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Dissertations / Theses on the topic 'Aminopyridín'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Sommer, Lorenz. "Der Aminopyrin-Atemtest bei Diabetes /." [S.l : s.n.], 1985. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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2

Rodriguez-Leal, Francisco Alejandro, Rocco Haase, Katja Thomas, et al. "Fampridine response in MS patients with gait impairment in a real-world setting: Need for new response criteria?" Sage, 2018. https://tud.qucosa.de/id/qucosa%3A35526.

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Objective: The primary objective of this real-world study was to describe the response to fampridine and changes of gait parameters in multiple sclerosis (MS) patients’ walking disability (Expanded Disability Status Scale (EDSS): 4–7) after treatment with fampridine for 2 weeks as recommended by the European Medicines Agency (EMA) and compare it with the overall physician’s judgement. Methods: A total of 211 adult MS patients were analyzed using a multimodal gait assessment including the timed 25-foot walk test (T25FW), 2-minute walking test (2-MWT), 12-item Multiple Sclerosis Walking Scale (M

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3

Qiao, Juan. "Neurophysiological effects of 4-aminopyridine in spinal cord injury." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq28515.pdf.

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4

Statton, Heidi. "Prolonged epileptiform activity induced by 4-aminopyridine in rat hippocampus." Thesis, University of Birmingham, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409065.

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5

Barbar, Élie. "Effets de la 4-aminopyridine sur le lymphocyte T Jurkat." [S.l. : s.n.], 2004.

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6

Soler, Vives Marta. "Peptide conjugates containing chlorambucil or tetradentate aminopyridine ligands for anticancer treatment." Doctoral thesis, Universitat de Girona, 2015. http://hdl.handle.net/10803/285974.

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Nowadays, the search for new drugs against cancer is one of the major goals to improve the quality of life of patients. The development of more selective treatments against cancer cells may lead to a significant reduction of the side-effects, being one of the most important topics in current research. In this regard, cell-penetrating peptides (CPPs) have been described to efficiently transport therapeutic molecules across the cell membrane. Furthermore, some metal complexes based on platinum (cisplatin and derivatives) are used in current chemotherapy. Despite their efficacy, these drugs displ

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7

Wurzbacher, Steffen Rüdiger Josef. "Der Aminopyrin-Atemtest als hepatischer Verlaufsparameter in der abdominalen Sepsis." kostenfrei, 2008. http://mediatum2.ub.tum.de/doc/648791/648791.pdf.

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8

Naumann, Thomas [Verfasser]. "Differentielle Wirkung von 4-Aminopyridin auf die verschiedenen Komponenten des Downbeat-Nystagmus-Syndroms / Thomas Naumann." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2018. http://d-nb.info/1152029797/34.

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9

Dulin, Renaud. "La 4-aminopyridine et la 3,4-diaminopyridine : propriétés pharmacologiques, statut, utilisations thérapeutiques." Bordeaux 2, 1999. http://www.theses.fr/1999BOR2P063.

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10

Barbarosie, Michaela T. (Michaela Teodora). "Presynaptic control of 4-aminopyridine-induced activity in the in vitro adult rat hippocampus." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=22716.

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The convulsant and K$ sp+$ channel blocker, 4-aminopyridine (4AP), induces two types of synchronous, spontaneous field potentials in the stratum radiatum of the CA3 subfield, in an in vitro hippocampal slice obtained from adult rat. The first type of activity is a positive-going interictal-like potential that corresponds to a burst of population spikes, and is abolished by non-NMDA receptor antagonists; the second type of field potential is a low frequency, negative going synchronous event which is sensitive to GABA$ rm sb{A}$ receptor antagonism. Knowing that in the hippocampus, adenosine A1

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11

Collin, Xavier. "N-pyridinyl(methyl)phtalimides et analogues structuraux inhibiteurs de la production du tumor necrosis factor alpha (tnf alpha) a potentialite anti-inflammatoire (doctorat : chimie therapeutique)." Nantes, 2000. http://www.theses.fr/2000NANT17VS.

