Academic literature on the topic 'Animal testing'

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Journal articles on the topic "Animal testing"

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Sanjana, Rahul Mirge. "Animal Testing and Ethics." Animal Testing and Ethics 8, no. 12 (2023): 2. https://doi.org/10.5281/zenodo.10405259.

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Animal testing has been a contentious issue at the intersection of scientific research, medical advancement, and ethical considerations. This abstract explores the ethical dimensions surrounding animal testing, aiming to shed light on the ongoing debate and emphasize the importance of finding a balance between scientific progress and ethical responsibilities. The ethical considerations of animal testing encompass concerns about the welfare and rights of animals, prompting discussions on the necessity, justification, and humane treatment of animals in research settings. While animal testing has
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Fano, Alix. "Animal Testing." Journal of the Royal Society of Medicine 90, no. 12 (1997): 710. http://dx.doi.org/10.1177/014107689709001237.

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Anderson, Christopher. "Less animal testing." Nature 352, no. 6336 (1991): 557. http://dx.doi.org/10.1038/352557c0.

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HOGUE, CHERYL, and JEFF JOHNSON. "ANIMAL TESTING ALTERNATIVES." Chemical & Engineering News 85, no. 25 (2007): 12. http://dx.doi.org/10.1021/cen-v085n025.p012.

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Clotworthy, Margaret. "Testing animal tests." New Scientist 198, no. 2652 (2008): 16–17. http://dx.doi.org/10.1016/s0262-4079(08)60960-4.

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Stokes, WS. "Animals and the 3Rs in toxicology research and testing." Human & Experimental Toxicology 34, no. 12 (2015): 1297–303. http://dx.doi.org/10.1177/0960327115598410.

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Despite efforts to eliminate the use of animals in testing and the availability of many accepted alternative methods, animals are still widely used for toxicological research and testing. While research using in vitro and computational models has dramatically increased in recent years, such efforts have not yet measurably impacted animal use for regulatory testing and are not likely to do so for many years or even decades. Until regulatory authorities have accepted test methods that can totally replace animals and these are fully implemented, large numbers of animals will continue to be used a
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Verity, Erin E., Kathy Stewart, Kirsten Vandenberg, Chi Ong, and Steven Rockman. "Potency Testing of Venoms and Antivenoms in Embryonated Eggs: An Ethical Alternative to Animal Testing." Toxins 13, no. 4 (2021): 233. http://dx.doi.org/10.3390/toxins13040233.

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Venoms are complex mixtures of biologically active molecules that impact multiple physiological systems. Manufacture of antivenoms (AVs) therefore requires potency testing using in vivo models to ensure AV efficacy. As part of ongoing research to replace small animals as the standard model for AV potency testing, we developed an alternate in vivo method using the embryonated egg model (EEM). In this model, the survival of chicken embryos envenomated in ovo is determined prior to 50% gestation, when they are recognized as animals by animal welfare legislation. Embryos were found to be susceptib
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Hajar, Rachel. "Animal testing and medicine." Heart Views 12, no. 1 (2011): 42. http://dx.doi.org/10.4103/1995-705x.81548.

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Hajar, Rachel. "Alternative to animal testing." Heart Views 12, no. 1 (2011): 39. http://dx.doi.org/10.4103/1995-705x.81551.

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Farland, William H., and Vicki Vaughn-Dellarco. "Animal Testing and EPA." Science 270, no. 5244 (1995): 1907–9. http://dx.doi.org/10.1126/science.270.5244.1907.

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Dissertations / Theses on the topic "Animal testing"

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Skopp, Stacy. "Fertility Associated Antigen (FAA): Economics of Testing." Thesis, The University of Arizona, 2011. http://hdl.handle.net/10150/203498.

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Proteins in bull semen have been found that increase fertility, including the fertility-associated antigen (FAA). The uses of FAA-positive bulls have been found in previous studies to increase conception rates at least 16%. Increased fertility rates by FAA-positive bulls increased the number of pregnant cows early in the breeding seasonUsing historical data to compute an equation that can demonstrate buyers and producers in the Southwestern United States the benefits of using and testing for FAA-positive bulls over time. The cost for addition of a cassette to the BSE testing will be offset by
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García, Díaz María. "Drug delivery in photodynamic therapy: From pharmaceutics to animal testing." Doctoral thesis, Universitat Ramon Llull, 2012. http://hdl.handle.net/10803/81987.

