Academic literature on the topic 'Anthelmintics. Parasites'

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Journal articles on the topic "Anthelmintics. Parasites"

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Abongwa, Melanie, Richard J. Martin, and Alan P. Robertson. "A brief review on the mode of action of antinematodal drugs." Acta Veterinaria 67, no. 2 (2017): 137–52. http://dx.doi.org/10.1515/acve-2017-0013.

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Abstract Anthelmintics are some of the most widely used drugs in veterinary medicine. Here we review the mechanism of action of these compounds on nematode parasites. Included are the older classes of compounds; the benzimidazoles, cholinergic agonists and macrocyclic lactones. We also consider newer anthelmintics, including emodepside, derquantel and tribendimidine. In the absence of vaccines for most parasite species, control of nematode parasites will continue to rely on anthelmintic drugs. As a consequence, vigilance in detecting drug resistance in parasite populations is required. Since r
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Martin, R. J., S. Puttachary, S. K. Buxton, S. Verma, and A. P. Robertson. "The Conqueror Worm: recent advances with cholinergic anthelmintics and techniques excite research for better therapeutic drugs." Journal of Helminthology 89, no. 4 (2014): 387–97. http://dx.doi.org/10.1017/s0022149x1400039x.

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AbstractThe following account is based on a review lecture given recently at the British Society of Parasitology. We point out that nematode parasites cause very widespread infections of humans, particularly in economically underdeveloped areas where sanitation and hygiene are not adequate. In the absence of adequate clean water and effective vaccines, control and prophylaxis relies on anthelmintic drugs. Widespread use of anthelmintics to control nematode parasites of animals has given rise to the development of resistance and so there is a concern that similar problems will occur in humans i
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French, Katherine E. "Plant-Based Solutions to Global Livestock Anthelmintic Resistance." Ethnobiology Letters 9, no. 2 (2018): 110–23. http://dx.doi.org/10.14237/ebl.9.2.2018.980.

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Anthelmintic resistance in livestock is increasing globally. Livestock intestinal parasites now develop resistance to synthetic anthelmintics within 2–10 years, collectively costing billions of dollars annually in lost revenue around the world. Over-reliance on commercial drugs and dips and changes in livestock management practices are key drivers of this trend. To date, current research has focused on identifying new anthelmintics from bacterial and fungal sources or even synthesizing new drugs that target parasite metabolism or reproduction. Plant-derived anthelmintics are a promising altern
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PRICHARD, ROGER K. "Markers for benzimidazole resistance in human parasitic nematodes?" Parasitology 134, no. 8 (2007): 1087–92. http://dx.doi.org/10.1017/s003118200700008x.

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SUMMARYBenzimidazole (BZ) resistance is widespread and appears to be readily selected in a variety of nematode parasites of animals. There have been reports of a lack of efficacy of BZ anthelmintics against soil transmitted nematode parasites of humans. However, resistance to BZs in nematodes of humans has not been confirmed. It is difficult to perform tests to confirm anthelmintic resistance in humans for a variety of technical and ethical reasons. The use of anthelmintic drugs for the control of helminth parasites in people is increasing massively as a result of numerous programmes to contro
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MARTIN, R. J., A. P. ROBERTSON, and H. BJORN. "Target sites of anthelmintics." Parasitology 114, no. 7 (1997): 111–24. http://dx.doi.org/10.1017/s0031182097001029.

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This paper reviews sites of action of anthelmintic drugs including: (1) levamisole and pyrantel, which act as agonists at nicotinic acetylcholine receptors of nematodes; (2) the avermectins, which potentiate or gate the opening of glutamate-gated chloride channels found only in invertebrates; (3) piperazine, which acts as an agonist at GABA gated chloride channels on nematode muscle; (4) praziquantel, which increases the permeability of trematode tegument to calcium and results in contraction of the parasite muscle; (5) the benzimidazoles, like thiabendazole, which bind selectively to parasite
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Sangster, N. "Pharmacology of anthelmintic resistance." Parasitology 113, S1 (1996): S201—S216. http://dx.doi.org/10.1017/s0031182000077982.

