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Journal articles on the topic 'And anticancer activities'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Gupta, Salin, David Zhang, Jizu Yi, and Jun Shao. "Anticancer Activities ofOldenlandia diffusa." Journal of Herbal Pharmacotherapy 4, no. 1 (2004): 21–33. http://dx.doi.org/10.1080/j157v04n01_03.

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2

Li, Dong Hong, Jun Lin Diao, Ke Gui Yu, and Cheng He Zhou. "Synthesis and anticancer activities of porphyrin induced anticancer drugs." Chinese Chemical Letters 18, no. 11 (2007): 1331–34. http://dx.doi.org/10.1016/j.cclet.2007.09.012.

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3

Gupta, Salin, David Zhang, Jizu Yi, and Jun Shao. "Anticancer Activities of Oldenlandia diffusa." Journal Of Herbal Pharmacotherapy 4, no. 1 (2004): 21–33. http://dx.doi.org/10.1300/j157v04n01_03.

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4

Karthikeyan, Chandrabose, Narayana S. H. Narayana Moorthy, Sakthivel Ramasamy, et al. "Advances in Chalcones with Anticancer Activities." Recent Patents on Anti-Cancer Drug Discovery 10, no. 1 (2014): 97–115. http://dx.doi.org/10.2174/1574892809666140819153902.

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5

Syam, Suvitha, Siddig Ibrahim Abdelwahab, Mohammed Ali Al-Mamary, and Syam Mohan. "Synthesis of Chalcones with Anticancer Activities." Molecules 17, no. 6 (2012): 6179–95. http://dx.doi.org/10.3390/molecules17066179.

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6

Zhong, Mei, Yanjuan Liu, Junxi Liu, et al. "Isocorydine Derivatives and Their Anticancer Activities." Molecules 19, no. 8 (2014): 12099–115. http://dx.doi.org/10.3390/molecules190812099.

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7

Safe, Stephen, Vijayalekshmi Nair, and Keshav Karki. "Metformin-induced anticancer activities: recent insights." Biological Chemistry 399, no. 4 (2018): 321–35. http://dx.doi.org/10.1515/hsz-2017-0271.

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AbstractMetformin is a widely used antidiabetic drug, and there is evidence among diabetic patients that metformin is a chemopreventive agent against multiple cancers. There is also evidence in human studies that metformin is a cancer chemotherapeutic agent, and several clinical trials that use metformin alone or in combination with other drugs are ongoing.In vivoandin vitrocancer cell culture studies demonstrate that metformin induces both AMPK-dependent and AMPK-independent genes/pathways that result in inhibition of cancer cell growth and migration and induction of apoptosis. The effects of

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8

Lee, Kwon-Jai, Jeung Hee An, Kang-Hyun Chung, Jae-Soo Shin, and Dong-Hee Kim. "Anticancer Activities of Silver-Coated Maghemite." Science of Advanced Materials 6, no. 11 (2014): 2435–39. http://dx.doi.org/10.1166/sam.2014.2191.

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9

Jeleń, M., K. Pluta, K. Suwińska, B. Morak-Młodawska, M. Latocha, and A. Shkurenko. "Quinonaphthothiazines, syntheses, structures and anticancer activities." Journal of Molecular Structure 1099 (November 2015): 10–15. http://dx.doi.org/10.1016/j.molstruc.2015.06.046.

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10

Li, Suping, Qiao Jiang, Baoquan Ding, and Guangjun Nie. "Anticancer Activities of Tumor-killing Nanorobots." Trends in Biotechnology 37, no. 6 (2019): 573–77. http://dx.doi.org/10.1016/j.tibtech.2019.01.010.

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11

Zhaowen, Lou, Zhou Li, Xiao Chunfen, Ye Yong, Zeng Fanbo, and Huang Kaixun. "Anticancer activities of some arylcarbamoylalkyltriphenylphosphonium chlorides." Medicinal Chemistry Research 16, no. 7-9 (2007): 380–91. http://dx.doi.org/10.1007/s00044-007-9050-7.

