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Dissertations / Theses on the topic 'Andrographis paniculata'

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1

Xu, Youhong. "Adaptive immune response-modifying and antimicrobial properties of Andrographis paniculata and andrographolide." University of Southern Queensland, Faculty of Sciences, 2009. http://eprints.usq.edu.au/archive/00005134/.

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Andrographis paniculata (AP) is a traditional herbal medicine which is widely used for the treatment of many diseases in Asia. Recently, various biological activities of AP extract or andrographolide (AND), such as immunostimulatory activity, anti-inflammatoryeffect, cytokine induction or deduction, a potential cancer therapeutic agent and T cell activation suppression, have been reported. However the potential ofAP extract or AND to stimulate the specific or adaptive immune response using microbial vaccines has not been determined. In this project, AND has been purifiedfrom AP and its identit
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2

Wongkittipong, Rutchadaporn. "Development of andrographolide extraction process from andrographis paniculata nees in a pulsed column." Toulouse, INPT, 2004. http://www.theses.fr/2004INPT002G.

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Ce travail traite d'extraction solide-liquide à partir de matière végétale. Les caractéristiques (densité, taille des particules, porosité et forme) de l'andrographis paniculata nees, plante traditionnelle de Thai͏̈lande, ont été obtenues. L'extraction de l'andrographolide est étudiée en premier lieu en réacteur Batch. L'influence des conditions de fonctionnement sur la cinétique d'extraction a été étudiée. Des rendements de 70% et 90% ont été atteints pour des temps de 20 et 60 mn respectivement. Un modèle de ransfert de matière basé sur le modèle dit à deux formes est proposé. Un premier ess
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3

Tipakorn, Naiyana. "Effects of Andrographis paniculata (Burm.F.) Nees on performance, mortality and coccidiosis in broiler chickens." Doctoral thesis, [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=964912708.

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4

Mussard, Eugénie. "Andrographis paniculata et ses diterpènes labdanes contre le stress oxydant et l'inflammation dans le vieillissement cutané." Thesis, Orléans, 2019. http://www.theses.fr/2019ORLE3040.

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Avec l'âge et l'exposition à des facteurs environnementaux tels que les rayons solaires, la peau subit une usure naturelle. Elle se caractérise par l’apparition de rides, d’une perte d'élasticité, d’un relâchement et d’un aspect rugueux. Ce projet vise à explorer de nouveaux agents actifs anti-âges issus de la plante Andrographis paniculata (AP). AP est une plante médicinale utilisée en Asie pour traiter les infections respiratoires et diverses maladies inflammatoires. Cette plante est riche en diterpènes labdanes, dont son principal agent bioactif est l’andrographolide. Un extrait méthanoliqu
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5

Pekthong, Dumrongsak. "Evaluation de possibles Interactions Médicamenteuses : Effets d’extraits de Andrographis paniculata sur les enzymes du métabolisme hépatique chez le rat et chez l’Homme." Besançon, 2008. http://www.theses.fr/2008BESA0006.

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6

Chua, Kui Hong, and kuihongchua@hotmail com. "Studies on Andrographis paniculata (Burm. f.) Nees (HDM 15) A Medicinal Native Plant of Brunei Darussalam." RMIT University. Health Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080703.112512.

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Ethno botanical surveys have revealed that Brunei Darussalam has a rich source of tropical medicinal plants. As 80% of the country's land is covered by tropical rainforest, Brunei Darussalam may have some medicinal plants with unique characteristics of secondary metabolites. Some plants such as Catharanthus roseus (L.) G. Don and Eurycoma longifolia Jack have long been used by the local communities to treat various disease conditions. However, no research has been done in terms of the constituents or biological activities of the Brunei Darussalam medicinal plants. We have investigated the gen
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7

Badhe, Pravin. "Characterisation of fractions from Andrographis paniculata and Silybum marianum plant extracts that protect human cells against DNA damage." Thesis, Brunel University, 2016. http://bura.brunel.ac.uk/handle/2438/14796.

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Plants have been utilized as a source of medicines since ancient times. They contain a vast range of secondary metabolites which play important roles in different diseases. The Scope of this study is to define the function of secondary metabolites from Andrographis paniculata (Kalmegh) and Silybum marianum (Milk Thistle) against DNA damage, which initiates many diseases. Sequential extraction of both plant materials was performed with different polarity solvents. Qualitative analysis was performed with Gas (GC) and High Performance Liquid Chromatography (HPLC). Primary extracts screening studi
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8

Chuang, Yalu, and 莊雅如. "Investigation of Effects of Andrographis paniculata." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/80377516070003898914.

