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Relevant bibliographies by topics / Amphibian skin secretions

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Academic literature on the topic 'Amphibian skin secretions'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Amphibian skin secretions"

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CHEN, Tianbao, Susan FARRAGHER, Anthony J. BJOURSON, David F. ORR, Pingfan RAO, and Chris SHAW. "Granular gland transcriptomes in stimulated amphibian skin secretions." Biochemical Journal 371, no. 1 (2003): 125–30. http://dx.doi.org/10.1042/bj20021343.

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Amphibian defensive skin secretions are complex, species-specific cocktails of biologically active molecules, including many uncharacterized peptides. The study of such secretions for novel peptide discovery is time-limited, as amphibians are in rapid global decline. While secretion proteome analysis is non-lethal, transcriptome analysis has until now required killing of specimens prior to skin dissection for cDNA library construction. Here we present the discovery that polyadenylated mRNAs encoding dermal granular gland peptides are present in defensive skin secretions, stabilized by endogeno

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Indriani, Sylvia, Supatra Karnjanapratum, Nilesh Prakash Nirmal, and Sitthipong Nalinanon. "Amphibian Skin and Skin Secretion: An Exotic Source of Bioactive Peptides and Its Application." Foods 12, no. 6 (2023): 1282. http://dx.doi.org/10.3390/foods12061282.

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Amphibians have been consumed as an alternative protein source all around the world due to their delicacy. The skin of edible amphibians, particularly frogs and giant salamanders, always goes to waste without further utilization. However, these wastes can be utilized to extract protein and bioactive peptides (BPs). Various BPs have been extracted and reported for numerous biological activities such as antioxidant, antimicrobial, anticancer, antidiabetic, etc. The main BPs identified were brevinins, bombesins, dermaseptins, esculentins, magainin, temporins, tigerinins, and salamandrins. This re

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Nikolaieva, I. "AMPHIBIAN SKIN SECRETIONS: A POTENTIAL SOURCE OF PROTEOLYTIC ENZYMES." Biotechnologia Acta 11, no. 5 (2018): 42–48. http://dx.doi.org/10.15407/biotech11.05.042.

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Kyriachenko, Y., O. Oskyrko, I. Udovychenko, and T. Halenova. "Hemolytic activity of skin secretions of amphibians that inhabit the Ukraine territory." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology 80, no. 1 (2020): 6–10. http://dx.doi.org/10.17721/1728_2748.2020.80.6-10.

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Secretions derived from amphibian skin glands serve as a potential reservoir of various valuable active molecules. Currently, the multiple substances with diverse therapeutic activities among the components of glandular secretions of different species of amphibians have been found. It has been proven that they have antibacterial, antifungal, antiprotozoal, antidiabetic, antineoplastic, analgesic, and sleep-inducing properties. Taking this into consideration, to get the basic knowledge about the properties of the components of skin secretions of some Anura species that inhabit the territory of

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Cao, Xiaoqing, Jing Tang, Zhe Fu, et al. "Identification and Characterization of a Novel Gene-encoded Antioxidant Peptide from Odorous Frog Skin." Protein & Peptide Letters 26, no. 3 (2019): 160–69. http://dx.doi.org/10.2174/0929866525666181114153136.

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Background: Amphibian skin plays an essential role in protecting organisms from harmful external factors such as UV radiation. How amphibians protect themselves from reactive oxygen species following long-term sun exposure is an important and interesting question. Amphibian skins possess a novel antioxidant system composed of various Antioxidant Peptides (AOPs), which maintain redox homeostasis. However, only a few AOPs have been identified so far. Methods: Using combinational methods of peptidomics and genomics, we characterized a novel gene-encoded antioxidant peptide (herein named OA-VI12)

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Evans, Christine M., and Edmund D. Brodie. "Adhesive Strength of Amphibian Skin Secretions." Journal of Herpetology 28, no. 4 (1994): 499. http://dx.doi.org/10.2307/1564965.

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Udovychenko, I., D. Oliynyk, J. Dudkina, T. Halenova, and O. Savchuk. "Analysis of the common spadefoot toad (PELOBATES FUSCUS) skin secretions on the presence of the potential hemostasis system effectors." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology 77, no. 1 (2019): 38–44. http://dx.doi.org/10.17721/1728_2748.2019.77.38-44.

