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Relevant bibliographies by topics / Androstan

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Academic literature on the topic 'Androstan'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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Journal articles on the topic "Androstan"

1

Yildirim, Kudret, Fatih Gulsan, and Ilknur Kupcu. "Biotransformation of testosterone and progesterone by Penicillium digitatum MRC 500787." Collection of Czechoslovak Chemical Communications 75, no. 6 (2010): 675–83. http://dx.doi.org/10.1135/cccc2009550.

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The biotransformation of testosterone and progesterone by Penicillium digitatum MRC 500787 for 5 days is described. The biotransformation of testosterone afforded 5α-androstane-3,17-dione, 3α-hydroxy-5α-androstan-17-one, 3β-hydroxy-5α-androstan-17-one and androst-4-ene-3,17-dione. The biotransformation of progesterone afforded 5α-pregnane-3,20-dione.

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2

Booth, W. D., and C. A. White. "The isolation, purification and some properties of pheromaxein, the pheromonal steroid-binding protein, in porcine submaxillary glands and saliva." Journal of Endocrinology 118, no. 1 (1988): 47—NP. http://dx.doi.org/10.1677/joe.0.1180047.

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ABSTRACT Pheromaxein, the 16-androstene steroid-binding protein with a relative molecular mass of 15 000 was isolated in sub-milligram quantities from the submaxillary gland and saliva of the Gottingen miniature boar, after a fourfold purification involving the following methods: ultrafiltration for submaxillary gland cytosols and ethanol precipitation for saliva, Concanavalin-A-Sepharose affinity chromatography, sodium dodecyl sulphate polyacrylamide gel electrophoresis, 'Extractigel-D' affinity chromatography (to remove sodium dodecyl sulphate) and fast protein-liquid chromatography. Yields

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3

Bhacca, N., and L. Klasinc. "Photoelectron Spectra and Electronic Structure of Some Steroids." Zeitschrift für Naturforschung A 40, no. 7 (1985): 706–8. http://dx.doi.org/10.1515/zna-1985-0709.

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Gas phase Hel photoelectron spectra of 5ɑ-androstane, 5ɑ-androstan-3-one and 5ɑ-androstan- 17-one compared with those of other saturated cyclic hydrocarbons and ketones indicated that the electronic effect of a keto group in steroids is rather local i.e. extending over about two rings.

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4

Pelecanou, M., and S. Nicolaropoulos. "Notizen: On the Synthesis of D-Homoandrostanes." Zeitschrift für Naturforschung B 48, no. 9 (1993): 1305–6. http://dx.doi.org/10.1515/znb-1993-0924.

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The D-ring expansion of 3 β-hydroxy-5 α-androstan-17-one (epiandrosterone) by the cyanogen azide ring-expansion reaction is described. Epiandrosterone was first converted to 17-methylene-3 β-ydroxy-5 α-androstane by a modification of the Wittig reaction employing methylsulfinyl carbanion-dimethyl sulfoxide. Treatment of the 17-methyleno derivative with cyanogen azide followed by hydrolysis led to 3 β-hydroxy-D-homo-5 α-androstan-17 a-one with migrational selectivity.

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Velgová, Helena, and Ladislav Kohout. "6,7-Secoandrostane derivatives." Collection of Czechoslovak Chemical Communications 50, no. 4 (1985): 962–72. http://dx.doi.org/10.1135/cccc19850962.

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6

Kasal, Alexander. "Antiandrogenic A-homo-B,19-dinor-analogues of androgens from 6β-chloro-5-methyl-19-nor-5β-androst-9-enes". Collection of Czechoslovak Chemical Communications 54, № 5 (1989): 1318–26. http://dx.doi.org/10.1135/cccc19891318.

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6β-Chloro derivatives of 5-methyl-19-nor-5β-androst-9-enes (Westphalen diol type) with oxygen functionalities in positions 3 and 17 were converted into diene VI by treatment with lithium aluminium hydride. The lipophilic product of hydrogenation of VI was shown to be 4aα-methyl-A-homo-B,19-dinor-5β,10α-androstane-3β,17β-diol (IX). Various paths leading to dihydrotestosteron analogues, e.g. selective acylation or oxidation of diol IX and partial hydrolysis of diacetate X, have been realized. 17β-Hydroxy-4aα-methyl-A-homo-B,19-dinor-5β,10α-androstan-3-one (XVI) has been found to exhibit antiandr

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7

Crittenden, Christopher M., та Antonio G. DiPasquale. "Two crystallographic forms and the absolute structure of 5α,14α-androstane". Acta Crystallographica Section C Structural Chemistry 77, № 9 (2021): 537–43. http://dx.doi.org/10.1107/s2053229621008408.

