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Journal articles on the topic 'Angor'

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Published: 4 June 2021
Last updated: 30 May 2022

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1

Monsuez, J. J. "Angor stable." Archives des Maladies du Coeur et des Vaisseaux - Pratique 2012, no. 213 (December 2012): 46–47. http://dx.doi.org/10.1016/s1261-694x(12)70447-9.

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Benamer, H., and P. G. Steg. "Angor instable. Introduction." Annales de Cardiologie et d'Angéiologie 50, no. 7-8 (November 2001): 357–58. http://dx.doi.org/10.1016/s0003-3928(01)00041-5.

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3

de Castro, R., P. Valdovinos, E. Sanz, and A. Bardají. "Tratamiento médico del angor." Medicine - Programa de Formación Médica Continuada Acreditado 10, no. 36 (June 2009): 2407–15. http://dx.doi.org/10.1016/s0304-5412(09)71444-1.

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Carbonell San Román, A., T. Segura de la Cal, and J. L. Zamorano Gómez. "Tratamiento médico del angor." Medicine - Programa de Formación Médica Continuada Acreditado 11, no. 36 (June 2013): 2198–206. http://dx.doi.org/10.1016/s0304-5412(13)70601-2.

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Carbonell San Román, A., T. Segura de la Cal, and J. L. Zamorano Gómez. "Un caso de angor estable." Medicine - Programa de Formación Médica Continuada Acreditado 11, no. 36 (June 2013): 2231.e1–2231.e3. http://dx.doi.org/10.1016/s0304-5412(13)70607-3.

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6

DENS J. "Laagmoleculaire heparine (LMWH) bij instabiele angor." Tijdschrift voor Geneeskunde 56, no. 11 (January 1, 2000): 862–63. http://dx.doi.org/10.2143/tvg.56.11.5000770.

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Ben Abdelghani, K., M. Mahfoudhi, L. Baili, S. Turki, C. H. Ben Taarit, and A. Kheder. "Angor mésentérique révélant une endocardite infectieuse." La Revue de Médecine Interne 27 (December 2006): S393. http://dx.doi.org/10.1016/j.revmed.2006.10.258.

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Dacosta, A., J. M. Guy, M. Thu Thao, A. Cerisier, M. Lamaud, L. Denis, R. Gonthier, and H. Verneyre. "Angor à coronaires saines et sclérodermie." La Revue de Médecine Interne 14, no. 8 (January 1993): 804–5. http://dx.doi.org/10.1016/s0248-8663(05)81429-8.

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9

Halna du Fretay, X., B. Blanchard-Lemoine, B. Schnebert, and J. Viossat. "Angor spastique : quel regard en 2011 ?" Annales de Cardiologie et d'Angéiologie 60, no. 6 (December 2011): 317–23. http://dx.doi.org/10.1016/j.ancard.2011.09.002.

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10

Benamer, Hakim, and Vincent Millien. "Angor spastique : un défi diagnostique et thérapeutique." La Presse Médicale 47, no. 9 (September 2018): 798–803. http://dx.doi.org/10.1016/j.lpm.2018.08.004.

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11

Toujani, S., I. Ben Ghorbel, T. Ben Salem, M. Chihaoui, A. Hamzaoui, F. Said, M. Khanfir, M. Lamloum, and H. Houman. "Angor mésentérique révélant une maladie de Takayasu." La Revue de Médecine Interne 36 (December 2015): A160. http://dx.doi.org/10.1016/j.revmed.2015.10.131.

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12

Valdovinos, P., R. de Castro, L. Krsticevic, and A. Bardají. "Manejo general y extrahospitalario del paciente con angor." Medicine - Programa de Formación Médica Continuada Acreditado 10, no. 36 (June 2009): 2430–38. http://dx.doi.org/10.1016/s0304-5412(09)71447-7.

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13

Carbonell San Román, A., T. Segura de la Cal, and J. L. Zamorano Gómez. "Protocolo de tratamiento en el angor estable crónico." Medicine - Programa de Formación Médica Continuada Acreditado 11, no. 36 (June 2013): 2222–26. http://dx.doi.org/10.1016/s0304-5412(13)70605-x.

