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Journal articles on the topic 'AMX'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Kemit, Esibrena Br, Yermia S. Mokosuli, and Helen J. Lawalata. "Isolation, Identification and Antibacterial Testing, Indigenous Bacteria from Apis Mellifera's Honeycomb North Sumatra Origin." Jurnal Biologi Tropis 22, no. 3 (2022): 1069–76. http://dx.doi.org/10.29303/jbt.v22i3.4343.

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Honeycomb can be used as a source of antibacterial, this is due to the content of secondary metabolites in the form of flavonoids in the honeycomb which serves as a protective determinant of honey quality. This study aims to isolate, identify and test antibacterial isolates of Indigenous bacteria from Apis mellifera nests against gram-positive bacteria S. aureus and gram-negative bacteria E. coli. This research used descriptive method and the research data were obtained through laboratory experiments. The results of the isolation stage of indigenous bacteria obtained seven (7) isolates AM1, AM

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Montesano, M. A., G. L. Freeman, G. Gazzinelli, and D. G. Colley. "Immune responses during human Schistosoma mansoni. XVII. Recognition by monoclonal anti-idiotypic antibodies of several idiotopes on a monoclonal anti-soluble schistosomal egg antigen antibody and anti-soluble schistosomal egg antigen antibodies from patients with different clinical forms of infection." Journal of Immunology 145, no. 9 (1990): 3095–99. http://dx.doi.org/10.4049/jimmunol.145.9.3095.

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Abstract A monoclonal human anti-soluble schistosomal egg Ag(SEA) antibody (E5) that stimulates anti-Id T cells and is idiotypically represented in pools of immunoaffinity-purified human anti-SEA antibodies from chronic, generally asymptomatic, intestinal (INT) patients (AM1 and AM5) was used to raise several monoclonal anti-Id: 1C2, 1C6, 4A8, 4F9, and 2A7. Cross-inhibition between these anti-Id identified distinct idiotopes on E5. Anti-SEA preparations from schistosomiasis patients (AM1, AM5, and others) were tested for their inhibition of the E5/monoclonal anti-Id reactions, in competitive E

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3

Thorburn, Christine E., Sarah J. Knott та David I. Edwards. "In Vitro Activities of Oral β-Lactams at Concentrations Achieved in Humans against Penicillin-Susceptible and -Resistant Pneumococci and Potential to Select Resistance". Antimicrobial Agents and Chemotherapy 42, № 8 (1998): 1973–79. http://dx.doi.org/10.1128/aac.42.8.1973.

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ABSTRACT The β-lactam susceptibilities of 65 strains ofStreptococcus pneumoniae for which penicillin MICs covered a broad range were assessed. The order of potency was amoxicillin (AMX) = amoxicillin-clavulanate (AMC) > penicillin G > cefpodoxime (CPO) > cefuroxime (CXM) > cefprozil > cefaclor > loracarbef > cefixime. No decrease in susceptibility was seen following repeated subculture of two penicillin-susceptible strains of S. pneumoniae in AMX, AMC, cefaclor, or loracarbef, whereas repeated exposure to CPO and CXM resulted in 4- to 32-fold decreases in susceptibility fo

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4

Meyer Sauteur, Patrick M., Ariane Burkhard, Ueli Moehrlen, et al. "Pleural Tap-Guided Antimicrobial Treatment for Pneumonia with Parapneumonic Effusion or Pleural Empyema in Children: A Single-Center Cohort Study." Journal of Clinical Medicine 8, no. 5 (2019): 698. http://dx.doi.org/10.3390/jcm8050698.

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Parapneumonic effusion or pleural empyema (PPE/PE) is a frequent complication of community-acquired pneumonia (CAP) in children. Different management approaches exist for this condition. We evaluated a 14-day treatment with amoxicillin (AMX) with/without clavulanic acid (AMC) confirmed or modified by microbiological findings from pleural tap. Children ≤16 years of age with radiologically diagnosed PPE/PE and initial diagnostic pleural tap were included at University Children’s Hospital Zurich from 2001–2015. AMX/AMC was given for 14 days and rationalized according to microbiological pleural ta

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5

Mack, I., M. Sharland, S. Rehm, K. Rentsch, and J. Bielicki. "O25 Clavulanate stability in child-appropriate formulations is inadequate for use in treating young children in Asia." Archives of Disease in Childhood 104, no. 6 (2019): e11.1-e11. http://dx.doi.org/10.1136/archdischild-2019-esdppp.25.

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BackgroundAmoxicillin-clavulanate (AMC) is among the most frequently used antibiotic for paediatric infections globally. AMC child-appropriate formulations are largely limited to dry powder suspensions, which have to be stored refrigerated once reconstituted due to stability limitations of clavulanate.MethodsOral Amoxicillin (AMX) and AMC formulations were identified from IQVIA-MIDAS wholesale data, and 2015 antibiotic consumption in courses/1000 child-years was estimated in Bangladesh, India, Indonesia, Pakistan, Philippines and Vietnam with an assumed average treatment of 7 days. Costs per c

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6

Murphy, Adrian Gerard, Rory Casey, David William Fennelly, et al. "The effect of novel small molecule drugs in human explants across the disease sequence in colorectal cancer." Journal of Clinical Oncology 30, no. 15_suppl (2012): e13570-e13570. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e13570.

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e13570 Background: The treatment of metastatic colorectal cancer has been improved by combining cytotoxic chemotherapy with bevacizumab. Newer anti-angiogenic agents are required to improve survival rates as response rates with the current therapies are modest. The preclinical development of such drugs is time-consuming and new methods are required to test the efficacy of lead drugs which represent the entire tumor micro-environment. Methods: Chemical screens were performed in zebrafish larvae to identify hits that affected intersegmental angiogenesis. Five lead drugs were then tested for cyto

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7

Ogoshi, Maho, Shigenori Nobata, and Yoshio Takei. "Potent osmoregulatory actions of homologous adrenomedullins administered peripherally and centrally in eels." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 295, no. 6 (2008): R2075—R2083. http://dx.doi.org/10.1152/ajpregu.90688.2008.

