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1

Scavée, V., S. Theys, and J.-C. Schoevaerdts. "Surgery of varicose veins with transilluminated powered mini-phlebectomy: clinical experience." Phlebology: The Journal of Venous Disease 18, no. 2 (2003): 97–99. http://dx.doi.org/10.1258/026835503321895415.

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The authors report their experience with a new surgical technique, the transilluminated powered mini-phlebectomy (Trivex' System, Smith & Nephew Inc, Andover, USA), to remove primary varicose veins. There were 70 patients, 50 women and 20 men, with a mean age of 52 ± 9 years. The average operating time was 56 ± 8 min (range 30–75 min). The mean number of incisions was five (range 2–8). The postoperative pain, cosmetic scores and all complications were evaluated prospectively.
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Roubille, François. "Risk Factors, Comorbidities, and Prevention of Cardiovascular Diseases: Don’t Forget the Primary Cause!" Journal of Clinical Medicine 13, no. 22 (2024): 6652. http://dx.doi.org/10.3390/jcm13226652.

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Cardiovascular diseases (CVDs) remain a leading cause of mortality worldwide. Despiteinnovative treatments, both pharmacological and interventional, CVDs continue toprogress. This is largely due to the increased incidence of diseases such as diabetes andother well-established cardiovascular risk factors, as well as cumulative comorbidities andemerging risk factors.
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Erdemir, Ebru Olgun, Abdulkadir Şengün, and Mustafa Ülker. "Cytotoxicity of Mouthrinses on Epithelial Cells by Micronucleus Test." European Journal of Dentistry 01, no. 02 (2007): 080–85. http://dx.doi.org/10.1055/s-0039-1698318.

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ABSTRACTObjectives: To determine the cytotoxicity of three commercial mouthrinses Klorhex, Andorex and Tanflex on buccal epithelial cells using micronucleus (MN) test.Materials and Methods: 28 patients with aged 16-24 undergone three mouthrinses’ application were analyzed before and after one week exposure. Physiologic saline was used for the control group. The MN incidence was scored in the buccal epithelial of each participants. The difference in pre- and posttreatment after one week incidence of MN and plaque (PI) and gingival indices (GI) was compared by non-parametric statistical tests.Re
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Wentzel, Jeanette, Cory Gall, Mark Bourn, Juan De Beer, Ferreira du Plessis, and Geoffrey T. Fosgate. "Carnivore Detection at the Domestic/Wildlife Interface within Mpumalanga Province, South Africa." Animals 11, no. 9 (2021): 2535. http://dx.doi.org/10.3390/ani11092535.

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South African protected areas account for 8% of the total landmass according to World Bank indicators. Effective conservation of biodiversity in protected areas requires the development of specific reserve management objectives addressing species and disease management. The primary objective of the current study was to identify predictors of carnivore detection in an effort to inform carnivore species management plans on Andover and Manyeleti nature reserves in South Africa. A limited number of camera traps were placed randomly using a grid system. Species detection data were analysed using mi
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Gildea, Spike, and Doris Payne. "Is Greenberg's "Macro-Carib" viable?" Boletim do Museu Paraense Emílio Goeldi. Ciências Humanas 2, no. 2 (2007): 19–72. http://dx.doi.org/10.1590/s1981-81222007000200003.

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In his landmark work Language in the Americas, Greenberg (1987) proposed that Macro-Carib was one of the major low-level stocks of South America, which together with Macro-Panoan and Macro-Ge-Bororo were claimed to comprise the putative Ge-Pano-Carib Phylum. His Macro-Carib includes the isolates Andoke and Kukura, and the Witotoan, Peba-Yaguan, and Cariban families. Greenberg's primary evidence came from person-marking paradigms in individual languages, plus scattered words from individual languages collected into 79 Macro-Carib 'etymologies' and another 64 Amerind 'etymologies'. The goal of t
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Kahlon, Rubab Zafar, and Ibtisam Butt. "Assessment of Forest Resource Exploitation in the Rural Communities of District Jhelum, Pakistan." International Journal of Economic and Environmental Geology 10, no. 3 (2019): 16–21. http://dx.doi.org/10.46660/ijeeg.vol10.iss3.2019.302.

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18 October, 2019 Accepted: 25 October, 2019Abstract: Forest resources are deteriorating and experiencing decline around the globe due to unsustainable use andover exploitation. The present study was an attempt to determine the relationship between human activities, forestresource utilization, extraction methods and practices of forest resource exploitation in the district Jhelum of Pakistan.For this purpose, primary sources of data were used which were collected from 8 villages through structuredquestionnaire and tabulated in Microsoft Excel 365 and SPSS 22 was used for multiple linear regress
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Kahlon, Rubab Zafar, and Ibtisam Butt. "Assessment of Forest Resource Exploitation in the Rural Communities of District Jhelum, Pakistan." International Journal of Economic and Environmental Geology 10, no. 3 (2019): 16–21. http://dx.doi.org/10.46660/ojs.v10i3.302.