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14

Methani, K., G. Durand de Gevigney, J. P. Jourdes, and G. Fournier. "Angor paradoxal et infarctus du myocarde après nifédipine." La Revue de Médecine Interne 8, no. 4 (September 1987): 446–47. http://dx.doi.org/10.1016/s0248-8663(87)80025-5.

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15

Cabrera, S., I. Serrano, J. Sans, and A. Bardají. "Protocolo de tratamiento farmacológico en el angor estable crónico." Medicine - Programa de Formación Médica Continuada Acreditado 10, no. 36 (June 2009): 2449–51. http://dx.doi.org/10.1016/s0304-5412(09)71451-9.

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Sans, J., I. Serrano, S. Cabrera, and A. Bardají. "Protocolo de tratamiento revascularizador en el angor estable crónico." Medicine - Programa de Formación Médica Continuada Acreditado 10, no. 36 (June 2009): 2452–53. http://dx.doi.org/10.1016/s0304-5412(09)71452-0.

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17

Martínez Posada, Patricia, Francisco Mula Falcón, and María José Romero-Reyes. "Angor and heart failure as first manifestation of lymphoma." Medicina Clínica (English Edition) 151, no. 3 (August 2018): e13-e14. http://dx.doi.org/10.1016/j.medcle.2018.05.038.

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18

Martínez Posada, Patricia, Francisco Mula Falcón, and María José Romero-Reyes. "Angor e insuficiencia cardiaca como primera manifestación de linfoma." Medicina Clínica 151, no. 3 (August 2018): e13-e14. http://dx.doi.org/10.1016/j.medcli.2017.12.017.

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19

Drobinski, G. "Angor estable e inestable: fisiopatología, diagnóstico y modalidades terapéuticas." EMC - Tratado de Medicina 1-3 (January 1999): 1–8. http://dx.doi.org/10.1016/s1636-5410(99)70025-5.

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20

Blasco, Pedro Betrián, Josep Girona Comas, Marcos Murtra Ferre, and Ricard del Alcazar Muñoz. "Angor in a child: Left main coronary artery atresia." International Journal of Cardiology 108, no. 1 (March 2006): 109–10. http://dx.doi.org/10.1016/j.ijcard.2005.01.062.

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21

Bayoumeu, F., M. Aallali, A. Koebele, G. Steschenko, and M. C. Laxenaire. "Angor et sulprostone au cours d’une hémorragie de la délivrance." Annales Françaises d'Anesthésie et de Réanimation 21, no. 8 (October 2002): 668–71. http://dx.doi.org/10.1016/s0750-7658(02)00696-2.

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22

Danchin, N. "Angor instable et infarctus. Les principaux résultats des derniers mois." Annales de Cardiologie et d'Angéiologie 51, no. 1 (January 2002): 44–47. http://dx.doi.org/10.1016/s0003-3928(01)00063-4.

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23

D’Negri, Carlos E., Liliana Marelich, Daniel Vigo, Rafael S. Acunzo, Luis A. Girotti, Daniel P. Cardinali, and Leonardo Nicola Siri. "Circadian periodicity of heart rate variability in hospitalized angor patients." Clinical Autonomic Research 15, no. 3 (June 2005): 223–32. http://dx.doi.org/10.1007/s10286-005-0280-9.

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24

Halna du Fretay, X., D. Mohammed Saeed, and H. Benamer. "Mort subite et angor spastique : quelle stratégie diagnostique et thérapeutique ?" Annales de Cardiologie et d'Angéiologie 63, no. 6 (December 2014): 465–70. http://dx.doi.org/10.1016/j.ancard.2014.09.036.

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25

Conri, P., P. Legendre, J. C. Baste, D. Barcat, and C. Conri. "Angor intestinal et maladie de Horton : Artérite inflammatoire de l'artère mésentérique." La Revue de Médecine Interne 23 (December 2002): 620s. http://dx.doi.org/10.1016/s0248-8663(02)80534-3.

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26

Pârvu, Irina, Andreea Șerban, Adrian Mereuţă, Tiberiu Nanea, and Adriana Ilieșiu. "A Subtle Electrocardiographic Clue for a Major Problem." Internal Medicine 16, no. 4 (August 1, 2019): 57–63. http://dx.doi.org/10.2478/inmed-2019-0077.

