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Journal articles on the topic 'And wound-healing properties'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Hillman, Prima F., Chaeyoung Lee, and Sang-Jip Nam. "Microbial Natural Products with Wound-Healing Properties." Processes 11, no. 1 (2022): 30. http://dx.doi.org/10.3390/pr11010030.

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Wound healing continues to pose a challenge in clinical settings. Moreover, wound management must be performed properly and efficiently. Acute wound healing involves multiple cell divisions, a new extracellular matrix, and the process of formation, such as growth factors and cytokines, which are released at the site of the wound to regulate the process. Any changes that disrupt the healing process could cause tissue damage and prolong the healing process. Various factors, such as microbial infection, oxidation, and inflammation, can delay wound healing. In order to counter these problems, util

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Green, A. E. "Wound healing properties of honey." British Journal of Surgery 75, no. 12 (1988): 1278. http://dx.doi.org/10.1002/bjs.1800751236.

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Choudhary, Vikram, and H. G. Shivakumar. "A REVIEW ON CURCUMIN: WOUND HEALING PROPERTIES AND BIOMARKERS OF WOUND HEALING." International Research Journal Of Pharmacy 9, no. 9 (2018): 1–5. http://dx.doi.org/10.7897/2230-8407.099179.

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Ibrahim, Nurul, Sok Wong, Isa Mohamed, et al. "Wound Healing Properties of Selected Natural Products." International Journal of Environmental Research and Public Health 15, no. 11 (2018): 2360. http://dx.doi.org/10.3390/ijerph15112360.

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Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have bee

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Li, Rongkai, Qinbing Qi, Chunhua Wang, Guige Hou, and Chengbo Li. "Self-Healing Hydrogels Fabricated by Introducing Antibacterial Long-Chain Alkyl Quaternary Ammonium Salt into Marine-Derived Polysaccharides for Wound Healing." Polymers 15, no. 6 (2023): 1467. http://dx.doi.org/10.3390/polym15061467.

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The development of hydrogels as wound dressings has gained considerable attention due to their promising ability to promote wound healing. However, in many cases of clinical relevance, repeated bacterial infection, which might obstruct wound healing, usually occurs due to the lack of antibacterial properties of these hydrogels. In this study, we fabricated a new class of self-healing hydrogel with enhanced antibacterial properties based on dodecyl quaternary ammonium salt (Q12)-modified carboxymethyl chitosan (Q12-CMC), aldehyde group- modified sodium alginate (ASA), Fe3+ via Schiff bases and

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Dodi, Gianina, Rosina E. Sabau, Bianca E. B. Crețu, and Ioannis Gardikiotis. "Exploring the Antioxidant Potential of Gellan and Guar Gums in Wound Healing." Pharmaceutics 15, no. 8 (2023): 2152. http://dx.doi.org/10.3390/pharmaceutics15082152.

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It is acknowledged that the presence of antioxidants boosts the wound-healing process. Many biopolymers have been explored over the years for their antioxidant potential in wound healing, but limited research has been performed on gum structures and their derivatives. This review aims to evaluate whether the antioxidant properties of gellan and guar gums and wound healing co-exist. PubMed was the primary platform used to explore published reports on the antioxidant wound-healing interconnection, wound dressings based on gellan and guar gum, as well as the latest review papers on guar gum. The

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Hong, Zhiwu, Lei Wu, Zherui Zhang, et al. "Self-Healing Supramolecular Hydrogels with Antibacterial Abilities for Wound Healing." Journal of Healthcare Engineering 2023 (February 9, 2023): 1–10. http://dx.doi.org/10.1155/2023/7109766.

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Wound healing due to skin defects is a growing clinical concern. Especially when infection occurs, it not only leads to impair healing of the wound but even leads to the occurrence of death. In this study, a self-healing supramolecular hydrogel with antibacterial abilities was developed for wound healing. The supramolecular hydrogels inherited excellent self-healing and mechanical properties are produced by the polymerization of N-acryloyl glycinamide monomers which carries a lot of amides. In addition, excellent antibacterial properties are obtained by integrating silver nanoparticles (Ag NPs

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Brown, Stuart J., Farhana Surti, Paul Sibbons, and Lilian Hook. "Wound healing properties of a fibrin-based dermal replacement scaffold." Biomedical Physics & Engineering Express 8, no. 1 (2021): 015025. http://dx.doi.org/10.1088/2057-1976/ac4176.