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18 October, 2019 Accepted: 25 October, 2019Abstract: Forest resources are deteriorating and experiencing decline around the globe due to unsustainable use andover exploitation. The present study was an attempt to determine the relationship between human activities, forestresource utilization, extraction methods and practices of forest resource exploitation in the district Jhelum of Pakistan.For this purpose, primary sources of data were used which were collected from 8 villages through structuredquestionnaire and tabulated in Microsoft Excel 365 and SPSS 22 was used for multiple linear regress
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Sokhib, Rashidov Zamon oʻgʻli Muhammadrizo Rasulov Doniyorbek o'g'li Ferangiz Fayzullaeva Bakhtiyorovna Sardorbek Ergashev Nazarali oʻgʻli Diyorbek Alqorov Shavkat oʻgʻli. "DRUGS THAT REDUCE GASTRIC SECRETION, THE NEED AND PROSPECTS FOR THEIR USE." American Journal of Advanced Scientific Research (AJASR) 2, no. 9 (2025): 382–90. https://doi.org/10.5281/zenodo.15564904.

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The most common treatment for GERD is still medical therapy.Although interest in GERD drug development has decreased in recent years, mainlybecause most proton pump inhibitors (PPIs) have been converted to generic andover-the-counter compounds, there are still many unmet needs in GERD. Potenthistamine type 2 receptor antagonists, extended release PPIs, PPI combinations,potassium-competitive acid blockers, prokinetics, mucosal protectants, andesophageal pain modulators have been the focus of drug development. It is likelythat these compounds will be niched for specific unmet needs in GERD rathe
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Nitin, Arora1 Satyam Gupta2 Satyam Sareen3 Shahzeb Rizvi4 &. Alaknanda Ashok5. "EFFICIENTLY DATA MANAGEMENT USING MODIFIED B-TREE ALGORITHM." GLOBAL JOURNAL OF ENGINEERING SCIENCE AND RESEARCHES 6, no. 1 (2019): 158–63. https://doi.org/10.5281/zenodo.2549709.

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Main memory and secondary memory are different types of memory resources, as both of them have different properties and characteristics. It is often hard to load a large size of datasets into the main memory due to its cost and secondary memory can hold a large amount of data but the access time is comparatively slower than main memory. That’s why datasets reside in secondary storage HDDs, Magnetic tapes, etc. To process such size of datasets, a required part of datasets is retrieved from secondary storage and is placed in the internal memory for processing with the help of data-structur
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Zeidan, Muna. "Factors Associated with Anemia in A sample of Pregnant Women Attending Primary Health Centers." Iraqi National Journal of Nursing Specialties 26, no. 3 (2013): 20–29. http://dx.doi.org/10.58897/injns.v26i3.184.

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Objective (s): To determine proportion of anemia among sample of Pregnant women. To identify factorsassociated with the anemia (Maternal age, maternal education, gestational age, parity, gravidity, birthinterval, smoking, taking iron supplements and dietary habits).Methodology: A cross-sectional study conducted at Al- washash & Bab-almoadham primary health carecenters. The sample was selected by (non-probability convenient sampling) and sample size was (550).The study started from 1st March 2011 to 30th of March 2012. The data was collected by direct interviewusing special questionnaire to
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Mansoor, Nurulhana Shaikh, Farnaza Ariffin, Leny Suzana Suddin, and Zati Sabrina Ahmad Zubaidi. "Knowledge, Attitude and Factors associated with Self-efficacy in Screening and Treatment of Hepatitis C among Primary Care Doctors in Selangor." Malaysian Family Physician 19 (February 20, 2024): 11. http://dx.doi.org/10.51866/oa.454.

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Introduction: Primary care doctors (PCDs) play an increasingly important role in the management of hepatitis C. It is essential for PCDs to have good self-efficacy in screening and treating hepatitis C to achieve good outcomes. This study aimed to determine the knowledge and attitude towards andother factors associated with self-efficacy in screening and treating hepatitis C. Methods: This cross-sectional study was conducted using an online Google Form. PCDs workingat primary healthcare clinics were selected via simple random sampling. The online form contained items on sociodemographic and pr
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Toci, Valentin, and Iraj Hashi. "Law Enforcement Proxies Matter for the Law and Finance Nexus." International Journal of Finance & Banking Studies (2147-4486) 2, no. 3 (2013): 57–75. http://dx.doi.org/10.20525/ijfbs.v2i3.154.

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The paper employs various measures of law enforcement to provide new evidence on the importance of legal institutions for different dimensions of financial development in transition economies. It offers a critical assessment of law enforcement measures employed in recent studies by showing that some proxies for law enforcement in the credit market may not be appropriate. Hence, care should be taken in how the quality of institutions is measured and the context which it represents. An original approach to measuring law enforcement in the credit market is developed by embodying the legal theory
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Atichartakarn, Vichai, Suporn Chuncharunee, Sukit Yamwong та ін. "Relationship Between Pulmonary Artery Pressure and Spleen Volume in Non-Splenectomized Hemoglobin E/β-Thalassemia Patients". Blood 118, № 21 (2011): 2156. http://dx.doi.org/10.1182/blood.v118.21.2156.2156.

