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Journal articles on the topic 'Anesthesia-induced rhabdomyolysis'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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1

Barrons, Robert William, and Liem T. Nguyen. "Succinylcholine-Induced Rhabdomyolysis in Adults: Case Report and Review of the Literature." Journal of Pharmacy Practice 33, no. 1 (2018): 102–7. http://dx.doi.org/10.1177/0897190018795983.

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Purpose: A case of succinylcholine (SCh) and sevoflurane as a probable cause of rhabdomyolysis in an adult is presented, along with a review of the relevant literature and strategies for prevention. Summary: A nondiabetic, morbidly obese 32-year-old female developed rhabdomyolysis after administration of SCh and sevoflurane for diagnostic procedures of 30 minutes’ duration. Thirty-three hours following anesthesia, the patient developed diffuse muscle tenderness and progressive weakness with a creatinine kinase (CK) of 4319 U/L. Urinalysis findings indicated contamination, a white blood cells o
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2

Tang, Thomas T., Herbert W. Oechler, Daniel Siker, Annette D. Segura, and Ralph A. Franciosi. "Anesthesia-induced rhabdomyolysis in infants with unsuspected Duchenne dystrophy." Acta Paediatrica 81, no. 9 (1992): 716–19. http://dx.doi.org/10.1111/j.1651-2227.1992.tb12344.x.

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3

Patel, Anuradha. "Anesthesia-Induced Rhabdomyolysis During Corrective Spine Surgery: A Case Report." British Journal of Medicine and Medical Research 3, no. 4 (2013): 1302–7. http://dx.doi.org/10.9734/bjmmr/2013/3165.

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4

Gray, Rebecca M. "Anesthesia-induced rhabdomyolysis or malignant hyperthermia: is defining the crisis important?" Pediatric Anesthesia 27, no. 5 (2017): 490–93. http://dx.doi.org/10.1111/pan.13130.

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5

Lochhead, K. M., E. D. Kharasch, and R. A. Zager. "Anesthetic effects on the glycerol model of rhabdomyolysis-induced acute renal failure in rats." Journal of the American Society of Nephrology 9, no. 2 (1998): 305–9. http://dx.doi.org/10.1681/asn.v92305.

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Isoflurane, the most widely used inhalational anesthetic, releases inorganic fluoride during its metabolism by the cytochrome P450 system. Recent experimental data indicate that when cultured proximal tubular cells are exposed to inorganic fluoride, they become relatively resistant to myoglobin- and ATP depletion-mediated attack. The present study was undertaken to assess whether isoflurane anesthesia might confer in vivo cytoprotection, possibly by causing renal tubular inorganic fluoride exposure, thereby mitigating a combined myoglobin/ATP depletion model of acute renal failure (glycerol-in
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6

Wappler, Frank, Marko Fiege, Markus Steinfath, et al. "Evidence for Susceptibility to Malignant Hyperthermia in Patients with Exercise-induced Rhabdomyolysis." Anesthesiology 94, no. 1 (2001): 95–100. http://dx.doi.org/10.1097/00000542-200101000-00019.

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Background Malignant hyperthermia (MH), heat stroke, and exercise-induced rhabdomyolysis (ER) were suspected to be related syndromes. However, it is not known whether individuals with history of ER have an increased incidence of susceptibility to MH. To establish an association between ER and susceptibility to MH, the authors determined the MH status in patients with a history of MH-like episodes induced by physical stress. Methods Twelve unrelated patients with ER, 18 patients with anesthesia-induced MH, and 28 controls were investigated with the in vitro contracture test (IVCT) according to
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7

Leo, Anne-Marie, Mark J. McVey, Megumi Iizuka, and Michael D. Richards. "A suspected case of anesthesia-induced rhabdomyolysis in a child undergoing strabismus surgery." Journal of American Association for Pediatric Ophthalmology and Strabismus 23, no. 3 (2019): 167–69. http://dx.doi.org/10.1016/j.jaapos.2019.01.006.

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8

Carsana, Antonella. "Exercise-Induced Rhabdomyolysis and Stress-Induced Malignant Hyperthermia Events, Association with Malignant Hyperthermia Susceptibility, andRYR1Gene Sequence Variations." Scientific World Journal 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/531465.