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Abstract When serious cutaneous injury occurs, the innate wound healing process attempts to restore the skin’s appearance and function. Wound healing outcome is affected by factors such as contraction, revascularisation, regeneration versus fibrosis and re-epithelialisation and is also strongly influenced by the pattern and extent of damage to the dermal layer. Dermal replacement scaffolds have been designed to substitute for lost tissue, provide a structure to promote dermal regeneration, and aid skin grafting, resulting in a superior healing outcome. In this study the wound healing propertie

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Alven, Sibusiso, Vuyolwethu Khwaza, Opeoluwa O. Oyedeji, and Blessing A. Aderibigbe. "Polymer-Based Scaffolds Loaded with Aloe vera Extract for the Treatment of Wounds." Pharmaceutics 13, no. 7 (2021): 961. http://dx.doi.org/10.3390/pharmaceutics13070961.

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The treatment of wounds is one challenging biomedical field due to delayed wound healing common in chronic wounds. Several factors delay wound healing, including microbial infections, malnutrition, underlying physiological conditions, etc. Most of the currently used wound dressing materials suffer from poor antimicrobial properties, poor biodegradability and biocompatibility, and weak mechanical performance. Plant extracts, such as Aloe vera, have attracted significant attention in wound management because of their interesting biological properties. Aloe vera is composed of essential constitue

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Firda, Rahmania, and Fawzy Ahmad. "Efficacy of Honey-Based Wound Dressing Versus Hydrogel-Based Wound Dressing in Wound Healing Process: A Literature Review." INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES 04, no. 05 (2024): 812–17. https://doi.org/10.5281/zenodo.11125857.

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<strong>Introduction:</strong> Wound dressing is a fundamental aspect of modern healthcare, encompassing a diverse range of materials and techniques aimed at optimizing the healing process while safeguarding against infection and further injury. By understanding the specific benefits of different types of wound dressings, healthcare professionals can optimize the healing process and improve patient outcomes   <strong>Methods:</strong> This literature review was compiled using information from various open access online databases. Data were collected and analyzed.   <strong>

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Jahan, Nusrat, Rifat Ara Neera, iffat Ara, Humayra Akhter Himu, and Jannatul Ferdush. "Development of Antimicrobial Textile Used to Dressing for Wound Healing." Journal of Natural Science and Textile Techonology (JNSTT) 2, no. 1 (2023): 32–38. https://doi.org/10.5281/zenodo.8275054.

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Ocimum basilicum plant has medicinal value and it has been used as a good source of ayurvedic medicine. This work presents the wound healing properties of dyed viscose and silk fabric with Ocimum basilicum plant extract by cold pad batch method. Cold pad batch dyeing technology was considered for incorporating antimicrobial properties that will support wound healing into viscose and silk fabric, whereas Ocimum basilicum plant extract was used as a natural antimicrobial agent. Both dyed antimicrobial textile dressings showed good wound healing properties, whereas silk dressing displayed better

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Mazurek, Łukasz, Mateusz Szudzik, Mateusz Rybka, and Marek Konop. "Silk Fibroin Biomaterials and Their Beneficial Role in Skin Wound Healing." Biomolecules 12, no. 12 (2022): 1852. http://dx.doi.org/10.3390/biom12121852.

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The skin, acting as the outer protection of the human body, is most vulnerable to injury. Wound healing can often be impaired, leading to chronic, hard-to-heal wounds. For this reason, searching for the most effective dressings that can significantly enhance the wound healing process is necessary. In this regard, silk fibroin, a protein derived from silk fibres that has excellent properties, is noteworthy. Silk fibroin is highly biocompatible and biodegradable. It can easily make various dressings, which can be loaded with additional substances to improve healing. Dressings based on silk fibro

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Kavish, P., R. Kalpana, and Vinay Kumar. "Doxycycline Drug Release Property of Glutaraldehyde Crosslinked Hydrogel." Journal of Pharmacy and Bioallied Sciences 16, Suppl 2 (2024): S1204—S1206. http://dx.doi.org/10.4103/jpbs.jpbs_541_23.

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ABSTRACT Delayed wound healing is one of the most common problems associated with diabetic patients. There are several factors associated with delayed wound healing. It has been observed that if not cured the wound healing takes a long time. This is the reason that researchers are engaged in developing sustainable, biodegradable, biocompatible, and effective wound-healing dressings. However, it has been observed that the traditional wound-healing bandages have drawbacks such as allergies and less efficiency in the absorption of wound exudate. To fill the gap, hydrogels have been developed rece

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Ghosh, Prasanta Kumar, and Anjali Gaba. "Phyto-Extracts in Wound Healing." Journal of Pharmacy & Pharmaceutical Sciences 16, no. 5 (2013): 760. http://dx.doi.org/10.18433/j3831v.

