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Journal articles on the topic 'Angiomatoid Fibrous Histiocytoma'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Inoue, Yoshihiko, Shiho Terawaki, Kazuko Imamura, et al. "Angiomatoid Fibrous Histiocytoma." Nishi Nihon Hifuka 78, no. 3 (2016): 219–20. http://dx.doi.org/10.2336/nishinihonhifu.78.219.

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2

Sparreboom, E., C. Wetzels, M. Verdijk, S. Mulder, and W. Blokx. "Subcutaneous Angiomatoid Fibrous Histiocytoma Mimicking Metastatic Melanoma." Case Reports in Pathology 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/291623.

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Angiomatoid fibrous histiocytoma is an uncommon soft-tissue tumor of intermediate malignancy that is often misdiagnosed initially. As there is not one immunohistochemical marker that consequently stains positive or negative for angiomatoid fibrous histiocytoma, molecular diagnostics are becoming more widely used. So far three translocations have been reported to arise in angiomatoid fibrous histiocytoma: FUS-ATF1, EWSR1-CREB1, or EWSR1-ATF1. We present a case of angiomatoid fibrous histiocytoma on the upper arm of a 40-year-old female, which was initially misdiagnosed as metastatic melanoma in

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3

Swami, SunilYogiraj, BD Baste, VV Narhire, SS Shashikant, and GF D′Costa. "Angiomatoid fibrous histiocytoma." Indian Journal of Dermatopathology and Diagnostic Dermatology 3, no. 1 (2016): 17. http://dx.doi.org/10.4103/2349-6029.184004.

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4

Makis, William, Anthony Ciarallo, Marc Hickeson, and Vilma Derbekyan. "Angiomatoid Fibrous Histiocytoma." Clinical Nuclear Medicine 36, no. 5 (2011): 376–79. http://dx.doi.org/10.1097/rlu.0b013e31820aa28e.

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5

Ren, Li, Shuang-Ping Guo, Xiao-Ge Zhou, and John K. C. Chan. "Angiomatoid Fibrous Histiocytoma." American Journal of Surgical Pathology 33, no. 10 (2009): 1570–74. http://dx.doi.org/10.1097/pas.0b013e3181b20e64.

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6

Fletcher, Christopher D. M. "Angiomatoid Fibrous Histiocytoma." American Journal of Surgical Pathology 16, no. 4 (1992): 426. http://dx.doi.org/10.1097/00000478-199204000-00012.

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7

Smith, Mark, and Sharon W. Weiss. "Angiomatoid Fibrous Histiocytoma." American Journal of Surgical Pathology 16, no. 4 (1992): 427. http://dx.doi.org/10.1097/00000478-199204000-00013.

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8

Pasricha, Sunil, Garima Durga, Anila Sharma, et al. "Angiomatoid fibrous histiocytoma." Indian Journal of Pathology and Microbiology 65, no. 4 (2022): 921–24. http://dx.doi.org/10.4103/ijpm.ijpm_1468_20.

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Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor of uncertain differentiation with low metastatic potential, most commonly occurring in children, adolescents, and young adults, involving extremities. Due to its rare nature and diverse presentation, both clinically and morphologically, it is often misdiagnosed. It becomes important to correctly diagnose this lesion, given its distinct therapeutic implications. Here, we present the clinical, radiologic, and pathologic findings of two rare cases of AFH. Since AFH is a rare soft tissue tumor with low malignant potential, both pat

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9

Ajlan, Amr M., Karl Sayegh, Tom Powell, et al. "Angiomatoid Fibrous Histiocytoma." Journal of Computer Assisted Tomography 34, no. 5 (2010): 791–94. http://dx.doi.org/10.1097/rct.0b013e3181e39755.

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10

Grossman, Leonard D., Raleigh R. White, and Daniel A. Arber. "Angiomatoid Fibrous Histiocytoma." Annals of Plastic Surgery 36, no. 6 (1996): 649–51. http://dx.doi.org/10.1097/00000637-199606000-00016.

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11

Bajaj, Anubha. "The Vascular Swirls- Angiomatoid Fibrous Histiocytoma." Journal of Clinical and Diagnostic Pathology 1, no. 3 (2021): 15–23. http://dx.doi.org/10.14302/issn.2689-5773.jcdp-20-3648.

