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Journal articles on the topic 'Aminopyrimidine'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Zhao, Mingzhu, Juewang Cai, and Xiaoming Zhao. "Silver-promoted selective fluorination of 2-aminopyrimidines: synthesis of 5-fluoro-2-aminopyrimidine derivatives." Organic Chemistry Frontiers 6, no. 4 (2019): 426–31. http://dx.doi.org/10.1039/c8qo01054d.

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Ag-Promoted selective fluorination of 2-aminopyrimidine derivatives with Selectfluor is presented, giving 4-substituted 5-fluoro-2-aminopyrimidines in fair to high yields with excellent regioselectivities.

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2

Schlueter, John A., Russell J. Funk, and Urs Geiser. "5-Aminopyrimidine." Acta Crystallographica Section E Structure Reports Online 62, no. 1 (2005): o339—o341. http://dx.doi.org/10.1107/s1600536805042236.

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3

Kloda, Matouš, Irena Matulková, Ivana Císařová, et al. "Cocrystals of 2-Aminopyrimidine with Boric Acid—Crystal Engineering of a Novel Nonlinear Optically (NLO) Active Crystal." Crystals 9, no. 8 (2019): 403. http://dx.doi.org/10.3390/cryst9080403.

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Crystal engineering of novel materials for nonlinear optics (NLO) based on 2-aminopyrimidine yielded two molecular cocrystals with boric acid—trigonal (P3221 space group) 2-aminopyrimidine—boric acid (3/2) and monoclinic (C2/c space group) 2-aminopyrimidine—boric acid (1/2). In addition to crystal structure determination by single crystal X-ray diffraction, the cocrystals were characterized by powder X-ray diffraction and vibrational spectroscopy (FTIR and FT Raman). Large single crystals of the non-centrosymmetric cocrystal 2-aminopyrimidine—boric acid (3/2) were grown to study the optical pr

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4

Hoffelner, Michael, Usama Hassan, Werner Seebacher, et al. "New 2-aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities." Monatshefte für Chemie - Chemical Monthly 151, no. 9 (2020): 1375–85. http://dx.doi.org/10.1007/s00706-020-02674-7.

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Abstract Novel 2-aminopyrimidine derivatives were prepared from acyclic starting materials, benzylidene acetones and ammonium thiocyanates, via 5 steps, including ring closure, aromatization, S-methylation, oxidation to methylsulfonyl compounds, and formation of guanidines with suitable amines. The prepared compounds differ from each other by the substitutions of their amino group and of their phenyl ring. The 2-aminopyrimidines were tested by use of microplate assays for their in vitro activities against a causative organism of sleeping sickness, Trypanosoma brucei rhodesiense, as well as aga

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5

Petrova, Olga V., Arsalan B. Budaev, Elena F. Sagitova, et al. "Pyrrole–Aminopyrimidine Ensembles: Cycloaddition of Guanidine to Acylethynylpyrroles." Molecules 26, no. 6 (2021): 1692. http://dx.doi.org/10.3390/molecules26061692.

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An efficient method for the synthesis of pharmaceutically prospective pyrrole–aminopyrimidine ensembles (in up to 91% yield) by the cyclocondensation of easily available acylethynylpyrroles with guanidine nitrate has been developed. The reaction proceeds under heating (110–115 °C, 4 h) in the KOH/DMSO system. In the case of 2-benzoylethynylpyrrole, the unexpected addition of the formed pyrrole–aminopyrimidine as N- (NH moiety of the pyrrole ring) and C- (CH of aminopyrimidine) nucleophiles to the triple bond is observed.

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6

Manorama, Garima Awasthi. "A Overview Of The 2-Aminopyrimidine Derivatives As Antimicrobial Agents." International Journal of Pharmaceutical Sciences 2, no. 8 (2024): 2420–26. https://doi.org/10.5281/zenodo.13167948.

