Academic literature on the topic 'Anthelmintic drug'

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Journal articles on the topic "Anthelmintic drug"

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Dyary, Hiewa Othman. "Veterinary Anthelmintics and Anthelmintic Drug Resistance." Journal of Zankoy Sulaimani - Part A 18, no. 1 (2015): 191–206. http://dx.doi.org/10.17656/jzs.10463.

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Shaver, Amanda O., Janneke Wit, Clayton M. Dilks, et al. "Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains." PLOS Pathogens 19, no. 4 (2023): e1011285. http://dx.doi.org/10.1371/journal.ppat.1011285.

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Treatment of parasitic nematode infections in humans and livestock relies on a limited arsenal of anthelmintic drugs that have historically reduced parasite burdens. However, anthelmintic resistance (AR) is increasing, and little is known about the molecular and genetic causes of resistance for most drugs. The free-living roundworm Caenorhabditis elegans has proven to be a tractable model to understand AR, where studies have led to the identification of molecular targets of all major anthelmintic drug classes. Here, we used genetically diverse C. elegans strains to perform dose-response analys
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Panda, Sujogya Kumar, Marijn Daemen, Gunanidhi Sahoo, and Walter Luyten. "Essential Oils as Novel Anthelmintic Drug Candidates." Molecules 27, no. 23 (2022): 8327. http://dx.doi.org/10.3390/molecules27238327.

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Helminths, with an estimated 1.5 billion annual global infections, are one of the major health challenges worldwide. The current strategy of the World Health Organization to prevent helminth infection includes increasing hygienic awareness, providing better sanitation and preventative anthelmintic drug therapy in vulnerable populations. Nowadays, anthelmintic drugs are used heavily in livestock, both in case of infection and as a preventative measure. However, this has led to the development of resistance against several of the most common drugs, such as levamisole, ivermectin and thiabendazol
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Mallmann Júnior, Pedro Marino, Raquel Fraga e. Silva Raimondo, Beatriz Riet Correa Rivero, et al. "Resistance to monepantel in multiresistant gastrointestinal nematodes in sheep flocks in Rio Grande do Sul." Semina: Ciências Agrárias 39, no. 5 (2018): 2059. http://dx.doi.org/10.5433/1679-0359.2018v39n5p2059.

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The excessive, indiscriminate, and continued use of anthelmintic drugs as control methods favors parasite resistance, and this phenomenon has been reported in Brazil and worldwide. The current status of parasite resistance to anthelmintic drugs in sheep flocks in Rio Grande do Sul was assessed by calculating the EPG count in the stool to estimate the prevalence of resistance to the anthelmintic drugs closantel, levamisole, fenbendazole, monepantel, and moxidectin in seven properties. The animals from each flock were randomly distributed in six groups according to the anthelminthic drug used, a
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Laing, Steven T., Al Ivens, Roz Laing, et al. "Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites." Biochemical Journal 432, no. 3 (2010): 505–16. http://dx.doi.org/10.1042/bj20101346.

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Knowledge of how anthelmintics are metabolized and excreted in nematodes is an integral part of understanding the factors that determine their potency, spectrum of activity and for investigating mechanisms of resistance. Although there is remarkably little information on these processes in nematodes, it is often suggested that they are of minimal importance for the major anthelmintic drugs. Consequently, we have investigated how the model nematode Caenorhabditis elegans responds to and metabolizes albendazole, one of the most important anthelmintic drugs for human and animal use. Using a mutan
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Neeru, Malik, and Bhatti Saloni. "In silico prediction of Pharmacokinetic, Bioactivity and Toxicity Parameters of Some Selected benzimidazoles as Anthelminthic Agents." Chemistry Research Journal 7, no. 5 (2022): 68–72. https://doi.org/10.5281/zenodo.11416998.

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<strong>Abstract </strong>Anthelmintics are drugs that are used to treat infections with parasitic worms.<strong> </strong>This includes both flat worms, e.g., flukes and tapeworms and round worms, i.e., nematodes. Anthelmintic resistance in parasites is now widespread. It is a major threat to the sustainability of modern ruminant livestock production, resulting in reduced productivity, compromised animal health and welfare, and increased greenhouse gas emissions through increased parasitism and farm inputs. Treatment with an antihelminthic drug kills worms whose phenotype renders them suscept
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Muthee, JK. "Anthelmintic efficacy of selected medicinal plants against gastrointestinal nematodes in naturally infected sheep in Kenya." Journal of Phytopharmacology 7, no. 2 (2018): 111–15. http://dx.doi.org/10.31254/phyto.2018.7202.

