Relevant bibliographies by topics / Antacids

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Academic literature on the topic 'Antacids'

Author: Grafiati
Published: 4 June 2021
Last updated: 31 July 2024

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Journal articles on the topic "Antacids"

1

Ramadan, Mai, and Saba Turk. "Assessment of the Acid Neutralizing Capacity and Other Properties of Antacid Formulations Marketed in the Gaza Strip." Israa University Journal for Applied Science 6, no. 2 (April 1, 2023): 97–110. http://dx.doi.org/10.52865/qchr1551.

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Background: Antacids are frequently used as over-the-counter (OTC) medications to reduce symptoms of dyspepsia and to neutralize stomach acidity. Evaluation of antacids efficacy depends on in vitro testing like acid neutralizing capacity (ANC) and acid neutralization potential (ANP). The purpose of this study was to examine ANC, ANP, and other characteristics of commercially available antacid formulations (both liquid and solid formulations) in the Gaza Strip. Methods: Both liquid (n=2) and solid (n=4) antacid formulations were acquired from the Gaza Strip’s central community pharmacies. Preliminary antacid test (PAT) was carried out to determine if the tested formulation is classified as antacid. The general monograph <301> in USP34/NF29 was used for the estimation of ANC, while ANP was investigated using Rossett Rice procedure. Both tests were conducted to evaluate the efficacy of antacid. In addition, cost effectiveness per formulation and statistical analysis test of data were calculated. Results: All formulations were classified as antacids because they all passed the PAT test (pH of antacid-HCl over 3.5). The ANC of antacids (n=6) varied from 8.74±0.37 to 29.14±0.84 mEq per minimum labeled dose (MLD). The ANC/MLD ratios for solid formulations were higher than those of liquid formulations. No statistically significant difference in ANC/MLD between the two groups was estimated (P˃.0.05). ANP test - the time duration during which an antacid formulation maintains pH above 3.5 - ranged from 43 to 90 minutes. According to this study liquids were inefficient in acid neutralization and expensive as a result. Conclusions: The ANC and ANP results indicated the better neutralizing efficacy and duration of solid antacids in comparison to liquids. A1 and A2 formulations– calcium and magnesium salt based solid antacids had the most appropriate properties in terms of efficacy, onset and duration of neutralizing activity. Antacids in the form of chewable tablets were the most cost-effective formulations. It is recommended to examine more batches of the same antacids and to add ANC data on the label of antacids.
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Sutphen, James L., Vivian L. Dillard, and Mary E. Pipan. "Antacid and Formula Effects on Gastric Acidity in Infants With Gastroesophageal Reflux." Pediatrics 78, no. 1 (July 1, 1986): 55–57. http://dx.doi.org/10.1542/peds.78.1.55.

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A variety of peptic diseases are treated with antacids. Antacid dose requirements for young children have not been extensively evaluated. Moreover, the effects of formula feedings on antacid requirements are also unknown. We have investigated the effects of antacids and formula feedings on gastric acidity in infants less than 1 year of age. Small formula feedings of 15 mL/kg per feeding significantly improve antacid buffering of 0.5 mL/kg per dose of standard magnesium-aluminum hydroxide antacids.
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Garg, Vandana, Prashant Narang, and Ritu Taneja. "Antacids revisited: review on contemporary facts and relevance for self-management." Journal of International Medical Research 50, no. 3 (March 2022): 030006052210864. http://dx.doi.org/10.1177/03000605221086457.

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Heartburn and acid regurgitation are the typical symptoms of gastroesophageal reflux. Despite the availability of several treatment options, antacids remain the mainstay treatment for gastroesophageal reflux-related symptoms based on their efficacy, safety, and over-the-counter availability. Antacids are generally recommended for adults and children at least 12 years old, and the FDA recommends antacids as the first-line treatment for heartburn in pregnancy. This narrative review summarizes the mechanism, features, and limitations related to different antacid ingredients and techniques available to study the acid neutralization and buffering capacity of antacid formulations. Using supporting clinical evidence for different antacid ingredients, it also discusses the importance of antacids as OTC medicines and first-line therapies for heartburn, particularly in the era of the COVID-19 pandemic, in which reliance on self-care has increased. The review will also assist pharmacists and other healthcare professionals in helping individuals with heartburn to make informed self-care decisions and educating them to ensure that antacids are used in an optimal, safe, and effective manner.
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DEB, SIDDHARTHA. "Antacid Poisoning." Pediatrics 86, no. 2 (August 1, 1990): 325. http://dx.doi.org/10.1542/peds.86.2.325.

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To the Editor.— Dr J. Brand and Dr F. Greer's discussion of a case of hypermagnesemia and intestinal perforation following antacid administration in a premature infant1 can be misleading to physicians who may need to use antacids for treating their patients. The patient in consideration was receiving 18 mL/kg/d of antacids. This is equivalent to more than a liter of antacids per day for an average adult weighing 60 kg. The management of bleeding of the upper gastrointestinal tract would include the use of H2 receptor blocking agents and usually 2 to 4 mL of antacids or more per kg per day to keep the gastric pH value above 5. Hence, the complications in the baby discussed are secondary to massive overdosage and toxicity of the antacids and to not following routine antacid administration.
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Boya, Dina, and Jwan Ahmed. "Comparison of Acid-neutralizing capacity of antacids in Erbil City." Zanco Journal of Medical Sciences 25, no. 2 (August 11, 2021): 586–90. http://dx.doi.org/10.15218/zjms.2021.023.

