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Dissertations / Theses on the topic 'Ancestral genomes'

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1

Al-Nuaimi, Bashar. "Ancestral Reconstruction and Investigations of Genomics Recombination on Chloroplasts Genomes." Thesis, Bourgogne Franche-Comté, 2017. http://www.theses.fr/2017UBFCD042/document.

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La théorie de l’évolution repose sur la biologie moderne. Toutes les nouvelles espèces émergent d’une espèce existante. Il en résulte que différentes espèces partagent une ascendance commune, telle que représentée dans la classification phylogénétique. L’ascendance commune peut expliquer les similitudes entre tous les organismes vivants, tels que la chimie générale, la structure cellulaire, l’ADN comme matériau génétique et le code génétique. Les individus d’une espèce partagent les mêmes gènes mais (d’ordinaire) différentes séquences d’allèles de ces gènes. Un individu hérite des allèles de l
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2

Damas, Joana Daniela Mendes. "Avian genomics : from improvement of sequenced genomes to ancestral karyotypes and novel patterns of chromosomal evolution." Thesis, Royal Veterinary College (University of London), 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766310.

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3

Brozynska, Marta, Dario Copetti, Agnelo Furtado, et al. "Sequencing of Australian wild rice genomes reveals ancestral relationships with domesticated rice." WILEY, 2017. http://hdl.handle.net/10150/624392.

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The related A genome species of the Oryza genus are the effective gene pool for rice. Here, we report draft genomes for two Australian wild A genome taxa: O. rufipogon-like population, referred to as Taxon A, and O. meridionalis-like population, referred to as Taxon B. These two taxa were sequenced and assembled by integration of short- and long-read next-generation sequencing (NGS) data to create a genomic platform for a wider rice gene pool. Here, we report that, despite the distinct chloroplast genome, the nuclear genome of the Australian Taxon A has a sequence that is much closer to that o
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4

Yang, Kuan. "Ancestral Genome Reconstruction in Bacteria." Diss., Virginia Tech, 2012. http://hdl.handle.net/10919/28091.

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The rapid accumulation of numerous sequenced genomes has provided a golden opportunity for ancestral state reconstruction studies, especially in the whole genome reconstruction area. However, most ancestral genome reconstruction methods developed so far only focus on gene or replicon sequences instead of whole genomes. They rely largely on either detailed modeling of evolutionary events or edit distance computation, both of which can be computationally prohibitive for large data sets. Hence, most of these methods can only be applied to a small number of features and species. In this dissertati
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Gutiérrez, Arumi Armand 1980. "Ancestral genomic submicroscopic inversions of human genome and their relation with multifactorial human diseases." Doctoral thesis, Universitat Pompeu Fabra, 2016. http://hdl.handle.net/10803/454777.

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Significant advances were performed in mapping and characterizing different types of structural variation in the human genome such as point mutations, insertions, deletions, etc. Nevertheless, there is still an important genetic component in multifactorial diseases that it is still unknown. Inversions are chromosome mutations in which a given loci change its orientation respect to a reference and present a balanced genetic material (neutral copy number). Our group developed tools in order to infer some variants of ancestral submicroscopic inversions (0.5 Mb – 5Mb) using computational methods w
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Brennan, Patrick J. "An Investigation of Personal Ancestry Using Haplotypes." University of Toledo / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1501705310326744.

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7

Crouch, Daniel. "Inferring ancestral and biogeographic origin using genome-wide SNP data." Thesis, King's College London (University of London), 2013. https://kclpure.kcl.ac.uk/portal/en/theses/inferring-ancestral-and-biogeographic-origin-using-genomewide-snp-data(e08f9863-9d91-48d2-a50f-f3fbee6269f1).html.

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Statistically predicting the origin of a human DNA sample has proven effective in forensic casework, and is of broad population genetic interest, but many facets of the problem remain unexplored. This thesis consolidates several pieces of work on the genetic prediction of origin; furthering its theory and practice. I begin by examining the performance of straightforward predictive methods when the objective is to correctly determine an individual's origin from one of several closely related genetic groups, e.g. countries within Europe. Of particular interest are the volume of data required to
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8

Jean, Géraldine. "In silico methods for genome rearrangement analysis : from identification of common markers to ancestral reconstruction." Thesis, Bordeaux 1, 2008. http://www.theses.fr/2008BOR13704/document.