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12

Bolden, Jessica E., Melissa J. Peart, and Ricky W. Johnstone. "Anticancer activities of histone deacetylase inhibitors." Nature Reviews Drug Discovery 5, no. 9 (2006): 769–84. http://dx.doi.org/10.1038/nrd2133.

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13

Wellington, Kevin W., Vincent Hlatshwayo, Natasha I. Kolesnikova, Sourav Taru Saha, Mandeep Kaur, and Lesetja R. Motadi. "Anticancer activities of vitamin K3 analogues." Investigational New Drugs 38, no. 2 (2019): 378–91. http://dx.doi.org/10.1007/s10637-019-00855-8.

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14

Gaber, Ahmed, Walaa F. Alsanie, Deo Nandan Kumar, Moamen S. Refat, and Essa M. Saied. "Novel Papaverine Metal Complexes with Potential Anticancer Activities." Molecules 25, no. 22 (2020): 5447. http://dx.doi.org/10.3390/molecules25225447.

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Cancer is one of the leading causes of death worldwide. Although several potential therapeutic agents have been developed to efficiently treat cancer, some side effects can occur simultaneously. Papaverine, a non-narcotic opium alkaloid, is a potential anticancer drug that showed selective antitumor activity in various tumor cells. Recent studies have demonstrated that metal complexes improve the biological activity of the parent bioactive ligands. Based on those facts, herein we describe the synthesis of novel papaverine–vanadium(III), ruthenium(III) and gold(III) metal complexes aiming at en

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15

Maumela, Pfariso, and Mahloro Hope Serepa-Dlamini. "In Silico Analysis of Novel Bacterial Metabolites with Anticancer Activities." Metabolites 14, no. 3 (2024): 163. http://dx.doi.org/10.3390/metabo14030163.

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Resistance to anticancer therapeutics is a major global concern. Thus, new anticancer agents should be aimed against novel protein targets to effectively mitigate the increased resistance. This study evaluated the potential of secondary metabolites from a bacterial endophyte, as new anticancer agents, against a novel protein target, fibroblast growth factor. In silico genomic characterization of the Bacillus sp. strain MHSD_37 was used to identify potential genes involved in encoding secondary metabolites with biological activity. The strain was also exposed to stress and liquid chromatography

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16

Bahashwan, Saleh A. "Pharmacological activities of some triazinopyrazolothieno pyrimidine derivatives." Acta Pharmaceutica 67, no. 3 (2017): 407–14. http://dx.doi.org/10.1515/acph-2017-0022.

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Abstract Triazinopyrazolothieno pyrimidine derivatives 1–5 were evaluated for their anti-inflammatory, analgesic and anticancer activities and acute toxicity. Anti-inflammatory activity of the compounds was studied using the carrageenan test. All tested compounds showed analgesic activity, 3-methoxycarbonyl-4,6-dimethyl-8-[(N-methylindolyl)methyl] pyrimido [5′,4′:4,5]thieno [3′,2′-3,4]pyrazolo [5,1-c]triazine (4) showed activity comparable to that of diclofenac. Compounds 1–5 were also screened for anticancer activity on a human lung cancer cell line (A549) and a human prostate cancer cell lin

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17

Matulja, Dario, Karlo Wittine, Nela Malatesti, et al. "Marine Natural Products with High Anticancer Activities." Current Medicinal Chemistry 27, no. 8 (2020): 1243–307. http://dx.doi.org/10.2174/0929867327666200113154115.

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This review covers recent literature from 2012-2019 concerning 170 marine natural products and their semisynthetic analogues with strong anticancer biological activities. Reports that shed light on cellular and molecular mechanisms and biological functions of these compounds, thus advancing the understanding in cancer biology are also included. Biosynthetic studies and total syntheses, which have provided access to derivatives and have contributed to the proper structure or stereochemistry elucidation or revision are mentioned. The natural compounds isolated from marine organisms are divided i

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18

Filho, Eclair Venturini, Erick M. C. Pinheiro, Sergio Pinheiro, and Sandro J. Greco. "Aminopyrimidines: Recent synthetic procedures and anticancer activities." Tetrahedron 92 (July 2021): 132256. http://dx.doi.org/10.1016/j.tet.2021.132256.