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The teleost adrenomedullin (AM) family consists of three groups, AM1/AM4, AM2/AM3, and AM5. In the present study, we examined the effects of homologous AM1, AM2, and AM5 on drinking and renal function after peripheral or central administration in conscious freshwater eels. AM2 and AM5, but not AM1, exhibited dose-dependent (0.01–1 nmol/kg) dipsogenic and antidiuretic effects after intra-arterial bolus injection. The antidiuretic effect was significantly correlated with the degree of associated hypotension. To avoid the potential indirect osmoregulatory effects of AM-induced hypotension, infusi

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8

Abouyakob, Ousama, Mohammed Bourakba, Bernard P. A. Santen, and Roy P. Van Der Sluis. "‘Say on pay’ in Nederland: een analyse en een voorstel." Maandblad Voor Accountancy en Bedrijfseconomie 86, no. 11 (2012): 441–51. http://dx.doi.org/10.5117/mab.86.12876.

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In deze studie staat de ontwikkeling van bestuurdersbeloningen van aan de AEX en AMX genoteerde ondernemingen tussen 2002 en 2011 centraal. De vaste bestuurdersbeloningen in AMX-ondernemingen blijken twee keer zo snel te stijgen als cao– beloningen. Wettelijke en andere maatregelen om de stijging van bestuurdersbeloningen te beperken lijken daar niet effectief. Uit ons empirisch onderzoek komt een aantal mogelijke redenen naar voren waardoor deze maatregelen mogelijk niet altijd effectief zijn. Ten slotte worden maatregelen aanbevolen, waarmee effectievere invloed op de beloningsontwikkeling w

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9

Abouyakob, Ousama, Mohammed Bourakba, Bernard P. A. Santen, and Der Sluis Roy P. Van. "'Say on pay' in Nederland: een analyse en een voorstel." Maandblad Voor Accountancy en Bedrijfseconomie 86, no. (11) (2012): 441–51. https://doi.org/10.5117/mab.86.12876.

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In deze studie staat de ontwikkeling van bestuurdersbeloningen van aan de AEX en AMX genoteerde ondernemingen tussen 2002 en 2011 centraal. De vaste bestuurdersbeloningen in AMX-ondernemingen blijken twee keer zo snel te stijgen als cao– beloningen. Wettelijke en andere maatregelen om de stijging van bestuurdersbeloningen te beperken lijken daar niet effectief. Uit ons empirisch onderzoek komt een aantal mogelijke redenen naar voren waardoor deze maatregelen mogelijk niet altijd effectief zijn. Ten slotte worden maatregelen aanbevolen, waarmee effectievere invloed op de beloningsontwikkeling w

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10

Lalanne, Sébastien, Guillaume Bouzillé, Camille Tron, et al. "Amoxicillin-Induced Neurotoxicity: Contribution of a Healthcare Data Warehouse to the Determination of a Toxic Concentration Threshold." Antibiotics 12, no. 4 (2023): 680. http://dx.doi.org/10.3390/antibiotics12040680.

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Background: Amoxicillin (AMX)-induced neurotoxicity is well described and may be associated with AMX overexposure. No neurotoxic concentration threshold has been determined thus far. A better knowledge of maximum tolerable AMX concentrations is of importance to improve the safety of high doses of AMX. Methods: We conducted a retrospective study using the local hospital data warehouse EhOP® to generate a specific query related to AMX neurotoxicity symptomatology. All patient medical reports containing a mention of neurotoxicity clinical symptoms coupled with AMX plasma concentration measurement

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11

G.O. Al-Ani, Amina, Khansa Mohammed Younis, and Sura M.Y. Al-Taee. "Isolation and molecular identification of washing machine bacteria and study of the effect of some detergents on their growth." Bionatura 8, no. 1 (2023): 1–10. http://dx.doi.org/10.21931/rb/2023.08.01.42.

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This study aimed to isolate, molecular identify, and evaluate the antimicrobial activity of the three commercial types of household detergents; Persil (P), Arial (A), and Peros (Pe) in both forms of gel liquid and (Tate ) powder and antibiotics susceptibility test to assessed against isolates from used washing machines in Mosul city/ Iraq. A total of 46 bacterial isolates were isolated. Five isolates were designated as Kh-Am1, Kh-Am4 from the Drum part, Kh-Am3, Kh-Am6 from the Rubber door seal part and Kh-Am5 from Drain dictum; these isolates were selected for molecular identification by 16S r

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12

Atli, O., U. Demir-Ozkay, S. Ilgin, TH Aydin, EN Akbulut, and E. Sener. "Evidence for neurotoxicity associated with amoxicillin in juvenile rats." Human & Experimental Toxicology 35, no. 8 (2015): 866–76. http://dx.doi.org/10.1177/0960327115607948.

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Amoxicillin (AMX) is one of the most commonly prescribed antibiotics for children, and childhood is the period to have the highest risk for toxicity cases including drug-induced adverse reactions. Some neurological adverse effects (anxiety, hyperactivity, confusion, convulsions, and behavioral changes) have been reported related to AMX treatment. In the present study, we aimed to determine the neurotoxic effects of AMX administration at clinically relevant doses in female juvenile rats. AMX was administered in single oral daily doses of 25 and 50 mg/kg for 14 days. According to our results, wh

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13

Dinh Thi, Diu, Nguyen Phan Minh, Mai Pham Thi Ngoc, and Duc Pham Tien. "Adsorptive removal of residual amoxicillin antibiotic using cationic surfactant cetyltrimethylamonium bromide modified nanosilica rice husk." Vietnam Journal of Catalysis and Adsorption 10, no. 4 (2021): 63–67. http://dx.doi.org/10.51316/jca.2021.069.

