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Dissertations / Theses on the topic 'And Therapeutic Properties'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Brand, Anneke Mari. "Therapeutic properties of the lantibiotic nisin F." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/79873.

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Thesis (PhD)-- Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: Bacterial resistance against antibiotic treatments is a global concern and resistance to almost every known antibiotic has already been reported. There is thus a significant need for the development of novel antimicrobial drugs. In addition to probiotic traits, certain bacteria have the ability to produce antimicrobial peptides, referred to as bacteriocins. Lantibiotics, a group of small ribosomally synthesized bacteriocins, recently gained interest for their application in the medical field. Lantibiotics have a very specific

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2

Alder, Louise B. A. "Immunoregulatory properties of polyclonal immunoglobulin for therapeutic use." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361937.

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Niculescu, O., C. Gaidau, D. Simion, M. D. Berechet, and D. Gurau. "Articles made of sheep fur with therapeutic properties." Thesis, Київський національний університет технологій та дизайну, 2020. https://er.knutd.edu.ua/handle/123456789/15559.

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4

Kilinkissa, Ornella Edlyne Youdaga. "Physical chemical properties of selected pharmaceutical co-crystals." Thesis, Cape Peninsula University of Technology, 2014. http://hdl.handle.net/20.500.11838/731.

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Thesis submitted in fulfilment of the requirements for the degree Magister Technologiae: Chemistry in the Faculty of Applied Sciences at the CAPE PENINSULA UNIVERSITY OF TECHNOLOGY 2014<br>The solid state modification of a given active pharmaceutical ingredient is a desired way to alter its physicochemical properties, such as solubility or bioavailability. The solubilitymelting point relationship of the ensuing co-crystal or salt is not fully understood. In this thesis, a series of model co-crystals and pharmaceutical co-crystals and salts of baclofen were investigated. The model co-crystals w

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Ghorani, Behrouz. "Production and properties of electrospun webs for therapeutic applications." Thesis, University of Leeds, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590271.

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The electro spinning and properties of fibrous webs containing drugs, biomolecules and other potentially therapeutic compounds was studied. Two different technologies were investigated. The first dealt with incorporation and release of compounds including drugs using insoluble electrospun fibres comprised of cellulose acetate. A systematic parameter study was completed for producing electro spun cellulose acetate fibres that were substantially free of bead defects and the effect of different solvent systems and process parameters during electrospinning cellulose acetate were evaluated in respe

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6

Fernandes, Ana Isabel Henriques Dias. "Polysialylation of proteins : an approach to improve their therapeutic properties." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265405.

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7

Zhang, Jingjing, and 张晶晶. "The anti-cancer properties of cyclometalated gold(III) complexes and organogold(III) supramolecular polymers." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208171.

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Prompted by the successful clinical application of cisplatin in cancer therapy, worldwide efforts have been devoted to develop new metal-based drugs for anticancer treatment. Gold(III) complexes at first received attention as anti-cancer drug candidates because of their square-planar geometry which resembles that of platinum(II) complexes. Subsequent studies revealed that various gold(III) complexes displayed promising anti-cancer activities with different biological mechanisms. Although some achievements have been obtained in the development of anti-cancer gold(III) complexes, challenges incl

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8

Daniel, Sheril. "An investigation into the neuroprotective properties of curcumin." Thesis, Rhodes University, 2003. http://hdl.handle.net/10962/d1003231.

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An increasing number of studies show that nutritional antioxidants such as vitamin E and polyphenols are capable of blocking neuronal death in vitro and may have therapeutic properties in animal models of neurodegenerative diseases including Alzheimer’s and Parkinson’s diseases. In the present study, the neuroprotective ability of one such polyphenolic antioxidant, curcumin, was investigated. Curcumin is the yellow curry spice derived from turmeric, and is widely used as a dietary component and herbal medicine in India. Most neurological disorders are postulated to have an oxidative or excitot

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9

Marnewick, Jeanine Lucasta. "Cancer modulating properties of unique South African herbal teas (rooibos and honeybush) in short term in vitro and in vivo carcinogenesis assays." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/21888.