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L'augmentation du nombre de génomes totalement séquencés rend de plus en plus efficace l'étude des mécanismes évolutifs à partir de la comparaison de génomes contemporains. L'un des principaux problèmes réside dans la reconstruction d'architectures de génomes ancestraux plausibles afin d'apporter des hypothèses à la fois sur l'histoire des génomes existants et sur les mécanismes de leur formation. Toutes les méthodes de reconstruction ancestrale ne convergent pas nécessairement vers les mêmes résultats mais sont toutes basées sur les trois mêmes étapes : l'identification des marqueurs communs
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Feiner, Nathalie [Verfasser]. "Characterization of cryptic components of the ancestral vertebrate genome / Nathalie Feiner." Konstanz : Bibliothek der Universität Konstanz, 2013. http://d-nb.info/1035067048/34.

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10

Zhao, Ziming. "Exploiting phylogenetics to understand genome evolution in both modern and ancestral organisms." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/48988.

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Computational evolutionary analyses, particularly phylogenetics and ancestral reconstruction, have been extensively exploited under different algorithms and evolutionary models to better understand genome evolution from both small- and large-scale perspectives in order to assign genotypes based on assortment, resolve species relationships and gene annotation issues, further understand gene gain/loss within individual gene families, measure functional divergence among homologs, and infer ancestral character states. These evolutionary studies provide us with insights into biologically relevant i
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Christ, Ryan. "Ancestral trees as weighted networks : scalable screening for genome wide association studies." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:8f382d56-2d5d-4a4f-9b39-41700897e02e.

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Several haplotype-based methods have been developed to identify loci where multiple mutations of low to moderate frequency and effect size modulate disease susceptibility. Most such approaches either do not scale to hundreds of thousands of genomes or do not explicitly model recombination and the block-like structure of haplotypes. Using a novel checkpointing technique and a C-core, vectorized implementation of an Hidden Markov Model (HMM) based on the Li & Stephens Model, at each single nucleotide polymorphism (SNP) along the genome, we obtain a local genetic distance between all pairs of hap
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Danchin, Etienne Gaëtan Jacques. "Reconstruction of ancestral genomic regions by comparative analysis of evolutionary conserved syntenies : Towards reconstructing the genome of the ancestor of all Bilaterian species (Urbilateria)." Aix-Marseille 2, 2004. http://www.theses.fr/2004AIX22070.

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13

Thompson, Katherine L. "Using ancestral information to search for quantitative trait loci in genome-wide association studies." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1372410951.

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14

Alkindy, Bassam. "Combining approaches for predicting genomic evolution." Thesis, Besançon, 2015. http://www.theses.fr/2015BESA2012/document.

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En bio-informatique, comprendre comment les molécules d’ADN ont évolué au cours du temps reste un problème ouvert etcomplexe. Des algorithmes ont été proposés pour résoudre ce problème, mais ils se limitent soit à l’évolution d’un caractèredonné (par exemple, un nucléotide précis), ou se focalisent a contrario sur de gros génomes nucléaires (plusieurs milliardsde paires de base), ces derniers ayant connus de multiples événements de recombinaison – le problème étant NP completquand on considère l’ensemble de toutes les opérations possibles sur ces séquences, aucune solution n’existe à l’heureac
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Anselmetti, Yoann. "Reconstruction conjointe de l’ordre des gènes de génomes actuels et ancestraux et de leur évolution structurale dans un cadre phylogénétique." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1242/document.

