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Journal articles on the topic 'Anthraquinone Derivative'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Anderson, Benjamin R., and Mark G. Kuzyk. "Imaging studies of photodegradation and self-healing in anthraquinone derivative dye-doped PMMA." Physical Chemistry Chemical Physics 22, no. 48 (2020): 28154–64. http://dx.doi.org/10.1039/d0cp05426g.

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We compare the photodegradation and self-healing properties of nine anthraquinone derivatives doped into PMMA using transmission imaging. The results suggests “rules-of-thumb” to predict enhanced photostability and self-healing for anthraquinones.

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2

Caballero, Ana B., Nikolas J. Hodges, and Michael J. Hannon. "Folate-Receptor-Targeted Gold Nanoparticles Bearing a DNA-Binding Anthraquinone." Inorganics 13, no. 3 (2025): 87. https://doi.org/10.3390/inorganics13030087.

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In recent years, anthraquinones have been widening their therapeutic opportunities given their numerous health benefits. The search for adequate delivery platforms to improve their pharmacokinetics leads us to propose herein folate-capped gold nanoparticles with an anthraquinone derivative attached onto their surface. Through a straightforward, two-step procedure, we obtained stable nanoparticles that can deliver anthraquinones selectively to cells overexpressing folate receptors. The new conjugates were highly toxic against two tumour cell lines, lung carcinoma A549 and cervical carcinoma HeL

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3

Li, Xin, Xiao-Ming Li, and Bin-Gui Wang. "Structural Revision of Wentiquinone C and Related Congeners from Anthraquinones to Xanthones Using Chemical Derivatization and NMR Analysis." Marine Drugs 17, no. 1 (2018): 8. http://dx.doi.org/10.3390/md17010008.

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Wentiquinone C, which was previously isolated from the marine brown alga-derived endophytic fungus Aspergillus wentii EN-48, was found to be a potent antioxidant against α,α-diphenyl-picrylhydrazyl (DPPH) radical. The structure of wentiquinone C was originally assigned as an anthraquinone derivative (1,10-dihydroxy-3-(hydroxymethyl)-8-methoxydibenzo [b,e]oxepine-6,11-dione, 1) by 1D and 2D NMR experiments. However, the minor differences of the chemical shifts between xanthones and anthraquinones were queried, leading to the structure of 1 to be revised as a xanthone analog (8-hydroxy-6-(hydrox

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4

Rehman, ATA Ur, Shahid Ali, Safyan Akram Khan, and Muhammad Mansha. "Tuning the Performance of Anthraquinone-Derived Anolytes for AORFBS." ECS Meeting Abstracts MA2025-01, no. 45 (2025): 2416. https://doi.org/10.1149/ma2025-01452416mtgabs.

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Aqueous organic redox flow batteries (AORFBs) have garnered more recent interest because of their cost benignity, safety and suitable performance. In this regard, anthraquinone-based anolytes have proven capabilities under various conditions. Many derivatives of the anthraquinones have been opted to get an optimum performance for the low-cost redox flow batteries. Herein, we have first introduced a new derivative of the anthracenedione as an anolyte in the aqueous redox flow battery. The AORFB comprising 0.1 M of this anolyte, and coupled with the potassium hexaferrocyanide (0.2 M), has shown

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5

Ge, Xueping, Chunxiao Sun, Yanyan Feng, et al. "Anthraquinone Derivatives from a Marine-Derived Fungus Sporendonema casei HDN16-802." Marine Drugs 17, no. 6 (2019): 334. http://dx.doi.org/10.3390/md17060334.

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Five new anthraquinone derivatives, auxarthrols D–H (1–5), along with two known analogues (6–7), were obtained from the culture of the marine-derived fungus Sporendonema casei. Their structures, including absolute configurations, were established on the basis of NMR, HRESIMS, and circular dichroism (CD) spectroscopic techniques. Among them, compound 4 represents the second isolated anthraquinone derivative with a chlorine atom, which, with compound 6, are the first reported anthraquinone derivatives with anticoagulant activity. Compounds 1 and 3 showed cytotoxic activities with IC50 values fro

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6

Miki, Sadao, Hiroyuki Kagawa, and Zen-Ichi Yoshida. "Chemiexcitation of an anthraquinone derivative in the thermal cycloreversion of a dewar-anthraquinone derivative." Journal of Physical Organic Chemistry 5, no. 2 (1992): 101–3. http://dx.doi.org/10.1002/poc.610050206.

