Academic literature on the topic 'Anion carrier'

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Journal articles on the topic "Anion carrier"

1

Tosolini, Massimo, Paolo Pengo, and Paolo Tecilla. "Biological Activity of Trans-Membrane Anion Carriers." Current Medicinal Chemistry 25, no. 30 (2018): 3560–76. http://dx.doi.org/10.2174/0929867325666180309113222.

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Natural and synthetic anionophores promote the trans-membrane transport of anions such as chloride and bicarbonate. This process may alter cellular homeostasis with possible effects on internal ions concentration and pH levels triggering several and diverse biological effects. In this article, an overview of the recent results on the study of aniontransporters, mainly acting with a carrier-type mechanism, is given with emphasis on the structure/activity relationship and on their biological activity as antibiotic and anticancer agents and in the development of new drugs for treating conditions
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2

Simchowitz, L., R. Ratzlaff, and P. De Weer. "Anion/anion exchange in human neutrophils." Journal of General Physiology 88, no. 2 (1986): 195–217. http://dx.doi.org/10.1085/jgp.88.2.195.

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Of the total one-way chloride fluxes (approximately 1.4 meq/liter cell water X min) in steady state human polymorphonuclear leukocytes bathed in 148 mM Cl media, approximately 70% behaves as self-exchange mediated by a nonselective anion carrier that is not inhibited by stilbene disulfonates. Five properties of this carrier-mediated exchange were investigated: substrate saturation is seen with respect to 36Cl influx as a function of the external Cl concentration [for normal-Cl cells, the apparent Km(Cl) is approximately 22 mM when Cl replaces para-amino-hippurate (PAH) and approximately 5 mM w
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3

Keihankhadiv, Shadi, and Dorota Neugebauer. "Synthesis and Characterization of Linear Copolymers Based on Pharmaceutically Functionalized Monomeric Choline Ionic Liquid for Delivery of p-Aminosalicylate." Pharmaceutics 15, no. 3 (2023): 860. http://dx.doi.org/10.3390/pharmaceutics15030860.

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Bioactive linear poly(ionic liquid)s (PIL) were designed as carriers in drug delivery systems (DDS). Their synthesis was based on a monomeric ionic liquid (MIL) with a relevant pharmaceutical anion to create therapeutically functionalized monomers, which further can be used in the controlled atom transfer radical polymerization (ATRP). The presence of chloride counterions in the quaternary ammonium groups of choline MIL, e.g., [2-(methacryloyloxy)ethyl]trimethyl-ammonium chloride (ChMACl), was stimulated to undergo the anion exchange with p-aminosalicylate sodium salt (NaPAS) as the source of
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4

Fortenberry, R. C. "Theoretical Electronic and Rovibrational Studies for Anions of Interest to the DIBs." Proceedings of the International Astronomical Union 9, S297 (2013): 344–48. http://dx.doi.org/10.1017/s1743921313016098.

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AbstractThe dipole-bound excited state of the methylene nitrile anion (CH2CN−) has been suggested as a candidate carrier for a diffuse interstellar band (DIB) at 803.8 nm. Its corresponding radical has been detected in the interstellar medium (ISM), making the existence for the anion possible. This work applies state-of-the-art ab initio methods such as coupled cluster theory to reproduce accurately the electronic excitations for CH2CN− and the similar methylene enolate anion, CH2CHO−. This same approach has been employed to indicate that 19 other anions may possess electronically excited stat
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5

Buttner, B., and D. Beyersmann. "Modification of the erythrocyte anion carrier by chromate." Xenobiotica 15, no. 8-9 (1985): 735–41. http://dx.doi.org/10.3109/00498258509047435.

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6

Pedersen, Peter L. "An introduction to the mitochondrial anion carrier family." Journal of Bioenergetics and Biomembranes 25, no. 5 (1993): 431–34. http://dx.doi.org/10.1007/bf01108400.

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7

Pritchard, J. B., and D. S. Miller. "Comparative insights into the mechanisms of renal organic anion and cation secretion." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 261, no. 6 (1991): R1329—R1340. http://dx.doi.org/10.1152/ajpregu.1991.261.6.r1329.

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Comparative models have played a major role in defining the mechanisms that enable vertebrate proximal tubules to transport organic anions and cations from the peritubular interstitium to the urine. The unique advantages of these models and their contributions to our understanding of organic anion and cation transport mechanisms are summarized here. Recent studies of the organic anion transport system suggest that transport is coupled to metabolic energy via indirect coupling to the sodium gradient. Organic anions enter the cell across the basolateral membrane in exchange for alpha-ketoglutara
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8

Restrepo, D., B. L. Cronise, R. B. Snyder, L. J. Spinelli, and P. A. Knauf. "Kinetics of DIDS inhibition of HL-60 cell anion exchange rules out ping-pong model with slippage." American Journal of Physiology-Cell Physiology 260, no. 3 (1991): C535—C544. http://dx.doi.org/10.1152/ajpcell.1991.260.3.c535.

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According to the ping-pong model of band 3-mediated anion exchange, the transport protein has a single transport site, which can exist in either an inward-facing or an outward-facing conformation. Anions bind to these unloaded forms of the carrier, and translocation takes place only when a suitable anion is bound to the transport site. In a previous paper [Am. J. Physiol. 257 (Cell Physiol. 26): C520-C527, 1989], we had shown that the substrate kinetics of Cl-Cl exchange in the promyelocytic HL-60 cell cannot be explained by this simple ping-pong model of anion exchange but is consistent with
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9

Elgavish, A., J. J. Wille, F. Rahemtulla, and L. Debro. "Carrier-mediated sulfate transport in human ureteral epithelial cells cultured in serum-free medium." American Journal of Physiology-Cell Physiology 261, no. 5 (1991): C916—C926. http://dx.doi.org/10.1152/ajpcell.1991.261.5.c916.

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Sulfate transport studies were carried out in secondary cultures of epithelial cells isolated from the human ureter. Results demonstrate the presence of carrier-mediated SO4(2-) transport as supported by three lines of evidence: 1) saturation kinetics, 2) substrate specificity, and 3) inhibition by the anion transport inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS). The DIDS-insensitive component of SO4(2-) transport was markedly lower than the DIDS-sensitive component and was not affected by changes in extracellular pH (pHo) or Cl- concentration. The mechanism of this DIDS-i
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10

Chesher, D. A., P. A. Christensen, and A. Hamnett. "Anion movement and carrier type in polypyrrole/dodecyl sulfate." Journal of the Chemical Society, Faraday Transactions 89, no. 2 (1993): 303. http://dx.doi.org/10.1039/ft9938900303.

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