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1

Ghédira, K., and P. Goetz. "Justicia adhatoda L. (Acanthacées)." Phytothérapie 13, no. 6 (2015): 410–14. http://dx.doi.org/10.1007/s10298-015-1003-6.

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2

Herrmann, A., C. Neumann, and A. Hensel. "Adhatoda vasica - Justicia adhatoda - Alte Arzneipflanze neu entdeckt." Zeitschrift für Phytotherapie 27, no. 6 (2006): 306–10. http://dx.doi.org/10.1055/s-2007-967725.

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3

Ikbal, Abu Md Ashif, Amlanjyoti Rajkhowa, P. Chinglemba Singh, Paromita Dutta Choudhury, and Ram Kumar Sahu. "Assessment of Phytochemical and Anthelmintic Activity of Some Selected Ethnomedicinal Plants from Barak Valley Region of Assam." Biomedical and Pharmacology Journal 13, no. 4 (2020): 1825–31. http://dx.doi.org/10.13005/bpj/2057.

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Since ancient times it has been observed that the ethnomedicinal knowledge is backbone of rural healthcare. The traditional healers of Barak Valley region of Assam used traditional medicine for the treatment of various diseases including helminths infection. Hence the current study was planned to explore the traditional medicines namely Justicia adhatoda, Vernonia amygdalina, Mikania micrantha and Momordica charantia used as anthelmintic activity by the local people of Barak Valley region of Assam. The decoction of leaves of Justicia adhatoda, Vernonia amygdalina, Mikania micrantha and Momordi
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4

Ikbal, Abu Md Ashif, Amlanjyoti Rajkhowa, P. Chinglemba Singh, Paromita Dutta Choudhury, and Ram Kumar Sahu. "Assessment of Phytochemical and Anthelmintic Activity of Some Selected Ethnomedicinal Plants from Barak Valley Region of Assam." Biomedical and Pharmacology Journal 13, no. 4 (2020): 1825–31. http://dx.doi.org/10.13005/bpj/2057.

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Since ancient times it has been observed that the ethnomedicinal knowledge is backbone of rural healthcare. The traditional healers of Barak Valley region of Assam used traditional medicine for the treatment of various diseases including helminths infection. Hence the current study was planned to explore the traditional medicines namely Justicia adhatoda, Vernonia amygdalina, Mikania micrantha and Momordica charantia used as anthelmintic activity by the local people of Barak Valley region of Assam. The decoction of leaves of Justicia adhatoda, Vernonia amygdalina, Mikania micrantha and Momordi
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5

Sai Subhadra Ravali Kompella, Usha Kumary Santha, Thandavan Arthanari Kannan, Kalaiselvi Lakshmanan, and Sridevi Ponnada. "Effect of Vasicine on Kidney Histomorphology in Streptozotocin-Induced Diabetic Wistar Rats." Majalah Biomorfologi 35, no. 1 (2025): 12–20. https://doi.org/10.20473/mbiom.v35i1.2025.12-20.

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Highlights1. Justicia adhatoda leaves can be used as herbal medicine to treat diabetes and its associated conditions. 2. Vasicine in Justicia leaves helps protect kidney health in individuals with diabetes. Background: Justicia adhatoda is a perennial shrub with various potential quinazoline alkaloids viz., vasicine, vasicinone, deoxyvasicine, vasicol, adhatodinine and vasicinol. Objective: The present study aimed to study the effect of vasicine, a quinazoline alkaloid on diabetic nephropathy induced with Streptozotocin in rats. Material and Method: The vasicine was extracted from the leaves o
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6

Balaraman, Gajapathi, V. M. Jerbin Vijay, P. Joanna Gracy, S. Arul Kumar, S. Vishali, and G. Harish. "Exploring the Antibacterial and Antifungal Efficacy of Herbal Plants: An Ayurvedic Research." Journal of Pharmacy and Bioallied Sciences 16, Suppl 5 (2024): S4741—S4745. https://doi.org/10.4103/jpbs.jpbs_884_24.

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ABSTRACT Context: Nature has endowed humanity with a vast repository of remedies that have been use for ages to heal all sorts of ailments. Aim: To evaluate the antibacterial and antifungal efficacy of three herbal plants (Justicia adhatoda, Glycyrrhiza glabra, and Punica granatum), on three microorganisms (Streptococcus mutans, Staphylococcus aureus, and Candida albicans) that are present in the oral stoma. Settings and Design: In vitro microbial study. Methods and Material: Extracts of 0.3 mg/ml, 0.6 mg/ml, 1.25 mg/ml, 2.5 mg/ml, 5.0 mg/ml, and 10.0 mg/ml were prepared from leaves of Justici
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7

Aparna M, Aparna M., Revathy K. V. Revathy K. V, R. Ragunathan R. Ragunathan, and Jesteena Johney Jesteena Johney. "Isolation of Multidrug Resistant Enteric Pathogen from Poultry Fecal Matter and Application of Natural Extract Against the Bacteria." International Journal of Pharmaceutical Science Invention 14, no. 2 (2025): 09–19. https://doi.org/10.35629/6718-14020919.

