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Journal articles on the topic 'Analogue methods'

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Published: 5 June 2025

Last updated: 2 August 2025

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1

Worell, Judith, and Damon Robinson. "Reinventing Analogue Methods For Research With Women." Psychology of Women Quarterly 18, no. 4 (1994): 463–76. http://dx.doi.org/10.1111/j.1471-6402.1994.tb01043.x.

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This article was prompted by the current popularity and acceptance of analogue methods in gender-related research. The use of analogues in research with women is examined here for both its strengths and limitations. We acknowledge the distinctive advantages of analogue methods in revealing the nature, extent, and potential outcomes of gender bias and stereotyping of all minority status groups. While recognizing that any method can be feminist, we address four major concerns with current applications of analogue research to questions about women and gender. These concerns cover: (a) relevance t

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2

Naveja, José J., and Martin Vogt. "Automatic Identification of Analogue Series from Large Compound Data Sets: Methods and Applications." Molecules 26, no. 17 (2021): 5291. http://dx.doi.org/10.3390/molecules26175291.

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Analogue series play a key role in drug discovery. They arise naturally in lead optimization efforts where analogues are explored based on one or a few core structures. However, it is much harder to accurately identify and extract pairs or series of analogue molecules in large compound databases with no predefined core structures. This methodological review outlines the most common and recent methodological developments to automatically identify analogue series in large libraries. Initial approaches focused on using predefined rules to extract scaffold structures, such as the popular Bemis–Mur

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Wilkins, T. A. "FREE THYROXINE ASSAYS: ANALOGUE METHODS." Lancet 326, no. 8460 (1985): 884. http://dx.doi.org/10.1016/s0140-6736(85)90143-6.

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Balos, Ljiljana, Silvija Sajic, and Vera Zdravkovic. "Elements of metabolic control in children with type 1 diabetes before and after introduction to insulin analogues." Srpski arhiv za celokupno lekarstvo 139, no. 9-10 (2011): 605–9. http://dx.doi.org/10.2298/sarh1110605b.

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Introduction. Diabetes mellitus type 1 (T1DM) in children is characterized by unstable course. A significant number of studies shows that introduction to insulin analogues treatment aims towards better control of the disease. Objective. The assessment of metabolic control in children with T1DM that were introduced to insulin analogue treatment after many years of treatment with classic (human) insulin. Methods. The study included 59 patients 2-19 years old (12.9?3.8) with T1DM, transferred from treatment with human insulin to insulin analogues treatment. Data were obtained directly from patien

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Shi, Yizhe. "Methodologies of meat analogue production and nutritional perspectives: a review." Theoretical and Natural Science 65, no. 1 (2024): 10–23. https://doi.org/10.54254/2753-8818/2024.la17931.

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With increasing global population and environmental concerns, the development of meat analogues, including plant-based proteins and cultivated meat, has become a solution for elevating global protein production and addressing sustainability issues. North America and Europe lead the meat analogue market, driven by elevated consumer awareness of health and environmental concerns. Under the influence of western diet, the Asian market is also poised for growth. While cultivated meat industry remains immature, advancements in production and cost reductions are expected to boost its market share ove

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Bebbington, Magnus W. P. "Natural product analogues: towards a blueprint for analogue-focused synthesis." Chemical Society Reviews 46, no. 16 (2017): 5059–109. http://dx.doi.org/10.1039/c6cs00842a.

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Karina Wijono, Widya, and Teti Estiasih. "The effect of lesser yam tuber flour (Dioscorea esculenta) and cooking methods on meat analogue chemical and textural properties." Advances in Food Science, Sustainable Agriculture and Agroindustrial Engineering 4, no. 2 (2021): 162–70. http://dx.doi.org/10.21776/ub.afssaae.2021.004.02.10.

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The addition of carbohydrates on gluten meat analogue has the potency to improve texture, such as lesser yam flour. It can be processed by steaming and baking. This study aimed to determine, analyze, evaluate the effect of cooking methods (steaming and baking) and substitution of lesser yam tuber flour (0%, 5%, 10%, 15%) on the texture of meat analogue and chemical properties only for the best meat analogue. This study used Randomized Block Design, Nested Design of 3 replications with 2 factors, levels of lesser yam tuber flour nested in cooking methods. The texture of meat analogue was compar

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Lam, Pun Yuet, Prudence Wing Hang Cheung, Sin Ting Lau, and Jason Pui Yin Cheung. "Quality of life of postmenopausal women with teriparatide, denosumab and alendronate: One-year prospective study with a propensity score-matched comparison." Journal of Orthopaedics, Trauma and Rehabilitation 30, no. 1 (2022): 221049172211362. http://dx.doi.org/10.1177/22104917221136282.

