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Journal articles on the topic 'Amphiphilic cyclodextrins'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Varan, Gamze, Juan M. Benito, Carmen Ortiz Mellet, and Erem Bilensoy. "Development of polycationic amphiphilic cyclodextrin nanoparticles for anticancer drug delivery." Beilstein Journal of Nanotechnology 8 (July 13, 2017): 1457–68. http://dx.doi.org/10.3762/bjnano.8.145.

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Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum of cancers. To overcome its bioavailability problems arising from very poor aqueous solubility and tendency to recrystallize upon dilution, paclitaxel is commercially formulated with co-solvents such as Cremophor EL® that are known to cause serious side effects during chemotherapy. Amphiphilic cyclodextrins are favored oligosaccharides as drug delivery systems for anticancer drugs, having the ability to spontaneously form nanoparticles without surfactant or co-solvents. In the past few years, polycationic, amphiphilic cyclodextrins were introduced as effective agents for gene delivery in the form of nanoplexes. In this study, the potential of polycationic, amphiphilic cyclodextrin nanoparticles were evaluated in comparison to non-ionic amphiphilic cyclodextrins and core–shell type cyclodextrin nanoparticles for paclitaxel delivery to breast tumors. Pre-formulation studies were used as a basis for selecting the suitable organic solvent and surfactant concentration for the novel polycationic cyclodextrin nanoparticles. The nanoparticles were then extensively characterized with particle size distribution, polydispersity index, zeta potential, drug loading capacity, in vitro release profiles and cytotoxicity studies. Results: Paclitaxel-loaded cyclodextrin nanoparticles were obtained in the diameter range of 80−125 nm (depending on the nature of the cyclodextrin derivative) where the smallest diameter nanoparticles were obtained with polycationic (PC) βCDC6. A strong positive charge also helped to increase the loading capacity of the nanoparticles with paclitaxel up to 60%. Interestingly, cyclodextrin nanoparticles were able to stabilize paclitaxel in aqueous solution for 30 days. All blank cyclodextrin nanoparticles were demonstrated to be non-cytotoxic against L929 mouse fibroblast cell line. In addition, paclitaxel-loaded nanoparticles have a significant anticancer effect against MCF-7 human breast cancer cell line as compared with a paclitaxel solution in DMSO. Conclusion: According to the results of this study, both amphiphilic cyclodextrin derivatives provide suitable nanometer-sized drug delivery systems for safe and efficient intravenous paclitaxel delivery for chemotherapy. In the light of these studies, it can be said that amphiphilic cyclodextrin nanoparticles of different surface charge can be considered as a promising alternative for self-assembled nanometer-sized drug carrier systems for safe and efficient chemotherapy.

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2

Raffaini, Giuseppina, Antonino Mazzaglia, and Fabio Ganazzoli. "Aggregation behaviour of amphiphilic cyclodextrins: the nucleation stage by atomistic molecular dynamics simulations." Beilstein Journal of Organic Chemistry 11 (December 7, 2015): 2459–73. http://dx.doi.org/10.3762/bjoc.11.267.

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Amphiphilically modified cyclodextrins may form various supramolecular aggregates. Here we report a theoretical study of the aggregation of a few amphiphilic cyclodextrins carrying hydrophobic thioalkyl groups and hydrophilic ethylene glycol moieties at opposite rims, focusing on the initial nucleation stage in an apolar solvent and in water. The study is based on atomistic molecular dynamics methods with a “bottom up” approach that can provide important information about the initial aggregates of few molecules. The focus is on the interaction pattern of amphiphilic cyclodextrin (aCD), which may interact by mutual inclusion of the substituent groups in the hydrophobic cavity of neighbouring molecules or by dispersion interactions at their lateral surface. We suggest that these aggregates can also form the nucleation stage of larger systems as well as the building blocks of micelles, vesicle, membranes, or generally nanoparticles thus opening new perspectives in the design of aggregates correlating their structures with the pharmaceutical properties.

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3

Roux, Michel, Bruno Perly, and Florence Djedaïni-Pilard. "Self-assemblies of amphiphilic cyclodextrins." European Biophysics Journal 36, no. 8 (July 31, 2007): 861–67. http://dx.doi.org/10.1007/s00249-007-0207-6.

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4

Lumholdt, Ludmilla, Sophie Fourmentin, Thorbjørn T. Nielsen, and Kim L. Larsen. "Removal of volatile organic compounds using amphiphilic cyclodextrin-coated polypropylene." Beilstein Journal of Organic Chemistry 10 (November 24, 2014): 2743–50. http://dx.doi.org/10.3762/bjoc.10.290.

