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Relevant bibliographies by topics / Animal biotechnology – Research

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Academic literature on the topic 'Animal biotechnology – Research'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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Journal articles on the topic "Animal biotechnology – Research"

1

Rexroad, C. E., R. D. Green, and R. J. Wall. "Regulation of animal biotechnology: Research needs." Theriogenology 68 (September 2007): S3—S8. http://dx.doi.org/10.1016/j.theriogenology.2007.03.017.

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Nguyen, Bach Duc, and Bich Thuy Thi Ly. "Current Research, Challenges, and Perspectives of Biotechnology: An Overview." Vietnam Journal of Agricultural Sciences 1, no. 2 (2019): 187–99. http://dx.doi.org/10.31817/vjas.2018.1.2.09.

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Biotechnology is defined as biology-based technology using organisms or their parts to make or modify products or to improve characteristics of plants, animals, and microorganisms for the demands of human beings. Biotechnology profoundly impacts various fields such as agriculture, animal husbandry and veterinary, industry, food science, pharmaceutics and medicine, environment, fine chemistry, biofuels, forensics, and nanotechnology. Nowadays, biotechnology and bioindustries are becoming integral parts of the knowledge-based economy, and therefore, biotechnology has become a powerful and indispensable tool for the development of all countries in the world. As a rule, biotechnology also requires regulatory policies to control genetically modified organisms and derived products to avoid risks to biodiversity, human health, the environment, and ethical issues. This article reviews the current research, challenges, and perspectives of biotechnology as an integration of both life sciences and applied sciences.

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Nicoll, Charles S., and Sharon M. Russell. "Animal Research vs. Animal Rights." FASEB Journal 3, no. 5 (1989): 1668–722. http://dx.doi.org/10.1096/fasebj.3.5.2646165.

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Fiester, Autumn. "Justifying a Presumption of Restraint in Animal Biotechnology Research." American Journal of Bioethics 8, no. 6 (2008): 36–44. http://dx.doi.org/10.1080/15265160802248138.

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Thompson, Paul B. "Current ethical issues in animal biotechnology." Reproduction, Fertility and Development 20, no. 1 (2008): 67. http://dx.doi.org/10.1071/rd07184.

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The present paper reviews the current status of opinion and debate regarding ethical issues in three broad categories of relevance to animal biotechnology. The first is scientific integrity, where the focus has been on scientific fraud and the integrity of the research process. The second concerns possible harms or risks to parties affected either directly by research (including animals themselves) or through the eventual commercialisation or development of products from animal biotechnology. The final category concerns a responsibility to serve as a guardian of the public interest with respect to application and development of technologies derived from new genetic sciences. It is plausible to see the scientific community as a whole having such a fiduciary obligation to the broader public in virtue of the technical complexity of the issues and owing to the public funding and institutional support for scientific research. The overall conclusion is that in the latter two categories especially, there is an urgent need for new participation in deliberative consideration of ethical issues by working scientists.

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GAVORA, JAN S. "BIOTECHNOLOGY IN ANIMAL SCIENCE: CHALLENGES AND OPPORTUNITIES." Canadian Journal of Animal Science 65, no. 3 (1985): 525–26. http://dx.doi.org/10.4141/cjas85-063.

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Several new, powerful techniques for the manipulation of living cells and their components are globally referred to as biotechnology. They have the potential to bring about dramatic improvements in livestock production. The Symposium papers that follow review the relevant advances and consider the role of biotechnology in future animal production research. Key words: Biotechnology, animal science, genetic engineering, rumen microflora, embryo manipulation

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Robinson, J. J. "Biotechnology - The possibilities." Proceedings of the British Society of Animal Production (1972) 1993 (March 1993): 24. http://dx.doi.org/10.1017/s0308229600023539.

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An increasing proportion of Agricultural Research funding is being directed to biotechnology and to cell and molecular biology. This shift in funding has two effects on animal production research. First it provides a certain amount of novel information and technology with which to improve current production systems. Second, it leaves less of the research budget for whole animal experiments. It behoves us therefore to keep abreast of the achievements and aspirations of the molecular and cellular biologists. The diverse interests and expertise of the BSAP membership in research, development, advisory work and teaching make the Society a unique forum for conducting the open and on-going debate that is needed to ensure that the results of modern biotechnology are examined critically and applied to the animal production industries in an efficient and acceptable manner.

