Academic literature on the topic 'Anthranilic acid derivative'

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Journal articles on the topic "Anthranilic acid derivative"

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Chandrashekhara, Kumar B* Arun A. Bhagwath Chandrashekar K. S. "Pharmaceutical Chemistry Of Anthranilic Acid Derivatives: A Brief Review." International Journal of Pharmaceutical Sciences 2, no. 7 (2024): 2143–74. https://doi.org/10.5281/zenodo.13131906.

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Anthranilic acid is a benzenoid compound that has adjacent active important two reactive groups namely carboxylic acid group (-COOH) and amino group (-NH<sub>2</sub>). Consequently fascinating anthranilic acid derivatives have been prepared through both the active functional groups.&nbsp; The literature review reveals an experiential and holistic approach of various manufacturing procedures and skills used for the production of anthranilic acid analogues and anthranilic scaffold along with the biological activities of some of the promising derived anthranilic acid molecules.&nbsp; Pharmacology
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Platten, Michael, Peggy P. Ho, Sawsan Youssef, et al. "Treatment of Autoimmune Neuroinflammation with a Synthetic Tryptophan Metabolite." Science 310, no. 5749 (2005): 850–55. http://dx.doi.org/10.1126/science.1117634.

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Local catabolism of the amino acid tryptophan (Trp) by indoleamine 2,3-dioxygenase (IDO) is considered an important mechanism of regulating T cell immunity. We show that IDO transcription was increased when myelin-specific T cells were stimulated with tolerogenic altered self-peptides. Catabolites of Trp suppressed proliferation of myelin-specific T cells and inhibited production of proinflammatory T helper–1 (TH1) cytokines. N-(3,4,-Dimethoxycinnamoyl) anthranilic acid (3,4-DAA), an orally active synthetic derivative of the Trp metabolite anthranilic acid, reversed paralysis in mice with expe
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Hartleb, Ina, and K. Seifert. "A Novel Anthranilic Acid Derivative fromIsatis tinctoria." Planta Medica 60, no. 06 (1994): 578–79. http://dx.doi.org/10.1055/s-2006-959577.

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Kamal, Ahmed, and Shaimaa Adnan. "Synthesis, Characterization and Study the Biological Activity for Some New Heterocyclic Derivative from 4,5-dichloro Imidazole." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 04 (2022): 1542–46. http://dx.doi.org/10.25258/ijddt.12.4.10.

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Creating a multi-step method for synthesizing heterocyclic compounds is the goal of this research. The first step involves reacting 4,5-dichloro-2- phenylenediamine with 3- amino- 4-“hydroxybenzoic acid to produce an imidazole derivative (1), which then reacts with salicyldehyde to produce the azo compound (2). Two, a Schiff base derivative is produced via a reaction with p-chloro aniline (23). Final steps involve reactions (3) with chloroacetyl chloride, alanine, sodium azide, thioglycol acid, anthranilic acid, and maleic anhydride, yielding beta-lactam derivatives (4), imidazolidine (5), tet
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Cole, Jennifer E., Nagore Astola, Adam P. Cribbs, et al. "Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development." Proceedings of the National Academy of Sciences 112, no. 42 (2015): 13033–38. http://dx.doi.org/10.1073/pnas.1517820112.

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Atherosclerosis is the major cause of cardiovascular disease (CVD), the leading cause of death worldwide. Despite much focus on lipid abnormalities in atherosclerosis, it is clear that the immune system also has important pro- and antiatherogenic functions. The enzyme indoleamine-2,3-dioxygenase (IDO) catalyses degradation of the essential amino acid tryptophan into immunomodulatory metabolites. How IDO deficiency affects immune responses during atherogenesis is unknown and we explored potential mechanisms in models of murine and human atherosclerosis. IDO deficiency in hypercholesterolemic Ap
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Amr, Abd El-Galil E., Alhussein A. Ibrahimd, Mohamed F. El-Shehry, Hanaa M. Hosni, Ahmed A. Fayed, and Elsayed A. Elsayed. "In Vitro and In Vivo Anti-Breast Cancer Activities of Some Newly Synthesized 5-(thiophen-2-yl)thieno-[2,3-d]pyrimidin-4-one Candidates." Molecules 24, no. 12 (2019): 2255. http://dx.doi.org/10.3390/molecules24122255.

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In this study, some of new thiophenyl thienopyrimidinone derivatives 2–15 were prepared and tested as anti-cancer agents by using thiophenyl thieno[2,3-d]pyrimidinone derivative 2 as a starting material, which was prepared from cyclization of ethyl ester derivative 1 with formamide. Treatment of 2 with ethyl- chloroacetate gave thienopyrimidinone N-ethylacetate 3, which was reacted with hydrazine hydrate or anthranilic acid to afford acetohydrazide 4 and benzo[d][1,3]oxazin-4-one 5, respectively. Condensation of 4 with aromatic aldehydes or phenylisothiocyanate yielded Schiff base derivatives
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Soliman, Mohamed H., Sahar S. El-Sakka, and Eman M. El-Shalakany. "Synthesis and Reactions of Some Novel 4H-3,1-Benzoxazinone Bearing Chalcone Moiety with Antibacterial Evaluation." Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry 79, no. 597 (2023): 441–46. http://dx.doi.org/10.55815/406209.

