Academic literature on the topic 'Anatomy, Pathological'

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Journal articles on the topic "Anatomy, Pathological"

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Loshchilov, Yu A. "Pathological anatomy of pneumoconiosis." PULMONOLOGIYA, no. 2 (April 28, 2007): 117–19. http://dx.doi.org/10.18093/0869-0189-2007-0-2-117-119.

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Gruzdeva, O. S. "PATHOLOGICAL ANATOMY OF FROSTBITE." Transbaikalian Medical Bulletin, no. 4 (2020): 137–44. http://dx.doi.org/10.52485/19986173_2020_4_137.

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MORISON, J. EDGAR. "Pathological Anatomy of Anoxia." Developmental Medicine & Child Neurology 3, no. 6 (November 12, 2008): 559–66. http://dx.doi.org/10.1111/j.1469-8749.1961.tb10421.x.

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Müller, K. M. "Pulmonary Metastases. Pathological Anatomy." Thoracic and Cardiovascular Surgeon 34, S 2 (November 1986): 115–19. http://dx.doi.org/10.1055/s-2007-1022187.

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Müller, K. M., and M. Respondek. "Pulmonary metastases: Pathological anatomy." Lung 168, S1 (December 1990): 1137–44. http://dx.doi.org/10.1007/bf02718254.

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Orlinskaya, N. Yu, and A. B. Elkanova. "Pathological anatomy of thyrotoxic liver." Medical alphabet, no. 17 (September 23, 2020): 36–38. http://dx.doi.org/10.33667/2078-5631-2020-17-36-38.

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The work was performed on experimental material. An experimental model of thyrotoxicosis in laboratory animals, white male rats, was obtained by daily administration оf l-thyroxine at a dose of 1.6 mg per 1 kg of body weight. The duration of the experiment was 45 days. 67 mature rats weighing 250–300 g were selected for the experiment. Rats were removed from the experiment after 7, 14, 21, 28, 35 and 45 days. As a control, we used 22 rats that were not injected with L-thyroxine. The level of thyroid hormones in the blood of rats was determined by enzyme immunoassay. A macroscopic study was performed and the size and mass of the rat liver were determined. For histological examination, pieces of liver tissue were taken, and they were fixed in 10 % buffered formalin for 10 days. Histological preparations were prepared by the standard method, using histological, histochemical and immunohistochemical studies. The results of the study showed that in experimental thyrotoxicosis, the level of thyroid hormones increases: T3 (triiodothyronine) equals 21.37 ± 0.03 mmol/l, 4.75 ± 0.02 mmol/l in the control; T4 (thyroxine) equals 2.55 ± 0.03 mmol/l, 1.80 ± 0.03 mmol/l in the control. Macroscopic examination revealed a 2-fold increase in the size and weight of the liver. Histological examination revealed widespread interstitial edema of the liver stroma, dystrophic and destructive changes, necrosis of hepatocytes, formation of cavities, thinning and atrophy of the liver beams, lymphocytic infiltration. The immunohistochemical study shows a decrease in Ki-67 expression level to 1.8 % compared to the control (5.0 %), which indicates a decrease in reparative processes in the liver.
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Mello, Evandro Sobroza de, and Venâncio Avancini Ferreira Alves. "Chronic hepatitis C: pathological anatomy." Brazilian Journal of Infectious Diseases 11 (October 2007): 28–32. http://dx.doi.org/10.1590/s1413-86702007000700010.

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Krismann, Michael, Klaus-Michael Müller, Malgorzata Jaworska, and Georg Johnen. "Pathological anatomy and molecular pathology." Lung Cancer 45 (August 2004): S29—S33. http://dx.doi.org/10.1016/j.lungcan.2004.04.005.

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Leo, Laura Anna, Vera Lucia Paiocchi, Susanne Anna Schlossbauer, Elisa Gherbesi, and Francesco F. Faletra. "Anatomy of Mitral Valve Complex as Revealed by Non-Invasive Imaging: Pathological, Surgical and Interventional Implications." Journal of Cardiovascular Development and Disease 7, no. 4 (November 4, 2020): 49. http://dx.doi.org/10.3390/jcdd7040049.