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Background and objective: Antacids are basic substances that can neutralize hydrochloric acid and reduce gastric acidity. They are over the counter drugs used to treat dyspepsia. The most commonly used antacids are sodium bicarbonate, magnesium hydroxide, aluminum hydroxide, and calcium carbonate. This study aimed to evaluate the effectiveness of antacids that are commonly used in Erbil city by finding their acid-neutralizing capacity. Methods: The method for acid-neutralizing capacity was adapted from pharmacopeia. The samples were prepared by dissolving the antacid in an excess amount of hydrochloric acid, then neutralizing the excess acid with sodium hydroxide solution by doing back titration. The number of milliequivalents that are neutralized by the antacid is the acid-neutralizing capacity of the antacid. Results: Rennie® chewable tablet showed the highest acid-neutralizing capacity, followed by AntacidAwa and Maalux® plus. The lowest acid-neutralizing capacity was for the suspensions Gaviscon® and Enoxon®. Conclusion: Acid-neutralizing capacity is an easy and quick method to evaluate the efficacy of antacids. Different combinations of salts and concentrations can affect the acid-neutralizing capacity of the antacid. The higher the neutralizing effect of the antacid, the more effective the antacid is. Keywords: Acid-neutralizing capacity; Antacid; pH; Dyspepsia; Erbil.
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Parakh, Rajendra Kumar, and Neelakanth S. Patil. "Anaesthetic antacids: a review of its pharmacological properties and therapeutic efficacy." International Journal of Research in Medical Sciences 6, no. 2 (January 24, 2018): 383. http://dx.doi.org/10.18203/2320-6012.ijrms20180005.

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Anaesthetic antacids, combination of antacids (Aluminium hydroxide, Magnesium hydroxide) with an anaesthetic (oxethazaine), is becoming a choice of physicians and is re-emerging across all types of GI disorders (esophagitis, peptic ulcer, duodenal ulcer, heartburn, gastritis, functional dyspepsia), despite the discovery of potent and efficacious acid suppressants like H2 receptor blockers and proton pump inhibitors (PPIs). The reason being that anaesthetic antacids increase the gastric pH and provide relief from pain for a longer period of duration at considerably a lower dosage. Furthermore, it significantly increases the duration between the time of medication and the peak pH as compared to antacid alone. Oxethazaine, an anaesthetic component, produces a reversible loss of sensation and provides a prompt and prolonged relief of pain, thereby broadening the therapeutic spectrum of antacids. Antacids vary widely in their in vitro acid neutralizing capacity (ANC), which measures the potency. Among marketed brands in India, Digecaine has shown the highest potency with maximum mean ANC value (28.84 mEq). The expert panel has recommended the inclusion of oxethazaine-antacid/alginate-antacid as complementary to the proton pump inhibitors in the management algorithm of gastroesophageal reflux disease. The present review summarizes the pharmacokinetic and pharmacodynamic of different components of anaesthetic antacids and its clinical use across different gastrointestinal indications, for generalists and specialists, based on existing evidences.
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Watts, D. W. "In Vitro Buffering Capacities of Proprietary Non-Particulate Antacids Available in New Zealand." Anaesthesia and Intensive Care 22, no. 2 (April 1994): 184–86. http://dx.doi.org/10.1177/0310057x9402200212.

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Four commercially available non-particulate antacid preparations were titrated against 1M hydrochloric acid to assess buffering capacity as compared to 30 ml 0.3M sodium citrate solution. All antacids were used in the manufacturers “unit dose”. All antacids tested demonstrated some in vitro buffering capacity, and “Eno” (Reckitt and Colman) had a buffering capacity similar to that of sodium citrate. The retail cost per unit dose was established for each proprietary antacid and for sodium citrate. It was concluded that while proprietary antacids are cheaper per dose than sodium citrate, preparations differ in their acid-neutralising capacity.
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Benjamin U Ebeshi, Samuel J Bunu, Hilda F Kpun, and Cynthia O Ezebube. "Analysis of gastrointestinal acid-neutralizing potency of some commercial antacid tablet formulations." GSC Biological and Pharmaceutical Sciences 19, no. 2 (May 30, 2022): 008–13. http://dx.doi.org/10.30574/gscbps.2022.19.2.0159.

