Relevant bibliographies by topics / Among 32 strains of Staphylococcus aureus / Journal articles
To see the other types of publications on this topic, follow the link: Among 32 strains of Staphylococcus aureus.

Journal articles on the topic 'Among 32 strains of Staphylococcus aureus'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Among 32 strains of Staphylococcus aureus.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Pazlarová, J., S. Purkrtová, J. Babulíková, and K. Demnerová. "Effects of ampicillin and vancomycin on Staphylococcus aureus biofilms." Czech Journal of Food Sciences 32, No. 2 (2014): 137–44. http://dx.doi.org/10.17221/156/2013-cjfs.

Full text
Abstract:
The collection of 23 coagulase-positive Staphylococcus aureus strains isolated mainly from food in the Czech Republic were tested on the ability to form biofilms in the presence of ampicillin and vancomycin. The antimicrobial sensitivity (16 antibiotics) was determined in all strains by the standard disc diffusion method on Mueller-Hinton agar plates (NCCLS). The resistance to ampicillin was found in 16 strains (69.5%), all strains being susceptible to vancomycin. The formation of biofilm was conducted in 96-well, polystyrene microtiter plates COSTAR 3797 in tryptic soy broth (TSB) wi
APA, Harvard, Vancouver, ISO, and other styles
2

Castanheira, Mariana, Amy A. Watters, Jan M. Bell, John D. Turnidge, and Ronald N. Jones. "Fusidic Acid Resistance Rates and Prevalence of Resistance Mechanisms among Staphylococcus spp. Isolated in North America and Australia, 2007-2008." Antimicrobial Agents and Chemotherapy 54, no. 9 (2010): 3614–17. http://dx.doi.org/10.1128/aac.01390-09.

Full text
Abstract:
ABSTRACT Among 4,167 Staphylococcus aureus and 790 coagulase-negative Staphylococcus (CoNS; not S. saprophyticus) isolates collected consecutively from North American and Australian hospitals, only 87 (1.7% overall) isolates displayed a fusidic acid (FA; also known as CEM-102) MIC of ≥2 μg/ml (FA resistance). These strains were further evaluated with a multiplex PCR to amplify the acquired resistance genes fusB, fusC, and fusD. Mutations in fusA and fusE were evaluated in all isolates showing an absence of acquired resistance genes and/or showing FA MIC values of ≥64 μg/ml. S. aureus resistanc
APA, Harvard, Vancouver, ISO, and other styles
3

Drougka, E., A. Foka, D. Posantzis, et al. "Human Staphylococcus aureus lineages among Zoological Park residents in Greece." Open Veterinary Journal 5, no. 2 (2015): 148. http://dx.doi.org/10.5455/ovj.2015.v5.i2.p148.

Full text
Abstract:
Staphylococcus aureus is a part of the microbiota flora in many animal species. The clonal spread of S. aureus among animals and personnel in a Zoological Park was investigated. Samples were collected from colonized and infected sites among 32 mammals, 11 birds and eight humans. The genes mecA, mecC, lukF/lukS-PV (encoding Panton-Valentine leukocidin, PVL) and tst (toxic shock syndrome toxin-1) were investigated by PCR. Clones were defined by Multilocus Sequence Typing (MLST), spa type and Pulsed-Field Gel Electrophoresis (PFGE). Seven S. aureus isolates were recovered from four animals and on
APA, Harvard, Vancouver, ISO, and other styles
4

Lina, Gerard, Alain Quaglia, Marie-Elisabeth Reverdy, Roland Leclercq, François Vandenesch, and Jerome Etienne. "Distribution of Genes Encoding Resistance to Macrolides, Lincosamides, and Streptogramins among Staphylococci." Antimicrobial Agents and Chemotherapy 43, no. 5 (1999): 1062–66. http://dx.doi.org/10.1128/aac.43.5.1062.

Full text
Abstract:
ABSTRACT The relative frequency of 10 determinants of resistance to macrolides, lincosamides, and streptogramins was investigated by PCR in a series of 294 macrolide-, lincosamide-, and/or streptogramin-resistant clinical isolates of Staphylococcus aureus and coagulase-negative staphylococci isolated in 1995 from 32 French hospitals. Resistance was mainly due to the presence ofermA or ermC genes, which were detected in 259 strains (88%), in particular those resistant to methicillin (78% of the strains). Macrolide resistance due to msrA was more prevalent in coagulase-negative staphylococci (14
APA, Harvard, Vancouver, ISO, and other styles
5

D'AMICO, DENNIS J., and CATHERINE W. DONNELLY. "Characterization of Staphylococcus aureus Strains Isolated from Raw Milk Utilized in Small-Scale Artisan Cheese Production." Journal of Food Protection 74, no. 8 (2011): 1353–58. http://dx.doi.org/10.4315/0362-028x.jfp-10-533.

Full text
Abstract:
Staphylococcus aureus is an important agent of bacterial mastitis in milking animals and of foodborne intoxication in humans. The purpose of this study was to examine the genetic and phenotypic diversity, enterotoxigenicity, and antimicrobial resistance of S. aureus strains isolated from raw milk used for the production of artisan cheese in Vermont. Cross-tabulations revealed that the 16 ribotypes identified among the 90 milk isolates examined were typically associated with a specific animal species and that more than half of these ribotypes were unique to individual farms. In general, specifi
APA, Harvard, Vancouver, ISO, and other styles
6

Kotzamanidis, Charalampos, George Vafeas, Virginia Giantzi, et al. "Staphylococcus aureus Isolated from Ruminants with Mastitis in Northern Greece Dairy Herds: Genetic Relatedness and Phenotypic and Genotypic Characterization." Toxins 13, no. 3 (2021): 176. http://dx.doi.org/10.3390/toxins13030176.

Full text
Abstract:
Staphylococcus aureus is the most common mastitis-related pathogen in dairy cattle, goats, and sheep worldwide. However, the population structure and genomic characteristics of mastitis-associated S. aureus in small ruminants are limited. Furthermore, the genotypic and phenotypic characteristics involved in the pathogenicity of S. aureus have been thoroughly defined, yet their association with the severity of mastitis is not fully established. Here, we performed genotyping by pulsed-field gel electrophoresis (PFGE) and spa analyses to assess the genetic diversity and relatedness of 162 S. aure
APA, Harvard, Vancouver, ISO, and other styles
7

Soleha, Tri Umiana, Sutyarso Sutyarso, Asep Sukohar, Sumardi Sumardi, and Sutopo Hadi. "Identification of vanA gene on Vancomycin-Resistant Staphylococcus aureus from Diabetic Ulcer Isolate at Lampung Province." Biomedical and Pharmacology Journal 17, no. 1 (2024): 409–16. http://dx.doi.org/10.13005/bpj/2868.

