Relevant bibliographies by topics / Amyotropic Lateral Sclerosis (Lou Gehrig's Disease)

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Amyotropic Lateral Sclerosis (Lou Gehrig's Disease)'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Amyotropic Lateral Sclerosis (Lou Gehrig's Disease)"

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Ko, Hyeong Jun, and Jamyoung Yi. "The Experience of Participating in the Online Patient Community of 'Lou Gehrig’s Network': Based on the Grounded Theory." Korea Association of Yeolin Education 31, no. 5 (2023): 183–205. http://dx.doi.org/10.18230/tjye.2023.31.5.183.

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This study explores the experiences of patients and their guardians suffering from Amyotrophic Lateral Sclerosis (ALS), a rare intractable disease called Lou Gehrig's disease (ALS), by participating in an online patient community activity called 'Lou Gehrig’s Network'. To this end, after diagnosing Lou Gehrig's disease, in-depth interviews were conducted with 10 patients and their guardians participating in the 'Lou Gehrig’s Network' during the course of fighting the disease and analyzed using a grounded theory approach (Strauss & Corbin, 1998). As a result of the study, first, 54 concepts
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Sauter, W. F., G. Bush, and J. Sommerville. "A single case study: myoelectrically controlled exoskeletal mobilizer for amyotrophic lateral sclerosis (ALS) patients." Prosthetics and Orthotics International 13, no. 3 (1989): 145–48. http://dx.doi.org/10.3109/03093648909079423.

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Introduction and clinical pathology of Amyotrophic Lateral Sclerosis (ALS) Amyotrophic Lateral Sclerosis (ALS) also known as Lou Gehrig's disease is the generic name for progressive muscular atrophy and bulbar palsy. It refers to all disorders of the cortico spinal pathways which are characterized by progressive muscle weakness. After multiple sclerosis, ALS is the most common purely neurological disorder (Janiszewski et al. 1983). Information available from the ALS Society indicates that the most common age of onset is 55 years.
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Banerji, Jaya. "Reversing neglect to heal the poor: Drugs for Neglected Diseases Initiative." Biochemist 25, no. 6 (2003): 23–25. http://dx.doi.org/10.1042/bio02506023.

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In 1938, Lou Gehrig, an American baseball star, discovered he had a rare neuromuscular disease that progressively made him weaker until he was completely paralysed. He died 3 years later. Lou Gehrig's disease, also known as amyotrophic lateral sclerosis (ALS) or motor neuron disease (MND) affects one in 50000 people. Stephen Hawking has it and David Niven died from it. The causes of this fatal disease are still unknown and no cure exists, just a few drugs to relieve symptoms; however, intensive research is being carried out to find a cure. In fact, more research has been performed on this rare
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ABEL, ERNEST I. "FOOTBALL INCREASES THE RISK FOR LOU GEHRIG'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS." Perceptual and Motor Skills 104, no. 3 (2007): 1251. http://dx.doi.org/10.2466/pms.104.3.1251-1254.

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Abel, Ernest L. "Football Increases the Risk for Lou Gehrig's Disease, Amyotrophic Lateral Sclerosis." Perceptual and Motor Skills 104, no. 3_suppl (2007): 1251–54. http://dx.doi.org/10.2466/pms.104.4.1251-1254.

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DeMeo, Michele, and Johann L. Becker. "Patient and Caregiver: Q&A With Michele DeMeo And Johann Becker." Biomedical Instrumentation & Technology 47, s1 (2013): 17–19. http://dx.doi.org/10.2345/0899-8205-47.s1.17.

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With a 20-year career as hospital manager, sterilization expert, and independent consultant, Michele DeMeo continues to be a tireless advocate for the healthcare technology management (HTM) community, despite living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. In this Q&A, she and her partner and primary caregiver, Johann Becker, who happens to be a home health and hospice nurse, share insights and discuss their experience with home healthcare from the patient and caregiver perspectives.
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Vyawhare, Puja G., Gayatri M. Ahire, Neelam M. Yadav, and Dr Rupali R. Tasgaonkar. "Neurodegenerative Disorder." International Journal for Research in Applied Science and Engineering Technology 11, no. 4 (2023): 824–28. http://dx.doi.org/10.22214/ijraset.2023.50032.