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S'ha estudiat el desenvolupament de fotosensibilitzadors i la seva formulació en teràpia fotodinàmica. S'han caracteritzat les propietats fotofísiques dels fotosensibilitzadors porficènics. S'han proposat diferents estratègies tals com la introducció de grups carboxilat en la perifèria o ions de metalls pesants en el nucli, per millorar el disseny de nous fotosensibilitzadors basats en el macrocicle porficènic. Entre ells, el temocè (m-THPPo), el porficè anàleg a la temoporfina, mostra excel•lents propietats fotofísiques, fotoestabilitat i alta eficàcia fotodinàmica. A causa de la seva alta
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Vondran, Jodi C. "A two pan feeding trial with companion dogs: considerations for future testing." Thesis, Kansas State University, 2013. http://hdl.handle.net/2097/15891.

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Master of Science<br>Food Science<br>Edgar Chambers IV<br>Palatability of pet foods is judged by the use of animals in colonies. Pet food manufacturers would like to understand how palatable a food is compared to another food. This generally is accomplished by a two pan test where a pet has the opportunity to freely choose between two foods. Preference is evaluated through the use of an intake ratio, the ratio of the amount of test food consumed divided by the total amount of the foods consumed. Although this is easy to do in laboratories, another option would be to do such studies with animal
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Westerlaken, Michelle. "A New User Testing Methodology for Digitally Mediated Human-Animal Interaction." Thesis, Malmö högskola, Fakulteten för kultur och samhälle (KS), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-21688.

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This thesis evaluates a novel methodology for the user testing of digitally mediated human-animal interactions. The proposed method includes the structural analysis of video observations following a Grounded Theory approach. Complemented with more subjective human observations, this methodology aims to initiate a more informed iterative design and research process in which the animal’s experience with a playful artefact is analysed and reflected upon. The research involves the user testing of a prototype for an independently developed tablet game designed for cats and humans. With a focus on t
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George, Courtney M. "Medulloblastoma: New animal models, preclinical drug testing, and characterising immune infiltrates." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2022. https://ro.ecu.edu.au/theses/2575.

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Medulloblastoma is the most common malignant brain tumour in children. The current treatment for medulloblastoma consists of surgery, radiation, and chemotherapy. Although these therapies have their merits, the outcome for some patients, particularly those with MYC amplified tumours, is poor, and the damaging nature of these therapies results in morbidities that significantly impact on a patient’s quality of life. To improve outcome and reduce adverse side effects, several strategies have been employed, including expanding the repertoire of accurate disease models, the development of novel the
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Shand, Ray Ann. "Investigations of thrombus formation in an animal model of arterial thrombosis." Thesis, University of Leeds, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236715.

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Arduini, Emmanuele. "Development and testing of new iron chelating agents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ55036.pdf.

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Gregoire, Zach. "A strategic approach to reducing mycoplasma testing costs." Thesis, Kansas State University, 2018. http://hdl.handle.net/2097/38619.

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Master of Agribusiness<br>Department of Agricultural Economics<br>Vincent R. Amanor-Boadu<br>Mycoplasma; it is not a household name for many Americans or people around the world, but for those in the livestock industry, it has been a major concern. Mycoplasma, a member of the class Mollicutes, has had and continues to have a major impact on the cattle, swine and poultry industry, causing conditions such as arthritis, otitis media, reduced growth rate and reduced egg production (Journal of Veterinary Internal Medicine 2011) (Okwara 2016). This class of bacteria is unlike other classes, as def
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Rode, Frederik. "Pharmacological testing in the spared nerve injury model of neuropathic pain /." Cph. : The Danish University of Pharmaceutical Sciences, Department of Pharmacology, 2005. http://www.dfuni.dk/index.php/Frederik_Rode/1938/0/.