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AbstractAcute coronary syndromes exhibit rapid and variable ischemic dynamics, with consecutive electrocardiographic changes, sometimes in the absence of angina.We report the case of a 50 year-old man, admitted for suspected angor de novo, asymptomatic upon admission, and with a normal electrocardiogram. After a few hours, the repeated electrocardiogram displays biphasic T waves in V2–V4, in the absence of symptoms, and then marked ST elevation in the same territory, without chest pain. The patient is transferred with a STEMI diagnosis, and the coronary angiography documents a critical sub-occlusive stenosis in the proximal segment of the left anterior descending artery (LAD), for which a drug-eluting stent is inserted, with a favourable evolution.Wellens syndrome is defined by characteristic electrocardiographic changes of T waves in leads V2–V4, occurring in the context of unstable angina, usually without pain. They express a critical stenosis in the proximal LAD artery. Recognition of the Wellens syndrome is crucial, as these “pre-infarction” changes tend to evolve, sometimes rapidly, to an extensive anterior myocardial infarction. The rapid and unpredictable ischemic electrocardiographic changes make this case remarkable, as they occur in an asymptomatic patient with unstable angina (angor de novo), thus underlining the need for careful supervision in such patients.
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27

Saeed, Hatem, Dinia Mohamed, Nadia Bourzine, El Boussaadani Badre, J. Zarzur, and M. Cherti. "Spastic Angor Revealed by Acute Coronary Syndrome: A Case Report with Literature Review." Scholars Journal of Applied Medical Sciences 08, no. 02 (February 20, 2020): 630–32. http://dx.doi.org/10.36347/sjams.2020.v08i02.048.

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28

Ducloux, G., G. Vaksmann, J. Manouvrier, and C. Caron. "L'« angor œsophagien: dépistage par manométrie œsophagienne avec test au maléate de méthylergométrine." La Revue de Médecine Interne 8, no. 1 (January 1987): 13–20. http://dx.doi.org/10.1016/s0248-8663(87)80102-9.

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29

Halna du Fretay, X., B. Schnebert, O. Genée, and M. Boyo. "Quel patient âgé, ayant un angor stable, doit être adressé en chirurgie cardiaque ?" Annales de Cardiologie et d'Angéiologie 67, no. 6 (December 2018): 429–38. http://dx.doi.org/10.1016/j.ancard.2018.09.018.

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30

Johnson, Norman F. "REVISION OF WORLD SPECIES OF PARATELENOMUS DODD (HYMENOPTERA: SCELIONIDAE)." Canadian Entomologist 128, no. 2 (April 1996): 273–91. http://dx.doi.org/10.4039/ent128273-2.

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AbstractThe genus Paratelenomus Dodd is revised from a worldwide perspective. Three species are described as new: P. angor [Taiwan, Thailand], P. indivisus [Papua New Guinea, Australia], and P. matinalis [Vanuatu]. Paratelenomus bicolor (Dodd) [Australia], P. saccharalis (Dodd) [southern Europe, Africa, tropical Asia, Australia], P. ophiusa (Dodd) [Papua New Guinea, Australia], P. striativentris (Risbec) [Africa, India], and P. tetartus [Indonesia, Malaysia, Philippines] are redescribed. Aphanurus graeffei Kieffer, 1917 and Asolcus minor Watanabe, 1954 are junior synonyms of P. saccharalis (Dodd), 1913. An identification key to species is provided. The relationship of Paratelenomus within Telenominae is discussed; the hypothesized sister group is Nirupama Nixon.
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31

Baili, L., M. A. Farhati, B. Ben Dhaou, Z. Aydi, F. Boussema, S. Kochbati, J. Manaa, and L. Rokbani. "Angor mésentérique au cours d’une maladie de Takayasu : penser au syndrome du ligament arqué." La Revue de Médecine Interne 32 (December 2011): S355—S356. http://dx.doi.org/10.1016/j.revmed.2011.10.105.

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Pagnoni, Mattia, David Meier, Stephane Fournier, and Olivier Muller. "Syndrome coronarien chronique (angor stable) : indication à la revascularisation en 2020 et dernières évidences." Revue Médicale Suisse 16, no. 696 (2020): 1140–46. http://dx.doi.org/10.53738/revmed.2020.16.696.1140.