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Les années 2000 ont vu l'apparition des technologies de séquençage haut-débit permettant de faire chuter le coût en temps et argent du séquençage du génome complet et ouvrant la perspective à des analyses de la phylogénie des espèces à l'échelle de génome entiers. Dans cette optique des méthodes pour l'inférence de l'histoire évolutive de l'ordre de marqueurs génomiques le long d'un phylogénie ont été développées. Cependant, les assemblages d'une majorité des grands génomes d'eucaryotes demeurent incomplètement résolues et ne permettent donc pas, en tant que tel, leur exploitation pour la reco
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Churchhouse, Claire. "Bayesian methods for estimating human ancestry using whole genome SNP data." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:0cae8a4a-6989-485b-a7cb-0a03fb86096d.

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The past five years has seen the discovery of a wealth of genetics variants associated with an incredible range of diseases and traits that have been identified in genome- wide association studies (GWAS). These GWAS have typically been performed in in- dividuals of European descent, prompting a call for such studies to be conducted over a more diverse range of populations. These include groups such as African Ameri- cans and Latinos as they are recognised as bearing a disproportionately large burden of disease in the U.S. population. The variation in ancestry among such groups must be correctl
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Diallo, Abdoulaye. "Inference of insertion and deletion scenarios for ancestral genome reconstruction and phylogenetic analyses: algorithms and biological applications." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40771.

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This thesis focuses on algorithms related to ancestral genome reconstruction and phylogenetics analyses. Specially, it studies insertion and deletion (indel) in genomic sequences, their utilities for (1) evolutionary studies of species families, (2) multiple alignment and phylogenetic trees reconstruction assessment, and (3) functional DNA sequence annotation. Here, the indel scenarios reconstruction problem is presented, in a likelihood framework, and it can be stated as follows: given a multiple alignment of orthologous sequences and a phylogenetic tree for these sequences, reconstruct the m
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18

Elias, Isaac. "Computational problems in evolution : Multiple alignment, genome rearrangements, and tree reconstruction." Doctoral thesis, KTH, Numerical Analysis and Computer Science, NADA, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4170.

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<p>Reconstructing the evolutionary history of a set of species is a fundamental problem in biology. This thesis concerns computational problems that arise in different settings and stages of phylogenetic tree reconstruction, but also in other contexts. The contributions include:</p><p>• A new distance-based tree reconstruction method with optimal reconstruction radius and optimal runtime complexity. Included in the result is a greatly simplified proof that the NJ algorithm also has optimal reconstruction radius. (co-author Jens Lagergren)</p><p>• NP-hardness results for the most common variati
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19

Ng, Maggie C. Y., Mariaelisa Graff, Yingchang Lu, et al. "Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium." PUBLIC LIBRARY SCIENCE, 2017. http://hdl.handle.net/10150/624640.

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Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for BMI, WHRadjBMI), but few have been identified through screening of the African ancestry genomes. We performed large scale meta-analyses and replications in up to 52,895 individuals for BMI and up to 23,095 individuals for WHRadjBMI from the African Ancestry Anthropometry Genetics Consortium (AAAGC) using 1000 Genomes phase 1 imputed GWAS to improve coverage of both common and low frequency variants in the low linkage disequi
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20

Croteau-Chonka, Damien. "Quantifying Ascertainment Bias and Determining Proxy Ancestral Alleles in Human Genome-Wide Polymorphic Data for Use in the Determination of Human Demographic History." Thesis, Boston College, 2007. http://hdl.handle.net/2345/521.

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Thesis advisor: Gabor T. Marth<br>Thesis advisor: Eric F. Tsung<br>My work is part of an effort in Dr. Gabor Marth's population genetics lab to extend the work of Marth's 2004 Genetics paper "The allele frequency spectrum in genome-wide human variation data reveals signals of differential demographic history in three large world populations" by applying its methods to new datasets. My contribution toward this end has been to create computer code (in Perl and Bash) to quantify ascertainment bias and determine proxy ancestral alleles in human genome-wide polymorphic data for post-doctoral fellow
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21

Baker, Jennifer. "From Comparative Genomics to Synthetic Biology| Using Ancestral Gene Reconstruction Approaches to Test Hypotheses Regarding Proximate Mechanisms in our Evolutionary History." Thesis, The George Washington University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3688029.