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7

Yang, Xiaowei, Yinhuan Zhang, Yan Liu, Chang Chen, Wenjuan Xu, and Hongbin Xiao. "Emodin induces liver injury by inhibiting the key enzymes of FADH/NADPH transport in rat liver." Toxicology Research 7, no. 5 (2018): 888–96. http://dx.doi.org/10.1039/c7tx00307b.

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8

Kazmi, Mehdi H., Abdul Malik, Saira Hameed, Nargis Akhtar, and Samina Noor Ali. "An anthraquinone derivative from Cassia italica." Phytochemistry 36, no. 3 (1994): 761–63. http://dx.doi.org/10.1016/s0031-9422(00)89812-x.

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9

Hosoe, Tomoo, Koohei Nozawa, Shun-ichi Udagawa, Shoichi Nakajima, and Ken-ichi Kawai. "An anthraquinone derivative from Dichotomophthora lutea☆." Phytochemistry 29, no. 3 (1990): 997–99. http://dx.doi.org/10.1016/0031-9422(90)80068-r.

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10

Zhao, Huan, Zhiqun He, Min Xu, Chunjun Liang, and Sandeep Kumar. "Electron transporting organic materials with an exceptional large scale homeotropic molecular orientation." Physical Chemistry Chemical Physics 18, no. 12 (2016): 8554–60. http://dx.doi.org/10.1039/c6cp00031b.

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11

Yamashita, Yu, Yoichi Hirano, Akiomi Takada, Hiroshi Takikawa, and Keisuke Suzuki. "Total Synthesis of Bis-anthraquinone Antibiotic BE-43472B." Synthesis 50, no. 13 (2018): 2490–515. http://dx.doi.org/10.1055/s-0037-1610136.

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This is a full account of our synthetic endeavor on the total synthesis of bis-anthraquinone antibiotic BE-43472B, an unusual octacyclic aromatic polyketide with a bis-anthraquinone scaffold. Three key steps enabled a facile access to the anthraquinone unit corresponding to the ABCF rings; (1) cyclo-condensation or -addition of benzonitrile oxides with cyclic enone derivatives, (2) benzoin cyclization for the stereoselective ring fusion with an angular hydroxy group, and (3) pinacol rearrangement for stereoselective installation of the angular aryl group. Other keys for the success include, (4

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12

Singh, Pahup, Sunita Jain, and Sangeeta Bhargava. "A 1,4-Anthraquinone derivative from Tectona grandis." Phytochemistry 28, no. 4 (1989): 1258–59. http://dx.doi.org/10.1016/0031-9422(89)80224-9.

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13

R., P. VERMA, K. AMBASTA B., PRASAD G., and K.S.SINHA. "Isolation and Characterisation of a New Anthraquinone Derivative from Cassia grandis Linn." Journal of Indian Chemical Society Vol. 74, May 1997 (1997): 428. https://doi.org/10.5281/zenodo.5909074.

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Department of Chemistry, Magadh University, Bodh-Gaya-824 234 <em>Manuscript received 19 September 1995, accepted 12 January 1996</em> Isolation and Characterisation of a New Anthraquinone Derivative from <em>Cassia grandis</em> Linn.

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14

Yu, Runnan, Xueqi Wei, Guangzheng Wu, et al. "Efficient interface modification via multi-site coordination for improved efficiency and stability in organic solar cells." Energy & Environmental Science 15, no. 2 (2022): 822–29. http://dx.doi.org/10.1039/d1ee03263a.

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An anthraquinone derivative is developed to modify the SnO2 interface in organic solar cells via the multi-site coordination effect, yielding outstanding photovoltaic performances and device stability.

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15

De Luchi, Daniela, Isabel Usón, Glenford Wright, Catherine Gouyette, and Juan A. Subirana. "Structure of a stacked anthraquinone–DNA complex." Acta Crystallographica Section F Structural Biology and Crystallization Communications 66, no. 9 (2010): 1019–22. http://dx.doi.org/10.1107/s1744309110030034.

