Academic literature on the topic 'Andrew Mousley'

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Journal articles on the topic "Andrew Mousley"

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Scott, Andrew J., Alexandra O'Brien, Weihua Zhou, et al. "Abstract B051: DNA damage signaling activates GTP synthesis to promote glioblastoma treatment resistance." Cancer Research 84, no. 5_Supplement_1 (2024): B051. http://dx.doi.org/10.1158/1538-7445.brain23-b051.

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Abstract Glioblastoma (GBM) is the most common type of invasive brain tumor in adults and is uniformly fatal due to inherent resistance to radiation therapy (RT) and chemotherapy. Our group and others have found that metabolites can regulate DNA repair and therapy resistance in brain tumors, but little is known about how DNA damage regulates metabolic pathway activity in cancer. Here we show that following treatment with RT, GBMs increase rates of de novo guanylate synthesis in vitro and in orthotopic patient-derived xenograft models via signaling through the DNA repair protein DNA-PK. To dete
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Wasko, Urszula N., Jingjing Jiang, Lorenzo Tomassoni, et al. "Abstract B101: Tumor-selective inhibition of active RAS in pancreatic ductal adenocarcinoma." Cancer Research 84, no. 2_Supplement (2024): B101. http://dx.doi.org/10.1158/1538-7445.panca2023-b101.

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Abstract RM-042 is a broad-spectrum inhibitor of the active (GTP-bound) form of KRAS, HRAS, and NRAS, with affinity for both mutant and wild type (WT) variants (RASMULTI(ON)). Given that more than 90% of human pancreatic ductal adenocarcinoma (PDAC) cases are driven by activating mutations in KRAS, we assessed the therapeutic potential of RM-042 in a comprehensive range of PDAC models, including human and murine cell lines, human patient-derived organoids, human PDAC explants, subcutaneous and orthotopic cell-line or patient derived xenografts, syngeneic allografts, and genetically engineered
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Seyfried, Thomas N. "Mouse Brain Development. Andre M. Goffinet , Pasko Rakic." Quarterly Review of Biology 76, no. 2 (2001): 265–66. http://dx.doi.org/10.1086/393966.

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Sánchez-Villagra, Laura A. B. Wilson Carsten Schradin Christian Mitgutsch Fernando C. Galliari Andrea Mess Marcelo R. "Skeletogenesis and sequence heterochrony in rodent evolution, with particular emphasis on the African striped mouse, Rhabdomys pumilio (Mammalia)." Organisms Diversity & Evolution 10, no. 3 (2010): 243–58. https://doi.org/10.1007/s13127-010-0020-4.

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Sánchez-Villagra, Laura A. B. Wilson Carsten Schradin Christian Mitgutsch Fernando C. Galliari Andrea Mess Marcelo R. (2010): Skeletogenesis and sequence heterochrony in rodent evolution, with particular emphasis on the African striped mouse, Rhabdomys pumilio (Mammalia). Organisms Diversity & Evolution (New York, N.Y.) 10 (3): 243-258, DOI: 10.1007/s13127-010-0020-4, URL: http://dx.doi.org/10.1007/s13127-010-0020-4
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Miller, Malcolm. "Jerusalem, Music Centre: Andre Hajdu." Tempo 67, no. 264 (2013): 78. http://dx.doi.org/10.1017/s004029821300017x.

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An 80th birthday concert full of the spirit of youthful exploration reflected the innovative interactive aesthetic of Andre Hajdu, the Hungarian-Israeli composer, whose oeuvre is gradually gaining wider international exposure. Presented by the Jerusalem Music Centre on 29 March 2012, the programme featured works from the last quarter of a century for chamber duo and solo piano, including two premières, culminating in an improvisational interactive jam session by an array of students and colleagues, joined by the composer himself at the piano. To begin was Hajdu's Sonatine for Flute and Cello (
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Riva, Henrique Guimar˜aes, Lina Marcela Henao Montoya, Monica, et al. "Urban biodiversity: Cuterebriasis in free-ranging Robinson's mouse opossum (Marmosa robinsoni) in the suburbs of Barranquilla, Colombia." International Journal for Parasitology: Parasites and Wildlife 21 (August 31, 2023): 83–88. https://doi.org/10.1016/j.ijppaw.2023.02.006.