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Abstract Abstract 2156 Introduction: Clinically significant pulmonary arterial hypertension (PAH) has been reported in splenectomized hemoglobin E/β-Thalassemia patients. Like primary PAH, the underlying basis is hypercoagulability related thrombotic pulmonary arteriopathy, which results in an increased pulmonary vascular resistance. In the non-splenectomized counterparts with no clear evidence of hypercoagulability only mild PAH is found. To evaluate role of splenomegaly and the accompanying increased blood volume in the pathogenesis of PAH in this group of patients, we studied the relationsh
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Kurmi, Dharmendra, Shekhar Choudhary, and Sandeep Kumar Yadav. "Factors Associated With Avoidance Of Safety Equipment By Construction Workers In Construction Projects." Cuestiones de Fisioterapia 54, no. 1 (2025): 640–44. https://doi.org/10.48047/6bk76z32.

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Safety is a major issue in the construction industry for both unskilled and skilled workers. Accidents occurfrequently every year in the construction industry due to lack of personal protective equipment (PPE) andpoor wearing of the provided PPE. The objective of this paper is to identify the key factors related to"Prevention of Safety Gear by Construction Workers" in construction projects. Questionnaire survey methodwas used for the primary data collection process. As part of the study, 277 samples were collected fromrespondents across various construction sites. SPSS software was used for de
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Aprita Sari, Diyah Ayu, MC Oetami Prasadjaningsih, and MC Oetami Prasadjaningsih. "Millenial Employees Perception Related to Workload, Work Life Balance, Challenge Leadership on Happiness at Work Case Study Kuningan Area South Jakarta." Journal of Accounting and Finance Management 4, no. 2 (2023): 210–19. https://doi.org/10.38035/jafm.v4i2.219.

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The purpose of this study is to analyze the perception millenial employees about workload, work life balance and challange leadership on happiness at work. This study used quantitative data types with the population of this study are employees worked in Kuningan Area South Jakarta. The sample used in this study are 100 respondents. The methode used for data collection is by used a questionnaire distribution technique trough google form. The analysis technique in this study used the inner model andouter model test wich were processed and analyzed using SmartPLS software which is equipped with v
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Bernardoni, Eamon, Rachel M. Frank, Shreya S. Veera, et al. "Biomechanical Analysis of All-Suture Anchor Fixation for Rotator Cuff Repair." Orthopaedic Journal of Sports Medicine 6, no. 7_suppl4 (2018): 2325967118S0017. http://dx.doi.org/10.1177/2325967118s00175.

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Objectives: Suture anchors are commonly utilized during arthroscopic rotator cuff repair (RCR). Recently, all-suture suture-anchor (ASSA) constructs have been introduced for RCR; however, the biomechanical properties of these implants are poorly understood. The purpose of this study was to compare the biomechanical properties of ASSA to conventional suture anchor (CSA) fixation during RCR. Methods: Fourteen fresh-frozen matched pair human cadaveric shoulders (average age 52 ± 13 years) with no documented prior rotator cuff tears or shoulder surgery were dissected. The supraspinatous tendon was
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Kalawar, Rosan Prasad Shah, Pashupati Chaudhary, Raju Rijal, and Bishnu Pokharel. "The Associated Meniscal Tears and Associated Risk Factors in Concomitant ACL Injuries of the Knee: A Retrospective Analysis." Birat Journal of Health Sciences 5, no. 1 (2020): 981–85. http://dx.doi.org/10.3126/bjhs.v5i1.29639.

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Introduction: The pattern of meniscus tear has significant impact onsubsequent rehabilitation and functional outcome as theyare usually associated with ACL injury.Knowledge about associated meniscus tear helps to identifypatients in the early post-traumatic phase. 
 Objectives: To study meniscus tear patterns and associationbetween different tear patterns of meniscus in ACLinjured subjects and to identify potential demographic andother associated risk factors.
 Methodology: Routine arthroscopic findings database of 54 patientsoperated for primary ACL reconstruction from January 2017t
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Adie, John, Wayne Graham, and Marianne Wallis. "Entry Points to the Health System: a review of the emerging community models for management of non-life threatening urgent conditions relevant to Australia." Asia Pacific Journal of Health Management 12, no. 2 (2017): 9–16. http://dx.doi.org/10.24083/apjhm.v12i2.71.

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Problem: The number of presentations to Emergency Departments (EDs) is increasing at levels above population growth rates and these increases are becoming unsustainable.
 Objective: To review evidence for emerging entry points to the health system for patients with non-life threatening urgent conditions (NLTUC) in order to consider more effective healthcare services in Australia.
 Methods: An in-depth review of the Emerald, Medline, CINAHL, Web of Science, Proquest Business and Medical databases from January 2005 to April 2016 matching ‘acute care’ or ‘urgent care’ with general pract
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Azzahra, Elsya Ikhsani. "Tindak Pidana Kekerasan Seksual Inses pada Anak dalam Hukum Positif Indonesia." Journal of Contemporary Law Studies 2, no. 1 (2024): 64–74. http://dx.doi.org/10.47134/lawstudies.v2i1.2128.