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SUMMARYAnthelmintic resistance has compromised the control of nematode parasites in several animal-based industries. Studies of resistance have not only improved our understanding of this phenomenon but also shed light on physiological systems of parasitic helminths. In addition, research on molecular aspects of anthelmintic resistance may provide selectable markers for use in future transfection studies with helminths. Several anthelmintics act on helminth neuromuscular systems. Drugs such as levamisole are cholinergic agonists and, based on pharmacological studies, levamisole-resistant nemat
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Mirza, Zeynep, Ernesto R. Soto, Yan Hu, et al. "Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes." Molecules 25, no. 13 (2020): 2958. http://dx.doi.org/10.3390/molecules25132958.

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Soil-transmitted nematodes (STN) infect 1–2 billion of the poorest people worldwide. Only benzimidazoles are currently used in mass drug administration, with many instances of reduced activity. Terpenes are a class of compounds with anthelmintic activity. Thymol, a natural monoterpene phenol, was used to help eradicate hookworms in the U.S. South circa 1910. However, the use of terpenes as anthelmintics was discontinued because of adverse side effects associated with high doses and premature stomach absorption. Furthermore, the dose–response activity of specific terpenes against STNs has been
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Mayaki, Abubakar Musa, Fatimah Folashade Mohammed, and Sherifat Banke Idris. "Anthelmintic Resistance and Associated Management Practices in Local Horses in Sokoto Metropolis, Nigeria." Macedonian Veterinary Review 41, no. 1 (2018): 55–64. http://dx.doi.org/10.1515/macvetrev-2017-0031.

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Abstract This study was carried out to assess the management practices used in the control of gastrointestinal (GI) nematodes of horses and to determine the efficacy of three anthelmintics commonly used in Sokoto metropolis. A questionnaire was administered on management practices, while an anthelmintic efficacy test was carried out using 15 horses. The 15 horses were divided into three groups (A, B and C) comprising of 5 each and treated with albendazole, ivermectin and fenbendazole, respectively. The faecal egg count reduction test (FECRT) was used to determine the efficacy and faecal cultur
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Wright, Ian. "CPD article: Equine gastrointestinal parasite infections." UK-Vet Equine 4, no. 5 (2020): 156–60. http://dx.doi.org/10.12968/ukve.2020.4.5.156.

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Horses can be infected by a wide range of gastrointestinal parasites including roundworms, tapeworms and bot flies. Anthelmintics have formed the basis of intestinal worm control in horses through routine use for many years but the development of anthelmintic resistance now means that strategies are required to limit anthelmintic use while minimising parasitic disease. Pasture and stable hygiene, accurate dosing of horses and faecal testing are all key to reducing anthelmintic use, while not compromising welfare. A fundamental understanding of the parasites involved and communication with clie
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Jamieson, S., and F. D. DeB Hovell. "Quebracho (Schinopsis quebracho-colorado) tannin for the treatment of sheep gastrointestinal parasites. Effect on faecal egg counts and lamb growth." Proceedings of the British Society of Animal Science 2009 (April 2009): 34. http://dx.doi.org/10.1017/s1752756200028738.

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Farmers have become heavily reliant on anthelmintics for the control of nematode parasites Due to the widespread development of anthelmintic resistance, alternative approaches for control of nematode parasites are needed. Cruden and Hovell (2008) reported that commercial lambs treated with quebracho tannin had reduced faecal egg counts and improved lamb growth. This paper reports a second in vivo study with quebracho tannins at higher dose rates in lambs.
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Dissertations / Theses on the topic "Anthelmintics. Parasites"

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Stewart, M. T. "Neuromusculature development and neurobiology of platyhelminth parasites of fish." Thesis, Queen's University Belfast, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273299.

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Scott, Elspeth Warren. "Effects of benzimidazole anthelmintics on nematode parasites of sheep." Thesis, University of Glasgow, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284783.

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Lanusse, Carlos Edmundo. "Pharmacokinetics of propylthio-benzimidazole anthelmintics : modulation of liver biotransformation in sheep and cattle." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=70364.

