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1

Malinovsky, A. V. "Is anthranil acid subject to deamination in animals?" Timiryazev Biological Journal, no. 3 (December 19, 2024): 61–68. https://doi.org/10.26897/2949-4710-2024-2-3-61-68.

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All metabolic pathways of natural amino acids lead to the Krebs cycle. However, only nitrogen-free acyclic compounds can enter the Krebs cycle. In animals, however, the products of deamination and decyclization of amino acids are not only oxidized to end products in the Krebs cycle, but are also converted to glucose and ketone bodies. Consequently, every natural amino acid has a glucogenic or ketogenic effect, and some amino acids have a glucoketogenic or mixed effect, because they form both a glucogenic and a ketogenic product in the process of degradation. Tryptophan is such an amino acid. O
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2

Huang, Huawen, Kun Deng, and Guo-Jun Deng. "Redox-neutral decarboxylative photocyclization of anthranilic acids." Green Chemistry 22, no. 23 (2020): 8243–47. http://dx.doi.org/10.1039/d0gc02789h.

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3

Li, Yiming, Yuhong Wang, Tilong Yang, Zhenyang Lin, and Xuefeng Jiang. "Selenium-catalyzed intramolecular atom- and redox-economical transformation of o-nitrotoluenes into anthranilic acids." Green Chemistry 23, no. 8 (2021): 2986–91. http://dx.doi.org/10.1039/d0gc04407e.

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4

Proisl, Karel, Stanislav Kafka, Damijana Urankar, Martin Gazvoda, Roman Kimmel та Janez Košmrlj. "Fischer indolisation of N-(α-ketoacyl)anthranilic acids into 2-(indol-2-carboxamido)benzoic acids and 2-indolyl-3,1-benzoxazin-4-ones and their NMR study". Org. Biomol. Chem. 12, № 47 (2014): 9650–64. http://dx.doi.org/10.1039/c4ob01714e.

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5

Yang, Yajun, Cuiju Zhu, Min Zhang, et al. "Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization." Chemical Communications 52, no. 87 (2016): 12869–72. http://dx.doi.org/10.1039/c6cc07365d.

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6

Feigel, Martin, Gerhard Lugert, Javier Manero, and Matthias Bremer. "Konformation von Anthranilsäurepeptiden: Kristallstruktur von tert-Butyloxycarbonyl-Anthranilsäure-Glycinmethylester und semiempirische (AM 1) Beschreibung der Ramachandran-Hyperfläche / Conformation of Anthranilic Acid Peptides: Crystal Structure of tert-Butyloxycarbonyl-Anthranilic-Acid-Glycin-Methyl-Ester and Semi-Empirical (AM 1) Description of the Ramachandran Map." Zeitschrift für Naturforschung B 44, no. 9 (1989): 1109–16. http://dx.doi.org/10.1515/znb-1989-0919.

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Two different molecules are observed in the asymmetric unit of the crystal structure of tert-butyloxycarbonyl-anthranilic-acid-glycin-methyl-ester (1). The whole conformational area (φ and ψ) of the amino acid part of 1 was investigated with the semi-empirical quantenmechanical method AM 1. The structures of 1 in the crystal are well described by the calculations. Rules are derived for the conformational space of peptides containing esters and anthranilic acids.
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7

Abe, Takumi, Koshiro Kida, and Koji Yamada. "A copper-catalyzed Ritter-type cascade via iminoketene for the synthesis of quinazolin-4(3H)-ones and diazocines." Chemical Communications 53, no. 31 (2017): 4362–65. http://dx.doi.org/10.1039/c7cc01406f.

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8

Liermann, Johannes C., Eckhard Thines, Heidrun Anke, and Till Opatz. "Anthranicine, an Unusual Cyclic Hexapeptide from Acremonium sp. A29-2004." Zeitschrift für Naturforschung B 64, no. 6 (2009): 727–30. http://dx.doi.org/10.1515/znb-2009-0619.

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Anthranicine, a cyclic hexapeptide containing anthranilic acid and pipecolic acid, was isolated from a mycophilic Acremonium species. The structure and stereochemistry of the compound featuring two D-configurated amino acids are discussed.
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9

Faïon, Léo, Kamel Djaout, Catalin Pintiala, et al. "Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification." Pharmaceuticals 16, no. 3 (2023): 335. http://dx.doi.org/10.3390/ph16030335.