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In dyspepsia, formulations known as antacids are regularly used to alleviate symptoms as quickly as possible. Gastric contents are acidic; therefore, antacids are usually weak bases with the potential to neutralize excess acid and raise gastric pH accordingly. Acid-neutralizing capacity is what determines the effectiveness of an antacid. Some antacid tablets formulation from different manufacturers were tested for their acid-neutralizing capacity and effectiveness for patients in this study. The South-East region of Nigeria had pharmacies vending antacids of different brands. To remove potential bias from the study, the brands were coded A-F. Labels on all samples indicated that they would expire more than one year from now. To determine each antacid tablet's acid-neutralizing capacity, the titrimetric method was used. In terms of acid-neutralizing capacity, brands D, A, B, C, F, and E showed the greatest acid-neutralizing capacity (8.2mEq/g), and brand E showed the lowest capacity (5.7 mEq/g). An analysis of the ANC of all the tablets found that they exceeded the FDA standard of >5mEq for antacids. An inexpensive, simple, and easy-to-use titrimetric method could be used routinely to monitor antacid tablet quality.
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Plotnikova, E. Y., and L. G. Vologzhanina. "Antacids and their role in treatment of digestive diseases in pregnant women." Herald of Pancreatic Club 47, no. 2 (April 29, 2020): 82–88. http://dx.doi.org/10.33149/vkp.2020.02.10.

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Antacids are drugs that can neutralize or buffer the hydrochloric acid of the stomach without affecting its production. History of the clinical use of antacids dates back several centuries. The article discusses the advantages and disadvantages of modern antacids, provides a classification of drugs of this group, considers the mechanisms of their action, explains the term “acid-neutralizing activity”, lists indications for the use of antacids and possible adverse effects of antacid therapy. The results of various foreign and domestic studies on the use of acid-suppressive drugs, including antacids, are presented. Currently, antacids continue to be used for the symptomatic treatment of certain acid-dependent diseases, including gastroesophageal reflux disease (GERD). Due to a number of physiological reasons, GERD often worries pregnant women, most often in the third trimester of pregnancy. The choice of acid-suppressing agents in pregnant women is extremely limited, because the possibility of prescribing any drugs in this category of patients is determined by the safety of the drug, its tolerability, and the absence of teratogenic effects. Features of the mechanism of action of antacids, their favorable pharmacological properties determine the possibility of using modern combined drugs of this group during pregnancy. Relieving heartburn in pregnant women through the use of non-absorbable combined antacids is supported by the FDA, the European guidelines for the treatment of GERD. The article lists antacid drugs registered in the pharmaceutical market, special attention is paid to drugs approved for use during pregnancy.
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Okhuelegbe, Eraga Sylvester, Idemili Nwachukwu Osita, and Iwuagwu Magnus Amara. "In vitro interaction between Zidovudine and some adsorptive antacids." Dhaka University Journal of Pharmaceutical Sciences 13, no. 1 (February 2, 2015): 1–6. http://dx.doi.org/10.3329/dujps.v13i1.21853.

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The in vitro interaction between zidovudine and three antacids and a commercial product was investigated. The extent of adsorption of zidovudine by the antacids, and the effects of the antacids on the disintegration time and dissolution of the drug from tablets were studied. Adsorption of the drug by the antacids followed the order; magnesium trisilicate > aluminium hydroxide > magnesium hydroxide. Retardation of dissolution amongst the antacids and commercial product was of the order; Jawasil® > magnesium trisilicate > aluminium hydroxide > magnesium hydroxide. Also, the degree of retardation of dissolution from the tablets increased as the amount of adsorbent increased. Co-administration of zidovudine and adsorptive antacid formulations should be avoided in clinical practice since it can lead to a decrease in the bioavailability of zidovudine, ultimately leading to therapeutic failure. DOI: http://dx.doi.org/10.3329/dujps.v13i1.21853 Dhaka Univ. J. Pharm. Sci. 13(1): 1-6, 2014 (June)
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Dissertations / Theses on the topic "Antacids"

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Wardlow, Peter William. "Interactions involving antacids and adsorbents." Thesis, Queen's University Belfast, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356902.

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Jorsäter-Blomgren, Kerstin B. "An epidemiological study of drug-induced acute pancreatitis utilizing a Swedish case-control network /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-620-4/.

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Thiab, S. H. H. "The development of analytical procedures for analysis of trace metals in pharmaceutical formulations and the speciation of arsenic in antacids." Thesis, Liverpool John Moores University, 2018. http://researchonline.ljmu.ac.uk/8776/.