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Amoxicillin (AMX) is a highly antibiotic resistance so that many studies focus on the removal of AMX in water environment. The present study investigated adsorptive removal of beta-lactam antibiotic AMX using a cationic surfactant, cetyltrimethylamonium bromide (CTAB) modified nanosilica (CMNS). The CTAB adsorption on nanosilica was independent of ionic strength, indicating that both electrostatic and hydrophobic interaction induced adsorption. Effective conditions for AMX removal using CMNS were systematically studied. The AMX removal using 10 mg/ mL CMNS reached 99 % at pH 9. Adsorption isot

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14

Darras-Joly, C., J. P. Bédos, C. Sauve, et al. "Synergy between amoxicillin and gentamicin in combination against a highly penicillin-resistant and -tolerant strain of Streptococcus pneumoniae in a mouse pneumonia model." Antimicrobial Agents and Chemotherapy 40, no. 9 (1996): 2147–51. http://dx.doi.org/10.1128/aac.40.9.2147.

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In vivo synergy with beta-lactam antibiotics and aminoglycosides has been studied only with penicillin-susceptible Streptococcus pneumoniae strains. We evaluated the interaction between amoxicillin (AMX) and gentamicin (GEN) on the basis of in vitro checkerboard and time-kill curves and of findings in a mouse model of acute bacteremic pneumonia due to a highly penicillin-resistant and -tolerant S. pneumoniae strain of serotype 19 (penicillin and AMX MICs of 4 micrograms/ml; gentamicin MIC of 16 micrograms/ml). Checkerboard results at 18 h of incubation showed indifference. With regard to AMX a

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15

Nobata, Shigenori, Maho Ogoshi, and Yoshio Takei. "Potent cardiovascular actions of homologous adrenomedullins in eels." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 294, no. 5 (2008): R1544—R1553. http://dx.doi.org/10.1152/ajpregu.00707.2007.

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Adrenomedullin (AM), known as a multifunctional hormone in mammals, forms a unique family of five paralogous peptides in teleost fish. To examine their cardiovascular effects using homologous AMs in eels, we isolated cDNAs encoding four eel AMs, and named AM1 (ortholog of mammalian AM), AM2, AM3 (paralog of AM2 generated only in teleost lineage), and AM5 according to the known teleost AM sequences. Unlike pufferfish, not only AM1 but AM2/3 and AM5 were expressed ubiquitously in various eel tissues. Synthetic mature AM1, AM2, and AM5 exhibited vasodepressor effects after intra-arterial injectio

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16

Vaikosen, Edebi N., Samuel J. Bunu, David Friday, and Benjamin U. Ebeshi. "Spectroscopic In-Vitro Drug-Drug Interaction Studies of Amoxicillin and Paracetamol Solid Dosage Forms." Scholars Academic Journal of Biosciences 12, no. 03 (2024): 56–64. http://dx.doi.org/10.36347/sajb.2024.v12i03.004.

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Potential drug-drug interactions (DDIs) are a public health concern in clinical therapy and drug development because of their contribution to actual adverse drug reactions (ADRs) or events. The study aimed to quantify the in-vitro drug-drug interaction of amoxicillin (AMX) and paracetamol (PCM) formulations which are commonly co-administered. Determinations were carried out by spectroscopic methods – zero-order and derivative spectroscopy. The data were analyzed using Microsoft Excel, 2016. The UV-Spectra of AMX and PCM showed two distinctive peaks at 240 nm and 260 nm were observed for AMX, w

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17

Khamayseh, Murad M., and Rana Kidak. "Thermodynamic Modeling Studies on Biosorption of Reactive Amoxicillin Antibiotic by Pithophora Macroalgae in Aqueous Solution." Nature Environment and Pollution Technology 24, no. 2 (2025): D1725. https://doi.org/10.46488/nept.2025.v24i02.d1725.

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Antibiotic removal poses a serious risk to the environment due to its intricate structure. Consequently, scientists are developing new and efficient techniques to remove antibiotic compounds from wastewater. The goal of this study is to employ green Pithophora macroalgae to remove the antibiotic amoxicillin (AMX) from a water-based solution. With a focus on understanding the process, this study assesses the application of reacting AMX biosorption on the biomass of Pithophora algae in aqueous solutions using thermodynamic modeling. The determined thermodynamic characteristics show that an endot

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18

Akhmouch, Ahmed Amin, Soukayna Hriouech, Aouatef Mzabi, et al. "Synergistic Action of AMX Associated with 1,8-Cineole and Its Effect on the ESBL Enzymatic Resistance Mechanism." Antibiotics 11, no. 8 (2022): 1002. http://dx.doi.org/10.3390/antibiotics11081002.

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The purpose of the present study is twofold. First, it aims to evaluate the synergistic action of the ß-lactam antibiotic; AMX is associated with 1,8-cineole on six clinical isolates of ESBL-producing Escherichia coli and Klebsiella pneumoniae strains. Second, it aims to determine the effect this association has on the ESBL enzymatic resistance mechanism. The synergistic action of AMX/1,8-cineole was evaluated using partial inhibitory concentrations (PIC), determined by a microplate, a checkerboard and time–kill assays. The effect of AMX/1,8-cineole associations on the ESBL enzymatic resistanc

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19

Zhang, Xiaojuan, Sisi Tian, Sara E. Beese-Sims, et al. "Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage." PLOS Genetics 17, no. 7 (2021): e1009715. http://dx.doi.org/10.1371/journal.pgen.1009715.