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Mycobacterium tuberculosis, the pathogen that causes tuberculosis, is responsible for the death of 1.5 million people each year and the number of bacteria resistant to the standard regimen is constantly increasing. This highlights the need to discover molecules that act on new M. tuberculosis targets. Mycolic acids, which are very long-chain fatty acids essential for M. tuberculosis viability, are synthesized by two types of fatty acid synthase (FAS) systems. MabA (FabG1) is an essential enzyme belonging to the FAS-II cycle. We have recently reported the discovery of anthranilic acids as MabA
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10

NISHIMURA, Jun, Satoshi MACHIN, Yoshikazu MIYAKE, Atsumi OKADA, Masaaki TERAMOTO, and Akira OKU. "Extraction of heavy metal ions by alkylated anthranilic acids." NIPPON KAGAKU KAISHI, no. 2 (1988): 230–35. http://dx.doi.org/10.1246/nikkashi.1988.230.

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11

Rong, Nianxin, Yongsheng Yuan, Huijie Chen, et al. "A practical route to 2-iodoanilines via the transition-metal-free and base-free decarboxylative iodination of anthranilic acids under oxygen." Organic Chemistry Frontiers 8, no. 16 (2021): 4479–84. http://dx.doi.org/10.1039/d1qo00461a.

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A new approach for synthesizing 2-iodoanilines via the transition-metal-free and base-free decarboxylative ortho-C–H iodination of anthranilic acids with a combination of KI and I<sub>2</sub> as the halogen donor and catalyst under oxygen has been developed.
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12

Slobodianiuk, Oksana, Oleksandra Berezhnytska, Tetyana Kamens'ka, and Мария Русакова. "SYNTHESIS AND PROPERTIES OF NEW N-ACYL DERIVATIVES OF ANTHRANILIC ACID." Ukrainian Chemistry Journal 85, no. 4 (2019): 59–70. http://dx.doi.org/10.33609/0041-6045.85.4.2019.59-70.

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A series of N-acyl derivatives of anthranil (or o -aminobenzoic acid) was first synthesized, namely 2-(4-octylbenzamido)benzoic acid, 2-(4-(heptyloxy)- benzamido)benzoic acid, 2-(4-(heptylsulfanyl)benz-amido)benzoic acid. 2-(4-octylbenzamido)benzoic acid was synthesized in five stages of octylbenzene, by acylating chloride acid using a Friedie-Crafts reaction. 2-(4-(heptyloxy)benzamido)benzoic acid was prepared from the methyl ester of p-hydroxybenzoic acid which, at the first stage, was activated with 1-bromoheptane in acetonitrile with potassium carbonate and catalytic amount of sodium iodid
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13

Paisidis, Polinikis, Maroula G. Kokotou, Antigoni Kotali, George Psomas, and Konstantina C. Fylaktakidou. "One-Pot, Multi-Component Green Microwave-Assisted Synthesis of Bridgehead Bicyclo[4.4.0]boron Heterocycles and DNA Affinity Studies." International Journal of Molecular Sciences 25, no. 18 (2024): 9842. http://dx.doi.org/10.3390/ijms25189842.

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Anthranilic acids, salicylaldehydes and arylboronic acids reacted in EtOH/H2O (1/3) at 150 °C under microwave irradiation for 1 h to give, in excellent yields and purity, twenty-three bridgehead bicyclo[4.4.0]boron heterocycles via one-pot, three-component green synthesis. The scope and the limitations of the reactions are discussed in terms of the substitution of ten different anthranilic acids, three salicylaldehydes and three arylboronic acids. The replacement of salicylaldehyde with o-hydroxyacetophenone demanded a lipophilic solvent for the reaction to occur. Eight novel derivatives were
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14

A. AL-Hadedi, Azam, and Rafid K. Jameel. "Synthesis and Cyclization of some N-(2-Pyridyl) Anthranilic Acids." Rafidain Journal of Science 21, no. 8 (2010): 19–29. http://dx.doi.org/10.33899/rjs.2010.36807.

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15

Wiklund, Per, Ivan Romero, and Jan Bergman. "Products from dehydration of dicarboxylic acids derived from anthranilic acid." Organic & Biomolecular Chemistry 1, no. 19 (2003): 3396. http://dx.doi.org/10.1039/b306032b.

