Log in

Relevant bibliographies by topics / Anti–σ factor Interactions / Journal articles

To see the other types of publications on this topic, follow the link: Anti–σ factor Interactions.

Journal articles on the topic 'Anti–σ factor Interactions'

Author: Grafiati

Published: 6 September 2023

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Anti–σ factor Interactions.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Jamithireddy, Anil Kumar, Ashish Runthala та Balasubramanian Gopal. "Evaluation of specificity determinants in Mycobacterium tuberculosis σ/anti-σ factor interactions". Biochemical and Biophysical Research Communications 521, № 4 (2020): 900–906. http://dx.doi.org/10.1016/j.bbrc.2019.10.198.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Shukla, Jinal, Radhika Gupta, Krishan Gopal Thakur, Rajesh Gokhale та B. Gopal. "Structural basis for the redox sensitivity of theMycobacterium tuberculosisSigK–RskA σ–anti-σ complex". Acta Crystallographica Section D Biological Crystallography 70, № 4 (2014): 1026–36. http://dx.doi.org/10.1107/s1399004714000121.

Full text

Abstract:

The host–pathogen interactions inMycobacterium tuberculosisinfection are significantly influenced by redox stimuli and alterations in the levels of secreted antigens. The extracytoplasmic function (ECF) σ factor σKgoverns the transcription of the serodominant antigens MPT70 and MPT83. The cellular levels of σKare regulated by the membrane-associated anti-σK(RskA) that localizes σKin an inactive complex. The crystal structure ofM. tuberculosisσKin complex with the cytosolic domain of RskA (RskAcyto) revealed a disulfide bridge in the −35 promoter-interaction region of σK. Biochemical experiment

APA, Harvard, Vancouver, ISO, and other styles

3

Kwak, Min-Kyu, Han-Bong Ryu, Sung-Hyun Song, Jin-Won Lee та Sa-Ouk Kang. "Anti-σ factor YlaD regulates transcriptional activity of σ factor YlaC and sporulation via manganese-dependent redox-sensing molecular switch in Bacillus subtilis". Biochemical Journal 475, № 13 (2018): 2127–51. http://dx.doi.org/10.1042/bcj20170911.

Full text

Abstract:

YlaD, a membrane-anchored anti-sigma (σ) factor of Bacillus subtilis, contains a HX3CXXC motif that functions as a redox-sensing domain and belongs to one of the zinc (Zn)-co-ordinated anti-σ factor families. Despite previously showing that the YlaC transcription is controlled by YlaD, experimental evidence of how the YlaC–YlaD interaction is affected by active cysteines and/or metal ions is lacking. Here, we showed that the Pyla promoter is autoregulated solely by YlaC. Moreover, reduced YlaD contained Zn and iron, while oxidized YlaD did not. Cysteine substitution in YlaD led to changes in i

APA, Harvard, Vancouver, ISO, and other styles

4

Anthony, Jennifer R., Jack D. Newman та Timothy J. Donohue. "Interactions Between the Rhodobacter sphaeroides ECF Sigma Factor, σ E , and its Anti-sigma Factor, ChrR". Journal of Molecular Biology 341, № 2 (2004): 345–60. http://dx.doi.org/10.1016/j.jmb.2004.06.018.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Wettstadt, Sarah, Francisco J. Marcos-Torres, Joaquín R. Otero-Asman, Alicia García-Puente, Álvaro Ortega та María A. Llamas. "Bacterial TonB-dependent transducers interact with the anti-σ factor in absence of the inducing signal protecting it from proteolysis". PLOS Biology 22, № 12 (2024): e3002920. https://doi.org/10.1371/journal.pbio.3002920.

Full text

Abstract:

Competitive bacteria like the human pathogen Pseudomonas aeruginosa can acquire iron from different iron carriers, which are usually internalized via outer membrane TonB-dependent receptors (TBDRs). Production of TBDRs is promoted by the presence of the substrate. This regulation often entails a signal transfer pathway known as cell-surface signaling (CSS) that involves the TBDR itself that also functions as transducer (and is thus referred to as TBDT), a cytoplasmic membrane-bound anti-σ factor, and an extracytoplasmic function σ (σECF) factor. TBDTs contain an extra N-terminal domain known a

APA, Harvard, Vancouver, ISO, and other styles

6

Cartagena, Alexis Jaramillo, Amy B. Banta, Nikhil Sathyan та ін. "Structural basis for transcription activation by Crl through tethering of σS and RNA polymerase". Proceedings of the National Academy of Sciences 116, № 38 (2019): 18923–27. http://dx.doi.org/10.1073/pnas.1910827116.

