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Relevant bibliographies by topics / Aminopyrimidine

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Academic literature on the topic 'Aminopyrimidine'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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Journal articles on the topic "Aminopyrimidine"

1

Zhao, Mingzhu, Juewang Cai, and Xiaoming Zhao. "Silver-promoted selective fluorination of 2-aminopyrimidines: synthesis of 5-fluoro-2-aminopyrimidine derivatives." Organic Chemistry Frontiers 6, no. 4 (2019): 426–31. http://dx.doi.org/10.1039/c8qo01054d.

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Ag-Promoted selective fluorination of 2-aminopyrimidine derivatives with Selectfluor is presented, giving 4-substituted 5-fluoro-2-aminopyrimidines in fair to high yields with excellent regioselectivities.

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Schlueter, John A., Russell J. Funk, and Urs Geiser. "5-Aminopyrimidine." Acta Crystallographica Section E Structure Reports Online 62, no. 1 (2005): o339—o341. http://dx.doi.org/10.1107/s1600536805042236.

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Kloda, Matouš, Irena Matulková, Ivana Císařová, et al. "Cocrystals of 2-Aminopyrimidine with Boric Acid—Crystal Engineering of a Novel Nonlinear Optically (NLO) Active Crystal." Crystals 9, no. 8 (2019): 403. http://dx.doi.org/10.3390/cryst9080403.

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Crystal engineering of novel materials for nonlinear optics (NLO) based on 2-aminopyrimidine yielded two molecular cocrystals with boric acid—trigonal (P3221 space group) 2-aminopyrimidine—boric acid (3/2) and monoclinic (C2/c space group) 2-aminopyrimidine—boric acid (1/2). In addition to crystal structure determination by single crystal X-ray diffraction, the cocrystals were characterized by powder X-ray diffraction and vibrational spectroscopy (FTIR and FT Raman). Large single crystals of the non-centrosymmetric cocrystal 2-aminopyrimidine—boric acid (3/2) were grown to study the optical pr

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Hoffelner, Michael, Usama Hassan, Werner Seebacher, et al. "New 2-aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities." Monatshefte für Chemie - Chemical Monthly 151, no. 9 (2020): 1375–85. http://dx.doi.org/10.1007/s00706-020-02674-7.

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Abstract Novel 2-aminopyrimidine derivatives were prepared from acyclic starting materials, benzylidene acetones and ammonium thiocyanates, via 5 steps, including ring closure, aromatization, S-methylation, oxidation to methylsulfonyl compounds, and formation of guanidines with suitable amines. The prepared compounds differ from each other by the substitutions of their amino group and of their phenyl ring. The 2-aminopyrimidines were tested by use of microplate assays for their in vitro activities against a causative organism of sleeping sickness, Trypanosoma brucei rhodesiense, as well as aga

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Petrova, Olga V., Arsalan B. Budaev, Elena F. Sagitova, et al. "Pyrrole–Aminopyrimidine Ensembles: Cycloaddition of Guanidine to Acylethynylpyrroles." Molecules 26, no. 6 (2021): 1692. http://dx.doi.org/10.3390/molecules26061692.

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An efficient method for the synthesis of pharmaceutically prospective pyrrole–aminopyrimidine ensembles (in up to 91% yield) by the cyclocondensation of easily available acylethynylpyrroles with guanidine nitrate has been developed. The reaction proceeds under heating (110–115 °C, 4 h) in the KOH/DMSO system. In the case of 2-benzoylethynylpyrrole, the unexpected addition of the formed pyrrole–aminopyrimidine as N- (NH moiety of the pyrrole ring) and C- (CH of aminopyrimidine) nucleophiles to the triple bond is observed.

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Manorama, Garima Awasthi. "A Overview Of The 2-Aminopyrimidine Derivatives As Antimicrobial Agents." International Journal of Pharmaceutical Sciences 2, no. 8 (2024): 2420–26. https://doi.org/10.5281/zenodo.13167948.