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Polypropylene nonwovens were functionalised using a self-assembled, amphiphilic cyclodextrin coating and the potential for water purification by removal of pollutants was studied. As benzene is one of the problematic compounds in the Water Framework Directive, six volatile organic compounds (benzene and five benzene-based substances) were chosen as model compounds. The compounds were tested as a mixture in order to provide a more realistic situation since the wastewater will be a complex mixture containing multiple pollutants. The volatile organic compounds are known to form stable inclusion complexes with cyclodextrins. Six different amphiphilic cyclodextrin derivatives were synthesised in order to elucidate whether or not the uptake abilities of the coating depend on the structure of the derivative. Headspace gas chromatography was used for quantification of the uptake exploiting the volatile nature of benzene and its derivatives. The capacity was shown to increase beyond the expected stoichiometries of guest–host complexes with ratios of up to 16:1.

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5

Coleman, Anthony W., and Athena Kasselouri. "Supramolecular assemblies based on amphiphilic cyclodextrins." Supramolecular Chemistry 1, no. 2 (February 1993): 155–61. http://dx.doi.org/10.1080/10610279308040661.

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6

Kawabata, Yasujiro, Mutsuyoshi Matsumoto, Takayoshi Nakamura, Motoo Tanaka, Eiichiro Manda, Hisao Takahashi, Shoji Tamura, Waichiro Tagaki, Hiroo Nakahara, and Kiyoshige Fukuda. "Langmuir-Blodgett films of amphiphilic cyclodextrins." Thin Solid Films 159, no. 1-2 (May 1988): 353–58. http://dx.doi.org/10.1016/0040-6090(88)90648-7.

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7

Cavalli, Roberta, Francesco Trotta, M. Eugenia Carlotti, Barbara Possetti, and Michele Trotta. "Nanoparticles derived from amphiphilic γ-cyclodextrins." Journal of Inclusion Phenomena and Macrocyclic Chemistry 57, no. 1-4 (January 19, 2007): 657–61. http://dx.doi.org/10.1007/s10847-006-9269-9.

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8

Kauscher, Ulrike, and Bart Jan Ravoo. "A self-assembled cyclodextrin nanocarrier for photoreactive squaraine." Beilstein Journal of Organic Chemistry 12 (November 25, 2016): 2535–42. http://dx.doi.org/10.3762/bjoc.12.248.

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Photoreactive squaraines produce cytotoxic oxygen species under irradiation and have significant potential for photodynamic therapy. Herein we report that squaraines can be immobilized on a self-assembled nanocarrier composed of amphiphilic cyclodextrins to enhance their photochemical activity. To this end, a squaraine was equipped with two adamantane moieties that act as anchors for the cyclodextrin vesicle surface. The supramolecular immobilization was monitored by using fluorescence spectroscopy and microscopy and the photochemistry of the squaraine was investigated by using absorption spectroscopy.

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9

Stepniak, Pawel, Bruno Lainer, Kazimierz Chmurski, and Janusz Jurczak. "pH-Controlled recognition of amino acids by urea derivatives of β-cyclodextrin." RSC Advances 7, no. 26 (2017): 15742–46. http://dx.doi.org/10.1039/c7ra02127e.

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10

Champagne, Pier-Luc, David Ester, Michael Zeeman, Carson Zellman, Vance E. Williams, and Chang-Chun Ling. "Inverting substitution patterns on amphiphilic cyclodextrins induces unprecedented formation of hexagonal columnar superstructures." Journal of Materials Chemistry C 5, no. 36 (2017): 9247–54. http://dx.doi.org/10.1039/c7tc02636f.

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11

Baâzaoui, Mondher, Ines Béjaoui, Rafik Kalfat, Noureddine Amdouni, Souhaira Hbaieb, and Yves Chevalier. "Interfacial properties and thermodynamic behavior of cationic amphiphilic β-cyclodextrins substituted with one or seven alkyl chains." RSC Advances 6, no. 76 (2016): 72044–54. http://dx.doi.org/10.1039/c6ra10597a.

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12

Ward, Sandra, Oliver Calderon, Ping Zhang, Matthew Sobchuk, Samantha N. Keller, Vance E. Williams, and Chang-Chun Ling. "Investigation into the role of the hydrogen bonding network in cyclodextrin-based self-assembling mesophases." J. Mater. Chem. C 2, no. 25 (2014): 4928–36. http://dx.doi.org/10.1039/c4tc00448e.