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The present study explores the phenomenon of incest, defined as a forbidden marital orrelational alliance wherein individuals engage in matrimonial or sexual relations due toconsanguinity or close familial ties. Incest is categorized within the realm of familial abuseor domestic violence, encapsulating acts wherein individuals coerce or compel their kin intoengaging in sexual activities. The primary objective of this research is to furnish readerswith a comprehensive comprehension of incestuous sexual violence against minors,elucidating the causative factors, typologies, repercussions on child
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Timalsina, Saroj Kumar. "Crony Capitalism in Nepali Politics." Journal of Economic Concerns 15, no. 1 (2024): 56–72. http://dx.doi.org/10.3126/tjec.v15i1.70240.

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The objective of this paper is to examine how crony capitalism undermines Nepali politics. The author of this course drew information from both primary and secondary sources, including key informant interviews, academic works by international authors found online, and social media posts. Since this is a qualitative study, the researcher has interpreted the data gathered while performing the research using descriptive and analytical methodologies. The author of the following article intended to elucidate the basic concept of crony capitalism while also revealing Nepali politics and the impact o
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Rizvi, Sajjad H. "Islam and the Army in Colonial India." American Journal of Islam and Society 27, no. 3 (2010): 122–25. http://dx.doi.org/10.35632/ajis.v27i3.1317.

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After what seems like a strange absence of academic interest, the study ofMuslims in South Asia is catching up – and not all of that interest is motivatedby the contemporary concerns of counter-terrorism and Af-Pak strategy.Part of this intellectual revival has been focused on the Deccan, andone of the best and brightest young historians working in the area is NileGreen, who now teaches at UCLA.The author posits three primary contributions to wider historiographicaldebates. First, it engages the social history of how empire impingedupon communities and practices and often co-opted and promoted
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Koerner, Michael M., Ali Ghodsizad, Uwe Schulz, Aly El Banayosy, Reiner Koerfer, and Gero Tenderich. "Normothermic Ex Vivo Allograft Blood Perfusion in Clinical Heart Transplantation." Heart Surgery Forum 17, no. 3 (2014): 141. http://dx.doi.org/10.1532/hsf98.2014332.

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<p><b>Background:</b> Cold ischemia associated with cold static storage is an independent risk factor for primary allograft failure and survival of patients after orthotopic heart transplantation. The effects of normothermic ex vivo allograft blood perfusion on outcomes after orthotopic heart transplantation compared to cold static storage have been studied.</p><p><b>Methods:</b> In this prospective, nonrandomized, single-institutional clinical study, normothermic ex vivo allograft blood perfusion has been performed using an organ care system (OCS) (Tr
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Swart, Christelle, and Sonja Verwey. "use of technology in relationship management." Communicare: Journal for Communication Studies in Africa 22, no. 1 (2022): 80–99. http://dx.doi.org/10.36615/jcsa.v22i1.1797.

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Technological innovations have changed many aspects of public relations practice, andpublic relations is believed to have entered the “fourth wave” of technological changein the field. To achieve its ultimate objective, namely to build and maintain beneficialrelationships, thus contributing to achieving organisational goals, it is pivotal to explorethe impact of technology on the profession and practice of public relations. Knowledgeof the impact of these innovations will equip public relations with the required knowhow to contribute to the overall objectives of an integrated communication app
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Kaluntas, Tita Natalia, Olly Esry Harryani Laoh, and Yolanda Pinky Ivanna Rori. "EVALUASI PENGELOLAAN DANA DESA DI DESA KALASEY DUA KECAMATAN MANDOLANG KABUPATEN MINAHASA." AGRI-SOSIOEKONOMI 15, no. 1 (2019): 55. http://dx.doi.org/10.35791/agrsosek.15.1.2019.23364.

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This study aims to evaluate Village Fund management in Kalasey Dua illage, Mandolang Sub-district, Minahasa Regency. The study was conducted from May 2018 to January 2019. The data used in this study were primary data and secondary data. Primary data was collected based on interviews with two members of the Village Consultation Board (BPD), three village officials, and 50 community members to find out their responses to Village Fund management. The fifty community members were selected community members that have over the age of 21 years and had lived in the research village for more than 10 y
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Serikova, O. M., V. V. Syvochka, and D. V. Fomenko. "Problems of forming competitive regional innovation systems." Вісник Східноукраїнського національного університету імені Володимира Даля, no. 1 (281) (February 14, 2024): 49–54. http://dx.doi.org/10.33216/1998-7927-2024-281-1-49-54.

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The creation of conditions for the development ofintegrated research, education and business complexeswill be possible through the interaction of political,regulatory, economic, social and cultural factors.Political conditions are determined at the state level. Atthe same time, the integration of education, science andinnovative business has faced some problems, inparticular, related to governance. Therefore, the maintask at present is to ensure real integration in thesesectors in order to ensure innovative transformations notonly in the economy but also in society as a whole, andthe ministry
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Abbas Shah, Tajammal. "COLONIC CANCER." Professional Medical Journal 23, no. 03 (2016): 251–56. http://dx.doi.org/10.29309/tpmj/2016.23.03.1467.