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Histone methylation is dynamically regulated to shape the epigenome and adjust central nuclear processes including transcription, cell cycle control and DNA repair. Lysine-specific histone demethylase 2 (LSD2) has been implicated in multiple types of human cancers. However, its functions remain poorly understood. This study investigated the histone demethylase LSD2 homolog AMX-1 in C. elegans and uncovered a potential link between H3K4me2 modulation and DNA interstrand crosslink (ICL) repair. AMX-1 is a histone demethylase and mainly localizes to embryonic cells, the mitotic gut and sheath cel

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Kim, Jeong-Won, Ji-Soo Jeong, Jin-Hwa Kim, et al. "Comparative Pharmacokinetics and Egg Residues of Amoxicillin, Single and in Combination with Bromhexine, in Laying Hens." Pathogens 13, no. 11 (2024): 982. http://dx.doi.org/10.3390/pathogens13110982.

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The need for antibiotics in commercial laying hens is increasing owing to intensive farming systems. Amoxicillin trihydrate (AMX), an aminopenicillin β-lactam antibiotic, exerts broad bactericidal activity. However, its short half-life necessitates frequent administration to ensure efficacy, thus limiting its use. Herein, we investigated the effect of concurrent administration of bromhexine hydrochloride (BRM), a mucolytic agent, on AMX pharmacokinetics, performing a comparative pharmacokinetic analysis of AMX administration alone and in combination with BRM. AMX (50 mg/kg) was administered by

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Gozlan, Igal, Adi Rotstein, and Dror Avisar. "Investigation of an amoxicillin oxidative degradation product formed under controlled environmental conditions." Environmental Chemistry 7, no. 5 (2010): 435. http://dx.doi.org/10.1071/en10037.

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Environmental context.Although amoxicillin is a widely used antibiotic, it is yet to be detected in the aquatic environment. This study traces the production of the amoxicillin-S-oxide degradation product, and shows that it is consistently obtained only under sunlight irradiation. This is the first study to demonstrate the formation, under controlled environmental conditions, of this chemically stable product of amoxicillin. Abstract.Amoxicillin (AMX) is a widely used penicillin-type antibiotic, and its presence in the environment has been widely investigated. The formation and structure of an

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Karakuş, Seçil Azime, Ayten Saraçoğlu, Eray Metin Güler, et al. "Investigation of the Effect of Amniomax on Lidocaine-Induced Toxicity in Healthy Colon Cell Culture." Biomedicines 13, no. 5 (2025): 1074. https://doi.org/10.3390/biomedicines13051074.

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Background: Lidocaine (LIDO) toxicity is a critical concern in regional anesthesia, with no specific antidote currently available. While lipid emulsions are commonly used as rescue agents in cases of local anesthetic systemic toxicity (LAST), their efficacy is inconsistent, and their safety remains controversial. AmnioMax® (AMX), a specialized cell culture medium enriched with growth factors and bioactive molecules, has the potential to offer cytoprotective effects. This study aims to investigate the therapeutic efficacy of AMX in mitigating lidocaine-induced cytotoxicity and to explore its pr

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23

Akhmouch, Ahmed Amin, Soukayna Hriouech, Hanane Chefchaou, et al. "The Combination of Amoxicillin and 1,8-Cineole Improves the Bioavailability and the Therapeutic Effect of Amoxicillin in a Rabbit Model." Antibiotics 11, no. 10 (2022): 1294. http://dx.doi.org/10.3390/antibiotics11101294.

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In this study, the effectiveness of the combination therapy of 1,8-cineole with amoxicillin (AMX) and clavulanic acid (Clav) was investigated. For this, the pharmacokinetic behaviors of AMX in rabbits were studied after a single oral dose. The animals were divided randomly into two groups: the reference group (received AMX/Clav (50/12.5 mg/kg)) and the test group (received AMX/Clav/1,8-cineole (50/12.5/10 mg/kg)). Blood samples were collected prior to administration and after T1h, T2h, T3h, and T6h post-administration. Plasma concentrations of AMX were quantified using a validated HPLC method.

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Sushmitha, Jayaprakash, and Subramanian Nellaiappan. "Electrochemical Sensing of Amoxicillin Drug-Assisted Uropathogenic E. coli Bacteria Using Gold Nanostructures—A Preliminary Study." Electrochem 4, no. 2 (2023): 291–300. http://dx.doi.org/10.3390/electrochem4020020.

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The present study focuses on the electrochemical sensing of amoxicillin (AMX, as a model antibiotic drug) and its interaction with Uropathogenic E. coli (UPEC) bacteria (as a model pathogen) under physiological conditions. The electrochemical sensor probe is formulated by nanostructured gold wires (AuNWs) embedded in a carbon nanofiber–chitosan (CNF-CHIT) matrix. The synthesis of AuNWs is characterized by scanning electron microscopy (SEM), UV-Visible spectrophotometry, and X-ray photoelectron spectroscopy (XPS). The CNF-CHIT/AuNW-modified system is characterized by SEM and XPS. Initially, the

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Garnier, Anne-Sophie, Juliette Dellamaggiore, Benoit Brilland, et al. "High Incidence of Amoxicillin-Induced Crystal Nephropathy in Patients Receiving High Dose of Intravenous Amoxicillin." Journal of Clinical Medicine 9, no. 7 (2020): 2022. http://dx.doi.org/10.3390/jcm9072022.