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Riva, Henrique Guimar˜aes, Montoya, Lina Marcela Henao, Monica, Guti, Franco, errez, Duenas˜Fl, Mariapaz, orez, Olaciregui, Christian, Andrade, Eduardo, Acevedo-Garc, Yuliet Andrea, es, Iv, Soto-Calder, an Darío, on (2023): Urban biodiversity: Cuterebriasis in free-ranging Robinson's mouse opossum (Marmosa robinsoni) in the suburbs of Barranquilla, Colombia. International Journal for Parasitology: Parasites and Wildlife 21: 83-88, DOI: 10.1016/j.ijppaw.2023.02.006, URL: http://dx.doi.org/10.1016/j.ijppaw.2023.02.006
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Soeung, Melinda, Xinmiao Yan, Li Zhang, et al. "Abstract 2702: Hyperprogression due to myeloid mimicry in renal medullary carcinoma treated with nivolumab plus ipilimumab." Cancer Research 84, no. 6_Supplement (2024): 2702. http://dx.doi.org/10.1158/1538-7445.am2024-2702.

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Abstract Renal medullary carcinoma (RMC) is a rare but highly aggressive SMARCB1-deficient kidney cancer that mainly afflicts young individuals of African descent and has few treatment options. Despite the advancements in immune checkpoint therapy (ICT) for other kidney cancers, its efficacy against RMC remains elusive. The majority of RMC patients treated with ICT have experienced aggressively progressive disease as the best response. This hyperprogression was confirmed in our prospective clinical trial of nivolumab plus ipilimumab specifically designed for RMC patients (ClinicalTrials.gov id
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Southard-Smith, Austin N., Reyka G. Jayasinghe, Andre L. Targino da Costa, et al. "Abstract 761: Shared and heterogeneous structural and transcriptional signatures of pre-cancerous cystic lesions in the development of PDAC." Cancer Research 85, no. 8_Supplement_1 (2025): 761. https://doi.org/10.1158/1538-7445.am2025-761.

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Abstract Pancreatic ductal adenocarcinoma PDAC has been observed to arise in the context of diverse pre-cancerous cystic (intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms (MCNs)) and pre-cystic (pancreatic intraepithelial neoplasia (PanIN)) lesions in the clinic. While mouse models of PDAC and these precancerous lesions have existed for a decade, only recently has the transcriptional signature of dysplastic progression for one of these lesions (PanIN) been thoroughly characterized at single cell resolution. Utilizing a multimodal, spatial interrogation via Xenium a
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Xu, Jia, Tiphaine Martin, Daniel Lozano-Ojalvo, et al. "Abstract LB243: Secreted PTEN-long downregulates PI3K signaling and PD-L1 and promotes anti-tumor antigen-presenting cell functions to cause regressions of mouse tumors." Cancer Research 85, no. 8_Supplement_2 (2025): LB243. https://doi.org/10.1158/1538-7445.am2025-lb243.

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Abstract PTEN is well known as a tumor suppressor that inhibits the PI3K/AKT pathway, but the role of its secreted isoform PTEN-Long (PTEN-L) is not fully understood. We developed tools to study PTEN-L independent of PTEN using cancer cell lines engineered to express PTEN-L, a mouse engineered to overexpress Pten-L, and Adeno-Associated Virus (AAV)-Pten-L treated xenograft models. AAV-Pten-L was engineered to be expressed in the liver, where it was efficiently secreted into blood using a strong signal peptide for the liver. Beyond its known ability to inhibit PI3K/AKT signaling, we showed that
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Devkota, Laxman, Rohan Bhavane, Andrew Badachhape, et al. "Abstract 5174: PEGylated liposomal doxorubicin improves oral cancer response to radio-immunotherapy." Cancer Research 83, no. 7_Supplement (2023): 5174. http://dx.doi.org/10.1158/1538-7445.am2023-5174.

