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Journal articles on the topic 'Animal studies bone and bones'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Morey-Holton, Emily R., Bernard P. Halloran, Lawrence P. Garetto, and Stephen B. Doty. "Animal housing influences the response of bone to spaceflight in juvenile rats." Journal of Applied Physiology 88, no. 4 (2000): 1303–9. http://dx.doi.org/10.1152/jappl.2000.88.4.1303.

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The rat has been used extensively as an animal model to study the effects of spaceflight on bone metabolism. The results of these studies have been inconsistent. On some missions, bone formation at the periosteal bone surface of weight-bearing bones is impaired and on others it is not, suggesting that experimental conditions may be an important determinant of bone responsiveness to spaceflight. To determine whether animal housing can affect the response of bone to spaceflight, we studied young growing (juvenile) rats group housed in the animal enclosure module and singly housed in the research

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Doty, S. B., E. R. Morey-Holton, G. N. Durnova, and A. S. Kaplansky. "Morphological studies of bone and tendon." Journal of Applied Physiology 73, no. 2 (1992): S10—S13. http://dx.doi.org/10.1152/jappl.1992.73.2.s10.

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The Soviet biosatellite COSMOS 2044 carried adult rats on a spaceflight that lasted 13.8 days and was intended to repeat animal studies carried out on COSMOS 1887. Skeletal tissue and tendon from animals flown on COSMOS 2044 were studied by light and electron microscopy, histochemistry, and morphometric techniques. Studies were confined to the bone cells and vasculature from the weight-bearing tibias. Results indicated that vascular changes at the periosteal and subperiosteal region of the tibia were not apparent by light microscopy or histochemistry. However, electron microscopy indicated tha

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Payne, Sebastian. "Animal Bones from Aşıklı Hüyük." Anatolian Studies 35 (December 1985): 109–22. http://dx.doi.org/10.2307/3642877.

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Aşıklı Hüyük, a large Aceramic Neolithic mound in the Melendizsuyu valley, some 25 km. SE of Aksaray (prov. Niğde), was visited in 1964 by Ian Todd, who collected a very large quantity of obsidian tools and flakes from the surface, and, at the same time, was able to collect samples including animal bones, charcoal and seeds from a large section cut by the river into the side of the mound (Todd 1966). The obsidian industry suggested a date earlier than Çatal Hüyük East, and this was confirmed by a series of five 14C dates between 7008±130 bc and 6661±108 bc (using the 5568±30 yr half-life) (Tod

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Marean, Curtis W., and Carol J. Frey. "Animal Bones from Caves to Cities: Reverse Utility Curves as Methodological Artifacts." American Antiquity 62, no. 4 (1997): 698–711. http://dx.doi.org/10.2307/281887.

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Utility-based studies are attractive to zooarchaeologists because they afford the opportunity of investigating economic decisions relative to particular contexts. While a positive relationship between utility and skeletal element abundance is anticipated at residential sites, a reverse utility curve is most common. A popular mechanistic explanation argues that reverse utility curves result from density-mediated destruction of bone, suggesting that utility-based studies will rarely be successful as density-mediated destruction will overwhelm any skeletal element patterning created by differenti

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Forwood, Mark R. "Physical activity and bone development during childhood: insights from animal models." Journal of Applied Physiology 105, no. 1 (2008): 334–41. http://dx.doi.org/10.1152/japplphysiol.00040.2008.

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Animal studies illustrate greater structural and material adaptations of growing bone to exercise than in adult bones but do not define effective training regimes to optimize bone strength in children. Controlled loading studies in turkey, rat, or mouse bones have revealed mechanisms of mechanotransduction and loading characteristics that optimize the modeling response to applied strains. Insights from these models reveal that static loads do not play a role in mechanotransduction and that bone formation is threshold driven and dependent on strain rate, amplitude, and partitioning of the load.

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Mohd Salleh, Mohd Mahyeddin, and Irwan Mohd Subri. "Fatwa Analysis on Bone China Products and Its Halal Solution." Ulum Islamiyyah 23 (April 5, 2018): 53–66. http://dx.doi.org/10.33102/uij.vol23no0.18.

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This article discusses the use of animal bones in bone China products from halal and haram perspective. The main problem of the study due to the public confusion as a result of the difference views on halal and haram status of bone China products. The objectives of the study are to analyze the Shariah’s view and current fatwa on the law of utilizing animal bones, thus proposing a halal legal solution to the issue studied. The qualitative research methodology was used in this study through two approaches which are document analysis and interview. The study found that the cattle bones were the r

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Rosca, J. C. Mirza, N. R. Florido Suárez, L. Baltes, and M. Tierean. "Biomechanical properties of animals bones and the influence of oncologic drug on pig femur." IOP Conference Series: Materials Science and Engineering 1262, no. 1 (2022): 012025. http://dx.doi.org/10.1088/1757-899x/1262/1/012025.