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13

Miao, Yong, Florence Djedaïni-Pilard, and Véronique Bonnet. "A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes." Beilstein Journal of Organic Chemistry 10 (November 12, 2014): 2654–57. http://dx.doi.org/10.3762/bjoc.10.278.

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This work reports the synthesis of a new family of mono-substituted amphiphilic cyclodextrins using a green methodology. Reactions using greener and safer catalysts with more environmentally friendly purification solvents were performed. Four unreported mono-substituted cyclodextrins bearing a phytosphingolipidyl chain and a fatty acid chain (C10, C12, C14 and C18) were successfully obtained with a promising yield.

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14

Ling, Chang-Chun, Raphael Darcy, and Wilhelm Risse. "Cyclodextrin liquid crystals: synthesis and self-organisation of amphiphilic thio-β-cyclodextrins." J. Chem. Soc., Chem. Commun., no. 5 (1993): 438–40. http://dx.doi.org/10.1039/c39930000438.

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15

Foschi, Giulia, Francesca Leonardi, Angela Scala, Fabio Biscarini, Alessandro Kovtun, Andrea Liscio, Antonino Mazzaglia, and Stefano Casalini. "Electrical release of dopamine and levodopa mediated by amphiphilic β-cyclodextrins immobilized on polycrystalline gold." Nanoscale 7, no. 47 (2015): 20025–32. http://dx.doi.org/10.1039/c5nr05405b.

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16

Collot, Mayeul, Maria Isabel Garcia-Moreno, Christophe Fajolles, Michel Roux, Laurent Mauclaire, and Jean-Maurice Mallet. "Bis antennae amphiphilic cyclodextrins: the first examples." Tetrahedron Letters 48, no. 48 (November 2007): 8566–69. http://dx.doi.org/10.1016/j.tetlet.2007.09.020.

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17

Perret, Florent, and Helene Parrot-Lopez. "ChemInform Abstract: Amphiphilic Cyclodextrins: Synthesis and Characterization." ChemInform 43, no. 3 (December 22, 2011): no. http://dx.doi.org/10.1002/chin.201203218.

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18

Kasselouri, Athena, Anthony William Coleman, and Adam Baszkin. "Mixed Monolayers of Amphiphilic Cyclodextrins and Phospholipids." Journal of Colloid and Interface Science 180, no. 2 (June 1996): 384–97. http://dx.doi.org/10.1006/jcis.1996.0317.

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19

Kasselouri, Athena, Anthony William Coleman, Geneviève Albrecht, and Adam Baszkin. "Mixed Monolayers of Amphiphilic Cyclodextrins and Phospholipids." Journal of Colloid and Interface Science 180, no. 2 (June 1996): 398–404. http://dx.doi.org/10.1006/jcis.1996.0318.

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20

Bilensoy, Erem. "Nanoparticulate Delivery Systems Based on Amphiphilic Cyclodextrins." Journal of Biomedical Nanotechnology 4, no. 3 (September 1, 2008): 293–303. http://dx.doi.org/10.1166/jbn.2008.323.

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21

Takisawa, N., K. Shirahama, and I. Tanaka. "Interactions of amphiphilic drugs with?-,?-, and?-cyclodextrins." Colloid & Polymer Science 271, no. 5 (May 1993): 499–506. http://dx.doi.org/10.1007/bf00657395.

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22

Favrelle, Audrey, Véronique Bonnet, Catherine Sarazin, and Florence Djedaïni-Pilard. "Novel chemo-enzymatic access to amphiphilic cyclodextrins." Journal of Inclusion Phenomena and Macrocyclic Chemistry 57, no. 1-4 (January 24, 2007): 15–20. http://dx.doi.org/10.1007/s10847-006-9167-1.

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23

Méndez-Ardoy, Alejandro, Alejandro Díaz-Moscoso, Carmen Ortiz Mellet, Christophe Di Giorgio, Pierre Vierling, Juan M. Benito, and José M. García Fernández. "Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery." RSC Advances 5, no. 93 (2015): 76464–71. http://dx.doi.org/10.1039/c5ra16087a.

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24

Lourenço, Leandro M. O., Patrícia M. R. Pereira, Elisabete Maciel, Mónica Válega, Fernando M. J. Domingues, Maria R. M. Domingues, Maria G. P. M. S. Neves, José A. S. Cavaleiro, Rosa Fernandes, and João P. C. Tomé. "Amphiphilic phthalocyanine–cyclodextrin conjugates for cancer photodynamic therapy." Chem. Commun. 50, no. 61 (2014): 8363–66. http://dx.doi.org/10.1039/c4cc02226b.