Full text
Abstract:
Staphylococcus aureus is a type of bacteria that causes an increasing number of infections in hospitals, particularly in diabetic ulcers. Over the last few decades, there has been an alarming increase in the prevalence of pathogen strains of Staphylococcus aureus resistant to antibiotics such as Vancomycin. This study aimed to identify the presence of the vanA gene, which is responsible for the mode of Vancomycin resistance in Staphylococcus aureus Lampung isolate. Ulcer swab was collected from 32 patients with ulcer complications from surgical Installation, Internal Medicine, Home Diabetes Wo
APA, Harvard, Vancouver, ISO, and other styles
8

Gordinskaya, Nataliya A., E. V. Belyaeva, E. V. Boriskina, and D. V. Kryazhev. "Antimicrobial resistance of staphylococci in pediatric hospitals." Clinical Microbiology and Antimicrobial Chemotherapy 22, no. 4 (2020): 272–75. http://dx.doi.org/10.36488/cmac.2020.4.272-275.

Full text
Abstract:
Objective. To determine frequency of Staphylococcus isolation and antimicrobial resistance in hospitalized children with different types of infections. Materials and Methods. Species identification and antimicrobial susceptibility testing in staphylococci were performed on a WalkAway 96 analyzer using Pos Combo type 20 tablets, and mecA gene detection was performed on a RotorGene 6000 amplifier with a set of AmpliSens MRSA-screen FL. Results. A total of 876 strains of staphylococci isolated in children’s hospitals were tested. The species and antibiotic resistance of Staphylococcus aureus and
APA, Harvard, Vancouver, ISO, and other styles
9

LOETO, DANIEL, M. I. MATSHEKA, and B. A. GASHE. "Enterotoxigenic and Antibiotic Resistance Determination of Staphylococcus aureus Strains Isolated from Food Handlers in Gaborone, Botswana." Journal of Food Protection 70, no. 12 (2007): 2764–68. http://dx.doi.org/10.4315/0362-028x-70.12.2764.

Full text
Abstract:
The prevalence, antibiotic resistance, and enterotoxigenic potential of Staphylococcus aureus strains from different anatomical sites on food handlers in Gaborone, Botswana, were determined. Of a total of 200 food handlers tested, 115 (57.5%) were positive for S. aureus. Of the 204 S. aureus isolates, 63 (30.9%), 91 (44.6%), and 50 (24.5%) were isolated from the hand, nasal cavity, and face, respectively, and 43 (21%) of the isolates were enterotoxigenic. The most prevalent enterotoxin was type A, which accounted for 34.9% of all the enterotoxigenic strains, and enterotoxin D was produced by t
APA, Harvard, Vancouver, ISO, and other styles
10

Vyletělová, M., H. Vlková, and I. Manga. "Occurrence and characteristics of methicillin resistant Staphylococcus aureus and methicillin resistant coagulase-negative staphylococci in raw milk manufacturing." Czech Journal of Food Sciences 29, Special Issue (2012): S11—S16. http://dx.doi.org/10.17221/4443-cjfs.

Full text
Abstract:
For monitoring the occurrence of MRSA (methicillin resistant Staphylococcus aureus) and MR-CNS (methicillin resistant coagulase-negative staphylococci), cow’s, goat’s, and sheep’s milks (bulk milks and individual samples) were investigated. Human nasal and throat swabs of the farm staff and nasal swabs of animals were also investigated as well. In total 1729 samples were examined and 634 strains were isolated by means of the cultivation method and used in this study. Generic identification of the staphylococci isolates was done performed by biochemical tests and a
APA, Harvard, Vancouver, ISO, and other styles
11

Simor, Andrew E., Tammy L. Stuart, Lisa Louie, et al. "Mupirocin-Resistant, Methicillin-Resistant Staphylococcus aureus Strains in Canadian Hospitals." Antimicrobial Agents and Chemotherapy 51, no. 11 (2007): 3880–86. http://dx.doi.org/10.1128/aac.00846-07.

Full text
Abstract:
ABSTRACT Mupirocin resistance in Staphylococcus aureus is increasingly being reported in many parts of the world. This study describes the epidemiology and laboratory characterization of mupirocin-resistant methicillin-resistant S. aureus (MRSA) strains in Canadian hospitals. Broth microdilution susceptibility testing of 4,980 MRSA isolates obtained between 1995 and 2004 from 32 Canadian hospitals was done in accordance with CLSI guidelines. The clinical and epidemiologic characteristics of strains with high-level mupirocin resistance (HLMupr) were compared with those of mupirocin-susceptible
APA, Harvard, Vancouver, ISO, and other styles
12

Cui, Mingquan, Hejia Wang, Zekun Li, et al. "Phenotypic and Molecular Characterization of Staphylococcus aureus in Dairy Farms from Henan Province and the Inner Mongolia Autonomous Region, China." Microorganisms 12, no. 11 (2024): 2150. http://dx.doi.org/10.3390/microorganisms12112150.

Full text
Abstract:
Staphylococcus aureus, a prevalent pathogen associated with infectious and foodborne diseases, is also a significant cause of intramammary infections in dairy farms. This study aimed to determine the phenotypic and molecular characterization of S. aureus in two different stock sizes of dairy farms in Henan province (HN) and the Inner Mongolia autonomous region (IM), China, through biofilm formation, antimicrobial resistance, virulence, and molecular type of S. aureus isolates. In HN, 74 S. aureus isolates (60.7%) were recovered from 122 bulk tank milk samples, while in IM, 24 S. aureus isolate
APA, Harvard, Vancouver, ISO, and other styles
13

Rodríguez, Martha Fabiola, Arlen Patricia Gomez, and Andres Ceballos-Garzon. "Antimicrobial Resistance Profiles of Staphylococcus Isolated from Cows with Subclinical Mastitis: Do Strains from the Environment and from Humans Contribute to the Dissemination of Resistance among Bacteria on Dairy Farms in Colombia?" Antibiotics 12, no. 11 (2023): 1574. http://dx.doi.org/10.3390/antibiotics12111574.

