Journal articles on the topic 'AMPAkine'
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Wollman, L. B., K. A. Streeter, and D. D. Fuller. "Ampakine pretreatment enables a single brief hypoxic episode to evoke phrenic motor facilitation." Journal of Neurophysiology 123, no. 3 (2020): 993–1003. http://dx.doi.org/10.1152/jn.00708.2019.
Full textTurner, S. M., M. K. ElMallah, A. K. Hoyt, J. J. Greer, and D. D. Fuller. "Ampakine CX717 potentiates intermittent hypoxia-induced hypoglossal long-term facilitation." Journal of Neurophysiology 116, no. 3 (2016): 1232–38. http://dx.doi.org/10.1152/jn.00210.2016.
Full textSu, Chen, Hau Yeuh Lin, Runtao Yang, et al. "AMPAkines Target the Nucleus Accumbens to Relieve Postoperative Pain." Anesthesiology 125, no. 5 (2016): 1030–43. http://dx.doi.org/10.1097/aln.0000000000001336.
Full textRen, Jun, Xiuqing Ding, and John J. Greer. "Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717." Journal of Applied Physiology 113, no. 7 (2012): 1004–11. http://dx.doi.org/10.1152/japplphysiol.00752.2012.
Full textHachem, LD, AJ Mothe, and CH Tator. "P.089 AMPA receptor modulation as a therapeutic strategy to enhance survival of spinal cord neural stem cells." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 45, s2 (2018): S39—S40. http://dx.doi.org/10.1017/cjn.2018.191.
Full textLin, Vernon W., Christine M. Gall, and Ching-Yi Lin. "Poster 369: Ampakine Treatment Enhances Neurite Outgrowth." PM&R 2 (September 2010): S162—S163. http://dx.doi.org/10.1016/j.pmrj.2010.07.402.
Full textGreer, John J., and Jun Ren. "Ampakine therapy to counter fentanyl-induced respiratory depression." Respiratory Physiology & Neurobiology 168, no. 1-2 (2009): 153–57. http://dx.doi.org/10.1016/j.resp.2009.02.011.
Full textRadin, Daniel P., Yong-Xin Li, Gary Rogers, Richard Purcell, and Arnold Lippa. "Stargazin differentially modulates ampakine gating kinetics and pharmacology." Biochemical Pharmacology 148 (February 2018): 308–14. http://dx.doi.org/10.1016/j.bcp.2018.01.019.
Full textIngvar, Martin, Jose Ambros-Ingerson, Mike Davis, et al. "Enhancement by an Ampakine of Memory Encoding in Humans." Experimental Neurology 146, no. 2 (1997): 553–59. http://dx.doi.org/10.1006/exnr.1997.6581.
Full textDavis-Reyes, Brionna D., Ashley E. Smith, Jimin Xu, Kathryn A. Cunningham, Jia Zhou, and Noelle C. Anastasio. "Subanesthetic ketamine with an AMPAkine attenuates motor impulsivity in rats." Behavioural Pharmacology 32, no. 4 (2021): 335–44. http://dx.doi.org/10.1097/fbp.0000000000000623.
Full textArai, A., and M. Kessler. "Pharmacology of Ampakine Modulators: From AMPA Receptors to Synapses and Behavior." Current Drug Targets 8, no. 5 (2007): 583–602. http://dx.doi.org/10.2174/138945007780618490.
Full textRadin, Daniel P., Sheng Zhong, Richard Purcell, and Arnold Lippa. "Acute ampakine treatment ameliorates age-related deficits in long-term potentiation." Biomedicine & Pharmacotherapy 84 (December 2016): 806–9. http://dx.doi.org/10.1016/j.biopha.2016.10.016.
Full textDai, Wei, Dian Xiao, Xiang Gao, et al. "A brain-targeted ampakine compound protects against opioid-induced respiratory depression." European Journal of Pharmacology 809 (August 2017): 122–29. http://dx.doi.org/10.1016/j.ejphar.2017.05.025.
Full textRen, Jun, Floriane Lenal, Michael Yang, Xiuqing Ding, and John J. Greer. "Coadministration of the AMPAKINE CX717 with Propofol Reduces Respiratory Depression and Fatal Apneas." Anesthesiology 118, no. 6 (2013): 1437–45. http://dx.doi.org/10.1097/aln.0b013e318291079c.
