Log in

Relevant bibliographies by topics / And Sodium starch glycolate / Journal articles

To see the other types of publications on this topic, follow the link: And Sodium starch glycolate.

Journal articles on the topic 'And Sodium starch glycolate'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'And Sodium starch glycolate.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Putra, Okta Nama, Ida Musfiroh, Sarah Elisa, et al. "Sodium Starch Glycolate (SSG) from Sago Starch (Metroxylon sago) as a Superdisintegrant: Synthesis and Characterization." Molecules 29, no. 1 (2023): 151. http://dx.doi.org/10.3390/molecules29010151.

Full text

Abstract:

The characteristics of sago starch exhibit remarkable resemblances to those of cassava, potato, and maize starches. This review intends to discuss and summarize the synthesis and characterization of sodium starch glycolate (SSG) from sago starch as a superdisintegrant from published journals using keywords in PubMed, Scopus, and ScienceDirect databases by Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020). There are many methods for synthesizing sodium starch glycolate (SSG). Other methods may include the aqueous, extrusion, organic solvent slurry, and dry methods

APA, Harvard, Vancouver, ISO, and other styles

2

K., Rekha Rani Y. Navya Reddy R. Mohana Priya G.Anusha and T. Spurthi. "FORMULATION AND EVALUATION OF ORAL DISINTEGRATION TABLETS OF OMEPRAZOLE." indo American Journal of Pharmaceutical Sciences 04, no. 05 (2017): 1391–97. https://doi.org/10.5281/zenodo.804918.

Full text

Abstract:

Omeprazole fast disintegrating tablets were prepared by using different superdisintegrants like crospovidone, croscarmellose sodium and Sodium starch glycolate by direct compression. Precompression parameters were conducted for all formulations blend and were found to be satisfactory. The prepared tablets were evaluated for various parameters like content uniformity, hardness, friability, wetting time, water absorption ratio, disintegration time and In-vitro dissolution. The results indicated that the tablets complied with the official specifications. The disintegration studies shown that the

APA, Harvard, Vancouver, ISO, and other styles

3

Shahidulla, SM, and Tayyaba Jeelani. "Formulation and In-Vitro Evaluation of Taste Masked Fast Disintegrating Tablets of Labetalol Hydrochloride by Wet Granulation Technique." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 442–49. http://dx.doi.org/10.22270/jddt.v9i4-a.3506.

Full text

Abstract:

Labetalol Hydrochloride is a β-blocker generally indicated for the treatment of hypertension, and it is extensively metabolized due to the hepatic metabolism. In the present work, an attempt was made to mask the taste by Solid Dispersion technique, with a formulation into Fast Disintegrating dosage form, using superdisintegrants such as Cross carmellose sodium (CCS), crospovidone (CP) and sodium starch glycolate (SSG). The complexes of Labetalol hydrochloride with HP-β-CD (1:3 ratio) were prepared by Co-precipitation method. Using the drug HP-β-CD complex, Fast Disintegrating tablets were prep

APA, Harvard, Vancouver, ISO, and other styles

4

Karim, S., A. Biswas, A. Bosu, F. R. Laboni, A. S. Julie, and M. H. O. Rashid. "Effect of Sodium Starch Glycolate on Formulation of Fexofenadine Hydrochloride Immediate Release Tablets by Direct Compression Method." Journal of Scientific Research 10, no. 1 (2018): 31–38. http://dx.doi.org/10.3329/jsr.v10i1.32703.

Full text

Abstract:

Present study aspires at the design of an immediate release formulation with prospective use of fexofenadine hydrochloride by exploring the effect of sodium starch glycolate as super disintegrant. Fexofenadine hydrochloride immediate release tablets (Formulations F-1, F-2, F-3, F-4 and F-5) using different ratios of sodium starch glycolate as a disintegrant were prepared by direct compression method. Standard physicochemical tests were performed for all the formulations. Dissolution studies of the formulations were done in phosphate buffer, pH 6.8 using USP apparatus II (paddle apparatus) at 5

APA, Harvard, Vancouver, ISO, and other styles

5

Polishetty, Saipriya* Mariyam Suryaprakash Reddy SK. Irfan Khan Afshan Urooj Dr. Y. Krishna Reddy Dr.K. N. V. Rao Dr. K. Rajeswar Dutt. "FORMULATION, OPTIMIZATION AND EVALUATION OF ESLICARBAZEPINE ACETATE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1688–93. https://doi.org/10.5281/zenodo.1209355.

Full text

Abstract:

The present study aims at developing an Eslicarbazepine fast dissolving tablet formulation for the effctive treatment of Epilepsy. To provide the patient with the most convenient mode of administration, FDT’s will dissolve quickly. A Eslicarbazepine is absorbed to atleast 90% from the gut, independently of food intake. It is quickly metabolized to esclicarbazepine. So the present work was aimed at formulating fast dissolving tablet for Eslicarbazepine, total 6 formulations were developed by using synthetic superdisintigrants like cross caramellose sodium, Crosspovidone, sodium starch gly

APA, Harvard, Vancouver, ISO, and other styles

6

Zulfikar, Muhaini, Arisanty Arisanty, and Sisilia Tresia Rosmala Dewi. "Formulasi Fast Disintegrating Tablet Ekstrak Rimpang Kunyit (Curcuma domestica) dan Perasan Umbi Kentang (Solanum tuberosum L)." Journal of Experimental and Clinical Pharmacy (JECP) 3, no. 2 (2023): 88. http://dx.doi.org/10.52365/jecp.v3i2.483.