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12

Duret, Guillaume. "Synthèse de 4-aminopyridines par réaction de cycloaddition (4+2) d’ynamides." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAF012/document.

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Les motifs de type pyridine sont des motifs centraux dans de nombreux domaines, aussi bien rencontrés dans divers principes actifs en chimie médicinale, qu’en agrochimie, chimie des matériaux et des polymères, et enfin en synthèse organique de manière générale. De nombreuses voies d'accès toujours plus simples et directes à des motifs de type pyridine polysubstituées ont été proposées dans la littérature, et, parmi ceux-ci, le motif de type aminopyridine fusionnée à retenu notre attention. En effet peu de rapports d'un tel motif sont fait dans la littérature, en partie en raison du défi synthé

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13

Perreault, Paul. "A contribution to the understanding of the effects of 4-aminopyridine on rat hippocampal slices /." Thesis, McGill University, 1990. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74562.

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The aim of the work presented in this thesis was to study the effects of 4-aminopyridine (4-AP, 5-100 $ mu$M) on rat hippocampal slices maintained in vitro. Two types of synchronous potentials were evoked by 4-AP: epileptiform bursts and GABA-mediated potentials. Bursts were initiated in CA3 by giant excitatory postsynaptic potentials (EPSPs) mediated by quisqualate/kainate receptors and involving recurrent excitatory pathways. This epileptiform activity occurred despite the presence of potentiated inhibitory postsynaptic potentials (IPSPs) and could propagate to CAl. The second type of activi

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14

Acuña-Parés, Ferran. "Theoretical study of water oxidation and reduction mechanisms by aminopyridine first row transition metal catalysts." Doctoral thesis, Universitat de Girona, 2016. http://hdl.handle.net/10803/398411.

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One of the major current scientific goals is the development of renewable energy sources. An effective alternative to fossil fuels consists in the conversion of the sunlight energy into chemical fuels. The molecular hydrogen from water is considered the most promising energy carrier. In the natural photosynthesis the solar energy is stored into the carbohydrate chemical bonds derived from water and CO2. The key step of this process is the photo-oxidation of H2O molecules into O2, which provides the protons and electrons needed to produce H2. A detailed knowledge of the reaction mechanisms res

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15

Costello, Sarah Mary. "Hyperactivation of human sperm by 4-Aminopyridine : key role for mobilisation of stored Ca2+ in the sperm neck." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1320/.

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Within the female reproductive tract mammalian sperm gradually develop hyperactivated motility, triggered by increased flagellar Ca2+ resulting in deep flagellar bends. Two sources of Ca2+ may contribute to the regulation of hyperactivation. Ca2+ influx at the plasma membrane is crucial and the sperm specific CatSpers channels are of great importance. In addition, studies on sperm have provided strong evidence that Ca2+ stored in the region of the sperm neck contributes to regulation of flagellar activity. 4-aminopyridine caused robust and persistent hyperactivation of motility in human sperm.

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16

Ye, Fei. "Ru- and Rh-catalyzed [2+2+2] cycloadditions : an access to fluorenone, 2-aminopyridine, and 1,3-dihydroisobenzofuran derivatives." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066347/document.

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Ce manuscrit traite de la mise au point d’une méthode d’accès éco-compatible à des squelettes carbocycliques et hétérocycliques, présents dans de nombreux composés d’intérêt biologique. Cette méthode met en œuvre une réaction de cycloaddition [2+2+2] catalysée par un métal de transition. Dans un premier temps, une voie d’accès à des fluorénones hautement substituées, ainsi qu’à des analogues a été développée. Cette voie utilise une réaction de cycloaddition [2+2+2] de diynes-[alpha, omega] pontés par un groupe benzoyle, avec des alcynes, en présence de RuCl3·nH2O. Dans un deuxième temps, des d

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17

Barbar, Élie. "Effets de la 4-aminopyridine sur le lymphocyte T Jurkat influx calcique, induction de l'apoptose et perméation d'ions." Thèse, Université de Sherbrooke, 2004. http://savoirs.usherbrooke.ca/handle/11143/4245.