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Angiomatoid fibrous histiocytoma (AFH) is an exceptional, soft tissue neoplasm of indeterminate lineage and intermediate malignancy associated with minimal localized tumour reoccurrence and infrequent distant metastasis. Preliminarily contemplated to be a variant or derivative of malignant fibrous histiocytoma or undifferentiated pleomorphic sarcoma or an unusual fibrohistiocytic sarcoma, angiomatoid fibrous histiocytoma predominantly incriminates young po pulation and superficial sites although several extra-somatic sites can be implicated.

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12

Bajaj, Anubha. "The Vascular Swirls- Angiomatoid Fibrous Histiocytoma." Journal of Clinical and Diagnostic Pathology 1, no. 3 (2021): 15–23. http://dx.doi.org/10.14302/issn.2689-5773.jcdp-20-3648.

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Angiomatoid fibrous histiocytoma (AFH) is an exceptional, soft tissue neoplasm of indeterminate lineage and intermediate malignancy associated with minimal localized tumour reoccurrence and infrequent distant metastasis. Preliminarily contemplated to be a variant or derivative of malignant fibrous histiocytoma or undifferentiated pleomorphic sarcoma or an unusual fibrohistiocytic sarcoma, angiomatoid fibrous histiocytoma predominantly incriminates young po pulation and superficial sites although several extra-somatic sites can be implicated.

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13

Costa, Michael J., and Sharon W. Weiss. "Angiomatoid Malignant Fibrous Histiocytoma." American Journal of Surgical Pathology 14, no. 12 (1990): 1126–32. http://dx.doi.org/10.1097/00000478-199012000-00004.

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14

Sood, U., and A. H. Mehregan. "Aneurysmal (angiomatoid) fibrous histiocytoma." Journal of Cutaneous Pathology 12, no. 2 (1985): 157–62. http://dx.doi.org/10.1111/j.1600-0560.1985.tb01617.x.

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15

Wegmann, W., and Ph U. Heitz. "Angiomatoid malignant fibrous histiocytoma." Virchows Archiv A Pathological Anatomy and Histopathology 406, no. 1 (1985): 59–66. http://dx.doi.org/10.1007/bf00710557.

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16

Fukunaga, Masaharu, Takuya Moriya, Yoshio Miyazawa, Shinichiro Ushigome, and Eisei Ishikawa. "Angiomatoid Malignant Fibrous Histiocytoma." International Journal of Surgical Pathology 2, no. 2 (1994): 99–104. http://dx.doi.org/10.1177/106689699400200204.

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17

Talal, Alghamdi Mohammed. "Angiomatoid Fibrous Histiocytoma: Case Report." Egyptian Journal of Hospital Medicine 88, no. 1 (2022): 3423–26. http://dx.doi.org/10.21608/ejhm.2022.248720.

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18

Dunham, Christopher, Jerry Hussong, Michael Seiff, John Pfeifer, and Arie Perry. "Primary Intracerebral Angiomatoid Fibrous Histiocytoma." American Journal of Surgical Pathology 32, no. 3 (2008): 478–84. http://dx.doi.org/10.1097/pas.0b013e3181453451.

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19

Thway, Khin, Andrew G. Nicholson, William A. Wallace, Awatif Al-Nafussi, John Pilling, and Cyril Fisher. "Endobronchial Pulmonary Angiomatoid Fibrous Histiocytoma." American Journal of Surgical Pathology 36, no. 6 (2012): 883–88. http://dx.doi.org/10.1097/pas.0b013e31824b1ee0.

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20

Asakura, Shoji, Noriaki Tezuka, Shuhei Inoue, Naoki Kihara, and Shozo Fujino. "Angiomatoid fibrous histiocytoma in mediastinum." Annals of Thoracic Surgery 72, no. 1 (2001): 283–85. http://dx.doi.org/10.1016/s0003-4975(00)02567-4.

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21

Argenyi, Zsolt B., John J. Van Rybroek, John D. Kemp, and Robert T. Soper. "Congenital Angiomatoid Malignant Fibrous Histiocytoma." American Journal of Dermatopathology 10, no. 1 (1988): 59–67. http://dx.doi.org/10.1097/00000372-198802000-00008.