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The reliability of data obtained from the existing United States Pharmacopeia (USP) method, USP <231> for elemental impurities (EI) have been questioned in the literature. New regulations regarding EI in pharmaceutical products were recently implemented on the 1st January 2018. The new regulations are USP <232>/<233> and the International Council for Harmonisation equivalent guidelines (ICH Q3D). The new regulations include the use of instrumentation such as inductively coupled plasma optical emission spectroscopy (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). The aim of this work was to develop, optimise and validate analytical methods for the determination of Class 1 and Class 2A elements, arsenic (As), cadmium (Cd), mercury (Hg),lead (Pb), cobalt (Co), nickel (Ni) and vanadium (V) simultaneously in pharmaceutical products in compliance with the new guidelines. The developed ICP-OES and ICP-MS methods were validated using the only available solid standard reference material (SRM) NIST 3280 Multivitamin/Multielement tablets. It was found that relying solely on spiked addition technique as suggested by USP<233> is inefficient as it may not reflect clearly the method’s accuracy particularly when the sample preparation involves the use of microwave (MW)-assisted acid digestion step, which is very common for pharmaceutical samples. Sample preparation was performed using a developed MW-assisted acid digestion method with reverse aqua regia. It was found that reaching a temperature of 210°C for sample’s digestion is necessary to get EI recoveries of greater than 95% and pre-digestion grinding was found to be beneficial to minimise variation in data and get relative standard deviation (RSD)of less than 5%. The validation results showed good linearity (R2>0.995) over a wide range with low limits of detection (LoDs) and limits of quantification (LoQs). The calculated LoQs in ng/mL are As (5.86, 1.149), Cd (0.87, 0.037), Hg (2.23, 1.701) Pd (4.73, 0.041), Co (1.58, 0.299), Ni (1.74, 0.159) and V (7.64, 0.485) for ICP-OES and ICP-MS incorporated with collision reaction cell (CCT) respectively. Twenty-four commercially available pharmaceutical products including analgesic tablets, cough remedies, flu powders and antacids were analysed. Four products contained Cd in concentrations exceeding the permitted daily exposure limit (PDE) of 5μg/day when the maximum dose is taken, and nine products exceeded the 5μg/day PDE of Pb. This is especially concerning for the paediatric products because children are more susceptible to EI adverse effects as for example, they can absorb up to 40-70% of ingested Pb. The antacids were found to contain As and although the levels quantified were below the PDE (15μg/day), a speciation method using an ion-pair reversed phase high performance liquid chromatography (HPLC)-ICP-MS was optimised and validated according to ICH Q2B guidelines as no information regarding what species are present in such products is available in the literature. Four arsenic species were selected, arsenite (AsIII), arsenate (AsV), monomethyl arsonate (MMA) and dimethyl arsenate (DMA). Calibrations with R2>0.995 for all four species in the range of 1 to 50 ng/L and % recoveries>95% with RSD<5% were obtained. Arsenic was extracted from the samples using MW assissted extraction with 0.3M phosphoric acid at 55°C for 10 miutes, 75°C for 10 minutes and 95°C for 1 hour. The species were stable after being exposed to the extraction procedure (spiked recoveries >95%). This method was able to extract 95% or more of arsenic for all products. The ion-pair reversed phase chromatography was performed using a mobile phase: 10mmol/L tetrabutylammonium, 20mmol/L potassium dihydrogen orthophosphate and 2% methanol at pH 6 with a C18 column. The speciation analysis results for all the antacids showed that approximately 50% of the extracted As was present as the most toxic AsIII form. The work demonstrates some of the potential issues with the new regulations and the availability of suitable solid SRM and seeks to provide workable solutions for the analysis.
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Washington, N. "In vitro and in vivo evaluation of antacid and anti-reflux formulations." Thesis, University of Nottingham, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376161.

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Schrader, Kathleen McBride 1951. "Preoperative nonparticulate antacid therapy: A comparison of Bicitra and Alka-Seltzer effervescent." Thesis, The University of Arizona, 1994. http://hdl.handle.net/10150/278414.

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Pulmonary damage resulting from aspiration of gastric contents has been reported to be related to the acidity of the aspirate. The purpose of this research was to evaluate if Alka-Seltzer Effervescent and/or Bicitra, ingested preoperatively, increased gastric pH >2.5 and if so, which of the two products sustained the increase for the greatest length of time. Twenty-nine subjects ingested either Alka-Seltzer Effervescent (n = 15) or Bicitra (n = 14) during the immediate preoperative period. Gastric pH was analyzed at 30 and 60 minutes post-ingestion via oro- or naso-gastric tube. Repeated measures Analysis of Variance demonstrated that both antacids elevated gastric pH >2.5 at 30 and 60 minutes post-ingestion. However, Alka-Seltzer Effervescent produced a statistically significant greater (p =.032) increase in gastric pH than Bicitra at both 30 and 60 minutes post-ingestion.
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Chen, Chih-Ming, and 陳志明. "The Prescription Patterns of Antacids in the Ambulatory Care of NHI." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/25231393401497995797.

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碩士
國立臺灣大學
衛生政策與管理研究所
92
Abstract This study was intended to explore the prescription patterns and the problem of prescriptions containing Antacids in Taiwan, the results of this study may serve as the references for the decision making in health policy. The study was based on the sampling set of NHI claimed database of ambulatory care in 2002 from National Health Research Institutes. The prescription patterns and problems of prescription containing antacids were analyzed among various patient、hospital and doctor characteristics . The main findings of this study are described as followings: In terms of prescription patterns, 31.97% of total prescriptions contained antacids. In total prescriptions contained antacids, 39.52% of prescriptions contained antacids is no ulcer in last three years. 13.05% of total prescriptions contained antacids is no ulcer in last three years and no combine NSAIDs Factors related to higher use of antacids included male, 0~20 years old, the general clinic department, the dermatology department. Based on the findings described above, it is suggested that the causes of prescribing problems and the impact of prescribing problems should be further explored in the future. Meanwhile, the health authorities should establish an effective drug utilization review system in order to decrease antacids Keywords: Antacids, Ulcer, Overuse,Drug interaction
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Liau, Shu-Han, and 廖書涵. "Knowledge, Self-efficacy and Literacy regarding Correct Antacids Use among Senior/Vocational High School Students in Taiwan." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/86536712520191713675.

