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Rehman, Ansa Kulsoom, Humaira Taj Niazi, and Laila Bahadur. "Hematological Indicators Assessing Severity in Dengue Patients." Pakistan Journal of Medical and Health Sciences 16, no. 11 (2022): 451–53. http://dx.doi.org/10.53350/pjmhs20221611451.
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Background: Dengue is viral disease of human transmitted by Aedes aegypti mosquito. The clinical signs and symptoms of dengue infection range significantly, from mild dengue fever to a severe illness. Objective: Our study aims to describe the potential predictive hematological parameters which are associated with severity in dengue patients. Methodology: This study was descriptive study conducted at the department of Pathology (Hematology), Maqsood Medical Complex and General Hospital, Peshawar, for duration of six months from 1st May 2022 to 31st October 2022. Blood samples were taken aseptically from all the included patients and were sent to the hospital diagnostic laboratory where the hematological parameters were determined. All the data was collected in a pre-designed proforma. The data analysis was done by using IBM SPSS version 23. Results: In the current study, a total of 160 patients were enrolled. There were 102 (63.75%) male patients while female patients were 56 (36.25%). Based on the hematological parameters, the mean (±SD) Hematocrit (%), Hemoglobin (g/dl), White cell count (/µL), Lymphocytes(/µL), Neutrophils (%) and Platelets (/µL) in non severe dengue cases vs severe dengue cases were 39.2 (±5.1)% vs 42.3 (±4.3)%, 12.5 (±0.9) g/dl vs 13.9 (±1.8) g/dl, 3290 (±1.4) /µL vs 4750 (±1.6) /µL, 40.6 (±12.19)/µL vs 46.1 (±9.96) /µL, 44.4 (±16.56)% vs 49.4 (±12.44) % and 10,5000 (±1.12) /µL vs 56,000 (±2.36)/µL respectively. Conclusion: Our study concludes that some common hematological markers have a substantial correlation with the severity of dengue illness. Keywords: Hematological indicators; severe dengue; Non-severe dengue
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Umanska, Anna, Dmytro Melnichuk, and Lilia Kalachnyuk. "Hematological indicators of rats for artificial hypobiosis." ScienceRise: Biological Science, no. 6 (9) (December 31, 2017): 7–9. http://dx.doi.org/10.15587/2519-8025.2017.118786.
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Kachenkova, Ekaterina Sergeevna, Yulia Vladimirovna Zbrueva, Elena Sergeevna Tkacheva, et al. "Hematological Indicators of Students Who Started Races." Journal Of Biochemical Technology 13, no. 1 (2022): 7–12. http://dx.doi.org/10.51847/noiozxvk5j.
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Karusheva, K. Y., V. A. ,. Konoplev, and S. P. Kovalev. "Clinical-hematological indicators of dogs under stress." Veterinaria i kormlenie, no. 1 (February 2019): 44–46. http://dx.doi.org/10.30917/att-vk-1814-9588-2019-1-14.
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Pylypenko, A. V. "Prognostic value of hematological indicators in preeclampsia." Reproductive health of woman, no. 5 (July 31, 2024): 60–65. http://dx.doi.org/10.30841/2708-8731.5.2024.310396.
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The objective: to evaluate the changes in hematological indicators as early predictors of the development of preeclampsia.Materials and methods. A retrospective cohort study was conducted with the participation of 49 pregnant women in the period from March 2020 to January 2022. All women were observed in the women’s consultation of the private medical center “Leleka”.Pregnant women were divided into two groups: the main group – women who were diagnosed with preeclampsia at >20 weeks of pregnancy, n=20), and the control group (n=29) – women without preeclampsia during pregnancy.Each woman underwent a general blood test, the systemic inflammatory response index (SIRI), allergy index (AI), immunoreactivity index (II), adaptation index (А) in I (up to 12 weeks), II (13–27 weeks) and III (from 28 weeks) trimesters of pregnancy, respectively, were calculated.Results. Pregnant women, in whom subsequently preeclampsia developed, had statistically significant differences in white blood cell count and erythrocyte sedimentation rate (ESR) compared to controls.The AI index decreased statistically significantly in the control group in the II trimester compared to the I trimester (р=0.05), while the changes in the main group were statistically insignificant. The median AI indicator in the main group decreases by 22.7% in the II trimester, and increases by 8.9% in the III trimester; in the control group the median AI decreases by 12.3% and 7.5%, respectively.The median adaptation index in the main group statistically significantly decreases by 25.7% in the II trimester and increases by 19.2% in the III trimester. In the control group, this index does not increase in the III trimester.Conclusions. The dynamics of the main hematological indicators and calculated indices can be useful for predicting of preeclampsia development. Carrying out a general blood test as a widely available method is possible in order to stratify the individual risk of preeclampsia development in combination with other generally accepted factors of this complication.High values of leukocytes and ESR in the early terms of pregnancy in women who subsequently developed preeclampsia confirm the role of inflammation as an etiopathogenetic factor. A change in the integral hematological indices of allergy and adaptation can be an early predictor of preeclampsia.The results of this study predict the presence of preeclampsia clusters, the determination of the mechanisms of which will allow to expand the possibilities of preventive measures, which needs to be confirmed in large-scale randomized studies in the future.
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V.I., Eremenko, and Rotmistrovskaya E.G. "HEMATOLOGICAL INDICATORS IN HEIFERS OF DIFFERENT BREEDS." Bulletin of Agrarian Science 4, no. 103 (2023): 78–81. http://dx.doi.org/10.17238/issn2587-666x.2023.4.78.
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A.V., Pylypenko. "Prognostic value of hematological indicators in preeclampsia." Reproductive Health of Woman, no. 5 (July 31, 2024): 60–65. https://doi.org/10.30841/2708-8731.5.2024.310396.
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<strong>The objective</strong>: to evaluate the changes in hematological indicators as early predictors of the development of preeclampsia.<strong>Materials and methods</strong>. A retrospective cohort study was conducted with the participation of 49 pregnant women in the period from March 2020 to January 2022. All women were observed in the women’s consultation of the private medical center “Leleka”.Pregnant women were divided into two groups: the main group – women who were diagnosed with preeclampsia at >20 weeks of pregnancy, n=20), and the control group (n=29) – women without preeclampsia during pregnancy.Each woman underwent a general blood test, the systemic inflammatory response index (SIRI), allergy index (AI), immunoreactivity index (II), adaptation index (А) in I (up to 12 weeks), II (13–27 weeks) and III (from 28 weeks) trimesters of pregnancy, respectively, were calculated.<strong>Results</strong>. Pregnant women, in whom subsequently preeclampsia developed, had statistically significant differences in white blood cell count and erythrocyte sedimentation rate (ESR) compared to controls.The AI index decreased statistically significantly in the control group in the II trimester compared to the I trimester (р=0.05), while the changes in the main group were statistically insignificant. The median AI indicator in the main group decreases by 22.7% in the II trimester, and increases by 8.9% in the III trimester; in the control group the median AI decreases by 12.3% and 7.5%, respectively.The median adaptation index in the main group statistically significantly decreases by 25.7% in the II trimester and increases by 19.2% in the III trimester. In the control group, this index does not increase in the III trimester.<strong>Conclusions</strong>. The dynamics of the main hematological indicators and calculated indices can be useful for predicting of preeclampsia development. Carrying out a general blood test as a widely available method is possible in order to stratify the individual risk of preeclampsia development in combination with other generally accepted factors of this complication.High values of leukocytes and ESR in the early terms of pregnancy in women who subsequently developed preeclampsia confirm the role of inflammation as an etiopathogenetic factor. A change in the integral hematological indices of allergy and adaptation can be an early predictor of preeclampsia.The results of this study predict the presence of preeclampsia clusters, the determination of the mechanisms of which will allow to expand the possibilities of preventive measures, which needs to be confirmed in large-scale randomized studies in the future.
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Huang, Yang-Yu, Xuan Liu, Shen-Hua Liang, Yu Hu, and Guo-Wei Ma. "The Prognostic Value of Preoperative Serum D-dimer Levels After Surgical Resection of Thymic Epithelial Tumors." Cancer Control 29 (January 2022): 107327482211291. http://dx.doi.org/10.1177/10732748221129108.