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5α,14α-Androstane (C19H32) crystallizes in two different polymorphic forms in the same vapor diffusion experiment. The major form (Form I) crystallizes as thin plates in the space group P21, with Z = 4. These plates are twinned along a long c axis of length 43 Å and readily suffer from radiation damage when diffracted. The minor form (Form II) crystallizes as fine needles in the space group P212121, Z = 3. In the minor form, 5α,14α-androstane cocrystallizes with 5α,14α-androstan-17-one, an oxidation product of 5α,14α-androstane. The presence of 5α,14α-androstan-17-one in the minor form of the

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8

Kohout, Ladislav, and Miroslav Strnad. "Brassinolide analogues without side chain." Collection of Czechoslovak Chemical Communications 54, no. 4 (1989): 1019–27. http://dx.doi.org/10.1135/cccc19891019.

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New brassinolide analogues, characterized by a modified androstane structure without substituent in position 17, were prepared. In the second internode assay, 2α,3α-dihydroxy-B-homo-6-oxa-5α-androstan-7-one (XVII) had the highest brassinoid activity.

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Kohout, Ladislav. "Syntheis of brassino steroids with a five carbon atom ester functionality in position 17." Collection of Czechoslovak Chemical Communications 54, no. 12 (1989): 3348–59. http://dx.doi.org/10.1135/cccc19893348.

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Androstane analogues of brassinolide with a five carbon atom ester functionality in position 17 have been prepared. 2α,3α-Dihydroxy-17β-(3-methylbutyryloxy)-7-oxa-B-homo-5α-androstan-6-one (XVIII) exhibited a suprisingly high brassinolide activity.

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10

Al-Fouti, Khaled, та James R. Hanson. "The Stereochemistry of Osmylation of 2- and 17-Methylene-5α-Androstanes". Journal of Chemical Research 2003, № 4 (2003): 232–33. http://dx.doi.org/10.3184/030823403103173606.

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Osmylation of 2-methylene-5α-androstan-17-one has been shown to afford the 2α-hydroxy-2β-hydroxymethyl derivative whilst 3β-hydroxy-17-methylene-5α-androstane gives the 17α-hydroxy-17β-hydroxymethyl derivative; the facial selectivity of these reactions is discussed.

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Dissertations / Theses on the topic "Androstan"

1

Gabriel, Sven. "Quantenmechanische Berechnung der CD-Spektren von Cyclohexandionderivaten, Lactamen, Ribonuclease A sowie von Androstan-Bisporphyrinen." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=964517450.

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Wieneke, Nadine. "Ursachen und Folgen vermehrter Expression des nukleären Rezeptors Constitutiver-Androstan-Rezeptor (NR1I3) durch Agonisten des nukleären Rezeptors Peroxisomenproliferator-aktivierter-Rezeptor-alpha (NR1C1)." Phd thesis, Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2008/1916/.

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Der Fettsäurestoffwechsel unterliegt vielfältigen Kontrollmechanismen. So wird der Fettsäureabbau über die Induktion und Aktivität spezifischer Enzyme reguliert. Ein zentraler Regulator ist dabei der nukleäre Rezeptor Peroxisomenproliferator-aktivierter-Rezeptor-α (PPARα). PPARα wird durch freie Fettsäuren in der Zelle aktiviert und fördert über die Induktion von Zielgenen den Fettsäuretransport und -abbau sowie die Gluconeogenese und Ketogenese. Der Anstieg an freien Fettsäuren beim Fasten, aber auch im Diabetes aktiviert PPARα. Unabhängig davon wurde in beiden Stoffwechsellagen auch eine erh

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P, Savić Marina. "Sinteza i antiproliferativna aktivnost novih D-homo i D-seko derivata androstana." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2013. http://dx.doi.org/10.2298/NS20130319SAVIC.