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The ongoing challenge of antimicrobial resistance necessitates the continuous exploration of new antimicrobial agents. Among various chemical scaffolds, 2-aminopyrimidine derivatives have garnered significant attention due to their broad-spectrum antimicrobial properties. This review provides a comprehensive overview of 2-aminopyrimidine derivatives, highlighting their chemical synthesis, structural diversity, and mechanisms of action. Emphasis is placed on recent advancements in the development of these compounds, their activity against a variety of microbial pathogens, and their potential as

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7

Wang, Li-Hua, Fan-Yuan Kong, and Xi-Shi Tai. "Crystal Structure and Catalytic Activity of Poly[bis(3-bromo-2-hydroxybenzaldehyde)-2-aminopyrimidinemagnesium(II)] for Hydrogenation of 1,3-Butadiene." Bulletin of Chemical Reaction Engineering & Catalysis 16, no. 2 (2021): 260–66. http://dx.doi.org/10.9767/bcrec.16.2.10421.260-266.

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A new six-coordinated Mn(II) coordination polymer, [Mn(L1)(L2)2]n (L1 = 2-aminopyrimidine, HL2 = 3-bromo-2-hydroxybenzaldehyde) was synthesized by 3-bromo-2-hydroxybenzaldehyde, NaOH, 2-aminopyrimidine and manganese(II) acetate dihydrate. The Mn(II) coordination polymer was structural characterized by elemental analysis and single crystal X-ray diffraction. The results show that each Mn(II) ion is six-coordinated with two phenolic hydroxyl O atoms from two 3-bromo-2-hydroxybenzaldehyde ligands (O1 and O4), two formyl group O atoms from two 3-bromo-2-hydroxybenzaldehyde ligands (O2 and O3), and

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8

Sienkiewicz-Gromiuk, Justyna, and Aleksandra Drzewiecka-Antonik. "Neutral and Ionic Form of (Benzylthio)Acetic Acid in Novel Aminopyrimidine Based Multi-Component Crystalline Phases." Crystals 13, no. 12 (2023): 1628. http://dx.doi.org/10.3390/cryst13121628.

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(benzylthio)acetic acid (HBTA) and some aminopyrimidines, namely 2-aminopyrimidine (2-AP), 5-aminopyrimidine (5-AP), 2-amino-4,6-dimethylpyrimidine (2-A-4,6-DMP), and 2,4,6-triaminopyrimidine (2,4,6-TAP), were successfully embodied as structural units into the construction of a total of four novel supramolecular organic frameworks. The received crystalline solids were inspected by single-crystal X-ray diffraction (SC XRD) in order to obtain insight into the structural and supramolecular facets. The SOFs deriving from 2-AP, 5-AP, and 2-A-4,6-DMP crystallize in the form of co-crystals (1–3), whi

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9

Li, Di, Rammohan R. Yadav Bheemanaboina, Narsaiah Battini, Vijai Kumar Reddy Tangadanchu, Xian-Fu Fang, and Cheng-He Zhou. "Novel organophosphorus aminopyrimidines as unique structural DNA-targeting membrane active inhibitors towards drug-resistant methicillin-resistant Staphylococcus aureus." MedChemComm 9, no. 9 (2018): 1529–37. http://dx.doi.org/10.1039/c8md00301g.

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10

M., SEADA, M. ABDEL-RAHMAN R., and HANAFY F. "Synthesis of some New 1,2,4-Triazines containing Aminopyrimidine Moiety." Journal of Indian Chemical Society Vol. 69, Dec 1992 (1992): 882–84. https://doi.org/10.5281/zenodo.6120238.

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Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt <em>Manuscript received 21 February 1992, revised 20 July 1992, accepted 10 August 1992</em> Synthesis of some New 1,2,4-Triazines containing Aminopyrimidine Moiety.

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11

Lumme, P. O., H. Knuuttila та E. Lindell. "Di-μ-sulfato-O:O'-bis[(2-aminopyrimidine-N1)triaquacobalt(II)] Dihydrate (1), catena-Poly[bis(2-aminopyrimidine-N1)diaquanickel(II)-μ-sulfato-O:O' 2-Aminopyrimidine] (2), (2-Aminopyrimidine-N1)pentaaquanickel(II) Sulfate 2-Aminopyrimidine (3) and catena-Poly[bis(2-aminopyrimidine-N1)aquacopper(ii)-μ-sulfato-O:O' Dihydrate] (4)". Acta Crystallographica Section C Crystal Structure Communications 52, № 1 (1996): 51–56. http://dx.doi.org/10.1107/s0108270195001338.