Full text
Abstract:
Staphylococcus is a very prevalent etiologic agent of bovine mastitis, and antibiotic resistance contributes to the successful colonization and dissemination of these bacteria in different environments and hosts on dairy farms. This study aimed to identify the antimicrobial resistance (AMR) genotypes and phenotypes of Staphylococcus spp. isolates from different sources on dairy farms and their relationship with the use of antibiotics. An antimicrobial susceptibility test was performed on 349 Staphylococcus strains (S. aureus, n = 152; non-aureus staphylococci (NAS), n = 197) isolated from quar
APA, Harvard, Vancouver, ISO, and other styles
14

Ahmad, Pishtiwan. "PHENOTYPIC AND MOLECULAR DETECTION OF BIOFILM FORMATION IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ISOLATED FROM DIFFERENT CLINICAL SOURCE IN ERBIL CITY." Mediterranean Journal of Hematology and Infectious Diseases 15, no. 1 (2023): e2023016. http://dx.doi.org/10.4084/mjhid.2023.016.

Full text
Abstract:
Abstract.
 Background: Staphylococcus aureus is an important causative pathogen. The production of biofilms is an important factor and makes these bacteria resistant to antimicrobial therapy.
 Objectives: the current study aimed to assess the prevalence of resistance to antibacterial agents and to evaluate the phenotypic and genotypic characterization of biofilm formation among S. aureus strains.
 Methods: In this study, 50 isolates of Methicillin-resistant S. aureus (MRSA) and Methicillin-Susceptible S. aureus (MSSA) were included. S. aureus was identified by molecular and conv
APA, Harvard, Vancouver, ISO, and other styles
15

HATAKKA, M., K. J. BJÖRKROTH, K. ASPLUND, N. MÄKI-PETÄYS, and H. J. KORKEALA. "Genotypes and Enterotoxicity of Staphylococcus aureus Isolated from the Hands and Nasal Cavities of Flight-Catering Employees." Journal of Food Protection 63, no. 11 (2000): 1487–91. http://dx.doi.org/10.4315/0362-028x-63.11.1487.

Full text
Abstract:
Hand and nasal samples of flight-catering staff were collected from 1995 to 1997 to find employees carrying Staphylococcus aureus. Altogether 153 hand samples and 136 nose samples were taken. Nasal sampling showed a higher prevalence of S. aureus among food handlers (29%) than hand sampling (9%). A high proportion of the strains (46%) were enterotoxigenic, and a considerable amount of food handlers carried enterotoxigenic S. aureus, 6% and 12% according to hand and nasal sampling, respectively. Pulsed-field gel electrophoresis macrorestriction profiles revealed a total of 32 different types as
APA, Harvard, Vancouver, ISO, and other styles
16

Gajewska, Joanna, Wioleta Chajęcka-Wierzchowska, and Anna Zadernowska. "Occurrence and Characteristics of Staphylococcus aureus Strains along the Production Chain of Raw Milk Cheeses in Poland." Molecules 27, no. 19 (2022): 6569. http://dx.doi.org/10.3390/molecules27196569.

Full text
Abstract:
Cheeses produced from unpasteurized milk by traditional production methods may contain many groups of microorganisms, including Staphylococcus aureus. The aim of this study was to determine the occurrence of S. aureus in the artisanal cheese production chain from unpasteurized milk. We investigated the prevalence of S. aureus strains isolated from various stages of artisanal cheese of unpasteurized milk production from farms in the northeastern and southern parts of Poland and characterized them. Characterization included antimicrobial susceptibility by microbroth dilution and biofilm formatio
APA, Harvard, Vancouver, ISO, and other styles
17

Asma, Omar Ali, and Najm Miftah. "The Provenance of Staphylococcus Aureus Isolated from Skin and Soft Tissue Infections and Its Antibiotic Susceptibility Patterns." Alq J Med App Sci 4, no. 2 (2021): 163–69. https://doi.org/10.5281/zenodo.5233949.

Full text
Abstract:
Objectives: The current study was aimed to evaluate the frequency and antibiotic susceptibility pattern of S. aureus isolated from various clinical specimens of patients admitted to Al Jala hospital during 2017 and 2018, and to figure out the prevalence of S. aureus strains among clinical specimens. Methods. A cross sectional study conducted in AL jala hospital during 2017-2018. About 226 clinical specimens were collected and inoculated in sheep blood agar, chocolate, and mannitol salt agar. Then incubated at 35 c for 18-24 hours in aerobic atomosphere. The Kirby-bauer disc diffusion method wa
APA, Harvard, Vancouver, ISO, and other styles
18

Bogdanovich, Tatiana, Duygu Esel, Linda M. Kelly, et al. "Antistaphylococcal Activity of DX-619, a New Des-F(6)-Quinolone, Compared to Those of Other Agents." Antimicrobial Agents and Chemotherapy 49, no. 8 (2005): 3325–33. http://dx.doi.org/10.1128/aac.49.8.3325-3333.2005.

Full text
Abstract:
ABSTRACT The in vitro activity of DX-619, a new des-F(6)-quinolone, was tested against staphylococci and compared to those of other antimicrobials. DX-619 had the lowest MIC ranges/MIC50s/MIC90s (μg/ml) against 131 Staphylococcus aureus strains (≤0.002 to 2.0/0.06/0.5) and 128 coagulase-negative staphylococci (0.004 to 0.25/0.016/0.125). Among strains tested, 76 S. aureus strains and 51 coagulase-negative staphylococci were resistant to ciprofloxacin. DX-619 had the lowest MIC50/MIC90 values against 127 quinolone-resistant staphylococci (0.125/0.5), followed by sitafloxacin (0.5/4), moxifloxac
APA, Harvard, Vancouver, ISO, and other styles
19

ChajÄ™cka-Wierzchowska, Wioleta, Anna Zadernowska, and Łucja Łaniewska-Trokenheim. "STAPHYLOCOCCUS AUREUS FROM READY-TO-EAT FOOD AS A SOURCE OF MULTIPLE ANTIBIOTIC RESISTANCE GENES." CBU International Conference Proceedings 5 (September 24, 2017): 1108–12. http://dx.doi.org/10.12955/cbup.v5.1079.