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25

Gu, Wen-Xing, Ying-Wei Yang, Jijie Wen, Hongguang Lu, and Hui Gao. "Construction of reverse vesicles from pseudo-graft poly(glycerol methacrylate)s via cyclodextrin–cholesterol interactions." Polym. Chem. 5, no. 21 (2014): 6344–49. http://dx.doi.org/10.1039/c4py00848k.

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Reverse vesicles were constructed from pseudo-graft amphiphilic copolymers by dint of the host–guest inclusion complexation between β-cyclodextrins and cholesterols, and transformed into organogels by adding trace amounts of water.

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26

Li, Pei-yu, Yong Chen, Chang-hui Chen, and Yu Liu. "Amphiphilic multi-charged cyclodextrins and vitamin K co-assembly as a synergistic coagulant." Chemical Communications 55, no. 78 (2019): 11790–93. http://dx.doi.org/10.1039/c9cc06545h.

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27

Harada, Akira, Hiromichi Okumura, Miyuko Okada, Syukuko Suzuki, and Mikiharu Kamachi. "Site-Selective Complexation of Amphiphilic Compounds by Cyclodextrins." Chemistry Letters 29, no. 5 (May 2000): 548–49. http://dx.doi.org/10.1246/cl.2000.548.

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28

Zagami, Roberto, Valentina Rapozzi, Anna Piperno, Angela Scala, Claudia Triolo, Mariachiara Trapani, Luigi E. Xodo, Luigi Monsù Scolaro, and Antonino Mazzaglia. "Folate-Decorated Amphiphilic Cyclodextrins as Cell-Targeted Nanophototherapeutics." Biomacromolecules 20, no. 7 (June 7, 2019): 2530–44. http://dx.doi.org/10.1021/acs.biomac.9b00306.

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29

de Rossi, Rita H., O. Fernando Silva, Raquel V. Vico, and Carlos J. Gonzalez. "Molecular organization and recognition properties of amphiphilic cyclodextrins." Pure and Applied Chemistry 81, no. 4 (January 1, 2009): 755–65. http://dx.doi.org/10.1351/pac-con-08-08-13.

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The continuing challenge of using cyclodextrins (CDs) for solubilization and drug targeting has led to the preparation of a wide variety of chemically modified derivatives in order to improve the properties of these host molecules. A possible approach for pharmaceutical applications would be to combine the recognition specificity of CDs with the transport properties of organized structures such as vesicles, liposomes, or micelles. Amphiphilic CDs can be admixed to phospholipid monolayers and to liposomes, and they can be dispersed into nanospheres showing promising properties for drug encapsulation. Monoacylated derivatives of β-CD, Mod-CD (Cn), were synthesized in our laboratory from the reaction of alkenyl succinic anhydride with β-CD. We found that the compound with 10 carbon atoms in the alkenyl chain, Mod-CD (C10), can be incorporated into inverted micelles. We studied their properties in solution and at the air-water interface. In solution they have very low critical micellar concentration, and in the aggregates there are two recognition sites: one is the cavity of the CD and the other is formed by the hydrophobic tails. The alkenyl chain interacts with the cavity, but this is not an obstacle for the association with external guests such as 1-amino adamantane, phenolphthalein, or Prodan. Mod-CD (Cn) with n equal to 10, 14, and 16 (n indicates the number of carbons in the alkenyl chain), form stable monolayers at the air-water interface and they adopt an organization very different from those found for persubstituted CDs. The differences are attributed to the higher conformational flexibility of these compounds, which allows the organization of the CD units with the cavity perpendicular to the interface.

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30

Sallas, Florence, and Raphael Darcy. "Amphiphilic Cyclodextrins – Advances in Synthesis and Supramolecular Chemistry." European Journal of Organic Chemistry 2008, no. 6 (February 2008): 957–69. http://dx.doi.org/10.1002/ejoc.200700933.

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31

Schalchli, A., J. J. Benattar, P. Tchoreloff, P. Zhang, and A. W. Coleman. "Structure of a monomolecular layer of amphiphilic cyclodextrins." Langmuir 9, no. 8 (August 1993): 1968–70. http://dx.doi.org/10.1021/la00032a009.