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12

Smith, G., JM Gentner, DE Lynch, KA Byriel, and CHL Kennard. "Molecular Cocrystals of Carboxylic Acids. XXI. The Role of Secondary Group Interactions in Adduct Formation Between 2-Aminopyrimidine and Substituted Benzoic Acids: the Crystal Structures of the Adducts With o-Phthalic Acid, o-Nitrobenzoic Acid, o-Aminobenzoic Acid and m-Aminobenzoic Acid." Australian Journal of Chemistry 48, no. 6 (1995): 1151. http://dx.doi.org/10.1071/ch9951151.

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The crystalline adducts of 2-aminopyrimidine (2-ap) with a series of mainly ortho-substituted benzoic acids, o-phthalic acid ( opht ) [(2-ap)( opht )] (1), 2-nitrobenzoic acid (2-nba) [(2-ap)(2-bna)2] (2), 2-aminobenzoic acid (2-aba) [(2-aba) [(2-ap)(2-aba)2] (3) and 3-aminobenzoic acid (3-aba) [(2-ap)(3-aba)] (4) have been prepared and their hydrogen-bonding motifs characterized by using single-crystal X-ray diffraction. The role of substituent groups in secondary associations with cocrystal formation is considered for the 2-aminopyrimidine system.

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13

Radhakrishnan, K., Namita Sharma, and Lal Mohan Kundu. "Direct synthesis of 5- and 6-substituted 2-aminopyrimidines as potential non-natural nucleobase analogues." RSC Adv. 4, no. 29 (2014): 15087–90. http://dx.doi.org/10.1039/c4ra00249k.

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14

Kwiecień, Anna, and Zbigniew Ciunik. "Stable Hemiaminals: 2-Aminopyrimidine Derivatives." Molecules 20, no. 8 (2015): 14365–76. http://dx.doi.org/10.3390/molecules200814365.

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15

Goswami, S., A. K. Mahapatra, G. D. Nigam, K. Chinnakali, H. K. Fun, and I. A. Razak. "2-Aminopyrimidine–fumaric acid cocrystal." Acta Crystallographica Section C Crystal Structure Communications 55, no. 4 (1999): 583–85. http://dx.doi.org/10.1107/s0108270198014127.

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16

Sedenkova, Kseniya N., Evgenia V. Dueva, Elena B. Averina, et al. "Synthesis and assessment of 4-aminotetrahydroquinazoline derivatives as tick-borne encephalitis virus reproduction inhibitors." Organic & Biomolecular Chemistry 13, no. 11 (2015): 3406–15. http://dx.doi.org/10.1039/c4ob02649g.

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17

Garg, Utsav, Yasser Azim, Aranya Kar, and Chullikkattil P. Pradeep. "Cocrystals/salt of 1-naphthaleneacetic acid and utilizing Hirshfeld surface calculations for acid–aminopyrimidine synthons." CrystEngComm 22, no. 17 (2020): 2978–89. http://dx.doi.org/10.1039/d0ce00106f.

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18

Dahlqvist, Alexander, Fredrik R. Zetterberg, Hakon Leffler, and Ulf J. Nilsson. "Aminopyrimidine–galactose hybrids are highly selective galectin-3 inhibitors." MedChemComm 10, no. 6 (2019): 913–25. http://dx.doi.org/10.1039/c9md00183b.

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19

Nájera, Carmen, José Miguel Sansano, and Enrique Gómez-Bengoa. "Heterocycle-based bifunctional organocatalysts in asymmetric synthesis." Pure and Applied Chemistry 88, no. 6 (2016): 561–78. http://dx.doi.org/10.1515/pac-2016-0403.