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Over the years, we have seen how, thanks to experimentation on animal models, the foundations have been laid in the field of implantology. In most cases, studies related to the bone scale are carried out on the species that are most similar in their movements and behavior to humans. The femur has been selected as the reference bone for our test, selecting as animals to experiment with the goat breed, the bovine breed and the porcine breed for their similarity to the human body, obtaining specimens of the cortical part of the bone. Destructive bending tests will be carried out in the same way o

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Vorontsov, Petro, and Valentyna Maltseva. "A REVIEW OF ANIMAL MODELS FOR BONE FRACTURE NONUNION AND THEIR ROLE IN STUDYING BIOLOGICAL THERAPY EFFICACY." ORTHOPAEDICS TRAUMATOLOGY and PROSTHETICS, no. 2 (July 9, 2024): 81–87. http://dx.doi.org/10.15674/0030-59872024281-87.

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The bone healing impairment, such as non-union fractures after injuries of long bones, lead to loss of working capacity and result in significant financial costs, which emphasizes the socioeconomic significance of the problem. However, it is not known which method of modeling the non-union bone fractures is more optimal for further research into the effectiveness of biological therapy aimed at treating bone healing impairment. For a detailed study of methods of non-union fracture treatment of, it is necessary to determine the developed animal models. The objective was to analyze the existing a

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Huang, Xiaowei, Andreas K. Nussler, Marie K. Reumann, et al. "Contribution to the 3R Principle: Description of a Specimen-Specific Finite Element Model Simulating 3-Point-Bending Tests in Mouse Tibiae." Bioengineering 9, no. 8 (2022): 337. http://dx.doi.org/10.3390/bioengineering9080337.

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Bone mechanical properties are classically determined by biomechanical tests, which normally destroy the bones and disable further histological or molecular analyses. Thus, obtaining biomechanical data from bone usually requires an additional group of animals within the experimental setup. Finite element models (FEMs) may non-invasively and non-destructively simulate mechanical characteristics based on material properties. The present study aimed to establish and validate an FEM to predict the mechanical properties of mice tibiae. The FEM was established based on µCT (micro-Computed Tomography

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Ridouh, Rania, Faiza Tekkouk-Zemmouch, Chantal Thorin, and Claude Guintard. "Prédiction du sexe à partir d'un échantillon de métacarpes de chèvres (Capra hircus L., 1758) de race Arabia (Algérie) : réalisation d'un référentiel pour l'archéozoologie." Revue de Paléobiologie 38, no. 1 (2019): 255–65. https://doi.org/10.5281/zenodo.3265247.

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Sex prediction from a sample of goat metacarpal bones (Capra hircus, L. 1758) of Arabia breed (Algeria) : realization of a reference database for zooarchaeological studies.- Sex prediction from bones coming from archaeological sites require tools of comparison and reference collections which are the closest possible to the studied morphological types. The local Algerian goat (Arabia) is, from this point of view, an old population of small to medium size animals which perfectly caters to the expectations of the zooarchaeologists. The analysis of sexual dimorphism in the caprine species i

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Liebowitz, Harold. "Bare Bones: Ancient Artifacts from Animal Bones. Etan Ayalon and Chagit Sorek." Bulletin of the American Schools of Oriental Research 322 (May 2001): 94–95. http://dx.doi.org/10.2307/1357525.

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Ehrenkranz, Joel, and Michael A. Levine. "Bones and Joints: The Effects of Cannabinoids on the Skeleton." Journal of Clinical Endocrinology & Metabolism 104, no. 10 (2019): 4683–94. http://dx.doi.org/10.1210/jc.2019-00665.

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Abstract Context The endocannabinoid system uses tissue-specific lipid ligands and G protein‒coupled transmembrane receptors to regulate neurologic, metabolic, and immune responses. Recent studies demonstrate that the endocannabinoid system influences bone metabolism. With the increasing use of endocannabinoid mimetics (e.g., tetrahydrocannabinol and cannabidiol), the involvement of endocannabinoids in bone growth and remodeling has become clinically relevant. Evidence Acquisition This literature review is based on a search of PubMed and Google Scholar databases as of June 2019 for all English

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Shirke, Sarika S., Sanket R. Jadhav, and Aarti G. Jagtap. "Methanolic Extract of Cuminum cyminum Inhibits Ovariectomy-Induced Bone Loss in Rats." Experimental Biology and Medicine 233, no. 11 (2008): 1403–10. http://dx.doi.org/10.3181/0803-rm-93.

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Several animal and clinical studies have shown that phytoestrogens, plant-derived estrogenic compounds, can be useful in treating postmenopausal osteoporosis. Phytoestrogens and phytoestrogen-containing plants are currently under active investigation for their role in estrogen-related disorders. The present study deals with anti-osteoporotic evaluation of phytoestrogen-rich plant Cuminum cyminum, commonly known as cumin. Adult Sprague-Dawley rats were bilaterally ovariectomized (OVX) and randomly assigned to 3 groups (10 rats/group). Additional 10 animals were sham operated. OVX and sham contr

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Dordzhieva, Tsagana V., та Lyubov A. Bembeeva. "Кости животных из позднесарматских погребений курганной группы «Кермен Толга»". Oriental Studies 14, № 2 (2021): 291–300. http://dx.doi.org/10.22162/2619-0990-2021-54-2-291-300.