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A prospective study was conducted to see presentation and management of coloniccancer presenting to a surgical unit in a teaching hospital at Faisalabad. Objectives: To knowdifferent presenting symptomatology like abdominal mass, pain, intestinal obstruction, alteredbowel habits, rectal bleeding, age co-relation, sex distribution, anatomic location among coloniccancer patients and management done for these patients. Study Design: A prospective study.Period: February 2009 to March 2010 for one year. Material and Methods: Total 8 patients werediagnosed and treated for colonic cancer presenting i
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Moustaquim, Jasmine, Jasper van Geel, Michel van Kruchten, et al. "Abstract P4-10-01: Testosterone & Tamoxifen (T&T) trial: adding Testosterone to Tamoxifen in male breast cancer patients." Clinical Cancer Research 31, no. 12_Supplement (2025): P4–10–01—P4–10–01. https://doi.org/10.1158/1557-3265.sabcs24-p4-10-01.

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Abstract Background: Male breast cancer (MBC) is very rare and has worse outcome compared to BC in women. MBC specific interventions are lacking. Non-adherence to mainstay tamoxifen treatment is common, due to feminizing side effects and reduced quality of life, and related to worse survival. Thus, well-tolerated endocrine treatment is an unmet need in MBC. MBC expresses both estrogen- and androgen receptors (ER and AR) in 97% of cases. As the AR functions as tumor suppressor in ER+ BC, adding testosterone to tamoxifen may improve both tumor response and tolerability in MBC. Therefore, we asse
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Acevedo, Francisco, Rodrigo Valenzuela, Benjamín Walbaum, et al. "Abstract P4-05-16: FATTY ACID PROFILE ON RED BLOOD CELL MEMBRANE PREDICT BREAST CANCER SUBTYPE." Clinical Cancer Research 31, no. 12_Supplement (2025): P4–05–16—P4–05–16. https://doi.org/10.1158/1557-3265.sabcs24-p4-05-16.

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Abstract Introduction. Metabolic reprogramming is a hallmark of cancer development and progression. Regarding breast cancer (BC) limited evidence assert an association between metabolic changes and its impact on BC biology and subtype. Yet no clear data has evaluated the link between lipid metabolism, measured through red blood-cell membrane (RBCm) composition, and BC subtype determination. Because RBC are the main circulating cells and 90% of its surface is membrane, the fatty acid (FA) measurement on the RBCm seems to be a good marker for FA body status and BC cell relationship with systemic
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Skibińska, Małgorzata, and Dorota Anna Siemieniecka. "Behavioral and socio-emotional disorders as co-occurring factors in the problem of digital device abuse by children and adolescents - a research results." Journal of Modern Science 62, no. 2 (2025): 314–30. https://doi.org/10.13166/jms/207398.

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ObjectivesThe aim of the research was to identify the types of behavioral and emotional disorders as factors that parents (and carers) believe co-occur in the problem of digital device abuse of their children's digital devices.Material and methodsThe study was conducted in 2024. Parents of primary school students in the Kuyavian-Pomeran.voivodship in Poland were included. A questionnaire survey was completed by 1216 persons. The study was quantitative and qualitative.ResultsAnalysis of the data showed that co-occurring factors in the problem of digital device abuse by school children and adole
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Veith, Thomas A., Richard Beck, and Noemi Andor. "Abstract A027: Detecting and modeling frequency-dependent evolution in serially passaged primary triple negative breast cancer patient derived xenografts." Cancer Research 84, no. 3_Supplement_2 (2024): A027. http://dx.doi.org/10.1158/1538-7445.canevol23-a027.

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Abstract Tumor evolution is a contributing factor to most failed cancer treatments. The intratumor heterogeneity of cellular phenotypes found in the tumor microenvironment acts as an evolutionary substate for cancer cells during tumorigenesis, subsequent growth, and after the patient is in the clinic. Selective forces imposed by certain medications can cause the emergence of a tumor with a resistant phenotype. Chemotherapies that target rapidly dividing cells will select for slower dividing ones which are less sensitive to such agents. However, many selective pressures acting on the tumor micr
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Badewy, Rana, Michael Glogauer, Amir Azarpazhooh, et al. "67 Infant Health Status Impacts the Neutrophil Phenotypes and Polyunsaturated Fatty Acids Composition in Human Milk." Paediatrics & Child Health 28, Supplement_1 (2023): e30-e31. http://dx.doi.org/10.1093/pch/pxad055.067.

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Abstract Background The abundance of human milk leukocytes, including neutrophils, changes in response to the health status of mothers and their infants. Elevated leukocyte counts occur during infant infection and return to baseline levels upon recovery. However, it is unclear how infant health status can affect the neutrophil phenotypes and the concentration of fatty acids in their mothers’ human milk. Objectives This study investigates the association between infant health status and human milk neutrophil counts and activation state, and fatty acid levels, in human milk. Design/Methods This
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ÖZSOY, Metin, and Necla TÜLEK. "The impact of COVID-19 pandemic on surveillance of influenza and influenza-like viruses: a single center experience." Journal of Health Sciences and Medicine 6, no. 4 (2023): 756–62. http://dx.doi.org/10.32322/jhsm.1303422.

