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Journal articles on the topic 'Andrographis paniculata (Burm. F.) Nees'

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Published: 4 June 2021

Last updated: 9 February 2022

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1

Ghosh, Benoy Kumar, Animesh Kumar Datta, Aninda Mandal, Priyanka Kumari Dubey, and Sandip Halder. "AN OVERVIEW ON ANDROGRAPHIS PANICULATA (BURM. F.) NEES." International Journal of Research in Ayurveda and Pharmacy 3, no. 6 (2012): 752–60. http://dx.doi.org/10.7897/2277-4343.03610.

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Zhang, Xiao-Qi, Guo-Cai Wang, Wen-Cai Ye, Qian Li, Guang-Xiong Zhou, and Xin-Sheng Yao. "New Diterpenoids from Andrographis paniculata (Burm. f.) Nees." Journal of Integrative Plant Biology 48, no. 9 (2006): 1122–25. http://dx.doi.org/10.1111/j.1744-7909.2006.00308.x.

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3

Sudhakaran, MV. "Botanical pharmacognosy of Andrographis paniculata (Burm. F.) Wall. Ex. Nees." Pharmacognosy Journal 4, no. 32 (2012): 1–10. http://dx.doi.org/10.5530/pj.2012.32.1.

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4

Gang, Jian, Hongliang Yuan, Yingxiang Chen, Jun Li, and Rijia Liu. "Use of Andrographis paniculata (Burm. f.) Nees for Treating Hepatitis." Journal of Biobased Materials and Bioenergy 14, no. 5 (2020): 585–600. http://dx.doi.org/10.1166/jbmb.2020.2007.

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Andrographis paniculata (Burm. f.) Nees (APN) is a medicinal plant widely used in Asian countries. APN is used for its anti-inflammatory and antiviral properties. Previous studies did not clarify its pathway to treat hepatitis under the next generation of natural antibiotics. No definite trend has found expression in the multi-component Chinese medicine (MCCM). Besides, the research and development of a particular component in APN can not cover the most pharmacological effects of APN treating hepatitis. Based on the current information biology data, this review found that the intersection numb

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5

Komalasari, Titi, and Sabtanti Harimurti. "A Review of The Anti-diabetic Activity of Andrographis paniculata (Burm. f.) Nees based in-vivo Study." International Journal of Public Health Science (IJPHS) 4, no. 4 (2015): 256. http://dx.doi.org/10.11591/ijphs.v4i4.4743.

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Diabetes mellitus (DM) is ricing nowadays. DM is a metabolic deasease characterized by increasing of glucose blood level for prolonged time. Patient with DM must take medicine for lowering glucose levels in whole life. Synthetic anti-diabetic agent is commonly used and significantly able to maintain the glucose blood levels. However, many side effects will occur during the treatment. Further, people is trying to find an alternative medicine for DM treatment. This paper will discuss about an alternative medicine for anti-diabetic agent that is called <em>Andrographis paniculata</em>

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Komalasari, Titi, and Sabtanti Harimurti. "A Review of The Anti-diabetic Activity of Andrographis paniculata (Burm. f.) Nees based in-vivo Study." International Journal of Public Health Science (IJPHS) 4, no. 4 (2015): 256. http://dx.doi.org/10.11591/.v4i4.4743.

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Diabetes mellitus (DM) is ricing nowadays. DM is a metabolic deasease characterized by increasing of glucose blood level for prolonged time. Patient with DM must take medicine for lowering glucose levels in whole life. Synthetic anti-diabetic agent is commonly used and significantly able to maintain the glucose blood levels. However, many side effects will occur during the treatment. Further, people is trying to find an alternative medicine for DM treatment. This paper will discuss about an alternative medicine for anti-diabetic agent that is called <em>Andrographis paniculata</em>

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7

Nugroho, Agung Endro, Ichwan Ridwan Rais, Iwan Setiawan, et al. "Pancreatic Effect of Andrographolide Isolated from Andrographis paniculata (Burm. F.) Nees." Pakistan Journal of Biological Sciences 17, no. 1 (2013): 22–31. http://dx.doi.org/10.3923/pjbs.2014.22.31.