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This study examined multidrug-resistant (MDR) Enterobacter cloacae isolated from poultry fecal matter alongside evaluation of Justicia adhatoda leaf extract's antibacterial properties for replacing chemical preservatives in poultry feed. Morphological and molecular tests verified the presence of Enterobacter cloacae strain ARMB which demonstrated antibiotic resistance against Penicillin-G, Ampicillin, and Methicillin but retained sensitivity to Chloramphenicol. Tests of antibiotic sensitivity and Hi-Comb analysis confirmed elevated β-lactam antibiotic resistance through plasmid-based resistanc
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8

Prabas, Nand Raut, and Prasanna Purohit Dr. "Antifungal activity shoe by Justicia adhatoda." International Educational Applied Research Journal 08, no. 04 (2024): 7–12. https://doi.org/10.5281/zenodo.11187592.

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Indian medicinal herb Justicia adhatoda L. has long been utilized in Ayurvedic and Unani medicine treatments for respiratory conditions. Throughout the Indian subcontinent, it is widely used. Plant leaves have several well-known pharmacological effects, such as their antibacterial and antifungal characteristics. Two of its main bioactive components, vasicine and vasicinone, have been shown in studies to have antibacterial properties. However, not much has been done to change the direction of research in microbiology. In the current investigation, the plant's potential as a potent antifungal &n
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9

Malathi, Ramaswamy, Dhandapani Kaviyarasan, and Solaimuthu Chandrasekar. "Evaluation of in vitro anti snake venom activity of Justicia adhatoda leaves extract against Russell’s viper snake venom." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 116–22. http://dx.doi.org/10.22270/jddt.v9i4.3116.

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Venomous snake bites possess significant amount of mortality as well as morbidity in tropical and subtropical regions of the world including India. The snake Russell’s viper (Daboia russelii) is responsible for thousands of deaths in India. Although antivenom are the only treatment available and the effects associated with several side effects. As an alternative, plants have been extensively studied in order to obtain an alternative treatment. The uses of plants against the effects of snake bites have been long recognized more scientific attention has been given since last 20 years. Extracts f
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10

Khaladkar, Atharva Sanjay, Amruta Avalaskar, Pranoti Bharati, and Kiran Honkalas. "Formulation and evaluation of Adhulsa lozenges for pediatric patients." Journal of Drug Delivery and Therapeutics 9, no. 2-s (2019): 115–17. http://dx.doi.org/10.22270/jddt.v9i2-s.2601.

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WHO estimates that 235 million people currently suffer from asthma. WHO has recognized herbal medicines as an essential building block for primary health care of vast countries like India. In India the number of children suffering from asthma is increasing. Asthma is the chronic diseases of the bronchi which require continuous medical care. Appropriate management of asthma can enable people to enjoy a good quality of life. Many synthetic and traditional medicines are used in the treatment. Herbal formulations have been used by mankind for the cure and treatment of various diseases and are stil
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11

Rasheed, Faiza. "DETECTION OF BIOACTIVE FRACTIONS OF JUSTICIA ADHATODA L. LEAVES." Canadian Journal of Applied Sciences 3 (2013): 388. http://dx.doi.org/10.21065/19257430.388.3.

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In vitro antibacterial and antioxidant activities of various leaf extracts of Justicia adhatoda L. (locally known as Bhaikar) were assessed. The leaves were also subjected to various phytochemical analysis. Results revealed that leaves of J. adhatoda L. contain significant amount of total alkaloid, phenols flavonoid, saponins, tannins , protein, crude oil, dietary fiber, essential and non essential metal ions. The methanol, ethanol, butanol, chloroform and n-hexane leaf extracts of J
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12

Khan, Md Sirajul Islam, Md Abdul Kaium, Bittam Kumar Sarkar, et al. "Potencies of Justicia adhatoda L. for its possible phytotoxic activity." Plant Science Today 8, no. 2 (2021): 289–92. http://dx.doi.org/10.14719/pst.2021.8.2.1044.