Full text

Abstract:

In bacteria, a primary σ-factor associates with the core RNA polymerase (RNAP) to control most transcription initiation, while alternative σ-factors are used to coordinate expression of additional regulons in response to environmental conditions. Many alternative σ-factors are negatively regulated by anti–σ-factors. In Escherichia coli, Salmonella enterica, and many other γ-proteobacteria, the transcription factor Crl positively regulates the alternative σS-regulon by promoting the association of σS with RNAP without interacting with promoter DNA. The molecular mechanism for Crl activity is un

APA, Harvard, Vancouver, ISO, and other styles

7

Thakur, Krishan Gopal, Anagha Madhusudan Joshi та B. Gopal. "Structural and Biophysical Studies on Two Promoter Recognition Domains of the Extra-cytoplasmic Function σ Factor σC from Mycobacterium tuberculosis". Journal of Biological Chemistry 282, № 7 (2006): 4711–18. http://dx.doi.org/10.1074/jbc.m606283200.

Full text

Abstract:

σ factors are transcriptional regulatory proteins that bind to the RNA polymerase and dictate gene expression. The extracytoplasmic function (ECF) σ factors govern the environment dependent regulation of transcription. ECF σ factors have two domains σ2 and σ4 that recognize the -10 and -35 promoter elements. However, unlike the primary σ factor σA, the ECF σ factors lack σ3, a region that helps in the recognition of the extended -10 element and σ1.1, a domain involved in the autoinhibition of σA in the absence of core RNA polymerase. Mycobacterium tuberculosis σC is an ECF σ factor that is ess

APA, Harvard, Vancouver, ISO, and other styles

8

Karlinsey, Joyce E., and Kelly T. Hughes. "Genetic Transplantation: Salmonella enterica Serovar Typhimurium as a Host To Study Sigma Factor and Anti-Sigma Factor Interactions in GeneticallyIntractable Systems." Journal of Bacteriology 188, no. 1 (2006): 103–14. http://dx.doi.org/10.1128/jb.188.1.103-114.2006.

Full text

Abstract:

ABSTRACT In Salmonella enterica serovar Typhimurium,σ 28 and anti-sigma factor FlgM are regulatory proteins crucial for flagellar biogenesis and motility. In this study, we used S. enterica serovar Typhimurium as an in vivo heterologous system to study σ28 and anti-σ28 interactions in organisms where genetic manipulation poses a significant challenge due to special growth requirements. The chromosomal copy of the S. enterica serovar Typhimurium σ28 structural gene fliA was exchanged with homologs of Aquifex aeolicus (an extreme thermophile) and Chlamydia trachomatis (an obligate intracellular

APA, Harvard, Vancouver, ISO, and other styles

9

Cavaliere, Paola, та Françoise Norel. "Recent advances in the characterization of Crl, the unconventional activator of the stress sigma factor σS/RpoS". Biomolecular Concepts 7, № 3 (2016): 197–204. http://dx.doi.org/10.1515/bmc-2016-0006.

Full text

Abstract:

AbstractThe bacterial RNA polymerase (RNAP) holoenzyme is a multisubunit core enzyme associated with a σ factor that is required for promoter-specific transcription initiation. Besides a primary σ responsible for most of the gene expression during active growth, bacteria contain alternative σ factors that control adaptive responses. A recurring strategy in the control of σ factor activity is their sequestration by anti-sigma factors that occlude the RNAP binding determinants, reducing their activity. In contrast, the unconventional transcription factor Crl binds specifically to the alternative

APA, Harvard, Vancouver, ISO, and other styles

10

Ho, Khang, та Rasika M. Harshey. "Membrane-associated σ factors disrupt rRNA operon clustering in Escherichia coli". PLOS Biology 23, № 4 (2025): e3003113. https://doi.org/10.1371/journal.pbio.3003113.

Full text

Abstract:

Chromosomal organization in Escherichia coli as examined by Hi-C methodology indicates that long-range interactions are sparse. Yet, spatial co-localization or “clustering” of 6/7 ribosomal RNA (rrn) operons distributed over half the 4.6 Mbp genome has been captured by two other methodologies—fluorescence microscopy and Mu transposition. Our current understanding of the mechanism of clustering is limited to mapping essential cis elements. To identify trans elements, we resorted to perturbing the system by chemical and physical means and observed that heat shock disrupts clustering. Levels of σ

APA, Harvard, Vancouver, ISO, and other styles

11

Tamizi, Amin-Asyraf, Norliza Abu-Bakar, Aimera-Farhana Samsuddin, Lina Rozano, Rohaiza Ahmad-Redzuan, and Abdul-Munir Abdul-Murad. "Characterisation and Mutagenesis Study of An Alternative Sigma Factor Gene (hrpL) from Erwinia mallotivora Reveal Its Central Role in Papaya Dieback Disease." Biology 9, no. 10 (2020): 323. http://dx.doi.org/10.3390/biology9100323.