Full text

Abstract:

Fast Disintegrating Tablet (FDT) merupakan tablet yang dapat dipecah dalam waktu kurang dari 60 detik saat diletakkan di atas lidah dengan jumlah air yang minimal. Kunyit dan kentang digunakan untuk menurunkan kadar asam dalam lambung yang bertujuan untuk mengobati pasien penderita gastritis. Tujuan penelitian ini membuat formulasi FDT rimpang kunyit (Curcuma domestica) dan perasan umbi kentang (Solanum tuberosum L) dengan variasi konsentrasi sodium starch glycolate sebagai bahan penghancur yaitu formula I (2%), formula II (3%) dan formula III (4%). Penelitian dilakukan dengan metode observasi

APA, Harvard, Vancouver, ISO, and other styles

7

Obaidat, Aiman, та Rana Obaidat. "Development and evaluation of fast-dissolving tablets of meloxicam-β-cyclodextrin complex prepared by direct compression". Acta Pharmaceutica 61, № 1 (2011): 83–91. http://dx.doi.org/10.2478/v10007-011-0005-7.

Full text

Abstract:

Development and evaluation of fast-dissolving tablets of meloxicam-β-cyclodextrin complex prepared by direct compressionThe aim of this study was to prepare fast-dissolving tablets of meloxicam after its complexation with β-cyclodextrin (β-CD) and to investigate the effect of using different superdisintegrants on the disintegration and release of meloxicam from the tablets. A complex of meloxicam with β-CD was prepared by spray drying and then compressed in the form of tablets utilizing the direct compression technique. Three superdisintegrants were employed at various levels - sodium starch g

APA, Harvard, Vancouver, ISO, and other styles

8

Parfati, Nani, Karina Citra Rani, Nathanael Charles та Valencia Geovany. "PREPARATION AND EVALUATION OF ATENOLOL-β-CYCLODEXTRIN ORALLY DISINTEGRATING TABLETS USING CO-PROCESS CROSPOVIDONE-SODIUM STARCH GLYCOLATE". International Journal of Applied Pharmaceutics 10, № 5 (2018): 190. http://dx.doi.org/10.22159/ijap.2018v10i5.27982.

Full text

Abstract:

Objective: The aim of this current research was to formulate and analyze the characteristics of atenolol-β-cyclodextrin which using co-process crospovidone-sodium starch glycolate as the disintegrants. Evaluation which has been conducted on orally disintegrating tablets consist of wetting time, water absorption ratio, in vitro dispersion time, and dissolution.Methods: Inclusion complex of atenolol-β-cyclodextrin which were prepared using solvent evaporation method, then formulated using co-processed crospovidone-sodium starch glycolate 1:1 (formula 1) and 1:2 (formula 2) into orally disintegra

APA, Harvard, Vancouver, ISO, and other styles

9

Setyawan, Dwi, Widji Soeratri, Mahrus Naufal Nuruddin, Diajeng Putri Paramita, and Bambang Widjaja. "Optimization of Povidone K-30 and Sodium Starch Glycolate on Levofloxacin Tablet by Factorial Design." Jurnal ILMU DASAR 21, no. 1 (2020): 35. http://dx.doi.org/10.19184/jid.v21i1.10220.

Full text

Abstract:

The aim of this study was to determine the effect of binder and disintegrant excipients toward tablet properties of levofloxacin as the latter tends to suffer brittle fracture upon compression. The excipients used were povidone K-30 as the binder and sodium starch glycolate (SSG) as the disintegrant which the tablets were formulated according to factorial design 22 with two factors and two levels on each factor. Four formulas were prepared by wet granulation method using 2 and 4% of each povidone K-30 and sodium starch glycolate in various compositions. Tablet properties were evaluated for its

APA, Harvard, Vancouver, ISO, and other styles

10

Sujit, S. Shinde* Madan k. Shinde Avinash A. Bhagat Sachitanand Balaji Biradar. "Formulation And Evaluation Of Fast Dissolving Sodium Diclofenac Sodium Tablet." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 1761–74. https://doi.org/10.5281/zenodo.11400826.

Full text

Abstract:

The present study was aimed to formulate, evaluate, and optimize a tablet that disintegrates and dissolved rapidly toshow a rapid onset action. Diclofenac sodium, non-steroidal- inflammatory, analgesic, and pyretic properties were selected asa model drug. Diclofenac sodium is among the most extensivelyused Non-steroidal anti-inflammatory drugs, employed inmucosal skeletal complaints, especially arthritis. In the present study, an attempt has been made to prepare fast dissolvingtablets of diclofenac sodium using super disintegrants like sodium starch Glycolate, Croscarmellose sodium, Crospovido

APA, Harvard, Vancouver, ISO, and other styles

11

Nitalikar, Manoj M., and Dinesh M. Sakarkar. "Formulation development and characterization of fast disintegrating tablets of Nimesulide." Stamford Journal of Pharmaceutical Sciences 4, no. 2 (2012): 25–28. http://dx.doi.org/10.3329/sjps.v4i2.10436.

Full text

Abstract:

An attempt was made to prepare fast dissolving tablets of anti-inflammatory drug Nimesulide preparing by direct compression method. The superdisintegrants Cross-carmellose and Sodium starch glycolate were used in different concentrations. Twelve formulations using those superdisintegrants at different concentration levels were prepared to access their efficiency and critical concentration level. Different evaluation parameters for tablet were studied. Tablets containing Cross-carmellose showed superior organoleptic properties and excellent in-vitro drug release as compared to other formulation

APA, Harvard, Vancouver, ISO, and other styles

12

Choudhury, Priyanka, Pulak Deb, and Suvakanta Dash. "FORMULATION AND STATISTICAL OPTIMIZATION OF BILAYER SUBLINGUAL TABLETS OF LEVOCETIRIZINE HYDROCHLORIDE AND AMBROXOL HYDROCHLORIDE." Asian Journal of Pharmaceutical and Clinical Research 9, no. 5 (2016): 228. http://dx.doi.org/10.22159/ajpcr.2016.v9i5.13343.

