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Journal articles on the topic 'Amoxicillin+potassium clavulanate'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Wald, Ellen R., Darleen Chiponis, and Jocyline Ledesma-Medina. "Comparative Effectiveness of Amoxicillin and Amoxicillin-Clavulanate Potassium in Acute Paranasal Sinus Infections in Children: A Double-Blind, Placebo-Controlled Trial." Pediatrics 77, no. 6 (1986): 795–800. http://dx.doi.org/10.1542/peds.77.6.795.

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This study compared the relative effectiveness of two antimicrobial preparations, amoxicillin and amoxicillin-clavulanate potassium (Augmentin), in the treatment of acute maxillary sinusitis in children 2 to 16 years of age. Of 171 children with persistent (ten to 30 days' duration) nasal discharge or daytime cough or both, 136 (80%) had abnormal maxillary sinus radiographs. These children were stratified by age and severity of symptoms and randomly assigned to receive either amoxicillin, amoxicillin-clavulanate potassium, or placebo. After the exclusion of 28 children with throat cultures pos

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Mann, Melinda S., Sebastian Faro, Maurizio L. Maccato, and Raymond H. Kaufman. "Treatment of Cervical Chlamydial Infection With Amoxicillin/Clavulanate Potassium." Infectious Diseases in Obstetrics and Gynecology 1, no. 2 (1993): 104–7. http://dx.doi.org/10.1155/s1064744993000249.

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Objective:To determine if amoxicillin/clavulanate potassium is effective in the treatment ofChlamydia trachomatisendocervicitis.Methods:Thirty-two patients with culture-proven endocervical infection were treated with amoxicillin/clavulanate potassium, 500 mg orally 3 times a day for 10 days. Post-treatment endocervical specimens were obtained at 2, 4, and 6 weeks for culture ofC. trachomatis. Male partners were treated with doxycycline, 100 mg orally twice daily for 10 days. The couples were provided condoms and asked to use them throughout the duration of the study.Results:All patients treate

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Reddy, K. Rajender, Patrick Brillant, and Eugene R. Schiff. "Amoxicillin-clavulanate potassium-associated cholestasis." Gastroenterology 96, no. 4 (1989): 1135–41. http://dx.doi.org/10.1016/0016-5085(89)91633-8.

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Wang, Guilian. "Comparison of Efficacy of Amoxicillin/Clavulanate Potassium and Azithromycin Sequential Therapies on Nutritional Status of Children with Bronchopneumonia." Current Topics in Nutraceutical Research 22, no. 2 (2024): 466–72. http://dx.doi.org/10.37290/ctnr2641-452x.22:466-472.

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Bronchopneumonia is a highly prevalent respiratory disease among malnourished children and infants, and it is mainly treated with antibiotics. Herein, we compared the efficacy of amoxicillin/clavulanate potassium and azithromycin sequential therapies for bronchopneumonia. We found that amoxicillin/clavulanate potassium had improved clinical efficacy and accelerated rehabilitation in patients with bronchopneumonia. Azithromycin demonstrated superior efficacy in inhibiting inflammation, enhancing nutritional status, and regulating trace element levels. The therapeutic safety profile of the two s

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Nugrahani, I., S. N. Soewandhi, S. Ibrahim, and S. Asyarie. "Amoxicillin trihydrate–potassium clavulanate solid solution." Acta Crystallographica Section A Foundations of Crystallography 64, a1 (2008): C436. http://dx.doi.org/10.1107/s0108767308086005.

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Devi, Anjana, Sanjay Kumar, Kamal Jeet, Vikash Sharma, and Aman Chaudhary. "Review on process validation of Amoxicillin Potassium Clavulanate Dry Syrup." Asian Journal of Pharmaceutical Research and Development 10, no. 4 (2022): 102–7. http://dx.doi.org/10.22270/ajprd.v10i4.1146.