Full text

Abstract:

The alternative sigma (σ) factor E, RpoE or HrpL, has been reported to be involved in stress- and pathogenicity-related transcription initiation in Escherichia coli and many other Gram-negative bacteria, including Erwinia spp. and Pseudomonas spp. A previous study identified the hrpL/rpoE transcript as one of the significant differentially expressed genes (DEGs) during early E. mallotivora infection in papaya and those data serve as the basis of the current project. Here, the full coding DNA sequence (CDS) of hrpL from E. mallotivora (EmhrpL) was determined to be 549 bp long, and it encoded a

APA, Harvard, Vancouver, ISO, and other styles

12

Paul, Deborupa, and Sanmitra Ghosh. "An overview of heat-stress response regulation in Gram-negative bacteria considering Escherichia coli as a model organism." Journal of Experimental Biology and Agricultural Sciences 10, no. 1 (2022): 190–200. http://dx.doi.org/10.18006/2022.10(1).190.200.

Full text

Abstract:

Response to heat stress (HSR) is a key stress response for endurance in Escherichia coli mediated by transcriptional factor σ-32. Even though there has been extensive investigation on the contribution of proteins and chaperones in retaining protein stability in cells under stress conditions, limited information is available regarding the dynamic nature of mechanisms regulating the activity of the highly conserved heat shock proteins (Hsps). Several gene expression-based studies suggest the pivotal role of Hsp70 (DnaK) in the regulation of the expression of heat shock genes (Hsg). Direct intera

APA, Harvard, Vancouver, ISO, and other styles

13

Rédly, Gyula Alan, and Keith Poole. "FpvIR Control of fpvA Ferric Pyoverdine Receptor Gene Expression in Pseudomonas aeruginosa: Demonstration of an Interaction between FpvI and FpvR and Identification of Mutations in Each Compromising This Interaction." Journal of Bacteriology 187, no. 16 (2005): 5648–57. http://dx.doi.org/10.1128/jb.187.16.5648-5657.2005.

Full text

Abstract:

ABSTRACT FpvR is a presumed cytoplasmic membrane-associated anti-sigma factor that controls the activities of extracytoplasmic function sigma factors PvdS and FpvI responsible for transcription of pyoverdine biosynthetic genes and the ferric pyoverdine receptor gene, fpvA, respectively. Using deletion analysis and an in vivo bacterial two-hybrid system, FpvR interaction with these σ factors was confirmed and shown to involve the cytoplasmic N-terminal 67 amino acid resides of FpvR. FpvR bound specifically to a C-terminal region of FpvI corresponding to region 4 of the σ70 family of sigma facto

APA, Harvard, Vancouver, ISO, and other styles

14

Delumeau, Olivier, Richard J. Lewis та Michael D. Yudkin. "Protein-Protein Interactions That Regulate the Energy Stress Activation of σB in Bacillus subtilis". Journal of Bacteriology 184, № 20 (2002): 5583–89. http://dx.doi.org/10.1128/jb.184.20.5583-5589.2002.

Full text

Abstract:

ABSTRACT σB is an alternative σ factor that controls the general stress response in Bacillus subtilis. In the absence of stress, σB is negatively regulated by anti-σ factor RsbW. RsbW is also a protein kinase which can phosphorylate RsbV. When cells are stressed, RsbW binds to unphosphorylated RsbV, produced from the phosphorylated form of RsbV by two phosphatases (RsbU and RsbP) which are activated by stress. We now report the values of the Km for ATP and the Ki for ADP of RsbW (0.9 and 0.19 mM, respectively), which reinforce the idea that the kinase activity of RsbW is directly regulated in

APA, Harvard, Vancouver, ISO, and other styles

15

Nambigari, Navaneetha. "Cancer Therapeutics: Structure-Based Drug Design of Inhibitors for a Novel Angiogenic Growth Factor." Mathematical Biology and Bioinformatics 18, no. 1 (2023): 72–88. http://dx.doi.org/10.17537/2023.18.72.