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16

Wu, Yinuo, Cheng Jiang, Deyan Wu, Qiong Gu, Zhang-Yi Luo, and Hai-Bin Luo. "Palladium-catalyzed C–H bond carboxylation of acetanilides: an efficient usage of N,N-dimethyloxamic acid as the carboxylate source." Chemical Communications 52, no. 6 (2016): 1286–89. http://dx.doi.org/10.1039/c5cc07890c.

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A palladium-catalyzed carboxylation of acetanilide and N,N-dimethyloxamic acid for the synthesis of N-acyl-anthranilic acids is described. N,N-Dimethyloxamic acid can act as an effective carboxylation precursor with K<sub>2</sub>S<sub>2</sub>O<sub>8</sub> as the oxidant and Pd(OAc)<sub>2</sub> as the catalyst.
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17

M., IMTIAZ HUSAIN, and AMIR MOHD. "Synthesis of some New 2-Methyl-3-(2-methoxy-4-arylthiocarbamidophenyl)-6,8-substituted-4- quinazolones as Possible Anticonvulsants." Journal of Indian Chemical Society Vol. 62, Jun 1985 (1985): 468–70. https://doi.org/10.5281/zenodo.6319719.

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Chemistry Department, Lncknow University, Lncknow-216 007 <em>Manuscript received 21 April 1984, revised 26 December 1984, accepted 8 June 1985</em> In view of their expected M. A.O. inhibitory, C.N.S. depressant and anticon&shy;vulsant properties, twenty-one new 2-methyl-3-(2-methoxy-4-aryithiocarbamidophenyl)- 6,8-substituted-4-quinazolones were synthesised. Some of these compounds inhibited rat brain monoamineoxidase (in vitro) at a concentration 1 x 10<sup>-3</sup>&nbsp;mol dm<sup>2</sup>&nbsp;and pro&shy;duced protection against pentylenetetrazole-induced convulsions in mice.
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18

RIO, GABRIEL F., BÁRBARA V. SILVA, SABRINA T. MARTINEZ, and ANGELO C. PINTO. "Anthranilic acids from isatin: an efficient, versatile and environmentally friendly method." Anais da Academia Brasileira de Ciências 87, no. 3 (2015): 1525–29. http://dx.doi.org/10.1590/0001-3765201520140289.

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This paper describes the preparation of a series of 16 anthranilic acids in yields ranging from 51 to 97%, by treating the isatins with NaOH and H2O2. Independently of the nature of the substituent on the aromatic ring, the reactions were complete in 15 min at room temperature, whereas those of isatins containing a substituent on the nitrogen atom required longer reaction time for completion (45 min) under the same reaction conditions.
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19

Xie, Yuanyuan, and Suping Wang. "PhI(OAc)2-Mediated One-Pot Synthesis of Benzoxazinones from Anthranilic Acids and Aromatic Aldehydes." Journal of Chemical Research 36, no. 3 (2012): 123–26. http://dx.doi.org/10.3184/174751912x13285455672357.

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A novel way to synthesise 2-aryl-4H-benzo[d][1,3]oxazin-4-ones has been developed by the cyclisation of Schiff bases with (diacetoxyiodo)benzene. The salient features of this new protocol which starts from an anthranilic acid and an aromatic aldehyde, are short reaction time, mild reaction conditions and good yields.
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20

Abd El-Salam, N. M., Z. Y. Al Shoaibi, and G. A. Ahmed. "Chemical Studies on 3,6-Dichloropyridazine (Part 2)." E-Journal of Chemistry 8, no. 4 (2011): 1944–50. http://dx.doi.org/10.1155/2011/612825.

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3,6-Dichloropyridazine (1) reacted with 2-aminophenol, phenylalanine, acetophenone hydrazone derivatives, acid hydrazide derivatives and amino-aromatic acids (anthranilic acid and 5-bromoanthranilic acid) and yield the compounds (2), (3), (4a,b), (5a,b) and (6a,b) respectively. Reaction of compounds (5a,b) with acid hydrazide gave (8a,b). Also, compounds (6a,b) reacted with aromatic amino acid and gave (7a-c).
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21

Rudzite, Vera, Edite Jurika, Bernhard Widner, and Dietmar Fuchs. "Similarity Between the Action of Pteridines and Tryptophan Metabolites on Lipid Metabolism." Pteridines 10, no. 3 (1999): 133–40. http://dx.doi.org/10.1515/pteridines.1999.10.3.133.