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Abstract: Neurodegenerative disorders of the nervous System that Can primarily Characterized by neuron loss. Neurodegenerative diseases Such as Alzheimer, parkinson, Huntington, Amyotrophic lateral sclerosis and Multiple sclerosis are known as Lou Gehrig's disease.The huge body of evidence disorders arise by multifactorial conditions. Alzheimer's and parkinson's disease are most common neurodegenretive disorder. It includes generation of New neurons, the Phenotypic level of essential functions: Sensory & motor, and congnitive abilities. The therapeutic interventions directed toward treatem
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Sam C, Hans Elkan. "Machine Learning-Based Diagnosis and Genetic Analysis of C9ORF72-Associated Amyotrophic Lateral Sclerosis (ALS)." International Journal for Research in Applied Science and Engineering Technology 11, no. 10 (2023): 683–88. http://dx.doi.org/10.22214/ijraset.2023.56069.

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Abstract: Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease, is a devastating neurodegenerative disorder characterized by motor neuron degeneration. This research article explores the use of machine learning algorithms to diagnose ALS by analyzing mutations and insertions/deletions (indels) in the C9orf72 gene. The study utilizes a dataset to predict three stages of ALS: normal, intermediate risk, and full mutation. Three machine learning algorithms, Random Forest, SVM, and k-NN, were employed for diagnosis. Results indicate high accuracy in identifying ALS stages, wi
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Ożóg, Weronika, Martyna Borowska-Łygan, Patrycja Grzech, et al. "An Advancements In Treatment Of Amyotrophic Lateral Sclerosis (ALS)." Journal of Education, Health and Sport 82 (June 19, 2025): 60449. https://doi.org/10.12775/jehs.2025.82.60449.

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Introduction and Objective: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the loss of motor neurons. Each year, amyotrophic lateral sclerosis is diagnosed in 4-5 people per 100,000 population. The disease is commonly known as Lou-Gehrig's disease after the famous American baseball player who died two years after receiving the diagnosis at the age of 39. The etiology of the disease is not fully understood, but gene mutations that contribute to the development of ALS have been identified. Such mutations include the gene encoding superoxide dismut
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Liu, Hongyan. "Application of brain-computer interface in the treatment of amyotrophic lateral sclerosis." Theoretical and Natural Science 66, no. 1 (2024): 91–96. https://doi.org/10.54254/2753-8818/2024.18041.

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Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease and gradual freezing disease, is a rare disease. At present, it mainly relies on drug therapy and supportive therapy, but the therapeutic effect is not significant. With the progress of medical technology and computer science, brain-computer interface technology, also known as BCI, has been developed in recent years. Previous studies have shown that BCI can be used to help patients with dyskinesia recover and assist patients with brain injury to recover after operation. With further research, the central nervous system sig
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Dissertations / Theses on the topic "Amyotropic Lateral Sclerosis (Lou Gehrig's Disease)"

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Brockington, Alice R. "The role of vascular endothelial growth factor in the pathogenesis of amyotrophic lateral sclerosis : a transcriptomic approach." Thesis, University of Sheffield, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505480.

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Recent evidence suggests that the angiogenic factor, vascular endothelial growth factor (VEGF), has a role in determining the survival of motor neurones. VEGF has a pivotal function in the growth of coordinated vascular and neuronal networks in the developing embryo, and promotes the survival of neurones in vitro. Transgenic (VEGFδ/δ) mice which lack a hypoxia-responsive regulatory element in the VEGF gene express low levels of this neurotrophic factor in neural tissue, and develop adult-onset degeneration of motor neurones, which resembles amyotrophic lateral sclerosis (ALS).
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Rohilla, Kushal. "Cell-Based Models and RNA Biology for a Genetic Form of Lou Gehrig's Disease." OpenSIUC, 2020. https://opensiuc.lib.siu.edu/dissertations/1784.

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Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurological diseases. A common denominator among the majority of these disorders is the expression of expanded tandem repeat-containing RNA, referred to as xtrRNA, which can mediate molecular disease pathology in multiple ways. Frontotemporal Dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS) are two fatal neurodegenerative diseases with significant clinical, neurologic
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Wuolikainen, Anna. "Metabolomics studies of ALS a multivariate search for clues about a devastating disease /." Doctoral thesis, Umeå : Department of Pharmacology and Clinical Neuroscience, Umeå university, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-26894.