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22

Morgan, Michael B., Jan Pitha, Sarah Johnson, Bruce Dunn, and Mark Allen Everett. "Angiomatoid Malignant Fibrous Histiocytoma Revisited." American Journal of Dermatopathology 19, no. 3 (1997): 223–27. http://dx.doi.org/10.1097/00000372-199706000-00004.

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23

Munir, Mian Zeeshan, Ethan Bernstein, Roxanne Wadia, and William B. Laskin. "Pulmonary artery angiomatoid fibrous histiocytoma mimicking pulmonary embolism." BMJ Case Reports 16, no. 3 (2023): e252872. http://dx.doi.org/10.1136/bcr-2022-252872.

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A young man presented to the emergency department with pleuritic chest pain and shortness of breath. Of note, he recently went on a long-distance flight of about 9 hours. Given his recent long-distance travel and clinical symptoms, a pulmonary embolism was suspected. However, pathological examination of the excised pulmonary artery intraluminal mass demonstrated an angiomatoid fibrous histiocytoma. This case describes the clinicopathological and immunohistochemical features and molecular profile of a rare type of pulmonary artery tumour, a pulmonary artery angiomatoid fibrous histiocytoma.

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24

Canevari, Margaux, Bryan Keenan, Iren Horkayne-Szakaly, and Markku Miettinen. "A Diagnosis to Wrestle With: Intraventricular Angiomatoid Fibrous Histiocytoma." American Journal of Clinical Pathology 152, Supplement_1 (2019): S63—S64. http://dx.doi.org/10.1093/ajcp/aqz113.065.

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Abstract We report a case of a 15-year-old boy who presented with an intraventricular angiomatoid fibrous histiocytoma. The patient suffered a concussion during a wrestling match and underwent a head and spine CT, which prompted an MRI. MRI revealed an enhancing 2.3-cm mass in the posterior horn of the right lateral ventricle with no hydrocephalus. The patient subsequently admitted to having had headaches with associated appetite suppression but no visual problems or weakness. The tumor was resected. It was composed of sheets and cords of histiocytoid cells with focal pleomorphism. Intersperse

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25

Thway, Khin. "Angiomatoid Fibrous Histiocytoma: A Review With Recent Genetic Findings." Archives of Pathology & Laboratory Medicine 132, no. 2 (2008): 273–77. http://dx.doi.org/10.5858/2008-132-273-afharw.

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Abstract Angiomatoid fibrous histiocytoma is a neoplasm of intermediate biologic potential most often arising in the extremities of children and young adults. Its rarity may lead to misdiagnosis as either a reactive lesion or a benign or higher-grade tumor. Originally described as a type of malignant fibrous histiocytoma, its differentiation remains enigmatic, with precise histogenesis still only hypothesized. Its morphology is distinct, as a circumscribed lesion with sheets of bland spindle to ovoid cells, peripheral lymphoplasmacytic infiltrate, and blood-filled cystic cavities, and half of

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26

Maher, Ossama M., Victor G. Prieto, John Stewart, and Cynthia E. Herzog. "Characterization of Metastatic Angiomatoid Fibrous Histiocytoma." Journal of Pediatric Hematology/Oncology 37, no. 4 (2015): e268-e271. http://dx.doi.org/10.1097/mph.0000000000000313.

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27

Choi, Joon Hyuk, Woo Jung Sung, and Nam Hyuk Lee. "Angiomatoid Fibrous Histiocytoma: A Case Report." Yeungnam University Journal of Medicine 24, no. 2 (2007): 315. http://dx.doi.org/10.12701/yujm.2007.24.2.315.

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28

Cheah, Alison L., Youran Zou, Christopher Lanigan, et al. "ALK Expression in Angiomatoid Fibrous Histiocytoma." American Journal of Surgical Pathology 43, no. 1 (2019): 93–101. http://dx.doi.org/10.1097/pas.0000000000001103.

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29

Van Zwam, Peter, Thomas Mentzel, and Uta Flucke. "ALK Expression in Angiomatoid Fibrous Histiocytoma." American Journal of Surgical Pathology 43, no. 8 (2019): 1156. http://dx.doi.org/10.1097/pas.0000000000001263.