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9

Tonarová, Marta. "Analýza extraktu z listů Andrographis paniculata." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-379562.

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1 CHARLES UNIVERSITY IN PRAGUE FACULTY OF PHARMACY IN HRADEC KRÁLOVÉ DEPARTMENT OF PHARMACEUTICAL BOTANY AND ECOLOGY Analysis of Andrographis leaves extract. Marta Tonarová, 2010 Abstract: The analysis of the extract of leaves Andrographis paniculata (Acanthaceae) was accomplished. The commercial ethanol extract with the contents of andrographolides not higher than 10 % represented the tested material. In case of using the standard andrographolide, the thin layer chromatography has proved its very low amount in the extract only, in spite of the fact that studying literature consideres its cont
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10

Yang, Shu-Fang, and 楊淑雱. "Role of Andrographis paniculata Extract in Neuroprotection." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/30755644843011053902.

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碩士<br>中華醫事科技大學<br>生物醫學研究所<br>100<br>Andrographis paniculata Nees., Family Acanthaceae, is a traditional folk medicinal plants, widely used in various applications, and has been used as antiinflammatory, antibacterial, antipyretic and immune promoting traditional therapeutic drugs. Excessive reactive oxygen radicals produced by oxidative stress make the brain hurt easily. It has been known that oxidative stress could easily lead to the generation of neurodegenerative diseases and the extract of Andrographis paniculata is a good antioxidant. Therefore, we used the human neuroblastoma IMR-32 cell
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11

Tseng, Hsiu-Ying, and 曾琇盈. "Antifibrogenic Effects of Andrographis Paniculata in Human Hepatic Stellate Cells." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/65fbqv.

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碩士<br>中華醫事科技大學<br>生物醫學研究所<br>100<br>The hepatic fibrosis is a chronic disease caused by a variety of factors including alcohol abuse, oxidative stress, viral infection, autoimmune diseases, and metabolic diseases. The development of hepatic fibrosis is caused by liver injury, which leads to accumulation of the extracellular matrix proteins (ECM) including type I collagen and fibronectin as well as a-smooth muscle actin (a-SMA) synthesis and deposition, thus forming the fibrous scar. Hepatic stellate cells (HSC) play a key role in the pathogenesis of liver fibrosis. The activation of HSC leads
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12

Lin, Yi-Hsueh, and 林怡紊. "Andrographis paniculata attenuates insulin resistance in HFD-induced skeletal muscle." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/4p7xhe.

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13

SHI, CHUN-ZHAO, and 施春兆. "Studies on the hypotensive and anti-inflammatory effects of andrographis paniculata." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/53365114451016327116.

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14

Tseng, Chih-Chien, and 曾至堅. "Effect of Andrographis paniculata and Lonicera japonica on the remedy of wound." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/45765968505919786813.

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碩士<br>國立東華大學<br>生命科學系<br>100<br>In previous reports indicate that some herbs can be used as wound healing drug. Astragali Radix and Rehmanniae Radix can treat diabetic foot ulcer and promote the wound healing, SBD.4 of Angelica sinensis and madecassoside of Centella asiatica can repair wound. Recently, Andrographis paniculata is used as a traditional medicine for the treatment of respiratory disease, inflammation, hypertension, infectious injury, and snake bites. Some efficacy has been reported including reduced influenza attack rate, promoted vasodilation of lowering blood pressure, anti-clot
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15

Tsai, Han-Ching, and 蔡含卿. "In vivo and in vitro anti-cancer activities of andrographolide derived from Andrographis paniculata." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/44240797237570999099.

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碩士<br>國立成功大學<br>藥理學研究所<br>95<br>Andrographolide (AG) is a bicyclic diterpenoid lactone isolated from the leaves of Andrographis paniculata, an herbal medicine used traditionally as an anti-inflammatory drug for the treatments of laryngitis, diarrhea and rheumatoid arthritis. The present investigation aims at making a systemic study, both in vitro and in vivo, of the anti-cancer cell proliferation, cell cycle arrest, anti-angiogenesis, anti-metastasis and anti-tumor activities of AG. In vitro, AG shows anti-proliferative activity toward a variety of human cancer cell lines. FACS and Western bl
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16

Liu, Yen-ni, and 劉晏妮. "Inhibitory effect of Andrographis paniculata extracts and andrographolide on Epstein-Barr virus lytic cycle." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/07954704385129290225.