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Introduction. The article introduces results of studies of animal bones excavated by the archaeological expedition of Kalmyk Research Institute of History, Philology and Economics (with E. V. Tsutskin as leading scientist) from Late Sarmatian burials within the Kermen Tolga Mound Group in the Sarpa Lowlands in 1979. Goals. The paper provides detailed descriptions of the animal bone remains, identifies their species composition, enumerates and compares the samples. Results. The study shows all the investigated Late Sarmatian burials of the Kermen Tolga Mound Group contained bone remains of only

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Rask, K. A. "Etruscan Animal Bones and Their Implications for Sacrificial Studies." History of Religions 53, no. 3 (2014): 269–312. http://dx.doi.org/10.1086/674242.

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Bonfá, Ana Lúcia de Oliveira, Eduardo Donato Alves, Víctor Fabrício, et al. "Simultaneous alterations in ovaries and bone as a result of Polycystic Ovary Syndrome." International Journal of Advances in Medical Biotechnology - IJAMB 3, no. 2 (2021): 2–14. http://dx.doi.org/10.52466/ijamb.v3i2.81.

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Polycystic ovary syndrome (PCOS) is one of the most widely recognized endocrine disorders affecting reproductive-age women. The etiopathogenesis and mechanisms of this syndrome remain unclear. Diagnosis requires two of the following: polycystic ovaries, oligo- or anovulation, and hyperandrogenism. Most women with PCOS display conditions such as metabolic abnormalities, diabetes, obesity, cardiovascular disease, and/or bone dysfunction. Considering the ethical limitations of human studies, animal and cell culture models that reflect some features of PCOS are important for investigation of this

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Erdogan, Özgür, Yakup Üstün, Ufuk Tatli, Ibrahim Damlar, and Kenan Daglıoglu. "A Pig Model for the Histomorphometric Evaluation of Hard Tissue Around Dental Implants." Journal of Oral Implantology 39, no. 5 (2013): 551–57. http://dx.doi.org/10.1563/aaid-joi-d-11-00009.

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This study aimed to evaluate the frontal bone of Swiss Domestic pigs as an animal model for the histologic-histomorphometric examination of bony tissue around dental implants. We inserted SLA surface implants 4.1 mm in diameter and 10 mm in length into the frontal bones of 9 Swiss-Domestic pigs. Histologic and histomorphometric studies were conducted on the undecalcified sections. Histologic examinations showed that the specimens contain a sufficient amount of bone to provide homogenous bone coverage for standard diameter dental implant placement. The mean bone to implant contact was 61.9% ± 8

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Braun, David R., Michael Pante, and William Archer. "Cut marks on bone surfaces: influences on variation in the form of traces of ancient behaviour." Interface Focus 6, no. 3 (2016): 20160006. http://dx.doi.org/10.1098/rsfs.2016.0006.

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Although we know that our lineage has been producing sharp-edged tools for over 2.6 Myr, our knowledge of what they were doing with these tools is far less complete. Studies of these sharp-edged stone tools show that they were most probably used as cutting implements. However, the only substantial evidence of this is the presence of cut marks on the bones of animals found in association with stone tools in ancient deposits. Numerous studies have aimed to quantify the frequency and placement of these marks. At present there is little consensus on the meaning of these marks and how the frequency

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Nesterova, M. S. "Bone as a Fuel: Studying the Properties Based on the Results of Experimental Observations." Vestnik NSU. Series: History and Philology 22, no. 3 (2023): 24–35. http://dx.doi.org/10.25205/1818-7919-2023-22-3-24-35.

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Purpose. Burnt animal bones are regularly found at archaeological sites of different eras and territories. One of the popular hypotheses suggests that they were used as fuel. The purpose of this work, based on experimental observations, is to determine the combustion temperature regime of bones different types in comparison with wood.Results. A series of nine experimental bonfires revealed the following advantages of bone as fuel: 1) increase in the maximum combustion temperature to 800–900 °C versus 600–700 °C in a fire with wood fuel only; 2) increase in the average range of combustion tempe

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Cardoso, Eduardo Burgarelli Mayrink, Sheila Canevese Rahal, Jeana Pereira da Silva, et al. "Imaging Studies of the Stifle Joint in Puma concolor (Linnaeus, 1771)." Veterinary Sciences 12, no. 2 (2025): 103. https://doi.org/10.3390/vetsci12020103.