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Modern medicines for human use are required to comply with specific standards and regulation set forth by the concerned authorities. A simple and sensitive UV spectrophotometric method was developed and validated for the simultaneous determination of Potassium Clavulanate (PC) and Amoxicillin. As complementary of this work, an assay method for amoxicillin and potassium clavulanate mixtures was developed and validated; stress-testing and stability studies of amox/clav mixtures was carried out under specified conditions according to ICH and analyzed by using validated stability-indicating assay

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Manuel, Ruíz-Piñón, Gancedo-Gancedo Tania, Seoane-Prado Rafael, et al. "In Vitro Development of a New Sponge-Based Delivery System for Intracanal Antimicrobial Administration in Endodontic Treatment." Journal of Clinical Medicine 10, no. 12 (2021): 2725. http://dx.doi.org/10.3390/jcm10122725.

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This study aimed to evaluate the in vitro performance of collagen-based sponges as a drug delivery system for intracanal antimicrobial administration. Four groups of loaded collagen-based sponges (A, 0.3% w/v amoxicillin trihydrate: potassium clavulanate (4:1); B, 0.03% w/v chlorhexidine gluconate [CHX]; C, 0.3% w/v amoxicillin trihydrate: potassium clavulanate (4:1) and 0.03% w/v CHX; D, 1% w/v amoxicillin trihydrate: potassium clavulanate (4:1) and 0.03% w/v CHX) were designed. Release kinetics were tested in vitro on cultures in Petri dishes, and the effect on bacterial biofilms was studied

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Sydnor, Thomas Austin, William Michael Scheld, Jack Gwaltney, Richard W. Nielsen, Werner Huck, and Donal G. Therasse. "Loracarbef (LY163892) vs Amoxicillin/Clavulanate in Bacterial Maxillary Sinusitis." Ear, Nose & Throat Journal 71, no. 5 (1992): 225–32. http://dx.doi.org/10.1177/014556139207100505.

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Loracarbef (LY 163892), a β-lactam antibiotic (carbacephem), was compared with amoxicillin/ clavulanate potassium in a 10-day, single-blind, randomized parallel trial in the treatment of acute bacterial maxillary sinusitis. Based on posttherapy aspirate and culture, there was a 95.2% bacteriologic cure rate in patients receiving loracarbef (400 mg twice daily) and an 86.7% cure rate in patients receiving amoxicillin/clavulanate (500/125 mg three times daily) ( p = 0.359). Loracarbef was comparable in efficacy to amoxicillin/clavulanate with a more desirable safety profile.

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9

Jerzsele, Ákos, and Gábor Nagy. "The stability of amoxicillin trihydrate and potassium clavulanate combination in aqueous solutions." Acta Veterinaria Hungarica 57, no. 4 (2009): 485–93. http://dx.doi.org/10.1556/avet.57.2009.4.3.

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The effect of various environmental factors on the stability of aqueous solutions of amoxicillin-clavulanic acid combination in a veterinary water-soluble powder product was investigated. In the swine industry, the combination is administered via the drinking water, where both substances are quickly decomposed depending on several environmental factors. The degradation rate of the substances was determined in solutions of different water hardness levels (German hardness of 2, 6 and 10) and pH values (3.0, 7.0 and 10.0), and in troughs made of different materials (metal or plastic). Increasing

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Balvant Lunge, Snehal, Vijaya V. Sajjan, Ashok M. Pandit, B. S. Manjunathswamy, Shivakumar Patil, and Anshul Agrawal. "Amoxicillin and clavulanate potassium related Leucocytoclastic vasculitis." Our Dermatology Online 5, no. 2 (2014): 148–50. http://dx.doi.org/10.7241/ourd.20142.35.

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Zhu, Xiaoli, Zongcheng Wei, and Xia Liu. "Efficacy of Ambroxol Hydrochloride Combined with Amoxicillin Potassium Clavulanate Combination on Children with Bronchopneumonia and Its Impact on the Level of Inflammatory Factors." Evidence-Based Complementary and Alternative Medicine 2022 (August 19, 2022): 1–5. http://dx.doi.org/10.1155/2022/2604114.