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19

Ahmad, Bashir, Suliman Khan, Yang Liu, et al. "Molecular Mechanisms of Anticancer Activities of Puerarin." Cancer Management and Research Volume 12 (January 2020): 79–90. http://dx.doi.org/10.2147/cmar.s233567.

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20

B. Ng, T., and J. H. Wong. "Fungal Proteins with Antiproliferative and Anticancer Activities." Protein & Peptide Letters 20, no. 4 (2013): 433–38. http://dx.doi.org/10.2174/092986613805290363.

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21

B. Ng, T., and J. H. Wong. "Fungal Proteins with Antiproliferative and Anticancer Activities." Protein & Peptide Letters 20, no. 4 (2013): 433–38. http://dx.doi.org/10.2174/0929866511320040007.

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22

Hoskin, David W., and Ayyalusamy Ramamoorthy. "Studies on anticancer activities of antimicrobial peptides." Biochimica et Biophysica Acta (BBA) - Biomembranes 1778, no. 2 (2008): 357–75. http://dx.doi.org/10.1016/j.bbamem.2007.11.008.

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23

Shi, Zhi, You-Qiu Xue, Ke-Jun Cheng, et al. "Antioxidant and Anticancer Activities of Raspberry Extracts." Journal of Cancer Research Updates 4, no. 2 (2015): 54–59. http://dx.doi.org/10.6000/1929-2279.2015.04.02.2.

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24

Megges, Rudolf, Jürgen Weiland, Rudolf Schön, Heinrich Repke, and Kurt R. H. Repke. "Cardenamides from Cardenolides: Cardiac and Anticancer Activities." Collection of Czechoslovak Chemical Communications 67, no. 3 (2002): 336–52. http://dx.doi.org/10.1135/cccc20020336.

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Two ways are shown to transform cardioactive cardenolides into cardenamides [17β-(5-oxo-2,5-dihydropyrrol-3-yl)-5β,14β-androstane derivatives], and their derivatives by replacement of their ring oxygen by N-R. Cardioactivity is strongly decreased by this transformation. The comparatively easily accessible 21-oxocardenamides [17β-(2-maleimidyl)steroids] are strongly thiol reactive and show remarkable anticancer activity.

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25

dos Santos, Edson Lucas, Débora da Silva Baldivia, Daniel Ferreira Leite, et al. "Antioxidant and anticancer activities from Stryphnodendron adstringens." Free Radical Biology and Medicine 128 (November 2018): S66. http://dx.doi.org/10.1016/j.freeradbiomed.2018.10.136.

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26

Hou, Yani, Congshan Shang, Hui Wang, and Jie Yun. "Isatin–azole hybrids and their anticancer activities." Archiv der Pharmazie 353, no. 1 (2019): 1900272. http://dx.doi.org/10.1002/ardp.201900272.

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27

Song, Xu‐Feng, Jing Fan, Lan Liu, Xiao‐Feng Liu, and Feng Gao. "Coumarin derivatives with anticancer activities: An update." Archiv der Pharmazie 353, no. 8 (2020): 2000025. http://dx.doi.org/10.1002/ardp.202000025.

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28

Zhang, Longfei, and Zhi Xu. "Coumarin-containing hybrids and their anticancer activities." European Journal of Medicinal Chemistry 181 (November 2019): 111587. http://dx.doi.org/10.1016/j.ejmech.2019.111587.

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29

Al-Rajhi, Aisha M. H., Reham Yahya, Tarek M. Abdelghany, et al. "Anticancer, Anticoagulant, Antioxidant and Antimicrobial Activities of Thevetia peruviana Latex with Molecular Docking of Antimicrobial and Anticancer Activities." Molecules 27, no. 10 (2022): 3165. http://dx.doi.org/10.3390/molecules27103165.