Full text

Abstract:

ABSTRACTObjective: The aim of the present study is to formulate and optimize bilayer sublingual tablets of Levocetrizine hydrochloride and Ambroxolhydrochloride using a 2 response surface methodology employing design expert-10.0. Sodium starch glycolate and Camphor were selected asindependent variables while disintegration time (sec) and water absorption ratio (%) were considered as responses. 3Methods: The bilayer sublingual tablets were prepared by direct compression and evaluated for various evaluation parameters including hardness,thickness, friability, drug content uniformity, wetting tim

APA, Harvard, Vancouver, ISO, and other styles

13

Noma, S. T., B. A. Tytler, A. K. Olowosulu, and Z. S. Yahaya. "Evaluation of the disintegrant property of co-processed sorghum starch-silicon dioxide excipient in chlorpheniramine orodispersible tablets." Journal of Basic and Social Pharmacy Research 1, no. 3 (2020): 1–10. http://dx.doi.org/10.52968/27452073.

Full text

Abstract:

Background: Fast dissolving or orodispersible tablets are highly desirablein groups such as children, uncooperative, nauseated, or those on reduced water intake to ease the difficulties associated with swallowing the conventional solid dosage forms. Objectives: The work aimed to evaluate the disintegrant property of sorghum starch-silicon dioxide co-processed mixture in the formulation of chlorpheniramine orodispersible tablets. Method: Different batches of orodispersible tablets of chlorpheniramine maleate (4 mg) were prepared by direct compression method using Avicel® as a bulking agent and

APA, Harvard, Vancouver, ISO, and other styles

14

Mengesha, Yohannes, Anteneh Belete, and Tsige Gebre-Mariam. "Preparation and Characterization of Carboxymethylated and Cross-Linked Enset Starch as a Disintegrant in Tablets." Ethiopian Pharmaceutical Journal 35, no. 2 (2020): 119–34. http://dx.doi.org/10.4314/epj.v35i2.5.

Full text

Abstract:

Starch and modified starches have been commonly employed as excipient in pharmaceutical industry. The use of non-modified or “native” starch, However, is mostly confined due to limitation in several physicochemical properties. Cross-linked sodium carboxymethyl starch which is also known as sodium starch glycolate is extensively used in fast dissolving tablets to disperse the drugs within short span of time. In this study, enset starch was carboxymethylated and subsequently cross-linked. Carboxymethyl enset starch (CMES) was obtained by reacting enset starch and monochloroacetic acid (MCA) in t

APA, Harvard, Vancouver, ISO, and other styles

15

Chandrasekar, R., Prudhvi Raj V, and Sameer Shaik. "Formulation Development and Invitro Evaluation of Gliclazide Pellets using Superdisintegrants by Extrusion Spheronization Technique." International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN) 16, no. 1 (2023): 6266–80. http://dx.doi.org/10.37285/ijpsn.2023.16.1.2.

Full text

Abstract:

Introduction: Gliclazide is a sulfonylurea derivative used for the treatment of type 2 Diabetes, it is an anti-diabetic drug it is marketed under the brand name Diamicron. It is taken orally and used when dietary changes, lack of exercise, and weight loss are not sufficient.  Aim: The principal objective of this work was to develop, formulate and evaluate the pellet formulations prepared with the incorporation of different super disintegrants in different ratios and in different combinations. In this research work, the drug gliclazide was chosen as a model drug and it was formulated into

APA, Harvard, Vancouver, ISO, and other styles

16

Raina, Binu, Birendra C. Shrivastava, Anurag Bhargava, Shailesh Sharma, Abhimanyu Rai Sharma, and Prabhjot Singh Bajwa. "Design, development and optimization of immediate release tablet of deflazacort." Journal of Drug Delivery and Therapeutics 9, no. 2 (2019): 250–54. http://dx.doi.org/10.22270/jddt.v9i2.2411.

Full text

Abstract:

The objective of the present study was to prepare immediate release tablets (IRTs) of deflazacort by direct compression method. Two types of superdisintegrants i.e. sodium starch glycolate (SSG) and Ac-Di-sol were used in the formulation of tablets. Twelve preliminary batches were prepared by varying the concentration of superdisintegrants. It was found that formulation containing Ac-Di-Sol disintegrated in less time as compared to formulation containing sodium starch glycolate. Values of friability was found to be more in case of formulation containing Ac-Di-Sol. Attempts were also made to pr

APA, Harvard, Vancouver, ISO, and other styles

17

Sharma, Abhimanyu Rai, Birendra Shrivastava, Anurag Bhargava, Shailesh Sharma, Binu Raina, and Prabhjot Singh Bajwa. "Design development and optimization of immediate release tablet of valsartan." Journal of Drug Delivery and Therapeutics 9, no. 2-s (2019): 43–47. http://dx.doi.org/10.22270/jddt.v9i2-s.2444.

Full text

Abstract:

The objective of the present study was to prepare immediate release tablets (IRTs) of valsartan by direct compression method. Two types of superdisintegrants i.e. sodium starch glycolate (SSG) and Ac-Di-sol were used in the formulation of tablets. Twelve preliminary trial batches were prepared by varying the concentration of superdisintegrants. It was found that formulation containing Ac-Di-Sol disintegrated in less time as compared to formulation containing sodium starch glycolate. Values of friability was found to be more in case of formulation containing Ac-Di-Sol. Attempts were also made t

APA, Harvard, Vancouver, ISO, and other styles

18

Parfati, Nani, Karina Citra Rani, and Meilany Meilany. "THE EFFECT OF COPROCESSED SUPERDISINTEGRANTS RATIO (CROSPOVIDONE-SODIUM STARCH GLYCOLATE) TO THE PHYSICOCHEMICAL CHARACTERISTICS OF ATENOLOL ORALLY DISINTEGRATING TABLETS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 2 (2018): 318. http://dx.doi.org/10.22159/ajpcr.2018.v11i2.23010.