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The use of plants, or their extracts, for the treatment of human and animal ailments, including helminthosis is steeped in antiquity. Anthelmintic resistance in pathogenic helminths has been spreading in prevalence and severity to a point where there is multi-drug resistance against the three major classes of anthelmintics. This globe-wide phenomenon calls for urgent search for different approaches to the control of helminthosis including novel anthelmintic products. The objective of this study was to evaluate the efficacy of plants, which are commonly used in the treatment and control of helm
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Jiminez, Pablo David. "Anthelmintic resistance in the canine hookworm, Ancylostoma caninum." Companion Animal 29, no. 9 (2024): 94–101. http://dx.doi.org/10.12968/coan.2023.0042.

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Hookworms are one of the most common soil-transmitted helminths and can infect a wide variety of mammals. There are three major anthelmintic drug classes currently available for treatment of hookworms in canines: the benzimidazoles, the tetrahydropyrimidines and the macrocylic lactones. In registration studies for the food and drug administration in the USA, febantel, moxidectin and milbemycin oxime all demonstrated efficacy of &gt;99%. Fenbendazole demonstrated efficacy of &gt;98% and pyrantel demonstrated a somewhat variable efficacy, with a mean across studies of approximately 94%, where mo
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Castro, Pablo David Jimenez. "Anthelmintic resistance in the canine hookworm, Ancylostoma caninum." Veterinary Nurse 16, Sup1 (2025): S12—S16. https://doi.org/10.12968/vetn.2025.0009b.

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Hookworms are one of the most common soil-transmitted helminths and can infect a wide variety of mammals. There are three major anthelmintic drug classes currently available for treatment of hookworms in canines: the benzimidazoles, the tetrahydropyrimidines and the macrocylic lactones. In registration studies for the food and drug administration in the USA, febantel, moxidectin and milbemycin oxime all demonstrated efficacy of &gt;99%. Fenbendazole demonstrated efficacy of &gt;98% and pyrantel demonstrated a somewhat variable efficacy, with a mean across studies of approximately 94%, where mo
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Mullagaliyeva, О. A., and Ye N. Zakrepina. "IMPROVING SOME PARAMETERS OF ANTIBODY RESPONSE IN HORSES BY PROBIOTIC AGENTS AGAINST BACKGROUND USE OF MACROCYCLIC LACTONE ANTHELMINTIC." Veterinary Science Today, no. 2 (June 28, 2019): 56–59. http://dx.doi.org/10.29326/2304-196x-2019-2-29-56-59.

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Multiple researches demonstrate that both invasive diseases and use of anthelmintcs adversely affect horse immunity harming the gut flora. Macrocyclic lactone anthelmintics are proved to be highly effective agents but there is insufficient knowledge of their effect on the horse antibody immunity. The issue of immune system correction by the probiotic agents is also underreported. The paper demonstrates the results of the effect made by parascaridosis and strongylidosis invasion and deworming using the macrocyclic lactone drug on some parameters of antibody response in horses. Data on effect of
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Dissertations / Theses on the topic "Anthelmintic drug"

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Stenhouse, Lindsay Joanne. "Characterisation of anthelmintic resistance in a multiple drug resistant Teladorsagia circumcinta isolate." Thesis, University of Glasgow, 2007. http://theses.gla.ac.uk/4251/.

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The purpose of this study was to undertake detailed molecular and phenotypic characterisation of a MDR isolate of T. circumcincta (MTci5) with particular focus upon the mechanisms underlying benzimidazole (BZ) resistance.  MTci5 was isolated from a farm in Central Scotland, which employed a suppressive anthelmintic dosing regime and was closed in 2002 when control of the parasite population became unsustainable.  Underpinning all of the experiments in this study was an anthelmintic selection process whereby the MTci5 isolate was pressured individually with three broad-spectrum anthelmintics (b
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Kenealy, Jessica Scare. "ANTHELMINTIC RESISTANCE IN EQUINE PARASITES: MECHANISMS AND TREATMENT APPROACHES." UKnowledge, 2019. https://uknowledge.uky.edu/gluck_etds/40.

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Anthelmintic resistance of parasites infecting livestock animals is a global problem resulting in decreased animal welfare and production losses. Horses are not exempt from this issue as wide-spread anthelmintic resistance exists among the equine cyathostomins and Parascaris spp. Of the three drug classes available for treating equine intestinal helminths anthelmintic resistance, defined as less than 90-95% drug efficacy, exist to all three. New pharmaceutical control regimens and the elucidation of parasite drug response mechanisms are needed. Two studies were carried out evaluating combinati
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Blackhall, William James. "Genetic variation and multiple mechanisms of anthelmintic resistance in Haemonchus contortus." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37596.