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AbstractDifferent chiral bifunctional organocatalysts derived from trans-cyclohexane-1,2-diamine bearing different types of guanidine units able to form-hydrogen bonding activation have been designed. Conformational rigid 2-aminobenzimidazoles bearing a tertiary amino group have been used in enantioselective Michael type reactions of activated methylene compounds to nitroalkenes. The C2 symmetric bis(2-aminobenzimidazole) derivatives the appropriate organocatalyst for the conjugate addition of 1,3-dicarbonyl compounds to maleimides as well as for the SN1 reaction of benzylic alcohols with carb

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20

Lynch, Daniel E., Tariq Latif, Graham Smith, Karl A. Byriel, Colin H. L. Kennard, and Simon Parsons. "Molecular Cocrystals of Carboxylic Acids. XXXI Adducts of 2-Aminopyrimidine and 3-Amino-1,2,4-triazole with Heterocyclic Carboxylic Acids." Australian Journal of Chemistry 51, no. 5 (1998): 403. http://dx.doi.org/10.1071/c97201.

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A series of molecular adducts of 2-aminopyrimidine and 3-amino-1,2,4-triazole with heterocyclic carboxylic acids have been prepared and characterized by using X-ray powder diffraction and in four cases by single-crystal X-ray diffraction methods. These four compounds are the (1 : 1) adducts of 2-aminopyrimidine with indole-3-acetic acid [(C4H5N3)(C10H9NO2)], N-methylpyrrole-2-carboxylic acid [(C4H5N3)(C6H7NO2)] and thiophen-2-carboxylic acid [(C4H5N3)(C5H4O2S)], and the (1 : 1) adduct of 3-amino-1,2,4-triazole with thiophen-2-carboxylic acid [(C2H4N4)(C5H4O2S)]. Other compounds described are t

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21

T.V., D. Prasad Rao, Veerabhadram G., and S. Sastry K. "Electrochemical reduction behaviour of N-(benzylidene)-2- aminopyrimidine." Journal of Indian Chemical Society Vol. 77, Sep 2000 (2000): 410–12. https://doi.org/10.5281/zenodo.5869710.

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Department of Chemistry, Nizam College, Osmania University, Hyderabad-500 001, India <em>Manuscript received 7 February 2000, accepted 3 March 2000</em> <em>N</em>-(Benzylidene)-2-aminopyrimidine has been found to be reduced electrochemically in higher alkaline conditions (pH 9.8-13.0) with uptake of two electrons giving <em>N</em>-(benzyl)-2-aminopyrimidine. The products from controlled potential electrolysis (CPE) at mercury pool cathode are characterized. The protonation precedes the electronation in reduction process, which is found to be diffusion-controlled and irreversible from voltamme

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22

Hu, Gang, Chu Wang, Xin Xin, et al. "Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine derivatives as potent antitumor agents." New Journal of Chemistry 43, no. 25 (2019): 10190–202. http://dx.doi.org/10.1039/c9nj02154j.

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23

Turo-Cortés, Rubén, Carlos Bartual-Murgui, Javier Castells-Gil, M. Carmen Muñoz, Carlos Martí-Gastaldo, and José Antonio Real. "Reversible guest-induced gate-opening with multiplex spin crossover responses in two-dimensional Hofmann clathrates." Chemical Science 11, no. 41 (2020): 11224–34. http://dx.doi.org/10.1039/d0sc04246c.

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Layered Hofmann-type iron(ii) coordination polymers functionalised with 5-aminopyrimidine ligands show gate-opening driven guest-exchange accompanied by drastic structural and spin-crossover modulations.

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24

Chen, Ping, Cai-xia Song, Wan-shu Wang, Xue-liang Yu, and Yu Tang. "TfOH-mediated [2 + 2 + 2] cycloadditions of ynamides with two discrete nitriles: synthesis of 4-aminopyrimidine derivatives." RSC Advances 6, no. 83 (2016): 80055–58. http://dx.doi.org/10.1039/c6ra11408c.

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25

Le Pham, Ngoc Son, Yujeong Kwon, Hyunik Shin, and Jeong-Hun Sohn. "Copper-promoted dehydrosulfurative carbon–nitrogen cross-coupling with concomitant aromatization for synthesis of 2-aminopyrimidines." RSC Advances 13, no. 1 (2023): 172–77. http://dx.doi.org/10.1039/d2ra05180j.

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Copper-promoted dehydrosulfurative C–N cross-coupling of 3,4-dihydropyrimidin-1H-2-thione with amine accompanied by concomitant aromatization to generate 2-aryl(alkyl)aminopyrimidine derivatives is described.

