Relevant bibliographies by topics / Analogues de l'hydroxy-9 ellipticine

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Academic literature on the topic 'Analogues de l'hydroxy-9 ellipticine'

Author: Grafiati
Published: 4 June 2021
Last updated: 16 February 2022

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Journal articles on the topic "Analogues de l'hydroxy-9 ellipticine"

1

ANDERSON, W. K., A. GOPALSAMY, and P. S. REDDY. "ChemInform Abstract: Design, Synthesis, and Study of 9-Substituted Ellipticine and 2- Methylellipticinium Analogues as Potential CNS-Selective Antitumor Agents." ChemInform 25, no. 50 (2010): no. http://dx.doi.org/10.1002/chin.199450157.

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Sharples, Derek, György Hajós, Zsuzsanna Riedl, Dorottya Csányi, József Molnár, and Diana Szabó. "Ellipticine analogues and related compounds as inhibitors of reverse transcriptase and as inhibitors of the efflux pump." Archiv der Pharmazie 334, no. 8-9 (2001): 269. http://dx.doi.org/10.1002/1521-4184(200109)334:8/9<269::aid-ardp269>3.0.co;2-#.

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GRIBBLE, G. W., M. G. SAULNIER, J. A. OBAZA-NUTAITIS, and D. M. KETCHA. "ChemInform Abstract: A Versatile and Efficient Construction of the 6H-Pyrido(4,3-b) carbazole Ring System. Syntheses of the Antitumor Alkaloids Ellipticine, 9-Methoxyellipticine, and Olivacine and Their Analogues." ChemInform 24, no. 9 (2010): no. http://dx.doi.org/10.1002/chin.199309242.

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4

Márquez, Edgar, José R. Mora, Virginia Flores-Morales, Daniel Insuasty, and Luis Calle. "Modeling the Antileukemia Activity of Ellipticine-Related Compounds: QSAR and Molecular Docking Study." Molecules 25, no. 1 (2019): 24. http://dx.doi.org/10.3390/molecules25010024.

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The antileukemia cancer activity of organic compounds analogous to ellipticine representes a critical endpoint in the understanding of this dramatic disease. A molecular modeling simulation on a dataset of 23 compounds, all of which comply with Lipinski’s rules and have a structure analogous to ellipticine, was performed using the quantitative structure activity relationship (QSAR) technique, followed by a detailed docking study on three different proteins significantly involved in this disease (PDB IDs: SYK, PI3K and BTK). As a result, a model with only four descriptors (HOMO, softness, AC1RA
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Bisagni, Emile, and Nguyen Chi Hung. "Premiere synthese de methyl-4-5h- pyrido ¦3',4':4,5¦pyrrolo ¦3,2-c¦pyridines, analogues tricycliques des aza-9 ellipticines." Tetrahedron 42, no. 8 (1986): 2311–18. http://dx.doi.org/10.1016/s0040-4020(01)90611-8.

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Skarin, Tobias, Barbro Lundh Rozell, Jan Bergman, Rune Toftgård, and Lennart Möller. "Protection against 12-O-tetradecanoylphorbol-13-acetate induced skin-hyperplasia and tumor promotion, in a two-stage carcinogenesis mouse model, by the 2,3-dimethyl-6(2-dimethylaminoethyl)-6H-indolo-[2,3-b]quinoxaline analogue of ellipticine." Chemico-Biological Interactions 122, no. 2 (1999): 89–106. http://dx.doi.org/10.1016/s0009-2797(99)00117-9.

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7

BISAGNI, E., and NGUYEN CHI HUNG NGUYEN CHI HUNG. "ChemInform Abstract: A First Synthesis of 4-Methyl-5H-Pyrido[3′,4′ :4,5]pyrrolo[3,3-c]pyridines, Tricyclic Analogues of 9-Aza Ellipticines." Chemischer Informationsdienst 17, no. 33 (1986). http://dx.doi.org/10.1002/chin.198633196.

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Dissertations / Theses on the topic "Analogues de l'hydroxy-9 ellipticine"

1

Castin, Isabelle. "Synthèse d'analogues de l'hydroxy-9 ellipticine : réactivité dans des conditions oxydatives." Paris 11, 1988. http://www.theses.fr/1988PA112176.

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Les travaux relatés dans ce mémoire s'inscrivent dans le cadre d'une meilleure compréhension du mode d'action de l'acétate dhydroxy-9 N Méthyl -2 ellipticinium, dérivé de l'ellipticine, et de l'évaluation de l'activité cytotoxique de certain de ses analogues. Ce travail est présenté en trois parties :La première partie décrit la réactivité régiospécifique du groupement hydroxy-5 indole de l'hydroxy-9 ellipticine dans des conditions oxydatives. Cette réactivité est illustrée à l'aide du diméthyle-Piyle-1 ,4 hydroxy-6 carbazole qui, dans sa forme au quinonelmine, peut conduire à des additions de
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2

Castin, Isabelle. "Synthèse d'analogues de l'hydroxy-9 ellipticine réactivité dans des conditions oxydatives /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376125202.

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3

Chi, Hung Nguyen. "Synthèse et étude de nouveaux analogues tetracycliques et tricycliques des ellipticines et aza-9 ellipticines." Paris 11, 1985. http://www.theses.fr/1985PA112290.

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La présente thèse concerne la synthèse de nouveaux analogues tétracycliques et tricycliques des Ellipticines et aza-9 Ellipticines, ainsi que l'étude de L'étude de leurs propriétés biologiques. L’étude de la lithiation des furo-et pyrrolo [3,2-c] pyridines présentée dans le premier chapitre montre que l'échange avec le ter. Butyl lithium s'effectue sur le sommet 2 de ces hétérocycles. Cela permet d'accéder à divers dérivés fonctionnalisés sur leur sommet 2 à partir desquels nous avons pu accéder d'une part à des pyrido [4,3-b] benzo [f] indoles et d'autre part à des pyrido [3',4': 4,5] pyrrolo
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