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Introduction Thymic epithelial tumors are the most common mediastinal tumors. Despite the high survival rate after surgery, some patients still require postoperative adjuvant therapy and closer follow-up. Hematological indicators such as biochemical routines and coagulation indicators have been reported to be independently associated with the prognosis of various malignancies. Therefore, we included hematological indicators in the analysis. Methods The data of 105 patients with thymic epithelial tumors were retrospectively collected from Sun Yat-sen University Cancer Center, and the patients with missing preoperative hematological indicators were excluded. X-tile software was used to obtain the best cutoff value of each preoperative hematological indicator, and COX regression analysis and Kaplan-Meier survival curves were used to demonstrate statistically significant results. Results COX univariate regression analysis of all patients showed that Masaoka stage, T stage, WHO histologic types, D-dimer, albumin-fibrinogen ratio (AFR), Fibrinogen (Fbg) were associated with postoperative overall survival ( P < .05). T stage, WHO histologic types, D-dimer, and AFR were associated with postoperative recurrence-free survival ( P < .05). Finally, multivariate regression analysis showed that T stage, D-dimer levels were independently associated with postoperative overall survival (OS) and recurrence-free survival (RFS) in patients with thymic epithelial tumors. Conclusions For thymic epithelial tumors, higher preoperative D-dimer levels predict poorer survival and shorter recurrence-free survival. This may help guide postoperative adjuvant therapy and follow-up patterns in patients with thymic epithelial tumors.
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Karpenko, L. Yu, P. A. Polistovskaya, A. I. Enukashvili, and A. B. Balykina. "Influence of cadmium on hematological indicators of carp." International bulletin of Veterinary Medicine 1 (2020): 92–96. http://dx.doi.org/10.17238/issn2072-2419.2020.1.92.
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The article is devoted to the assessment of the toxic effects of cadmium acetate on fish. The research topic is relevant, since heavy metals, and especially cadmium, are ones of the most dangerous pollutants for the aquatic environment. After the emission of the already used water by the electricity-power plants into the reservoirs of circulating wa-ter, a sharp increase in the maximum permit-ted concentrations of heavy substances can be observed often, which act on hydrobi-onts for a rather short period of time. That is why, modeling this effect is necessary to study the effects of heavy metals. The aim of the assay was to study the hematological parameters of carp after exposure to various concentrations of cadmium acetate. During the experiment, 5 groups of fish were formed - 1 control group (10 fish), 4 experimental groups - 10 fish each. The experimental groups of fish were exposed in a solution of cadmium acetate (Cd (CH3COO) 2) with concentrations of 0.05 mg / l, 0.5 mg / l, 5 mg / l, 50 mg / l (exceeding the maximum permissible concentration of cadmium for fisheries in 10, 100, 1000 and 10000 times respectively). We have investigated: the erythrocyte sedimentation rate, the number of red blood cells in the blood and the con-centration of hemoglobin in the blood. Dur-ing the study, the authors noted an increase in the erythrocyte sedimentation rate due to the formation of conglomerates of blood cells with plasma proteins, as well as a de-crease in the number of red blood cells due to the toxic effect of cadmium acetate. A decrease in the concentration of hemoglobin in the blood was also observed, probably associated with a decrease in the number of red blood cells due to their lysis. With an increase in the concentration of the metal under study, there is a significant increase in ESR, a decrease in the level of hemoglobin and the number of red blood cells.
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Marshall, Heather, Lyndsay Field, Achankeng Afiadata, Chugey Sepulveda, Gregory Skomal, and Diego Bernal. "Hematological indicators of stress in longline-captured sharks." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 162, no. 2 (2012): 121–29. http://dx.doi.org/10.1016/j.cbpa.2012.02.008.
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Shevchyk, L.O., N.Ya. Kravets, and I.M. Grod. "The effect of stress on the hematological indicators of rats Rattus norvegicus f. domesticus in the conditions of the biological experiment." Medicni perspektivi 26, no. 1 (2021): 69–77. https://doi.org/10.26641/2307-0404.2021.1.227735.
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The purpose of the work was the need to study the change in weight and hematological indicators of the rats as a reaction-response to being in difficult and unfavorable experimental conditions. The biological experiment was conducted in compliance with the normative conditions of keeping the rats, in accordance with ethical standards and recommendations for humanization of work with laboratory animals. In order to accomplish these tasks, rats were divided into two groups: control rats were housed in a spacious cage with comfortable living conditions and experimental animals were housed in a small cage with limited ability to move freely. For the purity of the experiment, the feed ration of animals of two groups was the same. Weight and hematological indicators were determined by conventional methods in physiology. It has been found that improper housing conditions, causing a stressful situation adversely affect the eating activity of the test animals, which explains the weak correlation of the dynamics of the weight of the animals in the control and experimental groups. The analysis of the absolute mass of the internal organs of rats showed their direct dependence on body weight and the correlation of these parameters between animals of both groups. The study found that the quantitative ratios of the main hematological parameters of each of the rodents are strictly different. The tendency to increase of the investigated parameters in the experimental group in comparison with the control one is symptomatic and can be explained by sympathetic-vegetative influences. The amount of hemoglobin is directly correlated with the number of red blood cells. Comparison of the content of hemoglobin, erythrocytes, leukocytes with body weight showed inversely proportional relationship between them. The persistent predominance of leukocytes in the blood of rats in both groups is likely to genetically determined.
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Dychok-Niedzielska, A. Z., and Y. V. Lesyk. "Influence of sulfur complex on hematological indicators of the rabits." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 20, no. 92 (2018): 203–8. http://dx.doi.org/10.32718/nvlvet9242.
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The article presents results on the influence of different amounts of sulfur citrate, manufactured using nanotechnology and sodium sulfate in rabbit diet from 60 to 118 days of age on the hematological parameters of their organism. Studies have been conducted on 30 rabbits of the Hyla hybrid divided into six groups (control and five experimental), 6 animals in each. Animals were kept in regulated microclimate and illumination in mesh cages of 50×120×30 cm. Controlled rabbits fed without restriction a balanced granulated feed with free access to water. The young of the first (E-II), the second (E-II), the third (E-III) and the fourth (E-IV) experimental groups feed the diet of the control group and, during the day, dispensed sulfur citrate from the calculation of 2; 4; 8 and 12 mg S/kg body weight. Rabbits (E-V) of the experimental group fed the diet of the control group and set water with sodium sulfate (Na2SO4) in the amount of 40 mg S/kg body weight. In the preparatory period – 60 days and in the experimental period – at 91 and 118 days of life (31 and 58 days of delivery of supplements), blood samples were collected from the regional anterior vein of rabbits for hematological studies performed using an automatic hematologic analyzer (Orphee Mythic-18, Switzerland). Researches have shown that the administration of citrate sulfur in the amount of 8 mg S/kg of body weight was marked by a greater number of red blood cells and leukocytes, respectively, by 13.4 and 23.3% (P < 0.05) and with a higher level of HCT at 16.2% (P < 0.05), MCH, RDV and MCHC, respectively, 11.1; 14.5 and 2.6% (P < 0.05) on day 58 of the experiment compared with the control group. In the blood of animals in the 2nd experimental group, a higher concentration of hemoglobin (Р < 0.05) was observed at 31 days and a higher HCT (Р < 0.05) level was 58 days compared to control. Thus, the results of the study of the hematological parameters of the body of rabbits indicate their positive changes in the actions of the physiologically substantiated amount of organic sulfur, which contributed to the activation of metabolic processes.
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Shokan, Aksholpan Kanatkyzy, Islana Beibitkyzy Ginayatova, Diana Maratkyzy Yergozova, Natalya Olegovna Kudrina, and Korbozova Nazym Kurmanbaevna. "Effects of Rumex tianschanicus Losinsk extract on hematological indicators in experimental gastritis." Bulletin of the Karaganda University. “Biology, medicine, geography Series” 103, no. 3 (2021): 150–56. http://dx.doi.org/10.31489/2021bmg3/150-156.
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Gastritis is the most common gastrointestinal disease, with peptic ulcer disease accounting for 30 % of all cases, affecting about 10 % of the global population. According to 2020 statistics, 50,8 % of the population in developing countries suffers from gastritis and this number increasing annually. This study examined the medical effects of Rumex tianschanicus root extract on aspirin induced gastritis in rats. Forty five rats, 250±50 g were grouped into two: control group rats received placebo and experimental groups received acetylsalicylic acid 160 mg/kg, orally once daily for 5 consecutive days to induce acute experimental gastritis. Following gastritis registration, rats were grouped into three groups and treated with Rumex tianschanicus L.extract. The first group was given 100 mg/kg orally once a day for ten days. The second group received 50 mg/kg orally once a day for ten days. The third group did not receive the medication. At the end of the study, all the animals were Killed to determine cytological, histological changes and hematological indices. The result showed statistically significant differences (p ≤ 0,001) of total number of leukocytes, total number of erythrocytes, hemoglobin level and content of platelets but they were all within the physiological norm. As a result of the study the Rumex tianschanicus extract pharmacological properties were evaluated and its potential effect on the hematological parameters of rats during the treatment of experimental gastritis accessed. It was discovered that the Rumex tianschanicus extract has no pathological effect on peripheral blood and hemopoiesis during the period of its use. In this regard, the extract of Rumex tianschanicus is recommended for further in-depth research in experimental conditions, followed by a transition to clinical trials.