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Knowledge of mitral valve (MV) anatomy has been accrued from anatomic specimens derived by cadavers, or from direct inspection during open heart surgery. However, today two-dimensional and three-dimensional transthoracic (2D/3D TTE) and transesophageal echocardiography (2D/3D TEE), computed tomography (CT) and cardiac magnetic resonance (CMR) provide images of the beating heart of unprecedented quality in both two and three-dimensional format. Indeed, over the last few years these non-invasive imaging techniques have been used for describing dynamic cardiac anatomy. Differently from the “dead” anatomy of anatomic specimens and the “static” anatomy observed during surgery, they have the unique ability of showing “dynamic” images from beating hearts. The “dynamic” anatomy gives us a better awareness, as any single anatomic arrangement corresponds perfectly to a specific function. Understanding normal anatomical aspects of MV apparatus is of a paramount importance for a correct interpretation of the wide spectrum of patho-morphological MV diseases. This review illustrates the anatomy of MV as revealed by non-invasive imaging describing physiological, pathological, surgical and interventional implications related to specific anatomical features of the MV complex.
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Paukov, V. S., and Yu A. Erokhin. "The pathological anatomy of alcoholic disease." Almanac of Clinical Medicine 48, no. 2 (July 30, 2020): 84–93. http://dx.doi.org/10.18786/2072-0505-2020-48-015.

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Dissertations / Theses on the topic "Anatomy, Pathological"

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Романюк, Анатолій Миколайович, Анатолий Николаевич Романюк, Anatolii Mykolaiovych Romaniuk, Роман Андрійович Москаленко, Роман Андреевич Москаленко, Roman Andriiovych Moskalenko, А. В. Доценко, В. І. Мороз, and Ю. П. Кришталь. "Історія розвитку патологоанатомічної служби на Сумщині." Thesis, Видавництво СумДУ, 2009. http://essuir.sumdu.edu.ua/handle/123456789/6678.

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Романюк, Анатолій Миколайович, Анатолий Николаевич Романюк, Anatolii Mykolaiovych Romaniuk, Ганна Юріївна Будко, Анна Юрьевна Будко, Hanna Yuriivna Budko, Роман Андрійович Москаленко, et al. "Клініко-анатомічні аспекти у підготовці лікаря-інтерна зі спеціальності "Патологічна анатомія"." Thesis, Видавництво СумДУ, 2010. http://essuir.sumdu.edu.ua/handle/123456789/4801.

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Morris, Melinda. "Clinical and pathological predictors of survival for stage II and III colon cancer patients treated with or without chemotherapy : a population-based study." University of Western Australia. School of Surgery and Pathology, 2007. http://theses.library.uwa.edu.au/adt-WU2008.0012.

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[Truncated abstract] Clinical and pathological predictors of survival for stage II and III colon cancer patients treated with or without chemotherapy: a population-based study. Aim: Using a population-based cohort of colorectal cancer (CRC), the major aims of this study were to: 1. Identify clinico-pathological markers that can be used to define a subset of stage II colon cancer patients with excellent prognosis and who therefore do not require referral for adjuvant chemotherapy; 2. Investigate whether there is a survival benefit from the use of adjuvant chemotherapy in a population-based cohort of stage II colon cancer; 3. Investigate stage III colon cancer patients for evidence of predictive markers for response to 5FU chemotherapy; 4. Investigate CRC for age-related differences in clinico-pathological and molecular features. Hypotheses to be tested: 1. A subset of good prognosis stage II colon cancers can be defined using routine pathological markers; 2. Females colon cancer patients gain more survival advantage from 5FU chemotherapy than males; 3. Tumours from young CRC patients have different molecular characteristics to those from older patients; 4. The underlying molecular characteristics of tumour can impact upon the response to 5FU chemotherapy. Methods: The study cohort consisted of 5,971 cases diagnosed between 1993 and 2003 representing over 90% of the CRCs diagnosed in the state of Western Australia. Results: The major findings of this translational research into colon cancer can be summarized as follows: The morphological features of serosal and vascular invasion allow for prognostic stratification of stage II colon cancer into
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Chen, Dan Chary. "Pathological image processing and geometric modelling for improved management of colorectal cancer." Thesis, University of Oxford, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711813.