Full textWesensten, Nancy J., Rebecca M. Reichardt, and Thomas J. Balkin. "Ampakine (CX717) Effects on Performance and Alertness During Simulated Night Shift Work." Aviation, Space, and Environmental Medicine 78, no. 10 (2007): 937–43. http://dx.doi.org/10.3357/asem.2055.2007.
Full textSamartgis, Jodi R., Leslie Schachte, Agnes Hazi, and Simon F. Crowe. "Piracetam, an AMPAkine drug, facilitates memory consolidation in the day-old chick." Pharmacology Biochemistry and Behavior 103, no. 2 (2012): 353–58. http://dx.doi.org/10.1016/j.pbb.2012.08.014.
Full textSilverman, J. L., C. F. Oliver, M. N. Karras, P. T. Gastrell, and J. N. Crawley. "AMPAKINE enhancement of social interaction in the BTBR mouse model of autism." Neuropharmacology 64 (January 2013): 268–82. http://dx.doi.org/10.1016/j.neuropharm.2012.07.013.
Full textThakre, Prajwal P., Raphael R. Perim, Michael D. Sunshine, Arash Tadjalli, Gordon S. Mitchell, and David D. Fuller. "Spinal delivery of ampakine CX717 impacts phrenic motor output in adult rats." FASEB Journal 34, S1 (2020): 1. http://dx.doi.org/10.1096/fasebj.2020.34.s1.04037.
Full textLauterborn, Julie C., Linda C. Palmer, Yousheng Jia, et al. "Chronic Ampakine Treatments Stimulate Dendritic Growth and Promote Learning in Middle-Aged Rats." Journal of Neuroscience 36, no. 5 (2016): 1636–46. http://dx.doi.org/10.1523/jneurosci.3157-15.2016.
Full textRen, Jun, Xiuqing Ding, Gregory D. Funk, and John J. Greer. "Ampakine CX717 Protects against Fentanyl-induced Respiratory Depression and Lethal Apnea in Rats." Anesthesiology 110, no. 6 (2009): 1364–70. http://dx.doi.org/10.1097/aln.0b013e31819faa2a.
Full textXiao, Dian, Fei Xie, Xin Xu, and Xinbo Zhou. "The impact and mechanism of ampakine CX1739 on protection against respiratory depression in rats." Future Medicinal Chemistry 12, no. 23 (2020): 2093–104. http://dx.doi.org/10.4155/fmc-2020-0256.
Full textZheng, Yiwen, Sangeeta Balabhadrapatruni, Chisako Masumura, Cynthia L. Darlington, and Paul F. Smith. "Effects of the Putative Cognitive-Enhancing Ampakine, CX717, on Attention and Object Recognition Memory." Current Alzheimer Research 8, no. 8 (2011): 876–82. http://dx.doi.org/10.2174/156720511798192709.
Full textSimmons, Danielle A., Rishi A. Mehta, Julie C. Lauterborn, Christine M. Gall, and Gary Lynch. "Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice." Neurobiology of Disease 41, no. 2 (2011): 436–44. http://dx.doi.org/10.1016/j.nbd.2010.10.015.
Full textGoff, Donald C., Leslie Leahy, Ileana Berman, et al. "A Placebo-Controlled Pilot Study of the Ampakine CX516 Added to Clozapine in Schizophrenia." Journal of Clinical Psychopharmacology 21, no. 5 (2001): 484–87. http://dx.doi.org/10.1097/00004714-200110000-00005.
Full textSchitine, Clarissa, Sara Xapelli, Fabienne Agasse, et al. "Ampakine CX546 increases proliferation and neuronal differentiation in subventricular zone stem/progenitor cell cultures." European Journal of Neuroscience 35, no. 11 (2012): 1672–83. http://dx.doi.org/10.1111/j.1460-9568.2012.08072.x.
Full textLorier, Amanda R., Gregory D. Funk, and John J. Greer. "Opiate-Induced Suppression of Rat Hypoglossal Motoneuron Activity and Its Reversal by Ampakine Therapy." PLoS ONE 5, no. 1 (2010): e8766. http://dx.doi.org/10.1371/journal.pone.0008766.