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碩士
國立臺灣師範大學
健康促進與衛生教育學系
103
The purpose of this study was to explore students’ knowledge, self-efficacy and literacy regarding correct antacids use and to examine the related factors. A probability-proportionate-to-size sampling method was used. Twenty senior/vocational high schools were randomly selected in Taiwan. A total of 1,947 students completed the online self-administered questionnaire in 2014. The main findings were as follows. 1.Half of the students reported that they had stomachache, while 35% experienced gastric hyperacidity during the past year. About 20% of students ever used antacids, while more than 30% of students experienced stomachache due to academic stress, stay up late, spicy food, and irregular meals. More than 30% of students did not read drug labels when purchasing medicines. 2.More than 30% of students did not know that it is not necessary to take medicines with antacids, while antacids can also interfere with other medications. 3.Students tend to have middle-high level of self-efficacy and literacy regarding the correct antacids usage. 4.Multiple regression analysis showed that female students who read drug labels, had higher knowledge and higher self-efficacy of correct antacids usage were more likely to have higher medication literacy. It is suggested that schools implement correct medication use education and promote healthy lifestyle to enhance students' medication literacy and proper medication usage.
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Lin, Mei-Shu, and 林美淑. "In vitro Study on The Efficacies of Antacids and Their Effect on The Disintegration of Enteric Coated Tablets." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/72499464818534038893.

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碩士
國立臺灣大學
藥學研究所
84
The purpose of this study is to investigate the influence of antacids on the disintegration of enteric coated drugs. The antacids and enteric coated tablets are collected from National Taiwan University Hospital. The quality of the antacids, in terms of preliminary antacid test (PAT) and neutralizing capacity (ANC) , as well as the quality of the enteric coated tablets, in terms of disintegration time were tested according to USP XXIII. In addition, the buffering capacity of antacids was tested in simulated physiological gastric secretion. According to USP XXIII criteria,Obira gel,showing a pH below 3.5 in preliminary antacid test (PAT), should not be labeled as an antacid, and was excluded from further experiment. The influence of the antacids on the disintegration of enteric coated tablets was tested by the following methods : I、tested according to USP XXIII with modification by adding the antacid to simulated gastric juice in the proportion of clinical dose / physiological gastric volume; II、tested in the mixture of antacids and simulated gastric juice with constant stirring on a stirer; III、tested in a mixture of simulated gastric juice containing a dose of antacid, with constant input (1.8 ml/min) of fresh simulated gastric juice and drainage of an equal volume of the reaction mixture from the container. The results demonstrated that the enteric coating of Dulcolax and Ecotrin were tolerable to any of the antacids in the three methods, while that of Voren was the most labile to any of the antacids in method I and II. NaHCO3 and Fanta 20ml showed the most strong effects,causing disintegration of the five enteric coated tablets in method I. On the contrary, Nacid, either 1 or 2 tablets, did not influence the disintegration of the five enteric coated tablets in the three methods. CaCO3 and Fanta 10ml were moderate,causing disintegration of most tablets only in method
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Chin-HsiangHuang and 黃進祥. "Exploring the Factors of National Health Insurance Non-Payment of Antacids Utilization Outpatients - An Example of a Medical Center." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/90077129895110603109.

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碩士
國立成功大學
工業與資訊管理學系專班
100
In Taiwan, the traditional concept Western medicine hurts stomach is prevalent, and many people have the misconception all the time. When they go to see a doctor, they often do not ask if antacids are appropriate for the treatment but require doctors to prescribe antacids. In addition, many physicians also prefer to prescribe antacids to patients’ requirement, and this may make antacids overused. In the case, it may not only increase health-care spending and lead to the waste of health-care resources, but also cause side effects. Based on the establishment of the public proper usage of drugs and self-care concept and cherishing medical resources, the authorities concerned should call on people that antacids are not a panacea, and the proper usage of them is the most important. 　　What makes this case occur often? It may be Patients' factors or physicians' factors. Take a southern medical center as an example, where outpatient health care doesn't cover antacids medication. The researcher wants to learn more about whether patient-related characteristics and physician-related characteristics affect the antacids usage. The researcher hopes to provide the hospital the basis of the management of the antacids usage, and to help improve the quality of physicians' prescription of antacids. 　　This research adopts Aday and Andersen’s Behavior Model of Health Service Utilization as the main research framework. The underlying characteristics of the patients are divided into predisposing characteristics factors, enabling resources factors and need factors on the utilization of antacids, including: patients' gender, age and medical part of the burden, the number of disease diagnosis, the presence of significant injuries, chronic illnesses, and whether the occupational injuries and diseases. Then add the physician-related characteristics to investigate the effect of antacids usage, which includes physicians' sex and age. The utilization of antacids includes: drug costs, drug delivery, quantity and dosing days. 　　In the research, the researcher extracts the cases from the southern Taiwan’s medical center, the cases' dates from January 1st, 2010 to December 31st, 2010. For data consolidation, and the definition of variables, grouped by households. We uses SPSS to run descriptive and inferential statistics and then to analyze the relevant factors affecting its system of acid utilization. 　　The research confirmed that the condition of antacids utilization is affected by the predisposing characteristics factors, need factors and physician-related factors. Therefore, I suggest that the health authorities concerned and the case hospital managers should formulate and implement the right antacids advocacy, education and training, and management practices.
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Chung-Shiu, Wu, and 吳宗修. "The antacid effects of Chinese medicinal prescriptions." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/b2hgns.