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Data generated through systematic investigation, carried out on the evaluation of phyto-extracts on wound healing research during the last 20 years have been compiled. About 450 plant species having wound healing properties have been identified. The present knowledge of the wound healing process comprise coagulation, inflammation, proliferation, formation and accumulation of fibrous tissues, collagen deposition, epithelialization, contraction of wound with formation of granulation tissues, remodeling and maturation. The constituents of the plant extracts modulate one or more of the above stage

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Abdulhameed, Ola Adil, and Haitham Mahmood Kadhim. "Exploring the Role of Pleurotus Ostreatus as an Ointment Formulation in Inducing Wound Healing in Mice Skin." Journal of Pharmacy and Bioallied Sciences 16, Suppl 1 (2024): S243—S246. http://dx.doi.org/10.4103/jpbs.jpbs_480_23.

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ABSTRACT Background: Natural compounds rich in secondary metabolites have gained attention as alternative therapies for wound healing due to their potential advantages over conventional treatments. Pleurotus ostreatus mushrooms have been identified for their wound-healing properties, including promoting neovascularization, epithelialization, and collagen synthesis. Material and Methods: This study aimed to investigate the wound-healing properties of different doses of topical Extract of Pleurotus ostreatus in albino mice using an excisional wound model. The experimental design involved adminis

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Chittoria, Ravi Kumar. "Biosilk bilayered scaffold Application in Wound bed Preparation of Thermal Burns Wound." Clinical Research and clinical Trials 10, no. 05 (2024): 01–04. http://dx.doi.org/10.31579/2693-4779/214.

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Haemostasis, inflammation, proliferation, and remodelling are the steps that comprise the complex biological process of wound healing. Chronic wounds often remain static in the inflammatory stage of wound healing beyond the expected duration and resist healing. Biosilk or biomodified silk dressing is believed to aid in accelerating the wound healing process. The combination bio functionalised silk matrix with silver oxide and Centella asiatica, a medicinal plant with wound healing properties, has been found to be effective in managing chronic non-healing wounds.

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17

Della Sala, Francesca, Gennaro Longobardo, Antonio Fabozzi, Mario di Gennaro, and Assunta Borzacchiello. "Hyaluronic Acid-Based Wound Dressing with Antimicrobial Properties for Wound Healing Application." Applied Sciences 12, no. 6 (2022): 3091. http://dx.doi.org/10.3390/app12063091.

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Wound healing is a naturally occurring process that can be aided by a wound dressing properly designed to assure an efficient healing process. An infection caused by several microorganisms could interfere with this process, delaying or even impairing wound healing. Hyaluronic acid (HA), a main constituent of the extracellular matrix (ECM) of a vertebrate’s connective tissue, represents a promising biomaterial for wound dressing thanks to its intrinsic biocompatibility, hydrophilicity and bacteriostatic properties. In this review, different and recent types of HA-based wound dressings endowed w

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Fedosov, Pavel, Vladimir Nikolaevsky, Yury Chernov, Anna Buzlama, Alexey Slivkin, and Svetlana Provotorova. "PRECLINICAL STUDY OF THE EFFICACY AND SAFETY OF WOUND HEALING GEL CONTAINING CHITOSAN, TAURINE AND ALLANTOIN." Research Results in Pharmacology 3, no. (2) (2017): 14–28. https://doi.org/10.18413/2313-8971-2017-3-2-14-28.

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Introduction: The paper deals with the problem of wound healing, which is considered to remain one of the most pressing challenges of the modern medicine, despite a large variety of wound healing preparations. This results from a high level of domestic and military traumatism of the population, and the fact that many registered medications do not meet the requirements for modern wound healing preparations. Objectives: To develop gel containing chitosan, taurine, allantoin, and to experimentally investigate its wound healing properties in pre-clinical studies on laboratory animals. Methods: The

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Gbedema, StephenY, Kisseih Emelia, Adu Francis, Annan Kofi, and Woode Eric. "Wound healing properties and kill kinetics ofClerodendron splendensG. Don, a ghanaian wound healing plant." Pharmacognosy Research 2, no. 2 (2010): 63. http://dx.doi.org/10.4103/0974-8490.62948.

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Ajith, Govindaraj, Ganesan Padmini Tamilarasi, Govindaraj Sabarees, et al. "Recent Developments in Electrospun Nanofibers as Delivery of Phytoconstituents for Wound Healing." Drugs and Drug Candidates 2, no. 1 (2023): 148–71. http://dx.doi.org/10.3390/ddc2010010.

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Wound healing is an unresolved therapeutic challenge for the medical community, as wound assessment and management is a complex procedure involving numerous factors that play a significant role in the healing process. Several factors, including bacterial infections, underlying conditions, malnutrition, obesity, aging, and smoking are the most frequent causes of a delayed wound-healing process. The shortcomings related to the currently used wound dressings include poor antimicrobial properties, weak mechanical features, poor biodegradability, biocompatibility, etc. Modern medicine has expanded

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Esa, Nur Eszaty Farain, Mohamed Nainar Mohamed Ansari, Saiful Izwan Abd Razak, et al. "A Review on Recent Progress of Stingless Bee Honey and Its Hydrogel-Based Compound for Wound Care Management." Molecules 27, no. 10 (2022): 3080. http://dx.doi.org/10.3390/molecules27103080.

