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Relevant bibliographies by topics / Aminothiazole Derivatives

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Academic literature on the topic 'Aminothiazole Derivatives'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Aminothiazole Derivatives"

1

Farouk Elsadek, Mohamed, Badreldin Mohamed Ahmed, and Mohamed Fawzi Farahat. "An Overview on Synthetic 2-Aminothiazole-Based Compounds Associated with Four Biological Activities." Molecules 26, no. 5 (2021): 1449. http://dx.doi.org/10.3390/molecules26051449.

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Amongst sulfur- and nitrogen-containing heterocyclic compounds, the 2-aminothiazole scaffold is one of the characteristic structures in drug development as this essential revelation has several biological activities abiding it to act as an anticancer, antioxidant, antimicrobial and anti-inflammatory agent, among other things. Additionally, various 2-aminothiazole-based derivatives as medical drugs have been broadly used to remedy different kinds of diseases with high therapeutic influence, which has led to their wide innovations. Owing to their wide scale of biological activities, their struct

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2

Tejashree, Deokule. "1,3,4-Thiadiazole and its Derivatives: A Versatile Moiety." Medicinal Chemistry 13, no. 1 (2023): 9. https://doi.org/10.37421/2161-0444.2023.13.660.

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The evaluation of thiazole's biological activity, such as antibacterial, antiprotozoal, antitubercular, antifungal and anthelmintic, with an emphasis on their potential medicinal applications, is desirable because the thiazole has an important component effect on the pharmacophores of a large number of medicinally significant molecules. We are particularly interested in investigating newly synthesized aminothiazoles, particularly 2-aminothiazole derivatives, a class of heterocyclic ring systems with antiviral, antimicrobial, anticancer and anti-inflammatory properties, respectively. Numerous h

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3

Yarosh, N. O., I. A. Dorofeev, and L. V. Zhilitskaya. "Organosilicon derivatives based on 2-aminothiazolium cations." Журнал органической химии 59, no. 5 (2023): 588–95. http://dx.doi.org/10.31857/s051474922305004x.

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The reactions of 2-aminothiazole and 2-aminobenzothiazole with (iodomethyl) derivatives of silanes in the absence of a base gave the previously unknown organosilicon salts and ionic liquids of 2-aminothiazole and 2-aminobenzothiazole. Structure of the obtained compounds was proved by NMR, and UV spectroscopy methods.

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4

Farzaliyev, V. M., M. T. Abbasova, B. G. Babaeva, et al. "N-ALKOXYMETHYL DERIVATIVES OF 2-AMINOTHIAZOLE AND THEIR PROTECTIVE PROPERTIES." Chemical Problems 18, no. 4 (2020): 427–35. http://dx.doi.org/10.32737/2221-8688-2020-4-427-435.

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Conditions for alkoxymethylation of 2-aminothiazole with semiformals obtained by the interaction of aliphatic alcohols with formaldehyde were worked out. Alkoxymethylation was performed by means of preliminary preparation of the semiformal of appropriate hydroxylcontaining compounds followed by interaction of semiformal with equimolar amount of 2- aminothiazole. The structure of the obtained compounds was acknowledged by means of IR and NMR 1 H spectroscopy. It was established that the reaction of the alkoxymethylation proceeds in the amino form of the starting 2-aminothiazole to form an appro

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5

Abdulhadi, Shayma L., Maadh Q. Abdulkadir, and May M. Al-Mudhafar. "The Importance of 2-AminoThiazole Schiff Bases as Antimicrobial and Anticancer Agents." Al-Mustansiriyah Journal of Science 31, no. 3 (2020): 46. http://dx.doi.org/10.23851/mjs.v31i3.865.

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The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.

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6

Minickaitė, Rūta, Birutė Grybaitė, Rita Vaickelionienė, et al. "Synthesis of Novel Aminothiazole Derivatives as Promising Antiviral, Antioxidant and Antibacterial Candidates." International Journal of Molecular Sciences 23, no. 14 (2022): 7688. http://dx.doi.org/10.3390/ijms23147688.