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33

De Meester, A., M. Vintila, R. Luca, and J. Col. "Angor Et Modifications Electrocardiographiques En Presence D’une Stenose Du Tronc Commun De L’artere Coronaire Gauche." Acta Clinica Belgica 50, no. 3 (January 1995): 158–62. http://dx.doi.org/10.1080/17843286.1995.11718440.

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34

Melero, A., R. Martinez, García R. de Sola, and E. De Teres. "Epidural electrical stimulation to relieve pain in patients with angor pectoris untractable by conventional therapy." Pain 30 (1987): S6. http://dx.doi.org/10.1016/0304-3959(87)91090-6.

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35

Haddad, F., G. Asmar, G. Maalouly, R. Abi Saleh, M. Jammal, S. Anouti, and G. Badawi. "Angor instable révélant une coronarite et une aortite chez un patient ayant une fièvre méditerranéenne familiale." La Revue de Médecine Interne 30 (December 2009): S461. http://dx.doi.org/10.1016/j.revmed.2009.10.374.

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36

Peñaloza Ramella, Dante. "El test cardiológico de anoxemia." Anales de la Facultad de Medicina 34, no. 4 (October 18, 2014): 677. http://dx.doi.org/10.15381/anales.v34i4.9548.

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Es perfectamente conocida la importancia fundamental del diagnóstico de certeza del síndrome de Angina de Pecho. Según White, este dindrome constituye el 11.8% de las cardiopatías, lo que demuestra que no es tan infrecuente, sobre todo en las últimas décadas. Es bien sabido, asimismo, el pronóstico relativamente grave de la estenocardia; en la estadística de White, el término medio de vida, después del primer ataque, solo alcanza a 9.1 años. Finalmente, es conocido que, una parte esencial del tratamiento preventivo de los ataques de angor pectoris, es el cambio radical en el modo de vida, lo cual puede acarrear, en muchos casos, consecuencias muy serias para el paciente, desde el punto de vista económico y social. Esta suerte de tratamiento, que interferiría fundamentalmente en la vida del paciente, así como el pronóstico que, como ya hemos dicho, es de relativa gravedad, sólo pueden hacerse justificadamente sobre la base de un diagnóstico indudable del sindrome de angina de pecho.
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37

Hajlaoui, N., F. Tarragano, P. Raisky, P. Beaufils, and P. Henry. "Angor spastique réfractaire au traitement médical traité par angioplastie avec mise en place d’un stent. À propos d’un cas et revue de la littérature." Annales de Cardiologie et d'Angéiologie 59, no. 2 (April 2010): 103–6. http://dx.doi.org/10.1016/j.ancard.2008.07.004.

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38

Taker, Abd Ali. "Effect of mercury on the total and electrophoretic profile of proteins and on the activity of three enzymes in mantle of three species of freshwater clam : Unio tigridis, Pseudontopsis euphraticus and Anodonta spp." Iraqi Journal of Veterinary Medicine 32, no. 1 (June 30, 2008): 166–79. http://dx.doi.org/10.30539/iraqijvm.v32i1.776.

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A three species of clam Unio tigridis, Pseudontopsis euphraticus andAnodonta sp. were collected from Al-Habaniya lake, Al-Angor region/Iraq.The animals were exposed to three concentrations of mercury :0.1, 0.2 and0.4 mg/L . First group of animals were exposed for three weeks ,secondgroup for two weeks and the third group for one week. At the end of theexposure period, the animals were dissected ,then the mantle removed for thefurther studies on proteins and enzymes. The results were :1- Total protein concentration in the mantle decreased in the threespecies of clam exposed to mercury. It was observed that aprominent effect of mercury on the electrophoretic bands ofproteins with the decrease in the intensity of protein bands orinduction of new bands.2- The activity of the three enzymes : Alkaline phosphatase , ALTand AST were not stable, either increasing or decreasingaccording to the different species and concentration of themercury , for example the activity of alkaline phosphataseincreased in the mantle of the first species at lower anddecreased at the second concentration but decreased in thirdspecies at different concentrations . The activity of ALTincreased in the mantle of the first species at all concentrationsof mercuy, while the activity of AST decreased in the mantle ofthe first species and increased at the two other concentrationsbut decreased in the mantle of third species .3- We concluded from this study that , the clam responses to themercury in the environment, which caused a changes in proteinsand enzymes. These changes can be used as an indicator to thewater pollution with the mercury .
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Ragone, María Inés, Matías Bayley, Germán A. Colareda, Patricia Bonazzola, and Alicia E. Consolini. "Cardioprotective Mechanisms of Hypothyroidism on Ischemia/Reperfusion in Rats and Effects of Carvedilol: Energetic Study." Journal of Cardiovascular Pharmacology and Therapeutics 25, no. 1 (September 8, 2019): 72–85. http://dx.doi.org/10.1177/1074248419872957.