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Ung-Lanki, Sari. "Constructing the Biotech Nonhuman Animal: Instrumentalism and Ambivalence." Society & Animals 22, no. 5 (2014): 439–58. http://dx.doi.org/10.1163/15685306-12341349.

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This article was designed to give insight into the role of biotechnology in redefining the complex human-animal relations of our times. In particular, it is used to examine accounts of nonhuman animals and animal usage in the context of biotechnology, as covered in the leading scientific journalNature Biotechnology. Data consist of editorials, commentaries, and research news for four years (N= 104), and has been analyzed using discourse analysis. The journal constructs a consistent, yet one-sided, view on animals as they are represented through physico-material, technical and biomedical discourses, as well as discourses on human benefits and manageable risks. The biotechnological epistemology of the animal is positioned at the far end of the subjectification-instrumentalization continuum in our treatment of other animals. It also clashes with simultaneous discussions on animal mind, subjectivity, and moral status. These developments are likely to further intensify the discrepancies in human-animal relations in science and society.

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Bailone, Ricardo Lacava, Luís Kluwe de Aguiar, Roberto de Oliveira Roca, et al. "“Zebrafish as an animal model for food safety research: trends in the animal research”." Food Biotechnology 33, no. 4 (2019): 283–302. http://dx.doi.org/10.1080/08905436.2019.1673173.

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Conn, P. Michael, and James V. Parker. "The animal research war." FASEB Journal 22, no. 5 (2008): 1294–95. http://dx.doi.org/10.1096/fj.08-0502ufm.

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Dissertations / Theses on the topic "Animal biotechnology – Research"

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Pan, Shu St George Clinical School UNSW. "Functional studies of transcription factors GATA-1, Fli-1 and FOG-1 in Megakaryocyte development." 2007. http://handle.unsw.edu.au/1959.4/40591.

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Transcription factors GATA-1, Fli-1 and FOG-1 are essential proteins for normal megakaryopoiesis, however, the detailed analyses of their functions within developmental stages of megakaryopoiesis are lacking. In my thesis, over expression of gene in target cells was adopted as the main strategy to study the biological functions of these proteins, therefore, an efficient gene delivery method was first developed by using retrovirus.This approach was then utilized to over express GATA-1, Fli-1 and FOG-1 in murine leukemia M1 cells and mouse hematopoietic stem cells (HSCs), and their effects on different developmental stages of megakaryopoiesis were investigated. In the transduced M1 cells, enforced expression of GATA-1 and Fli-1 was found to induce the megakaryocytic development, which was associated with the formation of megakaryocyte (Mk) and the increased expression of Mk specific genes c-Mpl and GPIX. In the transduced mouse HSCs, it was found that the expression of endogenous GATA-1, Fli-1 and FOG-1 was up-regulated throughout Mk differentiation; enforced expression of these transcription factors led to the significantly enhanced Mk development. Megakaryocytes over expressing GATA-1, Fli-1 and FOG-1 were characterized by the increased expression of various Mk-specific genes including GPIX, c-Mpl, platelet factor 4 (PF4), acetylcholinesterase (AChE) and NF-E2, an important transcription factor for terminal megakaryopoiesis; however, GATA-1, Fli-1 and FOG-1 displayed the different abilities in promoting the proliferation of hematopoietic cells and MK differentiation, as well as regulating other transcription factors involved in hematopoiesis. To further elucidate the role of the functional domains of Fli-1, various mutants of Fli-1 were also over expressed in mouse HSCs. The results demonstrated that first, the combination of the activation domain of Fli-1 and its Ets domain is required for early megakaryopoiesis but not sufficient for terminal megakaryopoiesis; second, DNA binding of Fli-1 was not the only requirement for early Mk enhancement, moreover, the interaction between Fli-1 and GATA-1 through the Ets domain and the resultant transcriptional synergy was the essential determinant for Fli?1 ability in Mk development. Taken together, the studies presented in this thesis provided strong in vitro evidence that GATA-1, Fli-1 and FOG-1 indeed play the critical roles in normal megakaryopoiesis.