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Stingless bee honey has a distinctive flavor and sour taste compared to Apis mellifera honey. Currently, interest in farming stingless bees is growing among rural residents to meet the high demand for raw honey and honey-based products. Several studies on stingless bee honey have revealed various therapeutic properties for wound healing applications. These include antioxidant, antibacterial, anti-inflammatory, and moisturizing properties related to wound healing. The development of stingless bee honey for wound healing applications, such as incorporation into hydrogels, has attracted researche

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Bakari, G. G., S. A. Mshamu, M. H. Ally, R. A. Max, and H. Bai. "In-vitro Wound Healing Properties of Commiphora swynnertonii Resinous Extracts." Tanzania Veterinary Journal 38 (September 4, 2021): 32–37. http://dx.doi.org/10.4314/tvj.v38i1.6s.

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Wound healing is a complex multicellular process involving many cell types which include; inflammatory cells, endothelial cells, fibroblasts and keratinocytes. The process involves an orderly sequence of events with four overlapping phases namely; haemostasis, inflammatory, proliferation and remodeling phases. The process can be facilitated by the use of wound healing agents including herbal remedies from plants. In this study the main objective was to evaluate the in vitro wound healing activity of the resin obtained from Commiphora swynnertonii (C.swynnertonii). First the NIH -3T3 cells viab

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Sri Venkatesh, Uriti, Vamseedhar Annam, Aruna Kumari Nakkella, Abhijit S. Welankiwar, and Pradyumna S. Keche. "Nano Materials for Wound Healing." Journal of Neonatal Surgery 14, no. 3 (2025): 186–97. https://doi.org/10.52783/jns.v14.2213.

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Wound healing is a complex biological process involving multiple cellular and molecular mechanisms, which can be significantly enhanced through advanced therapeutic approaches. In recent years, nanomaterials have emerged as promising candidates for accelerating wound healing due to their unique physicochemical properties, biocompatibility, and antimicrobial effects. This paper explores the role of various nanomaterials, including metal nanoparticles, carbon-based nanomaterials, polymeric nanoparticles, and nanocomposites, in promoting tissue regeneration, reducing infection rates, and improvin

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Patil, Tejal V., Dinesh K. Patel, Sayan Deb Dutta, Keya Ganguly, Aayushi Randhawa, and Ki-Taek Lim. "Carbon Nanotubes-Based Hydrogels for Bacterial Eradiation and Wound-Healing Applications." Applied Sciences 11, no. 20 (2021): 9550. http://dx.doi.org/10.3390/app11209550.

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Biocompatible nanomaterials have attracted enormous interest for biomedical applications. Carbonaceous materials, including carbon nanotubes (CNTs), have been widely explored in wound healing and other applications because of their superior physicochemical and potential biomedical properties to the nanoscale level. CNTs-based hydrogels are widely used for wound-healing and antibacterial applications. CNTs-based materials exhibited improved antimicrobial, antibacterial, adhesive, antioxidants, and mechanical properties, which are beneficial for the wound-healing process. This review concisely d

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Sneha, A. Vikhe Abhishek R. Putale Prashant M. Rane Rohit D. Nagare Aman S. Pinjari. "Formulation Development & Evaluation Of Herbal Cream For Wound Healing Activity." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 610–15. https://doi.org/10.5281/zenodo.11186336.

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This study focuses on the development and evaluation of a novel wound healing cream aimed at promoting efficient wound repair and tissue regeneration. The cream formulation includes key ingredients known for their therapeutic properties, including anti-inflammatory, antimicrobial, and skin regeneration-promoting agents. Preliminary results indicate that the wound healing cream exhibits promising properties, including significant antimicrobial activity, enhanced cell migration and proliferation, reduced inflammation, and accelerated wound closure rates compared to control groups. Histological a

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Mirrezaei, Neda, Rezvan Yazdian-Robati, Fatemeh Oroojalian, Amirhossein Sahebkar, and Maryam Hashemi. "Recent Developments in Nano-Drug Delivery Systems Loaded by Phytochemicals for Wound Healing." Mini-Reviews in Medicinal Chemistry 20, no. 18 (2020): 1867–78. http://dx.doi.org/10.2174/1389557520666200807133022.

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Wound healing is a multi-stage process during which a cascade of molecular and cellular events collaborate to restore the damaged tissue to its healthy state. The inability of the available therapies to effectively heal the wounds has imposed major problems on healthcare systems. Therefore, developing novel therapeutic modalities capable of enhancing wound healing process with no/or limited scar formation is of more importance. Different studies have investigated the potential of phytochemicals on the wound healing process. They have shown to exert anti-inflammatory, antioxidant, and antibacte

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Grafakou, Maria-Eleni, Aggeliki Diamanti, Eleytheria Simirioti, et al. "Wound Healing Effects from 3 Hypericum spp. Essential Oils." Planta Medica International Open 8, no. 02 (2021): e69-e77. http://dx.doi.org/10.1055/a-1492-3634.

