Academic literature on the topic 'And apigenin'

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Journal articles on the topic "And apigenin"

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Shailendra, Boini, and Puligilla Shankaraiah. "Antioxidant and Alpha Amylase Inhibitory Activity of Apigenin in Alloxan Induced Diabetic Rats." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 12 (2024): 125–31. http://dx.doi.org/10.56557/upjoz/2024/v45i124111.

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Purpose: to study the antioxidant, inhibitory activity of alpha amylase, antidiabetic, effects of flavonoid Apigeninin in diabetic rats. Methods: The effect of Apigeninon on blood glucose and antioxidant activities were estimated in alloxan induced diabetic and treated rats. The α-amylase inhibitory activity in the serum was assessed after oral administration of 7thday, 14th day, and 21st days treatment of Apigenin. Results: The Apigenin was reduced the serum glucose, α-amylase levels and increased antioxidant levels significantly (P<0.05) in Apigenin alone and combination with Metformin tr
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Wang, Minqian, Jenni Firrman, LinShu Liu, and Kit Yam. "A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota." BioMed Research International 2019 (October 16, 2019): 1–18. http://dx.doi.org/10.1155/2019/7010467.

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Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities. Published reviews all focused on the findings using eukaryotic cells, animal models, or epidemiological studies covering the pharmacokinetics, cancer chemoprevention, and drug interactions of apigenin; however, no review is available on the antimicrobial effects of apigenin. Research proves that dietary apigenin passes through the upper gastrointestinal tract and reaches the colon after consumption. For that reason, it is worthwhile to study the potential interactions between apigenin and human gut microbiota. This
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Bian, Shichang, Hongjuan Wan, Xinyan Liao, and Weisheng Wang. "Inhibitory Effects of Apigenin on Tumor Carcinogenesis by Altering the Gut Microbiota." Mediators of Inflammation 2020 (October 5, 2020): 1–9. http://dx.doi.org/10.1155/2020/7141970.

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The flavonoid apigenin is common to many plants. Although the responsible mechanisms have yet to be elucidated, apigenin demonstrates tumor suppression in vitro and in vivo. This study uses an azoxymethane (AOM)/dextran sodium sulfate- (DSS-) induced colon cancer mouse model to investigate apigenin’s potential mechanism of action exerted through its effects upon gut microbiota. The size and quantity of tumors were reduced significantly in the apigenin treatment group. Using 16S rRNA high-throughput sequencing of fecal samples, the composition of gut microbiota was significantly affected by api
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Golonko, Aleksandra, Adam Jan Olichwier, Agata Szklaruk, et al. "Apigenin’s Modulation of Doxorubicin Efficacy in Breast Cancer." Molecules 29, no. 11 (2024): 2603. http://dx.doi.org/10.3390/molecules29112603.

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Apigenin, a naturally derived flavonoid, is increasingly being acknowledged for its potential therapeutic applications, especially in oncology. This research explores apigenin’s capacity to modulate cancer cell viability, emphasizing its roles beyond its minimal antioxidant activity attributed to its basic molecular structure devoid of hydroxyl groups. We investigated apigenin’s effects on two breast cancer cell lines, estrogen-dependent MCF-7 and non-estrogen-dependent MDA-MB-231 cells. Our findings reveal that apigenin exerts a dose-dependent cytotoxic and anti-migratory impact on these cell
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Sánchez-Marzo, Pérez-Sánchez, Ruiz-Torres, et al. "Antioxidant and Photoprotective Activity of Apigenin and its Potassium Salt Derivative in Human Keratinocytes and Absorption in Caco-2 Cell Monolayers." International Journal of Molecular Sciences 20, no. 9 (2019): 2148. http://dx.doi.org/10.3390/ijms20092148.