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The phytotoxic effects of Justicia adhatoda L. were investigated on cauliflower, broccoli, tomato, foxtail millet and barnyard grass. The experiments were carried out under laboratory and in pot experiments. Six different aqueous methanol extract concentrations (control, 0.001, 0.003, 0.01, 0.03 and 0.1 g DW equivalent mL-1 extract) were tested in the laboratory and six aqueous extract concentrations (control, 1.0, 2.0, 3.0, 4.0 and 5.0 g DW mL-1 extract equivalent) were evaluated in the pot experiment. Results showed a reduction in germination and growth (shoot length, root length and biomass
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13

Aziz, Khalid, Muhammad Ashraf, Farwa Batool, et al. "Investigation of the Cardio Protective Role of Justicia Adhotoda Leaf Extract Against Isoproterenol-Induced Myocardial Infarction in Rat Model." Scholars Academic Journal of Biosciences 13, no. 03 (2025): 327–34. https://doi.org/10.36347/sajb.2025.v13i03.004.

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Myocardial infarction (MI) continues to be a predominant cause of mortality globally and is characterized by restricted therapeutic alternatives and considerable adverse effects linked to traditional treatments. This study assessed the cardioprotective properties of Justicia adhatoda leaf extract against isoproterenol-induced myocardial infarction in rats at GC, University Faisalabad. A total of 32 albino Wistar rats were randomly allocated into four groups, with one group designated as the control and the remaining groups administered Justicia adhatoda leaf extract (400 mg/kg) or metoprolol (
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14

Omkar, Shelake* Akash Ingale Dr Parag Patil manoj Bachche Rushikesh Lohar Dr. Nilesh Chougule. "Total Phenolics and Flavonoids in Selected Justicia Species." International Journal of Pharmaceutical Sciences 2, no. 11 (2024): 1574–77. https://doi.org/10.5281/zenodo.14237195.

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The phenolics and Flavonoids content of six Justicia species were determined in the present study. The phenolic content was determined using Folin-Ciocalteu assay. The total flavonoids were measured spectrophotometrically using the aluminum chloride colorimetric assay. The results showed that the different parts of selected Justicia species contain significant amount phenolics and flavonoids. The highest phenolic content was showed by leaf of J. adhatoda (38.75 mg GAE) and the least phenolics were observed for root of J. beddomei (22.65 mg GAE). In the case of flavonoids, maximum value was obt
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15

Malathi, R., D. Kaviyarasan, and S. Chandrasekar. "Study on Preliminary Phytochemicals and GC-MS Analysis of Justicia adhatoda Leaves Extract." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 547–50. http://dx.doi.org/10.22270/jddt.v9i4-s.3380.

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Several natural products have been implemented as an alternative health care treatment and in discovery of effective modern drugs. A major focus of natural product chemistry has been toward drug design and discovery. Justicia adhatoda is a well-known Indian medicinal plant valued for its pharmacopeia. This plant root, bark, leaf and flower are used to heal several diseases and poisonous bites. The present work was to evaluate the phytochemicals and GC-MS analysis of J. adhatoda leaves extracts. The extracts were subjected to qualitative phytochemical screening using standard procedures. The re
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16

Praba, A. Angel, P. Christina ruby stella, and A. Nivetha. "In Silico and In Vitro Analysis of Justicia adhatoda Methanol Extract: Molecular Docking Insights and a Promising Approach for Drug Discovery." Oriental Journal Of Chemistry 41, no. 2 (2025): 498–505. https://doi.org/10.13005/ojc/410219.

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Plants are a natural repository for therapeutic compounds. These are practically completely free of adverse effects. For their primary medical requirements, around three-quarters of the world's population turns to traditional medicine, with a significant proportion of these remedies derived from plant-based extracts and bioactive compounds. These phytoconstituents were obtained from various plant sections. This study investigated the antimicrobial activity of methanol extract of Justicia adhatoda against E. coli and S. aureus, demonstrating concentration-dependent inhibition. GC-MS analysis re
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17

C, Harsha, and Rosaline Mary. "The Efficacy of the Leaf Powders of Justicia Adhatoda L. and Leucas Aspera on the Management of the Pulse Beetle Callosobruchus Chinensis L. (Coleoptera: Bruchidae), in Cicer Arietinum L. (Chickpea)." YMER Digital 21, no. 06 (2022): 10–16. http://dx.doi.org/10.37896/ymer21.06/02.

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Insects are a problem in stored grains throughout the world. In India, there are about 200 species of pest insects which cause damage to stored grains and grain products in storage. The stored chickpea seeds are affected by bruchids. The pulse beetle Callosobruchus chinensis is the most widespread and destructive insect pest of economically important leguminous chickpea. The pest control of C. chinensis is very important to protect the loss of nutritive and economic value of chickpea. The present study aimed to protect the stored chickpea seeds from C. chinensis infestation using leaf powders
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18

PRABHUKUMAR, KONICKAL MAMBETTA, FARSANA BEEGAM, SATHEESH GEORGE, and INDIRA BALACHANDRAN. "Revisiting the taxonomy of Justicia beddomei (Acanthaceae)." Phytotaxa 350, no. 1 (2018): 71. http://dx.doi.org/10.11646/phytotaxa.350.1.8.