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Aims: Influenza and the agents responsible for influenza-like illness (ILI) are a significant cause of upper and lower respiratory tract infections, with a notable pattern of seasonal incidence. The surveillance of influenza and agents causing ILI is important for the developmentof a prophylaxis approach and infection control. In the present study, we utilize the Reverse transcription-polymerase chain reaction (RT-PCR) method to identify the presence of influenza virus and other agents associated with ILI in nasopharyngeal smears obtained from patients exhibiting symptoms of influenza and ILI.
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Andor, Noemi. "Abstract 139: Exploiting interactions between ploidy and host physiology." Cancer Research 83, no. 7_Supplement (2023): 139. http://dx.doi.org/10.1158/1538-7445.am2023-139.

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Abstract Whole-genome doubling facilitates rapid tumor evolution and is a hallmark of many cancers, including Glioblastoma (GBM) where it has an incidence of ~14%. GBM remains uniformly lethal, with a median overall survival of 14-16 months, despite aggressive therapy. In people aged 65 and above, prognosis is even more dismal, with median survival of less than 7 months. While comorbidities explain some of the increased age-related risk, age-related changes in the tumor microenvironment likely also contribute. Aging brains have higher incidence of polyploidy (Pearson r=0.80; P=0.031; Nandakuma
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Abdul-Qadir, Abuhamid M. "The Early Development of Islamic Jurisprudence." American Journal of Islam and Society 14, no. 3 (1997): 83–86. http://dx.doi.org/10.35632/ajis.v14i3.2236.

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Professor Ahmed Hasan has made a great contribution to the understandingof the early history of Islamic jurisprudence up to the time of al Shafi'i (d. 204A.H.). A few works. such as The Origins of Muhammadan Jurisprudence byProfessor Joseph Schacht, have been published on the early development ofIslamic jurisprudence. and Hasan's work is a valuable addition. Islamic jurisprudenceis a dynamic, ongoing, and virtually limitless subject. The communitycannot survive without it as long as new issues arise to be resolved andIslamized. Thi field of study helps the community to move forward, encouragin
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Schultz, Andrew R., Saeed Alahmari, Pallavi Singh, et al. "Abstract A013: Integrating imaging and sequencing to compute the subcellular organization of a cell’s transcriptome." Cancer Research 82, no. 10_Supplement (2022): A013. http://dx.doi.org/10.1158/1538-7445.evodyn22-a013.

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Abstract Background: Incorporation of prior information in the form of pathway activity profiles was key in the success of the algorithm that won the DREAM challenge to predict in vitro cell fitness from transcriptomic and other multi-omic datasets (Costello, C. C et al, 2014). We hypothesize that leveraging additional prior information on the spatial distribution of transcriptome activity inside the cell will yield better predictions of cell fitness, which span longer timeframes. Methods: We integrated (i) sequencing and (ii) imaging data obtained from a stomach cancer cell line (NCI-N87). Fo
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Andor, Noemi, Ana Gomes, Gregory Kimmel, et al. "Abstract A030: Characterizing cytotoxic therapy induced shifts in the cost-to-benefit ratio of high ploidy." Cancer Research 82, no. 10_Supplement (2022): A030. http://dx.doi.org/10.1158/1538-7445.evodyn22-a030.

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Abstract Analyses of intra-tumor heterogeneity across multiple cancer types suggest that tumor cell fitness declines once aneuploidy exceeds a certain limit. A significant difference in outcome between tumors above and below the limit however is only evident among therapy-naïve patients, not among patients who subsequently underwent cytotoxic therapy. Our hypothesis is that the context-dependent ambivalence of high ploidy is what accounts for both of these observations. On one hand, high ploidy ameliorates the deleterious effects of missegregation-induced genome-dosage imbalances, on the other
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Tagal, Vural, Jackson Cole, Daria Miroshnychenko, Andriy Marusyk, and Noemi Andor. "Abstract A024: Ploidy as a predictive biomarker for gemcitabine sensitivity in triple-negative breast cancers." Cancer Research 84, no. 3_Supplement_2 (2024): A024. http://dx.doi.org/10.1158/1538-7445.canevol23-a024.

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Abstract The polyploid giant cancer cell (PGCC) state is a common response of cancer cells to various stressors including chemotherapy, irradiation, hypoxia and viral infection. Upon stress, PGCCs adopt an endoreplication in which the genome replicates, mitosis is omitted, and cells grow in size, causing drug resistance. How accessible endoreplication is to a cell, therefore, directly translates to its resistance to therapy. In this study, we hypothesized that endoreplication and PGCC state are more accessible to cancer cells that already have a higher ploidy content prior to therapy. To test
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Nowicka, Zuzanna, Frederika Rentzeperis, Vural Tagal, Konstantin Maksin, Parag Katira, and Noemi Andor. "Abstract 6238: Interactions between ploidy and resource availability shape clonal interference in glioblastoma." Cancer Research 85, no. 8_Supplement_1 (2025): 6238. https://doi.org/10.1158/1538-7445.am2025-6238.