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Exertional rhabdomyolysis (ER) and stress-induced malignant hyperthermia (MH) events are syndromes that primarily afflict military recruits in basic training and athletes. Events similar to those occurring in ER and in stress-induced MH events are triggered after exposure to anesthetic agents in MH-susceptible (MHS) patients. MH is an autosomal dominant hypermetabolic condition that occurs in genetically predisposed subjects during general anesthesia, induced by commonly used volatile anesthetics and/or the neuromuscular blocking agent succinylcholine. Triggering agents cause an altered intrac
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9

Suzuki, Akiko, Eiji Hashiba, Akinori Matsui, Takeshi Kubota, Hironori Ishihara, and Akitomo Matsuki. "Repeated total intravenous anesthesia for a patient with a history of enflurane-induced rhabdomyolysis." Journal of Anesthesia 11, no. 3 (1997): 231–33. http://dx.doi.org/10.1007/bf02480044.

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10

Timmins, Matthew A., Henry Rosenberg, Marilyn Green Larach, Carly Sterling, Natalia Kraeva, and Sheila Riazi. "Malignant Hyperthermia Testing in Probands without Adverse Anesthetic Reaction." Anesthesiology 123, no. 3 (2015): 548–56. http://dx.doi.org/10.1097/aln.0000000000000732.

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Abstract Background: Malignant hyperthermia (MH) is triggered by reactions to anesthetics. Reports link nonanesthetic-induced MH-like reactions to a variety of disorders. The objective of the authors was to retrospectively investigate the reasons for referrals for MH testing in nonanesthetic cases and assess their phenotype. In addition, the response to the administration of oral dantrolene in nonanesthetic probands with positive caffeine–halothane contracture test (CHCT) was investigated. Methods: Following institutional research ethics board approval, probands without reaction to anesthesia,
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11

Patel, Anuradha, and Sergey Pisklakov. "Anesthesia-Induced Rhabdomyolysis During Corrective Spine Surgery: A Case Report." April 8, 2013. https://doi.org/10.5281/zenodo.7991.

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We present a case in which a pediatric cerebral palsy patient developed intraoperative myoglobinuria and rhabdomyolysis with elevated creatine kinase (CK) during prone scoliosis surgery. A diagnosis of rhabdomyolysis was established with the finding of teacolored urine intraoperatively, and confirmed with elevated urine myoglobin and CK postoperatively. Cerebral palsy patients may develop anesthesia-induced rhabdomyolysis when inhalational anesthetics used.
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12

Irizarry, Tiffany, and Sarah Gradilla. "Case report: Successful treatment of hyperkalemia during general anesthesia in a domestic cat." Frontiers in Veterinary Science 11 (August 8, 2024). http://dx.doi.org/10.3389/fvets.2024.1398128.

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ObjectiveThis study aimed to describe the successful identification and treatment of severe hyperkalemia, cardiac arrhythmia, rhabdomyolysis, and acute kidney injury (AKI) in a domestic cat that underwent general anesthesia for abdominal exploratory surgery. The definitive underlying cause remains unknown; however, a reaction to propofol is suspected.Case summaryA 6-month-old intact male domestic short-hair cat underwent general anesthesia and developed severe intraoperative rhabdomyolysis, hyperkalemia, ventricular fibrillation, and AKI during surgery despite a documented mild hypokalemia and
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13

Bacsik, Julianne. "Preoperative Evaluation of Pediatric Patients with Muscle Disorders." DeckerMed Anesthesiology, January 14, 2019. http://dx.doi.org/10.2310/anes.18004.

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The preoperative assessment of pediatric patients with myopathy begins with a description of which muscle groups are impacted and the degree of disability present. Particular focus on respiratory status is necessary, as weak muscles of respiration can cause ventilatory insufficiency. This is exacerbated by swallowing difficulty, poor clearance of secretions, inadequate cough, and spinal and rib cage deformity. Restrictive lung disease may be severe. Cardiac dysfunction often accompanies skeletal muscle disease. Cardiomyopathy and conduction defects are prevalent in patients with muscle disorde
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14

"Anesthesia Induced Rhabdomyolysis After Lymph Node Biopsy: A Case Report." Archives of Clinical Research and Trials, July 13, 2020, 1–3. http://dx.doi.org/10.36879/acrt.20.000101.

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15

Belitova, Maya, Gergana Georgieva Nikolova, Slavyana Usheva, et al. "Diagnostic Challenges in Malignant Hyperthermia and Anesthesia-Induced Rhabdomyolysis: A Case Study." American Journal of Case Reports 25 (November 5, 2024). http://dx.doi.org/10.12659/ajcr.946306.