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Natural origin molecules represent reliable and excellent sources to overcome some medicinal problems. The study of anticancer, anticoagulant, and antimicrobial activities of Thevetia peruviana latex were the aim of the current research. An investigation using high-performance liquid chromatography (HPLC) revealed that the major content of the flavonoids are rutin (11.45 µg/mL), quersestin (7.15 µg/mL), naringin (5.25 µg/mL), and hisperdin (6.07 µg/mL), while phenolic had chlorogenic (12.39 µg/mL), syringenic (7.45 µg/mL), and ferulic (5.07 µg/mL) acids in latex of T. peruviana. Via 1,1-diphen

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30

Yang, Mingli, Hailin Liu, Yazhou Zhang, Xiujun Wang, and Zhi Xu. "Moxifloxacin-isatin Hybrids Tethered by 1,2,3-triazole and their Anticancer Activities." Current Topics in Medicinal Chemistry 20, no. 16 (2020): 1461–67. http://dx.doi.org/10.2174/1568026620666200128144825.

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Aims: To explore more active fluoroquinolone anticancer candidates. Background: Cancer which can affect almost any part of the body, is most striking and deadliest disease. It is estimated that around one in five people globally develop cancer during their lifetime, and approximately 10% people eventually die from this disease, and 18.1 million new cancer cases with 9.6 million deaths occurred in 2018. The anticancer agents play an intriguingly role in fighting against cancer, and above 100 drugs have already been marketed for this purpose. However, the major drawback of current accessible ant

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31

Mohamedahmed, Shaza M., Muhamad Noor Alfarizal Kamarudin, Premdass Ramdas, Ali Qusay Khalid, Usha Sundralingam, and Ammu Kutty Radhakrishnan. "Anticancer activities of tocotrienols: A Systematic Scoping Review." F1000Research 12 (August 16, 2024): 402. http://dx.doi.org/10.12688/f1000research.132031.2.

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Background: The increasing number of cancer cases requires developing newer approaches to treat this disease. One approach uses natural compounds with known anticancer effects, such as tocotrienols. Many cell-based and animal-model studies found that tocotrienols possess potent anticancer activities. However, the exact molecular regulatory mechanism through which tocotrienols exert anticancer actions remains unclear. Methods: This scoping review analysed data from original research articles reporting on the anticancer effects of tocotrienols on human cancer cell lines published in the last sev

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32

Mohamedahmed, Shaza M., Muhamad Noor Alfarizal Kamarudin, Premdass Ramdas, Ali Qusay Khalid, Usha Sundralingam, and Ammu Kutty Radhakrishnan. "Anticancer activities of tocotrienols: A Systematic Scoping Review." F1000Research 12 (April 14, 2023): 402. http://dx.doi.org/10.12688/f1000research.132031.1.

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Background: The increasing number of cancer cases requires developing newer approaches to treat this disease. One approach uses natural compounds with known anticancer effects, such as tocotrienols. Many cell-based and animal-model studies found that tocotrienols possess potent anticancer activities. However, the exact molecular regulatory mechanism through which tocotrienols exert anticancer actions remains unclear. Methods: This scoping review analysed data from original research articles reporting on the anticancer effects of tocotrienols on human cancer cell lines published in the last sev

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33

Sridevi Subramonie, Nagaraja Suryadevara, Balavinayagamani Ganapathy, and Gokila Devi T. "Molecular activities in Moringa oleifera Linn - Review." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 140–47. http://dx.doi.org/10.26452/ijrps.v11i1.1798.

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The terrific increase by the word "modernization" in various fields in the world without boundaries affects the total environmental system, which leads to the emergence of various new diseases in various forms. In that case, cancer is considered as one of such a dreadful disease which is also measured as a leading cause for the death of the people. Even with the advanced treatment of modern medicine in treating cancer and reduce the rate of cancer recurrence using advanced technologies such as immunotherapy, targeted therapy, robotic radiosurgery are still very subjective to the individual, an

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34

Khalivulla, Shaik I., Arifullah Mohammed, Kuttulebbai N. S. Sirajudeen, Mannur I. Shaik, Weibing Ye, and Mallikarjuna Korivi. "Novel Phytochemical Constituents and Anticancer Activities of the Genus, Typhonium." Current Drug Metabolism 20, no. 12 (2020): 946–57. http://dx.doi.org/10.2174/1389200220666191118102616.