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Background/purpose: To evaluate and compare the effects of parathyroid hormone analogues, receptor activators of nuclear factor kappa-B ligand inhibitors and bisphosphonates on the quality of life of postmenopausal women. Methods: A prospective observational study of 23 matched postmenopausal women was conducted with propensity score analysis on quality of life at one-year follow-up. Visual analogue scale for back pain and outcome scores were carried out as the quality of life or treatment adherence measurements. Results: Teriparatide use was associated with significant improvements in visual

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Mohammad Ahmar Khan. "Advances in Traditional Electrical Validation of High-Speed Serial Connections Using Innovative Debugging Methods and Machine Learning Models." Journal of Electrical Systems 20, no. 6s (2024): 1016–23. http://dx.doi.org/10.52783/jes.2833.

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As technology continues to shrink and more heterogeneous blocks are combined into single System on a chip (SOCs), the design of high-performance integrated circuits is getting more and more difficult. In the course of silicon validation, which includes testing (Wafer Testing, Automatic Test Equipment), digital validation (Functional Data route, FSM), analogue bench validation (Electrical, Interoperability), and system validation, a number of challenges that arise from the complicated design are uncovered. The process, methods, and constraints of each domain are unique. Electrical problems that

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Laux, Wolfgang HG, Stéphane Priet, Karine Alvarez, Suzanne Peyrottes, and Christian Périgaud. "Synthesis and substrate properties towards HIV-1 reverse transcriptase of new diphosphate analogues of 9-[(2-phosphonomethoxy)ethyl]adenine." Antiviral Chemistry and Chemotherapy 26 (January 2018): 204020661875763. http://dx.doi.org/10.1177/2040206618757636.

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Background The replacement of β,γ-pyrophosphate by β,γ-phosphonate moieties within the triphosphate chain of 5′-triphosphate nucleoside analogues was previously studied for various antiviral nucleoside analogues such as AZT and 2′,3′-dideoxynucleosides. Thus, it has been shown that these chemical modifications could preserve, in some cases, the terminating substrate properties of the triphosphate analogue for HIV-RT. Herein, we aimed to study such 5′-triphosphate mimics based on the scaffold of the well-known antiviral agent 9-[(2-phosphonomethoxy)ethyl]adenine (PMEA, Adefovir). Methods Synthe

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Todorovic-Tirnanic, Mila, Vera Artiko, Smiljana Pavlovic, Dragana Sobic-Saranovic, and Vladimir Obradovic. "Contemporary nuclear medicine diagnostics of neuroendocrine tumors." Srpski arhiv za celokupno lekarstvo 143, no. 1-2 (2015): 108–15. http://dx.doi.org/10.2298/sarh1502108t.

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The new positron emission tomography (PET/CT) methods for neuroendocrine tumors detection are presented and compared with classic, conventional methods. Conventional methods use a gamma scintillation camera for patients with neuroendocrine tumor imaging, after intravenous injection of one of the following radiopharmaceuticals: 1) somatostatin analogues labeled with indium-111 (111In-pentetreotide) or technetium-99m (99mTc-EDDA/HYNIC-TOC); 2) noradrenaline analogue labeled with iodine-131 or -123 (131I/123I-MIBG); or 3) 99mTc(V)-DMSA. Contemporary methods use PET/CT equipment for patients with

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Anon., Anon. "ChemInform Abstract: Methods for Generating Oligonucleotide Analogue Libraries." ChemInform 44, no. 23 (2013): no. http://dx.doi.org/10.1002/chin.201323204.

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N’soukpoé-Kossi, C. N., A. Ahmed Ouameur, T. Thomas, T. J. Thomas, and H. A. Tajmir-Riahi. "Interaction of tRNA with antitumor polyamine analogues." Biochemistry and Cell Biology 87, no. 4 (2009): 621–30. http://dx.doi.org/10.1139/o09-036.

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We studied the interaction between tRNA and three polyamine analogues (1,11-diamino-4,8-diazaundecane·4HCl (333), 3,7,11,15-tetrazaheptadecane·4HCl (BE-333), and 3,7,11,15,19-pentazahenicosane·5HCl (BE-3333)) using FTIR, UV-visible, and CD spectroscopic methods. Spectroscopic evidence showed that polyamine analogues bound tRNA via guanine N7, adenine, uracil O2, and the backbone phosphate (PO 2– ) groups, while the most reactive sites for biogenic polyamines were guanine N7/O6, adenine N7, uracil O2, and sugar 2′-OH groups as well as the backbone phosphate group. The binding constants of polya

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Graham, Russell W. "Quaternary Mammal Communities: Relevance of the Individualistic Response and Non-Analogue Faunas." Paleontological Society Papers 11 (October 2005): 141–58. http://dx.doi.org/10.1017/s1089332600001297.