Full textRadin, Daniel P., Steven Johnson, Richard Purcell, and Arnold S. Lippa. "Effects of chronic systemic low-impact ampakine treatment on neurotrophin expression in rat brain." Biomedicine & Pharmacotherapy 105 (September 2018): 540–44. http://dx.doi.org/10.1016/j.biopha.2018.06.008.
Full textXiao, Dian, Fan-Hua Meng, Wei Dai, et al. "Design, Synthesis and Biological Evaluation of Brain-Targeted Thiamine Disulfide Prodrugs of Ampakine Compound LCX001." Molecules 21, no. 4 (2016): 488. http://dx.doi.org/10.3390/molecules21040488.
Full textLipina, Tatiana, Karin Weiss, and John Roder. "The Ampakine CX546 Restores the Prepulse Inhibition and Latent Inhibition Deficits in mGluR5-Deficient Mice." Neuropsychopharmacology 32, no. 4 (2006): 745–56. http://dx.doi.org/10.1038/sj.npp.1301191.
Full textWezenberg, Elke, Robert Jan Verkes, Ge S. F. Ruigt, Wouter Hulstijn, and Bernard G. C. Sabbe. "Acute Effects of the Ampakine Farampator on Memory and Information Processing in Healthy Elderly Volunteers." Neuropsychopharmacology 32, no. 6 (2006): 1272–83. http://dx.doi.org/10.1038/sj.npp.1301257.
Full textGoff, Donald C., J. Steven Lamberti, Andrew C. Leon, et al. "A Placebo-Controlled Add-On Trial of the Ampakine, CX516, for Cognitive Deficits in Schizophrenia." Neuropsychopharmacology 33, no. 3 (2007): 465–72. http://dx.doi.org/10.1038/sj.npp.1301444.
Full textGordillo-Salas, M., J. Ren, J. J. Greer, and A. Adell. "The ampakine CX717 has a rapid, but short-lasting antidepressant-like activity in the rat." European Neuropsychopharmacology 29 (2019): S236—S237. http://dx.doi.org/10.1016/j.euroneuro.2018.11.380.
Full textClarkson, Andrew N., Kim Parker, Michael Nilsson, F. Rohan Walker, and Emma K. Gowing. "Combined Ampakine and BDNF Treatments Enhance Poststroke Functional Recovery in Aged Mice via AKT-CREB Signaling." Journal of Cerebral Blood Flow & Metabolism 35, no. 8 (2015): 1272–79. http://dx.doi.org/10.1038/jcbfm.2015.33.
Full textSimmons, D. A., C. S. Rex, L. Palmer, et al. "Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice." Proceedings of the National Academy of Sciences 106, no. 12 (2009): 4906–11. http://dx.doi.org/10.1073/pnas.0811228106.
Full textHampson, R. E., R. A. España, G. A. Rogers, L. J. Porrino, and S. A. Deadwyler. "Mechanisms underlying cognitive enhancement and reversal of cognitive deficits in nonhuman primates by the ampakine CX717." Psychopharmacology 202, no. 1-3 (2008): 355–69. http://dx.doi.org/10.1007/s00213-008-1360-z.
Full textKanju, Patrick M., Kodeeswaran Parameshwaran, Catrina Sims, Ben A. Bahr, Brian C. Shonesy, and Vishnu Suppiramaniam. "Ampakine CX516 ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation." Experimental Neurology 214, no. 1 (2008): 55–61. http://dx.doi.org/10.1016/j.expneurol.2008.07.010.
Full textKariharan, Thiruchelvam, Brian C. Shonesy, Koodeswaran Parameshwaran, and Vishnu D. Suppiramaniam. "P2-440: A memory enhancing drug ampakine (CX-717) potentially modulates synaptic AMPA receptor channel properties." Alzheimer's & Dementia 4 (July 2008): T502. http://dx.doi.org/10.1016/j.jalz.2008.05.1519.
Full textHampson, Robert E., Gary Rogers, Gary Lynch, and Sam A. Deadwyler. "Facilitative Effects of the Ampakine CX516 on Short-Term Memory in Rats: Correlations with Hippocampal Neuronal Activity." Journal of Neuroscience 18, no. 7 (1998): 2748–63. http://dx.doi.org/10.1523/jneurosci.18-07-02748.1998.