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碩士<br>嘉南藥理科技大學<br>生物科技研究所<br>95<br>This investigation examines the aqueous and ethanolic extract from Andrographis paniculata, Rhinacanthus nasutus, Polygonum cuspidatum, Mesona chinensis, Artemisia lactiflora, and Siegesbeckia glabrescens for their anti-Epstein Barr virus (EBV) activities. This work uses a photochemical method to determine the total content of phenolic compounds in the extracts; immunoblotting, inhibition of the expression of EBV immediate-early and early proteins, Rta, Zta and EA-D; the MTT [ 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay] method, cytotox
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17

Huang, Yu-Ju, and 黃鈺如. "Hepatoprotection of Andrographolide and Ethanolic Extract of Andrographis paniculata in Carbon tetrachloride-treated Rats." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/62611338849878374955.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>100<br>Chronic liver diseases and cirrhosis are the eighth leading cause of death in Taiwan. Therefore, prevention and medical therapy of chronic liver diseases is an important public health issue in Taiwan. Andrographis paniculata is a popular Chinese herbal medicine and is reported to display diverse biological activities including hepatoprotection , anti-cancer, and anti-inflammation. The major bioactive compounds of A. paniculata include various flavonoids and terpenoids, and andrographolid (AND), a diterpene lactone, is the most active one. In this study, we i
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18

[Verfasser], Naiyana Tipakorn. "Effects of Andrographis paniculata (Burm.F.) Nees on performance, mortality and coccidiosis in broiler chickens / by Naiyana Tipakorn." 2002. http://d-nb.info/964912708/34.

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19

Kuei-Ting and 張貴婷. "Modulation of the expression of pi class of glutathione S-transferase by Andrographis paniculata extracts and andrographolide." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/06766476164303722718.

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碩士<br>中山醫學大學<br>營養學研究所<br>95<br>Andrographis paniculata (Ap) is a commonly used herb for traditional medicine in many Southeast Asian countries. In the present study, we investigated the effect of Ap on the expression of the pi class of glutathione S-transferase (GSTP) in rat primary hepatocytes. Hepatocytes were treated with 25 or 50 μg/mL of ethanol or ethyl acetate extracts of Ap (ApEE or ApEAE) or 10 or 20 μM andrographolide, which is the major active diterpene lactone of Ap, for 48 h. ApEE, ApEAE, and andrographolide dose-dependently induced GSTP protein and mRNA expression. In a GST act
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20

Wang, Fu-Ming, and 王富銘. "The antihyperlipidemic effect on the combination of ethanol extracts of Andrographis paniculata and Acanthopanax Senticosus in hyperlipidemic hamsters." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/31557358114797322696.

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碩士<br>大仁科技大學<br>製藥科技研究所<br>100<br>The aim of the present study was going to evaluate the plasma lipids lowering effect on the prescription composed of Andrographis paniculata extract and Acanthopanax Senticosus extract at the ratio of 1:3 (APAS). In the present study, the plasma lipid levels were evaluated after hyperlipidemic hamster receiving 8-weeks oral administration with APAS, that was compared with those from LipoCol Forte○R (100 mg/kg/day)-treated group. It has been shown that the plasma lowering activities of APAS (500 mg/kg/day) in TC, TG and LDL-C was approached to 24.34±2.21, 22.94
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21

Liu, Pei-Fen, and 劉珮芬. "Effects of Ethanolic Extract of Andrographis paniculata and Andrographolide on Hepatic Drug-Metabolizing Enzymes and Pharmacokinetics of Tolbutamide in Rats." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/43496326161589574920.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>99<br>Andrographis paniculata has been treated as a medicinal herb in many Asia countries for hundreds of years. Andrographolide, a diterpene lactone, is the most well known active phytochemical in Andrographis paniculata. Andrographis paniculata and andrographolide display many biological activities including anti-diabetes, anti-inflammation, and modulation on drug metabolism. Tolbutamide is an hypoglycemic drug for type II diabetes mellitus patient. cytochrome P450 (CYP) 2C9 is the main CYP isozyme responsible for hydroxylating tolbutamide to hydroxytolbutamide, wh
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Chen, Chih-Min, and 陳志銘. "Effects of Different Nitrogen Fertilizers and Application Rates on the Growth and Physiological-nutrition of Andrographis paniculata and Artemisia indica." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/96951964504900598176.