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Chihara, Ray K. "Study of Physiologic and Immunologic Incompatibilities of Pig to Human Transplantation." Thesis, 2014. http://hdl.handle.net/1805/5280.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Solid organ transplantation is limited by available donor allografts. Pig to human transplantation, xenotransplantation, could potentially solve this problem if physiologic and immunologic incompatibilities are overcome. Genetic modifications of pigs have proven valuable in the study of xenotransplantation by improving pig to human compatibility. More genetic targets must be identified for clinical success. First, this study examines platelet homeostasis incompatibilities leading to acute thrombocytopenia in liver xenotransplantation. Mechanisms for xenogeneic thrombocytopenia were evaluated using liver macrophages, Kupffer cells, leading to identification of CD18, beta-2 integrin, as a potential target for modification. When disruption of CD18 was accomplished, human platelet binding and clearance by pig Kupffer cells was inhibited. Further, human and pig platelet surface carbohydrates were examined demonstrating significant differences in carbohydrates known to be involved with platelet homeostasis. Carbohydrate recognition domains of receptors responsible for platelet clearance Macrophage antigen complex-1 (CD11b/CD18) and Asialoglycoprotein receptor 1 in pigs were found to be different from those in humans, further supporting the involvement of platelet surface carbohydrate differences in xenogeneic thrombocytopenia. Second, immunologic incompatibilities due to antibody recognition of antigens resulting in antibody-mediated rejection were studied. Identification of relevant targets was systematically approached through evaluation of a known xenoantigenic protein fibronectin from genetically modified pigs. N-Glycolylneuraminic acid, a sialic acid not found in humans, was expressed on pig fibronectin and was identified as an antigenic epitope recognized by human IgG. These studies have provided further insight into xenogeneic thrombocytopenia and antibody-mediated rejection, and have identified potential targets to improve pig to human transplant compatibility.

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Himes, Evan Robert. "The role of STAT3 in osteoclast mediated bone resorption." Thesis, 2014. http://hdl.handle.net/1805/4841.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Signal Transducer and Activator of Transcription 3 (STAT3) is known to be related to bone metabolism. Mutation of STAT3 causes a rare disorder in which serum levels of IgE are elevated. This causes various skeletal problems similar to osteoporosis. To examine the effect of STAT3 in the osteoclast, we obtained two osteoclast specific STAT3 knockout mouse models: one using the CTSK promoter to drive Cre recombinase and another using a TRAP promoter. Examination of these mice at 8 weeks of age revealed a decreased trabecular bone volume in CTSK specific STAT3 knockout mice along with a slight decrease in osteoclast number in both CTSK and TRAP specific STAT3 knockout females. We also noticed changes in bone mineral density and bone mechanical strength in females. These data suggest that STAT3 plays a part in the function of the osteoclast.

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Placinta, Mike. "A New Laser Pointer Driven Optical Microheater for Precise Local Heat Shock." 2009. https://scholarworks.umass.edu/theses/328.

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The zebrafish has emerged as an important genetic model system for the study of vertebrate development. However, while genetics is a powerful tool for the study of early gene functions, the approach is more limited when it comes to understanding later functions of genes that have essential roles in early embryogenesis. There is thus a need to manipulate gene expression at different times, and ideally only in some regions of the developing embryo. Methods for conditional gene regulation have been established in Drosophila, C.elegans and the mouse, utilizing conditional gene activation systems such as the Gal4-UAS system (fly) and the cre/lox recombination system (mouse). While these tools are also being developed in zebrafish, the accessibility of the zebrafish embryo makes other approaches both possible and desirable. We have taken advantage of a heat-shock inducible system that uses the hsp70 promoter that is activated by cellular stress, such as heat. Having established that this global heat shock method allows temporal control of gene expression, we aimed to spatially control gene expression by applying controlled thermal heat to only a small region of the embryo. This would allow us to determine cell- and tissue-autonomous roles for developmentally important genes in an embryo with otherwise normal gene function. We have now developed a device that uses a laser to heat a defined region of the embryo, and thus activate the hsp70 promoter only in restricted regions of the embryo. The output of a 75 mW red laser pointer was focused into the 50 µm diameter core of an optical fiber, whose cleaved and coated end was used to heat, and thus induce, gene expression in a defined area. We have established conditions that allow controlled heating and trans-gene activation in small regions of the embryo without inducing cell death. This new tool will allow us to study the cell-autonomous roles of embryonic signaling molecules in cell differentiation, proliferation, and survival in a variety of tissues and at different times.