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Abstract Hypericum species have a long-term use as wound healing agents, with the most common preparation being the infused oil from the aerial parts. It contains naphthodianthrones, phloroglucinols, and essential oil. An extensive literature survey shows that, unlike napthodianthrones and phloroglucinols, essential oils from Hypericum spp. have not yet been evaluated for their wound healing efficacy. The present study aims to assess the wound healing efficacy of essential oils from H. perforatum, a plant recognized in European Pharmacopoeia for having wound healing properties, as well from 2

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Orjon Rroji and Admir Jançe. "Medicinal herbs in Albania: A treasure that we should preserve." GSC Biological and Pharmaceutical Sciences 32, no. 1 (2025): 215–21. https://doi.org/10.30574/gscbps.2025.32.1.0280.

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The aim of the present review is to highlight the significance and therapeutic benefits of medicinal herbs used for medical purposes. A comprehensive literature search was conducted using major scientific databases, including Scopus, PubMed, ScienceDirect, and Google Scholar, to identify relevant published studies. The therapeutics effects of Salvia officinalis, Papaver rhoeas, Hypericum perforatum, Oleum olivarum, Spartium junceum, honey (Mel) and Propolis have been described in this review. We summarized the therapeutic effects of each medicinal herb described and we could say that Salvia of

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Shweta, Chandra. "Efficacy and Mechanisms of Karanja Ghrita in Wound Healing: An Ayurvedic Perspective." International Journal of Ayurveda360 1, no. 4 (2025): 230–42. https://doi.org/10.5281/zenodo.14887428.

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Abstract <strong>Introduction:</strong> Wound healing is a critical process in clinical care, where traditional therapies, such as those derived from Ayurveda, offer significant benefits. <em>Karanja Ghrita</em>, a formulation combining <em>Karanja </em>(Pongamia pinnata) oil and ghee, is traditionally used in <em>Ayurvedic</em> practices for its wound healing properties. This review explores its efficacy and underlying mechanisms in wound management. <strong>Methods: </strong> The paper examines the <em>Ayurvedic</em> principles of wound healing, which include the stages of <em>dushta vrana</

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Yao, Han-Yun, Hong-Ru Lin, Geng-Pin Sue, and Yiu-Jiuan Lin. "Chitosan-based hydrogels prepared by UV polymerization for wound dressing." Polymers and Polymer Composites 27, no. 3 (2019): 155–67. http://dx.doi.org/10.1177/0967391118820477.

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Chitosan-based hydrogels were prepared by grafting with poly(acrylic acid) (PAA) and poly(hydroxyethyl methacrylate) (pHEMA) through ultraviolet polymerization to further improve its hydrophilic nature and enhance its mechanical properties. The epidermal growth factor (EGF) was incorporated inside the hydrogels to stimulate the wound healing. The physical characterization of chitosan-PAA-pHEMA hydrogel indicates that it is highly hydrophilic with adequate properties for wound dressing purpose. The biological characterization shows that chitosan-based hydrogel retains its thrombogenic and antib

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Chelu, Mariana, Adina Magdalena Musuc, Monica Popa, and Jose Calderon Moreno. "Aloe vera-Based Hydrogels for Wound Healing: Properties and Therapeutic Effects." Gels 9, no. 7 (2023): 539. http://dx.doi.org/10.3390/gels9070539.

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Aloe vera-based hydrogels have emerged as promising platforms for the delivery of therapeutic agents in wound dressings due to their biocompatibility and unique wound-healing properties. The present study provides a comprehensive overview of recent advances in the application of Aloe vera-based hydrogels for wound healing. The synthesis methods, structural characteristics, and properties of Aloe vera-based hydrogels are discussed. Mechanisms of therapeutic agents released from Aloe vera-based hydrogels, including diffusion, swelling, and degradation, are also analyzed. In addition, the therape

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Tyavambiza, Caroline, Mervin Meyer, and Samantha Meyer. "Cellular and Molecular Events of Wound Healing and the Potential of Silver Based Nanoformulations as Wound Healing Agents." Bioengineering 9, no. 11 (2022): 712. http://dx.doi.org/10.3390/bioengineering9110712.