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U prvom delu ove doktorske disertacije je izvr&scaron;enasinteza novih derivata androstana sa D-laktonskomfunkcijom ili D-seko derivata, sa modifikacijama u Ai/ili B-prstenovima. U drugom delu je ispitanaantiproliferativna aktivnost odabranihnovosintetizovanih jedinjenja prema humanimtumorskim ćelijskim linijama (MCF-7, MDA-MB-231,PC-3, HeLa, HT-29, K562) kao i prema zdravimćelijama fetalnih fibroblasta pluća (MRC-5).<br>In first part of this work was achieved synthesis of some new androstane derivatives with D-lactone function and new D-seco derivatives with modification in A a

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Jovana, Ajduković. "Sinteza i biološka aktivnost 17-supstituisanih androstanskih derivata." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2013. http://dx.doi.org/10.2298/NS20131008AJDUKOVIC.

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U prvom delu ove doktorske disertacije je izvr&scaron;ena sinteza novih 17α-pikolil i 17(E)-pikoliniliden androstanskih derivata, sa modifikacijama u A- i/ili B-prstenovima. U drugom delu rada je ispitana antiproliferativna aktivnost odabranih novosintetizovanih jedinjenja prema humanim tumorskim  ćelijskim linijama (MCF-7, MDA-MB-231, PC-3, HeLa, HT-29 i A549) kao i prema zdravim ćelijama fetalnih fibroblasta pluća (MRC-5).<br>In the first part of this dissertation, the synthesis of new 17α-picolyl and 17(E)-picolinylidene androstane&nb

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O'Reilly, Jill Marie. "Synthesis and Biochemical Evaluation of a New Series of Aromatase Inhibitors: 7(alpha)-Arylaliphatic Androst-4-ene-3,17-diones and 7(alpha)-Arylaliphatic Androsta-1,4-diene-3,17-diones /." The Ohio State University, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487928649986196.

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6

Maclennan, Richard Alexander. "Activation of constitutive androstane receptor (CAR) in primary human hepatocytes." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/33726/.

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Human populations are at risk of exposure to constitutive androstane receptor (CAR) activators present in a range of substances, including pharmaceuticals, plasticizers and crop protection agents. What exposure to CAR activators means for human health is uncertain. Activation of CAR in rodents is associated with liver hyperplasia, increased proliferation and eventual hepatocarcinoma; however the effect in human hepatic cells is unclear. There are two methods by which a compound can achieve activation of CAR; directly or indirectly via cellular signalling pathways. Phenobarbital is a prototypic

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7

Roy, Jenny. "Synthèse chimique et activité biologique d'agents stéroïdiens pour le traitement du cancer de la prostate et de la leucémie." Thesis, Université Laval, 2006. http://www.theses.ulaval.ca/2006/23962/23962.pdf.

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8

Joseph, Jan Felix [Verfasser]. "Metabolism of androstane derivatives with focus on hydroxylation reactions / Jan Felix Joseph." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1122438877/34.

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9

Gibb, Bruce Clark. "The synthesis and structural examination of 3α,5-cyclo-5α-androstane steroids". Thesis, Robert Gordon University, 1992. http://hdl.handle.net/10059/537.

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The work described in this thesis is based on the synthesis and structural examination of several cyclosteroids. The σ-aromatic steroid 3α,5-cyclo-5α-androstan-6β-ol-17-one was used as a lead compound in an attempt to produce, in particular, the 17α-ethynyl derivative, the 6β-methyl derivative and the 7α-hydroxy, 6β-methyl derivative. Full experimental details of the various routes are provided. X-ray crystallography, along with standard spectroscopic techniques, were utilised in structural determinations. To complement these techniques molecular mechanics were also utilised to predict spectro

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10

Hernandez, Juan Pablo. "Nonylphenol activates the constitutive androstane receptor and causes sexually dimorphic changes in P450 expression." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2008. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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Books on the topic "Androstan"

1

Ahmad, Viqar Uddin, and Anwer Basha, eds. Spectroscopic Data of Steroid Glycosides: Pregnanes, Androstanes, and Miscellaneous. Springer New York, 2006. http://dx.doi.org/10.1007/978-0-387-39578-4.