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Abstract Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate, Krebs-Ringer-phosphate buffer (pH=7.4) containing 0.3% albumin, fatty acid mixture and glycerol. The addition of anthranilic acid (2.2 and 4 nmol/g wet weight), kynurenic acid (4 and 40 nmol/ g wet weight), xanthurenic acid (4 and 40 nmol/g wet weight), picolinic acid (0.2 and 2 nmol/g wet weight) induced an increase of saturated and a decrease of polyunsaturated fatty acids incorporation into phospholipids as well as an eleyation of choksterol concentration in samples u
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22

Potikha, L. M., V. A. Kovtunenko, and V. M. Kisil. "Condensed isoquinolines. 21. Condensation of o-bromomethylphenylacetonitrile with substituted anthranilic acids." Chemistry of Heterocyclic Compounds 43, no. 4 (2007): 460–69. http://dx.doi.org/10.1007/s10593-007-0066-1.

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23

Qiao, Xiaoxin, Douglas M. Ho, and Robert A. Pascal. "The Carbazole Connection: Unusual Products from the Diazotization of Anthranilic Acids." Journal of Organic Chemistry 61, no. 19 (1996): 6748–50. http://dx.doi.org/10.1021/jo960949x.

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24

van Veldhoven, Jacobus P. D., Rongfang Liu, Stephanie A. Thee, et al. "Affinity and kinetics study of anthranilic acids as HCA2 receptor agonists." Bioorganic & Medicinal Chemistry 23, no. 14 (2015): 4013–25. http://dx.doi.org/10.1016/j.bmc.2015.02.018.

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25

Jagadeesh, R. V., Puttaswamy, Nirmala Vaz, and N. M. Made Gowda. "Ruthenium catalyzed oxidative conversion of isatins to anthranilic acids: Mechanistic study." AIChE Journal 54, no. 3 (2008): 756–65. http://dx.doi.org/10.1002/aic.11416.

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26

Miltojevic, Ana, and Niko Radulovic. "Complete assignment of 1H- and 13C-NMR spectra of anthranilic acid and its hydroxy derivatives and salicylic acid and its amino derivatives." Facta universitatis - series: Physics, Chemistry and Technology 13, no. 2 (2015): 121–32. http://dx.doi.org/10.2298/fupct1502121m.

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We report on the detailed NMR spectral analyses of amino- or/and hydroxy-substituted benzoic acids: anthranilic (AA), 3-hydroxyanthranilic (3-HAA), 5-hydroxyanthranilic (5-HAA), salicylic (SA), 4-aminosalicylic (4-ASA) and 5-aminosalicylic (5-ASA) acids. According to a literature survey, there are limited, unassigned or even incorrectly assigned spectral data to these benzoic acid derivatives. In order to amend the situation, a complete assignment of 1H- and 13C-NMR spectra of these compounds, recorded in perdeuteriodimethyl sulfoxide (DMSO-d6), based on a combination of 1D- and 2D-NMR experim
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27

G., N. Mukherjee, Das Ansuman, and Bandyopadhyay Susmita. "Complex formation equilibria of Felll with boric acid in presence of some aminopolycarboxylic acids." Journal of Indian Chemical Society Vol. 81, Apr 2004 (2004): 282–86. https://doi.org/10.5281/zenodo.5830682.

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Department of Chemistry, University of Calcutta, University College of Science, 92, Acharya Prafulla Chandra Road, Kolkata-700 009, India <em>E-mail </em>: gmchem@rediffmail.com&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <em>&nbsp;Fax</em> : 91-33-23519755 <em>Manuscript received 7 January 2003, accepted 14 October 2003</em> Equilibrium study on the mixed ligand complex formation of Fe<sup>III</sup>&nbsp;with nitrilotriacetic acid and anthranilic acid diacetic acid (H<sub>3</sub>L) in the absence and in the presence of boric acid in different molar ratios provide the evidence of formation of Fe(L) Fe(O
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28

Komar, Mario, Tatjana Gazivoda Kraljević, Igor Jerković, and Maja Molnar. "Application of Deep Eutectic Solvents in the Synthesis of Substituted 2-Mercaptoquinazolin-4(3H)-Ones: A Comparison of Selected Green Chemistry Methods." Molecules 27, no. 2 (2022): 558. http://dx.doi.org/10.3390/molecules27020558.