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<p> At its core human evolutionary biology seeks to answer the question of how the defining characteristics of modern humans evolved, such as large-brains, obligatory bipedal gait, extended juvenile period, and increased longevity. Traditional fossil-based research uses morphology to infer behavior and life history and only recently have researchers been able to make predictions regarding the effect of modifications to the DNA and proteins of our forbearers. Using these innovative methods we investigated the molecular evolution of a superfamily of transcription factors called the Nuclear Recep
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22

Figuet, Emeric. "Impact génomique des stratégies d'histoire de vie et reconstruction de traits ancestraux chez les amniotes." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS101/document.

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L'élucidation des liens réciproques unissant le génotype et le phénotype constitue un objectif central de la biologie moderne. De nombreux aspects de l'évolution à l'échelle moléculaire sont ainsi connus pour répondre aux caractéristiques démographiques ou d'histoire de vie des espèces. En particulier, la théorie quasi-neutre postule que les petites populations accumulent davantage de substitutions faiblement délétères dans leur génome, en raison d'une dérive génétique accrue. La composition en bases, à travers le mécanisme de la conversion génique biaisée, s'est également révélée obéir à l'in
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23

Teló, Enio Paulo. "Estimativa de mistura étnica avaliada por Mercadores Informativos de Ancestralidade (AIMs) e Microssatélites (STRs)." reponame:Repositório Institucional da FIOCRUZ, 2010. https://www.arca.fiocruz.br/handle/icict/4171.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2012-07-16T21:36:49Z No. of bitstreams: 1 Enio Paulo Estimativa de mistura étnica avaliada por Marcadores Informativos de.pdf: 352598 bytes, checksum: 7d448dc54afe1ec271f59fc912275f41 (MD5)<br>Made available in DSpace on 2012-07-16T21:36:49Z (GMT). No. of bitstreams: 1 Enio Paulo Estimativa de mistura étnica avaliada por Marcadores Informativos de.pdf: 352598 bytes, checksum: 7d448dc54afe1ec271f59fc912275f41 (MD5) Previous issue date: 2010<br>Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Bra
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Romiguier, Jonathan. "Phylogénomique et stratégies d'histoires de vie des mammifères placentaires : apports de la théorie de la conversion génique biaisée." Thesis, Montpellier 2, 2012. http://www.theses.fr/2012MON20222/document.

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Des souris aux baleines en passant par les humains, la diversité écologique des mammifères placentaires est des plus fascinantes. Bien qu'il s'agisse là d'un des groupes les plus étudiés, leur origine fait pourtant l'objet de bien des mystères. Leurs relations de parenté les plus basales restent en effet incertaines, et l'on ignore encore beaucoup du mode de vie qu'avaient nos ancêtres du Crétacé, ces mammifères placentaires qui auraient côtoyé les dinosaures pendant plus de 30 millions d'années.Afin d'aborder ces questions, cette thèse a utilisé l'outil de la génomique comparative. L'une de s
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Lassalle, Florent. "Les génomes bactériens, une histoire de transferts de gènes, de recombinaison et de cladogénèse." Thesis, Lyon 1, 2013. http://www.theses.fr/2013LYO10234/document.

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Dans les génomes bactériens, les fréquents transferts horizontaux de gènes (HGT) introduisent des innovations génomiques qui peuvent entraîner la diversification des populations bactériennes. À l'inverse, la recombinaison homologue (RH) au sein des populations homogénéise leurs génotypes, et ainsi renforce leur cohésion. Ces processus d'échange génétique, et la fréquence à laquelle ils interviennent au sein et entre les populations, doivent avoir un grand impact sur la cladogénèse bactérienne. Au-delà de la configuration des échanges qui se sont réellement produits entre les bactéries, les tra
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Melé, Messeguer Marta. "Incorporating recombination into the study of recent human evolutionary history." Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/22684.