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30

Lai, Eric C. H., Kam Man Chung, Hak Fai Chiu, and Wan Yee Lau. "Angiomatoid fibrous histiocytoma in the neck." ANZ Journal of Surgery 76, no. 6 (2006): 538. http://dx.doi.org/10.1111/j.1445-2197.2006.03769.x.

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31

Hallor, Karolin H., Francesca Micci, Jeanne M. Meis-Kindblom, et al. "Fusion genes in angiomatoid fibrous histiocytoma." Cancer Letters 251, no. 1 (2007): 158–63. http://dx.doi.org/10.1016/j.canlet.2006.11.014.

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32

Naila Jabbar, Farooq Ahmad Rana, Hasham Akram, and Zaka Ullah. "Angiomatoid fibrous histiocytoma; Retroperitoneal rare manifestation." Professional Medical Journal 30, no. 03 (2023): 421–23. http://dx.doi.org/10.29309/tpmj/2023.30.03.7330.

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Angiomatoid fibrous histiocytoma (AFH) is a sporadic, soft tissue cancer with malignant potential that happens most frequently in children and young adults. We represent an infrequent case of young male with retroperitoneal AFH. Only a rare case reports have been defined that classically occur in the extremes of the deep dermis and subcutaneous tissue, followed by head and neck, as well as the trunk. We emphasize that AFH may occur in retroperitoneal tumors. Surgical resection is mainstay management because it decreases the local symptoms.

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33

Nomura, Takashi, Toshiaki Kogame, and Kenji Kabashima. "Analysis of lymphoid tissue markers in angiomatoid fibrous histiocytoma." Journal of Immunology 198, no. 1_Supplement (2017): 60.12. http://dx.doi.org/10.4049/jimmunol.198.supp.60.12.

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Abstract Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue neoplasm of uncertain differentiation. AFH is characterized by nodular distribution of ovoid and spindle cells with blood-filled cystic cavities. It is circumscribed by thick fibrous pseudo-capsule and a surrounding dense lympho-plasmacytic infiltration encompassing germinal centers. In this study, we analyzed the structure of AFH with immunohistochemistry using markers for lymphoid organogenesis. The tumor was a circumscribed pyriform mass, composed of histiocytoid and spindle cells. The top part of the mass encompassed cri

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34

Ohta, Keisuke, Kihachiro Morihisa, Haruhiko Shibata, Eiji Mori, Seiichi Kawamura, and Jun Takita. "Angiomatoid Malignant Fibrous Histiocytoma.: A Case Report." Orthopedics & Traumatology 35, no. 2 (1986): 417–20. http://dx.doi.org/10.5035/nishiseisai.35.417.

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35

HIRAI, Satoko, Junko MORIKAWA, Yoshimasa FUKUI, and Kazuo HARA. "A case of angiomatoid malignant fibrous histiocytoma." Skin Cancer 6, no. 2 (1991): 300–303. http://dx.doi.org/10.5227/skincancer.6.300.

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36

Kim, Chong Jai, Jung Hee Cho, and Je Geun Chi. "Aneurysmal ("angiomatoid") fibrous histiocytoma in a child." Journal of Korean Medical Science 4, no. 4 (1989): 159. http://dx.doi.org/10.3346/jkms.1989.4.4.159.

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37

Seethala, Raja R., and Cesar A. Moran. "Angiomatoid Fibrous Histiocytoma Arising in the Mediastinum." Pathology Case Reviews 11, no. 5 (2006): 222–25. http://dx.doi.org/10.1097/01.pcr.0000244105.26723.19.

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38

Justin Wong, S. B., Aileen Wee, Mark E. Puhaindran, Brendan Pang, and Victor K. M. Lee. "Angiomatoid Fibrous Histiocytoma With Prominent Myxoid Stroma." American Journal of Dermatopathology 37, no. 8 (2015): 623–31. http://dx.doi.org/10.1097/dad.0000000000000263.

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39

Kong, Xiangyi, Dachun Zhao, Guole Lin, Jiaolin Zhou, and Quancai Cui. "Recurrent Painful Perianal Subcutaneous Angiomatoid Fibrous Histiocytoma." Medicine 93, no. 28 (2014): e202. http://dx.doi.org/10.1097/md.0000000000000202.