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Objective. The goal of the present study was to examine the effect of ambroxol hydrochloride combined with amoxicillin potassium clavulanate combination on children with bronchopneumonia and its influence on the level of inflammatory factors. Methods. From January 2018 to June 2019, 100 children with bronchopneumonia admitted to the Pediatric Department of Nanjing Pukou District Hospital of Traditional Chinese Medicine were enrolled as the study subjects. The children were assigned either to an observation group or a control group in a ratio of 1:1 using the random alphabet method. The observa

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McLeod, Donald C., Bruce R. Smith та Jack L. LeFrock. "Amoxicillin-Potassium Clavulanate: A Novel β-Lactamase Inhibitor". Drug Intelligence & Clinical Pharmacy 19, № 6 (1985): 415–20. http://dx.doi.org/10.1177/106002808501900601.

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13

Zhang, Shengjun, Zhenghua Wang, and Guoping Xu. "Effect of Amoxicillin and Clavulanate Potassium Combined with Bazhengsan on Pediatric Urinary Tract Infection." Evidence-Based Complementary and Alternative Medicine 2021 (October 20, 2021): 1–7. http://dx.doi.org/10.1155/2021/4575503.

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Objective. To explore the therapeutic effect of amoxicillin and clavulanate potassium combined with Bazhengsan on pediatric urinary tract infection (UTI). Methods. The data of 120 UTI children treated in Wuhan Xinzhou District People’s Hospital from February 2019 to February 2020 were retrospectively analyzed. They were equally split into experimental group (EG) and control group (CG) according to the order of admission. All children were treated with amoxicillin and clavulanate potassium for suspension (twice a day), and EG was additionally treated with one dose of Bazhengsan daily. Both grou

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Smith, Gillian M., Brian Slocombe, Karen H. Abbott, and Linda W. Mizen. "Activity of Amoxicillin-Clavulanate against Penicillin-Resistant Streptococcus pneumoniae in an Experimental Respiratory Infection Model in Rats." Antimicrobial Agents and Chemotherapy 42, no. 4 (1998): 813–17. http://dx.doi.org/10.1128/aac.42.4.813.

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ABSTRACT High doses of amoxicillin, equivalent to those produced by 500- and 750-mg oral doses in humans (area under the plasma concentration-time curve), were effective against a penicillin-resistant strain ofStreptococcus pneumoniae in an experimental respiratory tract infection in immunocompromised rats; this superior activity confirms the results of previous studies. An unexpected enhancement of amoxicillin’s antibacterial activity in vivo against penicillin-resistant and -susceptible S. pneumoniaestrains was observed when subtherapeutic doses of amoxicillin were coadministered with the β-

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S. Shaokat, Siham, and Hamoudi A. Hameed. "Synergistic Effect of Potassium Clavulanate in Combination withCefamandol and Ceftazidime on B- Lactamase, Extracted From Resistant E.coli." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 15, no. 2 (2017): 8–16. http://dx.doi.org/10.31351/vol15iss2pp8-16.

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The aim of this study was to evaluate in-vitro activity of Cefamandol and Ceftazidime, in combination with potassium clavulanate against 10 uropathogenic E.coli isolated from patients with chronic complicated urinary tract infections (UTIs), these isolates were identified by the Api identification systems.The antimicrobial susceptibility tests were determined by Kirby-Bauer method and the minimum inhibitory concentrations of Cefamandol and Ceftazidime, were determined, by tube method. These isolates were resistant to Ampicillin (Amp), Amoxicillin (Amo), Carbenicillin (Cb), Ticarcillin (Tic), A

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Davydov, Liya, Marina Yermolnik, and Lewis J. Cuni. "Warfarin and Amoxicillin/Clavulanate Drug Interaction." Annals of Pharmacotherapy 37, no. 3 (2003): 367–70. http://dx.doi.org/10.1345/aph.1c243.