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Kozar, V. V., I. V. Novikova, A. V. Kulakova, R. F. Yeromenko, O. V. Dolzhykova, and N. M. Brechka. "Hematological Indicators in Patients with Crisis Ischemic Heart Disease." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 7, no. 1 (2022): 112–18. http://dx.doi.org/10.26693/jmbs07.01.112.
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The purpose of the study was to investigate and evaluate the data of hematological studies in women and men with ischemic heart disease in critical condition. Materials and methods. The results of examination of 14 patients with ischemic heart disease in critical condition, who will be hospitalized for approximately the same period of time in the intensive care unit of the cardiology department of the Municipal Non-Profit Enterprise of Kharkiv City Council "Regional Clinical Hospital" were included in the study. The patients included 7 women and 7 men aged 38 to 60 years who were diagnosed with acute myocardial infarction at the clinic. Laboratory tests were performed at the time of hospitalization and after 3–4 consecutive days in the dynamics of treatment. Morphological evaluation of blood cells in a blood smear and quantitative indicators were included in hematological examination and were determined on a hematological analyzer ABX MICROS 60 OT (France). Results and discussion. The study found that women had an increase in white blood cell count, hemoglobin concentration an average and mean erythrocyte hemoglobin increases at the time of hospitalization. Increase in the number of leukocytes, decrease in hemoglobin and erythrocytes were found in men. On the dynamics of treatment for 3–4 days, the number of leukocytes in women decreased by almost 1.4 times compared to the data time of hospitalization, while in men — only by 1.02 time, 4 out of 7 men even had an increase in leukocytes. The number of erythrocytes, the concentration of hemoglobin in females has changed a lot, and the MCN indicator has dropped to the same level. The number of erythrocytes and hemoglobin concentration almost did not change in men. Conclusion. In women and men with ischemic heart disease in a critical condition some differences in hematological parameters were noted. It must be taken into account based on the principles of 4P therapy. Inflammation, according to leukocytosis, was higher in women at the time of hospitalization, but after treatment the reduction was more significant than in men. The numbers of erythrocytes, hemoglobin concentration, erythrocyte index of mean erythrocyte hemoglobin were slightly higher in women than in men. These indicators were mostly reduced in men. Received results show that an increase in procoagulant status was more characteristic for women, and the development of an anemic state was more typical for men. On days 3–4, complete recovery of hematological parameters have not yet occurred, the exception was a slight decrease in the number of leukocytes. This indicates a decrease in the intensity of inflammation. Prospects of further researches. The obtained results of hematological studies of critically condition of patients with ischemic heart disease confirm the importance of laboratory tests for the timely identification of the risk of complications and monitoring the state and prognosis of the disease in men and women
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Bhojani, Priya Laljibhai. "Dengue virus: Investigate serological and hematological indicators for predictions." Indian Journal of Pathology and Oncology 11, no. 4 (2024): 371–76. https://doi.org/10.18231/j.ijpo.2024.080.
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Timely and accurate diagnosis of dengue fever is essential for both efficient treatment and prevention of severe symptoms. Investigating hematological and serological markers for dengue virus infection is the goal of the current investigation. : A laboratory-based cross-sectional study was carried out among patients who visited SVP Hospital in Ahmedabad, Gujarat, between January 2022 and December 2023. Hematological parameters were assessed and blood samples from suspected dengue cases were analyzed using the rapid diagnostic immunochromatography (ICT) approach. Continuous variables were compared between groups infected with dengue and those that were not using the Mann-Whitney U test. A binary logistic regression analysis was performed to evaluate the correlation between dengue positive and other factors. Dengue-positive participants showed low mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC), thrombocytopenia, leucopenia, erythrocytosis, and high hemoconcentration in comparison to dengue-negative people. On the other hand, dengue positivity was significantly predicted by platelet count, total leucocyte count, MCH, MCHC, neutrophil count, and lymphocyte count, according to binary logistic regression. : The features and demographics of dengue-positive cases were determined in this investigation, along with their associations with hematological markers. Moreover, by helping medical professionals diagnose and treat dengue patients faster, the discovered predictive indicators can lessen the disease's effects.
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Zhelankin, R. V., and G. I. Pronina. "Hematological indicators of the marsh frog during stimulated spawning." Timiryazev Biological Journal 2, no. 2 (2024): 69–74. http://dx.doi.org/10.26897/2949-4710-2024-2-2-69-74.
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When breeding frogs on a farm, it is necessary to monitor their health status, and the most convenient method of control is a blood test. Hematological parameters of marsh frogs were studied before and after spawning. After hibernation at a temperature of 4°C from the first week in the pool, the frogs were subjected to hormonal stimulation with a mixture of drugs “Gonadotropin chorionic” and “Surfagon”, the next day successful spawning with 100% fertilization of eggs was observed. A reduced number of red blood cells was found in the blood of frogs after spawning. The proportion of neutrophils and eosinophils in the leukogram of frogs after spawning decreased, the number of monocytes increased 3 times, the proportion of basophils increased. The stimulated spawning of the marsh frog was reproduced for the first time in captivity under the control of an analysis of hematological parameters, which showed the possibility of using this process in raniculture conditions.
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Gilmutdinov, R. Ya, A. V. Malev, and G. G. Shalamova. "HEMATOLOGICAL INDICATORS OF LARGE WILD REPRESENTATIVES OF CAT FAMILIES." Scientific Notes Kazan Bauman State Academy of Veterinary Medicine 239, no. 3 (2019): 76–80. http://dx.doi.org/10.31588/2413-4201-1883-239-3-76-80.
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Voronkova, O. S., O. O. Pavlova, O. M. Starishko, O. M. Prykhodko, A. V. Narbiekova, and O. M. Simonova. "CHANGES IN HEMATOLOGICAL INDICATORS IN PATIENTS WITH CORONAVIRUS DISEASE." Bulletin of Problems Biology and Medicine 1, no. 1 (2023): 120. http://dx.doi.org/10.29254/2077-4214-2023-1-168-120-130.
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Ibrahim, Mohammed Aldeailej, Talat Jameel Daniyah, Mohammed N. Alosaimi Naif, et al. "Vitamin D and Hematological Indicators of Inflammation in Prediabetes." International Journal of Medical Science and Clinical Research Studies 03, no. 10 (2023): 2437–44. https://doi.org/10.5281/zenodo.10255189.
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<strong>Objectives:</strong> Prediabetes is characterized by the presence of inflammation. Hematological parameters provide the advantageous qualities of being cost-effective and readily reproducible, rendering them highly helpful for the purpose of disease surveillance. The impact of vitamin D on inflammatory mediators and its role in the progression from prediabetes to type 2 diabetes has been seen. This study aims to investigate hematological markers, glycemic management, and vitamin D status among individuals with prediabetes.<strong>Methods:</strong> A retrospective investigation was performed on a cohort of 270 persons with prediabetes (5.7-6.4% glycated hemoglobin levels) and 299 participants with normal blood glucose levels. In order to conduct a comparison of hematological indicators between two groups, statistical analyses including chi square analysis and the t test were employed. The analysis of variance (ANOVA) statistical method was employed to analyze the components within three distinct categories of Vitamin D levels: acceptable (more than 75 nmol/L), inadequate (ranging from 50 to 74.9 nmol/L), and deficient (50 nmol/L). The odds ratio for prediabetes was obtained through the utilization of regression analysis.<strong>Results:</strong> The study observed a statistically significant decrease in vitamin D levels among individuals with prediabetes (mean 57.91 ± 20.83, p = 0.05). The group of individuals with prediabetes exhibited significantly higher values for the neutrophil lymphocyte ratio (2.10 ± 0.85; p = 0.05), platelet lymphocyte ratio (137.70 ± 43.70; p = 0.05), mean platelet volume (8.55 ± 3.00; p = 0.001), and red cell distribution width (12.65 ± 1.31; p = 0.05). The present study observed a statistically significant positive correlation between declining levels of vitamin D and increasing trends in the neutrophil lymphocyte ratio, platelet lymphocyte ratio, and red cell distribution width in individuals with prediabetes. The study revealed that the mean platelet volume had a noteworthy association with the development of prediabetes.<strong>Conclusions:</strong> The neutrophil lymphocyte ratio, platelet lymphocyte ratio, red cell distribution width, and mean platelet volume are emerging inflammatory markers that can be employed for monitoring purposes in patients with prediabetes. However, it is important to note that these indicators should be utilized in combination with an assessment of Vitamin D status.