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In this study, deep eutectic solvents (DESs) were used as green and eco-friendly media for the synthesis of substituted 2-mercaptoquinazolin-4(3H)-ones from different anthranilic acids and aliphatic or aromatic isothiocyanates. A model reaction on anthranilic acid and phenyl isothiocyanate was performed in 20 choline chloride-based DESs at 80 °C to find the best solvent. Based on the product yield, choline chloride:urea (1:2) DES was found to be the most effective, while DESs acted both as solvents and catalysts. Desired compounds were prepared with moderate to good yields using stirring, micr
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29

Jentsch, Nicholas G., Jared D. Hume, Emily B. Crull, et al. "Quinolines from the cyclocondensation of isatoic anhydride with ethyl acetoacetate: preparation of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate and derivatives." Beilstein Journal of Organic Chemistry 14 (September 28, 2018): 2529–36. http://dx.doi.org/10.3762/bjoc.14.229.

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A convenient two-step synthesis of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate derivatives has been developed starting from commercially available 2-aminobenzoic acids. In step 1, the anthranilic acids are smoothly converted to isatoic anhydrides using solid triphosgene in THF. In step 2, the anhydride electrophiles are reacted with the sodium enolate of ethyl acetoacetate, generated from sodium hydroxide, in warm N,N-dimethylacetamide resulting in the formation of substituted quinolines. A degradation–build-up strategy of the ethyl ester at the 3-position allowed for the construction of t
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30

Ruediger, Edward H., Sham S. Gandhi, Martin S. Gibson, Dan Fărcaşiu, and Cornelia Uncuţa. "Schmidt reaction of some constrained aromatic acids, and related topics." Canadian Journal of Chemistry 64, no. 3 (1986): 577–79. http://dx.doi.org/10.1139/v86-093.

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Schmidt reaction of phthalic acid in 90–98% sulfuric acid gives anthranilic acid and anthranilazide (major products) by a process considered to involve 3,1-benzoxazin-2,4(1H)-dione as intermediate. Benzimidazol-2-one is produced in this reaction by a secondary process from anthranilazide; it is also produced by photolysis of anthranilazide. Under Schmidt reaction conditions, 1,2,3-benzotriazin-4(3H)-one gives o-azidobenzamide. Under similar conditions, the lactol of 4-formyl-5-phenanthroic acid gives 1-azapyren-2(1H)-one and phenanthrene-4,5-dicarboximide, while phenanthrene-4,5-dicarboxylic a
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31

Yeromina, Hanna, Olena Sviechnikova, Lina Perekhoda, and Irina Sych. "Acid-base properties of substituted 6-nitro-N-(R-phenyl)anthranilic acids." Scripta Scientifica Pharmaceutica 2, no. 1 (2015): 49. http://dx.doi.org/10.14748/ssp.v1i1.1009.

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32

Niemann, G., and K. Versluis. "Anthranilic Acid Derivatives and Other Phenolic Acids from Fungus-Infected Carnation Stems." Planta Medica 56, no. 06 (1990): 564. http://dx.doi.org/10.1055/s-2006-961154.

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33

Hikawa, Hidemasa, and Yuusaku Yokoyama. "Palladium-Catalyzed Benzylation of Unprotected Anthranilic Acids with Benzyl Alcohols in Water." Organic Letters 13, no. 24 (2011): 6512–15. http://dx.doi.org/10.1021/ol2028042.

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34

Koay, Natalie, and Louis-Charles Campeau. "Efficient preparation of 3-substituted quinazolinediones directly from anthranilic acids and isocyanates." Journal of Heterocyclic Chemistry 48, no. 2 (2010): 473–78. http://dx.doi.org/10.1002/jhet.551.

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35

Bimal, Prasad Sharma, Lakhan Ram, and N. Singh B. "Synthesis of some new thioquinazolinone derivatives of biological activity." Journal of Indian Chemical Society Vol. 82, Jul 2005 (2005): 651–53. https://doi.org/10.5281/zenodo.5830554.