Full text

Abstract:

Angiogenesis, the formation of new blood vessels, is a critical and rate-limiting tumor growth step controlled by pro-angiogenic factors and specific inhibitors. Tumor angiogenesis is essential for cancer progression and metastasis. Platelet growth factors (PDGF) and their receptors (PDGFR) are associated with tumor angiogenesis through overexpression of PDGF. Inhibition of PDGF and its signaling pathway is a new approach to the discovery of anticancer therapeutic agents. The present study focuses on the PDGF-C protein in the identification of novel anti-angiogenic compounds. MODELLER 9.10 sof

APA, Harvard, Vancouver, ISO, and other styles

16

Dehbi, Mohammed, Gregory Moeck, Francis F. Arhin, et al. "Inhibition of Transcription in Staphylococcus aureus by a Primary Sigma Factor-Binding Polypeptide from Phage G1." Journal of Bacteriology 191, no. 12 (2009): 3763–71. http://dx.doi.org/10.1128/jb.00241-09.

Full text

Abstract:

ABSTRACT The primary sigma factor of Staphylococcus aureus, σSA, regulates the transcription of many genes, including several essential genes, in this bacterium via specific recognition of exponential growth phase promoters. In this study, we report the existence of a novel staphylococcal phage G1-derived growth inhibitory polypeptide, referred to as G1ORF67, that interacts with σSA both in vivo and in vitro and regulates its activity. Delineation of the minimal domain of σSA that is required for its interaction with G1ORF67 as amino acids 294 to 360 near the carboxy terminus suggests that the

APA, Harvard, Vancouver, ISO, and other styles

17

Griffiths-Jones, D., Y. Sylvestre Garcia, D. Ryder, et al. "POS0850 A PHASE II RANDOMISED CONTROLLED TRIAL OF ORAL PREDNISOLONE IN EARLY DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS (PRedSS)." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 717.2–718. http://dx.doi.org/10.1136/annrheumdis-2022-eular.694.

Full text

Abstract:

BackgroundA highly controversial question is whether or not corticosteroids should be prescribed for patients with early diffuse cutaneous systemic sclerosis (dcSSc). Although the painful and disabling features of early dcSSc (including tight itchy skin, contractures, fatigue) have an inflammatory basis and are likely to respond to corticosteroids, corticosteroids are a risk factor for potentially life-threatening scleroderma renal crisis.ObjectivesOur aim was to examine safety and efficacy of moderate dose prednisolone in patients with early dcSSc. Specific objectives were to evaluate whether

APA, Harvard, Vancouver, ISO, and other styles

18

McGuffie, Bryan A., Isabelle Vallet-Gely та Simon L. Dove. "σ Factor and Anti-σ Factor That Control Swarming Motility and Biofilm Formation in Pseudomonas aeruginosa". Journal of Bacteriology 198, № 5 (2015): 755–65. http://dx.doi.org/10.1128/jb.00784-15.

Full text

Abstract:

ABSTRACTPseudomonas aeruginosais capable of causing a variety of acute and chronic infections. Here, we provide evidence thatsbrR(PA2895), a gene previously identified as required during chronicP. aeruginosarespiratory infection, encodes an anti-σ factor that inhibits the activity of its cognate extracytoplasmic-function σ factor, SbrI (PA2896). Bacterial two-hybrid analysis identified an N-terminal region of SbrR that interacts directly with SbrI and that was sufficient for inhibition of SbrI-dependent gene expression. We show that SbrI associates with RNA polymerasein vivoand identify the Sb

APA, Harvard, Vancouver, ISO, and other styles

19

Campbell, Elizabeth A., Shoko Masuda, Jing L. Sun та ін. "Crystal Structure of the Bacillus stearothermophilus Anti-σ Factor SpoIIAB with the Sporulation σ Factor σF". Cell 108, № 6 (2002): 795–807. http://dx.doi.org/10.1016/s0092-8674(02)00662-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Maillard, Antoine P., Eric Girard, Widade Ziani, Isabelle Petit-Härtlein, Richard Kahn та Jacques Covès. "The Crystal Structure of the Anti-σ Factor CnrY in Complex with the σ Factor CnrH Shows a New Structural Class of Anti-σ Factors Targeting Extracytoplasmic Function σ Factors". Journal of Molecular Biology 426, № 12 (2014): 2313–27. http://dx.doi.org/10.1016/j.jmb.2014.04.003.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Lachowicz, Mirosław, Henryk Leszczyński, and Elżbieta Puźniakowska–Gałuch. "Diffusive and Anti-Diffusive Behavior for Kinetic Models of Opinion Dynamics." Symmetry 11, no. 8 (2019): 1024. http://dx.doi.org/10.3390/sym11081024.