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8

Li, Ming. "Microbial community in Andrographis paniculata (Burm. f.) Nees in continuous cropping problem." Allelopathy Journal 45, no. 2 (2018): 163–72. http://dx.doi.org/10.26651/allelo.j./2018-45-2-1184.

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Prihatini, R., A. Syarif, A. Bakhtiar, and Mansyurdin. "Leaf epidermis and phytochemical studies of sambiloto (Andrographis paniculata (Burm. F.) Nees)." Journal of Physics: Conference Series 1116 (December 2018): 052050. http://dx.doi.org/10.1088/1742-6596/1116/5/052050.

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10

Ragasa, ConsolacionY, MariaCarmen S. Tan, GlennG Oyong, and Chien-Chang Shen. "Cytotoxic activities of the dichloromethane extracts from Andrographis paniculata (Burm. f.) nees." Journal of Natural Science, Biology and Medicine 9, no. 2 (2018): 201. http://dx.doi.org/10.4103/jnsbm.jnsbm_91_17.

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11

Yang-bo Zheng, Yang, and Ming Li. "Autotoxicity of phenolic acids in root exudates of Andrographis paniculata (Burm. f.) Nees." Allelopathy Journal 45, no. 2 (2018): 153–62. http://dx.doi.org/10.26651/allelo.j./2018-45-2-1183.

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12

Hossain, Sanower, Zannat Urbi, Hidayah Karuniawati, et al. "Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy." Life 11, no. 4 (2021): 348. http://dx.doi.org/10.3390/life11040348.

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Infectious disease (ID) is one of the top-most serious threats to human health globally, further aggravated by antimicrobial resistance and lack of novel immunization options. Andrographis paniculata (Burm. f.) Wall. ex Nees and its metabolites have been long used to treat IDs. Andrographolide, derived from A. paniculata, can inhibit invasive microbes virulence factors and regulate the host immunity. Controlled clinical trials revealed that A. paniculata treatment is safe and efficacious for acute respiratory tract infections like common cold and sinusitis. Hence, A. paniculata, mainly androgr

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13

Widhawati, Riswahyuni, Endang Hanani, and Jamal Zaini. "Andrographis Paniculata (Burm. F.) Nees Induces Clinical and Sputum Conversion in Pulmonary Tuberculosis Patients." Medicine Science | International Medical Journal 4, no. 1 (2015): 1869. http://dx.doi.org/10.5455/medscience.2014.03.8184.

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14

Mishra, Pushpendra Kumar, Rahul Kunwar Singh, Anamika Gupta, et al. "Antibacterial activity of Andrographis paniculata (Burm. f.) Wall ex Nees leaves against clinical pathogens." Journal of Pharmacy Research 7, no. 5 (2013): 459–62. http://dx.doi.org/10.1016/j.jopr.2013.05.009.

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15

Dong, H. J., Z. J. Zhang, J. Yu, Y. Liu, and F. G. Xu. "Chemical Fingerprinting of Andrographis paniculata (Burm. f.) Nees by HPLC and Hierarchical Clustering Analysis." Journal of Chromatographic Science 47, no. 10 (2009): 931–35. http://dx.doi.org/10.1093/chromsci/47.10.931.

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16

Hossain, Md Sanower, Zannat Urbi, Abubakar Sule, and K. M. Hafizur Rahman. "Andrographis paniculata(Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology." Scientific World Journal 2014 (2014): 1–28. http://dx.doi.org/10.1155/2014/274905.

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As aboriginal sources of medications, medicinal plants are used from the ancient times.Andrographis paniculatais one of the highly used potential medicinal plants in the world. This plant is traditionally used for the treatment of common cold, diarrhoea, fever due to several infective cause, jaundice, as a health tonic for the liver and cardiovascular health, and as an antioxidant. It is also used to improve sexual dysfunctions and serve as a contraceptive. All parts of this plant are used to extract the active phytochemicals, but the compositions of phytoconstituents widely differ from one pa

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17

Raina, Archana P., Veena Gupta, N. Sivaraj, and M. Dutta. "Andrographis paniculata (Burm. f.) Wall. ex Nees (kalmegh), a traditional hepatoprotective drug from India." Genetic Resources and Crop Evolution 60, no. 3 (2013): 1181–89. http://dx.doi.org/10.1007/s10722-012-9953-0.