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32

Grachev, M. K., S. V. Sipin, L. O. Kononov, and E. E. Nifant′ev. "Synthesis of amphiphilic glycophospholipids based on β-cyclodextrins." Russian Chemical Bulletin 58, no. 1 (January 2009): 223–29. http://dx.doi.org/10.1007/s11172-009-0033-3.

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33

Cocq, Aurélien, Hervé Bricout, Florence Djedaïni-Pilard, Sébastien Tilloy, and Eric Monflier. "Rhodium-Catalyzed Aqueous Biphasic Olefin Hydroformylation Promoted by Amphiphilic Cyclodextrins." Catalysts 10, no. 1 (January 1, 2020): 56. http://dx.doi.org/10.3390/catal10010056.

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Hydroformylation is an industrial process that allows for the production of aldehydes from alkenes using transition metals. The reaction can be carried out in water, and the catalyst may be recycled at the end of the reaction. The industrial application of rhodium-catalyzed aqueous hydroformylation has been demonstrated for smaller olefins (propene and butene). Unfortunately, larger olefins are weakly soluble in water, which results in very low catalytic activity. In an attempt to counteract this, we investigated the use of amphiphilic oleic succinyl-cyclodextrins (OS-CDs) synthesized from oleic acid derivatives and maleic anhydride. OS-CDs were found to increase the catalytic activity of rhodium during the hydroformylation of water-insoluble olefins, such as 1-decene and 1-hexadecene, by promoting mass transfer. Recyclability of the catalytic system was also evaluated in the presence of these cyclodextrins.

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34

Dubes, Alix, Hélène Parrot-Lopez, Patrick Shahgaldian, and Anthony W. Coleman. "Interfacial interactions between amphiphilic cyclodextrins and physiologically relevant cations." Journal of Colloid and Interface Science 259, no. 1 (March 2003): 103–11. http://dx.doi.org/10.1016/s0021-9797(02)00067-x.

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35

Chmurski, Kazimierz, Antony W. Coleman, and Janusz Jurczak. "Direct Synthesis of Amphiphilic α-, β-, and γ-Cyclodextrins." Journal of Carbohydrate Chemistry 15, no. 7 (September 1996): 787–96. http://dx.doi.org/10.1080/07328309608005692.

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36

Byrne, Colin, Florence Sallas, Dilip K. Rai, Julien Ogier, and Raphael Darcy. "Poly-6-cationic amphiphilic cyclodextrins designed for gene delivery." Organic & Biomolecular Chemistry 7, no. 18 (2009): 3763. http://dx.doi.org/10.1039/b907232b.

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37

McMahon, Anthony, Martin J. O'Neill, Eva Gomez, Ruth Donohue, Damien Forde, Raphael Darcy, and Caitriona M. O'Driscoll. "Targeted gene delivery to hepatocytes with galactosylated amphiphilic cyclodextrins." Journal of Pharmacy and Pharmacology 64, no. 8 (March 28, 2012): 1063–73. http://dx.doi.org/10.1111/j.2042-7158.2012.01497.x.

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38

Bauer, Martin, Christophe Fajolles, Thierry Charitat, Hanna Wacklin, and Jean Daillant. "Amphiphilic Behavior of New Cholesteryl Cyclodextrins: A Molecular Study." Journal of Physical Chemistry B 115, no. 51 (December 29, 2011): 15263–70. http://dx.doi.org/10.1021/jp205917q.

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39

Lumholdt, Ludmilla, Nielsen Thorbjørn Terndrup, and Larsen Kim Lambertsen. "Surface modification using self-assembled layers of amphiphilic cyclodextrins." Journal of Applied Polymer Science 131, no. 22 (June 13, 2014): n/a. http://dx.doi.org/10.1002/app.41047.

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40

Sultanem, Caroline, Stéphane Moutard, Jean-Jacques Benattar, Florence Djedaïni-Pilard, and Bruno Perly. "Hydration of Black Foam Films Made of Amphiphilic Cyclodextrins." Langmuir 20, no. 8 (April 2004): 3311–18. http://dx.doi.org/10.1021/la0364136.

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41

Cristiano, Antonella, Choon Woo Lim, Dorota I. Rozkiewicz, David N. Reinhoudt, and Bart Jan Ravoo. "Solid-Supported Monolayers and Bilayers of Amphiphilic β-Cyclodextrins." Langmuir 23, no. 17 (August 2007): 8944–49. http://dx.doi.org/10.1021/la700808h.