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Dissertation (PhD)--University of Stellenbosch, 2004.<br>ENGLISH ABSTRACT: This thesis provides the first scientific evidence on the cancer modulating properties of two unique South African herbal teas, rooibos (Aspalathus Iinearis) and honeybush (Cyclopia intermedia) utilizing in vitro as well as in vivo carcinogenesis assays by: • Demonstrating the in vitro antimutagenic activity of aqueous extracts of the herbal teas against the metabolic activated mutagens, 2-acetylaminofluorene (2- AAF) and the mycotoxin, aflatoxin B1 (AFB,) as well as, to a certain extent, against the direct acting

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10

Lara, Corona Maribel. "Study of the properties of exosomes modified as therapeutic vehicles in vivo." Electronic Thesis or Diss., Université Paris Cité, 2024. http://www.theses.fr/2024UNIP5217.

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Les vésicules extracellulaires (VE) sont des structures lipidiques sécrétées par tous les types de cellules étudiés jusqu'à présent. Une fois libérées, elles peuvent traverser différentes barrières biologiques pour cibler les cellules réceptrices localement et systémiquement. Leur composition et leur contenu indiquent l'état physiologique de la cellule productrice et, par conséquent, elles ont suscité une grande attention pour leur utilisation dans des applications cliniques en tant que biomarqueurs non invasifs. Par ailleurs, la capacité des VE à cibler et à délivrer du matériel aux cellules

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11

Zhang, Jing, and 张婧. "The immunomodulatory properties of Cordyceps cicadae on resting and proliferating human T-lymphocytes." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49618039.

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Cordyceps cicadae, a parasitic fungus, has been used as a traditional Chinese herb for treatment of illnesses related to immune dysfunction. However, mechanistic actions are not entirely clear. The specific aim of the present study is to investigate the immunological mechanisms of C. cicadae on human T lymphocytes in vitro. The two main objectives carried out in the present study in order to achieve the aim are: i. to investigate the immunological effects of the water extract of C.cicadae on human resting and proliferating T lymphocytes; 2. to investigate the adjuvant property of C.cicadae wi

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Wang, Xiao Suo School of Medical Science UNSW. "Mass spectrometric characterization and analysis of anti-oxidative properties of medicinal herbs." Awarded by:University of New South Wales. School of Medical Science, 2003. http://handle.unsw.edu.au/1959.4/19180.

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The aim of this project was to investigate a range of medicinal herbs which have radical scavenging and antioxidant activities and then apply novel mass spectrometric techniques to investigate and analyse active components responsible for their pharmaceutical actions. A sensitive electron capture negative ionization of gas chromatography-mass spectrometry (ECNI-GC-MS) method was developed to assess hydroxyl radical production, as indicated by 3.4-dihydroxyphenylacetic acid (DOPAC) production, which allows excellent evaluation of hydroxyl radical scavenging and antioxidant activity of a number

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13

Dairam, Amichand. "An investigation into the neuroprotective properties of the non-steroidal anti-inflammatory agents tolmetin, sulindac and turmeric." Thesis, Rhodes University, 2006. http://hdl.handle.net/10962/d1003230.

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Accumulating evidence suggests that anti-inflammatory agents and antioxidants have neuroprotective properties and may be beneficial in the treatment of neurodegenerative disorders. In the present study, the possible neuroprotective properties of tolmetin, sulindac and turmeric were investigated. The antioxidant effects of tolmetin and sulindac were determined by inducing free radical generation with quinolinic acid (QA), cyanide or iron (II) in rat brain homogenates or primary hippocampal neurons. Tolmetin and sulindac significantly reduce lipid peroxidation and scavenge the superoxide anion.

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14

Du, Bin. "Effect of molecular weight and structure on anti-inflammatory properties of polysaccharide from submerged mycelial fermentation of schizophyllum commune /Du Bin." HKBU Institutional Repository, 2016. https://repository.hkbu.edu.hk/etd_oa/363.