Full text
Abstract:
The emergence of antibiotic-resistant strains of S. aureus such as methicillin-resistant S. aureus (MRSA) is a worldwide problem. Ready-to-eat (RTE) food which does not need thermal processing before consumption could be a vehicle for the spread of antibiotic-resistant microorganisms. The present study evaluated the molecular genetic characteristics (RAPD) and pheno- and genotypical antimicrobial resistance profile of S. aureus isolated from 75 RTE food samples (sushi, hamburgers, salads). All of the isolates (n=32) were resistant to at least one class of antibiotic tested of which 75% strains
APA, Harvard, Vancouver, ISO, and other styles
20

Matsuo, Miki, Longzhu Cui, Jeeyoung Kim, and Keiichi Hiramatsu. "Comprehensive Identification of Mutations Responsible for Heterogeneous Vancomycin-Intermediate Staphylococcus aureus (hVISA)-to-VISA Conversion in Laboratory-Generated VISA Strains Derived from hVISA Clinical Strain Mu3." Antimicrobial Agents and Chemotherapy 57, no. 12 (2013): 5843–53. http://dx.doi.org/10.1128/aac.00425-13.

Full text
Abstract:
ABSTRACTHeterogeneous vancomycin-intermediateStaphylococcus aureus(hVISA) spontaneously produces VISA cells within its cell population at a frequency of 10−6or greater. We established a total of 45 VISA mutant strains independently obtained from hVISA Mu3 and its related strains by one-step vancomycin selection. We then performed high-throughput whole-genome sequencing of the 45 strains and their parent strains to identify the genes involved in the hVISA-to-VISA phenotypic conversion. A comparative genome study showed that all the VISA strains tested carried a unique set of mutations. All of t
APA, Harvard, Vancouver, ISO, and other styles
21

Pahadi, Prakash Chandra, Upendra Thapa Shrestha, Nabaraj Adhikari, Pradeep Kumar Shah, and Ritu Amatya. "Growing Resistance to Vancomycin among Methicillin Resistant Staphylococcus Aureus Isolates from Different Clinical Samples." Journal of Nepal Medical Association 52, no. 196 (2014): 977–81. http://dx.doi.org/10.31729/jnma.2797.

Full text
Abstract:
Introduction: Methicillin resistant Staphylococcus aureus (MRSA), majorly associated with nosocomial and community infections worldwide, are emerging as resistant strains to many antibiotics narrowing down the efficacy of antimicrobial therapy. In order to investigate the changing resistant pattern of MRSA to empirical drugs, the study was carried out at KIST Medical College and Hospital, Nepal. It also aims to determine the minimum inhibitory concentration of vancomycin among MRSA.
 Methods: Altogether 3500 clinical samples including 1303 blood, 1489 urine and 708 body fluids were collec
APA, Harvard, Vancouver, ISO, and other styles
22

Hu, Zhang, Hongrui Dong, Zhenyu Si, Yurong Zhao, and Yuanwei Liang. "Synthesis and Antibacterial Activity of Novel Triazolo[4,3-a]pyrazine Derivatives." Molecules 28, no. 23 (2023): 7876. http://dx.doi.org/10.3390/molecules28237876.

Full text
Abstract:
Infectious diseases pose a major challenge to human health, and there is an urgent need to develop new antimicrobial agents with excellent antibacterial activity. A series of novel triazolo[4,3-a]pyrazine derivatives were synthesized and their structures were characterized using various techniques, such as melting point, 1H and 13C nuclear magnetic resonance spectroscopy, mass spectrometry, and elemental analysis. All the synthesized compounds were evaluated for in vitro antibacterial activity using the microbroth dilution method. Among all the tested compounds, some showed moderate to good an
APA, Harvard, Vancouver, ISO, and other styles
23

Shopsin, B., M. Gomez, S. O. Montgomery, et al. "Evaluation of Protein A Gene Polymorphic Region DNA Sequencing for Typing of Staphylococcus aureus Strains." Journal of Clinical Microbiology 37, no. 11 (1999): 3556–63. http://dx.doi.org/10.1128/jcm.37.11.3556-3563.1999.

Full text
Abstract:
Three hundred and twenty isolates of Staphylococcus aureus were typed by DNA sequence analysis of the X region of the protein A gene (spa). spa typing was compared to both phenotypic and molecular techniques for the ability to differentiate and categorize S. aureus strains into groups that correlate with epidemiological information. Two previously characterized study populations were examined. A collection of 59 isolates (F. C. Tenover, R. Arbeit, G. Archer, J. Biddle, S. Byrne, R. Goering, G. Hancock, G. A. Hébert, B. Hill, R. Hollis, W. R. Jarvis, B. Kreiswirth, W. Eisner, J. Maslow, L. K.
APA, Harvard, Vancouver, ISO, and other styles
24

Cagnoli, Giulia, Fabrizio Bertelloni, Paolo Bongi, et al. "Nasal Carriage of Antimicrobial-Resistant Staphylococci by Fallow Deer (Dama dama) Taken in a Natural Park of Tuscany, Central Italy." Microorganisms 12, no. 11 (2024): 2323. http://dx.doi.org/10.3390/microorganisms12112323.

Full text
Abstract:
Wild animals are recognized as significant reservoirs for various zoonotic pathogens, including antibiotic-resistant bacteria. This study aimed to investigate the presence of Staphylococcus spp. strains in fallow deer (Dama dama) inhabiting a natural preserve in Central Italy and to examine the phenotypic and genotypic antimicrobial resistance and the presence of some virulence genes among the isolates. During July and December 2022, nasal swabs were collected from 175 fallow deer, which were then analyzed through bacteriological cultures. In total, 176 Staphylococcus spp. strains were isolate
APA, Harvard, Vancouver, ISO, and other styles
25

Huang, He, Yating Zhang, Qiu Du, Changji Zheng, Chenghua Jin, and Siqi Li. "Synthesis and Antimicrobial Activity of 3-Alkylidene-2-Indolone Derivatives." Molecules 29, no. 22 (2024): 5384. http://dx.doi.org/10.3390/molecules29225384.