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Taxonomic history and occurrence of Justicia beddomei in India is discussed. Detailed description, photographs, conservation assessment, ecology and distributional notes are provided along with a comparison of the closely allied species J. adhatoda. The paper also discusses the identity of the raw drug ‘Vasa’ in Indian Systems of Medicine-Ayurveda.
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19

Isha, Pardeep Kumar, and Anand Narain Singh. "An Overview of Justicia adhatoda: A Medicinal Plant but Native Invader in India." Conservation 5, no. 1 (2025): 2. https://doi.org/10.3390/conservation5010002.

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Justicia adhatoda, also known as Adulsa or Vasaka, is a notable member of the family Acanthaceae, with a broad geographic distribution across varied climatic conditions, and is known for its extensive medicinal properties for treating respiratory disorders, tuberculosis, malaria, and dysentery. It possesses several pharmacological activities, including anti-bacterial, anti-fungal, and anti-cancerous ones. In addition to discussing its morphology, phytochemistry, and pharmacological aspects, the present review also focuses on its several unexplored facets, such as pollination mechanism, cytolog
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20

Dash, Chandan Kumar, Sheikh Shamimul Alam, and Syeda Sharmeen Sultana. "Karyomorphology of Justicia adhatoda L. by differential staining." Dhaka University Journal of Biological Sciences 27, no. 2 (2018): 175–81. http://dx.doi.org/10.3329/dujbs.v27i2.46466.

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Karyomorphological features of Justicia adhatoda L. were investigated in this study after differential staining with orcein, CMA and DAPI for proper characterization. In this species "Simple Chromocenter Type" of interphase nuclei was observed with many small heterochromatin blocks after orcein staining. Prophase chromosomes showed "Interstitial Type" of staining pattern which indicated the tendency of aggregation of heterochromatin in interstitial regions of chromosome. This species was found to possess 2n = 34 metacentric chromosomes. The total length of 2n chromosome complement was 132.17 μ
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Prabas, Nand Raut, and Prasanna Purohit Dr. "Antibacterial activity of important medicinal plant Justicia adhatoda." International Educational Applied Research Journal 08, no. 04 (2024): 1–6. https://doi.org/10.5281/zenodo.11187571.

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Justicia adhatoda L., an Indian medicinal herb, has long been used in Unani and Ayurvedic medicine treatments for respiratory ailments. It is widespread in the Indian subcontinent. There are numerous well-known pharmacological effects of plant leaves, including their antifungal and antibacterial properties. Studies have highlighted the antibacterial qualities of vasicine and vasicinone, two of its primary bioactive ingredients. Nevertheless, not much has been done to shift the focus of microbiology activities. In the current investigation, the plant's potential as a potent and antibacterial ag
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22

Mahajan, Munisha, Sanjeev Kumar, Jyoti Gaur, et al. "Green synthesis of ZnO nanoparticles using Justicia adhatoda for photocatalytic degradation of malachite green and reduction of 4-nitrophenol." RSC Advances 15, no. 4 (2025): 2958–80. https://doi.org/10.1039/d4ra08632e.

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Green synthesis of ultra-small ZnO nanoparticles (5.2/12.41 nm) using Justicia adhatoda leaf extract. Exceptional photocatalytic degradation of malachite green (99.8%) and reduction of 4-nitrophenol under UV/sunlight. Eco-friendly water remediation.
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Oli, Biraj, Gyanendra Ghimire, Bijay Dhakal, Neetu Amatya, Deepjyoti Adhikari, and Netra Lal Bhandari. "Comparative Phytochemical and Biological Study of Tinospora cordifolia (Thunb.) Miers and Justicia adhatoda L. Plants Collected from West Rukum of Nepal." Journal of Nepal Chemical Society 43, no. 2 (2023): 91–102. http://dx.doi.org/10.3126/jncs.v43i2.53348.

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Medicinal plants contained an impressive number of modern drugs and are believed to be a precious natural reservoir that has been continuously studied for its pharmacological activities against various ailments. Tinospora cordifolia and Justicia adhatoda are widely used shrubs in folk and ayurvedic systems of medicine. Phytochemical screening of different fractions of the extract of the bark of T. cordifolia and leaf, stem, and flowers of J. adhatoda was done and results show the presence of alkaloids, flavonoids, phenolics, glycosides, terpenoids in both plants. The antibacterial potency of m
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Mahajan, Munisha, Sanjeev Kumar, Jyoti Gaur, et al. "Correction: Green synthesis of ZnO nanoparticles using Justicia adhatoda for photocatalytic degradation of malachite green and reduction of 4-nitrophenol." RSC Advances 15, no. 10 (2025): 7843. https://doi.org/10.1039/d5ra90020d.