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Frequent and repeated climate fluctuations of the late Quaternary serve as a “natural experiment” for the response of species to environmental change. Analysis of the FAUNMAP database documents individualistic shifts in the geographic distributions for late Quaternary mammals. However, because the individualistic response is not necessarily random and because many species share similar niche parameters, it is possible that some species appear to form coherent groups of core species. In reality their dispersals are individualistic with regard to rate and timing. The individualistic response of

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Borowik, Piotr, Magdalena Polak-Śliwińska, Marcin Stocki, et al. "Analysis of Volatile Profile of Polish Gouda-Type Cheese and Its Analogue." Agriculture 15, no. 3 (2025): 336. https://doi.org/10.3390/agriculture15030336.

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Gouda-type cheese originated in the Netherlands, but is now produced all over the world. Analogue cheeses are cheese-like products with a lower price level that are based on non-dairy fats and proteins. The market demand for analogue cheese is currently also growing due to customers’ preference for low-fat foods. In this report, samples of Gouda-type cheese and its analogues produced by a dairy cooperative (Warmian-Masurian Voivodeship, Poland) were used as the subject of analysis; their volatile profiles were analyzed by gas chromatography coupled with mass spectrometry (GC-MS). In addition,

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Marinov, Marin. "TWO METHODS FOR 3-AMINOCYCLOPENTANESPIRO-5- HYDANTOIN THIONATION." Journal scientific and applied research 3, no. 1 (2013): 10–14. http://dx.doi.org/10.46687/jsar.v3i1.56.

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This article presents two methods for 3-aminocyclopentanespiro-5-hydantoin thionation. These methods are based on the treatment of the titled compound with P4S10 or Lawesson’s reagent. The corresponding dithio-analogue was synthesized as a result of these interactions. The structure of the product obtained was verified by 1HNMR, 13C NMR and mass spectral data.

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Martí-Clúa, Joaquín. "Methods for Inferring Cell Cycle Parameters Using Thymidine Analogues." Biology 12, no. 6 (2023): 885. http://dx.doi.org/10.3390/biology12060885.

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Tritiated thymidine autoradiography, 5-bromo-2′-deoxyuridine (BrdU) 5-chloro-2′-deoxyuridine (CldU), 5-iodo-2′-deoxyuridine (IdU), and 5-ethynyl-2′-deoxyiridine (EdU) labeling have been used for identifying the fraction of cells undergoing the S-phase of the cell cycle and to follow the fate of these cells during the embryonic, perinatal, and adult life in several species of vertebrate. In this current review, I will discuss the dosage and times of exposition to the aforementioned thymidine analogues to label most of the cells undergoing the S-phase of the cell cycle. I will also show how to i

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Horton, Pascal, Charles Obled, and Michel Jaboyedoff. "The analogue method for precipitation prediction: finding better analogue situations at a sub-daily time step." Hydrology and Earth System Sciences 21, no. 7 (2017): 3307–23. http://dx.doi.org/10.5194/hess-21-3307-2017.

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Abstract. Analogue methods (AMs) predict local weather variables (predictands) such as precipitation by means of a statistical relationship with predictors at a synoptic scale. The analogy is generally assessed on gradients of geopotential heights first to sample days with a similar atmospheric circulation. Other predictors such as moisture variables can also be added in a successive level of analogy. The search for candidate situations similar to a given target day is usually undertaken by comparing the state of the atmosphere at fixed hours of the day for both the target day and the candidat

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Sassoon, Dael, Nathalie Combourieu-Nebout, Odile Peyron, et al. "Pollen-based climatic reconstructions for the interglacial analogues of MIS 1 (MIS 19, 11, and 5) in the southwestern Mediterranean: insights from ODP Site 976." Climate of the Past 21, no. 2 (2025): 489–515. https://doi.org/10.5194/cp-21-489-2025.

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Abstract. Pleistocene interglacials, specifically Marine Isotope Stages (MISs) 19, 11, and 5, have been suggested as analogues of MIS 1 due to similar solar forcing patterns, greenhouse gas concentrations, and sea levels. There has been substantial debate regarding which of these is the most suitable analogue and so far there has been no consensus, although what really emerges from recent work is the high variation in regional climate during these periods. One of the limiting factors in our understanding of these potential analogues is the fact that very few long sequences cover the entire dur

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Girija, J., S. Kamalasundari, G. Hemalatha, and T. Umamaheswari. "Production Methodologies of Meat Analogues: A Review." Journal of Agricultural Engineering 58, no. 02 (2021): 137–48. http://dx.doi.org/10.52151/jae2021581.1741.