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26

Senbagam, R., M. Rajarajan, R. Vijayakumar, et al. "Synthesis, Spectral Correlations and Antimicrobial Activities of 2-Pyrimidine Schiff’s Bases." International Letters of Chemistry, Physics and Astronomy 53 (July 2015): 154–64. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.53.154.

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In the present study, a series of substituted (E)-N-benzylidene-2-aminopyrimidine compounds have been synthesized by condensation reaction with 2-aminopyrimidine and meta- and para- substituted benzaldehydes. These synthesized Schiff’s base compounds are confirmed by their physical constants, UV, IR and NMR spectral data. All the observed UV absorption maximum λmax(nm), IR frequencies νC=N(cm-1), NMR δ(ppm) of C-H & C=N chemical shifts have been correlated with Hammett substituent constants and F and R parameters using single and multi-linear regression analyses in order to study the effec

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27

Senbagam, R., M. Rajarajan, R. Vijayakumar, et al. "Synthesis, Spectral Correlations and Antimicrobial Activities of 2-Pyrimidine Schiff’s Bases." International Letters of Chemistry, Physics and Astronomy 53 (July 1, 2015): 154–64. http://dx.doi.org/10.56431/p-4w6n3u.

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In the present study, a series of substituted (E)-N-benzylidene-2-aminopyrimidine compounds have been synthesized by condensation reaction with 2-aminopyrimidine and meta- and para- substituted benzaldehydes. These synthesized Schiff’s base compounds are confirmed by their physical constants, UV, IR and NMR spectral data. All the observed UV absorption maximum λmax(nm), IR frequencies νC=N(cm-1), NMR δ(ppm) of C-H & C=N chemical shifts have been correlated with Hammett substituent constants and F and R parameters using single and multi-linear regression analyses in order to study the effec

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28

Van Meervelt, L., and K. Uytterhoeven. "Crystal structure of 4-aminopyrimidine, C4H5N3." Zeitschrift für Kristallographie - New Crystal Structures 218, no. 4 (2003): 481–82. http://dx.doi.org/10.1524/ncrs.2003.218.4.481.

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29

Meervelt, L. Van, and K. Uytterhoeven. "Crystal structure of 4-aminopyrimidine, C4H5N3." Zeitschrift für Kristallographie - New Crystal Structures 218, JG (2003): 513–14. http://dx.doi.org/10.1524/ncrs.2003.218.jg.513.

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30

Lin, Zhi-Dong, та Wen Zeng. "Bis(2-aminopyrimidine-κN1)dichloridozinc(II)". Acta Crystallographica Section E Structure Reports Online 63, № 6 (2007): m1597. http://dx.doi.org/10.1107/s1600536807021575.

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31

Orlov, A. P., T. P. Trofimova, E. Yu Osipova, A. N. Proshin, and M. A. Orlova. "Zinc-containing derivatives of 2-aminopyrimidine." Russian Chemical Bulletin 66, no. 10 (2017): 1860–66. http://dx.doi.org/10.1007/s11172-017-1958-6.

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32

Qu, Yang, Shi Ming Zhang, Xian Zong Wu, Huan Zhang та Zhi Dong Lin. "Bis(2-aminopyrimidine-κN1)dibromidozinc(II)". Acta Crystallographica Section E Structure Reports Online 64, № 5 (2008): m732. http://dx.doi.org/10.1107/s1600536808006466.

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33

Savall, Brad M., Laurent Gomez, Frank Chavez, et al. "Tricyclic aminopyrimidine histamine H4 receptor antagonists." Bioorganic & Medicinal Chemistry Letters 21, no. 21 (2011): 6577–81. http://dx.doi.org/10.1016/j.bmcl.2011.08.014.

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34

Ling, Gang, Jingzhu Chen, and Shiwei Lu. "Synthesis of Substituted Heterocyclic Ureas by Selenium-Catalysed Carbonylation using Carbon Monoxide." Journal of Chemical Research 2003, no. 7 (2003): 442–44. http://dx.doi.org/10.3184/030823403103174461.

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A series of commercially useful substituted heterocyclic ureas have been synthesised via selenium-catalysed reductive carbonylation of substituted nitrobenzezes with aminopyridine or aminopyrimidine derivatives as co-reagents and carbon monoxide as carbonylating reagent.