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Background: Amoxicillin (AMX)-induced crystal nephropathy (AICN) is considered as a rare complication of high dose intravenous (IV) AMX administration. However, recently, its incidence seems to be increasing based on French pharmacovigilance centers. Occurrence of AICN has been observed mainly with IV administration of AMX and mostly under doses over 8 g/day. Given that pharmacovigilance data are based on declaration, the real incidence of AICN may be underestimated. Thus, the primary objective of the present study was to determine the incidence of AICN in the current practice. Materials and M

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Ali, Mohammad Ashraf, and Ibrahim M. Maafa. "Photodegradation of Amoxicillin in Aqueous Systems: A Review." International Journal of Molecular Sciences 25, no. 17 (2024): 9575. http://dx.doi.org/10.3390/ijms25179575.

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Amoxicillin (AMX) is utilized in the treatment of several infectious diseases, and its concentration in wastewater has increased quite significantly over the years, posing high health hazards for humans and other living organisms. Investigations are in progress globally to eliminate AMX and other related pollutants using several methods that include adsorption, photolysis, photocatalytic degradation, photoelectrocatalytic degradation, and electrochemical conversion. AMX can be eliminated efficiently from the environment using photodegradation, either by photolysis or a photocatalytic process.

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Jeong, Ji-Soo, Jeong-Won Kim, Jin-Hwa Kim, et al. "Pharmacokinetics and Pharmacodynamics Evaluation of Amoxicillin Against Staphylococcus pseudintermedius in Dogs." Pathogens 13, no. 12 (2024): 1121. https://doi.org/10.3390/pathogens13121121.

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Antibiotic resistance in bacteria from companion animals poses significant public health risks. Prudent antibiotic use, particularly through pharmacokinetics/pharmacodynamics modeling, is crucial for minimizing resistance. We investigated the pharmacokinetics/pharmacodynamics of amoxicillin (AMX) against Staphylococcus pseudintermedius. A pharmacokinetic study was conducted on healthy dogs subcutaneously injected with a dose of 15 mg/kg AMX. The antibacterial efficacy of AMX was evaluated against a standard strain from animals (KCTC 3344) and clinical isolates from dogs (B-2, B-7, and B-8), wi

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Caballero S., Yanis E., Ceilin K. Batista C., Yerica E. González R., and Viccelda Domínguez. "Evaluación de la afectación del contaminante emergente, amoxicilina, en el crecimiento de Capsicum annum y Cajanus cajan." I+D Tecnológico 20, no. 2 (2024): 107–14. http://dx.doi.org/10.33412/idt.v20.2.4063.

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La amoxicilina (AMX) es uno de los antibióticos más consumidos a nivel de América Latina y en Panamá. Considerada contaminante emergente, cuenta con una baja tasa metabólica en humanos; entre el 80% y el 90% de la AMX se libera en el medio ambiente. La AMX se utiliza ampliamente en animales y suele mezclarse con el alimento del ganado en niveles de 250-400 mg/kg debido a su resistencia al fluido gástrico. Por lo tanto, existe el riesgo de que, a través de las rutas mencionadas anteriormente, la AMX pueda llegar al suelo, ser absorbida por los cultivos y entrar en la cadena alimentaria. Esta in

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Teresa Sponza, Delia. "Treatment of Amoxicillin Antibiotic from the Surface Water using Carboxymethyl Tragacanth Gum-Grafted-Polyaniline doped to Fe2O3 Bionanocomposites." Clinical Research and clinical Trials 7, no. 5 (2023): 01–15. http://dx.doi.org/10.31579/2693-4779/136.

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In the present study, treatment of amoxicillin (AMX) antibiotic from the surface water using carboxymethyl tragacanth gum-grafted-polyaniline doped to Fe2O3 (CMTG-g-PANI/Fe2O3) bionanocomposites (BNCs) was examined with adsorption process from pharmaceutical industry wastewater (PI ww) plant, İzmir, Turkey. Different pH values (4.0, 5.0, 7.0 and 9.0), increasing adsorption times (5 min, 10 min, 20 min and 40 min), increasing AMX concentrations (100 mg/l, 200 mg/l, 300 mg/l, 400 mg/l and 500 mg/l), increasing CMTG-g-PANI/Fe2O3 BNCs concentrations (5 mg/l, 15 mg/l, 30 mg/l and 45 mg/l), respecti

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Nguyen, Duy, and Chang-Hyun Jang. "A Label-Free Liquid Crystal Biosensor Based on Specific DNA Aptamer Probes for Sensitive Detection of Amoxicillin Antibiotic." Micromachines 12, no. 4 (2021): 370. http://dx.doi.org/10.3390/mi12040370.

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We developed a liquid crystal (LC) aptamer biosensor for the sensitive detection of amoxicillin (AMX). The AMX aptamer was immobilized onto the surface of a glass slide modified with a mixed self-assembled layer of dimethyloctadecyl [3-(trimethoxysilyl) propyl] ammonium chloride (DMOAP) and (3-aminopropyl) triethoxysilane (APTES). The long alkyl chains of DMOAP maintained the LC molecules in a homeotropic orientation and induced a dark optical appearance under a polarized light microscope (POM). In the presence of AMX, the specific binding of the aptamer and AMX molecules induced a conformatio

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Le, Thi Mai Anh, Thi My Quynh Pham, The Dung Nguyen, and Tien Duc Pham. "Adsorption characteristics of amoxicillin antibiotic on CeO2-coated SiO2 nanomaterials." Vietnam Journal of Catalysis and Adsorption 9, no. 4 (2020): 111–16. http://dx.doi.org/10.51316/jca.2020.079.

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This study investigated adsorption of beta-lactam antibiotic Amoxicillin (AMX) on a new material of cerium oxide-coated nanosilica (CeO2-coated SiO2). The CeO2-coated SiO2 based on rice husk, was characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Adsorption behaviors of AMX on CeO2-coated SiO2 at different pH and ionic strength were thoroughly studied. The highest removal of AMX using CeO2-coated SiO2 reached 99.26 % at pH 4 while the maximum adsorption capacity was found to

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Endo, Hiromi, Hideo Yoshida, Yoshiro Kohno, and Tetsuya Suga. "Effects of Clarithromycin and Amoxicillin on Gastric Emptying in Rats." Antimicrobial Agents and Chemotherapy 46, no. 10 (2002): 3331–33. http://dx.doi.org/10.1128/aac.46.10.3331-3333.2002.