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Bazaron, B. Z., T. N. Khamiruev, S. M. Dashinimaev, G. M. Shkuratova, and M. L. Bondarchuk. "Assessment of some hematological indicators of breeding falls of the zabaikalsky breed." Veterinariya, Zootekhniya i Biotekhnologiya 1, no. 2 (2021): 36–42. http://dx.doi.org/10.36871/vet.zoo.bio.202102005.
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The results of studying the morphological and biochemical parameters of the blood of young horses of the Trans-Baikal breed, depending on the zone of their breeding and age, are presented. The study of hematological parameters is one of the most important diagnostic methods for assessing the physiological and clinical state of animals. The research material was stallions at the age of 12, 18, 24 and 36 months. It was found that hematological parameters were within physiological norms, while in stallions of the forest-steppe zone they were higher in comparison with analogs of the steppe zone. With age, there is a decrease in the estimated hematological parameters in the experimental stallions.
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Allu, Muslim Abbas, Hassan Mohsen Hassan, and Aqeel Abbas Allu. "Comparison of Hematological Parameters in Sheep’s infected with Echinococcosis with Mice Balb\C Strain Injected by Protoscoleses." Cognizance Journal of Multidisciplinary Studies 5, no. 3 (2025): 124–29. https://doi.org/10.47760/cognizance.2025.v05i03.010.
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A total of 125 sheep during six month slaughtered in Dohuk animal farms and examined the hematological parameters for them, were investigated in 42 sheep infested by CE. Values of hemoglobin and red blood cells and packed cell volume in sheep infested by E. granulosus, appear low compared with reference values. While hyper eosinophilia, lymphocyte and monocyte was high, and this typical of parasitic diseases. In mice Balb\c strain and sheep found that the number of white blood cell has increase (eosinophilia, lymphocyte and monocyte) and decrease of neutrophils after counting the differential WBC of positive group and increase of MCV, MCH, MCHC. The aim of this study was to investigate the value of hematological parameters for infected group and comparison with control group of sheep and mice. And assess the hematological indicators in sheep infested naturally by CE and comparison these indicators with the hematological indicators in mice Balb\c strain injected by hydatid cyst protoscoleses.
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Muslim, Abbas Allu, Mohsen Hassan Hassan, and Abbas Allu Aqeel. "Comparison of Hematological Parameters in Sheep's infected with Echinococcosis with Mice Balb\C Strain Injected by Protoscoleses." Cognizance Journal of Multidisciplinary Studies (CJMS) 5, no. 3 (2025): 124–29. https://doi.org/10.47760/cognizance.2025.v05i03.010.
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A total of 125 sheep during six month slaughtered in Dohuk animal farms and examined the hematological parameters for them, were investigated in 42 sheep infested by CE. Values of hemoglobin and red blood cells and packed cell volume in sheep infested by E. granulosus, appear low compared with reference values. While hyper eosinophilia, lymphocyte and monocyte was high, and this typical of parasitic diseases. In mice Balb\c strain and sheep found that the number of white blood cell has increase (eosinophilia, lymphocyte and monocyte) and decrease of neutrophils after counting the differential WBC of positive group and increase of MCV, MCH, MCHC. The aim of this study was to investigate the value of hematological parameters for infected group and comparison with control group of sheep and mice. And assess the hematological indicators in sheep infested naturally by CE and comparison these indicators with the hematological indicators in mice Balb\c strain injected by hydatid cyst protoscoleses.
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M Khazaal, Neam, Hasan F Alghetaa, and Mohammed Baqur S Al-Shuhaib. "Hematological Parameters as Indicators for Litter size and Pregnancy Stage in Awassi Ewes." Iraqi Journal of Veterinary Medicine 47, no. 1 (2023): 68–73. http://dx.doi.org/10.30539/ijvm.v47i1.1504.
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 Physiological status and litter size can indeed have a significant impact on ewes' hematological parameters, which are essential indicators of their health. Therefore, this study examined the hematological profiles of ewes during pregnancy with single and twins in the Awassi ewes. The present study involved 232 ewes in good health and at sexual maturity. Among them, 123 ewes had single pregnancies, while 109 ewes had twin pregnancies. The age range of the ewes included in the study was between 3.5 and 4.5 years. Hematological tests were conducted on the sheep's blood samples promptly following collection. The findings demonstrated variations in hematological parameters among pregnant ewes, with differences based on litter size. Ewes carrying twin pregnancies exhibited significantly higher levels of red blood corpuscular, hemoglobin, packed cell volume, and mean corpuscular hemoglobin concentration during pregnancy. In comparison to single-pregnant ewes, Awassi ewes with twin pregnancies displayed elevated counts of white blood cells, lymphocytes, granulocytes, and granulocyte percentage compared to ewes with single pregnancies. Awassi ewes with twin pregnancies also exhibited a strong positive correlation with the leukocytes and erythrocytes constituents. In conclusion, these findings indicate that litter size significantly influences hematological parameters, highlighting the importance of considering the physiological status and litter size as indicators of ewes' health. The findings have practical implications in sheep breeding and reproduction, as they can be utilized to enhance the diagnosis, prognosis, and treatment of related conditions.
 
 
 
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Jožef, Ivana, Marcela Šperanda, Mislav Đidara, Drago Bešlo, and Vesna Gantner. "The Variability of Biochemical and Hematological Parameters Depending on the Mastitis Occurence in Dairy Cows." Poljoprivreda 28, no. 1 (2022): 68–76. http://dx.doi.org/10.18047/poljo.28.1.10.
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With the aim of determination of biochemical indicators variability in the plasma and milk and hematological indicators regarding the daily lactose content classes (indicating the mastitis risk) and somatic cell counts classes (indicating the animal’s health status), blood and milk of 75 Holstein cows were sampled. The cows were reared on a commercial dairy farm. A statistical analysis demonstrated that the lactation stage, parity, and statistically significant monthly measurement P < 0.01) affected both the biochemical and hematological parameters. The differences between the analyzed biochemical and hematological parameters due to the mastitis score classes (according to the daily lactose content, DLC, and the somatic cell count, SCC) were present and statistically significant (P < 0.05) in some traits. Furthermore, different trends regarding the mastitis scoring (DCL of SCC) were determined in some traits. Therefore, when using the test-day records as an animal’s mastitis risk and health status indicator, both scoring ways should be used. Finally, in the case of a mastitis risk or mastitis occurrence, other diagnostic methods (such as various mastitis tests) should be used for the sake of an unambiguous detection.
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Baiguzhekov, M. "THE STUDY OF HEMATOLOGICAL AND FUNCTIONAL INDICATORS IN STUDENTS DURING THE EXAMINATION SESSION." Journal of Educational Sciences 54, no. 1 (2018): 51–58. http://dx.doi.org/10.26577/jes-2018-1-489.
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Reshetnyak, V. V., A. A. Stekolnikov, V. V. Burdeyniy, L. V. Malakhova, and M. D. Yelokhin. "INFLUENCE OF THYMOGEN IN DISEASES OF HOOVES IN MOOSES ON HEMATOLOGICAL INDICATORS." International Journal of Veterinary Medicine, no. 3 (October 17, 2022): 176–81. http://dx.doi.org/10.52419/issn2072-2419.2022.3.176.
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The article presents data reflecting hematological parameters in domesticated moose with standard treatment, as well as in combination with thymogen in case of damage to the hooves.Experiments were performed on three groups of moose cows 2 months before calving: control (n=10, healthy) and two experimental groups (n=3 in each): d - with a more severe one and with the additional inclusion in the treatment regimen of a five-day course of thymogen, at a dose of 300 μg / animal, intramuscularly.Blood was taken before, on the 14th and 30th days of the experiment. Visually, the number of erythrocytes, leukocytes, leukogram, ESR were taken into account.It has been established that hoof injuries in sick moose cows are accompanied by changes in the hematological profile. They register a higher level of erythrocytes, leukocytes, lymphocytes, absolute and relative - stab and segmented neutrophils, against the background of lower levels of basophils, eosinophils, monocytes.It was shown that the direction of the dynamics of hematological parameters in the animals of the control and the 1st experimental groups had differences in 12 out of 14 indicators, and compared with the 2nd experimental group, only in six. The highest degree of coincidence between the control and the 1st experimental group was noted on the 14th day in seven cases (50%), on the 30th - in four (28.6%), compared with 2 th, moose cow additionally treated with thymogen in 11 (78%) and seven (50%) cases, in the complex on the 14th-30th in two (14.3%) and seven (50%) cases, respectively.This assessment of the coincidence of the direction of the dynamics of hematological parameters of the experimental groups in comparison with the control group indicates that complex therapy supplemented with thymogen allows to normalize the dynamics of hematological parameters.