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Orendurff, Michael S. "Dynamic foot and ankle characteristics in functionally relevant gait performance in those with and without a pathology." Thesis, University of Roehampton, 2012. https://pure.roehampton.ac.uk/portal/en/studentthesis/dynamic-foot-and-ankle-characteristics-in-functionally-relevant-gait-performance-in-those-with-and-without-a-pathology(abd2dc9a-26a9-47fd-afcc-edee49360c64).html.

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The human ankle joint is hypothesized to be a primary controller of support, propulsion and steering during locomotion. A series of experiments were initiated to understand ankle plantarflexor muscle kinematics and kinetics in normal and pathological gait, and to define the specific locomotor demands of community ambulation. Additional experiments were then conducted to quantify the effects of walking speed on plantar pressures and centre of mass motion, to illuminate the role of the ankle in acceleration and deceleration during walking, and to examine how humans alter their kinematics and kinetics to turn. The results of these experiments provide support for the hypothesis that the ankle joint is important in a wide range of locomotor movements beyond walking straight ahead at constant speed. The ankle appears instrumental in adapting to different walking speeds, altering both the pressures on specific regions the plantar surface and the motion of the centre of mass across a range of speeds. The ankle also has subtle kinetic changes that appear to modulate acceleration and deceleration during single limb stance. For turning, the ankle plays a role during slowing into the turn and accelerating after the turn, but mediolateral shears appear to alter the trajectory of the body to negotiate a corner and the external hip rotators appear to rotate the trunk toward the new direction of travel. This work extends our understanding of the ankle in functionally relevant gait activities beyond simple straight-ahead walking at constant speed. The published papers included in this supporting statement have been cited by 180 different subsequent peerreviewed publications, suggesting that this work has had some impact on the field.
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Кузенко, Євген Вікторович, Евгений Викторович Кузенко, Yevhen Viktorovych Kuzenko, and М. С. Лазненко. "Патологічна анатомія і мистецтво." Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/45093.

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Вступ. Мистецтво —це вид людської діяльності, що відбиває дійсність у конкретно-чуттєвих образах, відповідно до певних естетичних ідеалів. Мистецтво включає в себе багато стилів і напрямів і патологічна анатомія не є виключенням. Мета: Дослідити актуальність теми патологічної анатомії в мистецтві, починаючи з минулих сторіч до сучасності.
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Guo, Dongli. "Expression of Wnt signaling targets and their clinico-pathological significance in colorectal neoplasm a tissue microarray study /." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B38610541.

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Oeschger, Franziska M. "Subplate populations in normal and pathological cortical development." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:686d99bd-36e0-47f2-9680-9874f413d1bb.

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The subplate layer of the cerebral cortex is comprised of a heterogeneous population of cells and contains some of the earliest-generated neurons. Subplate plays a fundamental role in cortical development. In the embryonic brain, subplate cells contribute to the guidance and areal targeting of corticofugal and thalamic axons. At later stages, these cells are involved in the maturation and plasticity of the cortical circuitry and the establishment of functional modules. In my thesis, I aimed to further characterize the embryonic murine subplate by establishing a gene expression profile of this population at embryonic day 15.5 (E15.5) using laser capture microdissection combined with microarrays. I found over 250 transcripts with presumed higher expression in the subplate at E15.5. Using quantitative RT-PCR, in situ hybridization and immunohistochemistry, I have confirmed specific expression in the E15.5 subplate for 13 selected genes which have not been previously associated with this compartment. In the reeler mutant, the expression pattern of a majority of these genes was shifted in accordance with the altered position of subplate cells. These genes belong to several functional groups and likely contribute to the maturation and electrophysiological properties of subplate cells and to axonal growth and guidance. The roles of two selected genes - cadherin 10 (Cdh10) and Unc5 homologue c (Unc5c) - were explored in more detail. Preliminary results suggest an involvement of Cdh10 in subplate layer organization while Unc5c could mediate the waiting period of subplate corticothalamic axons in the internal capsule. Finally, I compared the expression of a selection of subplate-specific genes (subplate markers) between mouse and rat and found some surprising species differences. Confirmed subplate markers were used to monitor subplate injury in a rat model of preterm hypoxiaischemia and it appeared that deep cortical layers including subplate showed an increased vulnerability over upper layers. Further characterization of subplate-specific genes will allow us to broaden our understanding of molecular mechanisms underlying subplate properties and functions in normal and pathological development.
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Guo, Dongli, and 郭冬麗. "Expression of Wnt signaling targets and their clinico-pathological significance in colorectal neoplasm: a tissuemicroarray study." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B38610541.