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Meat is a non-vegetarian food and is considered as a good source of quality nutrients. Though meat protein provide the required content of good quality protein for the body, they are also associated with higher cholesterol and fat content, which prove to be a leading cause of serious health issues. This became the primary reason for increase in a shift in demands for plant-based protein source foods. The other reason is environmental impact of animal derived products. Meat analogues are plant-based good quality protein source of food that tastes like meat protein, and texture resemble that of

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Stronge, R. L., G. B. Turner, B. T. Johnston, et al. "A rapid rise in circulating pancreastatin in response to somatostatin analogue therapy is associated with poor survival in patients with neuroendocrine tumours." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 45, no. 6 (2008): 560–66. http://dx.doi.org/10.1258/acb.2008.008033.

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Aim To assess the value of pancreastatin as a predictive factor for identifying patients with neuroendocrine tumours (NETs) who respond poorly to somatostatin analogues. Methods A retrospective study of patients with NETs. Patient records from the Northern Ireland Neuroendocrine Tumour Register were interrogated. Those who had pancreastatin concentrations measured on two or more occasions, before and during somatostatin analogue therapy (within the set time-limits) were selected. Data relating to diagnosis, surgery, somatostatin analogue therapy and survival outcome were noted. Data were subje

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Glukhikh, Igor N., and Dmitry V. Nikiforov. "Decision making for modeling of oil and gas fields by using case based reasoning." Tyumen State University Herald. Physical and Mathematical Modeling. Oil, Gas, Energy 5, no. 3 (2019): 147–63. http://dx.doi.org/10.21684/2411-7978-2019-5-3-147-163.

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This article describes a case-based reasoning (CBR) method as a decision-making tool in modeling oil and gas fields, its existing and potential application in the industry. The main direction for the application of the CBR method is the search for analogous objects for the design of oil and gas field development. The current engineering practice involves a vaguely formalized method of analogies, which does not allow defining the object as much as possible authentically the analogue that does not cause errors. The analogue object serves not only as a source of ready-made near optimal design sol

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Akinyele, O. F., A. V. Ikujenlola, and T. O. Omobuwajo. "Functional and pasting characteristics of pupuru and pupuru analogues from cassava (Manihot esculenta) and breadfruit (Artocarpus altilis) blends." Acta Universitatis Sapientiae, Alimentaria 13, no. 1 (2020): 51–68. http://dx.doi.org/10.2478/ausal-2020-0003.

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Abstract Pupuru and pupuru analogues are fermented, smoked food products usually produced from cassava or cassava substituted with a varying ratio of breadfruit. This study aims at determining and comparing the functional and pasting characteristics of pupuru and pupuru analogues with a view to expanding the utilization of breadfruit as pupuru analogue. The functional properties (water absorption capacity (%), swelling power (g/g), solubility (%)) and pasting characteristics were determined using standard methods. The results showed that the yield of the products ranged between 24.66 and 29.65

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Romantsova, Tatiana Ivanovna, T. Sh Dzhavakhishvili, and O. V. Roik. "Effects of metformin on body weight in patients with type 2 diabetes mellitus,receiving insulin analogue treatment." Diabetes mellitus 16, no. 1 (2013): 48–51. http://dx.doi.org/10.14341/2072-0351-3596.

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Aims. To study the dynamics of body weight, waist circumference, blood lipid and insulin demand in patients with type 2 diabetes mellitus (T2DM) during first year of combined treatment with metformin and insulin analogues, compared with insulin analogue monotherapy. Materials and Methods. We examined 78 patients with T2DM on newly initiated insulin therapy, including 54 females and 24 males. Median age was 56 [51.0; 64.0] years, median disease duration ? 9 [6.8;14.0] years. Participants were subdivided in two groups. First group was comprised of 48 subjects (33 females and 15 males), who recei

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Huang, Chuan Teng, Zhi Jun Wang, and Yu Jiang Zhang. "Analysis on the Analogue Slab Methods for Hollow Floor." Advanced Materials Research 838-841 (November 2013): 545–50. http://dx.doi.org/10.4028/www.scientific.net/amr.838-841.545.

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This paper presents the results of numerical analysis of hollow floor supported by the column under vertical load and horizontal load. The validity of three different analogue methods were examined and compared. The macroscopic elastic constitutive method (MEC) gave satisfactory predictions but involves an elaborate procedure for determining the equivalent elastic material parameters. The equivalent thickness approach (ETA) gave moderately higher values for the section moment than the exact values. An alternative simplified approximate method based on the effective elastic modulus (EEM) is rec

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Hotra, Les, Oksana Boyko, Ihor Helzhynskyy, Hryhorii Barylo, and Tetyana Kolach. "Methods for the Linearisation of the Transfer Function of Thermoresistive Transducers." Security of Infocommunication Systems and Internet of Things 2, no. 2 (2024): 02012. https://doi.org/10.31861/sisiot2024.2.02012.