Full text

Abstract:

Objective: The objective of this study was to evaluate the effect of coprocessed superdisintegrants (crospovidone-sodium starch glycolate) ratio 1:1; 1:2; and 1:3 to the physicochemical characteristics of atenolol orally disintegrating tablets.Methods: Orally disintegrating tablets of atenolol were prepared by direct compression method. There were three formulas which using three different ratios of coprocessed superdisintegrants (crospovidone-sodium starch glycolate). The ratio of coprocessed superdisintegrants were, 1:1 (formula 1); 1:2 (formula 2); and 1:3 (formula 3). Evaluation of the for

APA, Harvard, Vancouver, ISO, and other styles

19

Kadu, B. M., S. Bhasme, R. D. Bawankar, and D. R. Mundhada. "Formulation and Evaluation of Rapimelt Tablet of Anti-Vertigo Drug (Lorazepam)." International Journal of PharmTech Research 13, no. 4 (2020): 341–49. http://dx.doi.org/10.20902/ijptr.2019.130405.

Full text

Abstract:

A. Rapimelt tablet of Lorazepam was prepared by direct compression method using Indion 414, Cross Carmellose Sodium and sodium starch glycolate as superdisintegrants with aim to get rapid onset of action, improve bioavailability and to give pleasant taste and better mouth feel. The tablets prepared were evaluated for various parameters like various density parameters, thickness, hardness, friability, disintegration time, wetting time and invitro dissolution time and were found to be within limits as per Indian Pharmacopoeia. FT-IR spectra of physical mixture of Lorazepam with Indion 414showedr

APA, Harvard, Vancouver, ISO, and other styles

20

K., Ramanji Reddy* Dr.Chandaka Madhu Dr. Mohammed Omar Sachin Vanji Ahirrao P.Jhansi Lakshmi. "FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF FEXOFENADINE HYDROCHLORIDE." Indo American Journal of Pharmaceutical Sciences 04, no. 09 (2017): 3230–42. https://doi.org/10.5281/zenodo.967492.

Full text

Abstract:

In the present work, mouth dissolving tablets of fexofenadine HCl were designed with a view to enhance patient compliance by direct compression method. The present work studied the effect of superdisintegrants on release rate of fexofenadine HCl in the form of fast disintegrating tablet. For the present study range of superdisintegrants in their different concentrations, were used. The superdisintegrants used were Magnesium stearate, Microcrystalline Cellulose, Cross Povidone, Sodium Starch Glycolate,and Cross Carmellose Sodium. The blends were prepared by direct compression technique. The tab

APA, Harvard, Vancouver, ISO, and other styles

21

Rahman, SM Moshiur, Tushar Saha, Zia Uddin Masum, and Jakir Ahmed Chowdhury. "Evaluation of Physical Properties of Selected Excipients for Direct Compressible Tablet." Bangladesh Pharmaceutical Journal 20, no. 1 (2017): 34–38. http://dx.doi.org/10.3329/bpj.v20i1.32091.

Full text

Abstract:

Excipients play important roles in the manufacturing of direct compressible tablet. The physical properties of excipients like flow properties, bulk density, tapped density, compressibility and diameter of particles are the most important studies which should be taken under consideration. Excipients like lactose, ludipress, avicel, povidone, sodium starch glycolate, sodium lauryl sulfate, sodium carboxy methyl cellulose, polyethylene glycol 4000 (PEG 4000) and maize starch are used and found that PEG 4000, avicel PH-101, ludipress and sodium lauryl sulfate showed an angle of repose below 400 w

APA, Harvard, Vancouver, ISO, and other styles

22

Young, Paul M., Stephen Edge, John N. Staniforth, D. Fraser Steele, and Robert Price. "Interaction of Moisture with Sodium Starch Glycolate." Pharmaceutical Development and Technology 12, no. 2 (2007): 211–16. http://dx.doi.org/10.1080/10837450601168763.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Edge, S., A. M. Belu, U. J. Potter, et al. "Chemical characterisation of sodium starch glycolate particles." International Journal of Pharmaceutics 240, no. 1-2 (2002): 67–78. http://dx.doi.org/10.1016/s0378-5173(02)00109-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Korni, Rama D., Kamala KPV, and V. Sahiti. "Fast Dissolving Tablets of Promethazine Theoclate: Optimization by Box Behnken Design." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 126–31. http://dx.doi.org/10.25258/ijddt.14.1.18.

Full text

Abstract:

HThe current work was planned to optimize promethazine theoclate fast-dissolving tablets using Box Behnken design. The effect of three independent factors, the concentration of camphor (sublimating agent), sodium starch glycolate (superdisintegrant) and β-cyclodextrin (solubility enhancer) on two responses, disintegration time and percent drug release was studied. A total of 27 formulations were prepared and tested for various precompression and postcompression parameters. The correlation between factors and responses was established by plotting contour plots. The independent variables, the co

APA, Harvard, Vancouver, ISO, and other styles

25

Endang Diyah Ikasari. "Optimization Of Sodium Croscarmellose And Sodium Starch Glycolate In Orally Disintegrating Tablets (Odt) Acetosal." Media Farmasi Indonesia 20, no. 1 (2025): 15–23. https://doi.org/10.53359/mfi.v20i1.289.