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Anthelmintic treatment of livestock is an important aspect of the control of gastrointestinal parasites. Resistance to anthelmintics is common, and an understanding of resistance requires knowledge of an anthelmintic's mode(s) of action and mechanism(s) of resistance. The parasitic nematode, Haemonchus contortus, has developed resistance to benzimidazoles and avermectins/milbemycins. Proposed mechanisms of resistance are here supported by genetic changes observed in genes whose protein products are believed to interact with these anthelmintics. Statistically significant differences in allele f
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Njue, Annette Igandu. "Mechanisms of anthelmintic resistance in Cooperia oncophora, a nematode parasite of cattle." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84302.

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Anthelmintic resistance is a major problem in livestock, and while it has been slower to emerge in cattle, there are reports of its occurrence. Three broad-spectrum anthelmintics are available for use, and one mechanism of resistance that is common to all is target site alteration. Glutamate-gated chloride channels (GluCls) are an important target for macrocyclic lactone anthelmintics (MLs), while beta-tubulin represents the benzimidazole (BZ) target. The objectives of this thesis were to determine whether GluCls are involved in ML resistance in the cattle parasite Cooperia oncophora ,
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Masuka, Raban Wilfred. "Chemogenomic approaches to drug design : docking-based virtual screening of nematode GPCRs for potential anthelmintic agents." Doctoral thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20968.

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Among common problems affecting human health and veterinary medicines, helmintic infections are major. The pathogens affect 550-750 Million people worldwide, and affect childhood growth, pregnancies, and development of the intellect. Helminths affects the well-being of animals as well including livestock and reduce the animal populations. However, the current anthelmintics are no longer as effective and some strains have developed resistance thus increasing the need for new anthelmintics. Unfortunately, not too much information is available detailing the physiology of helminths. The published
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Kigen, Gabriel Kimutai. "Assessment of Drug Interactions Between Antiretroviral and the Anthelminthic drugs." Thesis, University of Liverpool, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507508.

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Souhaili-El, Amri Hajar. "Albendazole : métabolisme et régulation des enzymes hépatiques du métabolisme des xénobiotiques." Nancy 1, 1988. http://www.theses.fr/1988NAN10122.

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Woolley, Ley Hwee. "Synthesis of potential anthelminthic drugs." Thesis, University of Salford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258257.

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Benchaoui, Hafid Abdelaali. "Factors affecting the pharmacokinetics, metabolism and efficacy of anthelmintic drugs." Thesis, University of Glasgow, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284569.

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Gokbulut, Cengiz. "Plasma disposition, faecal excretion, metabolism and chirality of anthelmintic drugs in horses." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323707.

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Books on the topic "Anthelmintic drug"

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van, Wyk J. A., Schalkwyk P. C. van, and World Association for the Advancement of Veterinary Parasitlogy., eds. Managing anthelmintic resistance in endoparasites: Workshop held at the 16th International Conference of the World Association for the Advancement of Veterinary Parasitolgy, 10-15 August, 1997, Sun City, South Africa. The Organisers, 1997.

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Woolley, Ley Hwee. Synthesis of potential anthelmintic drugs. University of Salford, 1989.

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Hoberg, Eric P. A compendium of chemotherapy: Anthelmintic and antiprotozoal compounds. Oregon State University, 1989.

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Organization, World Health, ed. WHO model prescribing information: Drugs used in parasitic diseases. WHO, 1990.

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Crompton, D. W. T. 1937- and World Health Organization, eds. Preventive chemotherapy in human helminthiasis: Coordinated use of anthelminthic drugs in control interventions : a manual for health professionals and programme managers. World Health Organization, 2006.

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Chandrakant, Mahajan Kiran. Formulation and Optimization of Self Emulsifying Drug Delivery System for Effective Anthelmintic Therapy. Quadry, Fatima, 2023.

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Resistance in Nematodes to Anthelmintic Drugs. CSIRO Division of Animal Health, 1985.

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IAEA. Development of Radiometric and Allied Analytical Methods and Strategies to Strengthen National Residue Control Programmes for Antibiotic and Anthelmintic Veterinary Drug Residues: Final Report of a Coordinated Research Project. International Atomic Energy Agency, 2016.

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Selzer, Paul M., and Conor R. Caffrey. Parasitic Helminths: Targets, Screens, Drugs and Vaccines. Wiley & Sons, Limited, John, 2012.

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Selzer, Paul M., and Conor R. Caffrey. Parasitic Helminths: Targets, Screens, Drugs and Vaccines. Wiley & Sons, Incorporated, John, 2017.