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Although the stifle joint of wild felines shares several characteristics observed in domestic cats, other characteristics are specific to each species. This study aimed to evaluate the stifle joints of eight Puma concolor, including two young and six adults, through different imaging examinations. All stifles were assessed using radiographs and computed tomography (CT). Magnetic resonance imaging (MRI) was performed on the stifles of one animal using 7 Tesla equipment. In all imaging modalities, the four sesamoid bones were detected. Meniscal mineralization was identified in the stifles of thr

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Tajchman, Katarzyna, Aleksandra Ukalska-Jaruga, Marek Bogdaszewski, Monika Pecio, and Katarzyna Dziki-Michalska. "Accumulation of Toxic Elements in Bone and Bone Marrow of Deer Living in Various Ecosystems. A Case Study of Farmed and Wild-Living Deer." Animals 10, no. 11 (2020): 2151. http://dx.doi.org/10.3390/ani10112151.

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The aim of the study was to determine the concentrations of toxic elements accumulated in the bone marrow and bones (Cervus elaphus). The studies were carried out on two groups of young stags: farmed (n = 6) and wild (n = 9). Their body weights were measured and bone and bone marrow samples were collected. The concentrations of toxic elements were analyzed using the inductively coupled plasma mass spectrometry technique. The mean aluminum content in the bone marrow and bones of the farmed animals was significantly higher than in the wild group (p < 0.05). The mean concentration of arsenic,

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Marean, Curtis W., and Leanne Bertino. "Intrasite Spatial Analysis of Bone: Subtracting the Effect of Secondary Carnivore Consumers." American Antiquity 59, no. 4 (1994): 748–68. http://dx.doi.org/10.2307/282346.

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Animal bones discarded by people are commonly subject to disturbance by carnivores. These carnivores are present throughout the world and include wolves, coyotes, hyenas, and many others. This disturbance not only modifies and destroys bone, but also moves many of the bone fragments away from their original position of discard. Intrasite spatial analyses of bone that seek patterns meaningful to human behavior thus need to subtract the effect of carnivore disturbance. Experimental studies with spotted hyenas show that the position of a bone fragment on a limb bone, combined with bone surface mo

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Takiguchi, Tomoya, Hoa Thi Vu, and Yoshikazu Nishino. "Effects of Polychlorinated Dibenzo-p-dioxins, Polychlorinated Dibenzofurans, and Dioxin-like PCBs on Teeth and Bones in Animals and Humans." Toxics 11, no. 1 (2022): 7. http://dx.doi.org/10.3390/toxics11010007.

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Bone metabolism is regulated by endocrine systems, so people exposed to polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) may suffer adverse effects on bones and teeth. We reviewed previous publications in which effects of PCDD/Fs and dioxin-like polychlorinated biphenyls on the teeth and bones of animals and humans were found. The aim was to identify future research directions, particularly for epidemiological studies of populations exposed to PCDD/Fs in the environment. Exposure of fetuses to PCDD/Fs may affect odontogenesis, particularly enamel formation, but the effects of PCDD

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Ibrahim, Jamal, Vlad Brumfeld, Yoseph Addadi, Sarah Rubin, Steve Weiner, and Elisabetta Boaretto. "The petrous bone contains high concentrations of osteocytes: One possible reason why ancient DNA is better preserved in this bone." PLOS ONE 17, no. 10 (2022): e0269348. http://dx.doi.org/10.1371/journal.pone.0269348.

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The characterization of ancient DNA in fossil bones is providing invaluable information on the genetics of past human and other animal populations. These studies have been aided enormously by the discovery that ancient DNA is relatively well preserved in the petrous bone compared to most other bones. The reasons for this better preservation are however not well understood. Here we examine the hypothesis that one reason for better DNA preservation in the petrous bone is that fresh petrous bone contains more DNA than other bones. We therefore determined the concentrations of osteocyte cells occl

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Zambrano M., Lilibeth A., David Kilroy, Arun Kumar, Michael D. Gilchrist, and Aisling Ní Annaidh. "The presence of Wormian bones increases the fracture resistance of equine cranial bone." PLOS ONE 16, no. 4 (2021): e0249451. http://dx.doi.org/10.1371/journal.pone.0249451.

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Wormian (intrasutural) bones are small, irregular bones, that are found in the cranial sutures of the skull. The occurrence of Wormian bones in human skulls has been well documented but few studies have detected the presence of such bones in domestic animals. Although some research has linked the presence of Wormian bones to bone pathology, its anatomical significance in healthy individuals is not known. To the best of our knowledge, no previous study has examined the biomechanical features of Wormian bone. This study uses microCT imaging of the parietal bone region to determine the frequency

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Korolev, A., M. Kulkova M, V. Platonov, N. Roslyakova, A. Shalapinin, and Y. E. Yanish. "Archaeological Materials of Eneolithic Settlements in Forest-Steppe Zone of the Volga Region: A Source for Diet and Chronology." Radiocarbon 60, no. 5 (2018): 1587–96. http://dx.doi.org/10.1017/rdc.2018.114.