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The ongoing challenge of antimicrobial resistance necessitates the continuous exploration of new antimicrobial agents. Among various chemical scaffolds, 2-aminopyrimidine derivatives have garnered significant attention due to their broad-spectrum antimicrobial properties. This review provides a comprehensive overview of 2-aminopyrimidine derivatives, highlighting their chemical synthesis, structural diversity, and mechanisms of action. Emphasis is placed on recent advancements in the development of these compounds, their activity against a variety of microbial pathogens, and their potential as

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Wang, Li-Hua, Fan-Yuan Kong, and Xi-Shi Tai. "Crystal Structure and Catalytic Activity of Poly[bis(3-bromo-2-hydroxybenzaldehyde)-2-aminopyrimidinemagnesium(II)] for Hydrogenation of 1,3-Butadiene." Bulletin of Chemical Reaction Engineering & Catalysis 16, no. 2 (2021): 260–66. http://dx.doi.org/10.9767/bcrec.16.2.10421.260-266.

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A new six-coordinated Mn(II) coordination polymer, [Mn(L1)(L2)2]n (L1 = 2-aminopyrimidine, HL2 = 3-bromo-2-hydroxybenzaldehyde) was synthesized by 3-bromo-2-hydroxybenzaldehyde, NaOH, 2-aminopyrimidine and manganese(II) acetate dihydrate. The Mn(II) coordination polymer was structural characterized by elemental analysis and single crystal X-ray diffraction. The results show that each Mn(II) ion is six-coordinated with two phenolic hydroxyl O atoms from two 3-bromo-2-hydroxybenzaldehyde ligands (O1 and O4), two formyl group O atoms from two 3-bromo-2-hydroxybenzaldehyde ligands (O2 and O3), and

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Sienkiewicz-Gromiuk, Justyna, and Aleksandra Drzewiecka-Antonik. "Neutral and Ionic Form of (Benzylthio)Acetic Acid in Novel Aminopyrimidine Based Multi-Component Crystalline Phases." Crystals 13, no. 12 (2023): 1628. http://dx.doi.org/10.3390/cryst13121628.

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(benzylthio)acetic acid (HBTA) and some aminopyrimidines, namely 2-aminopyrimidine (2-AP), 5-aminopyrimidine (5-AP), 2-amino-4,6-dimethylpyrimidine (2-A-4,6-DMP), and 2,4,6-triaminopyrimidine (2,4,6-TAP), were successfully embodied as structural units into the construction of a total of four novel supramolecular organic frameworks. The received crystalline solids were inspected by single-crystal X-ray diffraction (SC XRD) in order to obtain insight into the structural and supramolecular facets. The SOFs deriving from 2-AP, 5-AP, and 2-A-4,6-DMP crystallize in the form of co-crystals (1–3), whi

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Li, Di, Rammohan R. Yadav Bheemanaboina, Narsaiah Battini, Vijai Kumar Reddy Tangadanchu, Xian-Fu Fang, and Cheng-He Zhou. "Novel organophosphorus aminopyrimidines as unique structural DNA-targeting membrane active inhibitors towards drug-resistant methicillin-resistant Staphylococcus aureus." MedChemComm 9, no. 9 (2018): 1529–37. http://dx.doi.org/10.1039/c8md00301g.

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M., SEADA, M. ABDEL-RAHMAN R., and HANAFY F. "Synthesis of some New 1,2,4-Triazines containing Aminopyrimidine Moiety." Journal of Indian Chemical Society Vol. 69, Dec 1992 (1992): 882–84. https://doi.org/10.5281/zenodo.6120238.

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Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt <em>Manuscript received 21 February 1992, revised 20 July 1992, accepted 10 August 1992</em> Synthesis of some New 1,2,4-Triazines containing Aminopyrimidine Moiety.

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Dissertations / Theses on the topic "Aminopyrimidine"

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Trinks, Uwe Peter. "Zur Chemie der Aminopyrimidine /." [S.l.] : [s.n.], 1987. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=8368.

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Haycock, Meghan Lynn. "Towards Fluorinated Substrate Analogs and N-Acylated 2-Aminopyrimidine Inhibitors of Lipoxygenases." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31520.