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Medicinal mushrooms are therapeutic agents in traditional folk medicines. Previous studies have shown that a number of biologically active compounds in medicinal mushrooms contributed therapeutic functions against many diseases. These compounds include mainly large molecular weight (MW) compounds such as polysaccharides, dietary fibre and lipids. Mushroom polysaccharides have attracted great attention in food and pharmacology fields because of their biological activities. Polysaccharides vary in molecular weight, degree of branching and conformational structure. It has been reported that fine

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Keet, Lana. "Development of in vitro models to investigate the anti-inflammatory properties of Cyclopia Maculata and other South African herbal teas : a comparative study." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/97030.

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Thesis (MSc)--Stellenbosch University, 2015.<br>ENGLISH ABSTRACT: Chronic inflammation is suggested to contribute to cancer development and therefore a potential target for chemoprevention. In the skin, keratinocytes and macrophages play an integral part in acute and chronic inflammation, with interleukin 1-α (IL-1α) and tumor necrosis factor α (TNF-α) as key cytokines governing this process. Green tea (Camellia sinensis) and the South African herbal teas, rooibos (Aspalathus linearis) and honeybush (Cyclopia spp.) displayed antiinflammatory effects in mouse and human skin. To further in

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16

Jia, Xue Jing. "Physicochemical properties and pharmacological activities of polysaccharides from Rhynchosia minima root." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3952494.

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Stapleton, Graham Neil. "A study of the effects of sucralfate in the bile duct litigated pig peptic ulcer model with particular reference to the effects on the physico-chemical properties of gastric mucus and including comparisons with famotidine and misoprostol." Master's thesis, University of Cape Town, 1992. http://hdl.handle.net/11427/25727.

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Sucralfate is a drug that effectively heals duodenal, gastric and oesophageal ulcers. It is not absorbed systemically and it has been shown to act locally by coating the ulcer base. However when it was also shown to prevent stress ulcers and ethanolinduced gastric mucosa! lesions, it seemed likely that it acted in some way to improve the effectiveness of the gastric mucosa! barrier. Some investigators suggested that it did so by stimulating local prostaglandin release. The Slomiany group, on the basis of in vitro work on the effects of Sucralfate on pig gastric mucus, claimed that Sucralfate a

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Dysko, Anna Monika. "Synthesis and properties of oligonucleotides containing triazole backbone linkages and 2'-modifications for therapeutic applications." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:20fc1203-9751-4654-b497-5f4d97f874a1.

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Antisense oligonucleotides are short strands of DNA, which bind to their complementary mRNA target to prevent protein translation. Although conceptually appealing, for their practical use as drugs, these oligonucleotides must have better cellular uptake, resistance to enzymatic degradation, and target selectivity. In this work, new synthetic chemistry is established to prepare a novel group of chemically modified oligonucleotides. The anionic phosphodiester backbone is partially replaced with a neutral triazole and, at the same time, the 2'-position of the ribose sugar is functionalised with p

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Bland, Stephanie. "THERAPEUTIC AND SAFETY EVALUATION OF CURCUMIN'S ANTIMICROBIAL AND ANTI-INFLAMMATORY PROPERTIES ON CANINE AND EQUINE." OpenSIUC, 2016. https://opensiuc.lib.siu.edu/dissertations/1228.

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In total, four experiments were conducted to determine the therapeutic and safety effects of the nutraceutical, turmeric and its active ingredient curcumin on canine and equine. Two studies were conducted on client-owned, moderately arthritic canines, studying the therapeutic and safety effect of curcumin’s anti-inflammatory properties. In Exp. 1, two different dosages, 500 mg, SID of 95% curcumin and 250 mg, BID of 95% liposomal-curcumin, were evaluated in ten moderately arthritic dogs over five months. The dogs in the 95% curcumin group had an overall greater significance in pain reduction b

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Yeh, Chun-Liang. "Investigation of electrophoretic loading and enhanced mechanical properties of hydrogels for delivery of therapeutic proteins." Thesis, Queensland University of Technology, 2010. https://eprints.qut.edu.au/41771/1/Chun-Liang_Yeh_Thesis.pdf.

