Relevant bibliographies by topics / Aminocyclitols

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Aminocyclitols'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 September 2023

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Journal articles on the topic "Aminocyclitols"

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Walker, James B. "Enzymatic Synthesis of Aminoglycoside Antibiotics: Novel Adenosylmethionine:2-Deoxystreptamine N-Methyltransferase Activities in Hygromycin B- and Spectinomycin-Producing Streptomyces spp. and Uses of the Methylated Products." Applied and Environmental Microbiology 68, no. 5 (2002): 2404–10. http://dx.doi.org/10.1128/aem.68.5.2404-2410.2002.

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ABSTRACT Aminocyclitols structurally related to streptamine, a 1,3-diaminocyclitol, are common components of the RNA-binding aminoglycoside antibiotics. The respective aminocyclitol cores of hygromycin B and spectinomycin are N 3-methyl-2-deoxy-d-streptamine and N 1,N 3-dimethyl-2-epi-streptamine. Adenosyl[methyl-14C]methionine:2-deoxystreptamine N-methyltransferase activities were detected in extracts of early-stationary-phase mycelia of the hygromycin B producer Streptomyces hygroscopicus subsp. hygroscopicus ATCC 27438 and the spectinomycin producer Streptomyces flavopersicus ATCC 19756. Ex
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Diaz, L., and A. Delgado. "Medicinal Chemistry of Aminocyclitols." Current Medicinal Chemistry 17, no. 22 (2010): 2393–418. http://dx.doi.org/10.2174/092986710791698512.

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Trost, Barry M., and Sushant Malhotra. "Asymmetric Stereodivergent Strategy Towards Aminocyclitols." Chemistry - A European Journal 20, no. 27 (2014): 8288–92. http://dx.doi.org/10.1002/chem.201402175.

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Braun, H. "Synthesis of chiral aminocyclitols via epoxyepimination." Tetrahedron: Asymmetry 1, no. 6 (1990): 395–402. http://dx.doi.org/10.1016/s0957-4166(00)82400-3.

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Alegret, Carlos, Jordi Benet-Buchholz, and Antoni Riera. "Stereodivergent Syntheses of Conduramines and Aminocyclitols." Organic Letters 8, no. 14 (2006): 3069–72. http://dx.doi.org/10.1021/ol061022e.

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Braun, H., W. Burger, G. Kresze, F. P. Schmidtchen, J. L. Vaerman, and H. G. Viehe. "Synthesis of chiral aminocyclitols via epoxyepimination." Tetrahedron: Asymmetry 1, no. 6 (1990): 403–15. http://dx.doi.org/10.1016/0957-4166(90)90041-8.

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Egido-Gabás, Meritxell, Pedro Serrano, Josefina Casas, Amadeu Llebaria, and Antonio Delgado. "New aminocyclitols as modulators of glucosylceramide metabolism." Org. Biomol. Chem. 3, no. 7 (2005): 1195–201. http://dx.doi.org/10.1039/b411473f.

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Trost, Barry M., and Sushant Malhotra. "ChemInform Abstract: Asymmetric Stereodivergent Strategy Towards Aminocyclitols." ChemInform 45, no. 52 (2014): no. http://dx.doi.org/10.1002/chin.201452056.

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Delgado, Antonio. "Recent Advances in the Chemistry of Aminocyclitols." European Journal of Organic Chemistry 2008, no. 23 (2008): 3893–906. http://dx.doi.org/10.1002/ejoc.200800238.

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Ho, Y. "In-vitro activities of aminoglycoside-aminocyclitols against mycobacteria." Journal of Antimicrobial Chemotherapy 40, no. 1 (1997): 27–32. http://dx.doi.org/10.1093/jac/40.1.27.

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Dissertations / Theses on the topic "Aminocyclitols"

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Demir, (davulcu) Emine. "Development Of New Synthetic Strategies For Aminocyclitols." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/1045525/index.pdf.