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Lee, Chun-kei, and 李鎮基. "Development of an in vivo animal model for testing of endodontic medicaments on pulp tissue." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31954182.

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Books on the topic "Animal testing"

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Judson, Karen. Animal testing. Marshall Cavendish Benchmark, 2005.

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Hester, R. E., and R. M. Harrison, eds. Alternatives To Animal Testing. Royal Society of Chemistry, 2006. http://dx.doi.org/10.1039/9781847552457.

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Reinhardt, Christoph A., ed. Alternatives to Animal Testing. Wiley-VCH Verlag GmbH, 1994. http://dx.doi.org/10.1002/9783527616053.

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Kojima, Hajime, Troy Seidle, and Horst Spielmann, eds. Alternatives to Animal Testing. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2447-5.

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Royal Society of Chemistry (Great Britain), ed. Alternatives to animal testing. Royal Society of Chemistry, 2006.

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Axel, Schmidt, and Weber Olaf F, eds. Animal testing in infectiology. Karger, 2001.

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Terp, Gail. The debate about animal testing. Focus Readers, 2018.

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Watson, Stephanie. Animal testing: Issues and ethics. The Rosen Pub. Group, 2009.

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Welsh, Heidi J. Animal testing and consumer products. Investor Responsibility Research Center, 1990.

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Great Britain. Parliament. House of Commons. European Scrutiny Committee. Animal testing and cosmetic products. Stationery Office, 2002.

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Book chapters on the topic "Animal testing"

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Dumitrescu, Adrian, and Evan Hilscher. "Animal Testing." In Algorithms and Computation. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-25591-5_24.

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Moretto, Johnny, Bruno Chauffert, and Florence Bouyer. "Animal Testing." In Metallointercalators. Springer Vienna, 2011. http://dx.doi.org/10.1007/978-3-211-99079-7_16.

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Chandrakar, Tilak Ram, and Ajay Biswas. "Animal DNA Testing." In Fundamentals of Forensic Biology. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-3161-3_23.

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Wordsworth, Anne M. "Animal Cognition and Animal Intelligence." In Law, Animals and Toxicity Testing. Routledge, 2024. http://dx.doi.org/10.4324/9781032646350-1.

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Abel, Ernest L. "Testing Animal Behavioral Teratogens." In Behavioral Teratogenesis and Behavioral Mutagenesis. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0735-8_7.

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Knudsen, J. D., and N. Frimodt-Moller. "Animal Models in Bacteriology." In Animal Testing in Infectiology. KARGER, 2001. http://dx.doi.org/10.1159/000060386.

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Gottstein, B. "Animal Models in Parasitology." In Animal Testing in Infectiology. KARGER, 2001. http://dx.doi.org/10.1159/000060387.

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Weber, O. F. "Animal Models in Virology." In Animal Testing in Infectiology. KARGER, 2001. http://dx.doi.org/10.1159/000060388.

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Kamei, K., and M. Miyaji. "Animal Models in Mycology." In Animal Testing in Infectiology. KARGER, 2001. http://dx.doi.org/10.1159/000060389.

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Rizou, Katerina. "Detection of animal allergens in foods." In Food Allergen Testing. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118519219.ch05.

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Conference papers on the topic "Animal testing"

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Forrest, Stephen, John Paul Sodusta, Brian Herbst, and Steven E. Meyer. "Pendulum Animal Impact Testing." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-13057.

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When vehicles collide with large animals, such as cattle, moose, elk or horses, the front seat occupants can be seriously or fatally injured; primarily due to roof deformation. In order to protect the front occupants in these accidents, it is necessary to understand the forces and energy involved in the interaction between the animal and the vehicle roof structure. The authors have developed a pendulum test incorporating an animal dummy to generate similar roof deformation to that experienced in real world animal impact accidents. The energy absorbed by the vehicle roof structure in the accide
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Vasiliev, S. A., I. N. Matveeva, and M. I. Kruglova. "Application of 3R principles in testing recombinant vaccines." In БИОТЕХНОЛОГИЯ: НАУЧНЫЕ ИССЛЕДОВАНИЯ И СВЯЗЬ С ПРОИЗВОДСТВОМ. Всероссийский научно-исследовательский и технологический институт биологической промышленности, 2024. https://doi.org/10.47804/978-5-89904-038-2-2024-293-299.