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Since nowadays the chemical synthesis of new bioactive compounds is a complicated and expensive procedure, alongside with the increased price for drugs based on synthetic biologically active compounds, scientists lay emphasize on natural sources as a promising raw material for various biologically active substances. Amphibian skin glands secretions are a powerful source of potential pharmacological agents. Currently their antimicrobial, antiviral, cardiotonic and antidiabetic activities have been studied in detail, although almost nothing is known about the effects of the tailless amphibians'

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Kwok, Hang Fai, Tianbao Chen, Craig Ivanyi, and Chris Shaw. "DNA in Amphibian and Reptile Venom Permits Access to Genomes without Specimen Sacrifice." Genomics Insights 1 (January 2008): GEI.S1039. http://dx.doi.org/10.4137/gei.s1039.

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Amphibian defensive skin secretions and reptile venoms are rich sources of bioactive peptides with potential pharmacological/pharmaceutical applications. As amphibian and reptile populations are in rapid global decline, our research group has been developing analytical methods that permit generation of robust molecular data from non-invasive skin secretion samples and venom samples. While previously we have demonstrated that parallel proteome and venom gland transcriptome analyses can be performed on such samples, here we report the presence of DNA that facilitates the more widely-used applica

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Ramsey, Jeremy P., Laura K. Reinert, Laura K. Harper, Douglas C. Woodhams, and Louise A. Rollins-Smith. "Immune Defenses against Batrachochytrium dendrobatidis, a Fungus Linked to Global Amphibian Declines, in the South African Clawed Frog, Xenopus laevis." Infection and Immunity 78, no. 9 (2010): 3981–92. http://dx.doi.org/10.1128/iai.00402-10.

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ABSTRACT Batrachochytrium dendrobatidis is a chytrid fungus that causes the lethal skin disease chytridiomycosis in amphibians. It is regarded as an emerging infectious disease affecting diverse amphibian populations in many parts of the world. Because there are few model amphibian species for immunological studies, little is known about immune defenses against B. dendrobatidis. We show here that the South African clawed frog, Xenopus laevis, is a suitable model for investigating immunity to this pathogen. After an experimental exposure, a mild infection developed over 20 to 30 days and declin

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Lin, Yan, Nan Hu, Haoyang He, et al. "A Hylarana latouchii Skin Secretion-Derived Novel Bombesin-Related Pentadecapeptide (Ranatensin-HLa) Evoke Myotropic Effects on the in vitro Rat Smooth Muscles." Toxins 11, no. 4 (2019): 204. http://dx.doi.org/10.3390/toxins11040204.

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Amphibians have developed successful defensive strategies for combating predators and invasive microorganisms encountered in their broad range of environments, which involve secretion of complex cocktails of noxious, toxic and diverse bioactive molecules from the skins. In recent years, amphibian skin secretions have been considered as an extraordinary warehouse for the discovery of therapeutic medicines. In this study, through bioactivity screening of the Hylarana latouchii skin secretion-derived fractions, a novel peptide belonging to ranatensin subfamily (ranatensin-HLa) was discovered, and

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Dissertations / Theses on the topic "Amphibian skin secretions"

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Clark, V. C. "The chemistry of amphibian skin secretions." Thesis, Queen's University Belfast, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546030.

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Shi, Daning. "Functional studies on the peptides from amphibian skin secretions." Thesis, Queen's University Belfast, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711901.

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Therapeutic peptides are continuing to grow in prominence among pharmaceutical manufacturers. Drugs based on peptides offer lower toxicity, show higher specificity, and demonstrate fewer toxicology issues than small molecule drugs. The specificity of peptides has tremendous clinical value and makes them very attractive and potentially lucrative therapeutics. In order to protect themselves from a great variety of potential predators, amphibians have evolved different morphological, physiological and behavioural features. One such defence mechanism is the secretion from granular skin glands. Fro

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Farragher, Susan. "Study of peptide transcripts in the skin and stimulated skin secretions of three different species of amphibians." Thesis, University of Ulster, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.232839.

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Gao, Yitian. "Peptidomic and bioinformatic studies on bioactive peptides from amphibian skin secretions." Thesis, Queen's University Belfast, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.726351.