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Correction for ‘Green synthesis of ZnO nanoparticles using Justicia adhatoda for photocatalytic degradation of malachite green and reduction of 4-nitrophenol’ by Munisha Mahajan et al., RSC Adv., 2025, 15, 2958–2980, https://doi.org/10.1039/D4RA08632E.
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25

Pushkala, V. Poorna, H. Subhashree, and K. Yazhini. "In-Silico Screening of Phytocompounds of Justicia Adhatoda for Thrombolytic Activity." International Journal of Membrane Science and Technology 10, no. 4 (2023): 2322–29. http://dx.doi.org/10.15379/ijmst.v10i4.2414.

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Background: The risk of thrombosis and its associated mortality is becoming a greater public health concern in both industrialized and developing nations. Clinical condition that is myocardial infarction, ischemic stroke, unstable angina, peripheral vascular diseases like deep vein thrombosis prioritise top in the list of thrombotic disorders. Conventional thrombolytic medications including alteplase, anistreplase, streptokinase and urokinase offer life risking adverse effects like haemorrhage, stroke, vascular dysfunction, hypertension, internal bleeding and so on. In order to overcome the un
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Gutti, Usha, Jaswant Kumar Komati, Aneesh Kotipalli, Raja Gopal Venakata Saladi, and Ravi Kumar Gutti. "Justicia adhatoda induces megakaryocyte differentiation through mitochondrial ROS generation." Phytomedicine 43 (April 2018): 135–39. http://dx.doi.org/10.1016/j.phymed.2018.04.038.

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27

Berry, Eapsa, Ashish Kumar Choudhary, Girish Mishra, Rajesh Tandon, and R. Geeta. "Justicia adhatoda reveals two morphotypes with possible functional significance." Journal of Plant Research 133, no. 6 (2020): 783–805. http://dx.doi.org/10.1007/s10265-020-01224-w.

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28

Sukhdeep Kaur, Deepika Verma, Sourav Kumar, et al. "Extraction of eco-friendly natural dyes from Justicia adhatoda leaves and their application on wool and silk fabrics." International Journal of Science and Research Archive 15, no. 3 (2025): 464–73. https://doi.org/10.30574/ijsra.2025.15.3.1497.

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Natural dyes are widely used for textile industries, due to their harmless effects and harmful consequences of synthetic dyes. Natural dyes work on cotton, silk and wool etc. In this article, the leaves of Justicia adhatoda are used as a colorant for dyeing of wool and silk fabrics. Various extracts (aqueous, butanol, chloroform and hexane) of Justicia adhatoda leaves have been prepared and investigated. The obtained dyes yield a variety of shades and are processed with mordants such as alum and copper sulphate. From the K/S values, it is found that hexane extracted dye generated maximum color
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Selvaraj, Jayaraman. "Molecular docking data of E3 ubiquitin-protein ligase WWP1 with compounds from a medicinal plant Justicia adhatoda L." Bioinformation 17, no. 1 (2021): 162–66. http://dx.doi.org/10.6026/97320630017162.

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It is known that E3 ubiquitin-protein ligase WWP1 is linked to oral cancer. Therefore, it is of interest to document molecular docking data of E3 ubiquitin-protein ligase WWP1 with compounds ((Stigmasterol, Pyrazinamide, Vasicinone and Ethambutol)) from a medicinal plant Justicia adhatoda L for further consideration
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Selvaraj, Jayaraman. "Molecular modeling of cornulin (CRNN) for docking with phytocompounds from Justicia adhatoda L." Bioinformation 17, no. 1 (2021): 200–205. http://dx.doi.org/10.6026/97320630017200.

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Cornulin (CRNN) is linked with tumour progression. Therefore, it is of interest to document data on the molecular modeling of cornulin (CRNN) for docking with phytocompounds (Pyrazinamide, Anisotine, Vasicinone, Vasicoline) from Justicia adhatoda L. Thus, we document the optimal binding features of these compounds with the cornulin model for further consideration
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Roshan Kumar Mehta, Rupkala Thapa, and Mukesh Kumar Chaudhary. "Evaluation of anti-diabetic activity of Justicia adhatoda (Linn.) Leaves in diabetic wistar rats." Journal of Universal College of Medical Sciences 11, no. 01 (2023): 50–54. http://dx.doi.org/10.3126/jucms.v11i01.54641.