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The article describes digital and analogue methods for linearising the conversion function of thermoresistive transducers, with a detailed analysis of analogue methods. Analogue methods for linearising bridge circuits and measurement circuits based on passing a reference current through a resistance temperature detector (RTD) are considered. Linearisation of bridge circuits is based on the formation of the compensating supply voltage of the bridge circuit, which depends on the change in the measured temperature. When using the measurement method based on passing a reference current through an

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Morales-Vicente, Fidel E., Luis A. Espinosa, Erbio Díaz-Pico, et al. "Structural Characterization of the Dimers and Selective Synthesis of the Cyclic Analogues of the Antimicrobial Peptide Cm-p5." Antibiotics 14, no. 2 (2025): 194. https://doi.org/10.3390/antibiotics14020194.

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Background/Objectives: Cm-p5 and its cyclic monomeric and dimeric analogues are known for their antifungal, antibacterial, antiviral, and antibiofilm activities. Previously, our cyclization method produced a mixture of peptides that were difficult to separate, which was then improved by a selective synthesis of the parallel dimer and its differentiation from the antiparallel by comparison of the retention times in RP-HPLC. Methods: Here, we developed a more reliable identification method for the Cm-p5 dimer identification, which included chymotrypsin proteolytic digestion and sequencing of the

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Bakanov, G. B., and S. K. Meldebekova. "On the stability of the difference analogue of the boundary value problem for a mixed type equation." BULLETIN OF THE KARAGANDA UNIVERSITY-MATHEMATICS 105, no. 1 (2022): 35–42. http://dx.doi.org/10.31489/2022m1/35-42.

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This paper considers a difference problem for a mixed-type equation, to which a problem of integral geometry for a family of curves satisfying certain regularity conditions is reduced. These problems are related to numerous applications, including interpretation problem of seismic data, problem of interpretation of Xray images, problems of computed tomography and technical diagnostics. The study of difference analogues of integral geometry problems has specific difficulties associated with the fact that for finite-difference analogues of partial derivatives, basic relations are performed with

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Третьяк, Владимир Васильевич, Антон Виталиевич Онопченко та Анастасия Сергеевна Федорова. "ВОЗМОЖНОСТИ ПРОГРАММНОГО КОМПЛЕКСА ДЛЯ ПРОЕКТИРОВАНИЯ ИМПУЛЬСНЫХ ТЕХНОЛОГИЙ МЕТОДОМ «БЛИЖАЙШЕГО СОСЕДА»". Aerospace technic and technology, № 8 (31 серпня 2019): 90–98. http://dx.doi.org/10.32620/aktt.2019.8.14.

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In aircraft and engines details are used for implementation of difficult functions: providing of bearing strength of knots and good on the whole; differentiations of different environments – working and surrounding, having different parameters on pressure, temperature, closeness, speed, providing of minimum losses at the flowline around by threads of different environments and etc Power functions in most cases execute the details of obolochkovoy form or inflexibilities flat with elements, and functions of differentiation of environments – details with the channel surfaces. The given details ca

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Makrakis, Dimitrios, Sanjay Goel, Darciann O'Sullivan, Monique White, and Benjamin Adam Gartrell. "Abiraterone with discontinuation of gonadotropin-releasing hormone (GnRH) analogues in patients (pts) with metastatic prostate cancer (PC): A single arm, phase II study." Journal of Clinical Oncology 42, no. 16_suppl (2024): 5086. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.5086.

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5086 Background: Abiraterone acetate (AA) is approved in metastatic PC. AA inhibits CYP17, required for androgen biosynthesis. A first in human trial suggested that AA monotherapy was inadequate to maintain castrate testosterone (T) in non-castrate men and AA development required continued GnRH analogues. However, T recovery is often delayed post GnRH analogue cessation; the need for their ongoing use to maintain castrate T with AA use is unclear and studies are limited. We present a single arm, phase II trial of pts with metastatic PC treated with AA+Prednisone (AAP) after GnRH discontinuatio

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Murray, Alan F., and Robin Woodburn. "The Prospects for Analogue Neural VLSI." International Journal of Neural Systems 08, no. 05n06 (1997): 559–79. http://dx.doi.org/10.1142/s0129065797000525.

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In recent years, the efforts of analogue, neural-hardware designers have shifted from generic analogue neurocomputers to "niche" markets in sensor fusion and robotics, and we explain why this is so. We describe the main differences between digital and analogue computation, and consider the advantages of pure analogue and pulsed methods of design. We then investigate some important issues in analogue design of neural machines, namely weight storage (volatile and non-volatile), on-chip learning, and arithmetic accuracy and its relationship to noise. Finally, we outline those areas in which analo

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MURRAY, ALAN. "ANALOGUE VLSI FOR PROBABILISTIC NETWORKS AND SPIKE-TIME COMPUTATION." International Journal of Neural Systems 11, no. 01 (2001): 23–32. http://dx.doi.org/10.1142/s0129065701000473.

