 03 (2019): 1591–94. http://dx.doi.org/10.31788/rjc.2019.1234071.

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47

Anders, M. W., Adnan A. Elfarra, and Lawrence H. Lash. "Cellular effects of reactive intermediates: Nephrotoxicity of S-conjugates of amino acids." Archives of Toxicology 60, no. 1-3 (1987): 103–8. http://dx.doi.org/10.1007/bf00296959.

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48

Adaeze, Bob-Chile A., and Peter U. Amadi. "Evaluation of Bioactive Component, Free Radical Scavenging Potentials and Protein Qualities of Gomphrena celosoides and Zea mays Leaves." Current Bioactive Compounds 16, no. 7 (2020): 1108–15. http://dx.doi.org/10.2174/1573407215666191125105900.

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Background: The assessment of underexploited leaves has become crucial to supplement the rapidly depleting sources of bioactive components as well as provide available nutrient sources for local inhabitants. Methods: This study thus investigated the bioactive components of the oil, and fatty acid composition, free radical scavenging potentials, and protein qualities of leaves of Z. mays and G. celosioides using standard methods. The bioactive components of the oils and fatty acids were determined by Gas Chromatograpy, while the amino acid and in-vitro antioxidant potentials were determined usi
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49

Sastry, BV. "Placental toxicology: tobacco smoke, abused drugs, multiple chemical interactions, and placental function." Reproduction, Fertility and Development 3, no. 4 (1991): 355. http://dx.doi.org/10.1071/rd9910355.

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There are increasing numbers of reports on the tobacco smoking and ingestion of abused drugs (e.g. morphine, cocaine) by pregnant women and the effects of the substances on the developing fetus and newborn infant. The passage of drugs and chemicals from the mother to the fetus is influenced by the placental transport and metabolism of the substances. Further, these drugs and chemicals affect the nutrient transport systems in the placenta. The three major drugs of abuse-nicotine, morphine and cocaine-depress both active amino-acid uptake by human placental villi and transplacental amino-acid tr
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50

Chohan, Zahid H. "Symmetric 1,1'-Dimethylferrocene-Derived Amino Acids: Their Synthesis, Characterization, Ligational and Biological Properties With Cu(II), Co(II) and Ni(II) Ions." Metal-Based Drugs 7, no. 4 (2000): 177–83. http://dx.doi.org/10.1155/mbd.2000.177.

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Some novel symmetric 1,1′-dimethylferrocene derived amino acids have been prepared by the reaction of 1,1′-ferrocenedimethyldichloride with amino acids (glycine, alanine, phenylalanine and tyrosine). Their Cu(II), Co(II) and Ni(II) complexes, of the type [M(L)] where [M = Cu(II) and L = L1-L5] and [M(L)Cl2] where [M-Co(II)and Ni(II), L = L1-L5] have been prepared. The dicarboxylic acids and their metal complexes were characterized by their physical, analytical and spectral data. The [M(L)] complexes showed a square planar geometry whereas an octahedral geometry was observed for [M(L)Cl2] compl
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