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Sova, E. A., and I. P. Drozd. "Dose formation and hematologic effects with prolonged internal exposure of rats by isotope 131I." Nuclear Physics and Atomic Energy 15, no. 4 (2014): 359–69. https://doi.org/10.15407/jnpae2014.04.359.
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Processes in single dose formation and long-term domestic revenue of 131I in rats was investigated. Original method of estimating absorbed doses in hemacyte for makrodozimetric indicators was proposed. Dose factors for hemacyte and the dynamics of the blood-forming organs doses for two cases of prolonged exposure was calculated. Hematologic effects were studied for two variants of entry of the isotope. Peculiarities of doses formation and identified hematological effects are discussed.
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Кucher, A. V., S. V. Khodus, and O. B. Prikhodko. "Analysis of indicators of endogenous intoxication in patients with communityacquired pneumonia associated with COVID-19." Bulletin Physiology and Pathology of Respiration 1, no. 84 (2022): 63–69. http://dx.doi.org/10.36604/1998-5029-2022-84-63-69.
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Aim. To assess the prognostic significance of hematological parameters of endogenous intoxication syndrome at the stage of routing patients with pneumonia associated with COVID-19.Materials and methods. 146 case histories of patients were analyzed, divided into 2 groups: patients who were referred for treatment to intensive care units based on the results of routing in the admission and diagnostic department (ADD) and patients referred for treatment to pulmonology departments. Upon admission of patients to the hospital, according to the case histories at the stage of ADD, an assessment of the clinical blood test was made, the calculation of hematological indicators of intoxication. Based on the data obtained, a ROC analysis was performed to determine the prognostic significance of hematological indicators of intoxication.Results. In patients who were in intensive care units, at the stage of sorting in the ADD, the concentration of leukocytes and the percentage of neutrophils were higher by 25.9 and 16.2%, respectively, in comparison with patients referred for treatment to the pulmonology departments, however, the percentage of lymphocytes and the quantitative concentration of erythrocytes was lower by 26.6 and 8.3%, respectively. The integral indicator of intoxication in patients in intensive care was higher by 38.6%, the leukocyte index of intoxication by 74.3% and the index of the ratio of neutrophils to lymphocytes by 81.5%. In patients of the same group, the index of the ratio of neutrophils to monocytes was lower by 28.7%, the index of the ratio of lymphocytes to monocytes by 44.9%. The sensitivity of the integral indicator of intoxication was 73.3%, the specificity was 51.2%; in the leukocyte index of intoxication – 57.3 and 51.2%, respectively; the sensitivity of the index of the ratio of neutrophils to monocytes was 57.3%, the specificity was 59.1%; the same figures for the index of the ratio of neutrophils to lymphocytes were 68 and 60%, respectively.Conclusion. It can be concluded that there is a rather high clinical prognostic value in the routing of patients with community-acquired pneumonia caused by COVID- 19 at the stage of initial examination in the ADD, such hematological parameters of intoxication as the integral index of intoxication and the index of the ratio of neutrophils to lymphocytes. We believe that hematological indicators of intoxication can complement prognostic scales and be used as another criterion in determining the routing of patients in ADD.
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Borodulina, E. A., Zh P. Vasneva, B. E. Borodulin, E. S. Vdoushkina, L. V. Povalyaeva, and K. A. Mateesku. "Hematological indicators for lung damage caused by COVID-19 infection." Russian Clinical Laboratory Diagnostics 65, no. 11 (2020): 676–82. http://dx.doi.org/10.18821/0869-2084-2020-65-11-676-682.
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During the pandemic of a new coronavirus infection one of the most serious complications is pneumonia. When entering a specialized pulmonology Department, the presence of pneumonia is confirmed by computed tomography (CT), the etiology is confirmed by the detection of SARS-CoV-2 RNA by PCR, the article analyzes the indicators of blood analysis when patients are admitted to the hospital. All admitted patients were divided into 2 groups. Group 1 of the study - with a new coronavirus infection Covid-19, confirmed by the detection of PCR-RNA SARS-CoV-2 (n=27). Group 2 consisted of 65 patients (70.7%) with lung tissue damage characteristic of Covid-19 according to CT, who had a negative analysis of PCR-RNA SARS-CoV-2. Statistically significant deviations were shown in a decrease in the percentage and absolute content of lymphocytes, monocytes and platelets, and an increase in neutrophils. The comparative analysis in the groups with positive and negative PCR analysis for the detection of SARS-CoV-2 RNA showed no statistically significant differences. It can be assumed that with the similarity of clinical manifestations and CT-data, a negative result of PCR-RNA SARS-CoV-2 can be diagnosed as «lung damage caused by COVID-19 infection».
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Lagutkina, Lina Yurievna, Elena Evgrafova, Evgeniia Germanovna Kuzmina, and Alexey Mikhaylovich Mazlov. "HEMATOLOGICAL AND BIOCHEMICAL INDICATORS OF AUSTRALIAN RED-CLAW CRAYFISH HEMOLYMPH." Vestnik of Astrakhan State Technical University. Series: Fishing industry 2021, no. 2 (2021): 134–43. http://dx.doi.org/10.24143/2073-5529-2021-2-134-143.
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The article describes Australian red claw crayfish, Cherax quadricarinatus, which is currently one of the most promising cultivation targets. However, to increase production volumes, it is necessary to improve cultivation technologies, which should be based on the data of physiological and biochemical parameters. An objective method for monitoring the physiological state 
 of Australian red claw crayfish in the artificial conditions is determining its hematological and biochemical indicators that complement the general characteristics of hemolymph and later define its physiological norm. When giving the objects the compound feed, which the authors produced by their own recipe, there was recorded a high level of total hemolymph protein of 40.8 ± 4.5 g/l. According to the results of biochemical research, the cholesterol content in the hemolymph of Australian crayfish was 3.2 ± 0.6 mmol/l, and the concentration of lipoproteins was 0.8 ± 0.2 g/l (levels within the reference values). When considering the hemogram of hemolymph there were found the dominant types and linear dimensions of native formed elements. The diameter of agranulocytes in Australian freshwater crayfish varied from 85 to 90 μm, semi-granulocytes - from 90 to 95 μm, granulocytes - from 65 to 78 μm, transparent cells differed by greater variability in size, which ranged from 85 to 120 μm. The part of granulocytes in relation to other shaped elements exceeded 50%, for transparent cells it turned out to be above 20%, for semi-granulocytes - about 15% and for agranulocytes - about 5%, which means that the latter form the rarest group. The established ratios are specific for Cherax quadricarinatus, its hemocytic characteristics greatly differs from Astacus leptodactylus, which is the main object of comparative research. The results of comparative analysis of the cellular composition of the hemolymph of the Australian freshwater crayfish Cherax quadricarinatus (Von Martens, 1868) demonstrate the taxonomic specificity of this representative of freshwater aquaculture
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López-Verdugo, Fidel, Janette Furuzawa-Carballeda, Fernanda Romero-Hernández, et al. "Hematological indices as indicators of silent inflammation in achalasia patients." Medicine 99, no. 9 (2020): e19326. http://dx.doi.org/10.1097/md.0000000000019326.
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Savchuk, I. M., and S. P. Kovalyova. "Hematological indicators of young bulls fed with genetically modified soybeans." Taurian Scientific Herald, no. 137 (2024): 459–66. http://dx.doi.org/10.32782/2226-0099.2024.137.54.
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Sashnina, L. Yu, A. G. Shakhov, Yu Yu Vladimirova, K. V. Tarakanova, and V. I. Morgunova. "CHANGES IN HEMATOLOGICAL AND BIOCHEMICAL INDICATORS IN SOWS DURING GESTATION." Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine 58, no. 3 (2022): 142–45. http://dx.doi.org/10.52368/2078-0109-2022-58-3-142-145.