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Background: Typhonium is the largest genus in the Araceae family (~70 species), distributed in South Asia, Southeast Asia and Australia. Typhonium is well-known for its ethnopharmacological uses, and Southeast Asians consider it as an alternative medicine to treat cancer. This review elucidated the confirmed chemical structures of the isolated compounds of Typhonium and emphasized on their anticancer activities against various human cancer cells. Methods: Among several species, Typhonium blumei, T. flagelliforme, T. divaricatum and T. giganteum were extensively studied due to the presence of a

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35

Chen, Rui, Lini Huo, Yogini Jaiswal, et al. "Design, Synthesis, Antimicrobial, and Anticancer Activities of Acridine Thiosemicarbazides Derivatives." Molecules 24, no. 11 (2019): 2065. http://dx.doi.org/10.3390/molecules24112065.

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Background: Acridine and thiourea derivatives are important compounds in medicinal chemistry due to their diverse biological properties including anticancer and antimicrobial effects. However, literature reveals some side effects associated with use of acridines. It is suggested that hybrid molecules may reduce the side effects and enhance the beneficial properties due to synergistic activity. The objectives of the present study are to synthesize and evaluate the anticancer and antimicrobial properties of new hybrids of acridine thiosemicarbazides derivatives. Results: The structures of the sy

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36

Swantara, Made Dira, Wiwik Susanah Rita, Nyoman Suartha, and Kadek Karang Agustina. "Anticancer activities of toxic isolate of Xestospongia testudinaria sponge." Veterinary World 12, no. 9 (2019): 1434–40. http://dx.doi.org/10.14202/vetworld.2019.1434-1440.

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Aim: The purposes of this study were to determine the anticancer activity of Xestospongia testudinaria sponge isolate and identify the responsible compounds. Materials and Methods: The metabolites were extracted using methanol maceration at room temperature. The separation and purification of metabolites were performed using fractionation and column chromatography. The toxicity was examined using the brine shrimp lethality assay, and the toxic isolates were tested for anticancer activity against HeLa cells. Gas chromatography-mass spectrometry analysis was used to identify the compounds in the

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37

Rozadi, Novia, Sri Oktavia, and Fitra Fauziah. "Pharmacological Activities of Punicalagin: A Review." Journal of Drug Delivery and Therapeutics 12, no. 2 (2022): 148–55. http://dx.doi.org/10.22270/jddt.v12i2.5377.

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Traditional medicine was becoming more popular as a component of complementary and alternative medicine around the world. The ability to provide information on the pharmacological effects of plants requires a thorough understanding of the chemical components found in plants. One of the chemical compounds reported having pharmacological activity was punicalagin. Punicalagin was a polyphenol compound found in Punica granatum, Lafoensia pacari, and genus Terminalia. This review provides information on the pharmacological activities of punicalagin. The bibliographic databases used as the sources o

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38

Dembitsky, Valery M., and Dmitri O. Levitsky. "Acetylenic Terrestrial Anticancer Agents." Natural Product Communications 1, no. 5 (2006): 1934578X0600100. http://dx.doi.org/10.1177/1934578x0600100512.

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Acetylenic metabolites belong to a class of molecules containing triple bond(s). They are found in plants, fungi, microorganisms, and marine invertebrates. This review presents 139 active acetylenic molecules of plant, fungal, and soil bacterial origin that reveal cytotoxic and/or anticancer activities. Although many compounds of this group possess encouraging characteristics, they have never been evaluated as potential anticancer agents. They are of great interest, especially for the medicine and/or pharmaceutical industries. Here we describe structures and biological activities of acetylenic

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39

Wu, Yuan Seng, Michelle Felicia Lee, Rhanye Mac Guad, et al. "Insights on Anticancer Activities, Associated Phytochemicals and Potential Molecular Mechanisms of Quisqualis indica: A Mini Review." Sains Malaysiana 52, no. 6 (2023): 1749–58. http://dx.doi.org/10.17576/jsm-2023-5206-11.