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Frakes, Ashley E. "The Role of Neuroinflammation in the Pathogenesis of Amyotrophic Lateral Sclerosis." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417649954.

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Rhoads, Timothy W. "Measuring protein metal binding via mass spectrometry : copper, zinc superoxide dismutase and amyotrophic lateral sclerosis." Thesis, 2012. http://hdl.handle.net/1957/31348.

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Amyotrophic lateral sclerosis (ALS) is a devastating disease characterized by the progressive degeneration of motor neurons. Dominantly-inherited mutations to the antioxidant enzyme Cu,Zn superoxide dismutase (SOD1) cause 3-6% of all ALS cases. The complete mechanism behind the toxicity of mutant SOD1 remains unclear, although significant evidence points to aberrant or incomplete metal-binding having a role in a toxic gain-of-function. However, the relevance of the metal-binding of SOD1 to mutant-SOD1-linked ALS remains controversial. Direct assessments of protein metal-binding from transgenic
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Books on the topic "Amyotropic Lateral Sclerosis (Lou Gehrig's Disease)"

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MacLean, Bob. It helps to talk about it: Living, not dying, with Lou Gehrig's disease. The Talk Helps ALS Research Charitable Trust, 1994.

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Robert), Ball Bob (Ball, ed. Elephants in the tea: A journey through ALS. ACTS Publishers, 2010.

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Abramovitz, Melissa. Lou Gehrigs disease. Lucent Books, 2006.

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Columbia University. Department of Neurology. Recent advances in ALS and other neuromuscular diseases: Featuring the 2nd annual Eleanor & Lou Gehrig lecture, Friday June 21, 1996. Columbia University, 1996.

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Columbia University. Department of Neurology. Advances in the diagnosis & treatment of neuromuscular disorders and ALS: Featuring the 6th annual Eleanor and Lou Gehrig lecture, Saturday, June 9, 2001 at the Neurological Institute of New York. Columbia University, 2001.

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Lou Gehrig's disease. Greenhaven Press, 2012.

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ALS: Lou Gehrig's disease: Patient advocate. Health Scouter - Equity Press, 2009.

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Donalds, Sandra L. A Beautiful Smile, a Journey with My Mother: Amyotrophic Lateral Sclerosis/ Lou Gehrig's Disease. CreateSpace, 2012.

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Bellenir, Karen. Brain Disorders Sourcebook: Basic Consumer Health Information About Strokes, Epilepsy, Amyotrophic Lateral Sclerosis (Als/Lou Gehrig's Disease) Parkinson's ... Brain Tumors (Health Reference Series). Omnigraphics, 1999.

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Judd, Sandra J. Brain Disorders Sourcebook: Basic Consumer Health Information About Strokes, Epilepsy, Amyotrophic Lateral Sclerosis (Als/Lou Gehrig's Disease) Parkinson's ... Brain Tumors (Health Reference Series). 2nd ed. Omnigraphics, 2005.

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Book chapters on the topic "Amyotropic Lateral Sclerosis (Lou Gehrig's Disease)"

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Goetz, Christopher G. "Charcot’S Disease: Amyotrophic Lateral Sclerosis." In Neurological Eponyms. Oxford University PressNew York, NY, 2000. http://dx.doi.org/10.1093/oso/9780195133660.003.0041.

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Abstract Primary amyotrophy, primary lateral sclerosis, amyotrophic lateral sclerosis (ALS), and the concept of motor neuron disease are of significant input in contemporary neurology. They have been widely discussed in the United States under the rubric “Lou Gehrig’s disease,” after the famous baseball hero who succumbed to the condition. Most commonly, ALS is referred to as Charcot’s disease, in recognition of Jean-Martin Charcot’s major nosographic contributions and his recognition of the two distinct lesions seen in the disease. These observations set the foundation for the understanding o
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"Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig’s Disease)." In The APRN and PA’s Complete Guide to Prescribing Drug Therapy. Springer Publishing Company, 2019. http://dx.doi.org/10.1891/9780826179340.0013.

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"Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig’s Disease)." In The APRN and PA’s Complete Guide to Prescribing Drug Therapy. Springer Publishing Company, 2019. http://dx.doi.org/10.1891/9780826179357.0013.