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The crystal structure of the telomeric sequence d(UBrAGG) interacting with an anthraquinone derivative has been solved by MAD. In all previously studied complexes of intercalating drugs, the drug is usually sandwiched between two DNA base pairs. Instead, the present structure looks like a crystal of stacked anthraquinone molecules in which isolated base pairs are intercalated. Unusual base pairs are present in the structure, such as G·G and A·UBrreverse Watson–Crick base pairs.

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16

Nakagawa, Hidemi, and Chitoshi Kitamura. "Crystal structures of 1-hydroxy-4-propyloxy-9,10-anthraquinone and its acetyl derivative." Acta Crystallographica Section E Crystallographic Communications 73, no. 12 (2017): 1845–49. http://dx.doi.org/10.1107/s2056989017015973.

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1-Hydroxy-4-propyloxy-9,10-anthraquinone, C17H14O4, (I), and its acetyl derivative, 4-acetyloxy-4-propyloxy-9,10-anthraquinone, C19H16O5, (II), were synthesized from the commercially available dye quinizarin. In both compounds, the anthraquinone frameworks are close to planarity. There is a large difference in the conformation of the propyloxy group; the molecule of (I) adopts agaucheconformation [O—C—C—C = −64.4 (2)°], although the molecule of (II) takes atrans-planar conformation (zigzag) [O—C—C—C = 176.1 (3)°]. In the molecule of (I), there is an intramolecular O—H...O hydrogen bond. In bot

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17

Jing, Yan, Min Wu, Andrew A. Wong, et al. "In situ electrosynthesis of anthraquinone electrolytes in aqueous flow batteries." Green Chemistry 22, no. 18 (2020): 6084–92. http://dx.doi.org/10.1039/d0gc02236e.

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We demonstrate the electrochemical oxidation of an anthracene derivative to a redox-active anthraquinone at room temperature in a flow cell without the use of hazardous oxidants or noble metal catalysts.

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18

Goudappagouda, Aakash D. Nidhankar, Rashmi A. Nayak, and Sukumaran Santhosh Babu. "Aggregation-induced phosphorescence of an anthraquinone based emitter." Organic & Biomolecular Chemistry 19, no. 5 (2021): 1004–8. http://dx.doi.org/10.1039/d0ob02505d.

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Room temperature phosphorescence (RTP) of metal-free organic molecules is a hot topic of current research interest. In this work, aggregation drives a weakly emissive anthraquinone derivative to exhibit room temperature phosphorescence.

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19

Semwal, Ruchi Badoni, Deepak Kumar Semwal, Sandra Combrinck, and Alvaro Viljoen. "Emodin - A natural anthraquinone derivative with diverse pharmacological activities." Phytochemistry 190 (October 31, 2021): 1–20. https://doi.org/10.1016/j.phytochem.2021.112854.

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Semwal, Ruchi Badoni, Semwal, Deepak Kumar, Combrinck, Sandra, Viljoen, Alvaro (2021): Emodin - A natural anthraquinone derivative with diverse pharmacological activities. Phytochemistry (112854) 190: 1-20, DOI: 10.1016/j.phytochem.2021.112854, URL: http://dx.doi.org/10.1016/j.phytochem.2021.112854

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20

Kolesnichenko, Igor V., P. Rogelio Escamilla, Jason A. Michael, Vincent M. Lynch, David A. Vanden Bout, and Eric V. Anslyn. "Hydrogen peroxide production via a redox reaction of N,N′-dimethyl-2,6-diaza-9,10-anthraquinonediium by addition of bisulfite." Chemical Communications 54, no. 79 (2018): 11204–7. http://dx.doi.org/10.1039/c8cc05548c.

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We demonstrate that bisulfite can be used for reduction of a highly electrophilic anthraquinone derivative, N,N′-dimethyl-2,6-diaza-9,10-anthraquinonediium (DAAQ), and subsequent autoxidation generates an equivalent of hydrogen peroxide.