Full text
Abstract:
The escalating threat of antibiotic-resistant bacteria and fungi underscores an urgent need for new antimicrobial agents. This study aimed to synthesize and evaluate the antimicrobial activities of two series of 3-alkylidene-2-indolone derivatives. We synthesized 32 target compounds, among which 25 exhibited moderate to high antibacterial or antifungal activities. Notably, compounds 10f, 10g, and 10h demonstrated the highest antibacterial activity with a minimum inhibitory concentration (MIC) of 0.5 μg/mL, matching the activity of the positive control gatifloxacin against three Gram-positive b
APA, Harvard, Vancouver, ISO, and other styles
26

Rana, Eaftekhar Ahmed, Tridip Das, Avijit Dutta, et al. "Coagulase-positive methicillin-resistant Staphylococcus aureus circulating in clinical mastitic goats in Bangladesh." July-2020 13, no. 7 (2020): 1303–10. http://dx.doi.org/10.14202/vetworld.2020.1303-1310.

Full text
Abstract:
Background and Aim: Staphylococcus aureus is argued as one of the principal organisms responsible for mammary gland infection in lactating goats, causing both clinical and subclinical mastitis. Being highly zoonotic potential, pathogen emergence of methicillin-resistant S. aureus (MRSA) has a significant clinical impact on treatment and management of clinical mastitis. We conducted a cross-sectional study to investigate the prevalence of coagulase-positive S. aureus (CoPS), antimicrobial resistance profile of Staphylococcus spp., prevalence of MRSA, and association between different clinical p
APA, Harvard, Vancouver, ISO, and other styles
27

Shah, SM Tanjil, Tanay Chakrovarty, Atiqua, et al. "Prevalence of Methicillin Resistant Staphylococcus aureus Carriage Amongst Healthcare Workers of Critical Care Units in Tertiary Hospitals of Jashore, Bangladesh." Bangladesh Journal of Microbiology 39, no. 2 (2023): 60–66. http://dx.doi.org/10.3329/bjm.v39i2.66266.

Full text
Abstract:
Staphylococcus aureus is responsible for numerous mild to severe diseases in humans in both hospital and community settings. This problem is getting even worse for multi-drug resistant S. aureus. Healthcare workers (HCWs) are in a threat of MRSA carriage and can serve as reservoirs. Therefore, this can lead to subsequent infection and cause a nosocomial outbreak of MRSA. This cross-sectional study involved 85 healthcare workers (HCWs) from surgery units and critical care units of five different tertiary hospitals at Jashore, Bangladesh. Nasal swab samples were collected and inoculated on selec
APA, Harvard, Vancouver, ISO, and other styles
28

Abalkhail, Adil, and Ayman Elbehiry. "Methicillin-Resistant Staphylococcus aureus in Diabetic Foot Infections: Protein Profiling, Virulence Determinants, and Antimicrobial Resistance." Applied Sciences 12, no. 21 (2022): 10803. http://dx.doi.org/10.3390/app122110803.

Full text
Abstract:
Staphylococcus aureus (S. aureus) is one of the most prevalent bacterial pathogens recovered from diabetic foot infections (DFIs). Most S. aureus isolates exhibit methicillin resistance, so treatment is recommended with antimicrobials active against methicillin-resistant S. aureus (MRSA) in patients who have risk factors associated with MRSA infections. The main goal of this study was to see if proteomics and molecular methods could be effective in identifying and distinguishing MRSA recovered from DFIs. Since MRSA is highly resistant to β-lactam antibiotics and usually does not respond to oth
APA, Harvard, Vancouver, ISO, and other styles
29

Rao, Muhammad Abid Khan, Ali Aamir, Parkash Om, Ahmed Qazi Muneer, and Nadeem Ali. "The emergence of vancomycin resistance among methicillin-resistant Staphylococcus aureus isolates from post-operative surgical site infections at District Jacobabad." Life Science Journal Of Pakistan 4, no. 1 (2022): 08–15. https://doi.org/10.5281/zenodo.6369323.

Full text
Abstract:
Surgical site infections (SSIs) are the most common post-operative infections and <em>Staphylococcus aureus</em> is the leading microbial cause. SSIs contribute significantly to morbidity and healthcare costs. The epidemiology and susceptibility pattern of <em>S. aureus</em> is fluctuating over time with the propagation of newer clones and the emergence of highly resistant strains. This cross-sectional study was conducted at Jacobabad Institute of Medical Sciences (JIMS) to determine the prevalence and antimicrobial susceptibility pattern of methicillin-resistant <em>Staphylococcus aureus </em
APA, Harvard, Vancouver, ISO, and other styles
30

Vestergaard, Martin, Sahar Roshanak, and Hanne Ingmer. "Targeting the ATP Synthase in Staphylococcus aureus Small Colony Variants, Streptococcus pyogenes and Pathogenic Fungi." Antibiotics 10, no. 4 (2021): 376. http://dx.doi.org/10.3390/antibiotics10040376.

Full text
Abstract:
The ATP synthase has been validated as a druggable target with the approval of the ATP synthase inhibitor, bedaquiline, for treatment of drug-resistant Mycobacterium tuberculosis, a bacterial species in which the ATP synthase is essential for viability. Gene inactivation studies have also shown that the ATP synthase is essential among Streptococci, and some studies even suggest that inhibition of the ATP synthase is a strategy for the elimination of Staphylococcus aureus small colony variants with deficiencies in the electron transport chain, as well as pathogenic fungi, such as Candida albica
APA, Harvard, Vancouver, ISO, and other styles
31

Chongtrakool, Piriyaporn, Teruyo Ito, Xiao Xue Ma, et al. "Staphylococcal Cassette Chromosome mec (SCCmec) Typing of Methicillin-Resistant Staphylococcus aureus Strains Isolated in 11 Asian Countries: a Proposal for a New Nomenclature for SCCmec Elements." Antimicrobial Agents and Chemotherapy 50, no. 3 (2006): 1001–12. http://dx.doi.org/10.1128/aac.50.3.1001-1012.2006.

Full text
Abstract:
ABSTRACT A description of staphylococcal cassette chromosome mec (SCCmec) elements carried by 615 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated in 11 Asian countries is reported, and a novel nomenclatural system based on their structures is proposed. The 615 strains were classified as type 3A (370 strains), type 2A (207 strains), type 2B (32 strains), type 1B (1 strain), and nontypeable (5 strains). The previously reported type III SCCmec (DDBJ/EMBL/GenBank accession no. AB037671) carried by the MRSA strain 85/2082 was ascertained to be composed of two SCC elements, type
APA, Harvard, Vancouver, ISO, and other styles
32

Chen, Feng-Jui, Chen-Her Wang, Ching-Yi Chen, Yu-Chieh Hsu, and Kaun-Ting Wang. "Role of themecAGene in Oxacillin Resistance in a Staphylococcus aureus Clinical Strain with apvl-Positive ST59 Genetic Background." Antimicrobial Agents and Chemotherapy 58, no. 2 (2013): 1047–54. http://dx.doi.org/10.1128/aac.02045-13.