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M. M. A. M. Campus. Tribhuvan University, Biratnagar. Nepal <em>E-mail</em>: bimalbpsharma@rediffmail.com&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<em> Fax</em>: 977-21-26791 Department of Chemistry, Banaras Hindu University, Varanasi-221 005, India <em>Manuscript received 13 February 2003, revised 13 August 2004, accepted 22 March 2005</em> Twenty thioquinazolinone derivatives were prepared by the reaction of ammonium aryldithiocarbamate and appropriately substituted anthranilic acids of which seventeen are new. Their antibacterial and antifungal activities have been evalu
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36

Xin, Dongyue, and Kevin Burgess. "Anthranilic acid-containing cyclic tetrapeptides: at the crossroads of conformational rigidity and synthetic accessibility." Organic & Biomolecular Chemistry 14, no. 22 (2016): 5049–58. http://dx.doi.org/10.1039/c6ob00693k.

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37

Clegg, William, Mark R. J. Elsegood, and Carl Redshaw. "Extended Hydrogen-Bonded Molybdenum Arrays Derived from Carboxylic Acids and Dianilines: ROP Capability of the Complexes and Parent Acids and Dianilines." Catalysts 14, no. 3 (2024): 214. http://dx.doi.org/10.3390/catal14030214.

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From reactions involving sodium molybdate and dianilines [2,2′-(NH2)C6H4]2(CH2)n (n = 0, 1, 2) and amino-functionalized carboxylic acids 1,2-(NH2)(CO2H)C6H4 or 2-H2NC6H3-1,4-(CO2H)2, in the presence of Et3N and Me3SiCl, products adopting H-bonded networks have been characterized. In particular, the reaction of 2,2′-diaminobiphenyl, [2,2′-NH2(C6H4)]2, and 2-aminoterephthalic acid, H2NC6H3-1,4-(CO2H)2, led to the isolation of [(MoCl3[2,2′-N(C6H4)]2}{HNC6H3-1-(CO2),4-(CO2H)]·2[2,2′-NH2(C6H4)]2·3.5MeCN (1·3.5MeCN), which contains intra-molecular N–H∙∙∙Cl H-bonds and slipped π∙∙∙π interactions. Sim
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38

R., S. Panda, and Ch. Pradhan Subas. "Peroxy acid oxidation : A kinetic and mechanistic study of oxidation of aminobenzoic acids by peroxomonosulfuric acid." Journal of Indian Chemical Society Vol. 77, Jul 2000 (2000): 315–18. https://doi.org/10.5281/zenodo.5867079.

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Department of Chemistry, Khallikote College (Autonomous), Berhampur-760 001, India <em>Manuscript received 1&nbsp;march&nbsp;1999, revised 27 December 1999, accepted 3 March&nbsp;2000</em> The kinetics of oxidation of anthranilic acid and <em>p</em>-aminobenzoic acid by peroxomonosulfuric acid have been studied in aqueous medium in the pH range 0-6.4 at 308 K. The reactions are second order - first order each in pcroxy acid and in aminobenzoic acid concentration at constant pH. The reactivity of different peroxo species in the oxidation, has been determined. A mechanism consistent with rate-de
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39

Patel, Bhavesh, Ranjan Patel, and Manish Patel. "Synthesis and studies of the biological activity of novel pyrimido fused acridine derivatives." Journal of the Serbian Chemical Society 71, no. 10 (2006): 1015–23. http://dx.doi.org/10.2298/jsc0610015p.

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Anthranilic acid was reacted with various substituted 6-bromoquinazolinones in the presence of Cu-powder and anhydrous potassium carbonate in DMF to give acid intermediates (Ullmann Type-II condensation). All these acids were then cyclized in phosphorus oxychloride to give 11-chloropyrimido[4,5-b]acridin-4(3H)-ones. All the synthesized compounds were identified by conventional methods (1H-NMR, IR, elemental analysis) and were screened for their antimicrobial activity on some bacterial and fungal cultures. The results were compared with standard bactericides and fungicides. All the synthesized
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40

Best, WM, and D. Wege. "Intramolecular Diels-Alder Additions of Benzynes to Furans. Exploratory Studies." Australian Journal of Chemistry 39, no. 4 (1986): 635. http://dx.doi.org/10.1071/ch9860635.