Full text

Abstract:

Acetosal is a drug that is included in the NSAID class which has anticoagulant properties. Acetosal has low bioavailability due to first-pass effect metabolism, so it is formulated in ODT form to increase the bioavailability of acetosal. This research aims to determine the effect of croscarmellose sodium and sodium starch glycolate concentrations as superdisintegrants on the physical characteristics of acetosal ODT and to determine the concentrations of croscarmellose sodium and sodium starch glycolate as superdisintegrants that produce acetosal ODT with optimum physical characteristics. The r

APA, Harvard, Vancouver, ISO, and other styles

26

Pokhrel, Gopal, Ganga Kunwar, Jun Devi Rai, Sheela Thapa, Sudip Dhakal, and Prashant Basnet. "Formulation and in-vitro Evaluation of Oro-dispersible tablets of Indomethacin." Nepal Journal of Health Sciences 2, no. 1 (2022): 90–97. http://dx.doi.org/10.3126/njhs.v2i1.47172.

Full text

Abstract:

Introduction: Oro-dispersible tablets are rapidly dissolved in saliva without the need for water and are beneficial for renal impaired, bedridden and psychiatric patients. Objective: The study aimed to formulate oro-dispersible tablets of indomethacin with reduced adverse effects, better patient compliance, faster action, and convenience for patients. Methods: Oro-dispersible tablets of indomethacin were prepared using three different super disintegrants; crospovidone, croscarmellose sodium and sodium starch glycolate with three different concentrations (2.5%, 5.2%, and 7.7%) by direct compres

APA, Harvard, Vancouver, ISO, and other styles

27

Shinkar, Dattatraya M., Pooja S. Aher, Parag D. Kothawade, and Avish D. Maru. "FORMULATION AND IN VITRO EVALUATION OF FAST DISSOLVING TABLET OF VERAPAMIL HYDROCHLORIDE." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 10 (2018): 93. http://dx.doi.org/10.22159/ijpps.2018v10i10.28714.

Full text

Abstract:

Objective: The main objective of this research work was to formulate and evaluate fast dissolving tablet of verapamil hydrochloride for the treatment of hypertension.Methods: In this study, fast dissolving tablet were prepared by wet granulation method by using croscarmellose sodium and sodium starch glycolate as superdisintegrants in the concentration of 2%, 4%, and 6%. Polyvinyl pyrollidone K30 is used as a binder. The designed tablets were subjected to various assessment parameters like friability test, hardness test, disintegration test, wetting time, in vitro drug release and drug content

APA, Harvard, Vancouver, ISO, and other styles

28

Nisar, Jan, Mudassir Iqbal, Munawar Iqbal, et al. "Decomposition Kinetics of Levofloxacin: Drug-Excipient Interaction." Zeitschrift für Physikalische Chemie 234, no. 1 (2020): 117–28. http://dx.doi.org/10.1515/zpch-2018-1273.

Full text

Abstract:

AbstractThe present study is focused on the thermal decomposition of Levofloxacin in the absence and presence of different excipients (sodium starch glycolate, magnesium stearate, microcrystalline cellulose and lactose using Thermogravimetry (TG). Fourier Transform Infra Red Spectroscopy (FTIR) and Differential Scanning Calorimetry (DSC) were used to study the possible drug – excipient interaction. It has been shown that the interaction of the first three excipients (sodium starch glycolate, magnesium stearate, and microcrystalline cellulose) with Levofloxacin is physical in nature. Lactose wa

APA, Harvard, Vancouver, ISO, and other styles

29

Rani, Karina Citra, Nani Parfati, and Putu Egik Prasetya. "Pengaruh Komposisi Campuran Fisik Crospovidone-Sodium Starch Glycolate (1:1, 1:2, dan 1:3) terhadap Karakteristik Fisikokimia Sediaan Tablet Orodispersible Atenolol." MPI (Media Pharmaceutica Indonesiana) 1, no. 3 (2017): 127–35. http://dx.doi.org/10.24123/mpi.v1i3.216.

Full text

Abstract:

Penggunaan tablet konvensional atenolol menimbulkan masalah dalam hal kepatuhanminum obat pada pasien geriatri. Hal ini disebabkan terjadinya perubahan fisiologis pada pasiengeriartri seperti susah menelan dan tremor. Pengembangan atenolol dalam bentuk sediaan tabletorodispersible dapat mempercepat waktu hancur tablet di dalam mulut, sehingga awal proses disolusimenjadi lebih cepat. Pemilihan jenis dan komposisi disintegran yang optimal merupakan halpenting dalam formulasi sediaan tablet orodispersible. Kombinasi crospovidone dan sodium starchglycolate sebagai disintegran dalam formulasi sedia

APA, Harvard, Vancouver, ISO, and other styles

30

Patil, R. Y. Patil, and Jitendra V. Shinde. "Design, Development and Characterization of Mouth Dissolving Tablet of Antivirals." PDEAS International Journal of Research in Ayurved and Allied Sciences 3, no. 2 (2019): 03–12. https://doi.org/10.63778/pdeasijraas-arjcpl/2019_10313.

Full text

Abstract:

Abstract: Objective: The main objective of this research work was to design, develop and characterization of mouth dissolving tablet of antivirals. Method: In this study, mouth dissolving tablet was prepared by direct compression method by using natural karaya gum, and synthetic sodium starch glycolate as Superdisintegrants in various concentrations. The designed tablets were subjected to various assessments parameters like hardness test, friability test, in vitro disintegration time, wetting time, in vitro drug release, and drug content. Result: All the ready formulations were subjected to va

APA, Harvard, Vancouver, ISO, and other styles

31

Edge, S., D. F. Steele, J. N. Staniforth, A. Chen, and P. M. Woodcock. "Powder Compaction Properties of Sodium Starch Glycolate Disintegrants." Drug Development and Industrial Pharmacy 28, no. 8 (2002): 989–99. http://dx.doi.org/10.1081/ddc-120006430.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Naji, Ghada Hamid, Worood Hameed Al-Zheery, and Noor Yousif Fareed. "DESIGN AND IN VITRO EVALUATION OF ACRIVASTINE AS ORODISPERSIBLE TABLET USING DIRECT COMPRESSION METHOD." Wiadomości Lekarskie 76, no. 1 (2023): 170–74. http://dx.doi.org/10.36740/wlek202301123.

Full text

Abstract:

The aim: This study aimed to develop mouth-dissolving tablets of Acrivastine, an antihistamine medication, in order to increase its oral bioavailability. Materials and methods: Different super disintegrants, such as crospovidone, croscarmellose sodium, and sodium starch glycolate, were used to make Acrivastine oral dispersible tablets (ODTs). These super disintegrants were utilized in various concentrations. The formulation (F3) with 6% w/w crospovidone had a fast disintegration time (less than 30 seconds) and practically total drug release within 10 minutes. All of the formulations were made

APA, Harvard, Vancouver, ISO, and other styles

33

Y., Shiva Kumar* Dr.T. Mangilal Dr. M. Ravi Kumar J. Naveen. "PREPARATION AND EVALUATION OF TAPENTADOL MOUTH DISSOLVING TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 04 (2019): 8726–36. https://doi.org/10.5281/zenodo.2656643.

Full text

Abstract:

<em>Mouth dissolving tablets are solid dosage forms containing tapentadol as active pharmaceutical ingredient which has analgesic effect, and has superdistegrants like croscarmellose sodium and starch glycolate which disintegrates fast usually less than 60 seconds without the need of water when placed on the tongue. To prepare and evaluate tapentadol mouth dissolving tablet by using direct compression method  and to determine the effect of formulation process and the excipients. Tapentadol MDT were formulated by using ingredients and superdisintegrants like sodium starch glycolate and cro

APA, Harvard, Vancouver, ISO, and other styles

34

Abdelgader, Ahmed Abdalla Bakheit, Daud Baraka Abdallah, Elnazeer I. Hamedelniel, Hiba Atif Mutwakil Gafar, and Mohammed Abdelrahman Mohammed. "Formulation and Optimization of Immediate Release Cajanus Cajan Starch-Based Tablets Containing Metronidazole." Oriental Journal of Physical Sciences 5, no. 1-2 (2020): 16–19. http://dx.doi.org/10.13005/ojps05.01-02.05.

Full text

Abstract:

Starch is found almost in all organs of plants as a carbohydrate reserve. It is considered one of the most commonly used pharmaceutical additives, mainly in tablet dosage forms; it used as a tablet binder when incorporated through the wet granulation process or as a disintegrant. Cajanus cajan has a high level of carbohydrate, which makes it another potential choice as a source for starch. This study aims to investigate and optimize the effect of Cajanus cajan starch concentrations as well as wet massing granulation time on physicochemical properties of metronidazole tablets. The hardness, fri

APA, Harvard, Vancouver, ISO, and other styles

35

Manda, Arthur, Roderick Walker, and Sandile Khamanga. "An Artificial Neural Network Approach to Predict the Effects of Formulation and Process Variables on Prednisone Release from a Multipartite System." Pharmaceutics 11, no. 3 (2019): 109. http://dx.doi.org/10.3390/pharmaceutics11030109.

Full text

Abstract:

The impact of formulation and process variables on the in-vitro release of prednisone from a multiple-unit pellet system was investigated. Box-Behnken Response Surface Methodology (RSM) was used to generate multivariate experiments. The extrusion-spheronization method was used to produce pellets and dissolution studies were performed using United States Pharmacopoeia (USP) Apparatus 2 as described in USP XXIV. Analysis of dissolution test samples was performed using a reversed-phase high-performance liquid chromatography (RP-HPLC) method. Four formulation and process variables viz., microcryst

APA, Harvard, Vancouver, ISO, and other styles

36

Priya, V. A. Vamshi, G. Chandra Sekhara Rao, D. Srinivas Reddy, and V. Prabhakar Reddy. "The Effect of Different Superdisintegrants and their Concentrations on the Dissolution of Topiramate Immediate Release Tablets." International Journal of Pharmaceutical Sciences and Nanotechnology 2, no. 2 (2009): 531–5366. http://dx.doi.org/10.37285/ijpsn.2009.2.2.6.

Full text

Abstract:

The purpose of this study was to investigate the efficiency of superdisintegrants: sodium starch glycolate, croscarmellose sodium and crospovidone in promoting tablet disintegration and drug dissolution of Topiramate immediate release tablets. The efficiency of superdisintegrants was tested, by considering four concentrations, viz., like 2%, 3%, 4% and 5% in the formulations. The dissolution was carried out in USP apparatus II at 50 rpm with distilled water as a dissolution medium. The dissolution rate of the model drug topiramate was found highly dependent on the tablet disintegration, on the

APA, Harvard, Vancouver, ISO, and other styles

37

Sharma, Mahavir K., Rupa Singh, Tejas K. Patel, Bhavik Jani, and Dhairyashri Kher. "Formulation and Evaluation of Mouth Dissolving Tablet of Biperiden HCL for Treatments of Parkinson’s Disease." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, no. 04 (2023): 1533–37. http://dx.doi.org/10.25258/ijddt.13.4.63.

Full text

Abstract:

Seven formulations were developed using superdisintegrating substances like sodium starch glycolate, crospovidone, and cross-carmellose sodium at different concentrations. Three batches were created by employing varying concentrations of the super disintegration approach, utilizing sodium starch glycolate as the superdisintegrating agent. The batches underwent evaluation regarding sensory characteristics, firmness, breakability, weight consistency, disintegration time in a simulated environment, time is taken for wetting, laboratory tests on drug release within a controlled environment, and as

APA, Harvard, Vancouver, ISO, and other styles

38

Putri, Arine Astika, Desy Nawangsari, and Khamdiyah Indah Kurniasih. "FORMULASI SEDIAAN ORALLY DISINTEGRATING TABLET (ODT) ASPIRIN DENGAN SODIUM STARCH GLYCOLATE SEBAGAI SUPERDISINTEGRANT." Pena Medika : Jurnal Kesehatan 14, no. 1 (2024): 407–17. https://doi.org/10.31941/pmjk.v14i1.3713.

Full text

Abstract:

Aspirin adalah NSAID salisilat yang digunakan sebagaiagen antiplatelet dalam pengobatan stroke. Kematianakibat stroke dalam waktu 5 tahun, lebih dari separuhpasien stroke berusia dangt; Seorang berusia 45 tahunyang meninggal. Banyak pasien lanjut usia yang tidak maumenerima/mengonsumsi tablet karena takut tersedak ataukesulitan menelan. Tablet yang hancur secara oral (ODT) adalah sediaan yang lebih cepat hancur, hancur dalamwaktu kurang dari 60 detik bila dimasukkan ke dalammulut, dan tidak memerlukan tambahan air untuk ditelan. Tujuan penelitian ini adalah untuk mengetahui pengaruhkonsentrasi

APA, Harvard, Vancouver, ISO, and other styles

39

ÇOMOĞLU, Tansel. "FARKLI SÜPER DAĞITICILARIN KETOPROFEN İÇEREN AĞIZDA DAĞILAN TABLETLERİN İN VİTRO KARAKTERİZASYON PARAMETRELERİ ÜZERİNDEKİ ETKİSİNİN DEĞERLENDİRİLMESİ." Ankara Universitesi Eczacilik Fakultesi Dergisi 48, no. 2 (2024): 10. http://dx.doi.org/10.33483/jfpau.1425266.

Full text

Abstract:

Objective: Orally Disintegrating Tablets (ODTs) have revolutionized pharmaceutical drug delivery, offering a patient-friendly alternative for those struggling with conventional tablet swallowing. This study delves into the impact of superdisintegrants (crospovidone, sodium starch glycolate, and croscarmellose sodium) on the in vitro characterization of Ketoprofen-containing ODTs. ODTs are designed to rapidly disintegrate in the oral cavity without water, enhancing patient compliance, ensuring faster therapeutic onset, and providing convenience. Material and Method: The micromeritic properties

APA, Harvard, Vancouver, ISO, and other styles

40

Mane, Swapna, Ritesh Bathe, and Sandhyarani Awatade. "Formulation and Evaluation of Fast Disintegrating Tablets of Atenolol Using Natural and Synthetic Superdisintegrants." Journal of Drug Delivery and Therapeutics 9, no. 2-s (2019): 150–58. http://dx.doi.org/10.22270/jddt.v9i2-s.2476.

Full text

Abstract:

Oral disintegrating tablet (ODT) is defined as “A solid dosage form containing medical substances or active ingredient which disintegrates rapidly usually within a matter of seconds when placed upon the tongue”. The aim of the present research is to formulate Atenolol fast disintegrating tablets. Atenolol is β1- cardio selective adrenergic receptor blocker, widely used in the treatment of hypertension, angina pectoris, arrhythmias and myocardial infarction. It works by slowing down the heart and reducing the work load of the heart. The conventional tablets of atenolol are reported to exhibit f

APA, Harvard, Vancouver, ISO, and other styles

41

Rao, N. G. Raghavendra, Tarun Patel, and Rathan Kumar. "Development of Fast Dissolving Carbamazepine Tablets: Effect of Functionality of Superdisintegrants." International Journal of Pharmaceutical Sciences and Nanotechnology 3, no. 1 (2010): 824–33. http://dx.doi.org/10.37285/ijpsn.2010.3.1.5.

Full text

Abstract:

Carbamazepine, a dibenzapine derivative with structure resembling that of tricyclic antidepressants, is used in the treatment of epilepsy. The major problem of this drug is very low solubility in biological fluids and poor bioavailability after oral administration. Carbamazepine fast dissolving tablets (FDT) have been prepared by direct compression method. Effects of superdisintegrants (such as croscarmellose sodium, crospovidone and sodium starch glycolate) on wetting time, disintegrating time, drug content, in vitro release, and stability parameters have been studied. The prepared tablets we

APA, Harvard, Vancouver, ISO, and other styles

42

Mandal, Kalidas, and Rakesh Kumar Jat. "Formulation, Development and Evaluation of Perampanel Oral Dispersible Tablets Utilizing Screening of Additives." Journal of Drug Delivery and Therapeutics 14, no. 12 (2024): 108–16. https://doi.org/10.22270/jddt.v14i12.6871.

Full text

Abstract:

The mouth dissolving tablets are prepared and formulated utilizing different additives like plasticizers, polymers and other bulk forming agents. There are many different batches are manufactured and tested for their evaluation parameters like disintegration test, dissolution test, content uniformity test and weight variation tests. The many bateches are tested and one of the optimized batch is selected for pharmacological action and marketing purpose. The analytical method was developed as according to calibration curve. Oral dispersible tablets of perampenal have been prepared and formulated

APA, Harvard, Vancouver, ISO, and other styles

43

R, Natarajan, N. Patel, Rajendran N N, and M. Rangapriya. "Formulation and Evaluation of Immediate Release Bilayer Tablets of Telmisartan and Hydrochlorothiazide." International Journal of Pharmaceutical Sciences and Nanotechnology 4, no. 3 (2011): 1477–83. http://dx.doi.org/10.37285/ijpsn.2011.4.3.6.

Full text

Abstract:

The main goal of this study was to develop a stable formulation of antihypertensive drugs telmisartan and hydrochlorothiazide as an immediate-release bilayer tablet and to evaluate the dissolution profile in comparison with a reference product. The formulation development work was initiated with wet granulation. Telmisartan was converted to its sodium salt by dissolving in aqueous solution of sodium hydroxide to improve solubility and drug release. Lactose monohydrate and microcrystalline cellulose were used as diluents. Starch paste is prepared in purified water and was used as the binder. So

APA, Harvard, Vancouver, ISO, and other styles

44

Nzekwe, M. U., A. K. Olowosulu, Y. E. Apeji, and T. O. Olurishe. "EVALUATION OF THE EFFECT OF VARIOUS SUPERDISINTEGRANTS ON THE DRUG RELEASE PROFILE OF OMEPRAZOLE CORE TABLETS." Archives of Pharmaceutical Sciences and Biotechnology Journal 4, no. 2 (2025): 48–57. https://doi.org/10.47514/apsbj.2024.4.2.005.

Full text

Abstract:

Background: Superdisintegrants play a crucial role in enhancing tablet disintegration and, consequently, drug release. Omeprazole, a proton pump inhibitor used in treating gastroesophageal reflux disease (GERD), will benefit from rapid disintegration and dissolution to ensure prompt therapeutic action. Aim: The study investigated the influence of three distinct superdisintegrants—croscarmellose sodium, sodium starch glycolate, and crospovidone—on the physical and functional properties of omeprazole core tablets. Methods: Tablets were formulated with varying concentrations of each superdisinteg

APA, Harvard, Vancouver, ISO, and other styles

45

Puri, Abhijeet Vishnu, Prakash D. Khandagale, Ankita U. Tiwari, Rekhadevi H. Chaudhary, and Sonam B. Kartan. "Synthesis and Physicochemical Characterization of Banana Starch Tartrate and its Application as Disintegrant in Telmisartan Tablets." Journal of Drug Delivery and Therapeutics 10, no. 3 (2020): 65–72. http://dx.doi.org/10.22270/jddt.v10i3.4089.

Full text

Abstract:

The present investigation was aimed to isolate banana starch (BS), synthesis of banana starch tartrate (BST), characterization, and application as a novel disintegrant in telmisartan tablets. Starch tartrate was synthesized by the esterification process by the treatment of tartaric acid on the backbone of the BS. Synthesized BST was found to be fine, slightly free-flowing and crystalline powder. The synthesized BST was subjected to Scanning Electron Microscopy (SEM) and micrometric evaluation. Flow properties of BS and BST were determined as an angle of repose, bulk density, tapped density, Ca

APA, Harvard, Vancouver, ISO, and other styles

46

Jain, P., A. Mishra, and A. Pathak. "PREPARATION & EVALUATION OF ORODISPERSIBLE TABLET CONTAINING ASPIRIN BY SUBLIMATION METHOD." INDIAN DRUGS 52, no. 12 (2015): 60–62. http://dx.doi.org/10.53879/id.52.12.10465.

Full text

Abstract:

Orodispersible tablets are uncoated tablets which when taken into the mouth, get easily dispersed within 3 min before swallowing. they are also known as orally disintegrating tablets, mouth-dissolving tablets, rapid dissolving tablets fast-disintegrating tablets, fast-dissolving tablets. In this work, sublimation process was used to prepare orodispersible tablets of aspirin by formulating various batches using different concentration of sodium starch glycolate, camphor and cross povidone. An effort was made by using two modes, first, to increase water uptake for the fast dispersion by creating

APA, Harvard, Vancouver, ISO, and other styles

47

Aneela Manzoor. "Review article: sodium starch glycolate as a super disintegrant." Journal of Contemporary Pharmacy 5, no. 1 (2021): 33–39. http://dx.doi.org/10.56770/jcp2021515.

Full text

Abstract:

Sodium starch glycolate (SSG) is most widely used excipient in the field of pharmaceutical sciences. SSG is extensively used as a superdisintegrant in different drug formulations. This review article aims to discuss chemistry, synthesis, level used as superdisintegrant, different types of SSG’s and various physicochemical properties. SSG available as different brands i.e Primojel, Explotab and Vivastar with different properties. Excipient, generally considered as an inert component, are of great importance in drug product development. Interchange between different suppliers can lead to final p

APA, Harvard, Vancouver, ISO, and other styles

48

Young, Paul, Stephen Edge, John Staniforth, D. Fraser Steele, and Robert Price. "Dynamic Vapor Sorption Properties of Sodium Starch Glycolate Disintegrants." Pharmaceutical Development and Technology 10, no. 2 (2005): 249–59. http://dx.doi.org/10.1081/pdt-200054448.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Young, Paul M., Stephen Edge, John N. Staniforth, D. Fraser Steele, and Robert Price. "Dynamic Vapor Sorption Properties of Sodium Starch Glycolate Disintegrants." Pharmaceutical Development and Technology 10, no. 2 (2005): 249–59. http://dx.doi.org/10.1081/pdt-54448.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Putra, Okta Nama, Ida Musfiroh, Derina Paramitasari, et al. "Sago-Starch-Derived Sodium Starch Glycolate: An Effective Superdisintegrant to Enhance Formulation Performance." Polymers 17, no. 9 (2025): 1208. https://doi.org/10.3390/polym17091208.

Full text

Abstract:

This study focused on optimizing sago-starch-derived sodium starch glycolate (SSG) as a superdisintegrant using a Response Surface Methodology (RSM). The aim was to enhance the formulation performance by achieving an optimal degree of substitution (DS) in the synthesis of SSG from sago starch and evaluating its performance in mefenamic acid tablet formulation. The SSG was synthesized using an organic solvent slurry method, which involves crosslinking starch with sodium trimetaphosphate (STMP) and substituting it with sodium monochloroacetate (SMCA). The reaction conditions, including the tempe

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!