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Books on the topic "Animal biotechnology – Research"

1

NATO, Advanced Research Workshop on Advances in Animal Cell Technology (1987 Brussels Belgium). Advanced research on animal cell technology. Kluwer Academic, 1989.

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2

Nanis, Suzanne. Biotechnology: Gene transfer in animal systems, January 1979 - November 1989. U.S. Dept. of Agriculture, National Agricultural Library, 1989.

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National Conference on Plant and Animal Biotechnology (1990 Nairobi, Kenya). Biotechnology in Kenya: Proceedings of the National Conference on Plant and Animal Biotechnology, held February 25-March 3, 1990 at Kenyatta International Conference Centre, Nairobi, Kenya. Edited by Mailu A. M, Mugah J. O, Fungoh P. O, and Kenya Agricultural Research Institute. Initiatives Publishers, 1991.

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Belcher, Brian. A patent on life: Ownership of plant and animal research. International Development Research Centre, 1991.

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Belcher, Brian. A patent on life: Ownership of plant and animal research. International Development Research Centre, 1991.

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Nanis, Suzanne. Biotechnology: Gene mapping in insects and animal systems, January 1979 - April 1989 : 118 citations. U.S. Dept. of Agriculture, National Agricultural Library, 1989.

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Scientific and humane issues in the use of random source dogs and cats in research. National Academies Press, 2009.

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R, Spier, Griffiths J. B, and Oholo Biological Conference (32nd : 1987 : Tiberias, Israel), eds. Modern approaches to animal cell technology: ESACT, European Society for Animal Cell Technology, the 8th meeting, Oholo Biological Conference, Israel Institute for Biological Research, the 32nd conference. Butterworths, 1987.

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International, SABRAO Congress (7th 1993 Taipei Taiwan R. O. C. ). Toward enhanced and sustainable agricultural productivity in the 2000's: Breeding research and biotechnology : proceedings of SABRAO seventh International Congress and WSAA Symposium held at Academia Sinica, Nankang, Taipei, Taiwan, R.O.C., November 16-20, 1993. Taichung District Agricultural Improvement Station in association with the Society for the Advancement of Breeding Researches in Asia and Oceania, 1994.

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Organisation for Economic Co-operation and Development. Workshop. Novel systems for the study of human disease: From basic research to applications : OECD proceedings. OECD, 1998.

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Book chapters on the topic "Animal biotechnology – Research"

1

Singh, Birbal, Gorakh Mal, Sanjeev K. Gautam, and Manishi Mukesh. "Transcriptomics: Genome-Wide Expression Analysis in Livestock Research." In Advances in Animal Biotechnology. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-21309-1_33.

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Babiuk, L. A. "Biotechnology Applied in Animal Vaccine Development and Production." In Biotechnology Research and Applications. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1371-4_2.

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Fraser, Ann D. E. "Applications of Biotechnology to the Diagnoses of Animal Diseases." In Biotechnology Research and Applications. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1371-4_3.

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Petricciani, John C. "Use of Cell Lines in Biotechnology." In Advanced Research on Animal Cell Technology. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-0875-8_5.

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Nieuwenweg, Anna Cornelia, Benjamin D. Trump, Katarzyna Klasa, Diederik A. Bleijs, and Kenneth A. Oye. "Emerging Biotechnology and Information Hazards." In NATO Science for Peace and Security Series C: Environmental Security. Springer Netherlands, 2021. http://dx.doi.org/10.1007/978-94-024-2086-9_9.