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The aim of this research was to determine the influence of route of administration, drug formulation and modified-liver metabolism on the pharmacokinetic and metabolic patterns of benzimidazole anthelmintics in ruminants. Both route of administration and formulation dramatically affected the bioconversion of netobimin (NTB) pro-drug, N-methoxycarbonyl-N$ sp prime$-(2-nitro-5-propylphenylthio)-${ rm N} sp{ prime prime}$-(2-ethyl sulphonic acid) guanidine, and the bioavailability and disposition kinetics of its active albendazole (ABZ) metabolites in both sheep and cattle. The efficacy of NTB co
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LeShure, Shirron Nicole. "Use of Naturally Occurring Anthelmintics to Control Gastrointestinal Parasites in Small Ruminants." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397649276.

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Njue, Annette Igandu. "Mechanisms of anthelmintic resistance in Cooperia oncophora, a nematode parasite of cattle." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84302.

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Anthelmintic resistance is a major problem in livestock, and while it has been slower to emerge in cattle, there are reports of its occurrence. Three broad-spectrum anthelmintics are available for use, and one mechanism of resistance that is common to all is target site alteration. Glutamate-gated chloride channels (GluCls) are an important target for macrocyclic lactone anthelmintics (MLs), while beta-tubulin represents the benzimidazole (BZ) target. The objectives of this thesis were to determine whether GluCls are involved in ML resistance in the cattle parasite Cooperia oncophora ,
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Osterman, Lind Eva. "Prevalence and control of strongyle nematode infections of horses in Sweden /." Uppsala : Dept. of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2005. http://epsilon.slu.se/200529.pdf.

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Hrabok, Jackie T. "Nematode parasites of reindeer in Fennoscandia : population dynamics, anthelmintic control and its environmental impact /." Uppsala : Dept. of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/200689.pdf.

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Panchadcharam, Chandrawathani. "Problems in the control of nematode parasites of small ruminants in Malaysia : resistance to anthelmintics and the biological control alternative /." Uppsala : Dept of Biomedical Sciences and Veterinary Public Health, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/v172.pdf.

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Menkir, Mekonnen Sissay. "Helminth parasites of sheep and goats in Eastern Ethiopia : epidemiology, and anthelmintic resistance and its management /." Uppsala : Dept. of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2007. http://epsilon.slu.se/200752.pdf.

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Lopes, Ana Sofia de Pinho. "Implementação do projeto rastreio STOP (Simples Teste de Ovos Parasitários) em equídeos em Portugal Continental." Master's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2013. http://hdl.handle.net/10400.5/5491.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Os parasitas são reconhecidos como importante causa de doença em equídeos. Ainda hoje, existem graves lacunas no que diz respeito ao controlo das principais parasitoses, quer pelo desconhecimento por parte dos proprietários do fenómeno parasitário e da necessidade do seu controlo, quer pela necessidade de um papel mais ativo dos médicos veterinários no tratamento e controlo das parasitoses. Com base nesta situação, a Merial Saúde Animal, Grupo Sanofi em colaboração com o Centro de Investigação Interdisciplinar em Sanidade Animal, Fac
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Books on the topic "Anthelmintics. Parasites"

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Oakley, G. A. Anthelmintics for cats and dogs. Anpar, 1991.

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Oakley, G. A. Ivermectin: The Veterinary Handbook. Anpar Books, 1990.

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Parasitic Helminths Targets Screens Drugs And Vaccines. Wiley-VCH Verlag GmbH, 2012.

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Selzer, Paul M., and Conor R. Caffrey. Parasitic Helminths: Targets, Screens, Drugs and Vaccines. Wiley & Sons, Incorporated, John, 2012.

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Selzer, Paul M., and Conor R. Caffrey. Parasitic Helminths: Targets, Screens, Drugs and Vaccines. Wiley & Sons, Limited, John, 2012.

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Selzer, Paul M., and Conor R. Caffrey. Parasitic Helminths: Targets, Screens, Drugs and Vaccines. Wiley & Sons, Incorporated, John, 2012.

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Selzer, Paul M., and Conor R. Caffrey. Parasitic Helminths: Targets, Screens, Drugs and Vaccines. Wiley & Sons, Incorporated, John, 2017.

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Nolan, T. J., T. B. Nutman, and G. A. Schad. Strongyloidosis. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0064.