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Close, Koenig Tricia. "Betwixt and between : production and commodification of knowledge in a medical school pathological anatomy laboratory in Strasbourg (mid-19th century to 1939)." Strasbourg, 2011. https://publication-theses.unistra.fr/public/theses_doctorat/2011/CLOSE_KOENIG_Tricia_2011.pdf.

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En croisant l'histoire médicale et l'histoire économique, notamment pour saisir et comprendre la production et la commercialisation des analyses médicales de laboratoires, cette thèse rend visible les aspects monétaires et économiques en jeu dans la recherche, l'enseignement et les pratiques médicales et scientifiques. L'émergence des analyses médicales de laboratoire en tant qu'unités économiques, dans un cadre théorique d'économie de la connaissance, est ainsi étudiée à partir d'une étude de cas, l'histoire d'un laboratoire d'anatomie pathologique à la Faculté de médecine de Strasbourg. Cet étude associe une analyse longue durée de la circulation des matériaux, des savoirs et des pratiques en anatomie pathologique à une micro-histoire d'un laboratoire dans l'entre-deux-guerres. Ce travail décrit et contextualise la diversification des activités de laboratoire quand un service commercial est associé à la recherche et à l'enseignement, comme ce fut le cas pour le diagnostic des cancers suite à la création des Centres Anticancéreux en France. Le marché des analyses de laboratoires médicaux ne correspond pas aux modèles économiques des entreprises scientifiques, médicales, ou commerciales : le laboratoire de l'Institut d'Anatomie Pathologique, entre science et service, était une entité commune à la Faculté de médecine et à l'hôpital, avec des pratiques de production et de commercialisation, des échanges académiques et commerciaux, des produits matériels et intellectuels, des rétributions sous formes d'honoraires et d'actes tarifés. Nous présentons ainsi une histoire économique d'une discipline dans laquelle l'argent n'était pas, du moins ouvertement, visible
By superposing medical history and economic history of medical lab services, this thesis reveals economic dynamics to be integral to medical and scientific research, teaching, and practice. The emergence of medical lab analyses as medical and economic entities within a theoretical framework of knowledge-based economies is achieved with a case study of Strasbourg's medical school Institut d'Anatomie Pathologique laboratories. A long duree historical analysis of material circulation, collection, and practices in pathological anatomy is intersected with a micro-history of the laboratories in the interwar period. The description and contextualization of a diversification of laboratory activities when research and teaching activities were complemented with commercial laboratory services, notably for the diagnosis of cancer, are portrayed with supply and demand dynamics and following the creation of the Centres Anticancéreux in France. The market for clinical laboratory work does not wholly fit (classic) models of scientific, medical, or commercial entreprises; the laboratory at the Institut d’Anatomie Pathologique was between science and service, institutional settings between medical school and hospital, practices between knowledge production and commercialization, exchanges between academic moral economies and commerical economies, products between material and intellectual, income between honorariums and fees. This thesis engages with and promotes an economic history of medicine in which money was not (openly) visible
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Books on the topic "Anatomy, Pathological"

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Anatomy. New York: McGraw-Hill, Health Professions Division, 2000.

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Ger, Ralph. Essentials of clinical anatomy. 2nd ed. New York: Parthenon Pub. Group, 1996.