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18

Arpini, Sabrina, Nicola Fuzzati, Andrea Giori, et al. "HPLC-DAD-MS Fingerprint of Andrographis Paniculata (Burn. f.) Nees (Acanthaceae)." Natural Product Communications 3, no. 12 (2008): 1934578X0800301. http://dx.doi.org/10.1177/1934578x0800301208.

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An HPLC-UV fingerprint analysis was developed for the quality evaluation of Andrographis paniculata aerial parts. HPLC-DAD-MS experiments allowed the identification of eleven diterpenes and five flavonoids. Plant material of Indian and Chinese origin was evaluated employing the developed method. The chemical fingerprints of the plant material of different origins do not show significant differences.

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19

Lim, Xin Yi, Janice Sue Wen Chan, Terence Yew Chin Tan, et al. "Andrographis paniculata (Burm. F.) Wall. Ex Nees, Andrographolide, and Andrographolide Analogues as SARS-CoV-2 Antivirals? A Rapid Review." Natural Product Communications 16, no. 5 (2021): 1934578X2110166. http://dx.doi.org/10.1177/1934578x211016610.

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Drug repurposing is commonly employed in the search for potential therapeutic agents. Andrographis paniculata, a medicinal plant commonly used for symptomatic relief of the common cold, and its phytoconstituent andrographolide, have been repeatedly identified as potential antivirals against SARS-CoV-2. In light of new evidence emerging since the onset of the COVID-19 pandemic, this rapid review was conducted to identify and evaluate the current SARS-CoV-2 antiviral evidence for A. paniculata, andrographolide, and andrographolide analogs. A systematic search and screen strategy of electronic da

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20

Rashid, Parisa Tamannur, Muniruddin Ahmed, Md Mizanur Rahaman, and Md Abdul Muhit. "14-Deoxyandrographolide Isolated from Andrographis paniculata (Burm. f) Nees Growing in Bangladesh and its Antimicrobial Properties." Dhaka University Journal of Pharmaceutical Sciences 17, no. 2 (2018): 265–67. http://dx.doi.org/10.3329/dujps.v17i2.39185.

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21

Martin, K. P. "Plant regeneration protocol of medicinally important Andrographis paniculata (Burm. F.) Wallich ex Nees via somatic embryogenesis." In Vitro Cellular & Developmental Biology - Plant 40, no. 2 (2004): 204–9. http://dx.doi.org/10.1079/ivp2003520.

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22

Lattoo, Surrinder K., Rekha S. Dhar, Shabnam Khan, et al. "Comparative analysis of genetic diversity using molecular and morphometric markers in Andrographis paniculata (Burm. f.) Nees." Genetic Resources and Crop Evolution 55, no. 1 (2007): 33–43. http://dx.doi.org/10.1007/s10722-007-9212-y.

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23

Hossain, Md Sanower, Zannat Urbi, and Ing Chia Phang. "Auxin increased adventitious root development in the medicinal plant Andrographis paniculata (Burm. f.) Wall. ex Nees." Agronomy Journal 113, no. 4 (2021): 3222–31. http://dx.doi.org/10.1002/agj2.20745.

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24

Samy, R. Perumal, M. M. Thwin, and P. Gopalakrishnakone. "Phytochemistry, Pharmacology and Clinical Use of Andrographis paniculata." Natural Product Communications 2, no. 5 (2007): 1934578X0700200. http://dx.doi.org/10.1177/1934578x0700200519.

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Andrographis paniculata (Burma f.) Wall ex Nees (Acanthaceae) is a common weed distributed throughout the tropical and subtropical regions. All parts of A. paniculata are extremely bitter in taste. This plant is well known in Siddha, Ayurvedic and traditional (tribal) systems of medicine in India. A. paniculata is used for the treatment of infectious diseases, which account for the major proportion of health problems, and which are most often used in the traditional system of medicine. The major active components of the plant are andrographiloids, which have been extensively studied in a varie

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25

Apriliani, Norviria Tsalasatin, and Tukiran Tukiran. "AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN KEJIBELING (Strobilanthes crispa L., Blume) DAN DAUN SAMBILOTO (Andrographis paniculata Burm. f. Nees) DAN KOMBINASINYA." Jurnal Kimia Riset 6, no. 1 (2021): 68. http://dx.doi.org/10.20473/jkr.v6i1.26634.