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Chronic wounds are a silent epidemic threatening the lives of many people worldwide. They are associated with social, health care and economic burdens and can lead to death if left untreated. The treatment of chronic wounds is very challenging as it may not be fully effective and may be associated with various adverse effects. New wound healing agents that are potentially more effective are being discovered continuously to combat these chronic wounds. These agents include silver nanoformulations which can contain nanoparticles or nanocomposites. To be effective, the discovered agents need to h

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Wang, Sheng-Lan, Jia-Jun Zhuo, Shou-Min Fang, Wei Xu, and Quan-You Yu. "Silk Sericin and Its Composite Materials with Antibacterial Properties to Enhance Wound Healing: A Review." Biomolecules 14, no. 6 (2024): 723. http://dx.doi.org/10.3390/biom14060723.

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Wound infections may disrupt the normal wound-healing process. Large amounts of antibiotics are frequently used to prevent pathogenic infections; however, this can lead to resistance development. Biomaterials possessing antimicrobial properties have promising applications for reducing antibiotic usage and promoting wound healing. Silk sericin (SS) has been increasingly explored for skin wound healing applications owing to its excellent biocompatibility and antioxidant, antimicrobial, and ultraviolet-resistant properties. In recent years, SS-based composite biomaterials with a broader antimicro

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Morales-González, Maria, Luis Eduardo Díaz, Carlos Dominguez-Paz, and Manuel F. Valero. "Insights into the Design of Polyurethane Dressings Suitable for the Stages of Skin Wound-Healing: A Systematic Review." Polymers 14, no. 15 (2022): 2990. http://dx.doi.org/10.3390/polym14152990.

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Dressings made with polyurethanes have been found to exhibit good and varied biological properties that make them good candidates for this application. However, as has been seen, the wound-healing process is complex, which includes four different stages. So far, the design and evaluation of polyurethane for wound dressing has focused on achieving good properties (mechanical, physicochemical, and biological), but each of them separates from the others or even directed at only one of the stages of skin wound-healing. Therefore, the aim of this systematic review is to explore the applications of

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Sun, Zhenghua, Hao Xiong, Tengfei Lou, et al. "Multifunctional Extracellular Matrix Hydrogel with Self-Healing Properties and Promoting Angiogenesis as an Immunoregulation Platform for Diabetic Wound Healing." Gels 9, no. 5 (2023): 381. http://dx.doi.org/10.3390/gels9050381.

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Treating chronic wounds is a global challenge. In diabetes mellitus cases, long-time and excess inflammatory responses at the injury site may delay the healing of intractable wounds. Macrophage polarization (M1/M2 types) can be closely associated with inflammatory factor generation during wound healing. Quercetin (QCT) is an efficient agent against oxidation and fibrosis that promotes wound healing. It can also inhibit inflammatory responses by regulating M1-to-M2 macrophage polarization. However, its limited solubility, low bioavailability, and hydrophobicity are the main issues restricting i

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Budai-Szűcs, Mária, Marco Ruggeri, Angela Faccendini, et al. "Electrospun Scaffolds in Periodontal Wound Healing." Polymers 13, no. 2 (2021): 307. http://dx.doi.org/10.3390/polym13020307.

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Periodontitis is a set of inflammatory conditions affecting the tissues surrounding the teeth predominantly sustained by bacterial infections. The aim of the work was the design and the development of scaffolds based on biopolymers to be inserted in the periodontal pocket to restore tissue integrity and to treat bacterial infections. Nanofibrous scaffolds were prepared by means of electrospinning. Gelatin was considered as base component and was associated to low and high molecular weight chitosans and alginate. The scaffolds were characterized by chemico–physical properties (morphology, solid

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Hosseinkhani, Ayda, Maryam Falahatzadeh, Elahe Raoofi, and Mohammad M. Zarshenas. "An Evidence-Based Review on Wound Healing Herbal Remedies From Reports of Traditional Persian Medicine." Journal of Evidence-Based Complementary & Alternative Medicine 22, no. 2 (2016): 334–43. http://dx.doi.org/10.1177/2156587216654773.

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Research on wound healing agents is a developing area in biomedical sciences. Traditional Persian medicine is one of holistic systems of medicine providing valuable information on natural remedies. To collect the evidences for wound-healing medicaments from traditional Persian medicine sources, 5 main pharmaceutical manuscripts in addition to related contemporary reports from Scopus, PubMed, and ScienceDirect were studied. The underlying mechanisms were also saved and discussed. Totally, 65 herbs used in traditional Persian medicine for their wound healing properties was identified. Related an

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Oprita, Elena Iulia, Andreea Iosageanu, and Oana Craciunescu. "Natural Polymeric Hydrogels Encapsulating Small Molecules for Diabetic Wound Healing." Gels 9, no. 11 (2023): 867. http://dx.doi.org/10.3390/gels9110867.