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La 4-aminopyridine (4-AP) est utilisée dans le traitement expérimental de plusieurs maladies du système nerveux. Son action bénéfique est médiée via le blocage de canaux potassiques, ce qui améliore la transmission de l'influx nerveux ainsi que la force motrice musculaire. Outre sa propriété de bloquer les canaux K + , la 4-AP possède plusieurs autres effets cellulaires qui ne sont pas complètement caractérisés. Par exemple, elle alcalinise le milieu intracellulaire, induit une réponse calcique et peut causer la mort cellulaire. Dans une première étude, nous avons utilisé la lignée de lymphocy

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18

Schulze, Christina. "Prüfung der Leberfunktion mit Hilfe der 13C-Atemteste Aminopyrin und Methacetin bei Patienten mit einer kompletten Querschnittlähmung unterschiedlicher Höhenlokalisation." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965897400.

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19

Mouchonière, Maud. "Effets de l'hypertrophie sur l'adaptation du potentiel d'action cardiaque aux changements de frequence chez l'homme et le rat." Clermont-Ferrand 1, 1994. http://www.theses.fr/1994CLF1MM10.

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20

Billinghurst, Lori L. "Effects of some novel anticonvulsant drugs on the synchronous activity recorded in the presence of 4-aminopyridine in the rat hippocampus." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27283.

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Despite advances in understanding the pathogenesis of epilepsy, it remains a significant therapeutic challenge. Studies of the novel antiepileptic drugs (AEDs) gabapentin, lamotrigine and topiramate suggest that they will aid in managing seizures refractory to more established agents. However, a consensus has not been reached on their respective cellular and molecular mechanisms of action. Moreover, only a limited number of studies have examined the effects of these drugs in infants and children, a patient population with a particular propensity for seizure generation. Therefore, the objective

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21

Billinghurst, Lori L. "Effects of some novel anticonvulsant drugs on the synchronous activity recorded in the presence of 4-aminopyridine in the rat hippocampus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0004/MQ29657.pdf.

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22

Jonsson, Tobias. "Peroxyoxalate Chemiluminescence for Miniaturized Analytical Flow Systems." Doctoral thesis, Umeå University, Chemistry, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-16.

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<p>This thesis deals with the peroxyoxalate chemiluminescence (POCL) reaction and its application as a detection technique in flow systems for chemical analysis. Particularly, miniaturized flow systems aimed for separation of molecules. In such systems, a high light intensity and a rapid development of the emission are the desired reaction characteristics, for reasons discussed in this text. The work tries to develop an understanding of the chemical processes involved in POCL, with special emphasis to the species favoring or hindering a rapid light evolution. Hence, is the focus placed on the

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23

Gigout, Sylvain. "Synchronisation des réseaux neuronaux dans l' épilepsie du lobe temporal chez l' homme et l' épilepsie-absences chez l' animal : rôle des jonctions communicantes." Paris 6, 2005. http://www.theses.fr/2005PA066506.

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24

Girardeau, Elodie. "Développement et optimisation de nouvelles familles de molécules hétérocycliques ayant un intérêt commercial en tant que building blocks." Thesis, Aix-Marseille 3, 2011. http://www.theses.fr/2011AIX30030.

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Ce manuscrit décrit la synthèse et la conception de 3 nouvelles familles de molécules, les [alpha],[alpha]-diméthylamines, les 6-nitroaminopyridines et les benzimidazoles substitués. L’étude des [alpha],[alpha]-diméthylamines nous a amené à développer une voie de synthèse originale en utilisant les propriétés chimiques du chlorure de cérium, qui, lorsqu’il est complexé avec un organolithien permet d’alkyler deux fois une fonction nitrile. Une étude exhaustive des propriétés chimiques du cérium et du chlorure de cérium en synthèse organique a également été menée. La synthèse totale de la 6-nitr

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25

Tber, Zahira. "L'imidazo[1,2-a]pyridine : fonctionnalisation et synthèse des nouveaux polyhétérocycles." Thesis, Orléans, 2016. http://www.theses.fr/2016ORLE2021.