Full text
Abstract:
ABSTRACTThe most prevalent community-associated methicillin-resistantStaphylococcus aureus(C-MRSA) strains in Taiwan, sequence type 59 (ST59) clones, carry staphylococcal cassette chromosomemec(SCCmec) type V and, to a lesser extent, type IV. These strains show wide variation in sensitivity to oxacillin, but the reasons for this variation are unknown. Here we compared the sequences of themecAgenes from clinical strains of different SCCmectypes and found that they contain differentmecApromoter mutations. Analysis ofmecApromoter activity by reporter gene fusions showed that single base substitut
APA, Harvard, Vancouver, ISO, and other styles
33

Bolatchiev, Albert. "Antibacterial activity of human defensins against Staphylococcus aureus and Escherichia coli." PeerJ 8 (November 25, 2020): e10455. http://dx.doi.org/10.7717/peerj.10455.

Full text
Abstract:
Background The global problem of antibiotic resistance requires the search for and development of new methods of treatment. One of the promising strategies is the use of low doses of antimicrobial peptides, in particular, human defensins HNP-1, hBD-1, and hBD-3, in combination with antibacterial drugs already used in clinical practice. This approach may be used to increase the effectiveness of conventional antibiotics. However, this requires thorough study of the effectiveness of defensins in combination with antibiotics against a large number of bacterial strains with known phenotypes of anti
APA, Harvard, Vancouver, ISO, and other styles
34

Buommino, Elisabetta, Adriana Vollaro, Francesca P. Nocera, et al. "Synergistic Effect of Abietic Acid with Oxacillin against Methicillin-Resistant Staphylococcus pseudintermedius." Antibiotics 10, no. 1 (2021): 80. http://dx.doi.org/10.3390/antibiotics10010080.

Full text
Abstract:
Resin acids are valued in traditional medicine for their antiseptic properties. Among these, abietic acid has been reported to be active against methicillin-resistant Staphylococcus aureus (MRSA) strains. In veterinary healthcare, the methicillin-resistant Staphylococcus pseudintermedius (MRSP) strain is an important reservoir of antibiotic resistance genes including mecA. The incidence of MRSP has been increasing, and treatment options in veterinary medicine are partial. Here, we investigated the antimicrobial and antibiofilm properties of abietic acid against three MRSP and two methicillin-s
APA, Harvard, Vancouver, ISO, and other styles
35

Darbani, Roya, Chiako Farshadfar, Somayeh Tavana, Hamidreza Saljoughi, and Sheida Sadat Zonouri. "Identification of DNA gyrase Subunit a Mutations Associated with Ciprofloxacin Resistance in Staphylococcus aureus Isolated from Nasal Infection in Kurdistan-Iran." Journal of Molecular Biology Research 7, no. 1 (2017): 186. http://dx.doi.org/10.5539/jmbr.v7n1p186.

Full text
Abstract:
Fluoroquinolone antibiotics such as ciprofloxacin are useful drugs against infections caused by Staphylococcus aureus and mutations in DNA gyrase which control bacterial DNA topology, can be one of the reason of occurrence resistance to this class of antibiotics. Therefore finding new mutations and study of the quinolone interaction with mutated GyrA can provide important issues for explanation resistance. In this study 5 ciprofloxacin resistance Staphylococcus aureus isolated among 50 collected S.aureus strains. By PCR testing, gyrA genes in resistance strains was amplified and nucleotide seq
APA, Harvard, Vancouver, ISO, and other styles
36

Okpala, Onyedika Emmanuel, Johana Rondevaldova, Hayford Osei-Owusu, Tomas Kudera, Tersia Kokoskova, and Ladislav Kokoska. "Susceptibility of Staphylococcus aureus to Anti-Inflammatory Drugs with a Focus on the Combinatory Effect of Celecoxib with Oxacillin In Vitro." Molecules 29, no. 15 (2024): 3665. http://dx.doi.org/10.3390/molecules29153665.

Full text
Abstract:
Musculoskeletal infections (MIs) are among the most difficult-to-treat staphylococcal diseases due to antibiotic resistance. This has encouraged the development of innovative strategies, such as combination therapy, to combat MI. The aim of this study was to investigate the in vitro antistaphylococcal activity of anti-inflammatory drugs and the combined antimicrobial effect of celecoxib and oxacillin. The minimum inhibitory concentrations (MICs) of 17 anti-inflammatory drugs against standard strains and clinical isolates of S. aureus, including methicillin-resistant strains (MRSAs), were deter
APA, Harvard, Vancouver, ISO, and other styles
37

Ngoi, Soo Tein, Anis Najwa Muhamad, Cindy Shuan Ju Teh та ін. "β-Lactam Resistance in Upper Respiratory Tract Pathogens Isolated from a Tertiary Hospital in Malaysia". Pathogens 10, № 12 (2021): 1602. http://dx.doi.org/10.3390/pathogens10121602.

Full text
Abstract:
The rise of antimicrobial resistance (AMR) among clinically important bacteria, including respiratory pathogens, is a growing concern for public health worldwide. Common causative bacteria for upper respiratory tract infections (URTIs) include Streptococcus pneumoniae and Haemophilus influenzae, and sometimes Staphylococcus aureus. We assessed the β-lactam resistant trends and mechanisms of 150 URTI strains isolated in a tertiary care hospital in Kuala Lumpur Malaysia. High rates of non-susceptibility to penicillin G (38%), amoxicillin-clavulanate (48%), imipenem (60%), and meropenem (56%) wer
APA, Harvard, Vancouver, ISO, and other styles
38

Prabhu, Kavitha, Sevitha Bhat, and Sunil Rao. "Bacteriologic Profile and Antibiogram of Blood Culture Isolates in a Pediatric Care Unit." Journal of Laboratory Physicians 2, no. 02 (2010): 085–88. http://dx.doi.org/10.4103/0974-2727.72156.