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It is well-known that thiazole derivatives are usually found in lead structures, which demonstrate a wide range of pharmacological effects. The aim of this research was to explore the antiviral, antioxidant, and antibacterial activities of novel, substituted thiazole compounds and to find potential agents that could have biological activities in one single biomolecule. A series of novel aminothiazoles were synthesized, and their biological activity was characterized. The obtained results were compared with those of the standard antiviral, antioxidant, antibacterial and anticancer agents. The c

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7

Zav'yalov, S. I., N. E. Kravchenko, G. I. Ezhova, L. B. Kulikova, A. G. Zavozin, and O. V. Dorofeeva. "Synthesis of 2-aminothiazole derivatives." Pharmaceutical Chemistry Journal 41, no. 2 (2007): 105–8. http://dx.doi.org/10.1007/s11094-007-0023-4.

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8

Pattan, S. R., S. H. Kale, R. A. Mali, et al. "SYNTHESIS AND EVALUATION OF SOME SUBSTITUTED 2-AMINOTHIAZOLE DERIVATIVES FOR THEIR ANTITUBERCULAR, ANTIMICROBIAL & ANTIFUNGAL ACTIVITY." INDIAN DRUGS 49, no. 01 (2012): 24–32. http://dx.doi.org/10.53879/id.49.01.p0024.

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Millions of people are affected by infectious diseases caused by micro-organisms. Further the widespread microbial resistance had renewed the interest in quest for new antitubercular, antimicrobial & antifungal agents. The present study deals with synthesis & evaluation of some substituted 2-aminothiazole derivatives for their antitubercular, antimicrobial and antifungal activity. 2-aminothiazole derivatives were synthesized by treating substituted acetophenones with thiourea in presence of bromine to give 2-amino 4-substituted phenylthizole and then further treated with chloracetyl ch

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9

Samadhiya, Pushkal, Ritu Sharma, Santosh Srivastava, and Savitri Srivastava. "Synthesis of 2-oxo-azetidine derivatives of 2-amino thiazole and their biological activity." Journal of the Serbian Chemical Society 77, no. 5 (2012): 599–605. http://dx.doi.org/10.2298/jsc110616002s.

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A new series of N-[2-(2-aminothiazolyl)ethyl]-4-(substitutedphenyl)- 3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-m) have been synthesized from 2-aminothiazole as a starting material. The structure of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H NMR, 13C NMR and FAB-Mass. All the final synthesized compounds 4(a-m) were screened for their antibacterial and antifungal activities against some selected bacteria and fungi and antitubercular activity screened against M. tuberculosis with their MIC value. Antiinflammatory activity screened against al

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10

Uchikawa, Osamu, Kohji Fukatsu, and Tetsuya Aono. "Aminothiazole derivatives.I.A convenient synthesis of monocyclic and condensed 5-aminothiazole derivatives." Journal of Heterocyclic Chemistry 31, no. 4 (1994): 877–87. http://dx.doi.org/10.1002/jhet.5570310432.

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Book chapters on the topic "Aminothiazole Derivatives"

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Filipowska, Anna, Wojciech Filipowski, and Ewaryst Tkacz. "Study of Structure-Cytotoxicity Relationships of Thiourea Derivatives Containing the 2-Aminothiazole Moiety." In Innovations in Biomedical Engineering. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-47154-9_32.

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Barone, R., M. Chanon, and R. Gallo. "Aminothiazoles and Their Derivatives." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187067.ch2.

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Cailler, Lucie P., Alexander G. Martynov, Yulia G. Gorbunova, Aslan Yu Tsivadze, and Alexander B. Sorokin. "Carbene insertion to N–H bonds of 2-aminothiazole and 2-amino-1,3,4-thiadiazole derivatives catalyzed by iron phthalocyanine." In Porphyrin Science by Women. WORLD SCIENTIFIC, 2021. http://dx.doi.org/10.1142/9789811223556_0106.

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Conference papers on the topic "Aminothiazole Derivatives"

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Naz, Shagufta, Humaira Nadeem, sadia sarwar, Rehan Z. Paracha, Jun Q. Yu, and Fazlul Huq. "Abstract 1967: Synthesis, in vitro evaluation in ovarian cancer cells and molecular modeling analysis of novel 2-aminothiazole and 2-aminopyridine derivatives." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1967.

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