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ABSTRACTThe study the diet of Eneolithic populations is of great interest to archaeologists. However, the studies undertaken in the steppe and forest-steppe zones of Volga region in Russia have left many issues unsolved. Data collected recently through the comprehensive studies of Lebyazhinka VI settlement enable us to change this situation. Of particular importance at this settlement site is good preservation of animal bones, bone fishing tools, and ceramics of the same type with food crusts and connected to a large house pit. For the first time in this geographical area, bones of domestic an

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Chukwuemeke U, Wisdom, Ruth Oghenerukevwe Eyankware U, and Michael Chika Egwunyenga. "INVESTIGATION OF THE POTENTIAL OF WASTE BONES AS A CATALYST IN BIOFUEL PRODUCTION." Journal of Wastes and Biomass Management 5, no. 1 (2023): 15–21. http://dx.doi.org/10.26480/jwbm.01.2023.15.21.

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It has recently come to light that inappropriate waste management (particularly of animal bones) is a major contributor to environmental degradation on a global scale. Instead, it would be extremely beneficial to the economy if the bioeconomy civilization could find novel applications for these discards. Biodiesel’s output can be put to good use as a heterogeneous catalyst in the effective recycling of animal bone. Ca-based catalysts produced from discarded bones, have been extensively studied in the transesterification reaction due to their high catalytic activity and abundant feedstock. Calc

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Bonnet, N., C. L. Benhamou, H. Beaupied, et al. "Doping dose of salbutamol and exercise: deleterious effect on cancellous and cortical bones in adult rats." Journal of Applied Physiology 102, no. 4 (2007): 1502–9. http://dx.doi.org/10.1152/japplphysiol.00815.2006.

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Animal studies suggest that bone remodeling is under β-adrenergic control via the sympathetic nervous system. To our knowledge, the impact of β-agonist substances, at doping doses, has not been studied in adult rats. The purpose of this study was to examine the effects of salbutamol injections with or without treadmill exercise on trabecular and cortical bone in adult rats. Adult (36 wk of age) female Wistar rats ( n = 56) were treated with salbutamol (3 mg·kg−1·day−1 sc, 5 days/wk) or vehicle (sham) with or without subsequent treadmill exercise (13 m/min, 60 min/day, 5 days/wk) for 10 wk. Tib

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Jean, G., J. K. Roush, R. M. DeBowes, E. M. Gaughan, and J. Kirpensteijn. "Holding Power of Orthopaedic Screws in Metacarpal and Metatarsal Bones of Young Calves." Veterinary and Comparative Orthopaedics and Traumatology 05, no. 03 (1992): 100–103. http://dx.doi.org/10.1055/s-0038-1633077.

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SummaryThe holding power and holding power per mm bone width of 4.5 mm and 5.5 mm cortical and 6.5 mm cancellous orthopaedic screws were obtained by tensile load-to-failure studies in excised metacarpal and metatarsal bones of young female Holstein calves. Holding power and holding power per mm bone width of 6.5 mm orthopaedic screws were significantly greater than those of 4.5 and 5.5 mm orthopaedic screws in the diaphysis and metaphysis. Significant differences were not detected between holding power and holding power per mm bone width of 4.5 and 5.5 mm orthopaedic screws. The holding power

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Riquelme Cantal, José Antonio, Juan Manuel Garrido Anguita, and Adrián Ruiz Expósito. "Determinación de la edad del ganado vacuno en restos óseos arqueológicos de acuerdo con la fusión de los huesos largos en el sur de la península Ibérica. Algunas puntualizaciones." Arqueología y Territorio Medieval 32 (February 4, 2025): e9269. https://doi.org/10.17561/aytm.v32.9269.

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Currently, osteometric studies of archaeological faunal bone remains provide essential information for understanding the economy and beliefs of past societies. This, data such as the height at the withers, weight, or the age at death of animals allow us to reflect on issues related to meat consumption, secondary products (milk, hide, manure, etc.), or rituals associated to the corresponding cultures. In a high percentage of animal bone remains recovered, their state of preservation or fragmentation prevents us from obtaining a comprehensive view, which may lead us to errors. The exceptional di

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Farris, Michael K., Corbin A. Helis, Ryan T. Hughes, et al. "Bench to Bedside: Animal Models of Radiation Induced Musculoskeletal Toxicity." Cancers 12, no. 2 (2020): 427. http://dx.doi.org/10.3390/cancers12020427.

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Ionizing radiation is a critical aspect of current cancer therapy. While classically mature bone was thought to be relatively radio-resistant, more recent data have shown this to not be the case. Radiation therapy (RT)-induced bone loss leading to fracture is a source of substantial morbidity. The mechanisms of RT likely involve multiple pathways, including changes in angiogenesis and bone vasculature, osteoblast damage/suppression, and increased osteoclast activity. The majority of bone loss appears to occur rapidly after exposure to ionizing RT, with significant changes in cortical thickness

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Jannat, Nure, R. Islam, and N. Sultana. "Preparing and Presenting a Pigeon Skeleton for Gross Anatomical Study Using Boiling Maceration Method: A Quick and Effective Method." American Journal of Life Science and Innovation 2, no. 1 (2023): 26–32. http://dx.doi.org/10.54536/ajlsi.v2i1.1269.