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Ultraviolet (UV) radiation, especially types A (UVA) and B (UVB), is one of the main causes of skin disorders, including photoaging and skin cancer. Ultraviolent radiation causes oxidative stress, inflammation, p53 induction, DNA damage, mutagenesis, and oxidation of various molecules such as lipids and proteins. In recent decades, the use of polyphenols as molecules with an antioxidant and anti-inflammatory capacity has increased. However, some of these compounds are poorly soluble, and information regarding their absorption and bioavailability is scarce. The main objective of this study was
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Lestari, Dwintha, Elin Yulinah Sukandar, and Irda Fidrianny. "IN SILICO STUDY OF APIGENIN AND APIGETRIN AS INHIBITOR OF 3-HYDROXY-3-METHYL-GLUTAYL-COENZYME A REDUCTASE." Asian Journal of Pharmaceutical and Clinical Research 10, no. 11 (2017): 284. http://dx.doi.org/10.22159/ajpcr.2017.v10i11.20493.

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Objective: The objectives of this research were to investigate in silico interaction between apigenin and apigetrin with 3-hydroxy-3-methyl-glutayl-coenzyme A (HMG Co-A) reductase, to find the most favorable binding site as well as to predict the binding mode.Materials and Methods: Docking calculation was performed by branded Sony Vaio PC Linux Ubuntu 14.04 LTS. The binding process based on the best docking result with HMG Co-A reductase was presented in two-dimensional diagram. Statin, atorvastatin, and R-mevalonate were used as standard.Results: Binding affinity and inhibition constant of R-
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Ivanov, Marija, Abhilash Kannan, Dejan S. Stojković, et al. "Flavones, Flavonols, and Glycosylated Derivatives—Impact on Candida albicans Growth and Virulence, Expression of CDR1 and ERG11, Cytotoxicity." Pharmaceuticals 14, no. 1 (2020): 27. http://dx.doi.org/10.3390/ph14010027.

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Due to the high incidence of fungal infections worldwide, there is an increasing demand for the development of novel therapeutic approaches. A wide range of natural products has been extensively studied, with considerable focus on flavonoids. The antifungal capacity of selected flavones (luteolin, apigenin), flavonols (quercetin), and their glycosylated derivatives (quercitrin, isoquercitrin, rutin, and apigetrin) along with their impact on genes encoding efflux pumps (CDR1) and ergosterol biosynthesis enzyme (ERG11) has been the subject of this study. Cytotoxicity of flavonoids towards primar
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Charrière, Karine, Vincent Schneider, Manon Perrignon-Sommet, et al. "Exploring the Role of Apigenin in Neuroinflammation: Insights and Implications." International Journal of Molecular Sciences 25, no. 9 (2024): 5041. http://dx.doi.org/10.3390/ijms25095041.

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Neuroinflammation, a hallmark of various central nervous system disorders, is often associated with oxidative stress and neuronal or oligodendrocyte cell death. It is therefore very interesting to target neuroinflammation pharmacologically. One therapeutic option is the use of nutraceuticals, particularly apigenin. Apigenin is present in plants: vegetables (parsley, celery, onions), fruits (oranges), herbs (chamomile, thyme, oregano, basil), and some beverages (tea, beer, and wine). This review explores the potential of apigenin as an anti-inflammatory agent across diverse neurological conditi
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He, Xiangfei, Yibo Wen, Qingwei Wang та ін. "Apigenin Nanoparticle Attenuates Renal Ischemia/Reperfusion Inflammatory Injury by Regulation of miR-140-5p/CXCL12/NF-κB Signaling Pathway". Journal of Biomedical Nanotechnology 17, № 1 (2021): 64–77. http://dx.doi.org/10.1166/jbn.2021.3010.

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Apigenin as a natural flavonoid product has been proved previously to play a renoprotective effect during ischemia/reperfusion injury (IRI), but the particular mechanisms involving the positive effects of apigenin remain totally unclear. The study investigated apigenin's roles and underlying biological mechanisms in IR-induced acute kidney injury (AKI). Thirty-six mice received a right nephrectomy and clamping of the left renal artery for 30 minutes, and then perfusion for 24 h. Apigenin was loaded onto a biodegradable polymer carrier (nanoparticle) to enhance its bioavailability. Mice were su
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Abid, Rameesha, Shakira Ghazanfar, Arshad Farid, et al. "Pharmacological Properties of 4′, 5, 7-Trihydroxyflavone (Apigenin) and Its Impact on Cell Signaling Pathways." Molecules 27, no. 13 (2022): 4304. http://dx.doi.org/10.3390/molecules27134304.