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Ger, Ralph. Essentials of clinical anatomy. Edinburgh: Churchill Livingstone, 1989.

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Ger, Ralph. Essentials of clinical anatomy. London: Pitman, 1986.

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D, Oppenheimer Ernst M., ed. The Netter Collection of medical illustrations. Summit, NJ: Novartis, 1997.

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Pathological and regenerative plant anatomy. Berlin: Gebrüder Borntraeger, 1999.

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Siegfried, Fink. Pathological and regenerative plant anatomy. Berlin: Gebrüder Borntraeger, 1999.

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C, Toy Eugene, ed. Anatomy. 2nd ed. New York: McGraw-Hill Medical, 2008.

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F, Dalley Arthur, and Agur A. M. R, eds. Clinically oriented anatomy. 6th ed. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins, 2010.

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Clinically oriented anatomy. 2nd ed. Baltimore: Williams & Wilkins, 1985.

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Book chapters on the topic "Anatomy, Pathological"

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Deixonne, B., C. Marty-Double, and C. Pignodel. "Pathological Anatomy." In Exocrine Pancreatic Cancer, 11–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71178-7_2.

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Böhm, Michael, and Erland Erdmann. "Normal and Pathological Anatomy." In Chronic Heart Failure, 13–15. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-85913-7_3.

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Caiaffa, V., D. De Vita, M. Di Viesto, and G. Solarino. "Epidemiology and Pathological Anatomy." In Fractures of the Tibial Pilon, 3–12. Milano: Springer Milan, 2002. http://dx.doi.org/10.1007/978-88-470-2123-5_1.

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Dennison, John, Charles Oxnard, and Peter Obendorf. "Pathological Anatomy and Histology." In Endemic Cretinism, 83–144. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4614-0281-7_6.

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Vital, Jean Marc. "The Normal and Pathological Spinal Muscle." In Spinal Anatomy, 251–72. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-20925-4_18.

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Phadnis, Joideep, and Gregory I. Bain. "Clavicle Anatomy." In Normal and Pathological Anatomy of the Shoulder, 71–80. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45719-1_8.

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Müller-Gerbl, Magdalena. "Pathological Mineralization Patterns." In Advances in Anatomy Embryology and Cell Biology, 77–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72019-2_6.

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Orellana, Juan, and Alan H. Friedman. "Anatomy and Embryology." In Clinico-Pathological Atlas of Congenital Fundus Disorders, 3–10. New York, NY: Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4613-9320-7_1.

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Nobukawa, Bunsei. "Vascular Anatomy of the Pancreas." In Pancreas - Pathological Practice and Research, 8–11. Basel: KARGER, 2007. http://dx.doi.org/10.1159/000100381.

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Kibler, William Ben, and Aaron Sciascia. "Anatomy of Scapula Winging." In Normal and Pathological Anatomy of the Shoulder, 293–300. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45719-1_29.

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Conference papers on the topic "Anatomy, Pathological"

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Wang, Bo, K. Wei Liu, K. Marcel Prastawa, Andrei Irima, Paul M. Vespa, John D. van Horn, P. Thomas Fletcher, and Guido Gerig. "4D active cut: An interactive tool for pathological anatomy modeling." In 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI 2014). IEEE, 2014. http://dx.doi.org/10.1109/isbi.2014.6867925.

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Song Hu. "Multi-parametric photoacoustic microscopy of pathological remodeling in vascular anatomy and function." In 2015 IEEE Photonics Conference (IPC). IEEE, 2015. http://dx.doi.org/10.1109/ipcon.2015.7323619.

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Warrick, Amanda E., J. Douglas Swarts, and Samir N. Ghadiali. "Fluid Structure Interactions in the Eustachain Tube Under Normal and Pathological Conditions." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-175328.