Full textRana, Sabhya, Michael D. Sunshine, and David D. Fuller. "Impact of Ampakine CX‐717 on Diaphragm EMG Activity and Breathing in Non‐anesthetized Freely Behaving Rats." FASEB Journal 34, S1 (2020): 1. http://dx.doi.org/10.1096/fasebj.2020.34.s1.09742.
Full textHardouin, Christophe, Frédéric Pin, Jean-François Giffard, et al. "Large Scale Synthesis of an Ampakine-type Active Pharmaceutical Ingredient Based on a Telescoped Regioselective Double Amidation Reaction." Organic Process Research & Development 23, no. 9 (2019): 1932–47. http://dx.doi.org/10.1021/acs.oprd.9b00241.
Full textMarenco, Stefano, Michael F. Egan, Terry E. Goldberg, et al. "Preliminary experience with an ampakine (CX516) as a single agent for the treatment of schizophrenia: a case series." Schizophrenia Research 57, no. 2-3 (2002): 221–26. http://dx.doi.org/10.1016/s0920-9964(01)00311-5.
Full textBoyle, Julia, Neil Stanley, Lynette M. James, et al. "Acute sleep deprivation: the effects of the AMPAKINE compound CX717 on human cognitive performance, alertness and recovery sleep." Journal of Psychopharmacology 26, no. 8 (2011): 1047–57. http://dx.doi.org/10.1177/0269881111405353.
Full textOertel, B. G., L. Felden, P. V. Tran, et al. "Selective Antagonism of Opioid-Induced Ventilatory Depression by an Ampakine Molecule in Humans Without Loss of Opioid Analgesia." Clinical Pharmacology & Therapeutics 87, no. 2 (2009): 204–11. http://dx.doi.org/10.1038/clpt.2009.194.
Full textArai, Amy C., Markus Kessler, Gary Rogers, and Gary Lynch. "Effects of the Potent Ampakine CX614 on Hippocampal and Recombinant AMPA Receptors: Interactions with Cyclothiazide and GYKI 52466." Molecular Pharmacology 58, no. 4 (2000): 802–13. http://dx.doi.org/10.1124/mol.58.4.802.
Full textSuppiramaniam, Vishnu, Ben A. Bahr, Srikumar Sinnarajah, et al. "Member of the Ampakine class of memory enhancers prolongs the single channel open time of reconstituted AMPA receptors." Synapse 40, no. 2 (2001): 154–58. http://dx.doi.org/10.1002/syn.1037.
Full textPalmer, Linda C., Ursula S. Hess, John Larson, Gary A. Rogers, Christine M. Gall, and Gary Lynch. "Comparison of the effects of an ampakine with those of methamphetamine on aggregate neuronal activity in cortex versus striatum." Molecular Brain Research 46, no. 1-2 (1997): 127–35. http://dx.doi.org/10.1016/s0169-328x(96)00280-x.
Full textHampson, Robert E., Gary Rogers, Gary Lynch, and Sam A. Deadwyler. "Facilitative Effects of the Ampakine CX516 on Short-Term Memory in Rats: Enhancement of Delayed-Nonmatch-to-Sample Performance." Journal of Neuroscience 18, no. 7 (1998): 2740–47. http://dx.doi.org/10.1523/jneurosci.18-07-02740.1998.
Full textHaw, Anna J., Leith CR Meyer, John J. Greer, and Andrea Fuller. "Ampakine CX1942 attenuates opioid-induced respiratory depression and corrects the hypoxaemic effects of etorphine in immobilized goats ( Capra hircus )." Veterinary Anaesthesia and Analgesia 43, no. 5 (2016): 528–38. http://dx.doi.org/10.1111/vaa.12358.
Full textPellerin, Luc, and Pierre J. Magistretti. "Ampakine CX546 bolsters energetic response of astrocytes: A novel target for cognitive-enhancing drugs acting as AMPA receptor modulators." Journal of Cerebral Blood Flow & Metabolism 25, no. 1_suppl (2005): S70. http://dx.doi.org/10.1038/sj.jcbfm.9591524.0070.
Full textChang, Philip K. Y., George A. Prenosil, David Verbich, Raminder Gill, and R. Anne McKinney. "Prolonged ampakine exposure prunes dendritic spines and increases presynaptic release probability for enhanced long-term potentiation in the hippocampus." European Journal of Neuroscience 40, no. 5 (2014): 2766–76. http://dx.doi.org/10.1111/ejn.12638.
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