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Plant bioactive compounds, particularly apigenin, have therapeutic potential and functional activities that aid in the prevention of infectious diseases in many mammalian bodies and promote tumor growth inhibition. Apigenin is a flavonoid with low toxicities and numerous bioactive properties due to which it has been considered as a traditional medicine for decades. Apigenin shows synergistic effects in combined treatment with sorafenib in the HepG2 human cell line (HCC) in less time and statistically reduces the viability of tumor cells, migration, gene expression and apoptosis. The combinatio
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Dissertations / Theses on the topic "And apigenin"

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Freitas, Luciana da Silva. "Desenvolvimento, estabilidade e eficácia de formulações fotoprotetoras contendo extrato de Matricaria chamomilla e seus componentes isolados." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/60/60137/tde-20042011-210250/.

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As propriedades dos extratos vegetais vêm sendo cada vez mais investigadas, suscitando o interesse em aliar o potencial destes para minimizar efeitos do fotoenvelhecimento da pele decorrentes da ação dos radicais livres à fotoproteção proporcionada pelos filtros solares. Apesar do uso difundido de vários extratos vegetais, alguns deles, como a Matricaria chamomilla, ainda carecem de estudos acerca de suas propriedades e efeitos biológicos na pele, especialmente quando este é veiculado em formulações dermocosméticas. Assim, esse trabalho teve por objetivo a avaliação da estabilidade e da eficác
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Arango, Tamayo Daniel Alejandro. "The Immune-modulatory and Anti-carcinogenic Mechanisms of the Flavonoid Apigenin." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1437511798.

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Leonardi, Tety. "Dietary apigenin and naringenin protect against colon carcinogenesis by lowering high multiplicity aberrant crypt foci and enhancing apoptosis in azoxymethane-treated rats." Texas A&M University, 2003. http://hdl.handle.net/1969.1/3948.

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Colon cancer is the third most common cancer in the United States. However, evidence indicates that a proper diet abundant in fruits and vegetables may be protective against colon cancer development. Bioactive compounds in fruits and vegetables, such as flavonoids and limonoids, have been shown to possess anti-proliferative and antitumorigenic effects in various in vitro and in vivo models of cancer. Since there are few animal studies involving flavonoids and limonoids and colon cancer, this experiment investigated the potentially protective effects of four citrus flavonoids and one limonoid m
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Nóbrega, Ananda de Toledo. "Desenvolvimento e avaliação da eficácia de formulações cosméticas contendo extrato de camomila ou seus componentes isolados." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/60/60137/tde-25112010-154838/.

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Os extratos vegetais, em função de sua rica composição e propriedades medicinais têm tido grande interesse na área cosmética. Contudo, muitas vezes, o grande número de componentes químicos pode causar instabilidade às formulações, assim, a indústria cosmética também utiliza seus principais componentes isolados. Dentre esses extratos podemos destacar o de camomila, o qual vem sendo comumente utilizado em cosméticos. Este possui uma rica composição de flavonóides, terpenos, polissacarídeos, dentre outros, o que lhe confere propriedades anti-inflamatória, antioxidante e emoliente, as quais foram
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Nicholas, Courtney. "The Anti-Inflammatory Mechanisms of the Flavonoid Apigenin In Vitro and In Vivo." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1259783472.

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Santos, Francielly Torres dos. "Parâmetros químicos e qualidade de salsa em função de substratos orgânicos associados ao biochar." Universidade Estadual do Oeste do Parana, 2016. http://tede.unioeste.br:8080/tede/handle/tede/271.

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Made available in DSpace on 2017-05-12T14:47:40Z (GMT). No. of bitstreams: 1 Tese Francielly_ Torres dos Santos.pdf: 2692597 bytes, checksum: db1b8713e9d8a55de139153f5a86a29e (MD5) Previous issue date: 2016-02-16<br>Parsley has been widely traded as a flavoring in Brazil and worldwide. The quality to produce salsa depends on its cropping management. This, this study aimed to evaluate the effect of alternative organic substrates in productivity and nutritional quality of Petroselium crispum. The treatments consisted of five organic compounds obtained by agro-industrial waste composting proces
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Bailey, Caleb Michael. "Expounding Maspin and IRF6 characterization of a novel serpin partnership /." Diss., University of Iowa, 2006. http://ir.uiowa.edu/etd/52.