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Hydrogels, which are three-dimensional crosslinked hydrophilic polymers, have been used and studied widely as vehicles for drug delivery due to their good biocompatibility. Traditional methods to load therapeutic proteins into hydrogels have some disadvantages. Biological activity of drugs or proteins can be compromised during polymerization process or the process of loading protein can be really timeconsuming. Therefore, different loading methods have been investigated. Based on the theory of electrophoresis, an electrochemical gradient can be used to transport proteins into hydrogels. Theref

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Kwok, Hoi-shan, and 郭凱珊. "The comparison of biological properties of L- and D-enantiomeric antimicrobial peptides." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206507.

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Antibiotics have been used widely for the treatment of bacterial infections for over half a century. However, the emergence of resistance to antibiotics has aroused public health concern, leading to the development of antimicrobial peptides (AMPs) as potential alternative therapeutic agents against bacterial infections. AMPs are naturally found in many species and have important roles in our innate immune defense systems. AMPs are usually cationic amphipathic peptides with membrane destabilizing property. They have a relatively broad spectrum of antimicrobial activity and pathogens are less li

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Sumaya, Wael. "Fibrin clot properties and clinical outcomes in patients with acute coronary syndrome : an additional therapeutic target?" Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/20586/.

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23

Müller, Adrienne Carmel. "An investigation into the neuroprotective properties of acyclovir." Thesis, Rhodes University, 2006. http://hdl.handle.net/10962/d1003254.

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Accumulating evidence suggests that quinolinic acid has a role to play in disorders involving impairment of learning and memory. In the present study, the effect of the guanosine analogue antiherpetic, acyclovir, on quinolinic acid-induced spatial memory deficits was investigated, as well as some of the mechanisms which underlie this effect. Behavioural studies using a Morris water maze show that post-treatment of rats with acyclovir significantly improves spatial memory deficits induced by intrahippocampal injections of quinolinic acid. Histological analysis of the hippocampi show that the ef

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24

Polito, Anthony B. III. "Manipulation of Gold Nanorod Physicochemical Properties to Enhance Biocompatibility, Uptake and Intracellular Preservation of Optical Properties for Bio-Imaging and Plasmonic Photo-Therapeutic Applications." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1440598544.

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Naga, Nishal. "An investigation into the possible neuroprotective properties of phenytoin." Thesis, Rhodes University, 2002. http://eprints.ru.ac.za/2314/1/NAGA-MSc-TR03-77.pdf.

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Cerebral ischaemia, traumatic injury to the brain, inflammatory neurological disorders and HIV infections are amongst the most prevalent causes of neurodegeneration. Neuroprotective strategies are usually to limit the progressive secondary injury that generally occurs, thus limiting overall tissue damage. Neuroprotective strategies are usually to limit the progressive secondary injury that generally occurs, thus limiting overall tissue damage. Sodium channel blockers have been often used for this matter as they prevent the cascade of events culminating in free radical generation and eventual

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DALL, MAGRO EDUARDO. "Resistencia de uniao ao cisalhamento de dois sistemas adesivos em superficies dentinarias preparadas com laser de ER:YAG." reponame:Repositório Institucional do IPEN, 2001. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10861.

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Made available in DSpace on 2014-10-09T12:44:49Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:00:00Z (GMT). No. of bitstreams: 1 07303.pdf: 2160691 bytes, checksum: 2475a278645c388dd7f0a32d73f90b55 (MD5)<br>Dissertacao (Mestrado Profissionalizante em Lasers em Odontologia)<br>IPEN/D-MPLO<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP

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Sagbo, Idowu Jonas. "Phytochemical analysis and antibacterial properties of aqueous and ethanol extracts of Brachylaena elliptica (Thurb.) dc. and Brachylaena ilicifolia (Lam.) Phill & Schweick." Thesis, University of Fort Hare, 2015. http://hdl.handle.net/10353/d1021289.