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ABSTRACT The effects of oral administration of clarithromycin (CLR), amoxicillin (AMX), and lansoprazole (LPZ) on gastric emptying in rats were investigated by a glass powder method and a phenol red method. By both test methods, no significant effects on gastric emptying were observed when CLR, AMX, or LPZ was administered alone or when the three drugs were administered concomitantly. The levels of gastrointestinal absorption of [14C]CLR and [14C]AMX were measured. Four hours after injection of [14C]CLR or [14C]AMX into the stomach and duodenum loops of rats, 86.63 and 1.27% of the original am

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Abdulmajeed, Yossor R., and Noor AL-Huda Jabber Mahmood. "Production of High Surface Area Activated Carbon from Grass (Imperata)." Iraqi Journal of Chemical and Petroleum Engineering 19, no. 2 (2018): 33–37. http://dx.doi.org/10.31699/ijcpe.2018.2.6.

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In this work the production of activated carbon (AC) from Imperata is done by microwave assisted Potassium hydroxide (KOH) activation and using this activated carbon for the purpose of the uptake of amoxicillin (AMX) by adsorption process from aqueous solution. The effects for irradiation power (450-800W), irradiation time (6-12min) as well as impregnation ratio (0.5-1 g/g) on the AMX uptake and yield AMX uptake at an initial concentration of AMX (150 mg/g). The optimum conditions were 700 W irradiation power, 10 min time of irradiation, as well as 0.8 g/g impregnation ratio with 14.821% yield

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Egbedina, Abisola, and Hassan Sulaimon. "Adsorption of Frequently Used Antibiotics From Contaminated Water Using Peanut Shells." Journal of Materials & Environmental Sustainability Research 2, no. 3 (2022): 37–50. http://dx.doi.org/10.55455/jmesr.2022.008.

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The removal of pharmaceutical contaminants from water using cost-efficient and environmentally friendly adsorbents has proven to be extremely effective. The adsorption of amoxicillin (AMX) and tetracycline (TET) from wastewater using peanut shells (PS) were described in this study. The PS was characterized using Fourier Transform Infrared (FTIR) spectroscopy, Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray (EDX) techniques. The pH at the point of zero charge (pHpzc) of PS was determined to be 6.5. The influence of operating parameters such as pH, time, initial concentration, ad

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Azoulay-Dupuis, E., P. Moine, J. P. Bedos, V. Rieux, and E. Vallee. "Amoxicillin dose-effect relationship with Streptococcus pneumoniae in a mouse pneumonia model and roles of in vitro penicillin susceptibilities, autolysis, and tolerance properties of the strains." Antimicrobial Agents and Chemotherapy 40, no. 4 (1996): 941–46. http://dx.doi.org/10.1128/aac.40.4.941.

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We used a mouse model of pneumococcal pneumonia to assess the bactericidal effect of increasing doses of amoxicillin (AMX) against clinical strains with various susceptibilities to penicillin. Twelve strains that exhibited similar virulence in mice were selected. Three were penicillin susceptible (PS) (penicillin and AMX MICs = 0.01 to 0.03 microgram/ml), three were intermediately resistant (PIR) (penicillin and AMX MICs = 0.5 to 1 microgram/ml), and six were penicillin resistant (PR) (penicillin and AMX MICs = 1 to 8 micrograms/ml). Leukopenic Swiss mice were infected intratracheally with 10(

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Wodka-Gallien, Philippe. "Thomas Seignon et Merlin P. Robinson : Char AMX-30 (AMX-30B, AMX-30B2 et dérivés) ; Éditions ETAI, 2021 ; 196 pages." Revue Défense Nationale N° 843, no. 8 (2021): 203. http://dx.doi.org/10.3917/rdna.843.0203.

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Zhang, Yi-Fan, Li-Jia Liu, Feng Xu, Ming-Ying Shang, Guang-Xue Liu, and Shao-Qing Cai. "Investigation of the In Vivo Metabolism of Sibirioside A and Angoroside C in Rats by HPLC-ESI-IT-TOF-MSn." Molecules 23, no. 10 (2018): 2702. http://dx.doi.org/10.3390/molecules23102702.

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Sibirioside A and angoroside C are two important phenylpropanoid glycosides of the traditional Chinese medicine Scrophulariae Radix. High performance liquid chromatography, coupled with an ion trap time-of-flight multistage mass spectrometry equipped with electrospray ionization source (HPLC-ESI-IT-TOF-MSn), was applied to the profile and we identified the metabolites of sibirioside A and angoroside C in vivo in rats. A total of four metabolites of sibirioside A were identified: SM1, SM2 and SM3 which were known as new compounds. A total of 25 metabolites were detected for angoroside C: AM4, A

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Jellali, Salah, Wissem Hamdi, Majida Al-Harrasi, et al. "Investigations on Amoxicillin Removal from Aqueous Solutions by Novel Calcium-Rich Biochars: Adsorption Properties and Mechanisms Exploration." Processes 12, no. 8 (2024): 1552. http://dx.doi.org/10.3390/pr12081552.