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Slobodan, Gigov. "Uticaj apigenina i natrijum-deoksiholata na biološku raspoloživost raloksifena." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2017. http://www.cris.uns.ac.rs/record.jsf?recordId=104332&source=NDLTD&language=en.

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Raloksifen je predstavnik selektivnih modulatora estrogenih receptora koji se koristi u terapiji osteoporoze i invazivnog oblika raka dojke u postmenopauzi. Raloksifen se relativno dobro resorbuje iz gastrointestinalnog trakta, ali pri prvom prolasku kroz jetru podleže biotransformaciji u značajnom procentu, &scaron;to je uzrok njegove niske biolo&scaron;ke raspoloživosti. Bioraspoloživost kod ljudi iznosi 2%, a kod Wistar pacova 39%. Različite supstance se koriste da bi se pobolj&scaron;ala bioraspoloživost lekova. Žučne kiseline, kao &scaron;to je deoksiholna kiselina, omogućavaju bolji prol
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Zuo, Huaxin [Verfasser]. "Tanshinone IIA and Apigenin as potential and natural inhibitors of the metastatic activities of uveal melanoma cells / Huaxin Zuo." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2019. http://d-nb.info/1179506723/34.

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Nelson, Nadine D. "Ikaros Deficiency Leads To An Imbalance in Effector and Regulatory T Cell Homeostasis in Murine Pancreatic Cancer." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5810.

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Pancreatic cancer is one of the deadliest cancers with a five-year survival rate of 6%. Pancreatic cancer is resistant to conventional chemotherapy and is usually diagnosed at late stages. Current treatment options have minimal effects in extending patients' lives beyond 10 months. One significant limitation in developing treatments to combat pancreatic cancer is its immunosuppressive microenvironment. Pancreatic cancer secretes factors that activate immunosuppressive cells, such as regulatory T cells (Tregs). These Tregs suppress effector CD4+ and CD8+ T cell anti-tumor immune responses. Ther
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Books on the topic "And apigenin"

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Vogelsang-Tschiersch, Katharina. Apigenin, Apigenin-7-Glucosid und Acylderivate Aus Matucaria Recutita L. Gebruder Borntraeger Verlagsbuchhandlung, Science Publishers, 1994.

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Torkin, Risa. The anti-tumour effects of apigenin in neuroblastoma. 2005.

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Stacks, Nilus M. Apigenin and Naringenin: Natural Sources, Pharmacology and Role in Cancer Prevention. Nova Science Publishers, Incorporated, 2015.

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Book chapters on the topic "And apigenin"

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Rashid, Summya. "Chemoprevention by Apigenin." In Cancer and Chemoprevention: An Overview. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-2579-2_18.

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Schomburg, Dietmar, and Dörte Stephan. "Apigenin 4′-O-methyltransferase." In Enzyme Handbook 11. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61030-1_72.

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Aprotosoaie, Ana Clara, and Anca Miron. "Apigenin: Chemistry and Pharmacology." In Handbook of Dietary Flavonoids. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-030-94753-8_2-1.

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Ahmad, Asif, and Khunsha Younas. "Microbial Production of Apigenin and Chrysin." In Microbial Production of Food Bioactive Compounds. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-030-81403-8_17-1.

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Mukherjee, Biswajit, Soumyabrata Banerjee, Laboni Mondal, Shreyasi Chakraborty, Deepayan Chanda, and Jayawardane Athukorallage Chamindik Perera. "Bioactive Flavonoid Apigenin and Its Nanoformulations: A Promising Hope for Diabetes and Cancer." In Nanomedicine for Bioactives. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-1664-1_13.

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Sharma, Aksh, and Surbhi. "Apigenin, Catechins and Soy Isoflavones as a Natural Treatment for Polycystic Ovarian Syndrome." In Herbal Medicine Applications for Polycystic Ovarian Syndrome. CRC Press, 2023. http://dx.doi.org/10.1201/9781003344728-10.

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"Apigenin." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_1026.

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Cvetanović, Aleksandra. "Apigenin." In A Centum of Valuable Plant Bioactives. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-822923-1.00024-8.

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"Apigenin (5,7,4′-Trihydroxyflavone)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_262.