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Cleft Palate is a craniofacial syndrome in which the two plates that form the hard palate are not completely joined. As a result, the soft tissue anatomy of the Eustachian Tube (ET) is altered. The ET is a collapsible tube which connects the middle ear (ME) with the nasopharynx (NP). The ET must be periodically opened to equalize ME and NP pressures and drain ME fluids. In healthy adults, ET openings occur during swallowing, where muscle contraction deforms the surrounding soft tissue. However, changes in tissue anatomy may lead to ET dysfunction (i.e. closure during swallowing) and the development of ME disorders such as Otitis Media (OM)[1]. These disorders are especially problematic in infants with cleft palate as they hinder speech, hearing and psychosocial development. Although surgical procedures can be used to repair a cleft palate, these procedures do not typically account the possible development of ET dysfunction and/or OM.
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Menschikova, Natalia Valeryevna, Eduard Eduardovich Abramkin, and Igor Yuryevich Makarov. "THE POSSIBILITIES OF USING DISTANCE LEARNING METHODS IN THE PRACTICE OF TEACHING PATHOLOGICAL ANATOMY." In Наука и практика в медицине. Благовещенск: Амурская государственная медицинская академия, 2022. http://dx.doi.org/10.22448/9785604863305_105.

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Vieira, Daniella Serafin Couto, Bráulio Leal Fernandes, Érica Elaine Traebert Simezo, Amanda Amaro Pereira, and Mara Scheffer. "STANDARDIZATION OF THE LABORATORY RESEARCH PROTOCOL AND ANATOMOPATHOLOGICAL DIAGNOSIS OF BREAST GRANULOMATOUS INJURIES." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1020.

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Introduction: Granulomatous breast lesions are multifactorial conditions, with clinical, mammographic, and ultrasound findings like those observed in cases of breast carcinoma. Histological evaluation can present key characteristics to define the lesion pattern. Although this entity is rarely reported in the literature, it is associated with inflammatory conditions such as Ductal Ectasia and foreign body reaction. However, it can also be associated with agents such as bacteria, fungi, and parasites. Furthermore, idiopathic causes and exclusion diagnosis, such as sarcoidosis, can be included in the etiology of the process. Objectives: To establish a correlation between the anatomopathological diagnosis and the laboratory investigation by culture for breast granulomatous lesions diagnosis, with validation of the sample’s analysis protocol. Methods: Samples were selected from 17 women treated at the Mastology Service of a Public Hospital in Brazil, with a history and physical examination that raised suspicion of breast granulomatous lesion and they had previous clinical indication of breast core biopsy. The collection of samples was guided by ultrasonography (USG). In turn, they were stored in a blood culture flask (BD BACTECTM) to perform culture tests by automation (VITEK2), bacterioscopy and fungi exams, and acid resistant bacillus (ARB) tests at the Laboratory of Clinical Analyses. Simultaneously, core biopsy samples, fixed in 10% buffered formaldehyde, were sent to a Laboratory of Pathological Anatomy, for a morphological evaluation and research of ARB, fungi, and other bacteria, using the Ziehl-Nielsen, Grocott, PAS and GRAM histochemical methods. Results: Of the 17 samples, 11 had a chronic inflammatory response pattern with a non-lobulocentric granulomatous reaction component and one of them had a lymphocytic mastitis pattern. The five patients with morphological pattern of lobulocentric granulomatous mastitis presented positive culture, four for Corynebacterium kroppenstedtil, and one for Staphylococcus hominis. Sensitivity, Specificity, Positive Predictive Value and Negative Predictive Value in this sample was 100%. Conclusion: The clinical and radiological aspects can bring difficulties that obscure the diagnostic and etiological interpretation of granulomatous lesions. Thus, the morphological details observed in the anatomical pathological examination and the use of the laboratory investigation protocol with standardization of histochemical reactions associated with the use of tools for microbiological diagnosis show increased sensitivity and specificity for the detection of specific etiologic agents in granulomatous mastitis.
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Blahuta, Jiri, Tomas Soukup, Jan Lavrincik, Lukas Pavlik, and Jiri Kozel. "MEASURING AND EVALUATION OF THE ECHOGENICITY GRADE OF SUBSTANTIA NIGRA IN MRI SEQUENCES VS B-MODE ULTRASOUND IMAGING USING THE SAME ALGORITHM: PILOT COMPARISON STUDY." In 22nd SGEM International Multidisciplinary Scientific GeoConference 2022. STEF92 Technology, 2022. http://dx.doi.org/10.5593/sgem2022/2.1/s07.08.