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Cyclitols are of great importance due to their biological activities playing a crucial role in living organisms as well as their synthetic usefulness in the synthesis of other natural compounds or pharmaceuticals. In this study, new synthetic strategies leading to the aminocyclitols were investigated. The synthesis of aminoconduritol and aminoinositol derivatives (173 and 174) were achieved starting from easily available compound, 7-oxa-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride (166) obtained from the Diels-Alder reaction of furan and maleic anhydride. The anhydride functionality in
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Ekmekci, Zeynep. "Development Of New Synthetic Methodologies For Aminocyclitols." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613906/index.pdf.

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Aminocyclitols are cyclitols in which at least one of the hydroxyl groups is exchanged with an amino functional group. In turn, they constitute a wide group of natural products with interesting biological properties and are widely distributed throughout. In particular, antibiotics containing an aminocyclitol unit have stimulated the development of synthetic methodologies in the search for analogues with enhanced pharmacological profiles. In this study, three different methods were applied to synthesize diaminoconduritol derivative 202. In the first method, 1,2,3,6-tetraphthalic anhydrate (196)
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Ozturk, Nihal. "The Development Of Novel Syntheses For Aminocyclitol Derivatives." Master's thesis, METU, 2003. http://etd.metu.edu.tr/upload/4/1050087/index.pdf.

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Aminocyclitols have attracted a great deal of attention in recent years because of diverse biological activities exhibited by them and also synthetic usefulness in the synthesis of other natural compounds or pharmaceuticals. In this study, novel synthetic strategies leading to aminocyclitol derivatives were investigated and the synthesis of aminotetrol derivative (113) was achieved successfully. Moreover, by the use of singlet oxygen reactions having considerable synthetic utilities in organic chemistry we developed new synthetic methodologies for the aminoquercitol and aminoconduritol derivat
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Korkmaz, Cokol Nalan. "Development Of The Methodology For The Synthesis Of Bis-aminoinositols." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613580/index.pdf.

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Cyclitols are cyclic compounds having hydroxyl groups which attached to different carbons on the ring. Cyclitols have attracted a great deal of attention for having diverse biological activities. Cyclic alcohols play an important role in biological processes such as inhibition of glycosidase, cellular recognition, and signal transduction. In addition to this, these compounds are very important molecules due to being capable of using while synthesizing natural products or pharmaceuticals. In this study, development of new methodology for the synthesis of bis-aminoinositol derivatives was aimed.
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Monlleó, Mas Ester. "Aminocyclitol and iminosugar derivatives related to Gauche disease." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/400871.

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Gaucher disease (GD) is one of the most prevalent lysosomal storage diseases.A mutation on gene gba1 generates a misfolded enzyme acid β-glucosidase. Due to this, this enzyme is not properly transported from the endoplasmic reticulum (ER) to the lysosome, with the consequent reduction of its lysosomal activity. This leads to the accumulation of the substrate glucosylceramide (GluCer) in the lysosomes of macrophages that originate the clinical symptoms. Besides the expensive Enzymatic Replacement Therapy (ERT), different approaches could be useful to minimize this accumulation of GluCer. One
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El, Blidi Lahssen. "Synthèse chimioenzymatique et évaluation d'inhibiteurs potentiels de glycosidases, analogues de la valiolamine." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2006. http://tel.archives-ouvertes.fr/tel-00707646.

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Les glycosidases sont des enzymes impliquées dans un grand nombre de processus biologiques. Leurs inhibiteurs présentent un potentiel thérapeutique en tant qu'agents antidiabétiques, agents antiviraux ou agents pour traiter des maladies génétiques. Au cours de ce travail, nous nous sommes attachés à développer une voie de synthèse chimioenzymatique permettant d'accéder à des analogues de la valiolamine, puissant inhibiteurs d'alpha-glucosidases. Les aminocyclitols que nous avions pour objectif de préparer diffèrent de la valiolamine par la position du groupement amino et des stéréochimies des
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Oelze, Benjamin. "Synthesen von Aminocyclitol-Bausteinen und deren Verknüpfung durch Olefinmetathese." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=980450349.