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The study’s main objective was to prepare and display the pigeon skeleton using a practical and effective approach. Two matured domestic pigeons (Columba livia), aged 8 months old were purchased from local market, Gazipur sadar, Bangladesh for this purpose. This experiment was carried out in the department of Anatomy and Histology, Faculty of Veterinary Medicine and Animal Science in Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh, in January 2021. The birds were first killed by being injected with MgSO4 directly into the hearts. After dead, they were peeled usin

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Lewis, Danielle N., Abraham Nyska, Kennita Johnson, et al. "2-Butoxyethanol Female-Rat Model of Hemolysis and Disseminated Thrombosis: X-Ray Characterization of Osteonecrosis and Growth-Plate Suppression." Toxicologic Pathology 33, no. 2 (2005): 272–82. http://dx.doi.org/10.1080/019262390908362.

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We recently proposed a chemically induced rat model for human hemolytic disorders associated with thrombosis. The objective of the present investigation was to apply a noninvasive, high-magnification X-ray analysis, the Faxitron radiography system, to characterize the protracted bone damage associated with this 2-butoxyethanol model and to validate it by histopathology. Groups of female Fischer 344 rats were given 0, 250, or 300 mg of 2-butoxyethanol/kg body weight daily for 4 consecutive days. Groups were then sacrificed 2 hours or 26 days after the final treatment. The treated animals displa

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Ruszkowski, Jakub J., Anetta Hanć, Marcin Komosa, et al. "Profile of Selected Mineral Elements in Tibiotarsal Bone of the White-Tailed Sea Eagle in Its Natural Habitat." Animals 12, no. 20 (2022): 2744. http://dx.doi.org/10.3390/ani12202744.

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Mineral bone composition (dry matter, bones ash, P, Ca, Zn, Mn, Mg, and Cu) and Pb levels of tibiotarsi of seven White-Tailed Sea Eagles were assessed. Lead intoxication in different bird species including waterfowl and raptors is being studied worldwide. The bones were analyzed for Pb by mass spectrometry with excitation in inductively coupled plasma (ICP-MS Elan DRC II) and for bone composition by Atomic Emission Spectrometer (Agilent 4100 Microwave Plasma). Pb levels ranging from 3.54 µg/g to 74.6 µg/g DM suggest that some of the investigated birds might have been intoxicated by Pb. Results

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Potts, Richard. "Temporal span of bone accumulations at Olduvai Gorge and implications for early hominid foraging behavior." Paleobiology 12, no. 1 (1986): 25–31. http://dx.doi.org/10.1017/s0094837300002955.

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Bones of mammals exhibit progressive stages of weathering during their time of subaerial exposure. Consequently, the study of bone weathering in fossil assemblages may help to assess the period represented by an accumulation of bones. Stages of bone decomposition due to subaerial weathering have been identified in assemblages of fossil macromammals from Olduvai Gorge, Tanzania. A modern bone assemblage collected by spotted hyenas is used to devise a method for recognizing attritional accumulations of bones from weathering characteristics. This method, which involves study of long bone diaphyse

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Coutinho, P. S., N. M. Ocarino, M. B. Ferreira, et al. "Familial osteopetrosis in Agouti paca: report of nine cases." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 60, no. 6 (2008): 1454–60. http://dx.doi.org/10.1590/s0102-09352008000600022.

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Nine cases of familial osteopetrosis were studied in Agouti paca rodents maintained in captivity. Animals were distributed in three groups depending on the severity of their skeletal lesions. Based upon clinical, radiological, and microscopic findings, it was concluded that one animal had level I lesions, three animals had level II lesions, and five animals had level III osteopetrosis and osteonecrosis. Throughout the entire axial and appendicular skeleton, there was an increased amount of both trabecular and cortical bone tissue. All analyzed bones showed thickened cortex and reduced medullar

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Deltoro, J., and Ana M. López. "Allometric growth patterns of limb bones in rabbits." Animal Production 46, no. 3 (1988): 461–67. http://dx.doi.org/10.1017/s0003356100019073.

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ABSTRACTRelative growth of length and thickness of femur, tibia, humerus and radius-ulna was studied using data from 320 rabbits from both sexes of two lines (New Zealand White and California). A cross-sectional design was used with slaughter points fixed at weekly intervals from 1 to 20 weeks of age. Carcass length was chosen as independent variable and two models were fitted to the data. Model 1 assumed the existence of one allometric change at some moment of the post-natal development and model 2 of a continuous change of the allometric coefficient throughout the experimental period.Most of

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Krylasova, N. B., and P. A. Kosintsev. "NATURE-MADE CHARMS OF MAMMAL BONE IN THE MEDIEVAL PERM CIS-URALS." Вестник Пермского университета. История, no. 1(52) (2021): 81–93. http://dx.doi.org/10.17072/2219-3111-2021-1-81-93.