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Book chapters on the topic "Anthelmintic drug"

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Riaz, Aayesha, Faiza Bano, Manuela Marescotti, Evelyn Saba, and Zahid Manzoor. "Anthelmintic Resistance." In Antiparasitic Drug Resistance in Veterinary Practice. CABI, 2024. http://dx.doi.org/10.1079/9781800622807.0003.

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Kiang, Tony K. L., Kyle John Wilby, and Mary H. H. Ensom. "Antiprotozoal and Anthelmintic Agents." In Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-72416-4_13.

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Thangaraj, Parimelazhagan. "In Vitro Anthelmintic Assay." In Progress in Drug Research. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-26811-8_12.

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Edwards, Geoffrey. "Antiprotozoal and Anthelmintic Agents." In Drug Interactions in Infectious Diseases. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-213-7_17.

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Geary, Timothy G., Judy Sakanari, and Conor R. Caffrey. "Anthelmintic drug discovery: Into the future." In A Century of Parasitology. John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118884799.ch15.

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Tuck, Sarah, Ambrose Furey, and Martin Danaher. "Analysis of Anthelmintic and Anticoccidial Drug Residues in Animal&;#x02010;Derived Foods." In Chemical Analysis of Non&;#x02010;antimicrobial Veterinary Drug Residues in Food. John Wiley &;#38; Sons, Inc., 2016. http://dx.doi.org/10.1002/9781118696781.ch5.

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Mehlhorn, Heinz. "Anthelmintic Drugs Advancements." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_4519.

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Mehlhorn, Heinz. "Anthelmintic Drugs Advancements." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_4519-1.

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Ferreira, Henrique Bunselmeyer, Marcelo Pasa Panesso, and Marina Monteiro Guedes. "Repurposing Drugs as Anthelmintics: Expanding the Therapeutic Arsenal Against Parasitic Worm Infections." In Drug Repurposing. CRC Press, 2025. https://doi.org/10.1201/9781032725826-7.

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Geary, Timothy G., and Eliane Ubalijoro. "Searching for Drugs That Target Multiple Receptors for Anthelmintics from African Natural Products." In Drug Discovery in Africa. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-28175-4_6.

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Conference papers on the topic "Anthelmintic drug"

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Murugathas, Thanujah, Nivethika Baskaran, P. A. Dinesh Coonghe, Manoji Gitanjali Sathiadas, and Sinnadurai Thuvaragan. "Association of factors on parental knowledge and practice regarding Anthelmintic drugs in a Tertiary Hospital, Sri Lanka." In 2nd International Conference on Public Health and Well-being. iConferences (Pvt) Ltd, 2021. http://dx.doi.org/10.32789/publichealth.2021.1006.

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Worm infestations are one of the significant health problems affecting children in developing countries. It is highly prevalent among poverty-stricken communities due to poor hygiene. The objective of this study was to assess the knowledge and practice on anthelmintic drugs and the influence of selected factors and knowledge on worm infestation among parents of pediatric patients attending OPD at a Teaching Hospital, Sri Lanka. It was a descriptive cross-sectional study. A validated interviewer-administered questionnaire was used as a study instrument. A systematic random sampling method was u
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Kapo, Naida, Jasmin Omeragić, Šejla Goletić, Adis Softić, Emina Šabić, and Teufik Goletić. "Phenotypic and Genotypic Analysis of Anthelmintic Resistance." In Socratic Lectures 8. University of Lubljana Press, 2023. http://dx.doi.org/10.55295/psl.2023.i3.

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A growing issue on a global scale is the emergence of helminth species and populations that are resistant to one or more anthelmintics. The majority of currently available anthelmintics used to control parasitic nematodes of cattle and sheep belong to only three main groups, benzimidazoles, imidazothiazoles and avermectins/milbemycins. The availability of reliable and precise techniques for its identification and monitoring is a critical component of the success of helminth control programs intended to prevent the spread of resistance in nematode populations. In vivo method like fecal egg coun
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Kapo, Naida, Jasmin Omeragić, Faruk Tandir, Indira Mujezinović, Ahmed Smajlović, and Ermin Šaljić. "Anthelmintic Resistance in Gastrointestinal Nematodes of Ru-minants." In Socratic Lectures 7. University of Lubljana Press, 2022. http://dx.doi.org/10.55295/psl.2022.d9.