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INTRODUCTION Diabetes mellitus is defined as the increase in blood glucose level resulting from defects in insulin secretion, insulin action, or both. The present study was conducted to evaluate anti-diabetic activity of Justicia adhatoda (Linn.) leaves extract in diabetic Wistar rats. Justicia adhatoda, commonly known as vasaka is rich in phytochemicals like alkaloids, saponins, steroids, flavonoids and glycosides. It is used in asthma, jaundice, wound healing, typhus fever, cough, chronic bronchitis and inflamma- tory swellings treatment. MATERIAL AND METHODS The extract was obtained by macerat
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Rao, Rajneesh, Sanyogita Kumari, and Ashok Kumar. "Evaluation of chemically characterized Ocimum tenuiflorum L. essential oil as phytopreservative against fungal deterioration of Justicia adhatoda L. raw materials during storage." International Journal of Current Microbiology and Applied Sciences 13, no. 8 (2024): 132–45. https://doi.org/10.20546/ijcmas.2024.1308.017.

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The stored herbal raw materials (HRMs) of Justicia adhatoda were found associated with spores of various storage fungi in which Cladosporium cladosporioides exhibited the highest relative density (25.02%) followed by Aspergillus flavus (22.49%) and A. niger (21.46%). The chemical composition of Ocimum tenuiflorum essential oil (OtEO) showed 41 considerable peaks. Eugenol (61.30%) was found as major component followed by β- Caryophyllene (11.89%), Germacrene D (9.14%), α- Cubebene (2.54%) and Carvacrol (2.04%). OtEO showed broad spectrum fungitoxicity and MIC against A. flavus DDUGU-07 was reco
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Pole, R. P. Praveen, A. Doss, S. Alwin David, N. Ahamed Kabir, and S. Satheesh. "Green synthesis of MnO2 nanoparticles using Justicia adhatoda leaf extract." Sustainable Chemistry One World 7 (September 2025): 100072. https://doi.org/10.1016/j.scowo.2025.100072.

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34

Samej, Kute* Abhishek Kotkar Dr. Jha Urmilesh Dr. Mansuk A. G. Navale S. U. "Adulsa (Justicia Adhatoda): its Medicinal Properties, Uses, and Pharmacological Potential." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 476–82. https://doi.org/10.5281/zenodo.15140746.

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Adulsa (Justicia adhatoda), commonly known as Malabar nut or Vasaka, is a highly valued medicinal plant widely used in traditional medicine systems such as Ayurveda, Unani, and Siddha. This review article aims to provide an exhaustive overview of its phytochemical composition, traditional uses, pharmacological properties, and potential therapeutic applications. The plant is particularly renowned for its efficacy in treating respiratory disorders, including asthma, bronchitis, and chronic obstructive pulmonary disease (COPD). Additionally, Adulsa exhibits anti-inflammatory, antimicrobial, and a
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35

Chowbey, Anita, and Farha Rehman. "Impact of Nickel and Lead Exposure on the Phytochemical Composition and Bioactive Compounds of Justicia Adhatoda Leaves." Journal of Neonatal Surgery 14, no. 8S (2025): 300–308. https://doi.org/10.52783/jns.v14.2542.

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This study investigates the impact of heavy metals, specifically nickel and lead, on the yield, phytochemical composition, and bioactive compound content of Justicia adhatoda leaves. The plant extracts were subjected to hydroalcoholic and petroleum ether extraction methods, and the yield was assessed after treatment with different concentrations of nickel and lead (50mg, 100mg, 150mg) for 45 days. The phytochemical analysis revealed that flavonoids, phenols, saponins, and alkaloids were present in the control group, with changes observed after metal exposure. The total flavonoid content (TFC)
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Carneiro, Marcos Rodrigo Beltrão, Lóide Oliveira Sallum, José Luís Rodrigues Martins, Josana de Castro Peixoto, Hamilton Barbosa Napolitano, and Lucimar Pinheiro Rosseto. "Overview of the Justicia Genus: Insights into Its Chemical Diversity and Biological Potential." Molecules 28, no. 3 (2023): 1190. http://dx.doi.org/10.3390/molecules28031190.

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The genus Justicia has more than 600 species distributed in both hemispheres, in the tropics and temperate regions, and it is used in the treatment of numerous pathologies. This study presents a review of the biological activities of plant extracts and isolated chemical constituents of Justicia (ACANTHACEAE), identified in the period from May 2011 to August 2022. We analyzed over 176 articles with various biological activities and chemical compound descriptions present in the 29 species of Justicia. These have a variety of applications, such as antioxidant and antimicrobial, with alkaloids and
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More, Deepak B., and Ravi P. Patil. "Phytochemical profile of Justicia adhatoda L. and Justicia betonica L. (Acanthaceae) leaf extracts by GC-MS." Journal of Pharmacognosy and Phytochemistry 14, no. 3 (2025): 386–87. https://doi.org/10.22271/phyto.2025.v14.i3e.15390.

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Arvinder, Kaur, Kaur Davinder, and Arora Saroj. "Evaluation of antioxidant and antimutagenic potential of Justicia adhatoda leaves extract." African Journal of Biotechnology 14, no. 21 (2015): 1807–19. http://dx.doi.org/10.5897/ajb2015.14486.