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Kejibeling (Strobilanthes crispa L., Blume) dan Sambiloto (Andrographis paniculata Burm. f. Nees) adalah tanaman yang mempunyai kandungan senyawa bioaktif yang memiliki potensi sebagai antioksidan. Penelitian ini memiliki tujuan untuk mengetahui aktivitas antioksidan kombinasi ekstrak etanol daun kejibeling dan daun sambiloto. Pengujian antioksidan sampel menggunakan metode DPPH secara spektrofotometer UV-Vis. Serbuk daun kejibeling dan sambiloto dimaserasi dengan menggunakan pelarut etanol 96% sampai diperoleh ekstrak kental setelah penguapan. Hasil uji aktivitas antioksidan didapatkan nilai

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26

Kumar, Ramesh, Chavlesh Kumar, Ritu Paliwal, et al. "Development of Novel Genomic Simple Sequence Repeat (g-SSR) Markers and Their Validation for Genetic Diversity Analyses in Kalmegh [Andrographis paniculata (Burm. F.) Nees]." Plants 9, no. 12 (2020): 1734. http://dx.doi.org/10.3390/plants9121734.

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Kalmegh (Andrographis paniculata (Burm. F.) Nees) is one of the most important medicinal plants and has been widely explored as traditional medicine. To exploit its natural genetic diversity and initiations of molecular breeding to develop novel cultivars or varieties, developments of genomic resources are essential. Four microsatellite-enriched genomic libraries—(CT)14, (GT)12, (AG)15 and (AAC)8—were constructed using the genomic DNA of A. paniculata. Initially, 183 recombinant colonies were screened for the presence of CT, GT, AG, and AAC microsatellite repeats, out of which 47 clones found

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Singh, Madhulika, Chhaya Yadav, and Farha Bano. "Plant Regeneration from Alginate encapsulated nodes of Andrographis paniculata (Burm. F.) Wallich ex Nees. A Potential Medicinal Herb." Vegetos- An International Journal of Plant Research 31, no. 1 (2018): 28. http://dx.doi.org/10.5958/2229-4473.2018.00004.6.

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Nugroho, AgungEndro, NiKadek Warditiani, Suwidjiyo Pramono, Mohamad Andrie, Eka Siswanto, and Endang Lukitaningsih. "Antidiabetic and antihiperlipidemic effect of Andrographis paniculata (Burm. f.) Nees and andrographolide in high-fructose-fat-fed rats." Indian Journal of Pharmacology 44, no. 3 (2012): 377. http://dx.doi.org/10.4103/0253-7613.96343.

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29

Jiang, Zhi Wen, Ya Nan Wang, Hai Wei Xu, Jing Zhao, Gui Fu Dai, and Hong Min Liu. "Suppression of Novel Andrographolide Derivatives on Murine Splenic T Lymphocyte Proliferation." Advanced Materials Research 393-395 (November 2011): 1000–1003. http://dx.doi.org/10.4028/www.scientific.net/amr.393-395.1000.

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Andrographolide (1) is a primary constituent of Andrographis paniculata (Burm. f.) Nees which is a Chinese herbal medicine possesses extensive pharmacological effects. In this paper, the effect of compound 1 and some 15-alkylidene substituted derivatives of andrographolide (2-13) on murine splenic T lymphocyte proliferation reaction were appraised using MTT assay. The results showed that most of 15-alkylidene substituted andrographolides appraised could exert potent immunosuppressant effects. Especially compound 5, the most potent among all the tested compounds at concentrations with no obviou

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Jayakumar, Thanasekaran, Cheng-Ying Hsieh, Jie-Jen Lee, and Joen-Rong Sheu. "Experimental and Clinical Pharmacology ofAndrographis paniculataand Its Major Bioactive Phytoconstituent Andrographolide." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–16. http://dx.doi.org/10.1155/2013/846740.