Full text
Abstract:
ABSTRACT Background / Aims: Septicemia is one of the important causes of mortality and morbidity in neonates and children. Blood culture is the gold standard for the diagnosis. Emergence of multidrug resistant bacterial strains is a major problem in the management of sepsis. Present study was undertaken to identify the common bacterial pathogens associated with pediatric sepsis and to determine their antibiotic susceptibility pattern. Materials and Methods: Blood cultures from 185 suspected cases of sepsis were examined. The growths from the subcultures were identified by conventional biochemi
APA, Harvard, Vancouver, ISO, and other styles
39

Nannini, Esteban C., Martin E. Stryjewski, Kavindra V. Singh, et al. "Inoculum Effect with Cefazolin among Clinical Isolates of Methicillin-Susceptible Staphylococcus aureus: Frequency and Possible Cause of Cefazolin Treatment Failure." Antimicrobial Agents and Chemotherapy 53, no. 8 (2009): 3437–41. http://dx.doi.org/10.1128/aac.00317-09.

Full text
Abstract:
ABSTRACT Methicillin (meticillin)-susceptible Staphylococcus aureus (MSSA) strains producing large amounts of type A β-lactamase (Bla) have been associated with cefazolin failures, but the frequency and impact of these strains have not been well studied. Here we examined 98 MSSA clinical isolates and found that 26% produced type A Bla, 15% type B, 46% type C, and none type D and that 13% lacked blaZ. The cefazolin MIC90 was 2 μg/ml for a standard inoculum and 32 μg/ml for a high inoculum, with 19% of isolates displaying a pronounced inoculum effect (MICs of ≥16 μg/ml with 107 CFU/ml) (9 type A
APA, Harvard, Vancouver, ISO, and other styles
40

Casanova, Valeska Paula, Juceam Appio, Eduardo Kohl, et al. "Bovine mastitis: prevalence and antimicrobial susceptibility profile and detection of genes associated with biofilm formation in Staphylococcus aureus." Semina: Ciências Agrárias 37, no. 3 (2016): 1369. http://dx.doi.org/10.5433/1679-0359.2016v37n3p1369.

Full text
Abstract:
Brazil currently ranks as one of the world leaders in food production and exportation. This scenario encourages the development of animal and plant health programs to ensure the production of safe food, helping the country to become an international provider of food for excellence. However, some health problems in dairy production, such as mastitis, have garnered increasing concern. This study aimed to estimate the prevalence of bovine mastitis in select properties located in the western Santa Catarina region, to assess the susceptibility profile to antimicrobial agents used for treatment and
APA, Harvard, Vancouver, ISO, and other styles
41

Qais, Faizan Abul, Anam Shafiq, Haris M. Khan, et al. "Antibacterial Effect of Silver Nanoparticles Synthesized Using Murraya koenigii (L.) against Multidrug-Resistant Pathogens." Bioinorganic Chemistry and Applications 2019 (July 1, 2019): 1–11. http://dx.doi.org/10.1155/2019/4649506.

Full text
Abstract:
Development of multidrug resistance among pathogens has become a global problem for chemotherapy of bacterial infections. Extended-spectrum β-lactamase- (ESβL-) producing enteric bacteria and methicillin-resistant Staphylococcus aureus (MRSA) are the two major groups of problematic MDR bacteria that have evolved rapidly in the recent past. In this study, the aqueous extract of Murraya koenigii leaves was used for synthesis of silver nanoparticles. The synthesized MK-AgNPs were characterized using UV-vis spectroscopy, FTIR, XRD, SEM, and TEM, and their antibacterial potential was evaluated on m
APA, Harvard, Vancouver, ISO, and other styles
42

Fenner, Lukas, Andreas F. Widmer, Marc Dangel, and Reno Frei. "Distribution of spa types among meticillin-resistant Staphylococcus aureus isolates during a 6 year period at a low-prevalence university hospital." Journal of Medical Microbiology 57, no. 5 (2008): 612–16. http://dx.doi.org/10.1099/jmm.0.47757-0.

Full text
Abstract:
This study describes the distribution and frequencies of strain types by protein A-encoding gene (spa) typing among a total of 200 meticillin-resistant Staphylococcus aureus (MRSA) single-patient isolates collected between 2000 and 2005 at the University Hospital Basel, Switzerland. Nine frequent spa types accounted for 49.5 % of MRSA isolates, whereas spa type t041 (15 % of all isolates) belonged to a local epidemic strain that is also a common strain type in southern Germany. Successful control of the outbreak strain was documented by epidemiological data and confirmed by spa typing results.
APA, Harvard, Vancouver, ISO, and other styles
43

Raza-e-Mustafa, Shaheen Iqbal Muhammad, Ansari Farheen, Sohail Muhammad, Rasool Karam, and Omer Muhammad. "Prevalence of mupirocin resistant (mupA) gene in S. aureus isolates from two tertiary care hospitals of Punjab." Pakistan Journal of Microbiology (PJM) 2, no. 1 (2021): 19–24. https://doi.org/10.5281/zenodo.5745327.

Full text
Abstract:
<strong>Introduction: </strong>Mupirocin is a topical ointment and de-colonizing agent, used to reduce the burden of <em>Staphylococcus aureus </em>from nasal nares. Unjudiciary use of mupirocin has resulted in the emergence of resistance mediated by a gene <em>mupA</em> found to be associated with high-level mupirocin (HLMup R) resistance. The objectives of this study were to find out the prevalence of MRSA/MSSA, <em>mupA</em> gene, and antimicrobial resistance among burn patients and outdoor patients. <strong>Material and Methods: </strong>A total of 238 non-repetitive specimens were collect
APA, Harvard, Vancouver, ISO, and other styles
44

D. Mbusi, Lucy, Silvester L. Lyantagaye, and Thomas Lyimo. "Characterization and bioprospecting of endophytic Actinomycetota from the leaves of the seagrasses Thalassia hemprichii and Syringodium isoetifolium." Western Indian Ocean Journal of Marine Science 24, no. 1 (2025): 87–101. https://doi.org/10.4314/wiojms.v24i1.9.

Full text
Abstract:
Bacteria of the phylum Actinomycetota are renowned for producing numerous bioactive compounds. Prior research has focused on terrestrial strains, rather than those from marine environments. This study aimed to isolate and characterize endophytic Actinomycetota bacterial strains from the leaves of the seagrasses Thalassia hemprichii and Syringodium isoetifolium from the coast of Tanzania, to analyze their bioactive metabolites against pathogenic micro-organisms. Fourteen isolates belonging to the genera Rhodococcus, Brachybacterium, Microbacterium, Kocuria, Gordonia, Janibacter, Flavobacterium,
APA, Harvard, Vancouver, ISO, and other styles
45

Akinduti, Akinniyi Paul, Joshua Adekunle Osiyemi, Temitope Temitayo Banjo, et al. "Clonal diversity and spatial dissemination of multi-antibiotics resistant Staphylococcus aureus pathotypes in Southwest Nigeria." PLOS ONE 16, no. 2 (2021): e0247013. http://dx.doi.org/10.1371/journal.pone.0247013.