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Mammal bone charms held a special place in the culture of the Finno-Ugrian people of the Perm Cis-Urals. Apart from the drilled hole, these bones were not treated in any way. Analysis of charms unearthed in medieval settlements and burial sites showed that particular parts of the mammal’s skeleton were used – mandibles of fur animals (marten, beaver, fox) and teeth, as well as talus bones of beavers and small cattle. Other bones, such as bears’ ungual phalanxes, otters’ penile bones, martens’ and hares’ lower extremities and reindeer’s prongs, were less common. As for the teeth, they comprise

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Piotrowska, Katarzyna, and Maciej Tarnowski. "Bone Marrow Adipocytes—Role in Physiology and Various Nutritional Conditions in Human and Animal Models." Nutrients 13, no. 5 (2021): 1412. http://dx.doi.org/10.3390/nu13051412.

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In recent years, adipose tissue has attracted a lot of attention. It is not only an energy reservoir but also plays important immune, paracrine and endocrine roles. BMAT (bone marrow adipose tissue) is a heterogeneous tissue, found mostly in the medullary canal of the long bones (tibia, femur and humerus), in the vertebrae and iliac crest. Adipogenesis in bone marrow cavities is a consequence of ageing or may accompany pathologies like diabetes mellitus type 1 (T1DM), T2DM, anorexia nervosa, oestrogen and growth hormone deficiencies or impaired haematopoiesis and osteoporosis. This paper focus

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Weiser, Michael, Lindsay Stoy, Valerie Lallo, Sriram Balasubramanian, and Anita Singh. "The Efficacy of Body-Weight Supported Treadmill Training and Neurotrophin-Releasing Scaffold in Minimizing Bone Loss Following Spinal Cord Injury." Bioengineering 11, no. 8 (2024): 819. http://dx.doi.org/10.3390/bioengineering11080819.

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Spinal cord injury (SCI) can lead to significant bone loss below the level of the lesion increasing the risk of fracture and increased morbidity. Body-weight-supported treadmill training (BWSTT) and transplantation strategies using neurotrophins have been shown to improve motor function after SCI. While rehabilitation training including BWSTT has also been effective in reducing bone loss post-SCI, the effects of transplantation therapies in bone restoration are not fully understood. Furthermore, the effects of a combinational treatment strategy on bone post-SCI also remain unknown. The aim of

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Trbojević Vukičević, Tajana, Kim Korpes, Martina Đuras, Zoran Vrbanac, Ana Javor, and Magdalena Kolenc. "Paleopathological Changes in Animal Bones from Croatian Archaeological Sites from Prehistory to New Modern Period." Veterinary Sciences 10, no. 5 (2023): 361. http://dx.doi.org/10.3390/vetsci10050361.

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A special part of archaeology, so-called archaeozoopathology or veterinary paleopathology is dedicated to studies of paleopathological changes in animal remains and contributes to the knowledge of ancient veterinary medicine and the history of diseases. In our study, we analyze paleopathological changes determined by gross observation and diagnostic imaging in the animal material originating from eight archaeological sites in Croatia. A standard archaeozoological analysis was carried out and specimens with visually detected macrostructural changes were radiographed. In total, 50 animal remains

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Yee, Michelle Min Fang, Kok-Yong Chin, Soelaiman Ima-Nirwana, and Sok Kuan Wong. "Vitamin A and Bone Health: A Review on Current Evidence." Molecules 26, no. 6 (2021): 1757. http://dx.doi.org/10.3390/molecules26061757.

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Vitamin A is a fat-soluble micronutrient essential for growth, immunity, and good vision. The preformed retinol is commonly found in food of animal origin whereas provitamin A is derived from food of plant origin. This review summarises the current evidence from animal, human and cell-culture studies on the effects of vitamin A towards bone health. Animal studies showed that the negative effects of retinol on the skeleton were observed at higher concentrations, especially on the cortical bone. In humans, the direct relationship between vitamin A and poor bone health was more pronounced in indi

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Kędzia, Gabriela, Martyna Woźniak, Włodzimierz Samborski, and Bogna Grygiel-Górniak. "Impact of Dietary Protein on Osteoporosis Development." Nutrients 15, no. 21 (2023): 4581. http://dx.doi.org/10.3390/nu15214581.

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Osteoporosis is a frequent yet unsolved health problem among older people. The influence of dietary protein still raises many questions regarding its quality and quantity in the context of bone health. The aim of this manuscript is to review the latest evidence on plant and animal protein influences on bone health in various groups of patients. The review is based on original studies, meta-analyses, randomized controlled trials, and prospective cohort studies published in PubMed and Cochrane databases during the last five years. Combining plant and animal protein with physical activity has the

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MUTLU, ZIHNI, ALEKSANDER CHRÓSZCZ, DIDAR AYDIN KAYA, et al. "Correlation between long-bone dimensions and body mass in cats." Medycyna Weterynaryjna 81, no. 02 (2025): 6950–2025. http://dx.doi.org/10.21521/mw.6950.