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Steadman, Robert. The development and clinical application of a simple, non-chromatographic radioimmunoassay for androst-4-ene-3, 17-dione in serum and salvia. University of Birmingham, 1986.

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3

Bain, Sherrie. The Adventures of Abby the Androsian Tabby. CreateSpace Independent Publishing Platform, 2014.

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4

Makin, Hugh L. J. Mass Spectra of Androstanes, Oestrogens and other Steroids (SpecData). Wiley-VCH, 2001.

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Book chapters on the topic "Androstan"

1

Schomburg, Dietmar, and Dörte Stephan. "3alpha-Hydroxy-5beta-androstan-17-one 3alpha-dehydrogenase." In Enzyme Handbook 10. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-57756-7_3.

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2

John, Kaarthik. "Constitutive Androstane Receptor." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_7229-1.

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John, Kaarthik. "Constitutive Androstane Receptor." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-46875-3_7229.

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Schomburg, Dietmar, and Dörte Stephan. "4-Androstene-3,17-dione monooxygenase." In Enzyme Handbook. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-57942-4_163.

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Lynch, Caitlin, Haishan Li, and Hongbing Wang. "Characterization of Constitutive Androstane Receptor (CAR) Activation." In Methods in Pharmacology and Toxicology. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-742-6_11.

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6

Prakash, Surya, and Abhay Bajaj. "Process for Biotransformation of Androsta-4-ene-3, 17-Dione (4-AD) to Androsta-1,4-Diene-3,17-Dione (ADD)." In Microbial Steroids. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7183-1_16.

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Mackowiak, Bryan, and Hongbing Wang. "High-Content Analysis of Constitutive Androstane Receptor Nuclear Translocation." In Methods in Molecular Biology. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9195-2_6.

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8

Winkelmann, Jochen. "Diffusion coefficient of androsta-1,4-diene-3,17-dione in water." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_926.

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Winkelmann, Jochen. "Diffusion coefficient of androsta-1,4-diene-3,17-dione in octan-1-ol." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_925.

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10

Dehnhard, Martin, Hartmut Rohrmann, and Johannes Kauffold. "Measurement of 16-Androstenes (5α-Androst-16-en-3-One, 5α-Androst-16-en-3α-ol, 5α-Androst-16-en-3β-ol) in Saliva of German Landrace and Göttingen Minipig Boars." In Chemical Signals in Vertebrates 12. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5927-9_30.

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Conference papers on the topic "Androstan"

1

LI, Haishan, Guolin SHEN, Wenchao AI, Wenping XIE, Hui HAN, and Huiming CHEN. "Direct activation of Constitutive Androstane Receptor by Phthalates." In International Conference on Biological Engineering and Pharmacy 2016 (BEP 2016). Atlantis Press, 2017. http://dx.doi.org/10.2991/bep-16.2017.77.

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Aoai, Toshiaki, Kenichiro Sato, Kunihiko Kodama, Yasumasa Kawabe, Hajime Nakao, and Morio Yagihara. "Structural design of new alicyclic acrylate polymers with androstane moiety for 193-nm resist." In Microlithography '99, edited by Will Conley. SPIE, 1999. http://dx.doi.org/10.1117/12.350212.

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Li, Hongqi, Qingwei Liu, Jueshu Fang, and Yulong Wang. "Synthesis and Characterization of 3-butyryloxy-16-(a#946;-naphthylmethylene)-5a#945;-androstane-17-one." In International Conference on Biomedical and Biological Engineering. Atlantis Press, 2016. http://dx.doi.org/10.2991/bbe-16.2016.17.

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4

Cherian, Milu T., Apana A. Takwi, Wenwei Lin, and Taosheng Chen. "Abstract C76: A novel small molecule inhibitor of constitutive androstane receptor (CAR) that resensitizes doxorubicin-resistant neuroblastoma cells." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; November 5-9, 2015; Boston, MA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1535-7163.targ-15-c76.

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Reports on the topic "Androstan"

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Agarwal, Rahul. Whole genome resequencing: dissect 5alpha-androst-16-en-3-one region of interest on pigChr13. Cold Spring Harbor Laboratory, 2016. http://dx.doi.org/10.1101/079665.

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