Full text
Abstract:
Spread of genetically diverse Staphylococcus aureus characterized with multi-antibiotic resistance and regulated by high level agr functionalities in several communities in southwest Nigeria was investigated and evaluated for infection control. Staphylococcus aureus pathotypes recovered from 256 cases including purulent pus from skin infections, soft tissue aspirates, wounds, otorrhea, eye, throat and endocervical infections were assayed for biofilm and antibiogram. Further genotyped with micro-array, mapped for geospatial distribution and evaluated for clonal diversity and functional accessor
APA, Harvard, Vancouver, ISO, and other styles
46

Junnila, Jenna, Tiina Hirvioja, Esa Rintala, et al. "Changing epidemiology of methicillin-resistant Staphylococcus aureus in a low endemicity area—new challenges for MRSA control." European Journal of Clinical Microbiology & Infectious Diseases 39, no. 12 (2020): 2299–307. http://dx.doi.org/10.1007/s10096-020-03824-9.

Full text
Abstract:
AbstractThe incidence of methicillin-resistant Staphylococcus aureus (MRSA) has increased sharply in Hospital District of Southwest Finland (HD). To understand reasons behind this, a retrospective, population-based study covering 10 years was conducted. All new 983 MRSA cases in HD from January 2007 to December 2016 were analysed. Several data sources were used to gather background information on the cases. MRSA cases were classified as healthcare-associated (HA-MRSA), community-associated (CA-MRSA), and livestock contact was determined (livestock-associated MRSA, LA-MRSA). Spa typing was perf
APA, Harvard, Vancouver, ISO, and other styles
47

Dr., A. Geethanjali M.D FRSPH*1 Dr. R. Lakshmi Kumari M.D2 &. Dr. K. Rajasekhar M.D3. "AEROBIC BACTERIOLOGICAL STUDY IN SURGICAL SITE INFECTIONS WITH SPECIAL REFERENCE TO MRSA, VRSA & VRE." International Journal of Medical Research and Pharmaceutical Sciences 7, no. 7 (2020): 12–25. https://doi.org/10.5281/zenodo.3948894.

Full text
Abstract:
<strong>Context: </strong>Surgical Site Infections (SSI) has been responsible for the increasing cost, morbidity and mortality related to surgical operations. They continue to be a major problem even in hospitals with most modern facilities and standard protocols of preoperative preparation and antibiotic prophylaxis. <strong>Aim: </strong>The aim of this study to identify the aerobic bacteriological profile of Surgical Site Infections and its antibiogram, with special reference to Methicillin and Vancomycin resistance patterns of Staphylococcus aureus and Enterococci in this area. <strong>Set
APA, Harvard, Vancouver, ISO, and other styles
48

Sader, Helio S., David M. Johnson, and Ronald N. Jones. "In Vitro Activities of the Novel Cephalosporin LB 11058 against Multidrug-Resistant Staphylococci and Streptococci." Antimicrobial Agents and Chemotherapy 48, no. 1 (2004): 53–62. http://dx.doi.org/10.1128/aac.48.1.53-62.2004.

Full text
Abstract:
ABSTRACT LB 11058 is a novel parenteral cephalosporin with a C-3 pyrimidinyl-substituted vinyl sulfide group and a C-7 2-amino-5-chloro-1,3-thiazole group. This study evaluated the in vitro activity and spectrum of LB 11058 against 1,245 recent clinical isolates, including a subset of gram-positive strains with specific resistant phenotypes. LB 11058 was very active against Streptococcus pneumoniae. The novel cephalosporin was 8- to 16-fold more potent than ceftriaxone, cefepime, or amoxicillin-clavulanate against both penicillin-intermediate and -resistant S. pneumoniae. LB 11058 was also ver
APA, Harvard, Vancouver, ISO, and other styles
49

Zarrouk, Virginie, Bülent Bozdogan, Roland Leclercq, Louis Garry, Claude Carbon, and Bruno Fantin. "Influence of Resistance to Streptogramin A Type Antibiotics on the Activity of Quinupristin-Dalfopristin In Vitro and in Experimental Endocarditis Due toStaphylococcus aureus." Antimicrobial Agents and Chemotherapy 44, no. 5 (2000): 1168–73. http://dx.doi.org/10.1128/aac.44.5.1168-1173.2000.

Full text
Abstract:
ABSTRACT We evaluated the activity of quinupristin-dalfopristin (Q-D) against three clinical strains of Staphylococcus aureussusceptible to Q (MIC, 8 μg/ml) and Q-D (MICs, 0.5 to 1 μg/ml) but displaying various levels of susceptibility to D. D was active against S. aureus HM 1054 (MIC, 4 μg/ml) and had reduced activity against S. aureus RP 13 and S. aureus N 95 (MICs, 32 and 64 μg/ml, respectively). In vitro, Q-D at a concentration two times the MIC (2×MIC) produced reductions of 4.3, 3.9, and 5.8 log10 CFU/ml after 24 h of incubation for HM 1054, RP 13, and N 95, respectively. Comparable kill
APA, Harvard, Vancouver, ISO, and other styles
50

Mamtora, Dhruv, Sanjith Saseedharan, Ritika Rampal, et al. "In Vitro activity of a Novel Benzoquinolizine Antibiotic, Levonadifloxacin (WCK 771) against Blood Stream Gram-Positive Isolates from a Tertiary Care Hospital." Journal of Laboratory Physicians 12, no. 03 (2020): 230–32. http://dx.doi.org/10.1055/s-0040-1720944.

Full text
Abstract:
Abstract Background Blood stream infections (BSIs) due to Gram-positive pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) are associated with high mortality ranging from 10 to 60%. The current anti-MRSA agents have limitations with regards to safety and tolerability profile which limits their prolonged usage. Levonadifloxacin and its oral prodrug alalevonadifloxacin, a novel benzoquinolizine antibiotic, have recently been approved for acute bacterial skin and skin structure infections including diabetic foot infections and concurrent bacteremia in India. Methods The present
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography