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1

&NA;. "Therapeutic applications." Inpharma Weekly &NA;, no. 734 (1990): 18–19. http://dx.doi.org/10.2165/00128413-199007340-00043.

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2

Weissberg, Dov, and Yael Refaely. "Pleuroscopy: Therapeutic Applications." Scandinavian Journal of Thoracic and Cardiovascular Surgery 30, no. 1 (1996): 1–10. http://dx.doi.org/10.3109/14017439609107234.

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3

Ivey, Gavin. "Bion's therapeutic applications." Psychoanalytic Psychotherapy 25, no. 1 (2011): 92–104. http://dx.doi.org/10.1080/02668734.2010.538073.

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4

&NA;. "??? and therapeutic applications." Inpharma Weekly &NA;, no. 769 (1991): 19–20. http://dx.doi.org/10.2165/00128413-199107690-00053.

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&NA;. "Streptokinase: therapeutic applications." Inpharma Weekly &NA;, no. 729 (1990): 22–23. http://dx.doi.org/10.2165/00128413-199007290-00051.

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6

Fritzsche, Peggy. "Antegrade Pyelography: Therapeutic Applications." Radiologic Clinics of North America 24, no. 4 (1986): 573–86. http://dx.doi.org/10.1016/s0033-8389(22)02325-9.

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7

Volpi, Nicola. "Therapeutic Applications of Glycosaminoglycans." Current Medicinal Chemistry 13, no. 15 (2006): 1799–810. http://dx.doi.org/10.2174/092986706777452470.

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8

Mobaraki, Mohammadmahdi, Sonali Karnik, Yue Li, and David K. Mills. "Therapeutic Applications of Halloysite." Applied Sciences 12, no. 1 (2021): 87. http://dx.doi.org/10.3390/app12010087.

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In recent years, nanomaterials have attracted significant research interest for applications in biomedicine. Many kinds of engineered nanomaterials, such as lipid nanoparticles, polymeric nanoparticles, porous nanomaterials, silica, and clay nanoparticles, have been investigated for use in drug delivery systems, regenerative medicine, and scaffolds for tissue engineering. Some of the most attractive nanoparticles for biomedical applications are nanoclays. According to their mineralogical composition, approximately 30 different nanoclays exist, and the more commonly used clays are bentonite, ha
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9

Crooke, Stanley T. "Therapeutic Applications of Oligonucleotides." Nature Biotechnology 10, no. 8 (1992): 882–86. http://dx.doi.org/10.1038/nbt0892-882.

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10

Crooke, S. T. "Therapeutic Applications of Oligonucleotides." Annual Review of Pharmacology and Toxicology 32, no. 1 (1992): 329–76. http://dx.doi.org/10.1146/annurev.pa.32.040192.001553.

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11

Kostoglou-Athanassiou, Ifigenia. "Therapeutic applications of melatonin." Therapeutic Advances in Endocrinology and Metabolism 4, no. 1 (2013): 13–24. http://dx.doi.org/10.1177/2042018813476084.

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Melatonin is a methoxyindole synthesized within the pineal gland. The hormone is secreted during the night and appears to play multiple roles within the human organism. The hormone contributes to the regulation of biological rhythms, may induce sleep, has strong antioxidant action and appears to contribute to the protection of the organism from carcinogenesis and neurodegenerative disorders. At a therapeutic level as well as in prevention, melatonin is used for the management of sleep disorders and jet lag, for the resynchronization of circadian rhythms in situations such as blindness and shif
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12

Gaffney, John, Sabine Matou-Nasri, Marta Grau-Olivares, and Mark Slevin. "Therapeutic applications of hyaluronan." Mol. BioSyst. 6, no. 3 (2010): 437–43. http://dx.doi.org/10.1039/b910552m.

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13

Unger, Evan C., Terry O. Matsunaga, Thomas P. McCreery, et al. "Therapeutic applications of microbubbles." Journal of the Acoustical Society of America 110, no. 5 (2001): 2669. http://dx.doi.org/10.1121/1.4777115.

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14

Kaur, Gurjot, and Ipsita Roy. "Therapeutic applications of aptamers." Expert Opinion on Investigational Drugs 17, no. 1 (2007): 43–60. http://dx.doi.org/10.1517/13543784.17.1.43.

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15

Yap, P. L., and H. A. Leaver. "Therapeutic applications of phagocytes." FEMS Microbiology Letters 47, no. 5 (1989): 313–14. http://dx.doi.org/10.1111/j.1574-6968.1989.tb02405.x.

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16

Ferraro, Angelo. "Biomaterials and therapeutic applications." IOP Conference Series: Materials Science and Engineering 108 (March 18, 2016): 012021. http://dx.doi.org/10.1088/1757-899x/108/1/012021.

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17

PINEDA, ALVARO A. "Applications of Therapeutic Apheresis." Mayo Clinic Proceedings 69, no. 9 (1994): 893–94. http://dx.doi.org/10.1016/s0025-6196(12)61796-0.

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18

Unger, Evan C., Terry Onichi Matsunaga, Thomas McCreery, Patricia Schumann, Robert Sweitzer, and Rachel Quigley. "Therapeutic applications of microbubbles." European Journal of Radiology 42, no. 2 (2002): 160–68. http://dx.doi.org/10.1016/s0720-048x(01)00455-7.

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19

Rook, Alain H., Julia H. Cohen, Stuart R. Lessin, and Benjamin R. Vowels. "Therapeutic Applications of Photopheresis." Dermatologic Clinics 11, no. 2 (1993): 339–47. http://dx.doi.org/10.1016/s0733-8635(18)30272-9.

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20

Winum, Jean-Yves, Andrea Scozzafava, Jean-Louis Montero, and Claudiu T. Supuran. "Therapeutic applications of sulfamates." Expert Opinion on Therapeutic Patents 14, no. 9 (2004): 1273–308. http://dx.doi.org/10.1517/13543776.14.9.1273.

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21

Zhao, Yunfeng, Michael Russ, Charles Morgan, Sybille Muller, and Heinz Kohler. "Therapeutic applications of superantibodies." Drug Discovery Today 10, no. 18 (2005): 1231–36. http://dx.doi.org/10.1016/s1359-6446(05)03530-0.

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22

TERHAAR, G. "Therapeutic applications of ultrasound." Progress in Biophysics and Molecular Biology 93, no. 1-3 (2007): 111–29. http://dx.doi.org/10.1016/j.pbiomolbio.2006.07.005.

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23

Maurya, Nancy, and Bharath Kumar Velmurugan. "Therapeutic applications of cannabinoids." Chemico-Biological Interactions 293 (September 2018): 77–88. http://dx.doi.org/10.1016/j.cbi.2018.07.018.

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24

Verhoeven, Seimbille, and Dalm. "Therapeutic Applications of Pretargeting." Pharmaceutics 11, no. 9 (2019): 434. http://dx.doi.org/10.3390/pharmaceutics11090434.

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Targeted therapies, such as radioimmunotherapy (RIT), present a promising treatment option for the eradication of tumor lesions. RIT has shown promising results especially for hematologic malignancies, but the therapeutic efficacy is limited by unfavorable tumor-to-background ratios resulting in high radiotoxicity. Pretargeting strategies can play an important role in addressing the high toxicity profile of RIT. Key to pretargeting is the concept of decoupling the targeting vehicle from the cytotoxic agent and administrating them separately. Studies have shown that this approach has the abilit
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25

Danel, C., D. Israel-Biet, U. Costabel, LM Fabbri, and H. Klech. "Therapeutic applications of BAL." European Respiratory Journal 3, no. 8 (1990): 960–61. http://dx.doi.org/10.1183/09031936.93.03080960.

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26

Kijima, H. "Therapeutic applications of ribozymes." Pharmacology & Therapeutics 68, no. 2 (1995): 247–67. http://dx.doi.org/10.1016/0163-7258(95)02008-x.

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27

Shaker, M. "Therapeutic applications of prostaglandins." Prostaglandins 47, no. 2 (1994): 79. http://dx.doi.org/10.1016/0090-6980(94)90078-7.

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28

Santarpia, George, and Eric Carnes. "Therapeutic Applications of Aptamers." International Journal of Molecular Sciences 25, no. 12 (2024): 6742. http://dx.doi.org/10.3390/ijms25126742.

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Affinity reagents, or target-binding molecules, are quite versatile and are major workhorses in molecular biology and medicine. Antibodies are the most famous and frequently used type and they have been used for a wide range of applications, including laboratory techniques, diagnostics, and therapeutics. However, antibodies are not the only available affinity reagents and they do have significant drawbacks, including laborious and costly production. Aptamers are one potential alternative that have a variety of unique advantages. They are single stranded DNA or RNA molecules that can be selecte
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29

Collier, Joe. "Therapeutic Applications of Prostaglandins." Journal of the Royal College of Physicians of London 28, no. 3 (1994): 272–73. https://doi.org/10.1016/s0035-8819(25)00823-2.

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30

Devilal Pardhe, Deepak. "The Therapeutic Applications of Cassia fistula Linn.: A Review." International Journal of Science and Research (IJSR) 13, no. 1 (2024): 687–89. http://dx.doi.org/10.21275/sr24109130755.

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31

Karges, Johannes, Ryjul W. Stokes, and Seth M. Cohen. "Metal complexes for therapeutic applications." Trends in Chemistry 3, no. 7 (2021): 523–34. http://dx.doi.org/10.1016/j.trechm.2021.03.006.

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32

Hoogendoorn, Ayla, Thomas D. Avery, Jiahe Li, Christina Bursill, Andrew Abell, and Peter M. Grace. "Emerging Therapeutic Applications for Fumarates." Trends in Pharmacological Sciences 42, no. 4 (2021): 239–54. http://dx.doi.org/10.1016/j.tips.2021.01.004.

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33

Prajapati, DS, JB Dave, JS Shah, and CN Patel. "Therapeutic applications of monoclonal antibodies." Systematic Reviews in Pharmacy 2, no. 1 (2011): 37. http://dx.doi.org/10.4103/0975-8453.83437.

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34

Winkler, Johannes. "Oligonucleotide conjugates for therapeutic applications." Therapeutic Delivery 4, no. 7 (2013): 791–809. http://dx.doi.org/10.4155/tde.13.47.

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35

Graßmann, Carsten, Evelyn Lempa, Maike Rabe, Andreas Kitzig, Edwin Naroska, and Benno Neukirch. "Electroluminescent Textile for Therapeutic Applications." Advances in Science and Technology 100 (October 2016): 73–78. http://dx.doi.org/10.4028/www.scientific.net/ast.100.73.

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Alternating-current (AC) electroluminescent (EL) devices on fabrics with high brightness are presented. The EL-devices were fabricated via knife coating; inorganic luminous pigments are based on zinc sulfide. Effects of parameters influencing the brightness were investigated. These parameters are the AC-voltage, AC-frequency, AC-waveform, layer composition of the luminous capacitor and the fabric. Introducing a flexible reflecting dielectric layer enhances the light yield on fine woven fabrics with green luminous pigment. This can be achieved with small concentrations of reflective white pigme
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36

Tsenteradze, S. L., and M. G. Poluektov. "Therapeutic aspects of melatonin applications." Meditsinskiy sovet = Medical Council, no. 10 (August 12, 2021): 80–84. http://dx.doi.org/10.21518/2079-701x-2021-10-80-84.

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The results of multicenter clinical trials show the broad potential of melatonin since discovery of this adaptogen to the present day. Melatonin is a neuropeptide that is synthesized mainly in the small brain gland, the pineal gland, and has a unique effect in humans and animals. Using melatonin, the pineal gland participates in the organization of circadian periodism and regulation of cyclic processes, acting as an intermediary between the pacemaker mechanism of the suprachiasmatic nuclei (SCN) and peripheral organs. The pineal gland and the SCN of the hypothalamus form part of the system of
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37

Ulger, Oner, and Gokhan Burcin Kubat. "Therapeutic applications of mitochondrial transplantation." Biochimie 195 (April 2022): 1–15. http://dx.doi.org/10.1016/j.biochi.2022.01.002.

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38

Nemeth, Elizabeta. "Hepcidin biology and therapeutic applications." Expert Review of Hematology 3, no. 2 (2010): 153–55. http://dx.doi.org/10.1586/ehm.10.1.

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39

Chhaiya, Sunita, Dimple Mehta, and Bhaven Kataria. "Ivermectin: pharmacology and therapeutic applications." International Journal of Basic & Clinical Pharmacology 1, no. 3 (2012): 132. http://dx.doi.org/10.5455/2319-2003.ijbcp002712.

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40

Foley, Kevin F., Kevin P. DeSanty, and Richard E. Kast. "Bupropion: pharmacology and therapeutic applications." Expert Review of Neurotherapeutics 6, no. 9 (2006): 1249–65. http://dx.doi.org/10.1586/14737175.6.9.1249.

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41

Oh, Ki Young, and Kyung hee Kim. "Clinical applications of therapeutic phlebotomy." Journal of Blood Medicine Volume 7 (July 2016): 139–44. http://dx.doi.org/10.2147/jbm.s108479.

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42

Hasty, Jeff. "Engineered Microbes for Therapeutic Applications." ACS Synthetic Biology 1, no. 10 (2012): 438–39. http://dx.doi.org/10.1021/sb300105b.

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43

Latronico, Michael V. G., and Gianluigi Condorelli. "Therapeutic applications of noncoding RNAs." Current Opinion in Cardiology 30, no. 3 (2015): 213–21. http://dx.doi.org/10.1097/hco.0000000000000162.

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44

Yale, Harry L. "THERAPEUTIC APPLICATIONS OF ORGANOMETALLIC COMPOUNDS." Annals of the New York Academy of Sciences 125, no. 1 (2006): 189–97. http://dx.doi.org/10.1111/j.1749-6632.1965.tb45390.x.

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45

Liu, Xiaoli, Yuan Gao, Rona Chandrawati, and Leticia Hosta-Rigau. "Therapeutic applications of multifunctional nanozymes." Nanoscale 11, no. 44 (2019): 21046–60. http://dx.doi.org/10.1039/c9nr06596b.

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46

Ösapay, George, and Klara Ösapay. "Therapeutic applications of somatostatin analogues." Expert Opinion on Therapeutic Patents 8, no. 7 (1998): 855–70. http://dx.doi.org/10.1517/13543776.8.7.855.

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47

Yip, Theresa, Xiaodong Qi, Hao Yan, and Yung Chang. "Therapeutic applications of RNA nanostructures." RSC Advances 14, no. 39 (2024): 28807–21. http://dx.doi.org/10.1039/d4ra03823a.

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Non-immunogenic RNA nanostructures are functionalized for/with RNAi, mRNA, ribozymes, CRISPR, and small molecule drugs. Immunogenic RNA nanostructures are designed as immunostimulants and cancer vaccine platforms. Created in Biorender.com.
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48

Knauert, Melissa, Sandeep Vangala, Maria Haslip, and Patty J. Lee. "Therapeutic Applications of Carbon Monoxide." Oxidative Medicine and Cellular Longevity 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/360815.

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Heme oxygenase-1 (HO-1) is a regulated enzyme induced in multiple stress states. Carbon monoxide (CO) is a product of HO catalysis of heme. In many circumstances, CO appears to functionally replace HO-1, and CO is known to have endogenous anti-inflammatory, anti-apoptotic, and antiproliferative effects. CO is well studied in anoxia-reoxygenation and ischemia-reperfusion models and has advanced to phase II trials for treatment of several clinical entities. In alternative injury models, laboratories have used sepsis, acute lung injury, and systemic inflammatory challenges to assess the ability o
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49

McFarland, Dennis J., Janis Daly, Chadwick Boulay, and Muhammad A. Parvaz. "Therapeutic applications of BCI technologies." Brain-Computer Interfaces 4, no. 1-2 (2017): 37–52. http://dx.doi.org/10.1080/2326263x.2017.1307625.

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50

Hong, Elizabeth M., Carin K. Ingemarsdotter, and Andrew M. L. Lever. "Therapeutic applications of trans-splicing." British Medical Bulletin 136, no. 1 (2020): 4–20. http://dx.doi.org/10.1093/bmb/ldaa028.

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Abstract Background RNA trans-splicing joins exons from different pre-mRNA transcripts to generate a chimeric product. Trans-splicing can also occur at the protein level, with split inteins mediating the ligation of separate gene products to generate a mature protein. Sources of data Comprehensive literature search of published research papers and reviews using Pubmed. Areas of agreement Trans-splicing techniques have been used to target a wide range of diseases in both in vitro and in vivo models, resulting in RNA, protein and functional correction. Areas of controversy Off-target effects can
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