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Resistance of human pathogenic bacterial strains results in selective pressure against known antibiotic. However, plant derived compounds that possess antibacterial potential are currently being investigated for treatment of wound infections in diabetic patients as they are inexpensive and non-toxic. Hence, this dissertation was designed to evaluate two medicinal plants (Brachylaena elliptica and Brachylaena ilicifolia) traditionally used in the treatment of various diseases such as diabetes, and its secondary complications in diabetic patients. The in vitro antioxidant activity of both plants

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Saha, Chaitrali. "Unravelling the therapeutic intervention of inflammation and cancer by Viscum album : understanding its anti-inflammatory and immunostimulatory properties." Thesis, Compiègne, 2015. http://www.theses.fr/2015COMP2210/document.

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Les préparations de Viscum album (VA), connu sous le nom vernaculaire de gui européen, sont fréquemment utilisées en support des traitements anticancéreux, principalement pour améliorer la qualité de vie des malades et réduire la croissance des tumeurs. Elles sont connues pour exercer des effets anti-tumoraux. Il existe de plus en plus de données scientifiques faisant état de liens étroits entre cancer et inflammation. Étant donné que la prostaglandine E2 (PGE2) induite par la cyclo-oxygénase 2 (COX-2) joue un rôle clef dans l’inflammation, j’ai exploré la régulation du système COX-2-PGE2 par

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Mann, Maryssa Gudrun Ailsa. "An investigation of the antimicrobial and antifouling properties of marine algal metabolites." Thesis, Rhodes University, 2008. http://hdl.handle.net/10962/d1007465.

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Prevention of the accumulation of undesirable biological material i.e. biofouling upon a solid surface requires the use of antifouling systems. The solid surface may be a contact lens, an off shore oil rig or a living organism. When chemicals are employed as a mechanism of defense against biofouling, the agents involved are known as antifouling agents. Marine algae must protect themselves from fouling organisms and it is thought that one of the mechanisms used by these organisms is the production of secondary metabolites with an array of biological activities. In vitro studies have shown numer

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Odeyemi, Samuel Wale. "A comparative study of the in vitro antidiabetic properties, cytotoxicity and mechanism of action of Albuca bracteata and Albuca setosa bulb extracts." Thesis, University of Fort Hare, 2015. http://hdl.handle.net/10353/3154.

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The search for cheap, non toxic and readily available antidiabetic drugs has been a challenge for researchers and the pharmaceutical industries. Diabetes mellitus is a metabolic disease characterized by defects in the synthesis of insulin and/or insensitivity to the action of insulin at the target cells. The disease has been on the increase mostly in developing countries where large proportions of the population have little access to good medical care due to either accessibility or non availability of synthetic drugs. This has led to the use of medicinal plants to treat diabetes because it is

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Cheng, Chi Yan. "Anti-arthritic properties of a herbal formula comprising Rosae Multiflorae Fructus and Lonicerae Japonicae Flos." HKBU Institutional Repository, 2016. https://repository.hkbu.edu.hk/etd_oa/311.

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Rheumatoid arthritis (RA), the most common autoimmune disease, affects billions of people worldwide. Conventional therapeutics do not provide satisfactory efficacy and even cause severe adverse reactions. Researchers are seeking new approaches for RA management. Toll-like receptor 4 (TLR4) signalling plays a pivotal role in the pathogenesis of RA, and has been proposed as a potential therapeutic target for RA. Chinese medicines are believed to be alternative options for conventional RA therapeutics. A herbal formula RL, consisting of Rosae Multiflorae Fructus and Lonicerae Japonicae Flos, has

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Wang, Di, and 王迪. "Molecular and biochemical characterization of therapeutic properties of paeoniae-glycyrrhiza decoction, a Chinese herbal preparation, against antipsychotic-associated hyperprolactinemia." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193412.