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Body mass significantly influences morphology in both humans and animals. The relations between the body mass and osteometric measurements of the skeleton can show adaptive changes in the animal skeleton due to body mass changes. This relationship had previously been analysed in dogs. The lack of such studies in cats encouraged us to investigate this topic. Radiogrammetric measurements were performed in live animals of both sexes (16 females and 20 males) in both dorsopalmar/dorsoplantar and mediolateral projections Morphometric measurements were performed for almost all long bones, e.g. the h

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Lipreri, M. V., A. Pasquarelli, D. Scelfo, N. Baldini, and S. Avnet. "DEVELOPMENT OF A BONE-ON-A-CHIP MICROFLUIDIC DEVICE AS A MODEL OF OSTEOPOROSIS." Orthopaedic Proceedings 106-B, SUPP_1 (2024): 16. http://dx.doi.org/10.1302/1358-992x.2024.1.016.

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Osteoporosis is a progressive, chronic disease of bone metabolism, characterized by decreased bone mass and mineral density, predisposing individuals to an increased risk of fractures. The use of animal models, which is the gold standard for the screening of anti-osteoporosis drugs, raises numerous ethical concerns and is highly debated because the composition and structure of animal bones is very different from human bones. In addition, there is currently a poor translation of pre-clinical efficacy in animal models to human trials, meaning that there is a need for an alternative method of scr

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Andrássy, László, Gyula Maros, István János Kovács, et al. "Application of Laser-based geological techniques to bone research: Calcium oxide distribution analyses of animal bones." Orvosi Hetilap 155, no. 45 (2014): 1783–93. http://dx.doi.org/10.1556/oh.2014.30010.

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The structural similarities between the inorganic component of bone tissue and geological formations make it possible that mathematic models may be used to determine weight percentage composition of different mineral element oxides constituting the inorganic component of bone tissue. The determined weight percentage composition can be verified with the determination of element oxide concentration values by laser induced plasma spectroscopy and inductively coupled plasma optical emission spectrometry. It can be concluded from calculated weight percentage composition of the inorganic component o

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Smirina, Ella, and Natalia Ananjeva. "Growth layers in bones and acrodont teeth of the agamid lizard Laudakia stoliczkana (Blanford, 1875) (Agamidae, Sauria)." Amphibia-Reptilia 28, no. 2 (2007): 193–204. http://dx.doi.org/10.1163/156853807780202512.

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AbstractGrowth layers in different tubular bones, in dental bone and in tooth dentine of L. stoliczkana were examined to estimate their suitability for the study of its age and growth. All bones studied have growth layers recording annual seasonal patterns of growth. Their pattern is identical in all bones studied. Resting lines, or Lines of Arrested Growth (LAGs) corresponding to the two first hibernations are subjected to resorption in the massive elongate tubular bones (femur and tibia) whereas in the more slender fibula the rate of resorption is lower. In the phalanx even the first formed

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Fan, Chiaming, Kristen R. Georgiou, Tristan J. King, and Cory J. Xian. "Methotrexate Toxicity in Growing Long Bones of Young Rats: A Model for Studying Cancer Chemotherapy-Induced Bone Growth Defects in Children." Journal of Biomedicine and Biotechnology 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/903097.

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The advancement and intensive use of chemotherapy in treating childhood cancers has led to a growing population of young cancer survivors who face increased bone health risks. However, the underlying mechanisms for chemotherapy-induced skeletal defects remain largely unclear. Methotrexate (MTX), the most commonly used antimetabolite in paediatric cancer treatment, is known to cause bone growth defects in children undergoing chemotherapy. Animal studies not only have confirmed the clinical observations but also have increased our understanding of the mechanisms underlying chemotherapy-induced s

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Wild, Michael de, Simon Zimmermann, Falko Schlottig, et al. "Immediate stabilization of pedicle screws." Current Directions in Biomedical Engineering 9, no. 1 (2023): 13–16. http://dx.doi.org/10.1515/cdbme-2023-1004.

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Abstract This study was designed as proof of principle and safety test of the novel technique, the Immediate Stabilization System (ISS). The technique is designed to immediately stabilize polymer-augmented pedicle screws (PAS) in deficient bone and avoid complications of loosening pedicle screws at the bone-screw interface, especially in osteoporotic patients. A polymer sleeve was designed as augmentation to improve screw anchorage after drilling the screw hole. By applying ultrasonic energy, the polymeric tube was molded into the pores of the host bone forming a strong and uniform bond with t

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Wilczyński, Jarosław, Piotr Wojtal, and Jiří Svoboda. "Pavlovian hunters on the margin – archaeozoological analysis of the animal remains discovered at the Pavlov II site (1966 – 67 excavations)." Fossil Imprint 73, no. 3-4 (2017): 322–31. http://dx.doi.org/10.2478/if-2017-0018.

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Our archaeozoological studies concerns animal remains discovered during fieldworks led by B. Klíma in 1966 – 1967. The study does not include a few bone tools and personal ornaments made from animal teeth. There were analysed 968 remains of different animal species. Among the mammals, the most numerous are bones and teeth of mammoth, horse, wolf, and reindeer. Other taxa are less numerous, but we point out presence of cave lion bones. The quantity of animal remains discovered at Pavlov II is much lower in comparison with other Pavlovian sites from Pavlov-Dolní Věstonice area. The localization

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