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35

Desmond, Féilim, John F. Gallagher, and Niall Hehir. "Two acyclic imides: 3-bromo-N-(3-bromobenzoyl)-N-(pyridin-2-yl)benzamide and 3-bromo-N-(3-bromobenzoyl)-N-(pyrimidin-2-yl)benzamide." Acta Crystallographica Section E Crystallographic Communications 76, no. 12 (2020): 1800–1804. http://dx.doi.org/10.1107/s2056989020014413.

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The title compounds, C19H12Br2N2O2 and C18H11Br2N3O2, were synthesized in good yields from condensation reactions of 3-bromobenzoyl chloride with 2-aminopyridine or 2-aminopyrimidine using standard condensation reaction conditions and subsequent column chromatography.

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36

M., SEADA, M. ABDEL-RAHMAN R., and HANAFY F. "Synthesis of some New 1 ,2,4--Triazines containing Aminopyrimidine Moiety." Journal of Indian Chemical Society Vol. 69, Dec 1992 (1992): 882–84. https://doi.org/10.5281/zenodo.6033424.

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Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt <em>Manuscript r eceived 21 February 1992, revised 20 July 1992, accepted 10 August 1992</em> Synthesis of some New 1 ,2,4--Triazines containing Aminopyrimidine Moiety.  

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37

Etter, M. C., D. A. Adsmond, and D. Britton. "2-Aminopyrimidine–succinic acid (1/1) cocrystal." Acta Crystallographica Section C Crystal Structure Communications 46, no. 5 (1990): 933–34. http://dx.doi.org/10.1107/s010827018901365x.

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38

Goswami, S., A. K. Mahapatra, K. Ghosh, G. D. Nigam, K. Chinnakali, and H. K. Fun. "2-Aminopyrimidine–terephthalic acid (1:1) complex." Acta Crystallographica Section C Crystal Structure Communications 55, no. 1 (1999): 87–89. http://dx.doi.org/10.1107/s0108270198010749.

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39

Zhu, Hai-Liang, Song Yang, Ji-Long Ma, Xiao-Yang Qiu, Lin Sun, and Si-Chang Shao. "Bis(2-aminopyrimidine)silver(I) trifluoromethanesulfonate hemihydrate." Acta Crystallographica Section E Structure Reports Online 59, no. 11 (2003): m1046—m1047. http://dx.doi.org/10.1107/s1600536803022141.

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40

Akyuz, Sevim, and Tanil Akyuz. "Vibrational spectroscopic study of 4-aminopyrimidine complexes." Journal of Molecular Structure 924-926 (April 2009): 37–41. http://dx.doi.org/10.1016/j.molstruc.2009.01.023.

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41

Serafin, Mateusz F., and Kraig A. Wheeler. "2-Aminopyrimidine–3,3,3-triphenylpropanoic acid (1/1)." Acta Crystallographica Section C Crystal Structure Communications 63, no. 11 (2007): o620—o621. http://dx.doi.org/10.1107/s0108270107045799.

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42

Sedova, V. F., and V. P. Mamaev. "6-Aminopyrimidine 1-oxides. Acylation and methylation." Chemistry of Heterocyclic Compounds 22, no. 11 (1986): 1236–41. http://dx.doi.org/10.1007/bf00471809.

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43

Savall, Brad M., and et al et al. "ChemInform Abstract: Tricyclic Aminopyrimidine Histamine H4Receptor Antagonists." ChemInform 43, no. 9 (2012): no. http://dx.doi.org/10.1002/chin.201209178.

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44

Zhu, Fang, Yujie Wang, Qian Du, et al. "Structural optimization of aminopyrimidine-based CXCR4 antagonists." European Journal of Medicinal Chemistry 187 (February 2020): 111914. http://dx.doi.org/10.1016/j.ejmech.2019.111914.

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45

Yang, H. L., S. Yang, X. Y. Qiu, et al. "Crystal structure of bis(2-aminopyrimidine)silver(I) hexafluoroarsenate bis(2-aminopyrimidine) solvate, [Ag(C4H5N3)2]AsF6 · 2C4H5N3." Zeitschrift für Kristallographie - New Crystal Structures 219, no. 1-4 (2004): 167–68. http://dx.doi.org/10.1524/ncrs.2004.219.14.167.