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OBJECTIVE: To report a case of warfarin–amoxicillin/clavulanate potassium (AM/CL) interaction resulting in an elevated international normalized ratio (INR) and hematuria. CASE SUMMARY: A 58-year-old Hawaiian/Asian/European woman developed an elevated INR and microscopic hematuria as a result of a drug–drug interaction between warfarin and AM/CL. DISCUSSION: Our report of an increased INR with bleeding complications as a result of an interaction between warfarin and AM/CL is consistent with those in the literature. Although the mechanism for this interaction is not fully known, it is suspected

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Jiang, Rong-San, Jinq-Wen Jang, and Chen-Yi Hsu. "Bacteriology of Chronic Sinusitis after Amoxicillin-Clavulanate Potassium Therapy." Otolaryngology–Head and Neck Surgery 124, no. 6 (2001): 683–86. http://dx.doi.org/10.1177/019459980112400616.

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Jiang, R. "Bacteriology of chronic sinusitis after amoxicillin-clavulanate potassium therapy." Otolaryngology - Head and Neck Surgery 124, no. 6 (2001): 683–86. http://dx.doi.org/10.1067/mhn.2001.115059.

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19

V.Vijaya, Prasad* P.Venkata Sravan Kumar Dr R. Siddarama. "DEATH DUE TO STEVENS JOHNSON SYNDROME; A RARE CASE REPORT." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2072–76. https://doi.org/10.5281/zenodo.835176.

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Stevens Johnson’s syndrome is a life threatening drug induced hypersensitivity reaction. The drugs that cause SJS commonly are antibacterials (sulfonamides), anticonvulsants (phenytoin, phenobarbital, and carbamazepine), non-steroidal anti-inflammatory drugs (oxicam derivatives) and oxide inhibitors (allopurinol).Clinical symptoms are urticarial skin eruptions, arthralgia or arthritis, lymphadenopathy and fever.Treatment of Stevens Johnsons Syndrome includes systemic steroids, cyclosporine, intravenous immunoglobulin’s and supportive therapy.A male patient of 58 years was admitted in cardiolog

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20

Zhang, Li-li, Li-li Wang, Mei You, et al. "Effect of amoxicillin-clavulanate potassium and potential factors influencing umbilical cord separation time in preterm infants." Tropical Journal of Pharmaceutical Research 23, no. 7 (2024): 1189–98. http://dx.doi.org/10.4314/tjpr.v23i7.18.

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Purpose: To investigate the effect of amoxicillin-clavulanate potassium and potential factors influencing umbilical cord separation time in preterm infants. Methods: A total of 151 preterm infants admitted to the Neonatology Department, First Affiliated Hospital of Anhui Medical University, Hefei, China, from November 2020 to June 2021 were selected. Preterm infants were randomly divided into control and study groups. Control group received 2 % povidone-iodine and 75 % ethanol application, followed by gentle pressure with a cotton swab while the study group received amoxicillin-clavulanate pot

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21

Hoban, Daryl J., and Jos Nauta. "Clarithromycin versus Amoxicillin alone or with Clavulanate in Acute Maxillary Sinusitis: A Meta-analysis of Clinical Trials." Open Infectious Diseases Journal 13, no. 1 (2021): 1–9. http://dx.doi.org/10.2174/1874279302113010001.

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Objective: A meta-analysis was performed to explore the relative effects of clarithromycin and amoxicillin (with or without clavulanate potassium) in the treatment of acute maxillary sinusitis. Methods: Six studies were identified in the peer-reviewed literature. All were randomized single-blind (investigator-blind) or open-label trials in outpatients diagnosed with acute maxillary sinusitis. A total of 1580 patients were enrolled, of whom 1194 were clinically evaluable. The total daily dose of clarithromycin was 1000 mg; the total daily dose of amoxicillin (with or without clavulanate potassi

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Javed, Sumreen. "TREATMENT OF UPPER RESPIRATORY TRACT INFECTION: A CASE REPORT." Canadian Journal of Applied Sciences 2 (2012): 1. http://dx.doi.org/10.21065/19257430.2.1.

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Respiratory tract infections are the most common infections in the developing countries. Its mode of spread is also very fast as compared to any other infection. Therefore; we have aimed this study based on the administration of two different drugs, Ciprox (Ciprofloxacin) and Augmentin (amoxicillin/clavulanate potassium), for the treatment of upper respiratory tract infection.