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This study investigates the synthesis, characterization, and environmental application for amoxicillin (AMX) removal in batch mode of three novel calcium-rich biochars. These biochars were produced from the co-pyrolysis of poultry manure, date palm wastes, and waste marble powder at temperatures of 700 °C (Ca-B-700), 800 °C (Ca-B-800), and 900 °C (Ca-B-900). Characterization results show that increasing the pyrolysis temperature results in improved structural, textural, and surface chemistry properties. For instance, the BET surface area of the Ca-B-900 was assessed to be 52.3 m2 g−1, which is

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Ukachuku, S., D. E. Amaebi, and C. I. Dike. "Adsorption of Methyl Orange and Amoxicillin from Water using Metal-organic Framework Prepared from Solvothermal Mixing of Zn ions and 1,4-Benzenedicarboxylic Acid Moieties." Journal of Applied Sciences and Environmental Management 27, no. 2 (2023): 283–89. http://dx.doi.org/10.4314/jasem.v27i2.14.

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In this study, we determined the capacity of metal organic framework, which we prepared by the solvothermal mixing of Zn ions and 1,4-benzenedicarboxylic acid (Zn/BDC) moieties to adsorb methyl orange (MO), and amoxicillin (AMX). Results obtained show that MO and AMX adsorption capacity by Zn/BDC (mg/g) was found to increase with increase in solution concentration, for each contaminant type. Three isotherm models were applied to the adsorption data: Freundlich, Langmuir, and Temkin. R2 values obtained for the adsorption of MO, 0.9778, 0.8589 and 0.9038 for Freundlich, Langmuir and Temkin plots

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Suwondo, Kusuma Putri, Nurul Hidayat Aprilita, and Endang Tri Wahyuni. "Advanced Oxidation Processes of Amoxicillin Based on Visible Light Active Nitrogen-Doped TiO<sub>2</sub> Photocatalyst." Indonesian Journal of Chemistry 23, no. 2 (2023): 523. http://dx.doi.org/10.22146/ijc.81387.

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Environmental consequences during the COVID-19 pandemic have attracted attention due to the excessive use of antibiotics which lead to the release of the drug's residue, such as amoxicillin (AMX), into the environment. In this work, an advanced oxidation process based on a visible, active N-doped TiO2 photocatalyst was carried out to eliminate AMX. Nitrogen with different initial doping concentrations (15, 30, 45% w/w) was doped into TiO2 by the sol-gel method. The characterization technique such as XRD, FTIR, UV-SRS, and SEM-EDX revealed that nitrogen with 30% doping concentration improved th

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Bayu Aji Kuncoro and Ardiyanto Darmanto. "Teknologi RANCANG BANGUN SISTEM HIDROLIK PADA ALAT PELEPAS DAN PEMASANG RANTAI TANK AMX-13." Jurnal Otoranpur 4, Oktober (2023): 8. http://dx.doi.org/10.54317/oto.v4ioktober.364.

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Kendaraan tempur Tank AMX-13 adalah merupakan kendaraan tempur berlapis baja dan beroda rantai yang dimiliki TNI AD. Diproduksi oleh negara Prancis pada tahun 1960, Tank AMX-13 ini memiliki beberapa jenis diantaranya jenis Canon, Recovery, APC. Kendaraan Tempur Tank AMX-13 merupakan kendaraan tempur aset lama yang dimiliki oleh TNI AD yang masih digunakan sampai saat ini baik di medan tempur maupun di medan latihan. Tuntutan kesiapan operasional dan tugas pokok dari satuan Kavaleri TNI AD, pelepasan dan pemasangan rantai pada Tank AMX-13 membutuhkan perhatian. Terdapat kendala yang dihadapi ol

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Ladirat, S. E., M. H. C. Schoterman, H. Rahaoui, et al. "Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment." British Journal of Nutrition 112, no. 4 (2014): 536–46. http://dx.doi.org/10.1017/s0007114514001135.

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In the present double-blind, randomised, parallel intervention study, the effects of the intake of galacto-oligosaccharides (GOS) on the gut microbiota of twelve healthy adult subjects (aged 18–45 years with a normal BMI (18–25 kg/m2)) receiving amoxicillin (AMX) treatment were determined. All the subjects were treated with AMX (375 mg; three times per d) for 5 d and given either GOS (n 6) or placebo (maltodextrin, n 6) (2·5 g; three times per d) during and 7 d after AMX treatment. Faecal samples were collected twice before starting the treatment and on days 2, 5, 8, 12, 19 and 26. Due to AMX

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Burmańczuk, Artur, Grabowski Tomasz, Małgorzata Gbylik-Sikorska, Anna Gajda, and Cezary Kowalski. "Withdrawal of amoxicillin and penicillin G procaine from milk after intramammary administration in dairy cows with mastitis." Journal of Veterinary Research 61, no. 1 (2017): 37–43. http://dx.doi.org/10.1515/jvetres-2017-0005.

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Abstract Introduction: There are many veterinary products containing β-lactam antibiotics which are used for mastitis treatment in cows. The aim of the study was to determine whether mastitis could have any effect on amoxicillin (AMX) or penicillin G procaine (PEN) withdrawal period from milk, in the context of current maximum residue limits established by the European Commission. Material and Methods: The study was conducted on 17 dairy Black and White cows with clinical mastitis during the lactation period. The first group (n = 8) received 200 mg of amoxicillin (AMX), whereas the second grou

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Irving, Bryan. "Abstract ND03: AMX-818: Next generation conditionally active, masked T-cell engager for the treatment of HER2-expressing solid tumors." Cancer Research 82, no. 12_Supplement (2022): ND03. http://dx.doi.org/10.1158/1538-7445.am2022-nd03.