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The history and some of the methods of analogue neural VLSI are described. The strengths of analogue techniques are described, along with residual problems to be solved. The nature of hardware-friendly and hardware-appropriate algorithms is reviewed and suggestions are offered as to where analogue neural VLSI's future lies.

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El Ameen, Ammar, Guillaume Vandermeer, Raoul K. Khanna, and Pierre-Jean Pisella. "Objective ocular surface tolerance in patients with glaucoma treated with topical preserved or unpreserved prostaglandin analogues." European Journal of Ophthalmology 29, no. 6 (2018): 645–53. http://dx.doi.org/10.1177/1120672118805877.

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Purpose: Preservatives in glaucoma medications have been associated with ocular toxicity. We compared ocular signs and symptoms in patients with open-angle glaucoma or ocular hypertension treated in monotherapy with preserved or preservative-free prostaglandin analogues. Methods: Observational cross-sectional clinical study in real life. 82 patients treated for at least 6 months with prostaglandin analogue were assessed for intraocular pressure, ocular symptoms and ocular signs including conjunctival hyperaemia, tear break-up time and tear meniscus height measured using objective and non-invas

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Inujima, Hiroshi, and Uichi Kichijima. "Degradation Detection Methods for Analogue ICs Using in Real Plants." IEEJ Transactions on Electronics, Information and Systems 109, no. 12 (1989): 862–68. http://dx.doi.org/10.1541/ieejeiss1987.109.12_862.

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Clarke, R. W., M. P. J. Yardley, C. M. Davies, A. Panarese, R. T. Clegg, and A. J. Parker. "Palatoplasty for Snoring: A Randomized Controlled Trial of Three Surgical Methods." Otolaryngology–Head and Neck Surgery 119, no. 3 (1998): 288–92. http://dx.doi.org/10.1016/s0194-5998(98)70064-6.

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In a randomized, controlled trial, 62 patients (47 men and 15 women) with severe antisocial snoring, but no sleep apnea, were allocated to one of three surgical treatments. These were uvulopalato-pharyngoplasty, laser palatoplasty, and diathermy palatoplasty. Postoperative morbidity was measured on a visual analogue scale of severity of pain, dysphagia, and nasal regurgitation at 1, 2, and 7 days after the operation. Efficacy of each procedure was measured by asking the sleeping partner to record the severity of snoring before and after the operation, again on a visual analogue scale. Measurem

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Edwards, Mark, and Sowjanya Ratho. "Synthesis of p-Chlorocelecoxib from 4-Methylacetophenone & its Spectral Characterization." Indo Global Journal of Pharmaceutical Sciences 02, no. 03 (2012): 239–44. http://dx.doi.org/10.35652/igjps.2012.29.

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Celecoxib is a non-steroidal anti-inflammatory drug used in the treatment of pain and inflammation. The objective of this study is to synthesize p-chlorocelecoxib by the condensation of 4-methylacetophenone and ethyl trifluoroacetate, followed by reaction with 4-(2-chlorohydrazinly)benzenesulfanimide & identification of celecoxib analogue through several analytical methods like UV visible, IR, TLC, NMR etc. The methods used have been found to be fast, efficient, reproducible and suitable for the identification of celecoxib analogues. The purified β-keto-diester reaction with 4-chlorophenyl

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Garrett, C., L. Maikowski, and R. Thomas. "Automating the Diagnosis of Analogue Circuits — A Tutorial." International Journal of Electrical Engineering & Education 33, no. 3 (1996): 225–38. http://dx.doi.org/10.1177/002072099603300304.

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Automating the diagnosis of analogue circuits–a tutorial A tutorial study of automatic analogue fault diagnosis is presented. Major issues, namely observability, controllability and deduction are explained but then issues of tolerance and fault models peculiar to diagnosis of faults in analogue systems are discussed. A taxonomy of methods is followed by examples and 25 references.

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Dahikar, Girish D., and Rajendra O. Ganjiwale. "Synthesis, Spectral Characterization, in silico Molecular Docking and Pharmacological Screening of Some Quinazoline Analogues as Anticonvulsants." Asian Journal of Chemistry 37, no. 6 (2025): 1415–20. https://doi.org/10.14233/ajchem.2025.33816.