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Whole-genome doubling (WGD) transforms a diploid cell into a tetraploid state, making it prone to genomic instability, aneuploidy, and malignancy. Tumors with evidence of past WGD events range from less than 10% in Non-Hodgkin’s Lymphoma to almost 60% in germ cell cancer. WGD confers advantages, including resistance to stressors, making it a powerful macroevolutionary force. Why, then, isn’t WGD a precursor for most cancers? In Glioblastoma (GBM), ∼86% of tumors lack evidence of WGD in their evolutionary history. We integrated a multi-modal dataset of 11 histopathology whole slide images (WSIs
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Marselino, Frendy, Muh Yusuf, and Sri Redjeki. "Karakteristik Fisik Habitat Peneluran Penyu di Pulau Gelasa, Kepulauan Bangka Belitung." Journal of Marine Research 13, no. 2 (2024): 171–84. http://dx.doi.org/10.14710/jmr.v13i2.39011.

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Penyu merupakan satwa yang termasuk dalam daftar merah satwa yang dilindungi karena populasinya semakin sedikit. Banyaknya perburuan telur,pencemaran alam, hingga perubahan morfodinamika alam mengakibatkan habitat hidupnya menjadi terganggu. Kondisi bentang alam yang kondusif sangat diperlukan untuk meningkatkan populasi penyu, oleh karena itu pengetahuan tentang kondisi fisik habitat yang sesuai untuk peneluran penyu sangat diperlukan. Penelitian ini bertujuan untuk mengetahui karakteristik fisik habitat peneluran penyu di Pulau Gelasa, Kepulauan Bangka Belitung. Karakteristik fisik habitat p
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Greenberg, Charles, Kimberley Youkhana, and Benjamin Djulbegovic. "Combating “Referral Madness Syndrome”in Classical Hematology." Blood 144, Supplement 1 (2024): 3643. https://doi.org/10.1182/blood-2024-212250.

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Background: The Medical University of South Carolina (MUSC) serves a large geographic area. In recent years, MUSC has expanded its network to include hospitals across the state. We recently described the “referral madness syndrome” (Blood Adv (2023) 7 (21):6702-6704) as a major strain on the benign hematology workforce, practitioners, communications, and hospital system operations. There is a significant negative impact of high-volume, fast-paced medical decision-making that can lead to mistakes and poor outcomes. While the root cause of increasing referrals is complex, there is a need to prov
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Tagal, Vural, Jackson P. Cole, Daria Miroshnychenko, Andriy Marusyk, and Noemi Andor. "Abstract LB175: Ploidy as a predictive biomarker for gemcitabine sensitivity in triple-negative breast cancers." Cancer Research 83, no. 8_Supplement (2023): LB175. http://dx.doi.org/10.1158/1538-7445.am2023-lb175.

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Abstract Polyploid giant cancer (PGCC) state is a common response of cancer cells to various stressors including chemotherapy, irradiation, hypoxia and viral infection. Upon stress, PGCCs adopt an endoreplication in which the genome replicates, mitosis is omitted, and cells grow in size, leading to resistance. How accessible endoreplication is to a cell, therefore, directly translates to its resistance to therapy. In this study, we hypothesized that endoreplication and PGCC state are more plausible to cancer cells that already have a higher ploidy content prior to therapy. To test this hypothe
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Ahmad, Waqar. "Islam in a Changing Europe." American Journal of Islam and Society 10, no. 2 (1993): 275–77. http://dx.doi.org/10.35632/ajis.v10i2.2517.

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The conference Islam in a Changing Europe was held amid growingconcern about the future of Islamic and other minority conununities inEurope. The organizers, Hafiz Mirza and David Weir (both at the ManagementCentre), Waqar Ahmad, Charles Husband, and Reg Walker (Departmentof Social and Economic Studies), regarded it as opportune forseveral reasons. First, the Gulf War, the tragic situation in Bosnia, and thecontinuing crises throughout Europe and the Middle East are grim buttimely reminders of the tensions pervading European and Islamic relations,despite strong political, social, and economic t
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Xiao, Lichang. "Basic Principles and Modularity of College English Teaching." Humanistic and Social Seekers, August 30, 2023, 13–17. http://dx.doi.org/10.61206/hass2023080003.

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The “University English Curriculum Teaching Requirements” promulgated by the Ministryof Education in January 2004 is a win-win document that has been democratically discussed manytimes. This article aims to clarify that the new “Teaching Requirements” embodies contemporaryadvanced concepts from philosophy, linguistics, literary criticism, psychology, pedagogy andother disciplines, such as individualization, collaboration, modularization and hypertextualization. It will have a profound impact on my country's college English teaching, English major teachingand English teaching in primary and mid
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Gregory, Vasiliki, Ameesh Isath, Gregg M. Lanier, et al. "Single‐center experience of extended brain‐death donor heart preservation with the organ care system." Artificial Organs, September 6, 2024. http://dx.doi.org/10.1111/aor.14855.