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The article presents the results of studying changes in hematological and biochemical indicators in pregnant sows during different gestation periods on an industrial pig breeding farm. It has been established that more pronounced changes are noted with an increase in the duration of gestation and are manifested by a decrease in the serum content of erythrocytes, hemoglobin, color index (globular value), platelets, albumins, iron, an increase in hematocrit, ESR, globulins to maintain balance in the hemostasis system.
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Tatarintseva, Z., Е. Kosmacheva, А. Shyk, and А. Batchaeva. "Hematological indicators as predictors of atrial fibrillation after cardiac surgery." Vrach 35, no. 1 (2024): 15–18. http://dx.doi.org/10.29296/25877305-2024-01-03.
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Newly diagnosed postoperative atrial fibrillation (NDPAF) is one of the most common complications after cardiovascular surgery, provoking early and late complications, such as cardiovascular, thromboembolic complications, cerebral circulation disorders, prolonged hospital stay and repeated hospitalizations to the intensive care unit and hospital. Objective. To identify biochemical and clinical predictors of NDPAF in patients who underwent open-heart surgery for any indication. Materials and methods. The study included patients operated in the cardiac surgery department No.2 of the Research Institute – Prof. S.V. Ochapovsky Territorial Clinical Hospital One (Krasnodar) in the period from January 1, 2020 to January 1, 2021. During the analyzed period of time, open heart surgery was performed in 1503 patients, of whom 158 (10.5%) had NDPAF. Results. Hematological/biochemical parameters include low levels of hemoglobin (<12.5 g/dl), hematocrit (<35%), erythrocytes (<4,2•1012/L), and high levels of lymphocytes (>3,0•109/L), bilirubin (20.5 mmol/L), creatinine (115 mmol/L), urea (8.3 mmol/L), aspartate aminotransferase (>35 U/L), alanine aminotransferase (>55 U/L), C-reactive protein (>5 mg/L) were associated with an increased frequency of NDPAF in single-factor analysis (p<0.05 for all comparisons). Conclusion. Hematological indicators can predict the risk of atrial fibrillation before surgery. The study of risk factors for NDPAF will allow to effectively influence them, thereby preventing the possibility of arrhythmia and improving the prognosis for postoperative complications and survival.
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Kryvoruchenko, D. "Hematological parameters of dogs for parasitism Dirofilaria immitis." Ukrainian Journal of Veterinary and Agricultural Sciences 5, no. 1 (2022): 36–41. http://dx.doi.org/10.32718/ujvas5-1.06.
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The relationship between helminths and the host is built on a subtle molecular biological basis. Their pathogenic effect is characterized by the mechanical, toxic, inoculating effect on the host organism and the state of reactivity of his organism, immunological and allergic reorganization. It has been proved that helminths of the species Dirofilaria immitis are the most pathogenic nematodes of this genus because the localization of the imaginal stage of the parasite causes more complex pathogenesis of the invasion. The study aimed to establish changes in hematological parameters of dogs infected with D. immitis, considering the intensity of microfilariasis invasion. Studies have shown that the intensity of the invasion of up to 20 larvae/cm3 in the blood of dogs, significant changes in the number of erythrocytes, leukocytes, platelets, hemoglobin, and hematocrit and ESR were not found. The intensity of the invasion of 20–40 larvae/cm3 in infected dogs in the blood decreases the number of erythrocytes by 11.92 % (P < 0.05), the hemoglobin content by 16.33 % (P < 0.05), the hematocrit by 12.70% (P < 0.05) and the number of leukocytes increases by 15.17 % (P < 0.05). Indicators of the intensity of invasion of 40–60 larvae/cm3 in infected dogs showed more significant changes in the blood, which are characterized by a decrease in the number of erythrocytes by 25.54 % (P < 0.001), platelets by 34.03 % (P < 0.01), hemoglobin content by 30.86 % (P < 0.001), hematocrit by 20.56 % (P < 0.001) and an increase in the number of leukocytes by 32.75 % (P < 0.001) and ESR by 1.84 times 0.001). At indicators of the intensity of invasion of more than 60 larvae/cm3, in dogs significant (P < 0.001) decrease in the number of erythrocytes by 47.21 %, thrombocytes by 42.84 %, the content of hemoglobin by 42.27 %, the indicator of hematocrit by 41.57 % and an increase in the number of leukocytes by 44.98 % and ESR by 2.51 times. In the leukoform of dogs with increasing rates of microfilariae invasion, the number of eosinophils gradually increases to 62.38 % (P < 0.001), rod-shaped neutrophils to 27.48 % (P < 0.05), monocytes to 23.21 % (P < 0.01) and the number of lymphocytes is reduced to 45.45 % (P < 0.001). The data obtained indicate the importance of determining these indicators for heartworm disease, which complements the picture of clinical examination of animals and will allow more effective treatment of dogs in this invasion.
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Al-Salahy, Mohamed, Bushra Shnawa, Gamal Abed, Ahmed Mandour, and Ali Al-Ezzi. "Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen." Interdisciplinary Perspectives on Infectious Diseases 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/5954394.
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Plasmodium falciparummalaria is the most common infection in Yemen. The present study aims to investigate changes in hematological and hepatic function indices ofP. falciparuminfected individuals. This study included 67 suspectedfalciparummalarial patients attended in clinics and rural Abs Hospital (Tehama, Hajjah), Yemen, from October 2013 to April 2014. The diagnosis of malaria was confirmed by thick and thin film with Giemsa staining of malaria parasite. Hematological parameters and serum levels of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and bilirubin (total and direct) as test indicators of liver function were studied. Patients with parasitaemia tended to have significantly lower hemoglobin, hematocrit, white blood cell count, lymphocytes, and platelets, compared with healthy normal subjects. Neutrophils levels were significantly higher in cases offalciparummalaria in comparison to healthy normal subjects. Serums AST, ALT, ALP, and bilirubin (total and direct) infalciparummalaria patients were significantly higher (p<0.0001) than those offalciparummalaria of free individuals. Hematological and liver dysfunctions measured parameters were seen associated with moderate and severe parasitaemia infection. This study concludes that hematological and hepatic dysfunction parameters could be indicator of malaria in endemic regions.
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Konstantinova, L. I., E. D. Okhlopkova, L. D. Olesova, A. I. Yakovleva, L. V. Mironova, and A. N. Romanova. "Hematological blood parameters in residents of Yakutsk city recovered from coronavirus infection COVID-19." YAKUT MEDICAL JOURNAL 84, no. 4 (2023): 16–20. https://doi.org/10.25789/ymj.2023.84.04.
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The study is devoted to a comparative analysis of the results of the effect of COVID-19 coronavirus infection on hematological blood parameters in patients who have been ill after three, six, nine and twelve months. Monitoring of hematological parameters is important for the identification and control of patients who have undergone COVID-19, who need additional assistance, and stratification of the risk of severe course of the disease. The study involved 161 residents of Yakutsk aged 20 to 72 years who had suffered COVID-19 in different periods of the pandemic. The study of hematological parameters showed that the average indicators of the morphological composition of red and white blood in people who have had COVID-19 correspond to generally accepted standards, with the exception of the tendency to increase monocytes, basophils, ESR and a slight decrease in MCHC indicators, which indicates a recently transmitted infectious disease. Keywords: coronavirus infection, COVID-19, SARS-CoV-2, blood test, hematological parameters of blood.
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Egorova, V. I., and I. V. Volkova. "Dynamics of integral hematological indices of fish in chronic intoxication." Fisheries, no. 1 (February 26, 2025): 81–88. https://doi.org/10.36038/0131-6184-2024-1-81-88.
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Today, laboratory practice has a rich arsenal of methods for dynamic control over the course of pathological processes in the body of fish. Quantitative indicators of blood leukocytes and, especially, indicators of its leukocyte formula are important re-search methods in the diagnosis of a wide variety of pathological conditions. To objectively assess these results, a number of indicators have now been proposed that determine the course of pathological processes in the body, but these indicators are not used in real fisheries science and aquaculture.The purpose of our study was to study the dynamics of integral hematological indices of fish against the background of chronic experimental intoxication.As a result of the research, it was found that the use of hematological indices in fish can provide additional information about the course of the toxic process, including the course of pathological processes of other etiology. It was revealed that the deter-mination of integral leukocyte indices can be an addition or alternative to complex immunological and biochemical studies.
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Sokhibova, Z. R., and М. R. Turdiyev. "Some Features Of Laboratory Indicators Of Micro And Macro-Elementary Condition Of The Organism Of Female Age Women Innormality And In Iron Deficiency." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 02 (2021): 140–45. http://dx.doi.org/10.37547/tajmspr/volume03issue02-21.