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A new analogues of 2-methyl-3-(6-substituted-benzothiazol-2-yl)-3H-quinazolin-4-one [Dm1-Dm5] and their 6-bromo analogues [Dm6-Dm10], similarly a new analogues of 2-methyl-3-(pyridin-4-yl-formamide)-3H-quinazolin-4-one [Em1] and its 6-bromo analogue [Em2] were synthesized and characterized by melting point, elemental and spectral [FTIR, (1H and 13C) NMR and MS] methods. The anticonvulsant activity of selected analogues was assessed against maximal electroshock (MES) induced convulsions model in albino mice. The selected analogues were injected intraperitoneally at dose 20 mg/kg body weight and

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Ryoo, Cheon. "Symmetric Identities for (P,Q)-Analogue of Tangent Zeta Function." Symmetry 10, no. 9 (2018): 395. http://dx.doi.org/10.3390/sym10090395.

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The goal of this paper is to define the ( p , q ) -analogue of tangent numbers and polynomials by generalizing the tangent numbers and polynomials and Carlitz-type q-tangent numbers and polynomials. We get some explicit formulas and properties in conjunction with ( p , q ) -analogue of tangent numbers and polynomials. We give some new symmetric identities for ( p , q ) -analogue of tangent polynomials by using ( p , q ) -tangent zeta function. Finally, we investigate the distribution and symmetry of the zero of ( p , q ) -analogue of tangent polynomials with numerical methods.

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Sushinina, L. P., A. P. Smirnova, S. V. Ustinkina, et al. "Synthesis and investigation of modified gastrin fragments." Russian Journal of Biotherapy 16, no. 3 (2017): 63–68. http://dx.doi.org/10.17650/1726-9784-2017-16-3-63-68.

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Background. The purpose of this investigation is the search of new compounds with high selectivity of antitumor action on the tumor of the gastrointestinal tract (GIT) in the series of analogues of the peptide hormone gastrin. Objective: synthesis of 2 analogues of gastrin, 1 of which contains the cytotoxic group, the study of their cytotoxic and antitumor activity. Materials and methods. Synthesis of peptides was carried out by classical methods of peptide chemistry. Cytotoxic activity was studied on the cell culture НСТ116. Antitumor activity of analogues of gastrin were studied on transplan

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Kazimierczuk, Z., R. Stolarski та D. Shugar. "Stereospecific Synthesis by the Sodium Salt Glycosylation Method of Halogeno Benzimidazole 2′ -Deoxyribose Analogues of the Inhibitor of hnRNA Synthesis, 5,6-Dichloro-1-(β-ᴅ-ribofuranosyl)benzimidazole (DRB)". Zeitschrift für Naturforschung C 40, № 9-10 (1985): 715–20. http://dx.doi.org/10.1515/znc-1985-9-1023.

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Abstract The recently developed stereospecific sodium salt glycosylation procedure has been successfully applied to the synthesis of the β-ᴅ-2′-deoxyribofuranosides of benzimidazole, 5,6-dihalogeno benzimidazoles, and some 2-substituted analogues in high yield. The 5,6-dibromo analogue was obtained by bromination of the parent nucleoside. These have all been characterized by spectroscopic methods, including 1H NMR, which permitted analyses of their solution conformations and comparison with those of the corresponding ribofuranosides. Some biological aspects, including preliminary results on c

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Ilias, Ioannis, Anju Sahdev, Rodney H. Reznek, Ashley B. Grossman, and Karel Pacak. "The optimal imaging of adrenal tumours: a comparison of different methods." Endocrine-Related Cancer 14, no. 3 (2007): 587–99. http://dx.doi.org/10.1677/erc-07-0045.

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Computed tomography (CT; unenhanced, followed by contrast-enhanced examinations) is the cornerstone of imaging of adrenal tumours. Attenuation values of <10 Hounsfield units on an unenhanced CT are practically diagnostic for adenomas. When lesions cannot be characterised adequately with CT, magnetic resonance imaging (MRI) evaluation (with T1- and T2-weighted sequences and chemical shift and fat-suppression refinements) is sought. Functional nuclear medicine imaging is useful for adrenal lesions that are not adequately characterised with CT and MRI. Scintigraphy with [131I]-6-iodomethyl nor

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Waxman, J. H., J. Sandow, P. Abel, et al. "Two-monthly depot gonadotropin releasing hormone agonist (buserelin) for treatment of prostatic cancer." Acta Endocrinologica 120, no. 3 (1989): 315–18. http://dx.doi.org/10.1530/acta.0.1200315.

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Abstract. The agonist analogues of gonadotropin-releasing hormone provide an alternate medical therapy for prostatic cancer. Current methods of administration of these analogues by daily injection or nasal spray is suboptimal in an elderly population. We have performed a pharmacological and endocrine evaluation of a new depot preparation of one such analogue, buserelin, active for 2 months. Thirty patients with advanced symptomatic prostatic cancer were treated. Serum testosterone was suppressed for the duration of treatment which ranged up to 14 months. The release characteristics of the depo

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Becker, Stephan, Hieu T. Nguyen, Sofie Nollet, Tomas M. Fernandez-Steeger, Dennis Laux, and Christoph Hilgers. "Methods to analyse fracture orientation patterns in a Lower Carboniferous carbonate reservoir analogue in the Voreifel, Germany." Zeitschrift der Deutschen Gesellschaft für Geowissenschaften 165, no. 3 (2014): 319–30. http://dx.doi.org/10.1127/1860-1804/2014/0078.