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En aquest treball es pretén utilitzar la informació que deixa la recombinació al nostres genomes per fer inferències sobre la història evolutiva recent de les poblacions humanes. Per fer-ho, s’ha desenvolupat un mètode novedós, anomenat IRiS, que permet la detecció de recombinacions antigues específiques en un conjunt de seqüències. Hem validat extensivament IRiS i l'hem sotmès a diferents escenaris per tal d’avaluar-ne l’ eficàcia. Un cop els events de recombinació són detectats, es poden utilitzar com a marcadors genètics per estudiar els patrons de diversitat de les poblacions humanes. Fin
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Bomfim, Thais Ferreira. "Análise de ancestralidade genômica e de polimorfismos associados à pigmentação da pele em amerídios e em descendentes de africanos, de europeus e de japoneses." reponame:Repositório Institucional da FIOCRUZ, 2012. https://www.arca.fiocruz.br/handle/icict/4311.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2012-08-30T21:44:55Z No. of bitstreams: 1 Thais Ferreira Bonfim. Ancestralidade genômica em uma amostra de portadores do HIV-1 do Estado da Bahia - CPqGM - Dissertação de Mestrado - 2008.pdf: 2375743 bytes, checksum: 3d0b1edd686e7965b81d1f26113f0f78 (MD5)<br>Made available in DSpace on 2012-08-30T21:44:55Z (GMT). No. of bitstreams: 1 Thais Ferreira Bonfim. Ancestralidade genômica em uma amostra de portadores do HIV-1 do Estado da Bahia - CPqGM - Dissertação de Mestrado - 2008.pdf: 2375743 bytes, checksum: 3d0b1edd686e7965b
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Fernandes, Francisco José de Almeida. "Caracterização da estrutura de dependência do genoma humano usando campos markovianos: estudo de populações mundiais e dados de SNPs." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/45/45133/tde-23032016-134721/.

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A identificação de regiões cromossômicas, ou blocos de dependência dentro do genoma humano, que são transmitidas em conjunto para seus descendentes (haplótipos) tem sido um desafio e alvo de várias iniciativas de pesquisa, muitas delas utilizando dados de plataformas de marcadores moleculares do tipo SNP (Single Nucleotide Polymorphisms - SNPs), com alta densidade dentro do DNA humano. Este trabalho faz uso de uma modelagem estocástica de campos Markovianos de alcance variável, em uma amostra estratificada de diferentes populações, para encontrar blocos de SNPs, independentes entre si, estrutu
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Fortes, Lima César Augusto. "Tracing the genetic origin of african descendants from South America." Thesis, Toulouse 3, 2015. http://www.theses.fr/2015TOU30237/document.

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Introduction La traite transatlantique, du 15ième au 19ième siècle, a changé radicalement la démographie des Amériques. Des milliers d'esclaves africains ont réussi à échapper aux plantations des colonisateurs européens, et ont formé des colonies indépendantes de peuples libres (ou 'Marron'). Dans notre travail, nous étudions quatre communautés Noir Marron de la Guyane française et du Surinam, ainsi que d'autres populations ayant un héritage africain : Brésil et Colombie, ainsi que des populations d'Afrique de l'Ouest : Bénin, Côte-d'Ivoire et Mali. Afin de définir les différentes histoires dé
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Brito, Luciano Abreu. "Identificação de genes de suscetibilidade às fissuras labiopalatinas não sindrômicas: influência da epidemiologia e da estratificação populacional." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-26092011-163108/.

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Fissura labial com ou sem fissura de palato não sindrômica (FL±P NS) é uma doença complexa que afeta 1:700 indivíduos no mundo. A busca das causas genéticas dessa malformação é dificultada pelo padrão multifatorial de herança e pela heterogeneidade genética, sendo que o gene IRF6 e a região 8q24 são os loci de associação mais corroborada. A estratificação populacional é um problema adicional a ser considerado em estudos de caso-controle na população brasileira. No intuito de caracterizar variáveis que possam interferir na busca dos fatores de risco, realizamos em um primeiro estudo uma avaliaç
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Gagnon, Yves. "Algorithmes pour la reconstruction de génomes ancestraux." Thèse, 2012. http://hdl.handle.net/1866/8634.