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Using unified and developed methods, some hematological, biochemical, and micro-and macronutrient status indicators were studied in women of fertile age with a normal health index and iron deficiency. It is shown that there are certain pathological fluctuations in some hematological, biochemical and essential hematopoietic microelements in women of fertile age with the development of iron deficiency. In particular, there is a hypoproteinemia, hypoferremia, hypozincemia, hypocupremia and hypertransaminasemia.
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Ahmad, Zaheer, Ming Xie, Yongbao Wu, and Shuisheng Hou. "Effect of Supplemental Cyanocobalamin on the Growth Performance and Hematological Indicators of the White Pekin Ducks from Hatch to Day 21." Animals 9, no. 9 (2019): 633. http://dx.doi.org/10.3390/ani9090633.
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The experiment was conducted to evaluate the requirement of cyanocobalamin of male Pekin ducks from hatch to 21 days of age. A total of three-hundred-eighty-four, one-day-old meat-type male Pekin ducks were randomly allocated to six treatments, i.e., dietary cyanocobalamin (vitamin B12) concentrations of 0.00, 0.02, 0.04, 0.06, 0.08 and 1.00 mg/kg, respectively in their feed. Each treatment had eight replicated pens with eight ducks for each pen. Feed and water were provided ad libitum. The experiment was conducted for 21 days. Different growth parameters including average daily weight gain (ADG), average daily feed intake (ADFI), feed conversion ratio (FCR), and hematological indicators were evaluated because, on the basis of hematological indicators, the health and nutritional status of an animal can be accessed. It is observed that supplemental cyanocobalamin has no significant effect on ADG, ADFI, and FCR but it improves hematological parameters such as white blood cells, red blood cells, and its indices and platelet counts compared to the control group (p < 0.05). On the basis of growth performance and hematological indicators it is concluded that 0.02 mg cyanocobalamin/kg of feed is the dietary requirement of male Pekin ducks from hatch to day 21 of age.
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Bolotov, А. A., V. G. Barchukov, A. S. Galuzin, A. M. Ten, and O. V. Onopchenco. "Using Hematological Indicators to Predict the Results of Competitions of Swimmers Based on Probabilistic Estimation." A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin, no. 4 (December 2023): 10–18. http://dx.doi.org/10.33266/2782-6430-2023-4-10-18.
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Purpose: The article discusses probabilistic approaches to the analysis of hematological indicators of athletes in swimming, their use for assessing the functional state in order to predict the success of performances in competitions and the creation of a computer system for assessing the prediction of successful performances based on the most significant hematological signs. Methodology of the work: On the basis of probabilistic approaches, a method for assessing the influence of hematological parameters on the determination of the functional state (in order to predict the success of performances) of athletes in competitions is proposed. Two assessments of the significance of indicators are considered: an integral assessment and an assessment of the influence of the values of each feature on the forecast result. The integral significance assessment is designed to select the features that most strongly affect the prediction result, and the assessment of the influence of the values of each feature allows you to determine the impact of the values of each indicator on the success prediction and serves to explain the prediction result. Results: The use of estimates of the integral significance of signs made it possible to reduce the number of hematological blood parameters from 18 to 8 in order to develop a computer system for evaluating the prediction of the success of athletes in competitions. A technique for converting continuous indicators into a discrete scale with three gradations based on the criterion of the maximum integral significance of the indicator is proposed. An assessment of the influence of each feature gradation on the probability of a successful forecast is given. A computer system for predicting the success of the performance of athletes has been developed. A technique for assessing the quality of the conclusions of the system for predicting the success of the performance of athletes based on the Monte-Carlo methods is proposed. Scope of application of the results: The results of the work are of applied importance for the construction of computer systems for assessing the functional state and predicting the success of athletes’ performances in order to improve the quality of the selection of candidates both in team disciplines and in individual competitions of athletes. Conclusions: The use of assessments of the integral significance of signs made it possible to reduce the number of hematological indicators for the development of a system for assessing the prediction of the success of athletes’ performance in competitions. The results of statistical testing of the methodology for assessing the quality of the conclusions of the system for predicting the success of the performance of athletes on Monte-Carlo approaches showed a fairly high accuracy (about 93%) of the prediction system on the available volume of actual data, which allows us to conclude that it is working and the possibility of further development.
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Zaid Hazem, Donia, Esraa Adel Mahmood, and Anfal Saleh Mohammed. "Hematological Indicators of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Malaria-Infected Individuals." JANUARY 2024 20, no. 1 (2024): 46–51. http://dx.doi.org/10.47836/mjmhs.20.1.7.
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Introduction: Malaria, a life-threatening infectious disease caused by Plasmodium parasites, continues to be a major global health concern, particularly in regions with high transmission rates. This retrospective cohort study aimed to investigate the hematological indicators of G6PD deficiency in individuals infected with malaria. The study utilized medical records and laboratory test results to analyze the hematological parameters and markers in individuals with confirmed malaria and G6PD deficiency. Methods: Data were collected from the laboratory unit of Mosul Teaching Hospitals in Ninevah Province, Iraq, from March 2021 to November 2022. The study population consisted of individuals diagnosed with malaria and with available G6PD deficiency test results. G6PD deficiency was determined by measuring the G6PD enzyme activity in the patient’s blood. Hematological parameters, including complete blood counts, platelet counts, and red blood cell indices, were recorded using a laboratory information system. Results: The study population exhibited a relatively low prevalence of G6PD deficiency, with no significant differences observed in age or gender distribution between individuals with and without G6PD deficiency. The distribution of malaria types did not differ significantly between the two groups. However, patients with G6PD deficiency showed a significantly higher monocyte count, indicating a potential association between G6PD deficiency and altered monocyte response during malaria infection. The clinical significance of this finding requires further investigation. Conclusion: This study sheds light on the hematological indicators of G6PD deficiency in individuals infected with malaria. The findings suggest a potential relationship between G6PD deficiency and altered monocyte response during malaria infection.
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Ruzikulov, Rakhmatullo, Ikrom Fayzullayev, Ra’no Mirsaidova, Durdona Sulaymanova, and Mexrangiz Ergasheva. "The effect of the probiotic ‘Maxilac’ on the growth dynamics, hematological and biochemical indicators of Karakul lambs." BIO Web of Conferences 181 (2025): 01034. https://doi.org/10.1051/bioconf/202518101034.
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This article expounds on the research undertaken and the results obtained in order to study the effect of probiotic ‘Maxilac’ on the growth dynamics, hematological and biochemical parameters of newborn Karakul lambs. The conducted studies revealed differences in live weight gain, hematological and biochemical parameters of Karakul lambs of control group 1 and experimental group 2, to which the probiotic ‘Maxilac’ was applied. The rumen microflora of experimental Karakul lambs, which were administered probiotic ‘Maxilac’, was also studied. Conclusions were drawn regarding the effective effect of probiotic ‘Maxilac’ on live weight gain, hematological and biochemical parameters of Karakul lambs. The results of this study demonstrate the significant role of probiotics in veterinary practice and karakul breeding.
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Xu, Pan, Leilei Cui, Tao Huang, et al. "Genome-wide identification of quantitative trait transcripts for blood traits in the liver samples of a White Duroc × Erhualian F2pig resource population." Physiological Genomics 48, no. 8 (2016): 573–79. http://dx.doi.org/10.1152/physiolgenomics.00123.2015.
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Blood cell counts are important clinical indicators for health status. The liver plays a crucial role in food digestion and metabolism and is also a blood-forming organ. Here, we conducted a whole-genome quantitative trait transcript (QTT) analysis on 497 liver samples for 16 hematological traits in a White Duroc × Erhualian F2pig resource population. A total of 20,108 transcripts were explored to detect their association with hematological traits. By using Spearman correlation coefficients, we identified 1,267 QTTs for these 16 hematological traits at the significance threshold of P < 0.001. We found 31 candidate genes for erythrocyte and leukocyte-related traits by a look-up of human and pig genome-wide association study results. Furthermore, we constructed coexpression networks for leukocyte-related QTTs using weighted gene coexpression analysis. These QTTs were clustered into two to eight modules. The highest connection strength in intramodules was identified in a module for white blood cell count. In the module, USP18, RSAD2, and OAS1 appeared to be important genes involved in interferon-stimulated innate immune system. The findings improve our understanding of intrinsic relationships between the liver and blood cells and provide novel insights into the potential therapeutic targets of hematologic diseases.