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Husson, Christian. "Complexation de lanthanides trivalents par des ligands azotés et oxygénés à base cyclohexanique." Université Joseph Fourier (Grenoble), 1998. http://www.theses.fr/1998GRE10163.

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Ce travail concerne l'elaboration et l'etude de ligands (azotes et oxygenes) a base cyclohexanique, susceptibles d'effectuer la separation selective des lanthanides et des actinides trivalents. Les ligands ont ete obtenus soit par hydrogenation catalytique d'aromatiques polyfonctionnels, soit par substitution nucleophile sur des derives cyclohexaniques polysulfones. Des complexes ml et ml#2 ont ete caracterises en phase solide (par diffraction des rayons x) avec les ligands polyhydroxyles l1 (1,3,5-cyclohexane-triol) et l2 (1,2,3-cyclohexane-triol). Les complexes se forment dans des solvants o
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Camps, Bres Flora. "Synthèse d'aminocyclitols, inhibiteurs potentiels de glycosidases lysosomales, via des aldolases." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2010. http://tel.archives-ouvertes.fr/tel-00629666.

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Les glycosidases sont des enzymes impliquées dans de nombreux processus biologiques. Entre autres, elles sont responsables de la dégradation des déchets polysaccharidiques de nos cellules. Lorsqu'une modification génétique touche un gène qui code pour une de ces enzymes, des pathologies graves regroupées sous l'appellation de " maladies lysosomales " peuvent être déclenchées. L'objectif de ce projet a été de proposer une méthode de synthèse efficace de molécules potentiellement actives spécifiquement sur l'une ou l'autre de ces maladies. Les molécules ciblées sont des inhibiteurs de glycosidas
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Li, Heng-Yi, and 李恆毅. "Synthesis of aminocyclitols(deoxyinosamines) and polyhydroxyindolizidines for potential glycosidase inhibitors." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/67744090257103290862.

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碩士<br>淡江大學<br>化學學系碩士班<br>95<br>Naturally occurring polyhydroxylated aminosugars are considered to be potential glycosidase inhibitors. These glycosidase inhibitors possess potential in the treatment of cancers, HIV, diabetes and metabolic disorders. Especially in diabetes, it is estimated that the number of diabetes patients is expectd to rise from the current estimated of 150 million to 220 million in 2010. Polyhydroxylated aminosugars have been known as glycosidase inhibitors. They display the same stereochemistry as the corresponding hexoses, exceptor nitrogen atom replacing the original o
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Book chapters on the topic "Aminocyclitols"

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Veyssier, P., and A. Bryskier. "Aminocyclitol Aminoglycosides." In Antimicrobial Agents. ASM Press, 2014. http://dx.doi.org/10.1128/9781555815929.ch16.

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Sharpe, Robert J. "Asymmetric Synthesis of the Aminocyclitol Pactamycin, A Universal Translocation Inhibitor." In Stereoselective Desymmetrization Methods in the Assembly of Complex Natural Molecules. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39025-3_1.

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Tsunoda, Takeshi, and Taifo Mahmud. "Aminocyclitols." In Comprehensive Natural Products III. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-409547-2.14708-0.

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Lovering, Andrew M., and David S. Reeves. "Aminoglycosides and aminocyclitols." In Antibiotic and Chemotherapy. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-7020-4064-1.00012-9.

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Hotta, K., J. Davies, and M. Yagisawa. "Aminoglycosides and Aminocyclitols (Other Than Streptomycin)." In Genetics and Biochemistry of Antibiotic Production. Elsevier, 1995. http://dx.doi.org/10.1016/b978-0-7506-9095-9.50030-7.

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