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Les préparations de composés comportant un noyau imidazo[1,2-a]pyridinique constituent un thème de recherche important en synthèse organique, compte tenu des nombreuses activités biologiques qu’ils peuvent présenter. Dans la première partie, nous nous sommes concentrés sur le développement de nouvelles stratégies rapides et efficaces basées sur l’utilisation de cuivre et de fer pour fonctionnaliser la position 6 du cycle imidazo[1,2-a]pyridine avec diverses amines et divers thiols. Ensuite, nous avons appliqué avec succès cette procédure pour la préparation de thioéthers symétriques et dissymé

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26

Brito, Verônica Bidinotto. "Os Efeitos de Organocalcogêneos e de 2,3-Dimercaptopropanol Sobre Convulsão Química e Letalidade Induzidas por Pentilenotetrazol e 4-Aminopiridina em Camundongos." Universidade Federal de Santa Maria, 2007. http://repositorio.ufsm.br/handle/1/11069.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Experimental models of seizure in animals have represented an important role for the understanding of the physiological and behavioural alterations associated with the human epilepsy. The induction of partial or generalized seizures is an efficient method for evaluating both the susceptibility to seizures and to investigate new anticonvulsant agents. In this sense, studies showed that the convulsive actions of the diphenyl diselenide (PhSe)2 and 2,3-dimercaptopropanol (BAL) compounds are inhibited by diazepam and phenobarbital, two

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27

Galve, Murillo Iñaki. "Síntesis de pirido[2,3-d]pirimidin-7(8H)-onas 2-arilamino sustituidas y derivados." Doctoral thesis, Universitat Ramon Llull, 2013. http://hdl.handle.net/10803/101403.

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Les Cinases de Proteïna (PKs) estan implicades en processos fonamentals de la regulació del cicle cel•lular. L’acumulació d’anomalies als mecanismes de control i el comportament disfuncional que se’n deriva han estat detectats a cèl•lules de diferents teixits afectades per càncer, desordres immunològics, endocrins, nerviosos, neurodegenaratius, cardiovasculars, malalties infeccioses, diabetis, Alzheimer, asma, restenosi, arteriosclerosi, leucèmia, artritis, etc. Però d’entre totes les PKs, les Cinases de Tirosina (TKs) han estat destacades com a l’element central de tots aquests processos i, p

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28

Dobrovodská, Gabriela. "Oxid dusnatý a jeho neurofyziologická role." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-310899.

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Title: Nitric oxide and its neurophysiologic role Objectives: The main aim of my diploma work is to evaluate the role of nitric oxide and its effects during epileptic seizure in rats. I summarize the present knowledge about nitric oxide and its effects on human organism in the theoretical section of this paper and I will suppose the positive effect of nitric oxide inhibitor in epileptic seizures in rats by the realization of my experiment. Methods: The experiment will be performed in the laboratory of Academy of Science of Czech Republic. Implementation will come through examining a set of ten

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29

Wu, Kuo-Hsiang, and 吳國祥. "Synthesis, Structures and Properties of Copper compounds containing4-aminopyridine." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/xr5n59.

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碩士<br>中原大學<br>化學研究所<br>102<br>Abstract The syntheses and structures of a series of Copper(II) and Copper(I) complexes containing 4-aminopyridine (L), [Cu(L)4](NO3)2 • 2EtOH, 1, [Cu(L)4]Br2 • 2EtOH, 2, and [Cu(L)4]I • 2EtOH, 3, are reported. All complexes have been structurally characterized by X-ray crystallography. The metal center of these three complexes are coordinated by four L ligands through the pyridyl nitrogen atoms to form distorted square planar geometries. Their molecules are interlinked by the O–H---O, N–H---O, N–H---X and O–H---X (X = halogen) hydrogen bonds to form 3D supramolec

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30

Chen, Mine Hong, and 陳敏鴻. "The Oxitadion of 4-Aminopyridion pentacyanoferrate(II) By Peroxydisulfate." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/73259581320389761517.