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Kutcherenko, M. A., A. M. Savitcheva, Z. M. Martikainen, and S. L. Zaciorskaya. "The efficiency of Amoxicillin/ Potassium Clavunalatis application in complicated postlabor period." Journal of obstetrics and women's diseases 48, no. 4 (1999): 39–41. http://dx.doi.org/10.17816/jowd89011.

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The investigation has shown that step therapy with Amoxicillin/Clavulanate (1,2 gr. IV bid 3 days) with further transfer to peroral administration of the drug in dosage of 625 mg tid 4 days) ensures a high clinical and bacteriological effectiveness in maternity with complicated postlabor period. The identical results are received with compared randomized trial with the use of ampicillin +gentamycin+metronidazole.

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Yu, Zugong, Feng Wu, Jing Tian, Xuewen Guo, Ran An, and Yangyang Guo. "Ammonium glycyrrhizin counteracts liver injury caused by lipopolysaccharide/amoxicillin-clavulanate potassium." Oncotarget 8, no. 57 (2017): 96837–51. http://dx.doi.org/10.18632/oncotarget.18291.

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LIU, XiangFang, Yang SHEN, and HuaJun SUN. "Discussion on the package insert expression for amoxicillin sodium/potassium clavulanate." Pharmaceutical Care and Research 14, no. 1 (2014): 54–62. http://dx.doi.org/10.5428/pcar20140118.

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Vilà-Nadal, G., R. Lleonart Bellfill, J. Martí Garrido, C. Baliellas Comellas, and M. Corominas Sánchez. "Recurrent Drug-Induced Liver Injury With Cetirizine and Amoxicillin–Clavulanate Potassium." Journal of Investigational Allergology and Clinical Immunology 29, no. 4 (2019): 321–22. http://dx.doi.org/10.18176/jiaci.0397.

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Souza, A., B. B. Moreno, J. E. Almeida, S. O. Rogero, C. D. S. Pereira, and J. R. Rogero. "Cytotoxicity evaluation of Amoxicillin and Potassium Clavulanate in Perna perna musselss." Ecotoxicology and Environmental Contamination 11, no. 1 (2016): 21–26. http://dx.doi.org/10.5132/eec.2016.01.04.

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Jacobs, Michael, and Jack B. Anon. "Amoxicillin/potassium clavulanate is effective treatment for acute bacterial sinusitis in children." Journal of Pediatrics 156, no. 1 (2010): 166. http://dx.doi.org/10.1016/j.jpeds.2009.09.061.

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Andjelic, Sladjana, Slobodan Savic, and Dusko Kozic. "Amoxicillin-clavulanate prescribed in a patient with known penicillin allergy." Srpski arhiv za celokupno lekarstvo 148, no. 7-8 (2020): 493–96. http://dx.doi.org/10.2298/sarh191222024a.

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Introduction. Prescription of penicillin requires extra caution in order to avoid its administration in a person allergic to this antibiotic. We present a case of a patient allergic to penicillin, to whom a doctor prescribed this medicine by mistake. Case outline. An 18-year-old female patient turned to an otolaryngologist because of a sore throat, difficulty in breathing, and light clogging in the left ear during several previous days. The patient tolerated oral intake of only liquid foods. She reported frequent attacks of tonsillopharyngitis, and an allergy to penicillin. Tonsillopharyngitis

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Guoxin, Hu, Dai Zongshun, Long Lihong, Han Ying, Hou Shuxian, and Wu Li. "Bioequiwalence of clavulanate Potassium and Amoxicillin (1∶7) dispersible tablets in healthy volunteers." Journal of Huazhong University of Science and Technology [Medical Sciences] 22, no. 3 (2002): 224–27. http://dx.doi.org/10.1007/bf02828186.

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M, Yelibora, Obiri-Yeboah S, Larmie R.N.L, Olesu J.T, Oti Acheampong A, and Donkor P. "A retrospective study of ludwig’s angina at the maxillofacial unit of the komfo anokye teaching hospital-kumasi, Ghana." Ghana Dental Journal 20, no. 1 (2023): 26–29. http://dx.doi.org/10.4314/gdj.v20i1.5.