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AbstractBiotechnology innovation has never been more accessible to individuals, companies, and (research)organizations. Advances in genetic engineering, declining costs, and improved education have improved access to biotechnologies. Such openness has provided many benefits as biotechnology has been used to address some of the world’s most intractable problems However, increased access to biotechnology tools and knowledge may also pose risks to humans, animals, and the environment (Meyer 2013; Kera 2014; Li et al. 2017; Oye 2012).

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Nishu, Nishu, Shet Masih, Shivali Kamal, Pooja Jain, and Zafar K. Khan. "Transgenic animals in research and industry." In Animal Biotechnology. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-811710-1.00021-5.

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Datta, Amrita, and Debasis Mondal. "Development of Mouse Models for Cancer Research." In Animal Biotechnology. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-416002-6.00005-5.

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Chandra, Partha K., Amrita Datta, and Debasis Mondal. "Development of mouse models for cancer research." In Animal Biotechnology. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-811710-1.00005-7.

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Suckow, Mark A., and Jessica L. Gimpel. "Approaches to the humane euthanasia of research animals." In Animal Biotechnology. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-811710-1.00037-9.

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Pore, Debasis, Kazi Mirajul Hoque, and Manoj K. Chakrabarti. "Animal models in advancement of research in enteric diseases." In Animal Biotechnology. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-811710-1.00032-x.

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Conference papers on the topic "Animal biotechnology – Research"

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Dygert, Joseph P., Melissa L. Morris, Erik M. Messick, and Patrick H. Browning. "Feasibility of an Energy Efficient Large-Scale Aquaponic Food Production and Distribution Facility." In ASME 2014 8th International Conference on Energy Sustainability collocated with the ASME 2014 12th International Conference on Fuel Cell Science, Engineering and Technology. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/es2014-6567.

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Today the United States is plagued by societal issues, economic insecurity, and increasing health problems. Societal issues include lack of community inclusion, pollution, and access to healthy foods. The high unemployment coupled with the rising cost of crude oil derivatives, and the growing general gap between cost of living and minimum wage levels contribute to a crippled consumer-driven US economy. Health concerns include increasing levels of obesity, cardiovascular disease, cancer, and diabetes. These epidemics lead to staggering economic burdens costing Americans hundreds of billions of dollars each year. It is well-known that many of the health issues impacting Americans can be directly linked to the production, availability, and quality of the food. Factors contributing to the availability of food include reduction of United States farmland, an increase in food imported from overseas, and the cost of goods to the consumer. The quality of food is influenced by the method of growth as well as imposed preservation techniques to support food transportation and distribution. At the same time, it has become increasingly common to implement biotechnology in genetically modified crops for direct human food or indirectly as a livestock feed for animals consumed by humans. Crops are also routinely dosed with pesticides and hormones in an attempt to increase productivity and revenue, with little consideration or understanding of the long term health effects. Research shows that community gardens positively impact local employment, community involvement and inclusivity, and the diets of not only those involved in food production, but all members of their households. The purpose of this work is to determine the feasibility of an energy efficient large-scale aquaponic food production and distribution facility which could directly mitigate growing socioeconomic concerns in the US through applied best practices in sustainability. Aquaponics is a symbiotic relationship between aquaculture and hydroponics, where fish and plants grow harmoniously. The energy efficient facility would be located in an urban area, and employ solar panels, natural lighting, rain water reclamation, and a floor plan optimized for maximum food yield and energy efficiency. Examples of potential crops include multiple species of berries, corn, leafy vegetables, tomatoes, peppers, squash, and carrots. Potential livestock include responsibly farmed tilapia, shrimp, crayfish, and oysters. The large scale aquaponic facility shows a lengthy period for financial return on investment whether traditional style construction of the building or a green construction style is used. However many forms of federal government aid and outside assistance exist for green construction to help drive down the risk in the higher initial investment which in the long run could end up being more profitable than going with a traditionally constructed building. Outside of financial return there are many proven, positive impacts that a large-scale aquaponic facility would have. Among these are greater social involvement and inclusivity, job creation, increased availability of fresh food, and strengthening of America’s agriculture infrastructure leading to increased American independence.

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