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L’inférence de génomes ancestraux est une étape essentielle pour l’étude de l’évolution des génomes. Connaissant les génomes d’espèces éteintes, on peut proposer des mécanismes biologiques expliquant les divergences entre les génomes des espèces modernes. Diverses méthodes visant à résoudre ce problème existent, se classant parmis deux grandes catégories : les méthodes de distance et les méthodes de synténie. L’état de l’art des distances génomiques ne permettant qu’un certain répertoire de réarrangements pour le moment, les méthodes de synténie sont donc plus appropriées en pratique. Nous pro
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Ma, Jian. "Reconstructing contiguous regions of an ancestral genome." 2006. http://etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-1643/index.html.

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Pillay, Ellisha. "In vitro culture and genetic transformation of selected ancestral and commercial sugarcane germplasm." Thesis, 2013. http://hdl.handle.net/10413/10064.

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Sugarcane is an economically important crop and its high demand has necessitated the use of biotechnology methods to produce and accelerate the production of desirable genotypes. One such method is genetic transformation. However, as sugarcane is a highly polyploid crop, which originated from interspecific crosses between Saccharum spontaneum and S. officinarum, efforts to transform it are inhibited by transgene promoter silencing. As ancestral lines have a simpler genetic makeup than modern varieties, they may be useful to test promoter function. Intrinsic to the generation of transgenic plan
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Sawler, Jason. "Genomic Ancestry Estimation in Interspecific Grape Hybrids." 2014. http://hdl.handle.net/10222/49111.

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The genus Vitis (the grapevine) is a group of highly diverse, diploid woody perennial vines consisting of approximately 60 species from across the northern hemisphere. To gain insights into the use of wild Vitis species during the past century of interspecific grape breeding and to provide a foundation for marker- assisted breeding programmes, we present a principal components analysis based ancestry estimation method to calculate admixture proportions of hybrid grapes in the United States Department of Agriculture grape germplasm collection using genome-wide polymorphism data. We find that gr
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Halder, Indrani. "Measuring and using individual genomic ancestry to study complex phenotypes." 2005. http://www.etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-1038/index.html.

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Tremblay, Savard Olivier. "Étude de l’évolution des génomes par duplications, pertes et réarrangements." Thèse, 2013. http://hdl.handle.net/1866/11311.

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La duplication est un des évènements évolutifs les plus importants, car elle peut mener à la création de nouvelles fonctions géniques. Durant leur évolution, les génomes sont aussi affectés par des inversions, des translocations (incluant des fusions et fissions de chromosomes), des transpositions et des délétions. L'étude de l'évolution des génomes est importante, notamment pour mieux comprendre les mécanismes biologiques impliqués, les types d'évènements qui sont les plus fréquents et quels étaient les contenus en gènes des espèces ancestrales. Afin d'analyser ces différents aspects de l'évo
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Blaschikoff, Ludmilla Paixão. "Dogs (Canis lupus familiaris) from the Iberian Peninsula dated to the Chalcolithic period: a genomic approach." Master's thesis, 2019. http://hdl.handle.net/10773/26896.

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Os cães existem na Península Ibérica pelo menos desde o Paleolítico Superior; o resto arqueológico mais antigo data há cerca de 16,000 AP (Erralla, Espanha). Existem diferentes teorias sobre a origem dos cães na Europa. Estudos anteriores indicam que os cães podem ter chegado à Europa a partir de uma população domesticada de lobos oriundos da Ásia Oriental, ou a partir de duas populações de lobos geneticamente distintas da Eurásia Oriental e Ocidental, domesticadas independentemente, e que mais tarde, a população de cães da Eurásia Oriental se espalhou e substituiu parcialmente a popula
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38

Oliveira, Marisa Sofia Sousa. "Genomic and functional insights on dengue infections: the role of host ancestry." Tese, 2018. https://hdl.handle.net/10216/115207.

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39

Oliveira, Marisa Sofia Sousa. "Genomic and functional insights on dengue infections: the role of host ancestry." Doctoral thesis, 2018. https://hdl.handle.net/10216/115207.

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40

"A STR system tailored for identification of the Chinese Han population." 2002. http://library.cuhk.edu.hk/record=b6073470.

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Abstract:
Xiang Hai Liao.<br>"July 2002."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2002.<br>Includes bibliographical references (p. 180-200).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.
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