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Andrographis paniculata(Burm. F) Nees, generally known as “king of bitters,” is an herbaceous plant in the family Acanthaceae. In China, India, Thailand, and Malaysia, this plant has been widely used for treating sore throat, flu, and upper respiratory tract infections. Andrographolide, a major bioactive chemical constituent of the plant, has shown anticancer potential in various investigations. Andrographolide and its derivatives have anti-inflammatory effects in experimental models asthma, stroke, and arthritis. In recent years, pharmaceutical chemists have synthesized numerous andrographoli

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Xiao, Wen-ping, Wan-ju Zhang, Xu-jie Xiong, and Lan-ying Xu. "Network Pharmacology-based on the Active Components and Molecular Mechanisms of Andrographis paniculata (Burm. f.) Wall. ex Nees in Treating Inflammation." Indian Journal of Pharmaceutical Education and Research 55, no. 3 (2021): 765–73. http://dx.doi.org/10.5530/ijper.55.3.149.

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32

Sajeeb, BK, Uttom Kumar, Shimul Halder, and Sitesh C. Bachar. "Identification and Quantification of Andrographolide from Andrographis paniculata (Burm. f.) Wall. ex Nees by RP-HPLC Method and Standardization of its Market Preparations." Dhaka University Journal of Pharmaceutical Sciences 14, no. 1 (2015): 71–78. http://dx.doi.org/10.3329/dujps.v14i1.23738.

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Andrographis paniculata (Burm. f.) Wall. ex Nees, commonly known as Kalmegh, is widely used as antimalarial drug in herbal and traditional systems. Andrographolide is the major triterpenoid present in the plant and responsible for its therapeutic activities. The identification and quantification of andrographolide were ascertained by various spectrophotometric and chromatographic analyses. The plant sample was extracted with methanol. The amorphous residue obtained from extraction was analyzed for identification of andrographolide by chemical method, TLC, UV-Vis, FT-IR and LCMS/MS analyses. Th

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Thiribhuvanamala, G., S. Parthasarathy, A. Kamalakannan, and K. Rajamani. "Andrographis paniculata (Burn F. Nees) - A new host for root rot pathogen Macrophomina phaseolina Tassi. (Goid)." Medicinal Plants - International Journal of Phytomedicines and Related Industries 12, no. 2 (2020): 318. http://dx.doi.org/10.5958/0975-6892.2020.00041.6.

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Srinath, Mote, Byreddi Bhavani Venkata Bindu, Ayeti Shailaja, and Charu Chandra Giri. "Isolation, characterization and in silico analysis of 3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) gene from Andrographis paniculata (Burm. f) Nees." Molecular Biology Reports 47, no. 1 (2019): 639–54. http://dx.doi.org/10.1007/s11033-019-05172-0.

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35

Worakan, Phapawee, Netiya Karaket, Nuchada Maneejantra, and Kanyaratt Supaibulwatana. "A Phenylurea Cytokinin, CPPU, Elevated Reducing Sugar and Correlated to Andrographolide Contents in Leaves of Andrographis paniculata (Burm. F.) Wall. Ex Nees." Applied Biochemistry and Biotechnology 181, no. 2 (2016): 638–49. http://dx.doi.org/10.1007/s12010-016-2238-x.

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Kshama Dwivedi, Kamini Kumar, and Girjesh Kumar. "Studies on Gamma Rays Induced Cyto-Morphological Variations and Procurement of Some Induced Novel Mutants in Kalmegh [Andrographis paniculata (Burm. f.) Nees]." Cytology and Genetics 55, no. 4 (2021): 379–87. http://dx.doi.org/10.3103/s0095452721040034.

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DJIWANTI, S. RETNO, and SUPRIADI SUPRIADI. "DETERMINASI NEMATODA PARASIT Aphelenchoides sp. PENYEBAB PENYAKIT HAWAR DAUN SAMBILOTO (Andrographis paniculata)." Jurnal Penelitian Tanaman Industri 14, no. 2 (2020): 61. http://dx.doi.org/10.21082/jlittri.v14n2.2008.61-66.

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ABSTRAK<br />Nematoda hawar daun Aphelenchoides sp. telah dilaporkan<br />menyerang dan menyebabkan gugur daun pada sambiloto (Andrographis<br />paniculata (Burm. f.) Wall. ex Nees) (Acanthaceae). Penelitian yang<br />bertujuan untuk mengindentifikasi spesies Aphelenchoides sp. tersebut<br />telah dilakukan di laboratorium, rumah kaca dan kebun percobaan Balai<br />Penelitian Tanaman Obat dan Aromatik pada tahun 2005-2006.<br />Identifikasi dilakukan dengan mengamati gejala khas pada tanaman sakit<br />dan karakteristik morfologi nematoda secara

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Banerjee, Tuhina, Aradhana Singh, Satyanshu Kumar, et al. "Ovicidal and larvicidal effects of extracts from leaves of Andrographis paniculata (Burm. f.) Wall.ex Nees against field isolates of human hookworm (Ancylostoma duodenale)." Journal of Ethnopharmacology 235 (May 2019): 489–500. http://dx.doi.org/10.1016/j.jep.2019.02.021.