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"Apigenin 7-O-glucuronide." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_378.

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Conference papers on the topic "And apigenin"

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Okano, Kazunori, Naomi Tanga, Rieko Aida, et al. "Utilizing Near-Infrared Femtosecond Laser-Generated Gas Bubbles for Acellular Area Construction in Cell Monolayers." In JSAP-Optica Joint Symposia. Optica Publishing Group, 2024. https://doi.org/10.1364/jsapo.2024.17a_a31_3.

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The focused irradiation of near-infrared femtosecond laser (NIR fs laser) pulses in biological solvents efficiently induces molecular breakdown, generating vaporous gas micro bubbles [1]. Such irradiation on live cells induces apoptosis and necrosis depending in pulse energy [2]. Here we examined the relation bubble size and numbers and pulse energy in cells. Further, the NIR fs laser bubbling-formed cell-removed acellular area was used for assaying antimotility effects of the plant flavonoid apigenin.
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Ivanov, Marija, Ana Ćirić, Jasmina Glamočlija, et al. "Apigenin: Antifungal activity of flavonoid commonly found in beer and wine." In VII naučno-stručni simpozijum sa međunarodnim učešćem "Pivo, pivarske sirovine i tržište". Institute of Field and Vegetable Crops Research, Novi Sad, 2024. https://doi.org/10.5937/pivos24019i.

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Flavonoids are bioactive compounds present in various plants, and some of them, such as apigenin, are also found in beverages including beer and wine. Apigenin is known for various biological activities, such as anti-inflammatory and antioxidant, and the goal of our research was to gain a more detailed insight into its antifungal potential. Using the microdilution method, the minimum inhibitory (MIC) and minimum fungicidal concentrations (MFC) of apigenin against different species of the Candida were determined and ranged from 0.10 to 0.15 mg/mL for MIC and 0.15-0.30 mg/mL for MFC. In addition
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Karpiński, Tomasz, Artur Adamczak, and Marcin Ożarowski. "Antibacterial activity of apigenin, luteolin, and their C-glucosides." In 5th International Electronic Conference on Medicinal Chemistry. MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06321.

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Сурбеева, Е. С., И. И. Тернинко, Ю. Э. Генералова, and С. И. Комова. "COMPARATIVE DETERMINATION OF APIGENIN IN DIFFERENT VARIETIES OF LEAF CELERY." In Современные тенденции развития технологий здоровьсбережения. Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт лекарственных и ароматических растений", 2021. http://dx.doi.org/10.52101/9785870191027_2021_389.

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Praveena, R., K. Anbazhakan, and K. Sadasivam. "Local orbital locator analysis of isomeric compounds of luteolin and apigenin." In ADVANCES IN BASIC SCIENCE (ICABS 2019). AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5122633.

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Sharma, Haripaul, and Sanjay Gupta. "Abstract 4632: Sub-cellular distribution and antioxidant potential of plant flavonoid apigenin." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4632.

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Shukla, Sanjeev, Ata Abbas, and Sanjay Gupta. "Abstract 4649: Apigenin increases maspin expression and suppresses invasiveness in prostate cancer cells." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4649.

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Blay, J., J. Fux, V. Bentley, B. Diaconu, and E. Lefort. "Actions of the Dietary Flavone Apigenin in the Context of Human Colorectal Cancer." In Abstracts of the NHPRS – The 15th Annual Meeting of the Natural Health Products Research Society of Canada (NHPRS). Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1644924.

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Shukla, Sanjeev, Manish Datt, Mark R. Chance, and Sanjay Gupta. "Abstract 3660: Apigenin suppresses IKK activation and downstream signaling leading to prostate cancer inhibition." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3660.

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Tong, Xin, Bryan B. Bridgeman, Salida Mirzoeva, Susan E. Crawford, Olga V. Volpert, and Jill C. Pelling. "Abstract 5075: Targeting TSP1 and inhibiting angiogenesis in UV-induced skin cancer by apigenin." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-5075.

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Reports on the topic "And apigenin"

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Olasehinde, Tosin, and Oyiinlola Olaokun. The beneficial role of apigenin against cognitive dysfunction and neurobehavioural deficit: A Protocol of Systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.12.0010.

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