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The article discusses the main provisions and principles of the 3R concept, which regulates the main provisions and approaches to working with laboratory animals. The concept itself consists of 3 areas: Replacement of animals in the experiment with other models, reduction of the use of animal objects by optimizing experimental conditions and improvement of existing methods aimed at reducing pain and stress of laboratory animals during experiments. A number of provisions of the 3R concept are subject to criticism. Different stakeholders (for example, animal experimenters, representatives of ins
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Bartel, S., J. Domin, J. Karczewski, et al. "TESTING THE STRENGTH OF LASER-BONDED ANIMAL INTESTINES." In Engineering Mechanics 2020. Institute of Thermomechanics of the Czech Academy of Sciences, Prague, 2020. http://dx.doi.org/10.21495/5896-3-066.

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Farrell, Jai, Chris McCarthy, and Caslon Chua. "Towards Animal Computer Interaction Testing for Assistive Canine Training." In ACI'2020: Seventh International Conference on Animal-Computer Interaction. ACM, 2020. http://dx.doi.org/10.1145/3446002.3446061.

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Bierbach, David, Fritz Francisco, Juliane Lukas, et al. "Biomimetic robots promote the 3Rs Principle in animal testing." In The 2021 Conference on Artificial Life. MIT Press, 2021. http://dx.doi.org/10.1162/isal_a_00375.

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KOO, B. C. P., and D. Y. C. LEUNG. "EMISSION TESTING ON A BIODIESEL PRODUCED FROM WASTE ANIMAL FATS." In Proceedings of the Third Asia-Pacific Conference. WORLD SCIENTIFIC, 2000. http://dx.doi.org/10.1142/9789812791924_0043.

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Peipei, Deng, Zhao Lei, Lu Jiaming, et al. "Initial testing of singles processing unit for the small animal PET." In 2017 13th IEEE International Conference on Electronic Measurement & Instruments (ICEMI). IEEE, 2017. http://dx.doi.org/10.1109/icemi.2017.8265864.

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Morell, J., and J. Alberts. "Biocompatibility Testing of the Advanced Animal Habitat – Centrifuge Science Evaluation Unit." In International Conference On Environmental Systems. SAE International, 2004. http://dx.doi.org/10.4271/2004-01-2395.

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"Postmortem Diagnosis of Rabies in Animal Brain by Fluorescent Antibody Testing." In International Conference on Advances in Agricultural, Biological & Environmental Sciences. International Institute of Chemical, Biological & Environmental Engineering, 2015. http://dx.doi.org/10.15242/iicbe.c0715124.

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Bazaev, Nikolai A., Denis V. Federyakin, Evgeniy V. Streltsov, Anastasiya V. Baklanova, and Nikita M. Zhilo. "Scientific Aspects of Lab and Animal testing of Wearable Dialysis Equipment." In 2020 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (EIConRus). IEEE, 2020. http://dx.doi.org/10.1109/eiconrus49466.2020.9039179.

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Reports on the topic "Animal testing"

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Keithly, Janet S. Testing Experimental Compounds against Leishmaniasis in Laboratory Animal Model Systems. Defense Technical Information Center, 1988. http://dx.doi.org/10.21236/ada196657.

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Jorgensen, Shelly. Design and testing of microfabricated surgical tools for large animal probe insertion. Office of Scientific and Technical Information (OSTI), 2016. http://dx.doi.org/10.2172/1305826.

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Gallogly, Hilary. Comparative Testing of Hemostatic Dressing in a Large Animal Model (Sus Scorofa) with Severe hepatic Injuries. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada608134.

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Mittal, Rahul, Muskaan Sahwney, Alan Ho, Khemraj Hirani, and Joana Lemos. Exploring the Potential of Simulation Models as Alternatives to Animal Models in Drug Testing and Biomedical Research: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.11.0028.