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Uddin, Mohammed Sala, and Mohammad Harun Ur Rashid. "Effects of auxins on the stem cuttings of Justicia Adhatoda L." Bangladesh Journal of Botany 52, no. 3 (2023): 861–65. http://dx.doi.org/10.3329/bjb.v52i3.68947.

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Justicia adhatoda L. (Bashak) is an evergreen, medicinal shrub belongs to the family Acanthaceae. The seeds germination quality of the species is very poor. The effects of auxins viz. IAA, IBA and NAA on the stem cuttings of the plant were assessed. A total of 13 treatments were applied on the stem cuttings and planted in sandy bed following completely randomized design. Results revealed that the maximum number of roots (28.67), length of roots (14.10 cm) and biomass (12.78g) were obtained at 90 days after planting in the cuttings treated with IBA 1000 ppm solution. Whereas, number of roots (2
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KSS, Ravali, Usha Kumary S, Sarathchandra G, Kannan TA, Parthiban M, and Kalaiselvi L. "Vasicine a quinazoline alkaloid from Justicia adhatoda L.: Its antioxidant property." International Journal of Advanced Biochemistry Research 8, no. 1S (2024): 729–31. http://dx.doi.org/10.33545/26174693.2024.v8.i1sj.415.

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RAUT, Ninad B., Umeshkumar L. TIWARI, Bhupendra S. ADHIKARI, Gopal S. RAWAT, and Srikant CHANDOLA. "Population Status of Commercially Important Medicinal Plants in Dehradun Forest Division, Uttarakhand (India)." Notulae Scientia Biologicae 5, no. 2 (2013): 175–82. http://dx.doi.org/10.15835/nsb528299.

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The objective of forest management in the tropics, in recent decades, has shifted from timber production to biodiversity conservation and maintenance of life support system. However, past forestry practices have greatly influenced the structure of plant communities, preponderance of foreign invasive species, populations of high value medicinal plants as well as other non-wood forest products. We assessed the abundance and distribution of medicinal plants in managed and undisturbed forests of Dehradun Forest Division (DFD), Uttarakhand (India). A total of 80 transects (each 1 km long) were laid
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Kumar Shrestha, Deepak, Basanta Kumar Sapkota, and Krishna Prasad Sharma. "Assessment of Phytochemicals, Antioxidant Activity, Total Phenolic and Flavonoid Contents of Selected Nepalese Medicinal Plants." Nepal Journal of Biotechnology 10, no. 2 (2022): 45–51. http://dx.doi.org/10.54796/njb.v10i2.239.

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Several medicinal plants have been used from the traditional period of times to cure different diseases but there is little scientific evidence. The phytochemicals of plants can reduce cardiovascular and other diseases. The present study analyzed the five different medicinal plants of the Gulmi and Rupandehi districts of Nepal using in vitro studies. They were Crateva Unilocularis, Aegle marmelos, Nyctanthes arbor-tristis, Urtica dioica and Justicia adhatoda. The antioxidant potential of the methanolic extract of plants was evaluated by DPPH radical scavenging assay, total phenolic content was
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Kumar, Sonu, Rajveer Singh, Debrupa Dutta, et al. "In Vitro Anticancer Activity of Methanolic Extract of Justicia adhatoda Leaves with Special Emphasis on Human Breast Cancer Cell Line." Molecules 27, no. 23 (2022): 8222. http://dx.doi.org/10.3390/molecules27238222.

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Natural products are being targeted as alternative anticancer agents due to their non-toxic and safe nature. The present study was conducted to explore the in vitro anticancer potential of Justicia adhatoda (J. adhatoda) leaf extract. The methanolic leaf extract was prepared, and the phytochemicals and antioxidant potential were determined by LCMS analysis and DPPH radical scavenging assay, respectively. A docking study performed with five major alkaloidal phytoconstituents showed that they had a good binding affinity towards the active site of NF-κB. Cell viability assay was carried out in fi
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Gautam, Susmita, Subodh Khanal, Dipak Khanal, Saroj Raj Mishra, and Sunil Ghimire. "Phytochemical Screening of Selected Botanicals and their Effectiveness Against Maize Weevil (Sitophilus Zeamais Motsch.) at Paklihawa, Rupandehi, Nepal." Advanced Journal of Graduate Research 11, no. 1 (2021): 34–44. http://dx.doi.org/10.21467/ajgr.11.1.34-44.