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碩士<br>中原大學<br>化學學系<br>82<br>Redox reactions of Fe(CN)5L3- [ L=4-aminopyridine(4-Ampy)、 pyridine(py)、4,4'-bipyridine (4,4'-py)、pyrazine(pz)、N- methyl- pyrazinium(Mpz+) ] with S2O82- according to Eq(1) Fe( CN)5L3- ＋ S2O82- ↹ Fe(CN)5L2- ＋ SO4- ＋ SO42- (1) has been interpreted on the basis of an outer-sphere electron transfer mechanism. The results k1=(2.90±0.02) 1/(sec* M)(4-Ampy )、(0.180±0.003) 1/(sec*M) (py)、(0.141±0.003) 1/(sec*M)(4,4'- bpy)、(0.0568±0.0002) 1/(sec*M)(pz)、(0.0226

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31

Merz, Beate. "Evaluierung des Aminopyrin-Atemtests bei chronischer Hepatitis C /." 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014718454&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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32

Yvonne-Chen and 陳美玲. "Acid Catalyzed Dissociation of 4-Aminopyridine Complex of Pentacyanoferrate(II)." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/17478563561798867447.

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碩士<br>東海大學<br>化學系<br>87<br>For Fe(CN)5(4-Ampy)3- complex begins to be unstable in the solutions at pH <5 is subjected to the dissociation of the complex. The rates of the dissociation as a function of acid concentration follow the saturation kinetics. The first step of the protonation of the complex which is followed by the dissociation of the prontonated species, The rate law of the reaction is -dFe(II)/dt = (kd*K*[H+]/1+K*[H+])[Fe(II)] For 2.73< pH < 5; K=(1.730.3)*103 kd=0.550.03 sec-1; For pH < 2 K=31.90.7 M-1, kd=4.920.02 sec-1. The results at higher pH values correspond

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33

Su, Tzu-Yuan, and 蘇子源. "Synthesis and Structures of Zinc(II) Compounds Containing 4-Aminopyridine." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/56aa67.

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碩士<br>中原大學<br>化學研究所<br>105<br>In this thesis, the synthesis and structures of three mononuclear Zn(II) complexes containing 4-aminopyridine (L) are discussed. The reactions of Zn(II) metal salts with L afforded three complexes, Zn(OAc)2(L)2, 1, Zn(Br)2(L)2, 2, and {[Zn(L)4][NO3]2}‧3H2O, 3, which were characterized by X-ray crystallography. The metal center of complex 1 is coordinated by two L ligands and two OAc- anions, and that of 2 is coordinated by two L ligands and two Br- anions, whereas that of 3 is coordinated by four L ligands, resulting in the similar distorted tetrahedral geometry.

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34

Tseng, Ming-Hsun, and 曾銘勳. "A Physical Study of Oligonucleotides Containing N4-(6-aminopyridin-2-yl)-2'-deoxycytidine." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/54720664168624912593.

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碩士<br>中國文化大學<br>應用化學研究所<br>88<br>Oligonucleotide-directed triple helix formation is one of the most versatile methods for the sequence-specific recognition of double helical DNA. However, both sequence-specific recognition of dsDNA appears to be limited to mostly purine tracts. Design leads to expand the recognition code to pyrimidine-purine base pair (CG and AT). We have previously shown that N4-(6-aminopyridin-2-yl)-2'-deoxycytidine (P) is able to interact with the CG base pair through hydrogen bonds to form a stable P‧CG base triad. In this thesis, the oligonucleotide P1 (5'-d-TT

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35

Li, Zong-Wei, and 李宗瑋. "Synthesis, Structures and Properties of Nickel (II) Compounds Containing 4-Aminopyridine." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/ger94z.

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碩士<br>中原大學<br>化學研究所<br>102<br>In this thesis, the structures of three nickel(II) complexes containing 4-aminopyridine, L, are discussed. The reactions of Ni(II) metal salts with L in ethanol afforded the complexes : {[NiCl(L)4]Cl}n, 1, [Ni(L)4](ClO4)2, 2, and [Ni(L)3(NO3)2] • C4H10O, 3, respectively, which were characterized by X-ray crystallography. The Ni(II) ions of 1 are coordinated by four L ligands and two chloride anions, resulting in octahedron geometries. The metal centers are also linked by the chloride anions to from 1D chins, which are further linked by the N-H---Cl hydrogen bonds

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36

Uttl, Libor. "Aktivace neuroglií po epileptickém statu vyvolaném intracerebroventrikulární aplikací 4-aminopyridinu u potkana." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-323581.