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16

Aleman, Monica, Molly McCue, and Rebecca R. Bellone. "Allele Frequencies and Genotypes for the Ryanodine Receptor 1 Variant Causing Malignant Hyperthermia and Fatal Rhabdomyolysis With Hyperthermia in Horses." Journal of Veterinary Internal Medicine 39, no. 3 (2025). https://doi.org/10.1111/jvim.70081.

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ABSTRACTBackgroundFatal anesthesia‐induced malignant hyperthermia (MH) and rhabdomyolysis with hyperthermia documented in Quarter Horses (QH) breeds are caused by a missense variant in the ryanodine receptor 1 gene (RYR1: XP_023505430.1.:p.(R2454G), designated as MH). The reported cases to date have all been heterozygous, and the allele frequency is suspected to be low.ObjectiveTo determine an accurate estimate of MH allele frequency in multiple horse breeds and investigate whether homozygous animals exist in the population.AnimalsIn total, 159 227 horses from 16 breeds who were either submitt
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17

Celik, Enes, Yusuf Ipek, Osman Oguzhan Kursun, Mehmet Nur Talay, and Hakan Akelma. "Anesthesia Management in a Crisponi Syndrome Patient Undergoing Tracheotomy Surgery." Case Reports in Pediatrics 2025, no. 1 (2025). https://doi.org/10.1155/crpe/7470643.

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Increased salivation and contractions of the oropharyngeal muscles are frequently observed in Crisponi syndrome. This causes frequent recurrent lung infections. Anesthesia management can be challenging due to the frequent convulsions that occur during the intubation and extubation of the patient and subsequent cyanosis and hyperthermia attacks. Cold‐induced sweating attacks may also occur due to the low operating room temperature. Hyperthermia attacks can lead to rhabdomyolysis and disseminated intravascular coagulation. Sudden deaths may occur in children with Crisponi syndrome. Hyperthermia,
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18

Suzuki, Akiko, Eiji Hashiba, Akinori Matsui, Takeshi Kubota, Hironori Ishihara, and Akitomo Matsuki. "Repeated total intravenous anesthesia for a patient with a history of enflurane-induced rhabdomyolysis." Journal of Anesthesia 11, no. 3 (1997). http://dx.doi.org/10.1007/s0054070110231.

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19

Yuasa, Haruyuki, Yukio Onoda, Atsuhiro Kitaura, Takashi Mino, Shota Tsukimoto, and Shinichi Nakao. "Anesthesia management in a patient with very long-chain acyl-Coenzyme A dehydrogenase deficiency." JA Clinical Reports 6, no. 1 (2020). http://dx.doi.org/10.1186/s40981-020-00379-8.

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Abstract Background In a patient with very long-chain acyl-Coenzyme A dehydrogenase (VLCAD) deficiency, metabolism of fatty acids is impaired and a supply of alternative energy is limited when glucose level is insufficient on starvation. Case presentation A 37-year-old woman with VLCAD deficiency was diagnosed with an ovarian cyst and was scheduled for laparoscopic ovarian cystectomy. Glucose was administered intravenously with the start of fasting. Anesthesia was induced with remifentanil, midazolam, and thiamylal, maintained with desflurane and remifentanil. Body temperature was maintained a
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20

Ehelepola, N. D. B., R. M. D. C. Ranathunga, A. B. Abeysundara, H. M. R. P. Jayawardana, and P. S. K. Nanayakkara. "Super-refractory status epilepticus, rhabdomyolysis, central hyperthermia and cardiomyopathy attributable to spinal anesthesia: a case report and review of literature." BMC Anesthesiology 24, no. 1 (2024). http://dx.doi.org/10.1186/s12871-024-02485-x.

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Abstract Background There are only six past reports of super-refractory status epilepticus induced by spinal anesthesia. None of those patients have died. Only < 15 mg of bupivacaine was administered to all six of them and to our case. Pathophysiology ensuing such cases remains unclear. Case presentation A 27 year old gravida 2, para 1, mother at 37 weeks of gestation came to the operating theater for an elective cesarean section. She had no significant medical history other than controlled hypothyroidism and one episode of food allergy. Her current pregnancy was uneventful. Her American So
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