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Drug resistance is the main issue causing the treatment failure of anticancer drugs. This issue has urged researchers to search for new substances from medicinal plants, which are widely reported as the good sources of anticancer agents. Quisqualis indica is a plant belongs to Combretaceae family, known as Rangoon Creeper, which can be found abundantly in tropical countries and distributed profusely as a wild shrub. It has been widely used traditionally and scientifically claimed to process various therapeutic activities. It has recently been reported to possess various potential anticancer ac

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40

Mohamed Subarkhan, Mohamed Kasim, Rengan Ramesh, and Yu Liu. "Synthesis and molecular structure of arene ruthenium(ii) benzhydrazone complexes: impact of substitution at the chelating ligand and arene moiety on antiproliferative activity." New Journal of Chemistry 40, no. 11 (2016): 9813–23. http://dx.doi.org/10.1039/c6nj01936f.

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41

Rani, Priyanka, Dilipkumar Pal, Rahul Rama Hegde, and Syed Riaz Hashim. "Anticancer, Anti-Inflammatory, and Analgesic Activities of Synthesized 2-(Substituted phenoxy) Acetamide Derivatives." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/386473.

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The aphorism was to develop new chemical entities as potential anticancer, anti-inflammatory, and analgesic agents. The Leuckart synthetic pathway was utilized in development of novel series of 2-(substituted phenoxy)-N-(1-phenylethyl)acetamide derivatives. The compounds containing 1-phenylethylamine as basic moiety attached to substituted phenols were assessed for their anticancer activity against MCF-7 (breast cancer), SK-N-SH (neuroblastoma), anti-inflammatory activity, and analgesic activity. These investigations revealed that synthesized products3a–jwith halogens on the aromatic ring favo

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42

Özşen Batur, Ö., Ö. Atlı, and İ. Kıran. "Biotransformation of oleic acid and antimicrobial and anticancer activities of its biotransformatıon extracts." Bulgarian Chemical Communications 51, no. 2 (2019): 200–205. http://dx.doi.org/10.34049/bcc.51.2.4831.

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Oleic acid is an unsaturated fatty acid found in significant quantities in various edible oils. Scientific studies have shown that oleic acid and its derivatives exhibit a variety of biological activities including antimicrobial and anticancer activities. In the present work, biotransformation of oleic acid was carried out initially using 27 different microbial strains. Extracts obtained from biotransformation with Alternaria alternata (clinical isolate) and Aspergillus terreus var. africanus (clinical isolate) were used in antimicrobial and anticancer activity studies. The in vitro antimicrob

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43

Betts, Lynn M., Nga Chiu Tam, S. M. Humayun Kabir, Richard F. Langler, and Ian Crandall. "Ether Aryl Sulfonic Acid Esters with Improved Antimalarial/Anticancer Activities." Australian Journal of Chemistry 59, no. 4 (2006): 277. http://dx.doi.org/10.1071/ch04299.

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Our previous report showed that our current benchmark agent, 4-methoxyphenyl p-toluenesulfonate, is a selective antimalarial/anticancer agent. A series of related sulfones and sulfonic acid esters is now examined. 4-Allyloxyphenyl p-toluenesulfonate is a superior antimalarial/anticancer agent. 4-Methoxyphenyl 4-nitrobenzenesulfonate is a superior antimalarial agent, but shows poorer inhibition of human skin cancer cells.

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44

Arias, Mauricio, Ashley L. Hilchie, Evan F. Haney, et al. "Anticancer activities of bovine and human lactoferricin-derived peptides." Biochemistry and Cell Biology 95, no. 1 (2017): 91–98. http://dx.doi.org/10.1139/bcb-2016-0175.

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Lactoferrin (LF) is a mammalian host defense glycoprotein with diverse biological activities. Peptides derived from the cationic region of LF possess cytotoxic activity against cancer cells in vitro and in vivo. Bovine lactoferricin (LFcinB), a peptide derived from bovine LF (bLF), exhibits broad-spectrum anticancer activity, while a similar peptide derived from human LF (hLF) is not as active. In this work, several peptides derived from the N-terminal regions of bLF and hLF were studied for their anticancer activities against leukemia and breast-cancer cells, as well as normal peripheral bloo

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45

Shaji, Neethu, Sandhya M J Nair, and Shaiju S Dharan. "Coumarin Hydrazide: Chemistry, Synthesis and Pharmacological Activities - A Review." International Journal of Research and Review 9, no. 12 (2022): 16–26. http://dx.doi.org/10.52403/ijrr.20221202.