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Epilepsy is a chronic disease characterized by spontaneous epileptic seizures. One percent of the world population is affected by the epilepsy. The existence of proper models is crucial for study of distinct types of epilepsy. We decided to deeply describe the model of status epilepticus (SE) induction in an adult rat by the intracerebroventricular application of 4-aminopyridine (4-AP). For description of this model we used the histology and immunohistochemistry methods, the western blot analysis focused on the microglial activation markers, and the series of behavioral tests to reveal the fun

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37

Lin, Yu-Sheng, and 林裕盛. "Synthesis, Structure and Properties of Zinc(Ⅱ) Coordination Polymers containing 4-aminopyridine." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/80294801410635082982.

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碩士<br>中原大學<br>化學研究所<br>104<br>Two Zn(II) complexes containing 4-aminopyridine (L) and benzenedicarboxylate ligands, [Zn2(L)4(1,2-BDC)2] (1,2-H2BDC = benzene-1,2-dicarboxylic acid), 1, and {[ Zn2(L)4(1,3-BDC)2] }ｎ(1,3-H2BDC = benzene-1,3-dicarboxylic acid), 2, are reported, which were prepared by hydrothermal reactions. Their structures were determined by single crystal X-ray diffraction analyses and further characterized by elemental analyses, powder X-ray diffraction and thermal gravimetric analysis. Complex 1 is a dinuclear complex and the zinc metal center is coordinated by two pyridyl nit

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38

Ying-YuChen and 陳穎俞. "Adaptive Suppression of 4-Aminopyridine Induced Epileptiform Activity by in vivo Optogenetic Stimulation." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/33522877531763564004.

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碩士<br>國立成功大學<br>機械工程學系<br>103<br>Traditional epilepsy treatments included drug therapy, focal resection and electrical stimulation. The optogenetic stimulation is a new approach of treating epilepsy by means of light to stimulate or inhibit neural circuits via viral transduction of light sensitive proteins on the neurons. However, for the optogenetic stimulation, the mechanism of stimulation frequency to seizure state was still unknown in past studies. Therefore, in this study the effect of frequency on the suppression of seizures associated with tonic phase and clonic phase was investigated.

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39

Chen, Kung-Ting, and 陳冠廷. "Synthesis, Structures and Properties of Coordination Polymers with 4-Aminopyridine and Benzenedicarboxylate Ligands." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/61236332122823492159.

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碩士<br>中原大學<br>化學研究所<br>104<br>A series of Co(II), Ni(II) and Cu(II) coordination polymers containing 4-aminopyridine (4-ampy) and benzenedicarboxylate ligands, {[Ni(4-ampy)2(1,4-BDC)] · H2O ·CH3CH2OH}n (1,4-H2BDC = benzene-1,4-dicarboxylic acid), 1, {[Ni2(4-ampy)4(1,3-BDC)2] · H2O · CH3CH2OH}n (1,3-H2BDC = benzene-1,3-dicarboxylic acid), 2, [Ni2(4-ampy)4(1,2-BDC)2] (1,2-H2BDC = benzene-1,2-dicarboxylic acid), 3, {[Co(4-ampy)2(1,4-BDC)] · H2O ·CH3CH2OH}n, 4, {[Co(4-ampy)2(1,3-BDC)]}n, 5, [Co2(4-ampy)4(1,2-BDC)2], 6, {[Cu(4-ampy)2(1,4-BDC)] · CH3CH2OH}n, 7a, {[Cu(4-ampy)2(1,4-BDC)] · 3H2O}n, 7b,

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Chung, Kuen-Yuan, and 鍾昆元. "A Study of Triple-stranded DNA Formation of Oligouncleotides Containing N4-(6-aminopyridin-2-yl)-2'-deoxycytidine." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/04568092365709506316.