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碩士
台北醫學院
生藥學研究所
86
Antacids are traditionally used for the treatment of peptic ulcer.In clinica l, Tonic Chinese Medicinal prescriptions are the drugs for invigorating the sp leen and stomach, usually used in the treatment of peptic ulcer by clinical Ch inese Medical doctor. In this study, We have utilized artificial stomach of Fo rdtran as a model system to quantitative analysis the water extracts of the in vigorating the spleen and stomach in the extracts of Traditional Chinese Medic ines, which include Si jun zi tang(四君子湯), Xiang sha liu jun zi tang(香砂六 君子湯), Shao-yao gan-cao tang(芍藥甘草湯), An zhong san(安中散), Ren shen yan g rong tang(人參養榮湯), Shen ling bai-zhu san(參苓白朮散), Wu ji san(五積散), and Si ni tang(四逆湯).The results are as following:1.The Antacid effect whic h was tested by Acid Neutralizing Capacity(ANC):Colloidal aluminum phosphate( 磷酸鋁乳漿) (2.16*0.03)、Sodium bicarbonate(碳酸氫鈉)(1.83*0.03)、Shen ling ba i-zhu san(參苓白朮散) (1.76*0.03)、Wu ji san(五積散)(1.72*0.09)、Ren shen yang rong tang(人參養榮湯)(1.65*0.10)、Si ni tang(四逆湯) (1.60*0.05)、Xiang sha l iu jun zi tang(香砂六君子湯) (1.58*0.06)、Si jun zi tang(四君子湯)(1.57*0.04) 、An zhong san(安中散)(1.53*0.03)、Shao-yao gan-cao tang(芍藥甘草湯)(1.53*0.02 )、water(水)(1.44*0.03).2.The duration of the acid neutralization(minutes): Co lloidal aluminum phosphate(磷酸鋁乳漿)(172*3)、Xiang sha liu jun zi tang(香砂 六君子湯)(137*3)、An zhong san(安中散)(130*5)、Shen ling bai-zhu san(參苓白朮 散) (127*5)、Ren shen yang rong tang(人參養榮湯)(124*6)、Si jun zi tang(四君子 湯)(123*24)、Sodium bicarbonate(碳酸氫鈉)(121*14)、Wu ji san(五積散)(117*2)、S i ni tang(四逆湯) (100*17)、Shao-yao gan-cao tang(芍藥甘草湯)(92*8)、water(水) (87*6). The results of these studies indicate that antacid effects play an important role in the gastric protective mechanisms of Traditional Chinese Med icines in invigorating the spleen and stomach. One of the end point of hospice movement is Taiwan in to create the Chinese model of hospice care for our peo ple. The trial of TCDT was our preliminary effort for this end point.274 sequ ential patients were included in this retrospective study. Questionnaire surve y for autonomy demonstrated that 173 out of 274 terminal cancer patients (63.1 %) were willing to take TCDT. The remaining 101 (36.9%) patients who did not take TDCT were assumed as the control group.The first five leading primary can cers include Lung CA (25.5%), Liver CA (12.4%),Colorectal CA(10.9%),Stomach CA (10.9%) and Cervical UT. CA (5.5%) comprised the major distribution of disease entity. TCDT is prescribed according to the priority of their problem lists w hich indicated pain (79.2%), weakness (69.0%), non-appetite(46.4%), fever(36.5 %), dyspnea (31.0%) and edema(31.0%). After admission, assessment and regular medication of palliative care were performed for 1 week. TCDT followed with ta ilored menu and served as dessert between meals for another 1 week. The result s were evaluated by Verbal Numerical Scale method. Main components of menu wer e composed of Tremella fuciformis, Paeonia Lactilora &Glycyrrhiza and other tr aditional medicine profounded with vital substance. As the results of evaluati on, 149(86.1%) patients shows their strong affinity to TCDT . Pain control was significantly favored in the test group. Those having Glycyrrhiza -Paeonia so up revealed pain relief(P<0.01). It is concluded that TCDT adjuvantly improves quality of life of the terminal cancer patients(P<0.001). In terms of practic al and clinical extension of TCDT , further prospective randomized study is ne cessary to be organized.
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Books on the topic "Antacids"

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Cramer, Tom. When do you need an antacid?: A burning question. [Rockville, MD] (5600 Fishers Lane, Rockville 20857): [Dept. of Health and Human Services, Public Health Service, Food and Drug Administration, Office of Public Affairs, 1993.

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Cramer, Tom. When do you need an antacid?: A burning question. [Rockville, MD.] (5600 Fishers Lane, Rockville 20857): [Dept. of Health and Human Services, Public Health Service, Food and Drug Administration, Office of Public Affairs, 1993.

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Arnold, Berstad, ed. Management of peptic ulcer disease and acid-related disorders: Clinical aspects of antacids in the 1990s : Bermuda, November 15-16, 1991. [New York]: Raven Press, 1992.