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Abstract Introduction: The immunosuppressive tumor microenvironment (TME) in oral cancer inhibits response to conventional treatment (surgery +/- chemoradiotherapy) and check-point inhibitor (αPD1) immunotherapy. The chemotherapeutic agent doxorubicin and its PEGylated liposomal nanoparticle formulation (PLD) have been shown to target myeloid derived suppressor cells (MDSCs) in the TME. In this preclinical work, we investigated whether PLD improves response to radio-immunotherapy in a highly aggressive and immunologically ‘cold’ oral cancer model. Experimental Procedure: Studies were performed
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Dissertations / Theses on the topic "Andrew Mousley"

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Mousser, Jaouad [Verfasser]. "A Large Coverage Verb Lexicon For Arabic / Jaouad Mousser." Konstanz : Bibliothek der Universität Konstanz, 2015. http://d-nb.info/1099956943/34.

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Widner-Andrä, Regina [Verfasser], and Rainer [Akademischer Betreuer] Landgraf. "Assignment of functional impact on genetic data in two mouse models of affective disorders / Regina Andrea Widner-Andrä. Betreuer: Rainer Landgraf." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2012. http://d-nb.info/1023435535/34.

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Jin, Wen [Verfasser], Wolfgang [Akademischer Betreuer] Baumgärtner, Andrea [Akademischer Betreuer] Tipold, and Kirsten [Akademischer Betreuer] Haastert-Talini. "Intraspinal Infection with Theiler’s Murine Encephalomyelitis Virus in Resistant and Susceptible Mouse Strains / Wen Jin ; Wolfgang Baumgärtner, Andrea Tipold, Kirsten Haastert-Talini." Hannover : Stiftung Tierärztliche Hochschule Hannover, 2020. http://d-nb.info/122488292X/34.

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Hipp, Silvia Andrea [Verfasser]. "Influence of different types of amyloid β pathologies on tau pathology in Alzheimer´s disease in different APP-TAU double transgenic mouse models / Silvia Andrea Hipp". Ulm : Universität Ulm, 2018. http://d-nb.info/1166757242/34.

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Forero, Echeverry Andrea [Verfasser], Klaus-Peter [Gutachter] Lesch, Markus [Gutachter] Sauer, and Robert [Gutachter] Blum. "Impact of Cadherin-13 deficiency on the brain serotonin system using mouse models and human iPSC-derived neurons / Andrea Forero Echeverry ; Gutachter: Klaus-Peter Lesch, Markus Sauer, Robert Blum." Würzburg : Universität Würzburg, 2020. http://d-nb.info/1221963287/34.

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Zweck, Jonathan Mark. "This old man." Thesis, 2017. http://hdl.handle.net/2440/112812.

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This Old Man is comprised of a childhood section from a larger novel that interweaves the experiences of a group of childhood friends who, as adults, are compelled to return to their home town to face an evil they were haunted by as children. Due to word count constraints, the chapters submitted for the Thesis are from the ‘childhood section’ of the novel only. The novel in its entirety explores how adult selves are shaped by their past experiences. This first thematic drive is explored alongside another, which focusses on ideas of agency and humanity in the face of these deterministic forces.
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Schwaiger, Andrea [Verfasser]. "Biomedizinische Anwendungen der NMR-MOUSE / vorgelegt von Andrea Schwaiger." 2002. http://d-nb.info/967064333/34.

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Croxford, Andrew Lewis [Verfasser]. "Novel mouse models for use in IL-17A and Th17 research / Andrew Lewis Croxford." 2009. http://d-nb.info/1005380252/34.

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Andre, Philipp [Verfasser]. "Delimitation of the organizer from the posterior notochord : descriptive and functional studies in mouse and African clawed frog / vorgelegt von Philipp Andre." 2009. http://d-nb.info/999426990/34.

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Books on the topic "Andrew Mousley"

1

Andrew Warhol: Micky Mouse (Print Book). Te Neues Pub Group, 1995.

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Crothers, Keith. Adventures of Andrew the Church House Mouse: Andrew's First Adventure. Independently Published, 2018.

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Hipp, Andrew, and Dwight Kuhn. The Life Cycle of a Mouse (Hipp, Andrew. Life Cycles Library.). Rosen Publishing Group, 2002.

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