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Hyperprolactinemia (hyperPRL) is a highly prevalent adverse side effect in antipsychotic therapy as most antipsychotic drugs are dopamine D2 receptor antagonists. Peony-Glycyrrhiza Decoction (PGD, 芍藥甘草湯) is a classic Chinese herbal formula initially used to treat muscle pain and spasm. Our pilot clinical studies have confirmed the effectiveness of PGD in alleviating antipsychotic-induced hyperPRL in patients with schizophrenia. In the present study, we further examined the effects of PGD, its individual herbal preparations and major compounds in suppressing prolactin (PRL) hyperactivity in in

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Nguyen, Anh Dung. "Elaboration of an innovative protocol for measuring the mechanical properties of cell membranes for medical diagnostic and therapeutic applications." Thesis, Le Mans, 2020. http://www.theses.fr/2020LEMA1006.

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La mesure des propriétés mécaniques des membranes entourant les cellules vivantes pourraient révéler/refléter leur état physiologique, leur état pathologique ou l’influence d'un agent externe tel qu'un médicament ou un virus, ou encore la réponse à une stimulation ou à un protocole thérapeutique. Les principales techniques de mesure de ces propriétés présentent de nombreuses limitations notamment en termes de qualité, de fiabilité, de la rapidité de la mesure et du nombre d’acquisitions. Cette thèse est centrée sur l’utilisation du Mode Circulaire de Microscopie à Force Atomique ou MC-AFM en m

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Liu, Wai-ching, and 廖惠清. "Strontium incorporated materials in orthopaedics: gentamicin release in bone cement and scaffolds with highmechanical properties for tissue engineering." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B47234672.

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　　　Strontium (Sr) is not only widely studied for its compound as a drug for treating osteoporosis, but there is also a growing interest of its addition in orthopaedic biomaterials. Over the years, the development of orthopaedic biomaterials has already advanced to a new era in the search of resorbable and/or bioactive materials. Due to its anabolic and anti-resportive properties of Sr on bone regeneration as a drug, strontium has been extensively investigated for its potential in other orthopaedic applications. The purposes of this study were to investigate strontium containing hydroxyapat

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Kala, Shashwati. "Role of ginsenoside Rb1 and its metabolite compound K in attenuating chemoresistance and tumour-initiating properties of ovarian cancer cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/207178.

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Harris, Taahir. "Bambara groundnut (Vigna subterranean) from Mpumalanga province of South Africa: phytochemical and antimicrobial properties of seeds and product extracts." Thesis, Cape Peninsula University of Technology, 2017. http://hdl.handle.net/20.500.11838/2789.

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Thesis MTech (Food Technology))--Cape Peninsula University of Technology, 2017.<br>Bambara groundnut (Vigna subterranea) an indigenous legume cultivated in Sub-Saharan Africa has been proclaimed to have medicinal properties from communities and in rural areas. However, there is not enough scientific information to validate these claims. Therefore, this study aimed to identify possible medicinal properties of Bambara groundnut (BGN), by analysing the phytochemical and antimicrobial properties of BGN seed and product extracts from Mpumalanga province within South Africa. The BGN extracts (70% me

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Neves, Pedro David Oliveira. "Importância dos compostos fenólicos dos frutos na promoção da saúde." Master's thesis, [s.n.], 2015. http://hdl.handle.net/10284/5241.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>Quimicamente pode-se classificar os compostos fenólicos como fenóis simples ou polifenóis, com base no número de unidades de fenol existentes na molécula. Os compostos fenólicos são substâncias amplamente distribuídas na natureza, entre as quais aproximadamente 8000 já foram identificadas nas plantas. Este grande grupo faz parte dos constituintes de uma variedade de vegetais, frutas e produtos industrializados. De uma maneira ger

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Shiu, Hoi Ting. "Controlling whole blood activation and resultant clot properties on various material surfaces : a possible therapeutic approach for enhancing bone healing." Thesis, Queensland University of Technology, 2013. https://eprints.qut.edu.au/63628/1/Shiu_Ting_Thesis.pdf.