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40

Martinez, Salutario J., Courtney Coursey Moreno, Emily N. Vinson, Leslie G. Dodd, and Brian E. Brigman. "Angiomatoid fibrous histiocytoma: novel MR imaging findings." Skeletal Radiology 45, no. 5 (2016): 661–70. http://dx.doi.org/10.1007/s00256-016-2344-4.

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41

Rullo, Rosario, Franca Ferraraccio, Rosario Serpico, Francesco Addabbo, Nicoletta Mazzarella, and Vincenzo Maria Festa. "Oral fibrous histiocytoma and its angiomatoid variant." Journal of Cranio-Maxillofacial Surgery 40, no. 5 (2012): 435–38. http://dx.doi.org/10.1016/j.jcms.2011.07.017.

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42

Shah, Diva, Diva Shah, and Leo Cheng. "123. Angiomatoid Fibrous Histiocytoma – A Diagnostic Challenge." British Journal of Oral and Maxillofacial Surgery 60, no. 10 (2022): e52. http://dx.doi.org/10.1016/j.bjoms.2022.11.197.

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43

Thway, Khin, and Cyril Fisher. "Angiomatoid Fibrous Histiocytoma: The Current Status of Pathology and Genetics." Archives of Pathology & Laboratory Medicine 139, no. 5 (2015): 674–82. http://dx.doi.org/10.5858/arpa.2014-0234-ra.

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Context Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue neoplasm of intermediate biologic potential and uncertain differentiation, most often arising in the superficial extremities of children and young adults. While it has characteristic histologic features of nodular distributions of ovoid and spindle cells with blood-filled cystic cavities and a surrounding dense lymphoplasmacytic infiltrate, there is a significant morphologic spectrum, which coupled with its rarity and lack of specific immunoprofile can make diagnosis challenging. Angiomatoid fibrous histiocytoma is associated

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44

Halpern, Alex I., Mohadese Behtaj, Elham Arbzadeh, and Keith D. Mortman. "Primary Pulmonary Myxoid Sarcoma in an Asymptomatic 47-Year-Old Female." Journal of Respiration 4, no. 3 (2024): 158–62. http://dx.doi.org/10.3390/jor4030014.

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Primary pulmonary myxoid sarcoma (PPMS) is a rarely reported, low-grade malignant endobronchial tumor. We describe a case of PPMS in an asymptomatic 47-year-old female. We highlight the clinical and pathologic aspects of PPMS and its relationship with angiomatoid fibrous histiocytoma.

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45

Martelli, Laura, Paola Collini, Cristina Meazza, et al. "Angiomatoid Fibrous Histiocytoma in an HIV-positive Child." Journal of Pediatric Hematology/Oncology 30, no. 3 (2008): 242–44. http://dx.doi.org/10.1097/mph.0b013e318161a9a7.

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46

Chen, Wenfang, Huijuan Shi, Yongdong Liu, Zunfu Ke, and Anjia Han. "Endotracheal angiomatoid ‘malignant’ fibrous histiocytoma: EWSR1 gene rearrangement." Pathology 45, no. 5 (2013): 506–8. http://dx.doi.org/10.1097/pat.0b013e3283634025.

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47

Basu, Sabita, Uma Singhal, and Harsh Mohan. "Fine Needle Aspiration of Angiomatoid Malignant Fibrous Histiocytoma." Acta Cytologica 43, no. 5 (1999): 859–61. http://dx.doi.org/10.1159/000331304.

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48

Petrey, W. Banks, Robin D. LeGallo, Michael G. Fox, and Cree M. Gaskin. "Imaging characteristics of angiomatoid fibrous histiocytoma of bone." Skeletal Radiology 40, no. 2 (2010): 233–37. http://dx.doi.org/10.1007/s00256-010-1023-0.

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49

Al Baccouche, K., and M. Fadia. "A case report: solid-variant angiomatoid fibrous histiocytoma." Pathology 47 (2015): S59. http://dx.doi.org/10.1097/01.pat.0000461469.36312.0f.

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50

Chen, Gang, Andrew L. Folpe, Thomas V. Colby, et al. "Angiomatoid fibrous histiocytoma: unusual sites and unusual morphology." Modern Pathology 24, no. 12 (2011): 1560–70. http://dx.doi.org/10.1038/modpathol.2011.126.

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