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Hypothyroidism is considered a cardiac risk factor, but there is controversial evidence about its effects on coronary disease. The aim of this work was to evaluate the influence of hypothyroidism in rat hearts exposed to 2 degrees of stunning due to ischemia and reperfusion (I/R) as well as the underlying mechanisms. Hypothyroid (HypoT) rats were obtained by drinking 0.02% methimazole during 15 days. Isolated hearts were perfused and introduced in a flow calorimeter to measure contractile performance (P), total heat rate (Ht), and muscle economy (P/Ht). Hearts were exposed to 2 models of I/R, moderate and severe (respectively 20 or 30 minutes I/45 minutes R). Moreover, free cytosolic and mitochondrial calcium changes were measured by confocal fluorometry on cardiomyocytes. Comparison to euthyroid (EuT) hearts was done. Hypothyroidism was cardioprotective, but HypoT hearts were more sensitive than EuT hearts to the preischemic blockade of mitochondrial transporters mNCX and mKATP channels. Moreover, the postischemic recovery of P and P/Ht in HypoT hearts was strongly reduced by inhibition of the cellular pathways of PI3K/Akt and protein kinase C (PKC), and it was increased by nitric oxide synthase (NOS) inhibition. However, physiological concentrations of adrenaline reduced the cardioprotection of HypoT, but oral treatment with 20 mg/kg/day carvedilol prevented it. Results show that hypothyroidism reduces the mitochondrial Ca2+ overload during I/R by mKATP channel activation and Ca2+ extrusion through mNCX, while the PI3K/Akt and PKC pathways are involved in that cardioprotection. Contrarily, NOS activation and adrenaline blunt such cardioprotection, but carvedilol prevented the adrenergic dysfunction. These results would explain why hypothyroidism is a clinical risk factor in angor patients under adrenergic exacerbation but reduced the incidence of acute episodes of coronary syndrome in hospitalized patients. Results suggest that a treatment with carvedilol could be a potential therapeutic agent to prevent cardiac postischemic dysfunction in hypothyroid patients.
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Aityahya, A., M. A. Charik, M. Eljamili, and M. Elhattaoui. "Acute Coronary Syndrome without ST Elevation: is The Level of Ultrasensitive Troponin T Correlated to the Severity of Coronary Involvement?" SAS Journal of Medicine 8, no. 3 (March 23, 2022): 188–92. http://dx.doi.org/10.36347/sasjm.2022.v08i03.015.

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Introduction: Acute coronary syndromes without ST segment elevation are heterogeneous entities. Troponins contribute to the early identification of patients at high risk for cardiac complications. The objective of this work is to study the severity of coronary artery disease according to the ultrasensitive troponin T (T us) level. Methods: We have performed a descriptive retrospective of patients hospitalized in the cardiology department of CHU Mohammed VI in Marrakech, between January 2018 and February 2022 for acute coronary syndromes without ST segment elevation. Patients were divided into two groups according to the rate of troponin Tus. Results: 50 patients were included, comprising 35 men and 15 women. Group 1, made of 20 patients whose ultrasensitive troponin T level is less than 4 times normal, group 2, whose troponin T level is more than 4 times normal, made of 30 patients. Demographic analysis shows that there is no significant difference between the two groups in terms of average age and sex. Hypertension is slightly more common in Group 1 (45% vs. 43.3%). De novo angor was more frequent in group 1 compared to group 2 (10% vs 6.7%;p=0.01). At electrocardiogram, subendocardial lesions are more in Group 2 (15% vs. 43.3%; p=0.0006). Group 1 had angiographical coronaries more frequently normal or non-significant coronary involvement compared to group 2 (40% vs 6.67%; p<0.001). Tritroncular lesions are more frequently found in Group 2 (33.3% vs. 5%;p=0.02). Monotroncular and bi-roncular lesions are recorded identically in both groups. Ischemic recurrences are more common in Group 2 (35% vs. 46.6%;p=0.02). Conclusion: Stable Troponin US levels are associated with the degree of coronary involvement, and frailty measurements were significantly associated with the severity of coronary lesions, this could help to identify patients who are at a high risk of death. These findings may help clinicians guide further diagnostic assessment.
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41