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46

Yang, H. L., S. Yang, X. Y. Qiu, et al. "Crystal structure of bis(2-aminopyrimidine)silver(I) hexafluoroarsenate bis(2-aminopyrimidine) solvate, [Ag(C4H5N3)2]AsF6 · 2C4H5N3." Zeitschrift für Kristallographie - New Crystal Structures 219, no. 2 (2004): 157–58. http://dx.doi.org/10.1524/ncrs.2004.219.2.157.

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Abstract C16H20AgAsF6N12, triclinic, P1̅ (no. 2), a = 7.004(1) Å, b = 8.696(2) Å, c = 11.006(2) Å, α = 68.95(3)°, β = 76.49(3)°, γ = 81.90(3)°, V = 607.1 Å3, Z = 1, Rgt(F) = 0.044, wRref(F2) = 0.111, T = 293 K.

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47

Xu, Shaoyu, Baijiao An, Yuxin Li, Xunbang Luo, Xingshu Li, and Xian Jia. "Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors." Bioorganic & Medicinal Chemistry Letters 28, no. 10 (2018): 1769–75. http://dx.doi.org/10.1016/j.bmcl.2018.04.026.

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Ramírez, Juan, Braulio Insuasty, Justo Cobo, and Christopher Glidewell. "(8RS)-4-Amino-6-(4-chlorophenyl)-8-(2,4-dichlorothiazol-5-yl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepineN,N-dimethylformamide monosolvate: sheets built from N—H...N and C—H...O hydrogen bonds." Acta Crystallographica Section C Structural Chemistry 70, no. 6 (2014): 536–40. http://dx.doi.org/10.1107/s2053229614008936.

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In the title compound, C16H11Cl3N6S·C3H7NO, the seven-membered ring adopts a conformation which is close to the twist-boat form. The molecular components are linked into sheets by a combination of two N—H...N hydrogen bonds and two C—H...O hydrogen bonds. Comparisons are made with other aminopyrimidine derivatives.

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Yeşilel, Okan Zafer, Halis Ölmez, Hümeyra Paşaoğlu, Gökhan Kaştaş, and Orhan Büyükgüngör. "Synthesis, Spectral, Thermal and Structural Characterization of the Copper(II) Saccharinato Complex of 2–Aminopyrimidine, [Cu(sac–O)2(ampym–N)2(H2O)2]·2ampym." Zeitschrift für Naturforschung B 61, no. 2 (2006): 153–58. http://dx.doi.org/10.1515/znb-2006-0206.

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AbstractBis(2-aminopyrimidine-N)diaquabis(saccharinato-O)copper(II) di(2-aminopyrimidine), [Cu(sac-O)2(ampym-N)2(H2O)2] · 2ampym was synthesized and characterized by means of elemental analysis, IR and UV-vis spectroscopy, magnetic susceptibility, simultaneous TG, DTG, DTA techniques, and X-ray diffraction. The complex crystallizes in the monoclinic space group P21/c [a = 7.4697(5), b = 10.1679(5), c = 22.743(2)Å , β = 92.844(5), Z = 2, R = 0.0275, wR= 0.0757, V = 1725.26(19) Å3]. The copper atom is bonded to two ampym N atoms and two sac O atoms as well as to two water O atoms in trans positi

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Jiao, Jingjing, Li Dou, Huimin Liu, et al. "An aminopyrimidine-functionalized cage-based metal–organic framework exhibiting highly selective adsorption of C2H2 and CO2 over CH4." Dalton Transactions 45, no. 34 (2016): 13373–82. http://dx.doi.org/10.1039/c6dt02150f.

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Abstract:

An aminopyrimidine-functionalized cage-based metal–organic framework has been synthesized, which exhibited exceptionally high C<sub>2</sub>H<sub>2</sub> and CO<sub>2</sub> uptake as well as impressive adsorption selectivities towards C<sub>2</sub>H<sub>2</sub> and CO<sub>2</sub> over CH<sub>4</sub>.

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