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Bindu, B. B. V., Mote Srinath, Aayeti Shailaja, and Charu Chandra Giri. "Proteome analysis and differential expression by JA driven elicitation in Andrographis paniculata (Burm. f.) Wall. ex Nees using Q-TOF–LC–MS/MS." Plant Cell, Tissue and Organ Culture (PCTOC) 140, no. 3 (2019): 489–504. http://dx.doi.org/10.1007/s11240-019-01741-0.

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Cheenickal, Maria, and Dr Romilly Margaret Mendez. "Efficacy of the bioactive compounds of medicinal importance in the leaves of Lantana camara L. and Andrographis paniculata (Burm. f.) Wall. ex Nees." IOSR Journal of Pharmacy and Biological Sciences 12, no. 03 (2017): 33–36. http://dx.doi.org/10.9790/3008-1203073336.

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PITAKBUT, Thanet. "The Antiviral Activity of Andrographolide, the Active Metabolite from Andrographis paniculata (Burm. f.) Wall. ex Nees. against SARS-CoV-2 by Using Bio- and Chemoinformatic Tools." Walailak Journal of Science and Technology (WJST) 17, no. 8 (2020): 851–66. http://dx.doi.org/10.48048/wjst.2020.9728.

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Due to the severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 outbreak, the virus has been wildly spread throughout the world and the number of infected patients has rapidly increased. More importantly, neither the official drug treatment nor the vaccine has been officially offered. These have considerably increased the public concerns internationally and nationally. Recently, there has been one question raised in the Thai society; “Could a common Thai herbal medicine namely Andrographis paniculata be used against SARS-CoV-2 infection?”. It is well-known that the plant has antiviral

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42

Anggraini, Maya Dwi, and Eka Wisnu Kusuma. "UJI EFEK ANTIDIABETES KOMBINASI EKSTRAK HERBA SAMBILOTO (Andrographis paniculata (Burm. F.) Nees.) DAN DAUN SIRSAK (Annona muricata L.) PADA TIKUS JANTAN YANG DIINDUKSI ALOKSAN." Jurnal Ilmiah As-Syifaa 11, no. 1 (2019): 24–29. http://dx.doi.org/10.33096/jifa.v11i1.498.

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Anggraini, Maya Dwi, and Eka Wisnu Kusuma. "UJI EFEK ANTIDIABETES KOMBINASI EKSTRAK HERBA SAMBILOTO (Andrographis paniculata (Burm. F.) Nees.) DAN DAUN SIRSAK (Annona muricata L.) PADA TIKUS JANTAN YANG DIINDUKSI ALOKSAN." Jurnal Ilmiah As-Syifaa 11, no. 1 (2019): 24–29. http://dx.doi.org/10.33096/ja.v11i1.498.

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Yen, Ching-Chi, Yu-Kai Liang, Chao-Pei Cheng, Mei-Chich Hsu, and Yu-Tse Wu. "Oral Bioavailability Enhancement and Anti-Fatigue Assessment of the Andrographolide Loaded Solid Dispersion." International Journal of Molecular Sciences 21, no. 7 (2020): 2506. http://dx.doi.org/10.3390/ijms21072506.

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Andrographolide (AG), a major diterpene lactone isolated from Andrographis paniculata (Burm. f.) Nees (Acanthaceae), possesses a wide spectrum of biological activities. However, its poor water solubility and low bioavailability limit its clinical application. Therefore, this study aimed to develop a solid dispersion (SD) formulation to increase the aqueous solubility and dissolution rate of AG. Different drug-polymer ratios were used to prepare various SDs. The optimized formulation was characterized for differential scanning calorimetry, Fourier transform infrared spectroscopy, and powder X-r

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Wediasari, Febrika, Gumilar A. Nugroho, Zahra Fadhilah, Berna Elya, Heri Setiawan, and Tjandrawati Mozef. "Hypoglycemic Effect of a Combined Andrographis paniculata and Caesalpinia sappan Extract in Streptozocin-Induced Diabetic Rats." Advances in Pharmacological and Pharmaceutical Sciences 2020 (November 10, 2020): 1–9. http://dx.doi.org/10.1155/2020/8856129.