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Introduction: Ludwig’s angina is a potentially life-threatening diffuse cellulitis involving the sublingual, submental, and submandibular spaces bilaterally and causing progressive airway obstruction. The microbiology of Ludwig’s angina is polymicrobial, but commonly isolated is Streptococcal spp. Aim: The current study aimed to retrospectively evaluate the prevalence of Ludwig’s angina at the Maxillofacial Unit of the Komfo Anokye Teaching Hospital, Ghana. Materials & Methods: A 2-year retrospective analysis of patient records from January 2012 to December 2013 was undertaken. The studied

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Tu, Yu-Hsing, Mary L. Stiles, Loyd V. Allen, Keith M. Olsen, Charles I. Barton, and Robert B. Greenwood. "Stability of Amoxicillin Trihydrate-Potassium Clavulanate in Original Containers and Unit Dose Oral Syringes." American Journal of Health-System Pharmacy 45, no. 5 (1988): 1092–99. http://dx.doi.org/10.1093/ajhp/45.5.1092.

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KALEIDA, PHILLIP H., CHARLES D. BLUESTONE, HOWARD E. ROCKETTE, et al. "Amoxicillin-clavulanate potassium compared with cefaclor for acute otitis media in infants and children." Pediatric Infectious Disease Journal 6, no. 3 (1987): 265–71. http://dx.doi.org/10.1097/00006454-198703000-00013.

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Bejjani, A., M. Roumié, S. Akkad, F. El-Yazbi, and B. Nsouli. "Simultaneous quantification of amoxicillin and potassium clavulanate in different commercial drugs using PIXE technique." Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 371 (March 2016): 392–95. http://dx.doi.org/10.1016/j.nimb.2015.10.055.

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Wald, E. R., D. Nash, and J. Eickhoff. "Effectiveness of Amoxicillin/Clavulanate Potassium in the Treatment of Acute Bacterial Sinusitis in Children." PEDIATRICS 124, no. 1 (2009): 9–15. http://dx.doi.org/10.1542/peds.2008-2902.

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Stockman, J. A. "Effectiveness of Amoxicillin/Clavulanate Potassium in the Treatment of Acute Bacterial Sinusitis in Children." Yearbook of Pediatrics 2011 (January 2011): 94–96. http://dx.doi.org/10.1016/s0084-3954(09)79599-5.

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Martinazzi, Brandon J., Gregory Kirchner, Hannah Nam, et al. "Prophylaxis for the Prevention of PJI after TAA: Is It Economically Justifiable?" Foot & Ankle Orthopaedics 7, no. 4 (2022): 2473011421S0078. http://dx.doi.org/10.1177/2473011421s00783.

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Category: Ankle Arthritis; Ankle; Other Introduction/Purpose: Prosthetic joint infection (PJI) is a costly and potentially fatal complication in total ankle arthroplasty (TAA). Some surgeons will use intraoperative vancomycin powder or copiously irrigate the surgical site with Povidone-iodine to prevent this outcome. Additionally, many surgeons will prescribe a short course of postoperative antibiotics. However, the efficacy of such prophylaxis continues to be debated, and little is known about the cost-effectiveness of these agents. Therefore, the purpose of this study was to perform a 'break

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S. Shaokat, Siham, and Hamoudi A. Hameed. "Evaluation of Stability of Cefamandol and Ceftazidime with Clavulanic Acid Against Extended Spectrum ?- Lactamase." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 19, no. 2 (2017): 42–47. http://dx.doi.org/10.31351/vol19iss2pp42-47.