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Phyllomedusa, as a significant genus of South American and Neotropical hylid frogs, has been researched for several years and this has produced abundant bioactive peptides. Most frog species have poisonous skin secretions that can act as a defence against potential predators and pathogens. Therefore, Phyllomedusa frogs have been referred to as a "treasure store” and compared to be the most promising drug sources. Antimicrobial peptides (AMPs), as the most widely isolated group of peptides from skin secretions of Phyllomedusa frogs, have been considered as a novel therapeutic approach to addres

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Chen, Dong. "Identification, molecular cloning and functional characterisation of novel bioactive peptide drugs from amphibian skin secretions." Thesis, Queen's University Belfast, 2017. https://pure.qub.ac.uk/portal/en/theses/identification-molecular-cloning-and-functional-characterisation-of-novel-bioactive-peptide-drugs-from-amphibian-skin-secretions(a5d6ffd1-1440-4528-af7a-4f6d9e244f76).html.

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Skin secretions of amphibians, which contain a large amount of bioactive compounds, play an essential role in their survival. For instance, some toxic or irritant secretions can protect them against predators. Due to the pharmacological and bioactive characteristics of the components in amphibian skin secretion, these secretions have been considered as one of the world’s richest source of such agents. In this study, the skin secretions of the frogs Odorrana livida, Hylarana latouchii and Phyllomedusa sauvagii were collected from the dorsal surface and immediately frozen in liquid nitrogen. Aft

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Power, Gavin Jude. "Isolation, structural characterisation and mechanisms of action of novel insulin-releasing peptides from amphibian skin secretions." Thesis, University of Ulster, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.554281.

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Amphibian skin secretions are considered to be one of the richest resources of bioactive molecules in the animal kingdom for pharmaceutical prospecting. This thesis has investigated amphibian skin peptides of eight different species of anurans (frogs and toads) for insulin-releasing and anti-diabetic properties. The skins of Pseudis paradoxa, Hylarana guntheri, Hylomantis lemur and Leptodactylus laticeps, were tested for the presence of peptides with stimulatory effects on insulin-release from the clonal BRIN-BDll cell line. Upon purification of the skin secretions/extract, multiple insulin-re

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Wang, Lei. "Functional genomic studies on amphibian skin secretion." Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.517036.

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Pan, Hao. "Studies on novel bioactive peptides from the skin secretion of amphibians." Thesis, Queen's University Belfast, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709692.

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Over many decades, naturally-occurring substances have been considered as an integral part of the treatment of human diseases. Skin secretions from amphibians play an important role for sourcing such agents with therapeutic potential. Amongst all types of substances discovered from amphibian skin secretion, peptides represent a large family of bioactive molecules with distinctive biological functions. To date, more than 2000 host defence peptides have been studied and many of them possess antimicrobial, antifungal or anticancer properties. In the present study, bioactive peptides have been iso

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Hou, Xiaojuan. "Identification and molecular cloning of skin secretion peptides from selected Eurasian amphibians." Thesis, Queen's University Belfast, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680080.

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The skin secretions of amphibians are used as a chemical defence mechanism as protection against predators within their natural environments. Among the classes of compounds contained within the secretions, peptides with diverse bioactivities, such as antimicrobial and pharmacological, are generally the most abundant. Such peptides may have therapeutic potential. In particular, the antimicrobial peptides have their own advantages, when compared with conventional clinical antibiotics. Many scientists have thus been studying the biologically-active peptides of amphibian skin and attempting to ass

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Dong, Yanjing. "Identification, molecular cloning and functional characterization of novel bioactive peptides from amphibian skin secretion." Thesis, Queen's University Belfast, 2018. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766285.

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Books on the topic "Amphibian skin secretions"

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Farragher, Susan. Study of peptide transcripts in the skin and stimulated skin secretions of three different species of amphibians. The author], 2002.

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Book chapters on the topic "Amphibian skin secretions"

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Conlon, J. Michael, and Jérôme Leprince. "Identification and Analysis of Bioactive Peptides in Amphibian Skin Secretions." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-535-4_12.

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2

Kreil, Gunther. "Skin secretions of Xenopus laevis." In The Biology of Xenopus. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780198549741.003.0014.

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Abstract A variety of peptides, enzymes and other proteins have been isolated from skin secretions of Amphibia. Among the peptides at least three different groups can be discerned: (1) those with structural and functional homology to mammalian hormones and neurotransmitters; (2) antimicrobial peptides of different types, one being characterized by the propensity to form amphipathic helices; and (3) opioid peptides containing a D-amino acid essential for biological activity, for which no mammalian counterparts have so far been found. Of the first group, thyrotropin releasing hormone, caerulein

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