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Diabetes is a condition correlated with a high number of diagnosed chronic wounds as a result of a complex pathophysiological mechanism. Diabetic chronic wounds are characterized by disorganized and longer stages, compared to normal wound healing. Natural polymer hydrogels can act as good wound dressings due to their versatile physicochemical properties, represented mainly by high water content and good biocompatibility. Natural bioactive hydrogels are polymers loaded with bioactive compounds providing antibacterial and antioxidant properties, modulation of inflammation and adherence to wounde

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Al-Gharbawi, Hussein Shundi Alhajj, Marwan Saleh Mahdi, Mustafa Naeem Nuhair Al-sarray, and Sajjad Jawad Kadhi Al-sarray. "Antibacterial activity and wound healing properties of chitosan ana nanoparticle chitosan in rat." Experimental and Theoretical NANOTECHNOLOGY 9, S (2025): 27–38. https://doi.org/10.56053/9.s.27.

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This study investigates the antibacterial and wound healing properties of chitosan and chitosan nanoparticles in a rat model. Twenty adult male rats are divided into two groups: one group received chitosan treatment, and the other received chitosan nanoparticle treatment. Each rat had two skin slits, which are dried over seven days. Wound healing is estimated through histopathological and microbiological duties. The findings tell that chitosan nanoparticles significantly develop wound healing and exhibit bigger antibacterial activity compared to traditional chitosan, representing their potenti

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Kasouni, Athanasia I., Theodoros G. Chatzimitakos, Constantine D. Stalikas, Theoni Trangas, Alexandra Papoudou-Bai, and Anastassios N. Troganis. "The Unexplored Wound Healing Activity of Urtica dioica L. Extract: An In Vitro and In Vivo Study." Molecules 26, no. 20 (2021): 6248. http://dx.doi.org/10.3390/molecules26206248.

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Wound healing is a great challenge in many health conditions, especially in non-healing conditions. The search for new wound healing agents continues unabated, as the use of growth factors is accompanied by several limitations. Medicinal plants have been used for a long time in would healing, despite the lack of scientific evidence veryfying their efficacy. Up to now, the number of reports about medicinal plants with wound healing properties is limited. Urtica dioica L. is a well-known plant, widely used in many applications. Reports regarding its wound healing potential are scant and sparse.

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Allu, Ishita, Ajay Kumar Sahi, Pooja Kumari, Karunya Sakhile, Alina Sionkowska, and Shravanya Gundu. "A Brief Review on Cerium Oxide (CeO2NPs)-Based Scaffolds: Recent Advances in Wound Healing Applications." Micromachines 14, no. 4 (2023): 865. http://dx.doi.org/10.3390/mi14040865.

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The process of wound healing is complex and involves the interaction of multiple cells, each with a distinct role in the inflammatory, proliferative, and remodeling phases. Chronic, nonhealing wounds may result from reduced fibroblast proliferation, angiogenesis, and cellular immunity, often associated with diabetes, hypertension, vascular deficits, immunological inadequacies, and chronic renal disease. Various strategies and methodologies have been explored to develop nanomaterials for wound-healing treatment. Several nanoparticles such as gold, silver, cerium oxide and zinc possess antibacte

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Jain, UK, and Nilesh Gupta. "Prominent wound healing properties of indigenous medicines." Journal of Natural Pharmaceuticals 1, no. 1 (2010): 2. http://dx.doi.org/10.4103/2229-5119.73579.

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Antonov, S. F., E. V. Kryzhanovskaya, Yu I. Filippov, S. M. Shinkarev, and M. A. Frolova. "Study of wound-healing properties of chitosan." Russian Agricultural Sciences 34, no. 6 (2008): 426–27. http://dx.doi.org/10.3103/s1068367408060190.

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Mohamed, Seema, Mary D. Nadijcka, and Victor A. Hanson. "Wound Healing Properties of Cimetidine in Vitro." Drug Intelligence & Clinical Pharmacy 20, no. 12 (1986): 973–75. http://dx.doi.org/10.1177/106002808602001212.

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Cimetidine was one of a variety of drugs frequently given to surgical patients perioperatively tested for their effect on gap closure of wounded monolayers of human fascia cells in vitro. Cimetidine-treated cultures closed faster and had greater cell proliferation than controls. Closure of cimetidine-treated cultures occurred at six hours compared to ten hours in controls. Cimetidine concentrations of 1000 μg/ml resulted in 13.5 ± 0.67 (SEM) × 104 cells/cm2 at six hours compared to 7.9 ± 0.48 times 104 cells/cm2 in controls (p<0.05); the area covered by cells was 6.5 ± 0.02 mm2 in treated c

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Alven, Sibusiso, Buhle Buyana, Zizo Feketshane, and Blessing Atim Aderibigbe. "Electrospun Nanofibers/Nanofibrous Scaffolds Loaded with Silver Nanoparticles as Effective Antibacterial Wound Dressing Materials." Pharmaceutics 13, no. 7 (2021): 964. http://dx.doi.org/10.3390/pharmaceutics13070964.