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碩士<br>國立臺灣大學<br>農業化學研究所<br>92<br>Abstract Various kinds of drug are extract and purtify from plants, therefore, the usage and demand for medicinal plants increase with passing day. One of the methods to obtain high quality medical plants is through cultivation. The objective of this study was to investigate the effects of different kinds and rates of nitrogen fertilizers on the growth and physiological-nutrition of Andrographis paniculata and Artemisia indica Willd. in pot culture. The experiments were conducted in the experiment farm of National Taiwan University. All treatments were replicat
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Low, Mitchell. "A chemical and pharmacological study of a commercial Andrographis paniculata extract and andrographolide, to determine their anti-inflammatory drug potential." Thesis, 2015. http://hdl.handle.net/1959.7/uws:36545.

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There is increasing evidence that chronic inflammation is a contributing factor to many prevalent ageing-related diseases, such as acute and chronic neurodegenerative diseases, degenerative musculoskeletal diseases, cardiovascular diseases, diabetes, and cancer. To date, pharmacotherapy of inflammatory conditions is based mainly on the use of non-steroidal anti-inflammatory drugs (NSAIDs). However, the prolonged use of NSAIDs can cause serious side effects. There is a need to develop novel and safe anti-inflammatory medicines. Andrographis paniculata (Acanthaceae), has been used as an herbal m
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Bisoyi, Harsita. "Elucidation of Anticancer Activity of Andrographis Paniculata and Its Role in the Expression of E-Cadherin and P53 in Prostate Cancer." Thesis, 2015. http://ethesis.nitrkl.ac.in/7352/1/2015_Elucidation__Bisoyi.pdf.

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Plant-derived compounds act as a prevention within the development of many anti-cancer agents. Natural drugs have less toxicity than the commercially available drugs. So now a days they are widely used for curing many diseases including cancer. Among cancer especially prostrate cancer has been responsible for drastic mortality rate in males. Cancer is mainly studied by genetics and epigenetic modification. Mostly drugs are used to restore the function of tumor supressor genes..In our study, we have carried out an effort towards checking the effect of Kalmegh extracts towards restoring the expr
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25

Shi, Chuen-Chao, and 施春兆. "Study on the relaxation effects of the principles of Peganum harmala L and Andrographis paniculata on vascular and tracheal smooth muscles in vitro." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/33790641842170224407.

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博士<br>國立陽明大學<br>藥理學研究所<br>89<br>Following previous studies on the pharmacological effects of Peganum harmala and Andrographis paniculata extracts, the present study mainly examined the in vivo cardiovascular, in vitro vasorelaxant, antiplatelet, and tracheal spasmolytic effects of 4 psychological active principles (harmine, harman, harmaline, and harmalol) from the seeds of Peganum harmala and 3 active principles (deoxyandrographolide, andrographolide, and neoandrographolide) from the leafs of Andrographis paniculata. The following results were obtained in the study on harmala alkal
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Yu-Shiou and 歐俞秀. "Role of PI3K/Akt pathway in up-regulation of Andrographis paniculata extracts- and Andrographolide-induced expression of pi class of glutathione S-transferase in rat primary hepatocytes." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/42986620414653885034.

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碩士<br>中山醫學大學<br>營養學研究所<br>96<br>Andrographis paniculata (Ap) has been widely used as a traditional medicine in Asia for the prevention and treatment of common cold, inflammation, cancer, hyperglycemia and hypertension. Our previous study showed that the ethanol (ApEE) or ethyl acetate (ApEAE) extracts of Ap and andrographolide, the major active diterpene lactone of Ap, induced pi class of glutathione S-transferase (GSTP) expression in rat primary hepatocytes. Also, the induction of GSTP protein expression by Ap extracts and andrographolide was significantly inhibited by wortmannin, an inhibito
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Chern, Huei-Jen, and 陳慧真. "The Constituents fo the Stems of Andrographolis paniculata Nees." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/54929078543293139797.

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28

Cheng, Guo-Wei, and 程國瑋. "Investigation of mechanisms of Andrograpiphis paniculata extract in cellular protection." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/k8pa73.

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碩士<br>中華醫事科技大學<br>生物科技系暨生物醫學研究所<br>104<br>Andrographis paniculata, is a traditional folk medicinal plant, widely used in various applications, such as anti-inflammatory, anti-bacterial, anti-pyretic and immune promoting traditional therapies and has been shown that extract of Andrographis paniculata exerts cytotoxic effects on cancer cells. Several lines of evidence showed that oxidative stress could lead to neurodegenerative diseases. Therefore, we extracted the Andrographis paniculata to study its anti-oxidative abilities and neuroprotective effects using cellular model in neuroblastoma IMR-
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