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Gastrointestinal nematode (GIN) infections remain one of the most prevalent and important issue affecting ruminants worldwide. Until date, the majority of GIN control has relied on the administra-tion of chemical anthelmintic medications on a regular basis, in recent years, the problem of anthel-mintic resistance has reached new heights where it can no longer be ignored as a major issue in the control of parasites of livestock. Anthelmintics are generally used at farmers' discretion, with no restrictions to access to commercially available drugs and without any assistance from veterinarians. T
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Engasev, Serghei, Ekaterina Engaseva, V. Kolesnikov та Mariya Lopteva. "Иверсан - раствор для орального применения при нематодозах овец". У International Symposium "Actual problems of zoology and parasitology: achievements and prospects". Institute of Zoology, 2018. https://doi.org/10.53937/9789975665902.53.

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Klimenkova, I., and N. Spiridonova. "THE INFLUENCE OF COMPLEX THERAPY ON THE BODY OF CATTLE WITH COMBINED INVASIONS." In SCIENTIFIC SUPPORT FOR LIVESTOCK BREEDING IN SIBERIA. Krasnoyarsk Scientific Research Institute of Agriculture is a separate division of the Federal Research Center KSC SB RAS, 2024. https://doi.org/10.52686/conferencearticle_67597cef89bac0.44418221.

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The dynamics of the content of vitamins A, C, E, B1 and B2 in whole blood and its serum was determined in cattle suffering from fascioliasis and strongylatosis of the gastrointestinal tract, as well as as a result of treatment with an anthelmintic drug in combination with vitamins. The obtained indicators will complement the information on vitamin metabolism in this type of animal under normal conditions and with parasitic diseases, which also serve as a basis for adjusting therapeutic and preventive measures for combined infestations.
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Thuvaragan, S., H. M. P. M. Jeyasinghe, and A. Murugananthan. "Comparative Evaluation of in - vitro Anthelmintic Activity of Sap, Fruit bulb, and Root of Borassus flabellifer." In 2nd International Conference on Public Health and Well-being. iConferences (Pvt) Ltd, 2022. http://dx.doi.org/10.32789/publichealth.2021.1011.

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Helminth infections are major health problems, especially in developing countries with warm and humid environments. Limited synthetic drugs are available for treating helminth infections, and some of them showed resistance to helminths. Phytoconstituents can be used to develop cheap and effective anthelminthic drugs. Borassus flabellifer has been used in traditional medicine, in addition to consuming as food. This study was designed to evaluate the comparative in vitro anthelmintic activities of aqueous and methanol extracts of root, fruit pulp, and sap of Borassus flabellifer using two differ
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Panova, D. S., and O. A. Panova. "EXPERIENCE OF SANITATION OF LIVESTOCK FARMS WITH PARASITOSIS." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”, 2023. http://dx.doi.org/10.31016/978-5-6048555-6-0.2023.24.343-348.

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Parasitic diseases cause significant damage to livestock affecting the productivity and&#x0D; clinical condition of sheep and goats. The purpose of our research was to provide a&#x0D; comprehensive diagnosis of endoparasites in ruminants kept on a private livestock&#x0D; farm in the Moscow Region, and to develop and propose a scheme of therapeutic&#x0D; and preventive measures. Fifty five fecal samples were studied: 19 samples from cows&#x0D; (4 from calves, 15 from adults), 24 from goats (10 from goatlings, 14 from adults), 12&#x0D; from sheep (all age groups were kept together). Fecal sample
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Kim, Yoon-Jae, Eunhye Oh, Tae-Min Cho, et al. "Abstract 703: An anthelmintic drug, flubendazole, exerts antitumor effects in triple-negative breast cancer via targeting cancer stem-like properties." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-703.

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Kim, Yoon-Jae, Eunhye Oh, Tae-Min Cho, et al. "Abstract 703: An anthelmintic drug, flubendazole, exerts antitumor effects in triple-negative breast cancer via targeting cancer stem-like properties." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-703.

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Khalikov, S. S. "FEATURES OF MECHANOCHEMICAL TECHNOLOGY IN THE DEVELOPMENT OF PARASITOCIDES." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”, 2023. http://dx.doi.org/10.31016/978-5-6048555-6-0.2023.24.498-502.

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The purpose of the research is to study the features of the mechanochemical&#x0D; modification of medicinal substances with low solubility in water. According to&#x0D; the Biopharmaceutics Classification System, about 6% of medicinal substances&#x0D; belong to the group of insoluble medicinal substances, and about 47%, to practically&#x0D; insoluble medicinal substances, i.e. more than a half substances have problems with&#x0D; solubility, and therefore bioavailability and pharmacological activity. To achieve&#x0D; the therapeutic effect of such substances, it is necessary to deliberately incr
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Reports on the topic "Anthelmintic drug"

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Tharaldson, Katie. An Overview of Anthelmintic Drugs in Ascaris suum Intestine. Iowa State University, 2019. http://dx.doi.org/10.31274/cc-20240624-195.

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