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Diagnostic ultrasound (US) and magnetic resonance imaging (MRI) are important medical imaging methods in modern radiology. Our research is focused on imaging brain structures in neurology. In this paper we present differences of digital image analysis of the substantia nigra (SN) between US and MRI using the same algorithm. In the past, we developed an application for analyzing substantia nigra echogenicity in BMODE US images. Our developed application is based on a principle of binary thresholding in Region of Interest (ROI) to evaluate echogenicity grade. Increased echogenicity of SN is one of important markers for Parkinson�s Disease (PD) progress. The goal of this paper is to analyze if the same principle used for US B-MODE imaging is also applicable for different MR sequences to find out SN changes. From the achieved results detectable SN changes using MRI are possible at least as a complementary examination to US imaging. We need to prove if echogenicity index (called Echo-Index) is well reproducible value between two different MR sequences; SWI and T2-TSE; how to distinguish between pathological SN and normal anatomy. In the first pilot analysis, it seems that the principle of Echo-Index measurement could be a starting point to create a new large clinical study in this field. Totally 23 MR images from two different sequences (T1 and T2) were analyzed in this pilot study. However, it seems that Echo-Index cannot distinguish normal and diseased SN.
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7

Fukui, T., M. Aosaki, Y. Uetsuka, K. Iwade, T. Nirei, and K. Hirosawa. "THROMBOEMBOLISM IN PROSTHETIC VALVE ENDOCARDITIS AND ANTICOAGULANT THERAPY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643267.

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The clinical results of thromboembolism (TE) in Patients with prosthetic valVe endocarditis (PVE) and anticoagulant therapy were studied. 22 PVE patients (ll males and females each from 4 to 59 years old, average 32.7) were selected from 1939 patients who had undergone valve replacement at this hospital from 1964 and 1985. The complication frequency of TE and its clinical results, anticoagulant therapy and coagulation tests were investigated. Diagnostic criterion was determined in either of the following two: l) those patients who experienced valve replacement, with at least gradual pyrogenic symptons and inflammation factors such as a large increase in white blood cells, the progress of ESR and positive CRP, also with the same bacterium found more than twice in blood culture, also with the same bacterium found more than twice in blood culture, or 2) those patients who experienced valve replacement, with bacterial verruca found at re-valve replacement or at pathological anatomy. PVE onset took 2 days to 6.5 years (average 407 days) to appear after valve replacement. 8 out of the 22 PVE patients (36.3%) showed complications at TE onset, and 5 out of the 8 patients repeated. Embolism was found in 6 cases of brain, 4 cases of kidney, 2 cases of lung, 2 cases of limbs and 1 case of spleen, and 8 patients all died. On the other hand, 5 complications (22.7%) at bleeding were found in 3 cases of brain, 1 case of duodenum and 1 case of site of replaced aortic valve, and 4 patients died. Anticoagulant therapy was given to 21 out of the 22 PVE patients, and thrombotest (TT) values at TE onset were all less than 30%. Warfarin was administered as anticoagulant. 2 patients were administered with aspirin, but one was given with 250mg aspirin per day together with warfarin, and the other with 330mg aspirin per day alone. TT values at the onset of bleeding were from 10 to 56%. Anticoagulant therapy had been performed to the PVE patients since PVE onset did not yet appear, but complications coagulability by TT values, and all the patients died. In addition to this, complications at bleeding were found many and most of patients died even when the TT values were not so low. Therefore, we believe that the anticoagulant therapy that had been performed after PVE onset still needs further studies.
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8

Pratt, Sheila Alhana, Valeria Sanabria, Ana Soskin, Aurora Rocio Rizzi, and Marcos Cabrera. "ADENOID CYSTIC CARCINOMA OF THE BREAST." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1014.