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The aim of this study is to evaluate in-vitro activity of Cefamandol (Cfm) and Ceftazidime (Cfz), in combination with Clavulanic acid (CA) against ten complicated multiresistant uropathogenic E.coli .One hundred clinical strains were isolated from patients with chronic urinary tract infections (UTIs), these isolates were identified by the Api identification systems. The antimicrobial susceptibility tests were determined by Kirby-Bauer method, all of them were sensitive to Imipenem (Imp). Ten strains were chosen for the present study, they were resistant to Ampicillin (Amp), Amoxicillin (Amo),

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Sclafani, Anthony P., Jeffrey Ginsburg, Mahendra K. Shah, and Jay N. Dolitsky. "Treatment of Symptomatic Chronic Adenotonsillar Hypertrophy With Amoxicillin/Clavulanate Potassium: Short- and Long-term Results." Pediatrics 101, no. 4 (1998): 675–81. http://dx.doi.org/10.1542/peds.101.4.675.

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Abdulameer, Sarah S., and Khaleda H. Al-Saidi. "Simultaneous determination of amoxicillin and potassium clavulanate antibiotics in pharmacueutical sample using derivative spectrophotometric method." Journal of Biotechnology Research Center 5, no. 3 (2011): 49–60. http://dx.doi.org/10.24126/jobrc.2011.5.3.184.

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Derivatives spectrophotometric techniques were developed for the determination of Amoxicillin Trihydrate (Amox) with Potassium Clavulanate (PC) antibiotic binary mixtures. The simultaneous determination of these compounds was accomplished by derivative (1D, 2D and 3D) spectrophotometric technique and applying zero-crossing technique used for determination of (Amox) and (PC) in tablets. The second order derivative absorption spectra at valley λ=299 nm were used for (Amox) and also the second order derivative spectra at peak λ=239.5 nm were used for (PC). No interferences were found between both

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Bakken, J. S., J. N. Bruun, P. Gaustad, and T. C. Tasker. "Penetration of amoxicillin and potassium clavulanate into the cerebrospinal fluid of patients with inflamed meninges." Antimicrobial Agents and Chemotherapy 30, no. 3 (1986): 481–84. http://dx.doi.org/10.1128/aac.30.3.481.

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Marra, Mariana C., Rafael R. Cunha, Rodrigo A. A. Muñoz, Alex D. Batista, and Eduardo M. Richter. "Single-run capillary electrophoresis method for the fast simultaneous determination of amoxicillin, clavulanate, and potassium." Journal of Separation Science 40, no. 17 (2017): 3557–62. http://dx.doi.org/10.1002/jssc.201700478.

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Wei, Kai, Qianqian Wang, Geer Teng, Xiangjun Xu, Zhifang Zhao, and Guoyan Chen. "Application of Laser-Induced Breakdown Spectroscopy Combined with Chemometrics for Identification of Penicillin Manufacturers." Applied Sciences 12, no. 10 (2022): 4981. http://dx.doi.org/10.3390/app12104981.

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Due to the differences in raw materials and production processes, the quality of the same type of drug produced by different manufacturers is different. In drug supervision, determining the manufacturer can help to trace drug quality issues. In this study, a method for the quick identification of drug manufacturers based on laser-induced breakdown spectroscopy (LIBS) was proposed for the first time. We obtained the LIBS spectra from 12 samples of three types of penicillin (phenoxymethylpenicillin potassium tablets, amoxicillin capsules, and amoxicillin and clavulanate potassium tablets) produc

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Grandis, Jennifer R., Jonas T. Johnson, Richard M. Vickers, et al. "The Efficacy of Perioperative Antibiotic Therapy on Recovery following Tonsillectomy in Adults: Randomized Double-Blind Placebo-Controlled Trial." Otolaryngology–Head and Neck Surgery 106, no. 2 (1992): 137–42. http://dx.doi.org/10.1177/019459989210600203.

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One hundred and one adult patients undergoing tonsillectomy for chronic/recurrent tonsillitis completed a prospective, randomized, double-blind, placebo-controlled study in which ticarcillin disodium and clavulanate potassium (Timentin) or placebo was administered intravenously at the time of surgery and for 12 hours postoperatively. The patients than received oral amoxicillin and clavulanate potassium (Augmentin) therapy or placebo for an additional seven days. Each patient kept a daily log to assess the incidence and severity of postoperative symptoms. Tonsillar core tissue at the time of su

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Wang, Yan, Fengzhu Xie, Fang Chen, Wenting Su, and Yiqun Zhou. "Effect of cefazolin sodium and amoxicillin sodium/clavulanate potassium on postoperative infection, pain and expression of inflammatory factors in patients undergoing orthopedic surgery." Tropical Journal of Pharmaceutical Research 22, no. 11 (2024): 2365–71. http://dx.doi.org/10.4314/tjpr.v22i11.17.