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Strongyloidosis is an intestinal parasitism caused by the threadworm, Strongyloides stercoralis. The parasite, occurring in dogs, primates and man, is found throughout the moist tropics, as well as in temperate areas where poor sanitation or other factors facilitate the occurrence of faecally transmitted organisms. In some parts of the world, notably Africa and New Guinea, human infections caused by S. fülleborni have been reported. In Africa, the latter is primarily a parasite of primates, but in New Guinea, no animal host is known. S. stercoralis is unique among zoonotic nematodes, in that l
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World Health Organization (WHO). Preventive chemotherapy in human helminthiasis. World Health Organization, 2006.

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Bossche, Hugo Vanden. Chemotherapy of Gastrointestinal Helminths. Brand: Springer, 2011.

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Book chapters on the topic "Anthelmintics. Parasites"

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Hu, Yan, and Raffi V. Aroian. "Promise of Bacillus thuringiensis Crystal Proteins as Anthelmintics." In Parasitic Helminths. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652969.ch16.

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Geary, Timothy G. "Mechanism-Based Screening Strategies for Anthelmintic Discovery." In Parasitic Helminths. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652969.ch8.

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Fankhauser, Rebecca, Linsey R. Cozzie, Bakela Nare, Kerrie Powell, Ann E. Sluder, and Lance G. Hammerland. "Use of Rodent Models in the Discovery of Novel Anthelmintics." In Parasitic Helminths. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652969.ch11.

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de Hostos, Eugenio L., and Tue Nguyen. "Anthelmintic Drugs: Tools and Shortcuts for the Long Road from Discovery to Product." In Parasitic Helminths. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652969.ch13.

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Lees, Kristin, Ann Sluder, Niroda Shannan, Lance Hammerland, and David Sattelle. "Ligand-Gated Ion Channels as Targets for Anthelmintic Drugs: Past, Current, and Future Perspectives." In Parasitic Helminths. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652969.ch1.

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Burns, Andrew R., and Peter J. Roy. "To Kill a Mocking Worm: Strategies to Improve Caenorhabditis elegans as a Model System for use in Anthelmintic Discovery." In Parasitic Helminths. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652969.ch12.

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Hrckova, Gabriela, and Samuel Velebny. "Natural Compounds Exerting Anthelmintic and/or Host-Protecting Effects During Parasitic Infections." In Pharmacological Potential of Selected Natural Compounds in the Control of Parasitic Diseases. Springer Vienna, 2012. http://dx.doi.org/10.1007/978-3-7091-1325-7_3.

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Churcher, Thomas S., Ray M. Kaplan, Bernadette F. Ardelli, Jan M. Schwenkenbecher, María-Gloria Basáñez, and Patrick J. Lammie. "Mass Treatment of Parasitic Disease: Implications for the Development and Spread of Anthelmintic Resistance." In Antimicrobial Resistance. KARGER, 2010. http://dx.doi.org/10.1159/000298760.

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Barrón-Bravo, Oscar, Ismael Montiel-Maya, Ana Cruz-Avalos, Fidel Avila-Ramos, Jaime Molina Ochoa, and César Angel-Sahagún. "Entomopathogenic Nematodes: Biological Model of Studies with Anthelmintics." In Nematodes - Recent Advances, Management and New Perspectives [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99663.

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Anthelmintics used in animals to combat parasitic infections are mainly excreted in manure and cause negative effects on the environment and decomposers. Nematodes are associated with the rhizosphere; some are gastrointestinal parasites of animals, and others regulate insects and other arthropods (entomopathogenic nematodes) and are considered beneficial. The habitat and the similarities that exist among them give the opportunity to use nematodes as a biological model. The availability of target organisms is not always feasible; therefore, experimental studies with models similar to those of the target organisms are a possibility. In veterinary clinics, the study of drug susceptibility is a fundamental tool to monitor the development of resistance. To conserve the biodiversity of the environment, it is necessary to make adequate use of anthelmintics, avoid resistance to these pesticides and prevent the used products from damaging populations of beneficial organisms.
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"Anthelmintic Resistance." In Handbook of Equine Parasite Control. John Wiley & Sons, Inc., 2018. http://dx.doi.org/10.1002/9781119382829.ch8.

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Conference papers on the topic "Anthelmintics. Parasites"

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Makhubu, FN, MC Khosa, and LJ McGaw. "Can plants with good anthelmintic activity against free-living and animal parasitic nematodes be effective against plant parasitic nematodes?" In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399736.

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