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Introduction: Adenoid cystic adenoid carcinoma (ACC) of the breast is a rare variant that occurs in large series only in less than 1% of the patients. It has favorable prognosis and morphological resemblance to tumors originating in the salivary glands. Histopathological diagnosis is based on a mixture of proliferating glands, which correspond to the adenoid component and the replication of the basal membrane in the form of cylinders established by the pseudoglandular component. It usually occurs in adult women. Its form of clinical presentation is a painless breast nodule, located in the retroareolar region, without compromise of skin or nipple secretion, of small size and circumscribed limits. Treatment of ACC is not protocolized, although it is accepted that conservative surgery is applicable in most cases. Our goal is to publicize the clinical case of a patient treated in our service and to show some clinical and histopathological aspects of this same rare pathology. Case report: 63-year-old patient, with no history of cancer in the family, menarche at 16 years of age, three full births, 24 months of lactation, menopause at 46 years of age, no hormone replacement therapy. Hypertensive and diabetic, a right breast nodule was self-detected six months before; slow and painless growth that then fistulizes the skin and is accompanied by serohematic secretion of a gelatinous consistency. On physical examination, a 7 cm nodule is felt in lower quadrants, showing elastic consistency and poorly defined edges. No adenopathies in the armpits or neck. Sectional biopsy performed in another service. Pathological anatomy: differential diagnosis between Cystic Hypersecretory Carcinoma and Cystic Secretory Hyperplasia. With the diagnosis of ACC of the right breast, T2N0Mx stage IIa. Mammography: breasts type b, at the junction of lower quadrants of the right breast, dense delimited mass measuring 5x4 cm, no retraction or skin edema. BIRADS V. Ecograph: A mass located in H6 to 3 cm of the nipple with well delimited edges, with heterogeneous characteristics with liquid and solid areas of 5.71 cm x 4.06 cm. BIRADS V. Extensive resection and sentinel node biopsy is performed. Histopathological result revealed ACC G1 of 5.5 cm with no associated in situ carcinoma. No vascular plungers or perineural invasion are observed. Free surgical limits. pT3 Nx.Mx. Immunohistochemistry: RE-; RP-; HER2-;ki67 <14%. Our case showed a neoplastic proliferation consisting of two types of cavity formation; true glandular lights (adenoid component) and pseudo lumens that produce basal membrane material (cylinder component) with eosinophilic basal membrane material, the adenoid component with basophilic mucin and surrounded by myoepithelial cells. Three negative lymph nodes metastasis. Radiation therapy was decided as an adjuvant treatment.
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9

Torquette, Sarah Louredo, Bruno Henrique Gonçalves Almada, Juliana Vieira Queiroz Almeida, and Sérgio Augusto Vieira Cançado. "Case Report: High-grade glioma resection in the Broca area without functional loss." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.305.

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Context: The Broca’s (BA) and Wernicke’s Area (WA) are fundamental for the language function. Surgical interventions in proximal areas can cause functional deficits. The left brain (LB) contains BA and WA in 92.5-97% of the right-handed individuals and 2/3 of the left-handed. The mapping of these functional areas is done with functional magnetic resonance (fMRI), which identifies which cerebral hemisphere is responsible for to the language function. In slow-growing tumor lesions, there might be plasticity in these areas, which allows tumor resection with functional recovery. In high-grade tumors, growth is fast and there is usually no significant plasticity. This article aims to demonstrate that even in high-grade tumors, brain plasticity in language areas can occur. Case report: T.R.P., male, 20 years old, right-handed, with type-2 neurofibromatosis. Evaluated due to the epileptic seizure with a lesion suggestive of high-grade glioma (IV-WHO) affecting the lower frontal gyrus in magnetic resonance imaging. Results: Undergoing surgical resection with awake craniotomy for functional language mapping. Functional studies have shown that the anatomical area corresponding to BA had no function and was surgically removed. T.R.P. evolved without functional deficits and fMRI showed complete resection of the Broca’s area and the anatomo-pathological exam confirmed that the tumor was a high-grade Glioma (IV-WHO). Conclusions: Even in the presence of a fast-growing lesion, the possibility of brain plasticity in the language areas should be considered. When plasticity is found, complete resection of the tumor is possible using invasive brain mapping, which has a direct impact on prognosis and survival.
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