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Mosaed, Othman Mohsen, Radfan Saleh Abdullah, and Maysa Saeed Al Noban. "HEMATOLOGICAL CHANGES ASSOCIATED WITH COVID-19 INFECTION IN ADEN/ YEMEN." Electronic Journal of University of Aden for Basic and Applied Sciences 5, no. 2 (2024): 180–85. http://dx.doi.org/10.47372/ejua-ba.2024.2.351.
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Chronic Hematological alterations in COVID-19 patients range from mild to severe, with common changes including lymphopenia, neutrophilia, and thrombocytopenia. The gold standard for diagnosis is the polymerase chain reaction (PCR) test, which is highly specific and sensitive for detecting SARS-CoV-2 genetic material. The study was a single isolation center retrospective analysis of 200 patients with COVID-19 confirmed cases. The hematological indicators were taken after sample blood collected from the staff of Central Public Health Laboratory to determine the changes, and compared between different grades of severity and prognosis with the hematological indicators. The data was analyzed using Statistical Package for the Social Sciences (SPSS) version 22.0. simple frequencies and percentage were used, while chi-square test used to determine the association between variables. Males consisted 73.5% in this study, while 63% of participants suffered from moderate severity. Related to the hematological changes; and comparisons made according to real-time PCR test results revealed that the Lymphocytopenia and leukocytosis presented among 47.5% and 46.5% respectively with significance association with illness severity and outcome of patients with p-value< 0.05. hematological changes in COVID-19 patients are a common and significant aspect of the disease. Lymphopenia, neutrophilia, thrombocytopenia, and increased levels of inflammatory markers are frequently observed. These hematological abnormalities are associated with disease severity, poor clinical outcomes. Blood parameters aid in COVID-19 diagnosis and prognosis, with abnormal hematological parameters providing early evidence. However, interpretation should consider limitations, sample size, and potential biases. Further research needed.
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Vatnikov, Y. A., D. A. Blumenkrants, and E. M. Lenchenko. "DYNAMICS OF HEMATOLOGICAL AND BIOCHEMICAL INDICATORS IN RESPIRATORY SYNDROME OF LAMBS." THEORETICAL & APPLIED PROBLEMS OF AGRO-INDUSTRY 52, no. 2 (2022): 40–45. http://dx.doi.org/10.32935/2221-7312-2022-52-2-40-45.
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Respiratory Diseases 2010–2020 were the cause of death of 4,8–12,6 % of lambs. A trend towards an increase in the proportion of factorial infectious diseases was established, the epizootic index – 1,0, the breadth of distribution – 10,53. The mass fraction of respiratory diseases in lambs – 11,7–19,94 %. To reveal the pathogenetic mechanisms of the infectious process, prevent animal diseases and obtain safe livestock products, it is a priority to study the dynamics of hematological and biochemical parameters using standardized multilevel diagnostic algorithms. The development of the pathological process was characterized by a complex respiratory syndrome and was accompanied by cough, shortness of breath, nasal discharge, rhinitis, pharyngitis, tonsillitis, laryngitis, epiglottitis, laryngeal edema, tracheitis, bronchitis, hyperemia and pulmonary edema, bronchopneumonia, pulmonary emphysema, pleurisy, hydrothorax, pneumothorax . The dynamics of hematological parameters was characterized by an increase in the total number of leukocytes, neutrophils, eosinophils, basophils, lymphocytes and monocytes. Biochemical parameters were characterized by a decrease in total protein and glucose. An increase in urea and alkaline phosphatase was observed. A violation of the water and electrolyte balance was established: a decrease in the content of potassium, sodium and magnesium. An increase in the concentration of C-reactive protein was established – 9,34±2,80–11,54±1,08; decrease in the concentration of immunoglobulin IgA – 0,43±0,02–0,50±0.04 mg/ml; IgG – 7,60±0,19–12,40±2,10 mg/ml. The development of pathological processes is due to a decrease in immune reactions that prevent the adhesion of pathogens to the surface of epithelial cells. Mean adhesion score, SPA≥4,0 isolates: E. coli: O33:F41, O2:A20; K. pneumoniae; P. vulgaris; P. aeruginosa; S. aureus; C. albicans. Microscopic examination of swab preparations from the nasal cavity of sick lambs revealed predominantly coccal forms of microorganisms, as well as a large amount of mucus, erythrocytes, leukocytes, ciliated epithelial cells.
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Houston, Arthur H. "Review: Are the Classical Hematological Variables Acceptable Indicators of Fish Health?" Transactions of the American Fisheries Society 126, no. 6 (1997): 879–94. http://dx.doi.org/10.1577/1548-8659(1997)126<0879:ratchv>2.3.co;2.
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Ostadrahimi, Alireza, Vahideh Sadra, Amir Bahrami, et al. "What hematological and endocrinal indicators are important in COVID-19 infection?" Health Promotion Perspectives 12, no. 2 (2022): 212–17. http://dx.doi.org/10.34172/hpp.2022.26.
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Background: Clinical evidence of endocrine involvement in coronavirus disease needs further investigation. The aim of the present study was to assess the relationship between hematology and endocrine parameters in coronavirus disease 2019 (COVID-19) infection. Methods: In the present cross-sectional study, a total of 320 patients (215 survivors and 105 non-survivors) with confirmed COVID-19 infection were enrolled. After isolation of serum samples, hematological, biochemical, and hormonal parameters were analyzed. Results: The mean age of survivors and non-survivors was 58.92 (SD: 15.28) and 63.65 (SD: 16.62) years, respectively. The results demonstrated significant differences in free triiodothyronine (FT3) [MD (95% CI): 0.40 (0.10, 0.71), P=0.009], total calcium [MD (95% CI): 0.53 (0.21, 0.86), P=0.003], vitamin D [MD (95% CI): 7.72 (6.38, 9.05), P=0.003], erythrocyte sedimentation rate (ESR) [MD (95% CI): 17.09 (9.38, 22.05), P=0.004) and serum ferritin [Median difference: -1091.9, P<0.001), between survivors and non-survivors, respectively. Conclusion: The results revealed that some hematological and endocrine factors play an important role in prognosis of COVID-19 infection. However, further studies with a larger population are required to clarify the exact effects of COVID-19 on the endocrine system.
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Dannikov, Sergey, and Inna Antonova. "HEMATOLOGICAL INDICATORS OF RABBITS AFTER LIFETIME EXPERIMENTAL MODELING OF RETROPERITONEAL HEMATOMA." Agrarian Bulletin of the North Caucasus 51, no. 3 (2023): 16–19. https://doi.org/10.31279/2949-4796-2023-3-51-16-19.
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Lifetime experimental modeling of retroperitoneal hematoma in rabbits can provoke a decrease in the number of blood leukocytes, which is most pronounced in the first day. The average number of leukocytes in the control group ranged from 9.38±0.49 to 10.70±0.80×109/l, and in the experimental group – from 6.36±0.22 to 8.42±0.30×109/l. On the 1st and 3rd days after the experiment, rabbits of the experimental group showed a significant decrease in the number of erythrocytes, hematocrit and hemoglobin levels in the blood, as well as an increase in the average erythrocyte volume, which indicates the formation of regenerative anemia. The average number of erythrocytes in the control group ranged from 4.84±0.15 to 5.23±0.12×1012/l, and in the experimental group – from 3.79±0.04 to 5.33±0.15×1012/l. The level of hematocrit and hemoglobin in the control group ranged from 0.307±0.008 to 0.340±0.008 % and from 103.40±3.97 to 119.80±4.03 g/l, and in the experimental group – from 0.271±0.004 to 0.330±0.005 % and from 87.40±1.72 to 115.80±2.76 g/l, respectively. Reliably large values of the average volume of erythrocytes in the experimental group, compared with the control group, persist up to 14 days, which indicates the presence of active compensatory mechanisms of erythropoiesis. The average value of the erythrocyte volume in the control group ranged from 63.26±0.66 to 64.58±0.45 fl, and in the experimental group it ranged from 65.12±0.45 to 70.64±0.31 fl. There were no significant differences in the number of platelets during the experiment, and their average number in the control and experimental groups ranged from 434.00±44.97 to 501.40±43.23×109/l.
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Malkov, S. V., A. S. Krasnoperov, A. P. Poryvaeva, O. Yu Oparina, I. Yu Vershinina, and M. D. Badov. "HEMATOLOGICAL INDICATORS AND LEUKOCYTE INDICES OF LAYING HENS UNDER TEMPERATURE STRESS." Scientific Notes Kazan Bauman State Academy of Veterinary Medicine 252, no. 4 (2022): 144–55. http://dx.doi.org/10.31588/2413_4201_1883_4_252_144.
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