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Shrestha, Tanuja, Mir A. Matin, Vishwas Chitale, and Samuel Thomas. Exploring the potential of deep learning for classifying camera trap data: A case study from Nepal - working paper. International Centre for Integrated Mountain Development (ICIMOD), 2023. http://dx.doi.org/10.53055/icimod.1016.

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Data from camera trap networks provide crucial information on various important aspects of wildlife presence, movement, and behaviour. However, manual processing of large volumes of images captured is time and resource intensive. This study explores three different approaches of deep learning methods to detect and classify images of key animal species collected from the ICIMOD Knowledge Park at Godavari, Nepal. It shows that transfer learning with ImageNet pretrained models (A1) can be used to detect animal species with minimal model training and testing. These methods when scaled up offer tre
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Cao, Siyang, Yihao Wei, Tiantian Qi, et al. Stem cell therapy for peripheral nerve injury: An up-to-date meta-analysis of 55 preclinical researches. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.10.0083.

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Review question / Objective: It has been the gold standard for decades to reconstruct a large peripheral nerve injury with a nerve autograft, and this remains true today as well. In addition to nerve autografts, biological conduits and vessels can also be applied. A fair amount of studies have examined the benefits of adding stem cells to the lumen of a nerve conduit. The aim of this meta-analysis was to summarize animal experiments related to the utilization of stem cells as a luminal additive when rebuilding a peripheral nerve injury using nerve grafts. Eligibility criteria: The inclusion cr
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Gottlieb, Yuval, Bradley Mullens, and Richard Stouthamer. investigation of the role of bacterial symbionts in regulating the biology and vector competence of Culicoides vectors of animal viruses. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7699865.bard.

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Symbiotic bacteria have been shown to influence host reproduction and defense against biotic and abiotic stressors, and this relates to possible development of a symbiont-based control strategy. This project was based on the hypothesis that symbionts have a significant impact on Culicoides fitness and vector competence for animal viruses. The original objectives in our proposal were: 1. Molecular identification and localization of the newly-discovered symbiotic bacteria within C. imicola and C. schultzei in Israel and C. sonorensis in California. 2. Determination of the prevalence of symbiotic
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Committee on Toxicology. New Approach Methodologies (NAMs) In Regulatory Risk Assessment Workshop Report 2020- Exploring Dose Response. Food Standards Agency, 2024. http://dx.doi.org/10.46756/sci.fsa.cha679.

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The UK Food Standards Agency (FSA) and the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) held an “Exploring Dose Response” workshop in a multidisciplinary setting inviting regulatory agencies, government bodies, academia and industry. The workshop provided a platform from which to address and enable expert discussions on the latest in silico prediction models, new approach methodologies (NAMs), physiologically based pharmacokinetics (PBPK), future methodologies, integrated approaches to testing and assessment (IATA) as well as methodology validation. U
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Poverenov, Elena, Tara McHugh, and Victor Rodov. Waste to Worth: Active antimicrobial and health-beneficial food coating from byproducts of mushroom industry. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7600015.bard.

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Background. In this proposal we suggest developing a common solution for three seemingly unrelated acute problems: (1) improving sustainability of fast-growing mushroom industry producing worldwide millions of tons of underutilized leftovers; (2) alleviating the epidemic of vitamin D deficiency adversely affecting the public health in both countries and in other regions; (3) reducing spoilage of perishable fruit and vegetable products leading to food wastage. Based on our previous experience we propose utilizing appropriately processed mushroom byproducts as a source of two valuable bioactive
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Shpigel, Nahum, Raul Barletta, Ilan Rosenshine, and Marcelo Chaffer. Identification and characterization of Mycobacterium paratuberculosis virulence genes expressed in vivo by negative selection. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7696510.bard.

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Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of a severe inflammatory bowel disease (IBD) in ruminants, known as Johne’s disease or paratuberculosis. Johne’s disease is considered to be one of the most serious diseases affecting dairy cattle both in Israel and worldwide. Heavy economic losses are incurred by dairy farmers due to the severe effect of subclinical infection on milk production, fertility, lower disease resistance and early culling. Its influence in the United States alone is staggering, causing an estimated loss of $1.5 billion to the agriculture indu
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