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碩士<br>中國文化大學<br>應用化學研究所<br>87<br>Oligonucleotide triple-stranded helix formation is one of the most versatile methods for the sequence-specific recognition of double helical DNA. The specificity is derived from the formation of hydrogen bonds between bases in the third strand and duplex base pairs. There are currently two classes of base triads, namely Py‧PuPy and Pu‧PuPy. Both sequence-specific recognition of dsDNA appears to be limited mostly to purine tracts. Design leads to expand the recognition code to pyrimidine-purine base pair(CG and AT). This would provide one step toward a general

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Karapanayiotis, Thanassis, G. Dimopolos-Italiano, Richard D. Bowen, and J. K. Terlouw. "Reactions of Ionised Pryridazine, 2-Aminopyrazine and 2-Aminopyridine and their a-Distonic Isomers." 2004. http://hdl.handle.net/10454/3659.

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No<br>The reactions of ionised pyridazine, aminopyrazine and aminopyridine and the corresponding ¿-distonic ions are examined by a combination of tandem mass spectrometric techniques, including analysis of metastable ion (MI), collision induced dissociation and neutralisation¿reionisation mass spectra (NRMS). Further insight into the relative stability and energy barriers towards tautomerism of each ionised heterocycle with its ¿-distonic isomer is obtained by computational methods. In all these systems, both the conventional radical-cation and the ¿-distonic tautomer are stable species which

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Franciosi, Sonia. "Beta-Amyloid₁₋₄₂- induced intracellular signaling pathways, functional responses and modulation by 4-aminopyridine in microglia." Thesis, 2005. http://hdl.handle.net/2429/18328.

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Alzheimer's Disease (AD) is a progressive, neurodegenerative disease characterized by gradual cognitive decline and memory loss. Although research has focused on elucidating the risk factors, pathophysiologic abnormalities associated with AD and on mechanisms of impeding disease progression, results indicate that a variety of factors may contribute to AD which makes treating this disease difficult. The neuropathological hallmarks of AD include senile plaques which are composed of extracellular deposits of amyloid beta (Aβ) peptide as well as neurofibrillary tangles, neuronal loss and inflammat

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Schultz, Verena. "Axonal degeneration and protection during early remyelination in multiple sclerosis and an animal model." Doctoral thesis, 2015. http://hdl.handle.net/11858/00-1735-0000-0022-5DBF-B.

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Wurzbacher, Steffen Rüdiger Josef [Verfasser]. "Der Aminopyrin-Atemtest als hepatischer Verlaufsparameter in der abdominalen Sepsis / Steffen Rüdiger Josef Wurzbacher." 2007. http://d-nb.info/988480069/34.

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LIN, RUI-SHENG, and 林瑞生. "Studies on the effects of uranyl nitrate and 4-aminopyridine on neuromuscular transmission of the mouse diaphragm." Thesis, 1986. http://ndltd.ncl.edu.tw/handle/53550160730920124785.

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"Effets de la 4-aminopyridine sur le lymphocyte T Jurkat: Influx calcique, induction de l'apoptose et permeation d'ions /." S.l. : Universite de Sherbrooke, 2004. http://proquest.umi.com/pqdweb?did=1563018731&sid=1&Fmt=2&clientId=12520&RQT=309&VName=PQD.

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ZHOU, SHU-MEI, and 周淑玫. "Anticonvulsant effects of excitatory amino acid receptor antagonists and calcium channel blockers on epileptiform activity induced by 4-aminopyridine in rat basolateral amygdala neurons." Thesis, 1991. http://ndltd.ncl.edu.tw/handle/73139030070427011679.

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Schulze, Christina [Verfasser]. "Prüfung der Leberfunktion mit Hilfe der 13C-Atemteste Aminopyrin und Methacetin bei Patienten mit einer kompletten Querschnittlähmung unterschiedlicher Höhenlokalisation / vorgelegt von Christina Schulze." 2002. http://d-nb.info/965897400/34.

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