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Center for Drugs and Biologics (U.S.), ed. Compliance program reference: Otc drug monograph implementation (compliance program #7361.003). [Rockville, Md.]: Center for Drugs and Biologics, 1985.

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Kivistö, Kari T. Interactions in drug absorption: With special reference to antacids and resins. Turku: Turun yliopisto, 1991.

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Parker, Philip M., and James N. Parker. Antacids: A medical dictionary, bibliography, and annotated research guide to Internet references. San Diego, CA: Icon Health Publications, 2003.

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Baak, Lubbertus Cornelis. Ambulatroy intragastric pH-monitoring in the assessment of acid-reducing agents. [The Netherlands: s.n.], 1991.

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Ltd, Mintel International Group, ed. Bras and pants: Coffee ; edible oils ; organic and ethical foods ; houseplants and cut flowers ; laxatives and antacids. London: Mintel International, 1997.

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Bradley-Kennedy, Carole Ann. The impact of delisting over-the-counter antacids from the Ontario drug benefit formulary on prescription gastrointestinal ulcer and reflux therapy drug usage. Ottawa: National Library of Canada, 1996.

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Halter, F., ed. Therapeutische Möglichkeiten bei Erkrankungen des oberen Gastrointestinaltraktes: Antacida im Blickpunkt. Wiesbaden: Vieweg+Teubner Verlag, 1992. http://dx.doi.org/10.1007/978-3-663-05262-3.

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Book chapters on the topic "Antacids"

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Theisler, Charles. "Antacids." In Adjuvant Medical Care, 22. New York: CRC Press, 2022. http://dx.doi.org/10.1201/b22898-26.

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Berstad, A., K. Berstad, and R. Weberg. "Antacids and Helicobacter pylori." In Therapeutische Möglichkeiten bei Erkrankungen des oberen Gastrointestinaltraktes: Antacida im Blickpunkt, 72–81. Wiesbaden: Vieweg+Teubner Verlag, 1992. http://dx.doi.org/10.1007/978-3-663-05262-3_6.

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Sewing, K. F. "Dosage and tolerance of antacids." In Therapeutische Möglichkeiten bei Erkrankungen des oberen Gastrointestinaltraktes: Antacida im Blickpunkt, 22–29. Wiesbaden: Vieweg+Teubner Verlag, 1992. http://dx.doi.org/10.1007/978-3-663-05262-3_2.

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Vicari, F. "Can continuous administration of antacids be considered?" In Benign Lesions of the Esophagus and Cancer, 329–30. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73055-9_90.

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Gugler, R. "Interactions between antacids and other drug treatments." In Therapeutische Möglichkeiten bei Erkrankungen des oberen Gastrointestinaltraktes: Antacida im Blickpunkt, 30–41. Wiesbaden: Vieweg+Teubner Verlag, 1992. http://dx.doi.org/10.1007/978-3-663-05262-3_3.

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Güldütuna, S. "The adsorption of bile acids by antacids." In Therapeutische Möglichkeiten bei Erkrankungen des oberen Gastrointestinaltraktes: Antacida im Blickpunkt, 42–55. Wiesbaden: Vieweg+Teubner Verlag, 1992. http://dx.doi.org/10.1007/978-3-663-05262-3_4.

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Tarnawski, A., H. Gergely, and T. G. Douglass. "Mucosal protection and ulcer healing by antacids." In Therapeutische Möglichkeiten bei Erkrankungen des oberen Gastrointestinaltraktes: Antacida im Blickpunkt, 56–71. Wiesbaden: Vieweg+Teubner Verlag, 1992. http://dx.doi.org/10.1007/978-3-663-05262-3_5.

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Kandadai, Sunitha Kanchi, and Mark V. Boswell. "Antacids, Gastrointestinal Prokinetics, and Proton Pump Inhibitors." In Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care, 345–63. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-8948-1_21.

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Wienbeck, M., P. Korda, and W. Schmidbaur. "Gastro-esophageal reflux disease: How effective are antacids?" In Therapeutische Möglichkeiten bei Erkrankungen des oberen Gastrointestinaltraktes: Antacida im Blickpunkt, 82–94. Wiesbaden: Vieweg+Teubner Verlag, 1992. http://dx.doi.org/10.1007/978-3-663-05262-3_7.

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Papazian, A. "Is the use of antacids justified in biliary reflux?" In Benign Lesions of the Esophagus and Cancer, 244–47. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73055-9_64.

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Conference papers on the topic "Antacids"

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Gutiérrez Lorenzo, M., P. Ciudad Gutiérrez, M. Fernández Gonzalez, and P. del Valle Moreno. "5PSQ-111 Pharmaceutical intervention: avoiding interactions between antiretrovirals and vitamin supplements/antacids." In 26th EAHP Congress, Hospital pharmacists – changing roles in a changing world, 23–25 March 2022. British Medical Journal Publishing Group, 2022. http://dx.doi.org/10.1136/ejhpharm-2022-eahp.424.