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"Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig disease)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_718.

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Wolf, Susan M. "Introduction: Gender and Feminism in Bioethics." In Feminism & Bioethics. Oxford University PressNew York, NY, 1996. http://dx.doi.org/10.1093/oso/9780195085686.003.0001.

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Abstract I was too young—I had never heard of Lou Gehrig’s disease until my grandmother Ruth returned from Minnesota with the diagnosis. Her hand already cramped and frozen, she explained that “the Mayo” predicted the rest of her would follow, in a neuromuscular degeneration called amyotrophic lateral sclerosis. I remember thinking that a trip so far from Washington, D.C., must mean they were right.
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Gamal Al-kaf, Ali, and Ali Abdullah Al-yahawi. "Current Drugs Strategies for Treatment of Rare Neurodegenerative Diseases." In Rare Neurodegenerative Disorders - New Insights [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1005438.

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Nervous system problems affect around 600 million people worldwide. Among these, neurodegenerative illnesses are often distinguished by a late adult start, a progressive clinical course, and a localized loss of neurons in the central nervous system. These include, among others, multiple sclerosis, Parkinson’s disease, amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s disease), Huntington’s disease, Prion diseases, encephalitis, epilepsy, genetic brain disorders, hydrocephalus, stroke, and Alzheimer’s and other less common dementias. The brain stem, cerebellum, thalamus, hypothalam
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Ahlskog, J. Eric. "Parkinson’s Disease: Changes in the Brain and Beyond." In The Parkinson’s Disease Treatment Book. Oxford University PressNew York, NY, 2005. http://dx.doi.org/10.1093/oso/9780195171938.003.0003.

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Abstract Parkinson’s disease (PD) is a disorder characterized by slowness, stiffness, and often tremor. It is a disorder of brain motor systems (“motor” implies movement and action). In this chapter we consider how PD fits in the larger context of all brain disorders. We will then review what is occurring inside the brain, both microscopically and biochemically, resulting in the symptoms of PD. An understanding of this is crucial, since treatment principles are based on this knowledge. A variety of disorders may damage the brain and cause it to malfunction, for example, strokes, tumors, brain
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Noble, James M. "Frontotemporal Dementia." In Navigating Life with Dementia. Oxford University PressNew York, 2022. http://dx.doi.org/10.1093/oso/9780190495688.003.0008.

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Abstract This chapter covers frontotemporal dementia, also referred to as frontotemporal lobar degeneration, which is an umbrella term used to capture several less common forms of dementia with overlapping symptoms, microscopic changes, and genetic causes. Two main forms of frontotemporal dementia exist: a behavioral form (behavioral variant) and a language form (primary progressive aphasia). Either form may be accompanied by parkinsonism or a disorder of muscle weakness called amyotrophic lateral sclerosis (also known as Lou Gehrig’s disease or motor neuron disease). Less common are forms of
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Ahlskog, J. Eric. "Background." In Dementia with Lewy Body and Parkinson's Disease Patients. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199977567.003.0005.

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This book has a combined focus on two neurodegenerative conditions: dementia with Lewy bodies and Parkinson’s disease with dementia. While patients with either disorder experience quite variable problems, these two disorders have striking similarities when viewed in the aggregate. Thus, the symptoms of these two conditions are much the same, and so are the treatment strategies. Before addressing treatment, it is crucial to define the relevant terms, broaden our understanding, and discuss how these diagnoses are made. We will start with some basics. These disorders typically start in middle age
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Conference papers on the topic "Amyotropic Lateral Sclerosis (Lou Gehrig's Disease)"

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Shah, Vrushank, Usmaan Al-Shehab, Keyur Patel, and Alexander King. "Mesenchymal Stem Cell Therapy for Amyotrophic Lateral Sclerosis." In 27th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2023. https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.148_2023.

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Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig disease, is a fatal neurodegenerative disease affecting motor neurons in the brain and spinal cord. Progressive muscle weakness, atrophy, and spasticity characterize the condition, which eventually leads to paralysis and respiratory failure. There is currently no cure for ALS, and the standard of care is supportive, with riluzole being the only approved medication that has been shown to slightly slow disease progression (1). However, the use of mesenchymal stem cells (MSCs) in the treatment of ALS is a new area of research in regene
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