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Abstract T Cell Engagers (TCEs) are a highly potent, cancer killing modality that redirect T cell cytotoxicity against tumors that express a selected tumor-associated antigen, or TAA, bypassing the requirements for T cell recognition of tumor specific MHC/peptides. In addition to their induction of direct cytotoxicity, their potency is amplified by cytokine driven actions downstream of T cell activation that enhance the anti-tumor immune response. Because of this two-fold mechanism of action, TCEs have demonstrated clinical activity in patients with “cold” tumors that are not responsive to oth

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Kim, Da Hun, Sa-Won Lee, Jun Hak Lee, et al. "Development of Gastroretentive Floating Combination Tablets Containing Amoxicillin Trihydrate 500 mg and Levofloxacin 125 mg for Eradicating Resistant Helicobacter pylori." Pharmaceutics 16, no. 10 (2024): 1242. http://dx.doi.org/10.3390/pharmaceutics16101242.

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Background/Objectives: The aim of this work was to prepare and characterize gastroretentive floating combination tablets (GRCTs) containing 500 mg of amoxicillin trihydrate (AMX) and 125 mg of levofloxacin (LVX) that provide sustained drug release and stability at gastric pH levels for the eradication of resistant Helicobacter pylori. Method: GRCTs were prepared with low-density excipients and hydrophilic swellable polymers, including hydroxypropyl methylcellulose (HPMC) of various viscosities, polyethylene oxide (PEO), and carboxymethylcellulose (CMC), by the direct compression method. The pr

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Sedláčková, Lenka, Miroslav Průcha, Ingrid Poláková та Blanka Míková. "Evaluation of IFN-γ Enzyme-linked Immunospot Assay (ELISPOT) as a First-line Test in the Diagnosis of Non-Immediate Hypersensitivity to Amoxicillin and Penicillin". Prague Medical Report 119, № 1 (2018): 30–42. http://dx.doi.org/10.14712/23362936.2018.3.

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The current diagnostic algorithm for beta-lactam allergy is based on skin and provocation tests, both of which carry a certain risk of inducing hypersensitivity reactions. Thus, non-invasive in vitro tests reliable enough to replace skin and provocation tests at least in a portion of patients are desirable. We aimed to verify the utility of IFN-γ ELISPOT as a first-line test in patients with suspected non-immediate hypersensitivity reaction to amoxicillin (AMX) and penicillin (PNC). The prospective observational study included 24 patients with recent, suspected non-immediate hypersensitivity r

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Nishizawa, Toshihiro, Hidekazu Suzuki, Hitoshi Tsugawa, et al. "Enhancement of Amoxicillin Resistance after Unsuccessful Helicobacter pylori Eradication." Antimicrobial Agents and Chemotherapy 55, no. 6 (2011): 3012–14. http://dx.doi.org/10.1128/aac.00188-11.

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ABSTRACTA high rate of resistance (49.5 to 72.7%) to amoxicillin (AMX) was observed inHelicobacter pyloriafter two or three unsuccessful eradication attempts. Unsuccessful eradication regimens significantly increase resistance to not only clarithromycin (CLR) and metronidazole (MNZ) but also AMX.

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Marchand, Sandrine, Marylore Chenel, Isabelle Lamarche, and William Couet. "Pharmacokinetic Modeling of Free Amoxicillin Concentrations in Rat Muscle Extracellular Fluids Determined by Microdialysis." Antimicrobial Agents and Chemotherapy 49, no. 9 (2005): 3702–6. http://dx.doi.org/10.1128/aac.49.9.3702-3706.2005.

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ABSTRACT The aim of the present study was to investigate amoxicillin (AMX) distribution in muscle interstitial fluid by microdialysis in healthy, awake rats. Microdialysis probes were inserted into the jugular vein and hind leg muscle. Probe recoveries in each rat were determined by retrodialysis with cefadroxil. AMX was administered as a bolus dose of 50 mg · kg−1, and microdialysis samples were collected during 180 min. Concentrations of unbound drug in blood and muscle were analyzed simultaneously by a population approach. Simulations were conducted using a hybrid, physiologically based pha

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Soares, Geisla M. S., Flavia Teles, Jacqueline R. Starr, et al. "Effects of Azithromycin, Metronidazole, Amoxicillin, and Metronidazole plus Amoxicillin on anIn VitroPolymicrobial Subgingival Biofilm Model." Antimicrobial Agents and Chemotherapy 59, no. 5 (2015): 2791–98. http://dx.doi.org/10.1128/aac.04974-14.

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ABSTRACTChronic periodontitis is one of the most prevalent human diseases and is caused by dysbiosis of the subgingival microbiota. Treatment involves primarily mechanical disruption of subgingival biofilms and, in certain cases, adjunctive use of systemic antibiotic therapy.In vitrobiofilm models have been developed to study antimicrobial agents targeting subgingival species. However, these models accommodate a limited number of taxa, lack reproducibility, and have low throughput. We aimed to develop anin vitromultispecies biofilm model that mimics subgingival plaque, to test antimicrobial ag

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Rosa, Gisela Myrian de Lima Leite Dalla, Sandra Regina Bin Silva, Sérgio Seiji Yamada, Paulo Jorge Pereira Alves Paixão, Maiara Camotti Montanha, and Elza Kimura. "Amoxicillin dosing and pharmacokinetics in obesity for the treatment of bacterial respiratory infection secondary to COVID-19: a systematic review." Research, Society and Development 11, no. 14 (2022): e130111436040. http://dx.doi.org/10.33448/rsd-v11i14.36040.

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Objective: To conduct a systematic review of Amoxicillin (AMX) dosing and pharmacokinetics (PK) in obese subjects for the treatment of the outpatient respiratory tract infection which may be a secondary co-infection with COVID-19. Methodology: A systematic review was performed up to January 2022 on MEDLINE, EMBASE, and Web of Science. Full-text manuscripts describing AMX dosing for respiratory infection or PK in obese children, adults, and RYGB bariatric patients treated with AMX were included. Results: A total of 179 records were screened, of which 8 met the inclusion criteria. Four studies d

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