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21

Mahdy, Basyouny, Atef Fathi Ali, Hassan Mohammed Ibrahim, and Essam Eldin Abdelaziz Nada. "Effectiveness of hCG and Aromatase Inhibitors Before Micro TESE in Men with Non-Obstructive Azoospermia." Journal of Neonatal Surgery 14, no. 5S (2025): 716–27. https://doi.org/10.52783/jns.v14.2122.

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Diabetes mellitus, particularly type 2 diabetes, is a growing global health issue, often exacerbated by insulin resistance, metabolic disturbances, and inflammatory responses. Emodin, a natural anthraquinone derivative, has been widely recognized for its

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22

Malik, Enas M., Younis Baqi, and Christa E. Müller. "Syntheses of 2-substituted 1-amino-4-bromoanthraquinones (bromaminic acid analogues) – precursors for dyes and drugs." Beilstein Journal of Organic Chemistry 11 (November 26, 2015): 2326–33. http://dx.doi.org/10.3762/bjoc.11.253.

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Anthraquinone (AQ) derivatives play a prominent role in medicine and also in textile industry. Bromaminic acid (1-amino-4-bromoanthraquinone-2-sulfonic acid) is an important precursor for obtaining dyes as well as biologically active compounds through the replacement of the C4-bromo substituent with different (ar)alkylamino residues. Here we report methods for the synthesis of bromaminic acid analogues bearing different substituents at the 2-position of the anthraquinone core. 1-Aminoanthraquinone was converted to its 2-hydroxymethyl-substituted derivative which, under different reaction condi

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23

Girich, Elena V., Phan Thi Hoai Trinh, Liliana E. Nesterenko, et al. "Absolute Stereochemistry and Cytotoxic Effects of Vismione E from Marine Sponge-Derived Fungus Aspergillus sp. 1901NT-1.2.2." International Journal of Molecular Sciences 24, no. 9 (2023): 8150. http://dx.doi.org/10.3390/ijms24098150.

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The metabolic profile of the Aspergillus sp. 1901NT-1.2.2 sponge-associated fungal strain was investigated using the HPLC MS technique, and more than 23 peaks in the HPLC MS chromatogram were detected. Only two minor peaks were identified as endocrocin and terpene derivative MS data from the GNPS database. The main compound was isolated and identified as known anthraquinone derivative vismione E. The absolute stereochemistry of vismione E was established for the first time using ECD and quantum chemical methods. Vismione E showed high cytotoxic activity against human breast cancer MCF-7 cells,

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24

Keller, Gerwin, and Wolfgang Steglich. "4-aminophyscion, an anthraquinone derivative from dermocybe (Agaricales)." Phytochemistry 26, no. 7 (1987): 2119–21. http://dx.doi.org/10.1016/s0031-9422(00)81776-8.

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25

Schrader, Kevin K., N. P. Dhammika Nanayakkara, Craig S. Tucker, Agnes M. Rimando, Markus Ganzera, and Brian T. Schaneberg. "Novel Derivatives of 9,10-Anthraquinone Are Selective Algicides against the Musty-Odor Cyanobacterium Oscillatoria perornata." Applied and Environmental Microbiology 69, no. 9 (2003): 5319–27. http://dx.doi.org/10.1128/aem.69.9.5319-5327.2003.

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ABSTRACT Musty “off-flavor” in pond-cultured channel catfish (Ictalurus punctatus) costs the catfish production industry in the United States at least $30 million annually. The cyanobacterium Oscillatoria perornata (Skuja) is credited with being the major cause of musty off-flavor in farm-raised catfish in Mississippi. The herbicides diuron and copper sulfate, currently used by catfish producers as algicides to help mitigate musty off-flavor problems, have several drawbacks, including broad-spectrum toxicity towards the entire phytoplankton community that can lead to water quality deterioratio

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26

Çalış, Ihsan, S. Serap Birincioǧlu, Hasan Kırmızıbekmez, Bernhard Pfeiffer, and Jörg Heilmann. "Secondary Metabolites from Asphodelus aestivus." Zeitschrift für Naturforschung B 61, no. 10 (2006): 1304–10. http://dx.doi.org/10.1515/znb-2006-1019.