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A series of 3-alkoxyanthranilic acids, in which a furan ring is attached to the terminal carbon atom of the alkoxy group, has been prepared. When the chain linking the anthranilic acid and furan ring systems is three or four atoms long, decomposition of the derived diazonium chlorides generates the corresponding benzynes , which are efficiently trapped intramolecularly by the furan moiety. Diazotization of 2-amino-3-furfuryloxybenzoic acid, where the linking chain is two atoms long, results in fragmentation with the formation of 6-diazo-5- oxocyclohexa-1,3-diene-1-carboxylic acid.
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41

Cao, Sheng-Li, Mei Zhang, Yu-Ping Feng, Yu-Yang Jiang, and Nan Zhang. "Synthesis of 3-Aryl-4(3H)-quinazolinones from Anthranilic Acids and Triethyl Orthoformate." Synthetic Communications 38, no. 13 (2008): 2227–36. http://dx.doi.org/10.1080/00397910802026584.

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42

Yadav, Lal, Atul Singh, and Ruchi Chawla. "Click Reaction of Epoxides with Anthranilic Acids Using Neat Grinding To Access Benzoxazepines." Synthesis 44, no. 15 (2012): 2353–58. http://dx.doi.org/10.1055/s-0031-1290988.

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43

Aiello, Francesca, Antonio Garofalo, and Fedora Grande. "Convenient synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids." Tetrahedron Letters 52, no. 44 (2011): 5824–26. http://dx.doi.org/10.1016/j.tetlet.2011.08.139.

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44

Aversa, M. C., P. Bonaccorsi, and P. Giannetto. "Chemical behaviour ofN-(2-hydroxybenzyl)anthranilic acids in the presence of acyclic anhydrides." Journal of Heterocyclic Chemistry 26, no. 5 (1989): 1383–87. http://dx.doi.org/10.1002/jhet.5570260528.

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45

Karthikeyan, P., Rajenahally V. Jagadeesh, Y. Sree Sandhya, et al. "Catalysis and mechanistic studies of ruthenium and osmium on synthesis of anthranilic acids." Applied Organometallic Chemistry 25, no. 1 (2010): 34–46. http://dx.doi.org/10.1002/aoc.1685.

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46

Gao, Yang, Jianhong Nie, Yibiao Li, Guilan Liao, Yanping Huo, and Xiao‐Qiang Hu. "Rh(III)‐Catalyzed Selective ortho ‐C−H Amination of Benzoic Acids with Anthranils: A Facile Access to Anthranilic Acid Derivatives (AAs)." ChemCatChem 12, no. 10 (2020): 2721–25. http://dx.doi.org/10.1002/cctc.202000052.

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47

Ng, Ka-Ho, Fo-Ning Ng, and Wing-Yiu Yu. "A convenient synthesis of anthranilic acids by Pd-catalyzed direct intermolecular ortho-C–H amidation of benzoic acids." Chemical Communications 48, no. 95 (2012): 11680. http://dx.doi.org/10.1039/c2cc36502b.

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48

Jagadeesh, R. "Mechanistic investigations of oxidation of isatins by sodium N-chlorobenzenesulfonamide in alkaline medium: A kinetic study." Open Chemistry 3, no. 3 (2005): 482–501. http://dx.doi.org/10.2478/bf02479277.

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AbstractOxidation of isatins (isatin, 5-methylisatin, 5-bromoisatin and 5-nitroisatin) to their anthranilic acids was performed efficiently with sodium N-chlorobenzenesulfonamide or chloramine-B (CAB) in alkaline medium at 35±0.1°C. The reactions follow identical kinetics for all the isatins, being first-order dependence each in [CAB]o and [Isatin]o and inverse fractional-order on [NaOH]. Addition of halide ions and benzenesulfonamide, reduction product of CAB, do not significantly affect the rate. Variation of ionic strength of the medium had no effect on the rate, while the dielectric effect
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Isaev, S. G., O. M. Sviechnikova, A. O. Devyatkina, T. A. Kostina, and T. N. Svyatska. "Reactivity of phenylanthranilic acids derivatives. Xxiii. Synthesis and acid-base properties of 4,5-dymethoxy-n-(2´-carboxyphenyl)anthranilic acids." Journal of Organic and Pharmaceutical Chemistry 11, no. 3(43) (2013): 26–31. http://dx.doi.org/10.24959/ophcj.13.748.

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Fritzson, Ingela, Bo Svensson, Salam Al-Karadaghi, et al. "Inhibition of Human DHODH by 4-Hydroxycoumarins, Fenamic Acids, andN-(Alkylcarbonyl)anthranilic Acids Identified by Structure-Guided Fragment Selection." ChemMedChem 5, no. 4 (2010): 608–17. http://dx.doi.org/10.1002/cmdc.200900454.

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