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Cyclooxygenase (COX) and lipoxygenase (LOX) catalyze the rate-determining step in the production of arachidonic acid- derived signaling molecules (eicosanoids) within the body. COX has been extensively investigated, which has enabled the design of non-steroidal inflammatory drugs (NSAIDs) such as aspirin, acetaminophen (ApAP) and ibuprofen. However, there are still fundamental questions surrounding the LOX family of enzymes, which has limited the development of isoform specific inhibitors. The structural basis and regio- and stereoselectivity of the LOX isoforms are not known. Herein, we desc

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Eberhard, Jens [Verfasser]. "Funktionalisierte 2-Aminopyrimidine und 2,2':6',2''-Terpyridine und ihre Koordinationsverbindungen : Synthese und optische Eigenschaften / Jens Eberhard." Bielefeld : Universitätsbibliothek Bielefeld, 2014. http://d-nb.info/1051077087/34.

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Dosière-Durand, Carine. "Approche globale pour la gestion et l'élimination des polluants organiques : application aux rejets aqueux issus des procédés de synthèses du 5007-TDS et du 12911." Paris 11, 2008. http://www.theses.fr/2008PA112263.

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L’approche globale est un concept multidisciplinaire développé au laboratoire de microbiologie appliquée depuis une dizaine d’années, dans le but de répondre à un problème industriel. Il a été appliqué, dans le cadre de cette thèse, sur des effluents aqueux rejetés lors de la synthèse de deux médicaments phares des laboratoires Servier : L’Arcalion, médicament antiasthénie et le Protelos, utilisé pour la lutte contre l’ostéoporose. La première étape du sujet concerne l’analyse et la caractérisation des polluants organiques présents dans les deux effluents étudiés. Les deux familles de polluant

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Castillo, Aguilera Omar. "Conception, synthèse et évaluation pharmacologique d’inhibiteurs potentiels de DOT1L impliqués dans la régulation épigénétique du cancer." Thesis, Lille 2, 2017. http://www.theses.fr/2017LIL2S053/document.

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Le cancer, principale cause de mortalité dans le monde, est un problème majeur de santé publique. Malgré les nombreux traitements disponibles, il est nécessaire de développer de nouvelles thérapies plus efficaces et moins envahissantes. Aujourd’hui la connaissance du génome humain a dirigé la recherche vers de nouvelles approches: il est possible de moduler la réponse biologique en contrôlant l'accès aux informations génétiques via la régulation épigénétique.L’épigénétique est l’ensemble des modifications de l’expression des gènes n’entraînant pas de modifications dans la séquence d’ADN, qui m

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Löpfe, Michael Löpfe Michael. "Synthesis of carbon-analogues of 2,4-diaminopyrimidine and 2-oxo-4-aminopyrimidine homo-DNA nucleosides : Study of homo-DNA oligonucleotides containing carbon-analogues of the 2,4-diaminopyrimidine nucleotide /." [S.l.] : [s.n.], 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000286574.

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Robinson, Sarel Johannes. "Syntheses of chalcones and 2-aminopyrimidines and their evaluation as monoamine oxidase inhibitors and as adenosine receptor antagonists / Sarel Johannes Robinson." Thesis, North-West University, 2013. http://hdl.handle.net/10394/9534.

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Background and rationale - Parkinson’s disease is a neurodegenerative disorder characterised by reduced levels of dopamine in the brain. The cause of Parkinson's disease is still unknown; however several theories pertaining to the etiology exist. Current treatment mainly aims at dopamine replacement, with agents such as levodopa and dopamine agonists that provide patients with symptomatic relief. This relief is unfortunately only temporary as the progression of the disease is not halted. Furthermore, these therapies are associated with a range of side effects and novel approaches to the treat

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8

Kloda, Matouš. "Příprava a studium nových krystalických materiálů pro nelineární optiku odvozených od dusíkatých heterocyklů." Doctoral thesis, 2019. http://www.nusl.cz/ntk/nusl-404297.