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Together with ten well known compounds, the quinic acid derivative chlorogenic acid, the nucleoside adenosine, two amino acids, tryptophan and phenylalanine, the anthraquinone derivatives, aloemodin, aloemodin acetate and chyrosphanol 1-O-gentiobioside, the flavon C-glycosides, isovitexin, isoorientin and isoorientin 4’-O-β -glucopyranoside, as well as two new acylated isoorientin derivatives, 6”-O-(malonyl)-isoorientin and 6”-O-[(S)-3-hydroxy-3-methylglutaroyl]-isoorientin, were isolated from the water soluble part of the methanolic extract of the fresh leaves of Asphodelus aestivus. All comp

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27

Amorim, Juliana Carolina, Andrea E. Cabrera Bermeo, Viviana E. Vásquez Urgilés, Maritza R. Martínez León, and Juan M. Carpio Arévalo. "An In-Silico Evaluation of Anthraquinones as Potential Inhibitors of DNA Gyrase B of Mycobacterium tuberculosis." Microorganisms 10, no. 12 (2022): 2434. http://dx.doi.org/10.3390/microorganisms10122434.

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The World Health Organization reported that tuberculosis remains on the list of the top ten threats to public health worldwide. Among the main causes is the limited effectiveness of treatments due to the emergence of resistant strains of Mycobacterium tuberculosis. One of the main drug targets studied to combat M. tuberculosis is DNA gyrase, the only enzyme responsible for regulating DNA topology in this specie and considered essential in all bacteria. In this context, the present work tested the ability of 2824 anthraquinones retrieved from the PubChem database to act as competitive inhibitor

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28

Ngo Nyobe, Judith Caroline, Laurent Gael Eyia Andiga, Désiré Bikele Mama, et al. "A DFT Analysis on Antioxidant and Antiradical Activities from Anthraquinones Isolated from the Cameroonian Flora." Journal of Chemistry 2019 (June 24, 2019): 1–13. http://dx.doi.org/10.1155/2019/7684941.

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The present work is devoted to the exploration antioxidant and antiradical activity of twenty anthraquinones isolated from the Cameroonian flora at B3LYP/6-311++G(d,p) level of theory using the B3LYP/6-31 + G(d,p) geometrical data as geometry optimization starting points. The single electron transfer mechanism has been adopted to examine both biological activities. The classification of the antiradical profile to integrate the electrodonating power (ω−), electroaccepting power (ω+), donor index (Rd) and acceptor index (Ra) has been performed using the donor-acceptor map (DAM). The antioxidant

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29

Hussain, Hidayat, Shahid Aziz, Barbara Schulz, and Karsten Krohn. "Synthesis of a 4H-anthra[1,2-b]pyran Derivative and its Antimicrobial activity." Natural Product Communications 6, no. 6 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600621.

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The five-step synthesis of the new 4 H-anthra[1,2- b]pyran derivative 1 is reported. The key steps in this approach included a Marschalk alkylation of 1,4-dihydroxyanthraquinone followed by a Baker–Venkataraman reaction and then an acid-catalyzed cyclization of ring A to form the 4H-anthra[1,2-b]pyran system. Two compounds, the 4H-anthra[1,2-b]pyran 1 and the anthraquinone derivative 6 were evaluated for antimicrobial activity and showed moderate antialgal, antifungal, and antibacterial activities.

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30

Semwal, Ruchi Badoni, Deepak Kumar Semwal, Sandra Combrinck, and Alvaro Viljoen. "Emodin - A natural anthraquinone derivative with diverse pharmacological activities." Phytochemistry 190 (October 2021): 112854. http://dx.doi.org/10.1016/j.phytochem.2021.112854.

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31

Srivastava, Sanjay, Arnab Roy Chowdhury, and Sudarshan Maurya. "Antimicrobial Efficacy of Methylated Lac Dye, an Anthraquinone Derivative." Indian Journal of Microbiology 57, no. 4 (2017): 470–76. http://dx.doi.org/10.1007/s12088-017-0682-0.

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32

Takenaka, Shigeori, Toshihiro Ihara, Masaru Hamano, and Makoto Takagi. "A zwitterionic anthraquinone derivative: first zwitterionic DNA binding ligand." Journal of the Chemical Society, Chemical Communications, no. 18 (1990): 1271. http://dx.doi.org/10.1039/c39900001271.