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Purpose: To investigate the comparative effect of two antibacterial treatments in orthopedic surgery. Methods: A total of 96 patients who had undergone orthopedic surgery in Department of Nosocomial Infection Management, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Suzhou, China from January 2021 to December 2022 were retrospectively analyzed and equally divided into two groups based on the postoperative medications administered to prevent infection. The control group was treated with amoxicillin sodium/clavulanate potassium while the study group was treated wi

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Epstein, Shelley, and Robert Hardy. "Clinical Resolution of Nasal Aspergillosis Following Therapy with a Homeopathic Remedy in a Dog." Journal of the American Animal Hospital Association 47, no. 6 (2011): e110-e115. http://dx.doi.org/10.5326/jaaha-ms-5560.

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A 6 yr old, male, neutered Weimaraner was treated homeopathically for nasal aspergillosis after failing to respond to two treatments of topical (intranasal) clotrimazole and oral amoxicillin trihydrate/clavulanate potassium. Computed tomography, rhinoscopy, fungal culture, and cytology previously confirmed the diagnosis. At presentation for homeopathic treatment, the dog had aggressive left-sided sinusitis and rhinitis with destruction of nasal turbinates and severe bouts of epistaxis. Erosion and depigmentation of the nasal planum were evident. After two treatments with homeopathic aurum meta

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Chomel, Bruno B., Jane A. Morton, Rickie W. Kasten, and Chao-chin Chang. "First Pediatric Case of Tularemia after a Coyote Bite." Case Reports in Infectious Diseases 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/8095138.

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Bite-transmitted tularemia is a rare event in humans and most of the cases have been associated with cat bites. We report the first pediatric case of tularemia caused by a coyote (Canis latrans) bite. Coyotes can be healthy carriers ofFrancisella tularensisand transmit this infectious agent through a bite. Pediatricians should be aware of this risk after a carnivore bite and implement appropriate antibiotic therapy, as amoxicillin/clavulanate potassium (Augmentin) may have prolonged the typical two to three days’ incubation period commonly observed for tularemia after an animal bite and was no

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Ashfaq, Anum. "Moxifloxacin Causing Lazy Heart: A Case Report." Journal of Clinical Case Reports and Studies 6, no. 4 (2025): 01–02. https://doi.org/10.31579/2690-8808/257.

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Bradycardia is defined as heart rate less than 60bpm in adults (Normal heart rate is 60-100bpm in adults). There are many causes of bradycardia including medications which can cause mild to severe depression in heart rate even leading to cardiac arrest and death. Here is the case of an elderly man with no pre-morbid condition who took moxifloxacin for the treatment of acute rhinosinusitis. He developed dizziness and generalized fatigue on second day of antibiotic treatment. His complete blood picture, liver function tests, renal function tests, serum electrolytes including magnesium and potass

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Kleinfelder, J. W., R. F. Müller, and D. E. Lange. "Bacterial susceptibility to amoxicillin and potassium clavulanate in advanced periodontitis patients not responding to mechanical therapy." Journal of Clinical Periodontology 27, no. 11 (2000): 846–53. http://dx.doi.org/10.1034/j.1600-051x.2000.027011846.x.

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Dobrova, Anna O., Olga S. Golovchenko, Ivan V. Bezruk, Liudas Ivanauskas, and Victoriya Georgiyants. "Simultaneous determination of amoxicillin and potassium clavulanate in combined medicinal forms: procedure transfer from HPLC to UPLC." Česká a slovenská farmacie 69, no. 4 (2020): 186–93. https://doi.org/10.36290/csf.2020.026.

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