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42

Matsumoto, Mutsuyoshi, Motoo Tanaka, Reiko Azumi, Hiroaki Tachibana, Takayoshi Nakamura, Yasujiro Kawabata, Tomohiko Miyasaka, Waichiro Tagaki, Hiroo Nakahara, and Kiyoshige Fukuda. "Molecular recognition by amphiphilic cyclodextrins in Langmuir-Blodgett films." Thin Solid Films 210-211 (April 1992): 803–5. http://dx.doi.org/10.1016/0040-6090(92)90409-5.

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43

Kraus, Tomáš, Miloš Buděšínský, and Jiří Závada. "Novel Amphiphilic Cyclodextrins: Per[6-deoxy-6-(4,5-dicarboxy-1,2,3-triazol-1-yl)-2,3-di-O-methyl] Derivatives." Collection of Czechoslovak Chemical Communications 63, no. 4 (1998): 534–40. http://dx.doi.org/10.1135/cccc19980534.

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Per[6-deoxy-6-(4,5-dicarboxy-1,2,3-triazol-1-yl)-2,3-di-O-methyl] substituted α- and β-cyclodextrins 6a and 6b were prepared by 1,3-dipolar cycloaddition reaction of the corresponding per(6-azido-6-deoxy-2,3-di-O-methyl)cyclodextrins 4a and 4b with dimethyl acetylenedicarboxylate.

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44

Xie, Jun Peng, Wan Wan Ding, and Rui Fang Guan. "Preparation and Characterization of Inclusion Complexes between Cyclodextrin and Block Polyether Polysiloxanes." Advanced Materials Research 1089 (January 2015): 117–20. http://dx.doi.org/10.4028/www.scientific.net/amr.1089.117.

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A amphiphilic triblock copolymer, poly(ethylene oxide) -poly(dimethylsiloxane) -poly(ethylene oxide) (PEO-PDMS-PEO) was synthesized via a simple hydrosilylation reaction, and inclusion selective rule of cyclodextrins (α–CDand γ-CD) and PEO-PDMS-PEO to form inclusion complexes were discussed in this paper. Selective inclusion's impact on the triblock copolymer( PEO-PDMS-PEO) was studied.

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45

GUO, Wenyan, Minggang ZHAO, and Aiyou HAO. "Synthesis of Amphiphilic β-Cyclodextrins and Their Nanospheres in Water." Acta Agronomica Sinica 30, no. 3 (2013): 260. http://dx.doi.org/10.3724/sp.j.1095.2012.20164.

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46

Sun, Tao, Qie Guo, Cai Zhang, Jingcheng Hao, Pengyao Xing, Jie Su, Shangyang Li, Aiyou Hao, and Guangcun Liu. "Self-Assembled Vesicles Prepared from Amphiphilic Cyclodextrins as Drug Carriers." Langmuir 28, no. 23 (May 31, 2012): 8625–36. http://dx.doi.org/10.1021/la301497t.

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47

Kauscher, Ulrike, Marc C. A. Stuart, Patrick Drücker, Hans-Joachim Galla, and Bart Jan Ravoo. "Incorporation of Amphiphilic Cyclodextrins into Liposomes as Artificial Receptor Units." Langmuir 29, no. 24 (February 11, 2013): 7377–83. http://dx.doi.org/10.1021/la3045434.

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48

Niino, Hiroyuki, Akira Yabe, Akihiko Ouchi, Motoo Tanaka, Yasujiro Kawabata, Shoji Tamura, Tomohiro Miyasaka, Waichiro Tagaki, Hiroo Nakahara, and Kiyoshige Fukuda. "Stabilization of a Labile cis-Azobenzene Derivative with Amphiphilic Cyclodextrins." Chemistry Letters 17, no. 7 (July 5, 1988): 1227–30. http://dx.doi.org/10.1246/cl.1988.1227.

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49

Memişoğlu, Erem, Amélie Bochot, Murat Şen, Dominique Duchêne, and A. Atilla Hıncal. "Non-surfactant nanospheres of progesterone inclusion complexes with amphiphilic β-cyclodextrins." International Journal of Pharmaceutics 251, no. 1-2 (January 2003): 143–53. http://dx.doi.org/10.1016/s0378-5173(02)00593-8.

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50

黄, 健升. "The Synthesis of Biological Functional Amphiphilic Cyclodextrins and Its Research Progress." Journal of Organic Chemistry Research 01, no. 03 (2013): 13–17. http://dx.doi.org/10.12677/jocr.2013.13004.

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