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Huh, Jin-Young, and Jin Woo Song. "Antacid and patient survival in idiopathic pulmonary fibrosis." In ERS International Congress 2023 abstracts. European Respiratory Society, 2023. http://dx.doi.org/10.1183/13993003.congress-2023.pa3450.

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Koledova, E. S., and Yu M. Yukhin. "METAL BISMUTH PROCESSING TO OBTAIN THE COMPOUNDS FOR MEDICINE." In XVI INTERNATIONAL CONFERENCE "METALLURGY OF NON-FERROUS, RARE AND NOBLE METALS" named after corresponding member of the RAS Gennady Leonidovich PASHKOVA. Krasnoyarsk Science and Technology City Hall, 2023. http://dx.doi.org/10.47813/sfu.mnfrpm.2023.258-265.

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Bismuth is one of rare metals, its content in the Earth’s crust is 2·10-5 wt. %. The annual world consumption of bismuth is 17–21 thousand tons, and bismuth compounds account for about 77 % of this amount. Bismuth compounds applied in medicine relate to binding, coating and antacid agents (basic Bismuth subnitrate, basic Bismuth subsalicylate, Vicalin, Vicair, De-Nol, Pilorid, Xeroform, Dermatol) or antiluetic drugs (Biiochinolum, Bismoverolum).
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Iancu, Vasile Ion. "SPE-LC-MS/MS DETECTION OF PHARMACEUTICAL COMPOUNDS (GASTRIC ANTACIDES) IN WASTEWATER." In International Symposium "The Environment and the Industry". National Research and Development institute for Industrial Ecology, 2023. http://dx.doi.org/10.21698/simi.2023.ab33.

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Wang, Chen, Congpeng Zhang, and Xiao Tian. "Object detection method based on improved cascade R-CNN for antacid bacilli." In Third International Conference on Artificial Intelligence and Electromechanical Automation (AIEA 2022), edited by Shuangming Yang and Guanglei Wu. SPIE, 2022. http://dx.doi.org/10.1117/12.2647000.

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Massen, G., A. D. Morgan, P. M. George, and J. K. Quint. "Does Antacid Therapy in Idiopathic Pulmonary Fibrosis Patients Increase Risk of Pneumonia? An Observational Cohort Study." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5944.

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Abnet, Christian C., Neal D. Freedman, Albert Hollenbeck, and Arthur Schatzkin. "Abstract A131: Antacid use and risk of larynx cancer in the NIH‐AARP Diet and Health Study." In Abstracts: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Dec 6–9, 2009; Houston, TX. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1940-6207.prev-09-a131.

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Widi, Nurul, Retno Widyowati, Herra Studiawan, and Sukardiman. "In Vitro Evaluation of Antacid and Anti-flatulent Activity in Ethanolic Extract Syrup of Clove Leaves (Eugenia Caryophyllata Thunberg)." In Bromo Conference, Symposium on Natural Products and Biodiversity. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0008361102720276.

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Choi, Won-Il, Jihyeon Jeong, and Choong Won Lee. "Association between antacid proton pump inhibitors and histamine 2 receptor antagonists) and incidence of lung cancer: a population-based cohort analysis." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa1731.

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Roth, A., G. I. Barbash, H. I. Miller, G. Keren, S. Laniado, and U. Seligsohn. "BLEEDING COMPLICATIONS DURING RT-PA THROMBOLYSIS RELATED TO USE OF ANTI-INFLAMMATORY DRUGS PRIOR TO ACUTE MYOCARDIAL INFARCTION ADMISSION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642977.

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Of 57 patients with acute myocardial infarction (AMI) treated with rt-PA, we observed 2 major bleeding complications, both in patients who had been treated with anti-inflammatory drugs prior to admission. The thrombolytic protocol included: lOmg rt-PA in bolus and continuous infusion of 110 mg over 6 hr 5,000 iu heparin in bolus and continuous infusion of 25,000 iu/ 24hr, and aspirin 250 mg/24hr. The first patient, a 64 year old woman had been taking indomethacin 25 mg × 3 daily, during 3 weeks prior to the AMI. Rt-PA protocol was initiated with relief of chest pain and disappearance of ST elevation, but at 2 hr rt, sciatic pain developed. Treatment was continued accor ding to protocol in spite of the pain, but on the 3rd day hemoglobin decreased to 7.8%. Abdominal CT scan disclosed retroperitoneal hemorrhage. All anticoagulant medications were stopped, and 4 units of blood were transfused. The retro-peritoneal mass dissolved gradually. The second patient, a 68 year old male was treated by diclofenac 100 mg for 5 days prior to admission for AMI, and consequently aspirin was removed from the rt-PA protocol. However, 2 hr after completion of the 6 hr rt-PA infusion, gross hematuria and a “coffee ground” vomiting developed. Heparin infusion was discontinued and antacid treatment initiated, resulting in cessation of bleeding within a few hrs. In both patients the anticipated prolongation of APTT (heparin) and about 30% decrease in fibrinogen level were observed as the sole abnormality, and thus we related the bleeding episodes to the anti-aggregating effect of indomethacin and diclofenac respectively. We suggest that the use of anti-inflammatory drugs prior to administration of rt-PA protocol can be hazardous, and that special prudence (possibly protocol modification) is warranted.
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