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2-[3-(4-Methoxy-3-methylphenyl)-3-oxoprop-1-enyl]-4H-3,1-benzoxazin-4-one 2 was synthesized by the cyclization of the respective N-acylanthranilc acid 1. The bromination of benzoxazinone 2 afforded the dibromo anthranilic acid 3, which gave N-pyrazolyl anthranilic acid 4 on treatment with hydrazine. The ethanolysis of benzoxazinone 2 with sodium ethoxide gave ethyl anthranilate derivative 5 which on treatment with amines furnished the corresponding ethyl N-substitutedanthranilate 6a-b. The aminolysis of benzoxazinone 2 with ammonium acetate, primary amines and/ or secondary amines afforded the
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Carbone, Marianna, Laura Núñez-Pons, M. Letizia Ciavatta, Francesco Castelluccio, Conxita Avila, and Margherita Gavagnin. "Occurrence of a Taurine Derivative in an Antarctic Glass Sponge." Natural Product Communications 9, no. 4 (2014): 1934578X1400900. http://dx.doi.org/10.1177/1934578x1400900408.

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The n-butanol extract of an Antarctic hexactinellid sponge, Anoxycalyx (Scolymastra) joubini, was found to contain a taurine-conjugated anthranilic acid, never reported so far either as a natural product or by synthesis. The compound was inactive against human cancer cells in an in vitro growth inhibitory test, and also showed no antibacterial activity.
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McCloskey, Patrick J., and Arthur G. Schultz. "Enantioselective total synthesis of (+)-perhydro-219A from an anthranilic acid derivative." Journal of Organic Chemistry 53, no. 7 (1988): 1380–83. http://dx.doi.org/10.1021/jo00242a007.

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Derr, James Bennett, Katarzyna Rybicka-Jasińska, Eli Misael Espinoza, et al. "On the Search of a Silver Bullet for the Preparation of Bioinspired Molecular Electrets with Propensity to Transfer Holes at High Potentials." Biomolecules 11, no. 3 (2021): 429. http://dx.doi.org/10.3390/biom11030429.

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Biological structure-function relationships offer incomparable paradigms for charge-transfer (CT) science and its implementation in solar-energy engineering, organic electronics, and photonics. Electrets are systems with co-directionally oriented electric dopes with immense importance for CT science, and bioinspired molecular electrets are polyamides of anthranilic-acid derivatives with designs originating from natural biomolecular motifs. This publication focuses on the synthesis of molecular electrets with ether substituents. As important as ether electret residues are for transferring holes
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Dissertations / Theses on the topic "Anthranilic acid derivative"

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Wiklund, Per. "Synthesis of heterocycles from anthranilic acid and its derivatives /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-913-7/.

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Liu, Yi Ting, and 劉怡婷. "The Pharmacokinetics of Anti-inflammatory Anthranilic Acid Derivatives in Rats." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/39680594300339525197.

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碩士<br>長庚大學<br>中醫學系天然藥物<br>99<br>The anthranilic acid derivatives, DSM-RX 116 (Ethyl 2- (2- fluorobenzamido) benzoate), DSM-RX 78 (Methyl 2-(2-fluorobenzamido)benzoate), and their hydrolysis compound, SMP-3 (2-(2-fluorobenzamido)benzoic acid), were synthesized. In previous study, DSM-RX 78 and DSM-RX 116 showed inhibitory effects on fMLP-induced superoxide anion generation in neutrophil with IC50 value of 0.65 and 0.17 μM. Furthermore, i.v. administration of DSM-RX 78 and DSM-RX 116 in rats subjected to trauma - hemorrhagic (T/H) shock caused a significant improvement in multiple organ dysfunct
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Southern, Cathrine Ann. "Spectroscopy of anthranilic acid and its derivatives in a supersonic jet /." 2002. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3060268.

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Book chapters on the topic "Anthranilic acid derivative"

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Kikelj, D. "From Anthranilic Acid Derivatives and Nitriles." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00761.

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Kikelj, D. "From Anthranilic Acid Derivatives and Guanidine, Imidates, or Formimidamides." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00760.

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Kikelj, D. "From Anthranilic Acid Derivatives and Cyanates, Thiocyanates, Urea, or Carbamates." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00759.

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Kikelj, D. "From Anthranilic Acid Derivatives and Amides or Thioamides (Niementowski's Synthesis)." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00762.

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Kikelj, D. "From Anthranilic Acid Derivatives and Other N—C Synthons (1,3,5-Triazine, Gold's Reagent, Activated Nitriles)." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00763.

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Conference papers on the topic "Anthranilic acid derivative"

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Kwon, IS, K. Kwak Jong Hwan, S. Pyo, AR Kim, and FJ Schmitz. "A New Anthranilic Acid Derivative from Oscarella stillans as Regulator of Inflammatory Cytokines in Macrophages." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608162.

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