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33

AMBASTA, B. K., G. PRASAD, K. S. SINHA, and R. P. VERMA. "ChemInform Abstract: An Anthraquinone Derivative from Cassia grandis Linn." ChemInform 27, no. 47 (2010): no. http://dx.doi.org/10.1002/chin.199647255.

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34

HEMLATA, HEMLATA, and S. B. KALIDHAR. "ChemInform Abstract: Alatonal, an Anthraquinone Derivative from Cassia alata." ChemInform 25, no. 24 (2010): no. http://dx.doi.org/10.1002/chin.199424269.

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35

Shupenyuk, V. I., A. V. Lozynskyi, I. I. Ivasechko, et al. "BIOLOGICAL ACTIVITY OF ISOPROPYLAMINE ANTHRAQUINONE." Фармацевтичний часопис, no. 2 (June 28, 2024): 14–21. http://dx.doi.org/10.11603/2312-0967.2024.2.14820.

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The aim of the work. To predict the drug-likeness and toxicity using modern web tools of the isopropylaminoanthraquinone compound, as well as to experimentally prove a possible mechanism of antitumor activity. Materials and Methods. For the anthraquinone compound, an in silico drug-likeness and toxicity screening was performed using SwissADME and ProTox II online services. Prediction of the antitumor activity mechanism was analyzed using the US National Cancer Institute (NCI) PRISM service. Results and Discussion. 1-Amino-4-(isopropylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid was

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Kitajima, Showa, Hitoshi Kasai, and Kouki Oka. "Rechargeable Organic Molecule-Air Battery." ECS Meeting Abstracts MA2024-02, no. 67 (2024): 4464. https://doi.org/10.1149/ma2024-02674464mtgabs.

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[Introduction] The development of environmentally friendly batteries, such as rechargeable aqueous metal-air batteries, has been required for sustainable energy supply. Aqueous zinc-air batteries, composed of zinc as the anode, O2 in the air as the cathode, and a very base aqueous solution (e.g., 6 M KOH aqueous solution) as the electrolyte, are one of the representative environmentally friendly batteries, because of their high energy density (1353 W h kg−1 excluding oxygen) compared to conventional lithium-ion batteries (limited to be <350 W h kg−1 based on the intercalation chemistry).[1]

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Huang, S. W., J. C. Lien, S. C. Kuo, and T. F. Huang. "PPemd26, an anthraquinone derivative, suppresses angiogenesis via inhibiting VEGFR2 signalling." British Journal of Pharmacology 171, no. 24 (2014): 5728–42. http://dx.doi.org/10.1111/bph.12872.

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38

Yamada, Mami, Kenya Kubo, and Hiroshi Nishihara. "Electroreductive Deposition of Au Clusters Modified with an Anthraquinone Derivative." Chemistry Letters 28, no. 12 (1999): 1335–36. http://dx.doi.org/10.1246/cl.1999.1335.

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39

OZKOK, Funda, Demet SEZGIN MANSUROGLU, Pinar OZ, et al. "Synthesis of a novel thio-anthraquinone derivative-based tissue dye." Revue Roumaine de Chimie 69, no. 5-6 (2024): 301–7. http://dx.doi.org/10.33224/rrch.2024.69.5-6.08.

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In this study, a new dye, Neurange stain, was developed for histopathological examination of brain tissue using light microscopy. In addition, Neurange dye can be used in routine analyses and microscopic imaging of tissue sections. The synthesis of 1-(4-hydroxyphenylthio)anthracene-9,10-dione (3), a new thio-anthraquinone derivative used in the preparation of Neurange dye, began with the substitution reaction of 4-hydroxythiophenol (2) and 1-chloroanthraquinone (1) as starting materials.1 Neurange dye shows specific staining of white matter in brain tissue sections. It shows brown-orange stain

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40

CUI, Ya, Liu-Jing CHEN, Tu HUANG, Jian-Qiong YING, and Juan LI. "The pharmacology, toxicology and therapeutic potential of anthraquinone derivative emodin." Chinese Journal of Natural Medicines 18, no. 6 (2020): 425–35. http://dx.doi.org/10.1016/s1875-5364(20)30050-9.