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The treatment of wounds is expensive and challenging. Most of the available wound dressings are not effective and suffer from limitations such as poor antimicrobial activity, toxicity, inability to provide suitable moisture to the wound and poor mechanical performance. The use of inappropriate wound dressings can result in a delayed wound healing process. Nanosize range scaffolds have triggered great attention because of their attractive properties, which include their capability to deliver bioactive agents, high surface area, improved mechanical properties, mimic the extracellular matrix (ECM

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Sheidu, Azeez Raji, Abdulkadir Umar Zezi, Abubakar Ahmed, Ben Ahmed Chindo, and Garba Mohammed Magaji. "Antimicrobial and wound healing properties of the methanol extract of Ficus platyphylla Del. (Moraceae) stem bark." Journal of Pharmacy & Bioresources 17, no. 2 (2021): 121–30. http://dx.doi.org/10.4314/jpb.v17i2.6.

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Ficus platyphylla (Fp) has been used in Nigerian traditional medicine for the management of pain, ulcer, wound, epilepsy and inflammation. The efficacy of its gum from the stem bark for the management of wound has been widely acclaimed among the Hausa communities of Northern Nigeria and therefore, this study was aimed at examining the antimicrobial and wound healing potential of methanol extract of F. platyphylla stem bark (MEFpSB) in order to provide scientific basis for its antimicrobial and wound healing properties. Preliminary phytochemical screening was done and antimicrobial activity usi

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Dospra, Maria, Panagoula Pavlou, Spyridon Papageorgiou, and Athanasia Varvaresou. "Recent Studies on the Healing Properties of Eicosapentaenoic Acid." Applied Sciences 14, no. 13 (2024): 5884. http://dx.doi.org/10.3390/app14135884.

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Patients with diabetes, the elderly, and those who have certain inherited conditions are particularly vulnerable to atypical wound healing with lingering repercussions. Remarkably, the current remedies are insufficient since, despite the plethora of wound healing options, only limited efficacy is observed. This review is a bibliographic survey on eicosapentaenoic acid and its healing effects. It has been investigated in terms of its source of origin, structure, physico-chemical properties, and studies where healing action is demonstrated. Fatty acids, found in all layers of the skin, modify ce

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Sallehuddin, Nusaibah, Abid Nordin, Ruszymah Bt Hj Idrus, and Mh Busra Fauzi. "Nigella sativa and Its Active Compound, Thymoquinone, Accelerate Wound Healing in an In Vivo Animal Model: A Comprehensive Review." International Journal of Environmental Research and Public Health 17, no. 11 (2020): 4160. http://dx.doi.org/10.3390/ijerph17114160.

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Nigella sativa (NS) has been reported to have a therapeutic effect towards skin wound healing via its anti-inflammatory, tissue growth stimulation, and antioxidative properties. This review examines all the available studies on the association of Nigella sativa (NS) and skin wound healing. The search was performed in Medline via EBSCOhost and Scopus databases to retrieve the related papers released between 1970 and March 2020. The principal inclusion criteria were original article issued in English that stated wound healing criteria of in vivo skin model with topically applied NS. The search d

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Yusmin, Ahmadi, and Norhayati Ahmad. "EFFECT OF THYMOQUINONE ON WOUND HEALING IN ALLOXAN-INDUCED DIABETIC RATS." Asian Journal of Pharmaceutical and Clinical Research 10, no. 9 (2017): 242. http://dx.doi.org/10.22159/ajpcr.2017.v10i9.18951.

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Objective: Nigella sativa and its active constituent thymoquinone (TQ) have been extensively documented for its pharmacological values, but its application in wound healing in particular in a diabetic wound healing model is less documented.Methods: In our study, alloxan-induced diabetic rats were used as a chronic delayed wound model and topical administration of TQ 10% w/v were used to assess the role and function of TQ in wound healing through wound contraction and histological analysis.Results: Although statistically insignificant, we found out that TQ accelerated wound healing in post-woun

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Kannan, Madhumita, R. Kalpana, and Vinay Kumar. "Sodium Alginate Chitosan Crosslinked Hydrogel Amoxycillin Absorption Properties." Journal of Pharmacy and Bioallied Sciences 16, Suppl 2 (2024): S1161—S1163. http://dx.doi.org/10.4103/jpbs.jpbs_511_23.

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ABSTRACT Wound healing refers to the replacement of destroyed or damaged tissue of a living organism by newly produced tissue, and the time taken is known as wound regeneration time. Wound care is a major challenging biomedical field due to the delayed healing process or delayed wound regeneration time. The factors responsible for delayed wound healing are poor oxygen flow, less exposure to moisture, diseases such as diabetes and cancer, etc., Wound dressings that are formulated from biopolymers such as chitosan, chitin, and cellulose have properties such as biocompatibility (compatible with l

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