Kumar, Sella. "Management of Anger with Anger Reversal Technique among School Going Adolescents." International Journal of Psychology and Educational Studies 4, no. 3 (September 1, 2017): 32–41. http://dx.doi.org/10.17220/ijpes.2017.03.004.

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42

Gil-Negrete, A., J. M. Mañe, A. Ruiz de Lobera, A. Martinez-Bueno, I. Rubio, N. Fuente, G. Lopez-Vivanco, N. Ancizar, R. Fernandez, and A. Sancho. "First-line docetaxel (Dx) and capecitabine (Cap) in advanced head and neck cancer." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 16505. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.16505.

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16505 Background: Dx and Cap are useful drugs in head and neck cancer. Our purpose was to establish the efficacy and safety of this combination in non selected patients (pts) with advanced or metastatic (M1) head and neck cancer. Methods: : Between Apr 2005 and Nov 2006, 33 pts with squamous cell locally advanced or M1 head and neck cancer received the following chemotherapy (Ct) schedule: Dx 75 mg/m2 day 1 and Cap 950 mg/m2/12h days 2–14, every 3 weeks.30 pts (90.9%) had received previous local radiotherapy, 11 of them with concomitant Ct. Results: Mean age was 60 years old (range 46–75). M/F: 32/1. PS 0/1/2: 1/29/3. Location of disease: only local 49%; local and M1 36%; only M1 15% (Main M1 site: lung 76.5%, nodes 11.8%, bone 5.9%, soft tissue 5.9%). Mean number of Ct cycles: 4 (range 1–7). Worst hematologic toxicities per patient G3/G4 (%): neutropenia 6/39; febrile neutropenia 36/0; anemia 3/0; trombopenia 3/3. Non-hematologic toxicities G2/G3 (%): vomiting 3/3; neuropathy 6/0; asthenia 33/6; diarrhea 21/3; mucositis 33/18; nail changes 12/0; hand foot syndrome 3/12. Other events to remark: 4 pts had neumonia (2 toxic deaths), 1 pts had angor and required a different Ct schedule, 2 pts had massive hemorrage (1 exitus). There were 7 pts not evaluable for response (4 not yet evaluated, 1 early death due to massive hemorrage, 1 toxic death due to neumonia, 1 early disphagia). Among the evaluated pts, responses were: 2 CR (7.7%), 10 PR (38.5%), 9 SD (34.6%) and 5 PD (19.2%). Median TTP was 21 weeks (95%CI 17.5 - 24.2). Median OS was 39.8 weeks (95%CI 32.4 - 47.4) by Kaplan-Meier method. Conclusions: This combination appears to be active in pts with advanced or M1 head and neck cancer. Main toxicities were neutropenia, febrile neutropenia, mucositis and asthenia. Global toxicity was important with two toxic deaths documented No significant financial relationships to disclose.
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Mert, Eda, Fatma Demirkıran, and Filiz Adana. "RELATION BETWEEN INTERPERSONAL RELATIONSHIP DIMENSIONS AND TRAIT ANGER-ANGER EXPRESSION IN NURSING STUDENTS." E-journal of New World Sciences Academy 14, no. 2 (April 29, 2019): 122–32. http://dx.doi.org/10.12739/nwsa.2019.14.2.1b0073.

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Choi, Sanghee, Taehee Jung, and Kwangsoo Kim. "분노조절 프로그램이 아동의 분노 및 공격성에 미치는 영향." Korean Journal of Elementary Counseling 17, no. 1 (January 31, 2018): 29–45. http://dx.doi.org/10.28972/kjec.2018.17.1.029.

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Martin Liberal, Juan, José Pablo Maroto, Begoña Mellado, Ferran Ferrer, Gemma Sancho, Angels Rovirosa, Francesc Vigues, et al. "Phase I trial of sorafenib with concurrent radiotherapy (RT) in patients with invasive bladder cancer treated with bladder-sparing intent: A Spanish Oncology Genitourinary Group study." Journal of Clinical Oncology 30, no. 5_suppl (February 10, 2012): 270. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.270.