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The presented Ph.D. thesis is aimed at the preparation and characterisation of novel crystalline materials with application potential in nonlinear optics (NLO). The main goal was preparation of crystalline salts and adducts (cocrystals) of selected nitrogen-containing heterocycles with a range of organic and inorganic acids. Based on previous study and quantum- chemical calculations, the following starting heterocycles were selected: 2-aminopyrimidine, 4-aminopyrimidine, 5-aminopyrimidine, 3-amino-1,2,4-triazine and 3-amino-5,6-dimethyl- 1,2,4-triazine. The prepared materials were characterise

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Kleynhans, Janke. "Aminopyrimidine derivatives as adenosine antagonists / Janke Kleynhans." Thesis, 2013. http://hdl.handle.net/10394/10857.

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Aims of this project - The aim of this study was to design and synthesise novel 2-aminopyrimidine derivatives as potential adenosine A1 and A2A receptor antagonists. Background and rationale - Parkinson’s disease is the second most common neurodegenerative disorder (after Alzheimer’s disease) and is characterised by the selective death of the dopaminergic neurons of the nigro-striatal pathway. Distinctive motor symptoms include bradykinesia, muscle rigidity and tremor, while non-motor symptoms, of which cognitive dysfunction is an example, also frequently occur. Current therapy provides sympto

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Chu, Kuan-Lun, and 朱冠綸. "Study on Ag( I )complexes Bearing 2-Aminopyrimidine." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/6jgzms.

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碩士<br>中原大學<br>化學研究所<br>92<br>Abstract A series of silver (I) complexes of the types {[Ag2(L2)( PF6)]}∞ , 1; {[Ag2(L2)( SO4)]}∞ , 2 ; [Ag(L2)( PF6)] , 3; {[Ag(L1.5)(ClO4)]}∞, 4 ;{[Ag(L)(OAc)]}∞, 5 have been prepared by the reactions AgX(X = PF6�{ , ClO4�{ , OAc �{)and Ag2SO4 . All the complexes have been structurally characterized by X-ray crystallograply. Complexes,1、2 and 4 form two-dimensional structures while complex 3 is mononuclear,complex 5 is one-dimension Zigzag Chain.

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Book chapters on the topic "Aminopyrimidine"

1

Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex of 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-49202-4_55.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of cobalt(II) complex of 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45972-0_479.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex of 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45972-0_581.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex with dicyanamide and 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53971-2_754.

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Riefer, A., M. Rohrmüller, M. Landmann, et al. "Electronic and Optical Excitations of Aminopyrimidine Molecules from Many-Body Perturbation Theory." In High Performance Computing in Science and Engineering ‘12. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-33374-3_3.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of μ-hydroxo bridged binculear copper(II) complex with 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 4. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62474-6_216.

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Yakovlev, K. I., A. I. Stetsenko, G. M. Alekseyeva, A. A. Tulub, L. B. Selderkhanova, and I. Yu Mamelkina. "Platinum (II) Complexes with Aminopyrimidines." In Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-1717-3_91.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand copper(II) complex with Schiff-base derived from thiophene-2-glyoxal and 2-aminopyrimidine and chloride." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_254.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand copper(II) complex with Schiff-base derived from thiophene-2-glyoxal and 2-aminopyrimidine and chloride." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_255.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand copper(II) complex with Schiff-base derived from thiophene-2-glyoxal and 2-aminopyrimidine and ammonia." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_256.

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Conference papers on the topic "Aminopyrimidine"

1

Vargas, Pâmela S. de, Helio G. Bonacorso, Nilo Zanatta, Clarissa P. Frizzo, and Marcos A. P. Martins. "Microwave-assisted Synthesis of New Ethyl 2-aminopyrimidine- 4-carboxylates." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013914191433.

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De Oliveira, Eliseu O., Yongxian Ma, York Tomita, Eliot Rosen, and Milton L. Brown. "Abstract 2458: Discovery and development of novel 4-aminopyrimidines (A9 analogs) as potential BRCA1-mimetic drugs for the treatment of breast cancer." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2458.

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