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41

Halder, Raghunath, and Adeniyi Lawal. "Experimental studies on hydrogenation of anthraquinone derivative in a microreactor." Catalysis Today 125, no. 1-2 (2007): 48–55. http://dx.doi.org/10.1016/j.cattod.2007.03.055.

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42

Şeker Karatoprak, Gökçe, Esra Küpeli Akkol, Çiğdem Yücel, Özlem Bahadır Acıkara, and Eduardo Sobarzo-Sánchez. "Advances in Understanding the Role of Aloe Emodin and Targeted Drug Delivery Systems in Cancer." Oxidative Medicine and Cellular Longevity 2022 (January 18, 2022): 1–20. http://dx.doi.org/10.1155/2022/7928200.

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Cancer is one of the important causes of death worldwide. Despite remarkable improvements in cancer research in the past few decades, several cancer patients still cannot be cured owing to the development of drug resistance. Natural sources might have prominence as potential drug candidates. Among the several chemical classes of natural products, anthraquinones are characterized by their large structural variety, noticeable biological activity, and low toxicity. Aloe emodin, an anthraquinone derivative, is a natural compound found in the roots and rhizomes of many plants. This compound has pro

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43

Hwang, Yun-Ho, Su-Jin Kim, and Sung-Tae Yee. "Physcion-Matured Dendritic Cells Induce the Differentiation of Th1 Cells." International Journal of Molecular Sciences 21, no. 5 (2020): 1753. http://dx.doi.org/10.3390/ijms21051753.

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In addition to their use as colorants, anthraquinone derivatives have numerous medical applications, for example, as antibacterial and antiinflammatory agents. We confirmed that physcion (an anthraquinone derivative) induces TNF-alpha production by macrophages and increased the expressions of surface molecules (CD40, CD80, and CD86) and major histocompatibility complex (MHC) II. Based on these results, we hypothesized that physcion might induce the maturation of dendritic cells (DCs) to antigen-presenting cells (APCs), and decided to conduct in vitro experiments using bone-marrow-derived DCs (

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Huang, S. W., and T. F. Huang. "665 Anti-angiogenic Mechanisms of PPemd 26, a Novel Anthraquinone Derivative." European Journal of Cancer 48 (July 2012): S158. http://dx.doi.org/10.1016/s0959-8049(12)71311-4.

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Gheeya, Jinesh, Peter Johansson, Qing-Rong Chen, et al. "Expression profiling identifies epoxy anthraquinone derivative as a DNA topoisomerase inhibitor." Cancer Letters 293, no. 1 (2010): 124–31. http://dx.doi.org/10.1016/j.canlet.2010.01.004.

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Roman, Maciej, Agnieszka Kaczor, and Malgorzata Baranska. "Relationship between structure and entropy contributions in an anthraquinone mercapto derivative." Journal of Molecular Modeling 16, no. 10 (2010): 1549–57. http://dx.doi.org/10.1007/s00894-010-0654-3.

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Abdelfattah, Mohamed S. "Isolation and Crystal Structure of a new Anthraquinone Derivative from Actinomycete." Chemistry of Natural Compounds 50, no. 4 (2014): 613–16. http://dx.doi.org/10.1007/s10600-014-1036-3.

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Chen, Min, Chang-Lun Shao, Chui-Jian Kong, Zhi-Gang She, and Chang-Yun Wang. "A New Anthraquinone Derivative from a Gorgonian-Derived Fungus Aspergillus sp." Chemistry of Natural Compounds 50, no. 4 (2014): 617–20. http://dx.doi.org/10.1007/s10600-014-1037-2.

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Wilkinson, S. M., J. Brittain, and M. H. Beck. "Allergic contact dermatitis from an anthraquinone derivative in a chemical plant." Contact Dermatitis 30, no. 4 (1994): 241–42. http://dx.doi.org/10.1111/j.1600-0536.1994.tb00654.x.

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Shao, Changlun, Changyun Wang, Caijuan Zheng, Zhigang She, Yucheng Gu, and Yongcheng Lin. "A new anthraquinone derivative from the marine endophytic fungusFusariumsp. (No. b77)." Natural Product Research 24, no. 1 (2010): 81–85. http://dx.doi.org/10.1080/14786410902836701.

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