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Laboratory experiment was done to perform the phytochemical screening of six locally available botanicals (Azadirachta indica Juss, Artemisia dubia Wall, Lantana camara L, Parthenium hysterophorus L, Justicia adhatoda Linn. and Moringa oleifera L.) and their effectiveness to control the maize weevil (Sitophilus zeamais Motsch.) at Agriecology lab of Institute of Agriculture and Animal Science, Paklihawa Campus, Rupandehi, Nepal. Seven treatments (leaf extract of A. indica, A. dubia, L. camara, P. hysterophorus. J. adhatoda and M. oleifera and distilled water as control) applied at 3 different
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Devkota, Anjana, and Swasti Sharma. "Allelopathic Potential of Medicinal Plants: Costus speciosus Koen ex. Retz and Justicia adhatoda Linn." Journal of Natural History Museum 28 (December 19, 2015): 57–65. http://dx.doi.org/10.3126/jnhm.v28i0.14168.

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The study was carried out to evaluate the allelopathic effect of aqueous extract of rhizome and leaves of Costus speciosus Koen ex. Retz and Justicia adhatoda Linn. respectively on germination and growth of wheat (Triticum aestivum Linn.) and pea (Pisum sativum Linn.). Effect was assessed by recording their effects on germination and percentage growth of root and hypocotyle of test plants. However, the extent of inhibitory and stimulatory effect of extracts varied with the plant species. The extract reduced the germination of the test seeds. However, root and hypocotyle elongations of wheat an
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PAUL, Annika Maria, and Anish NAG. "Phytochemical fingerprinting and evaluation of in silico anti-thrombotic properties of Justicia adhatoda L. and Cordia dichotoma Frost." Notulae Scientia Biologicae 15, no. 3 (2023): 11625. http://dx.doi.org/10.55779/nsb15311625.

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The study aimed to characterize hydro-methanolic (25%) extracts of Justicia adhatoda L. (stem and flower) and Cordia dichotoma Frost. (Stem and fruit) and evaluate the in silico thrombolytic properties of the major phytocompounds present in the plants. In the preliminary fluorescence imaging through treatment by different reagents, both plants were found to be pharmacologically active. Further qualitative screening of phytochemicals, spectroscopy-based techniques, namely, UV-Vis Spectroscopy and FTIR, revealed various classes of compounds such as polyacetylenes, aglycones, quercetin, anthocyan
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Karthika, V., V. Ramya, V. Kalaiselvi, and S. Shanmathi. "Synthesis and Characterization of Zinc Oxide Nanoparticles Using Justicia Adhatoda Leaf Extract." International Journal of Advanced Science and Engineering 7, no. 3 (2021): 1839–42. http://dx.doi.org/10.29294/ijase.7.3.2021.1839-1842.

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Jose, Anju Betty, Deepali, Malsawmtluangi, Nitasha Priscilla, Rashmi, and Dileep Francis. "Antimicrobial, antioxidant, and anti-inflammatory activities of Justicia adhatoda L. leaf extract." Medicinal Plants - International Journal of Phytomedicines and Related Industries 15, no. 3 (2023): 595–604. http://dx.doi.org/10.5958/0975-6892.2023.00060.6.

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Choudhary, Shailja, Hemlata Kaurav, and Gitika Chaudhary. "ADHATODA VASICA (VASAPATRA): A REVIEW BASED UPON ITS MEDICINAL PROPERTIES." International Journal of Research in Ayurveda and Pharmacy 12, no. 3 (2021): 79–87. http://dx.doi.org/10.7897/2277-4343.120379.

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Adhatoda vasica (L.) Nees is also known as Justicia adhatoda L. belongs to the family Acanthaceae and is considered the most significant plant in the world. It is commonly known as Vasaka, Vasica, Adosa, Malbur nut and is distributed in various regions of India and throughout the world. It is a well-known plant in Ayurveda and Unani medicinal system. This plant has been used in the indigenous medicinal system of India for more than 2000 years. The plant has great medicinal importance and is used to treat various diseases and disorders mainly respiratory tract diseases like cough, symptoms of c
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Khandagale, Sandip Suresh* Mahalkar Ram Babasaheb Madane Somnath Jotiram Patil Onkar Ganpat Dabhade Sakshi kailasrao Salve Dvitiya Shantilal. "To Study The Preparation Formulation and Evaluation of Medicated Lolipop." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 1275–91. https://doi.org/10.5281/zenodo.11264459.

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Adhatoda vasica (L.) Nees is also known as Justicia adhatoda L. belongs to the family Acanthaceae and is considered the most significant plant in the world. It is commonly known as Vasaka, Vasica, Adosa, Malbur nut and is distributed in various regions of India and throughout the world. It is a wellknown plant in Ayurveda and Unani medicinal system. This plant has been used in the indigenous medicinal system of India for more than 2000 years. The plant has great medicinal importance and is used to treat various diseases and disorders mainly respiratory tract diseases like cough, symptoms of co
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