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Injured bone initiates the healing process by forming a blood clot at the damaged site. However, in severe damage, synthetic bone implants are used to provide structural integrity and restore the healing process. The implant unavoidably comes into direct contact with whole blood, leading to a blood clot formation on its surface. Despite this, most research in bone tissue engineering virtually ignores the important role of a blood clot in supporting healing. Surface chemistry of a biomaterial is a crucial property in mediating blood-biomaterials interactions, and hence the formation of the r

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Chellan, Nireshni. "The antidiabetic and antioxidant properties of Athrixia phylicoides aqueous extract : an in vitro and ex vivo assessment." Thesis, Stellenbosch : University of Stellenbosch, 2011. http://hdl.handle.net/10019.1/6612.

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Thesis (MScMedSc)--University of Stellenbosch, 2011.<br>ENGLISH ABSTRACT: Introduction: Athrixia phylicoides is an aromatic, indigenous shrub with high antioxidant content and numerous indigenous medicinal properties inferred by ingestion of an herbal brew of the plant. Commercialization of “bush tea” (derived from A. phylicoides) holds economic and developmental potential for indigenous communities provided the safety and efficacy of the herbal tea is established. Recently A. phylicoides has been shown by McGaw et al. (2007) to have similar antioxidant activity to Rooibos tea, and a unique, n

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Pringle, Nadine Alex. "Characterization of a glycated gelatin model to explore the therapeutic properties of macrofungi in diabetic wound healing: an in vitro study." Thesis, Nelson Mandela Metropolitan University, 2017. http://hdl.handle.net/10948/11992.

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Diabetic wounds frequently undergo impaired and prolonged wound healing due to a multitude of factors including hypoxia, impaired angiogenesis, hyperglycaemia, formation of ROS and AGEs, and infection - all of which may lead to cellular dysfunction. To date, however, treatment options for individuals suffering from impaired diabetic wound healing are limited, non-specific, and generally unsuccessful. The search for new and effective treatment strategies is severely hampered by the availability of adequately characterized screening models which comprehensively mimic the complexity of the diabet

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Yengkopiong, P. J. "The assessment of the therapeutic and toxicological properties of carpobrotus acinaciformis and schkuhria pinnata used in traditional medicine in South Africa." Thesis, University of Limpopo (Medunsa Campus), 2005. http://hdl.handle.net/10386/846.

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Boldrin, Paula Karina. "Avaliação das atividades mutagênica, pró-inflamatória e estrogênica de Machaerium hirtum e Crotalaria pallida /." Araraquara, 2013. http://hdl.handle.net/11449/95173.

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Orientador: Eliana Aparecida Varanda<br>Banca: Denise Crispim Tavares<br>Banca: Flávia Aparecida Resende<br>Resumo: A família Fabaceae tem ocorrência em toda faixa tropical e em regiões temperadas, sendo uma família que apresenta grande potencial econômico. Machaerium, um dos gêneros pertencente a esta família, tem sido utilizado para diversos fins, tais como a recomposição de áreas degradadas ou uso medicinal para o tratamento de diarréia, cólicas menstruais, tosse e aftas bucais. Já o gênero Crotalaria, tem sido empregado na agricultura como adubo verde no combate à erosão e também despertad

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Magcwebeba, Tandeka Unathi. "Chemopreventive properties of South African herbal teas, rooibos (Aspalathus linearis) and honeybush (Cyclopia spp) : mechanisms against skin carcinogenesis." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/85632.

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Thesis (PhD)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: The present study employed a two-phased approach to investigate the possible mechanisms involved in the chemopreventive properties of rooibos (Aspalathus linearis) and different honeybush species (Cyclopia spp.) in vitro. In the first phase, the effect of unfermented methanol and aqueous herbal tea extracts against the growth parameters (cell viability, proliferation and apoptosis) of normal (CRL 7761); premalignant (HaCaT); and malignant (CRL 7762) skin cells was evaluated and compared to green tea extracts. The predictive pote

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Boldrin, Paula Karina [UNESP]. "Avaliação das atividades mutagênica, pró-inflamatória e estrogênica de Machaerium hirtum e Crotalaria pallida." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/95173.