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270 Background: Preclinical studies suggest enhanced radiation-induced cell death when VEGFR inhibitor therapies are combined with RT. Methods: Patients with localized muscle invasive urothelial carcinoma of the bladder in clinical stage T2-3 N0 M0, who were not eligible or rejected radical cystectomy, ECOG PS 0-2, and adequate hematological, renal and hepatic function, were enrolled in this phase I study to assess safety and identify the dose limiting toxicity (DLT), maximum tolerated dose (MTD) and recommended dose (RD) of sorafenib and RT. A 3+3 dose escalation design with cohorts of 3-6 patients was used. Treatment consisted of TUR, followed by normofractionated (2 Gy/day) external-beam RT with high-energy photons, 46 Gy to minor pelvis and 66 Gy to bladder, combined with sorafenib given po continuously. Sorafenib was started two weeks before RT and was administered for 12 weeks, finishing 4 weeks after RT. Dose levels 1, 2 and 3 corresponded to sorafenib 200 mg qd, 200 mg bid and 800 mg bid. Pathological response was assessed by post-treatment TUR. Results: Ten patients were included: median age 71 years (44-84); gender 7M: 3F. Patients were treated at 3 dose levels, the MTD was reached at level 3 and the RD was: sorafenib 200 mg bid with RT. Two DLTs occurred, both at the third dose level: diarrhea grade 3 and digestive bleeding grade 3 with secondary anemia and hemodynamic angor in a patient with previous small bowel angiodysplasia. The most frequent toxicity was diarrhea. Other grade 1-2 toxicities included rash, fatigue, hand-foot syndrome, hypertension, dysuria and urinary frequency. One patient developed late radiation cystitis. Pathological complete response was achieved in 8 of 9 patients evaluated. Salvage cystectomy has been performed in one patient due to recurrent superficial bladder tumor. After a median follow up of 30 months, 6 patients remain disease-free with intact bladder. Conclusions: The combination of sorafenib and RT appears to be feasible and safe allowing long-term bladder preservation in selected patients. A phase II study to assess the activity of this promising combination is warranted.
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Yarovikova, Y. V. "A Lexicographic Description of the Concept “Anger”." Язык и текст 7, no. 1 (2020): 121–27. http://dx.doi.org/10.17759/langt.2020070112.

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The paper seeks to outline the content of the concept “anger” as it is represented both in print and online lexicographic resources. The study is based upon the data gained directly from mono- and bilingual thesauruses, dictionaries of etymology, phraseology and idioms. The subject of the study is the semantic structure of the lexeme “anger” that names the corresponding concept in the English language. Etymological, definitional and contextual analyses revealed the lexeme’s diachronic transformations that underlie its semantics in Modern English. The data obtained in the analyses also contributed to identifying a wide range of usual cognitive characteristics that constitute the notional component of the concept. The choice of this issue is determined primarily by linguists’ continuing interest in representing a person’s interior by language means. The findings of the study make a contribution to the further development of issues relating to the linguistic expression of the human inner world in Modern Germanic languages from linguocognitive and anthropological perspectives.
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Farkas, Attila. "Ethnic stereotypes in the English pamphlet literature." Studia Mundi - Economica 2, no. 3 (2015): 21–32. http://dx.doi.org/10.18531/studia.mundi.2015.02.03.21-32.

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Ingerpuu, Nele, Kai Vellak, Anders Hagborg, and Lars Söderström. "The Angkor Wat Kingdomliverworts from Cambodia." Nova Hedwigia, Beihefte 150 (July 28, 2020): 293–316. http://dx.doi.org/10.1127/nova-suppl/2020/293.

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Besharat, Mohammad Ali, and Shahriar Shahidi. "Perfectionism, anger, and anger rumination." International Journal of Psychology 45, no. 6 (December 2010): 427–34. http://dx.doi.org/10.1080/00207594.2010.501336.

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LeCroy, Craig Winston. "Anger Management or Anger Expression." Residential Treatment For Children & Youth 5, no. 3 (August 9, 1988): 29–39. http://dx.doi.org/10.1300/j007v05n03_04.

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