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Coumarins are heterocyclic compound with a benzopyrone structure. Coumarins are a large group of organic compounds found in several plants even in bacteria and fungi. The biological activities of coumarins and its derivatives includes anticoagulant, anticancer, antiulcer, antifungal, anti-HIV, antimicrobial, antiosteoporosis, antioxidant and anti- inflammatory activity. Hydrazide-hydrazone derivatives act as structural sub units in many pharmacologically active compounds including coumarins to give biological activities like antimicrobial, anticancer, antifungal, anti-inflammatory, antiviral,

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46

Ismail, Worood H., Osama H. Abusara, Balqis Ikhmais, Hassan Abul-Futouh, Suhair Sunoqrot, and Ali I. M. Ibrahim. "Design, Synthesis, and Biological Activity of Coniferyl Aldehyde Derivatives as Potential Anticancer and Antioxidant Agents." Jordan Journal of Pharmaceutical Sciences 16, no. 2 (2023): 368–80. http://dx.doi.org/10.35516/jjps.v16i2.1463.

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Natural products are known to exhibit antimicrobial, anticancer, and antioxidant activities. Among these natural products is cinnamon which contains cinnamaldehyde. Cinnamaldehyde and its derivatives have been reported to have anticancer and antioxidant activities. Coniferyl aldehyde, a non-cytotoxic compound and a cinnamaldehyde derivative, has also been shown to have anticancer activity. In this study, several derivatives of coniferyl aldehyde were synthesized and evaluated for their anticancer and antioxidant activities. Compounds 1, 2, 4, and 8-11 showed cytotoxic activity against H1299 ce

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47

Yan, Xiaowei, Maolin Hu, Qian Miao, Shun Wang, and Kejian Zhao. "The Synthesis and Anticancer Activities of Peptide 5-fluorouracil Derivatives." Journal of Chemical Research 2009, no. 4 (2009): 261–64. http://dx.doi.org/10.3184/030823409x431364.

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A new series of peptide 5-fluorouracil derivatives was designed and synthesised in order to test in vitro anticancer activities. The results indicated that peptide 5-fluorouracil derivatives possessed anticancer activities against human HL-60 and Bel-7402 cell lines. The structures of the compounds were determined by means of 1H NMR, 13C NMR, IR, mass spectra and elemental analyses.

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48

Suphachai, Charoensin. "Antioxidant and anticancer activities of Moringa oleifera leaves." Journal of Medicinal Plants Research 8, no. 7 (2014): 318–25. http://dx.doi.org/10.5897/jmpr2013.5353.

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Nadeem, Rana Asif, Muhammad Abdul Qadir, Mahmood Ahmed, and Imran Sajid. "Cephalosporin Conjugated Sulfonamides: Synthesis, Characterization and Anticancer Activities." Letters in Drug Design & Discovery 17, no. 3 (2020): 264–70. http://dx.doi.org/10.2174/1570180815666180820144621.

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Abstract:

Background: In the present study, eight new cephalosporin conjugated sulfonamides were synthesized to investigate the anticancer activity. Methods: All the compounds were characterized on the basis of FTIR, 1HNMR, MS and elemental analysis (CHN). The new compounds were evaluated against the Vero and Hep G2 cancer cell lines for their anticancer activities. Cytotoxicity of all the compounds was determined against brine shrimp at 20 μg concentration. Results and Conclusion: The results revealed that ceftriaxone conjugated sulfonamide was the most potent and showed cytotoxicity (86.4 %) comparabl

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Tabbi, Aouatef, Dahmane Tebbani, Angelamaria Caporale, et al. "New Adamantyl Chalcones: Synthesis, Antimicrobial and Anticancer Activities." Current Topics in Medicinal Chemistry 17, no. 4 (2016): 498–506. http://dx.doi.org/10.2174/1568026616666160824121935.

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