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AbstractBackgroundThe Organ Care System (OCS) (Transmedics, Andover, MA) reduces cold ischemic time of donor hearts by producing a normothermic beating state during ex vivo perfusion, enabling extended ex situ intervals, which potentially increases donor pool. We aimed to compare outcomes in utilization of OCS and conventional cold storage technique.MethodsConsecutive heart transplants following brain death at our institution between May 2022 and July 2023 were analyzed. Recipients were divided into those receiving hearts preserved with OCS [N = 15] and those with conventional cold storage (Co
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Hocum Stone, Laura, Cayla Duffy, Tammy A. Butterick, et al. "Abstract 10277: Effect of CoQ10 on Contractile Reserve of Hibernating Swine Myocardium Following Bypass Surgery." Circulation 132, suppl_3 (2015). http://dx.doi.org/10.1161/circ.132.suppl_3.10277.

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Background: We have previously shown that the recovery of regional function and maximal oxygen consumption in a pig model of hibernating myocardium is incomplete at 4 weeks following bypass surgery (CABG). Because clinical studies suggest a beneficial effect of chronic administration of Coenzyme Q10 (CoQ10) in ischemic heart disease, we tested the benefit of this supplement on contractile reserve, using MRI. Methods: Twelve pigs underwent placement of a constrictor around the LAD artery and had reduced function by MRI at 12 weeks. They then underwent off-pump byass using a left internal mammar
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Dr, Kashyap L. Mokariya. "Impacts of EV Charging on Distribution Grid with Solutions." June 7, 2024. https://doi.org/10.5281/zenodo.13689299.

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Due to the rise in fuel prices, the depletion offossil resources, and environmental concerns, electricalvehicles are a technology that shows the most promise andoffer an alternative to internal combustion engines. Theanalysis of the effects of grid charging for electric vehiclesand its method of mitigation is the primary focus of thispaper. The effects of electrical vehicle grid charging arecomplete in the MATLAB Simulink environment. In order tostabilize the grid against the penetration of electric vehicles, ahybrid control approach is created, with the outer controllerbeing a fuzzy controlle
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Susanto, Aris, Irwandy Tirtawidjaja, Ivan Riyanto Widjaya, and Meyselina Iwan. "Correlation between Completeness of Basic Immunization and Other Factors with the Incidence of Acute Respiratory Infection in Toddlers." Jurnal MedScientiae 2, no. 2 (2023). http://dx.doi.org/10.36452/jmedscientiae.v2i2.3068.

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Acute Respiratory Infection (ARI) is a common disease that occurs in children under five. In developingcountries, the probability of the disease within an age group of toddlers estimated 29% cases perchild/year and in developed countries 5% cases per child / year. It shows that there are 156 millionnew cases per year in the world in which 151 million cases (96.7%) occur in developing countries.Episode cold on Toddlers in Indonesia estimated 2-3 times per year (Rudan et al Bulletin WHO 2008).This study aims to determine the correlation between the comprehensiveness of basic immunization andothe
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Grapsa, Julia, Timothy C. Tan, David Dawson, and Petros Nihoyannopoulos. "Abstract 16108: Right Ventricular Strain is a More Sensitive Marker of Right Ventricular Dysfunction Than Right Ventricular Ejection Fraction in a Cohort of Patients With Idiopathic Pulmonary Arterial Hypertension." Circulation 130, suppl_2 (2014). http://dx.doi.org/10.1161/circ.130.suppl_2.16108.

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Introduction: Strain has been shown to be more sensitive that ejection fraction in detecting subclinical dysfunction in the left ventricle. A number of echocardiographic parameters associated with right heart size and function have been shown to be impaired in idiopathic pulmonary arterial hypertension (IPAH) but there is minimal data on which may be the most sensitive. Aim: To characterize the changes in functional and echocardiographic indices of right ventricular (RV) size and function, in a cohort of IPAH patients followed serially to determine if strain is a more sensitive measure of RV d
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N, Umashree, Tejavathi Nagaraj, Mahalakshmi IP, and Avinash Kumar. "Dental Stem Cells: The Future Of Regenerative Dentistry." RGUHS Journal of Dental Sciences 6, no. 1 (2014). http://dx.doi.org/10.26463/rjds.6_1_7.

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The dawn of this century is brightened by the growing understanding and experimentation with stem cells as primary tools in the expanding regenerative medicine and dentistry. Stem cells are primitive cells that can differentiate and regenerate deteriorating cells in different parts of the body such as heart bones muscles nervous system and tooth. Scientists all over the world have been working on possibilities of using these stem cells to regenerate human cells which are damaged due to illness developmental defects and accidents. The practice of dentistry is likely to be revolutionized by biol
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Hinojar Baydes, R., A. Gonzalez-Gomez, A. Garcia-Martin, et al. "Prognostic value of right ventricular systolic function by speckle tracking echocardiography beyond conventional echocardiography in significant tricuspid regurgitation." European Heart Journal 42, Supplement_1 (2021). http://dx.doi.org/10.1093/eurheartj/ehab724.0117.

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Abstract Background Right ventricular (RV) systolic function is determinant in the evaluation of patients with significant tricuspid regurgitation (TR). Timely detection of RV dysfunction with conventional 2D echocardiography is limited by the geometry and position of the RV. RV strain has emerged as an accurate and sensitive tool for evaluation of RV function with the capability of detect subclinical RV dysfunction Purpose This study was aimed to evaluate the prognostic value of RV strain in consecutive patients with significant TR, in comparison with conventional parameters of RV systolic fu
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