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Made available in DSpace on 2014-06-11T19:27:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-04-12Bitstream added on 2014-06-13T19:35:39Z : No. of bitstreams: 1 boldrin_pk_me_arafcf.pdf: 821120 bytes, checksum: 24da3e2629cace4da1696a044c5c3fdd (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>A família Fabaceae tem ocorrência em toda faixa tropical e em regiões temperadas, sendo uma família que apresenta grande potencial econômico. Machaerium, um dos gêneros pertencente a esta família, tem sido utilizado para diversos fins, tais como a recomposição de áreas

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BACHMANN, LUCIANO. "Estrutura e composicao do esmalte e da dentina tratados termicamente ou irradiados com lasers emissores no infravermelho." reponame:Repositório Institucional do IPEN, 2004. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11179.

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Made available in DSpace on 2014-10-09T12:49:16Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:00:00Z (GMT). No. of bitstreams: 1 09822.pdf: 14682529 bytes, checksum: b78ed1c4a8226797ef2bda81a2471100 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Tese(Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP<br>FAPESP:00/01102-1

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MOREIRA, ALEXANDRE A. "Avaliacao da adesao do cimento de ionomero de vidro a dentina irradiada com laser de Nd:YAG." reponame:Repositório Institucional do IPEN, 2001. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10977.

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MARRACCINI, TARSO M. "Estudo comparativo do condicionamento do esmalte e dentina para a adesao de resinas compostas com os lasers Er:YAG 2,94 micrometros e com o laser Co sub(2) de 9,6 micrometros." reponame:Repositório Institucional do IPEN, 2002. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11030.

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Pinzon-Arango, Paola A. "Investigating the effects of cranberry juice on the physicochemical properties of Escherichia coli for the prevention of urinary tract infections." Worcester, Mass. : Worcester Polytechnic Institute, 2008. http://www.wpi.edu/Pubs/ETD/Available/etd-010908-121947/.

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Oliveira, Fabrício Borges. "O ultra-som terapêutico adicionado à imobilização gessada nas propriedades mecânicas da reparação muscular pós-trauma por mecanismo de impacto." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/82/82131/tde-29032006-110757/.

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Desenvolvemos um instrumento capaz de provocar uma lesão muscular aguda por mecanismo de impacto, no músculo gastrocnêmio de ratas, através de um trauma direto e não-invasivo. Após a produção da lesão experimental avaliamos os efeitos do ultra-som terapêutico (UST), adicionado ou não à imobilização gessada, como forma de tratamento imediato à lesão muscular pela análise das propriedades mecânicas deste músculo. Foram utilizadas 68 ratas da raça Wistar, sendo divididas em 7 grupos experimentais da seguinte forma: Grupo 1 Controle intacto; Grupo 2 Sem tratamento efetivo, Grupo 3 Imobilizaç

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Sällqvist, Natanael. "Terapeuters val av hästen som terapeutisk resurs : En deskriptiv studie om terapeuters tankar om val av metod och hästen som terapeutisk resurs i hästunderstödd terapi." Thesis, Ersta Sköndal högskola, Institutionen för socialvetenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:esh:diva-4609.

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Fokus i studien ligger på terapeuters val av metod och synen på hästen som terapeutiskt resurs. Detta görs genom kvalitativ deskriptiv ansats. Terapeuterna intervjuas genom semistrukturerad intervjuguide med öppna frågor. Arthurs teori om vilka typer av terapeuter som, utifrån personlighet och epistemologiska uppfattningar, är disponerade till en viss typ av terapeutisk inriktning, användes för att försöka förklara varför de terapeuter som arbetar med HUT, väljer den metoden. Resultatet visar att terapeuternas val av HUT metod inte kunde förklaras genom Arthur's teori. Resultatet visar också a

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