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Introduction. Researchers usually use herbal combinations to explore and develop traditional medicine to obtain additional benefits in the treatment of diseases, including diabetes. This study aims to evaluate the hypoglycemic effect of the combination of Andrographis paniculata (Burm. f.) Wall ex Nees and Caesalpinia sappan Linn extract (APCSE) on diabetes-induced rats. There has not been sufficient research on this combination; however, single extract studies of these plants have been widely conducted. Materials and Methods. Male Sprague Dawley rats (160–200 g) were induced by injecting a lo

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Verma, Kirti, Kushal Pal Singh, Anjali Singh, et al. "Co-cultivation of a medicinal plant kalmegh [Andrographis paniculata (Burm. F.) Wall ex. Nees] with food crops for enhancing field productivity and resource use efficiency." Industrial Crops and Products 159 (January 2021): 113076. http://dx.doi.org/10.1016/j.indcrop.2020.113076.

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Liu, Xuefeng, Yonggang Fan, Jing Xie, Li Zhang, Lihua Li, and Zhenyuan Wang. "Dehydroandrographolide Inhibits Osteosarcoma Cell Growth and Metastasis by Targeting SATB2-mediated EMT." Anti-Cancer Agents in Medicinal Chemistry 19, no. 14 (2019): 1728–36. http://dx.doi.org/10.2174/1871520619666190705121614.

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Background:The 12-hydroxy-14-dehydroandrographolide (DP) is a predominant component of the traditional herbal medicine Andrographis paniculata (Burm. f.) Nees (Acanthaceae). Recent studies have shown that DP exhibits potent anti-cancer effects against oral and colon cancer cells.Objective:This investigation examined the potential effects of DP against osteosarcoma cell.Methods:A cell analyzer was used to measure cell viability. The cell growth and proliferation were performed by Flow cytometry and BrdU incorporation assay. The cell migration and invasion were determined by wound healing and tr

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Smitha, G. R., N. A. Gajbhiye, and Vandana Tripathy. "Influence of drying methods and packaging materials on physico-chemical properties and phytochemical composition of Kalmegh [Andrographis paniculata (Burm. f.) Wall. ex Nees] for shelf life enhancement." Medicinal Plants - International Journal of Phytomedicines and Related Industries 12, no. 2 (2020): 227. http://dx.doi.org/10.5958/0975-6892.2020.00030.1.

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Tiwari, Gunjan, Rakesh Singh, Nivedita Singh, et al. "Study of arbitrarily amplified (RAPD and ISSR) and gene targeted (SCoT and CBDP) markers for genetic diversity and population structure in Kalmegh [Andrographis paniculata (Burm. f.) Nees]." Industrial Crops and Products 86 (August 2016): 1–11. http://dx.doi.org/10.1016/j.indcrop.2016.03.031.

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Liu, Yun-Ta, Haw-Wen Chen, Chong-Kuei Lii, et al. "A Diterpenoid, 14-Deoxy-11, 12-Didehydroandrographolide, in Andrographis paniculata Reduces Steatohepatitis and Liver Injury in Mice Fed a High-Fat and High-Cholesterol Diet." Nutrients 12, no. 2 (2020): 523. http://dx.doi.org/10.3390/nu12020523.

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14-Deoxy-11,12-didehydroandrographolide (deAND), a diterpenoid in Andrographis paniculata (Burm. f.) Nees, acts as a bioactive phytonutrient that can treat many diseases. To investigate the protective effects of deAND on reducing fatty liver disease, male mice were fed a high-fat and high-cholesterol (HFHC) diet without or with 0.05% and 0.1% deAND supplementation. Cholesterol accumulation, antioxidant, and anti-inflammatory activities in liver and liver injury were evaluated after deAND treatment. The results show that deAND treatment for seven weeks reduced plasma alanine aminotransferase ac

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