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Cheng, Jinhua. "On Some Multipliers Related to Discrete Fractional Integrals." Mathematics 12, no. 10 (2024): 1545. http://dx.doi.org/10.3390/math12101545.

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This paper explores the properties of multipliers associated with discrete analogues of fractional integrals, revealing intriguing connections with Dirichlet characters, Euler’s identity, and Dedekind zeta functions of quadratic imaginary fields. Employing Fourier transform techniques, the Hardy–Littlewood circle method, and a discrete analogue of the Stein–Weiss inequality on product space through implication methods, we establish ℓp→ℓq bounds for these operators. Our results contribute to a deeper understanding of the intricate relationship between number theory and harmonic analysis in disc

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Jarløv, Anders, and Tim Toftgaard Jensen. "Model Simulating the Heat Transfer of Skin." International Journal of Biomedical and Clinical Engineering 3, no. 2 (2014): 42–58. http://dx.doi.org/10.4018/ijbce.2014070104.

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The relationship between surface temperature and heat transfer in a section of isotropic material with plane parallel sides, in this context simulating human skin, can be attained by means of analogue models. A model, in the form of electric circuits, enables the analogue functions to be recorded as electrical signals. Analogue heat transfer rates derived by processing voltage data from the models can be used for the determination of analogue measures of blood perfusion of the skin, which is generally stated in terms of ml blood flow per 100 ml tissue per minute. Analogue time scales can be co

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Stanojlovic, Olivera, Dragan Hrncic, Drenka Turjacanin, Dragana Zivanovic, and Veselinka Susic. "Delta sleep-inducing peptide and its analogues alleviate the severity of metaphit-induced audiogenic seizures in rats." Medical review 60, no. 9-10 (2007): 436–40. http://dx.doi.org/10.2298/mpns0710436s.

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Introduction. We investigated the potential of delta sleep-inducing peptide (DSIP) and its analogue DSIP-12 (a nonapeptide with alanine in position 2 of DISP molecule substituted by beta-alanine) and tetrapeptide analogue DSIP1-4, to antagonize metaphit- (1-1(3-isothiocyanatophenyl)-cyclohexyl piperidine) induced generalized reflex audiogenic seizures in adult male Wistar albino rats. Material and Methods. Five groups of adult male Wistar rats were intraperitoneally treated with: 1. saline; 2. metaphit; 3. metaphit + DSIP; 4. metaphit + DSIP1-4 and 5. metaphit + DSIP-12. To examine the blockin

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Zheng, Shengjie, Guiju Duan, and Baizhan Xia. "Progress in Topological Mechanics." Applied Sciences 12, no. 4 (2022): 1987. http://dx.doi.org/10.3390/app12041987.

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Topological mechanics is rapidly emerging as an attractive field of research where mechanical waveguides can be designed and controlled via topological methods. With the development of topological phases of matter, recent advances have shown that topological states have been realized in the elastic media exploiting analogue quantum Hall effect, analogue quantum spin Hall effect, analogue quantum valley Hall effect, higher-order topological physics, topological pump, topological lattice defects and so on. This review aims to introduce the experimental and theoretical achievements with defect-im

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Suchorolski, Piotr, Adam Smolarczyk, Piotr Łukaszewski, et al. "Comparative Analysis of Analogue and Digital Methods for Magnetic Flux Estimation in the Core of a Medium-Voltage Voltage Transformer Operating Under Ferroresonance Conditions." Applied Sciences 14, no. 23 (2024): 11304. https://doi.org/10.3390/app142311304.

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The main objective of the research described in the article was to determine the following: Is it possible to estimate the magnetic flux linkage in the core of a voltage transformer using analogue or digital methods? Will it be possible to estimate it approximately both in the normal state and in the state of deep core saturation (ferroresonant state)? The research aimed to identify the advantages and disadvantages of both proposed estimation methods. As part of the research described in this paper, a simulation model was developed and executed in the MATLAB/Simulink environment to generate a

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Schreuders, Floor K. G., Miek Schlangen, Konstantina Kyriakopoulou, Remko M. Boom, and Atze Jan van der Goot. "Texture methods for evaluating meat and meat analogue structures: A review." Food Control 127 (September 2021): 108103. http://dx.doi.org/10.1016/j.foodcont.2021.108103.

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