Full text

Abstract:

In the present paper, we study a class of nonlinear integro-differential equations of a kinetic type describing the dynamics of opinion for two types of societies: conformist ( σ = 1 ) and anti-conformist ( σ = - 1 ). The essential role is played by the symmetric nature of interactions. The class may be related to the mesoscopic scale of description. This means that we are going to statistically describe an individual state of an agent of the system. We show that the corresponding equations result at the macroscopic scale in two different pictures: anti-diffusive ( σ = 1 ) and diffusive ( σ =

APA, Harvard, Vancouver, ISO, and other styles

22

Werstiuk, Nick Henry, та Jiangong Ma. "An AM1 calculational study of the Diels–Alder addition of maleic anhydride to C5-substituted pentamethylcyclopentadienes and 2,5-dimethylthiophene oxide. An attempt to ascertain the factors controlling the π-facial selectivities and relative reactivities". Canadian Journal of Chemistry 72, № 12 (1994): 2493–505. http://dx.doi.org/10.1139/v94-316.

Full text

Abstract:

The Diels–Alder reactions of maleic anhydride (1) with a group of C5-substituted cyclopentadienes and 2,5-dimethylthiophene oxide (5) have been studied with the semi-empirical method AM1. We find that the facial selectivities and relative reactivities found experimentally for six dienes (2a–2f) are accurately reproduced at this level of theory. The results of the calculational study provide no concrete support for the proposal that σ–σ* hyperconjugation in the transition state – an interaction between a σ bond at C5 of the cyclopentadiene and the incipient σ bonds anti to it (the Cieplak effec

APA, Harvard, Vancouver, ISO, and other styles

23

Yamato, Takehiko, Hideo Kamimura, and Hirohisa Tsuzuki. "ipso-Nitration of tert-butyl[n.2]metacyclophanes; through-space electronic interactions between two benzene rings." Canadian Journal of Chemistry 76, no. 7 (1998): 997–1005. http://dx.doi.org/10.1139/v98-111.

Full text

Abstract:

The selective introduction of one or two nitro groups by direct replacement of tert-butyl groups via the ipso aromatic nitration of the meta-bridged aromatic compounds having two arene rings is described. The ipso-nitration at the tert-butyl groups of syn- and anti-di-tert-butyl-dimethoxy[n.2]metacyclophanes 1 is attributed to the highly activated character of the aryl ring and the increased stabilization of a σ-complex intermediate arising from the dienone-type σ-complex intermediate possible in the case of an internally methoxy substituent. However, only one tert-butyl group is ipso-nitrated

APA, Harvard, Vancouver, ISO, and other styles

24

Paudel, Hari Ram, Lucas José Karas та Judy I.-Chia Wu. "On the reciprocal relationship between σ-hole bonding and (anti)aromaticity gain in ketocyclopolyenes". Organic & Biomolecular Chemistry 18, № 27 (2020): 5125–29. http://dx.doi.org/10.1039/d0ob01076f.

Full text

Abstract:

σ-Hole bonding interactions (e.g., tetrel, pnictogen, chalcogen, and halogen bonding) can polarize π-electrons to enhance cyclic [4n] π-electron delocalization (i.e., antiaromaticity gain) or cyclic [4n + 2] π-electron delocalization (i.e., aromaticity gain).

APA, Harvard, Vancouver, ISO, and other styles

25

Sorenson, Margareta K., Soumya S. Ray та Seth A. Darst. "Crystal Structure of the Flagellar σ/Anti-σ Complex σ28/FlgM Reveals an Intact σ Factor in an Inactive Conformation". Molecular Cell 14, № 1 (2004): 127–38. http://dx.doi.org/10.1016/s1097-2765(04)00150-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Hubin, Elizabeth A., Aline Tabib-Salazar, Laurence J. Humphrey, et al. "Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA." Proceedings of the National Academy of Sciences 112, no. 23 (2015): 7171–76. http://dx.doi.org/10.1073/pnas.1504942112.

Full text

Abstract:

Gene expression is highly regulated at the step of transcription initiation, and transcription activators play a critical role in this process. RbpA, an actinobacterial transcription activator that is essential inMycobacterium tuberculosis(Mtb), binds selectively to group 1 and certain group 2 σ-factors. To delineate the molecular mechanism of RbpA, we show that theMtbRbpA σ-interacting domain (SID) and basic linker are sufficient for transcription activation. We also present the crystal structure of theMtbRbpA-SID in complex with domain 2 of the housekeeping σ-factor, σA. The structure explai

APA, Harvard, Vancouver, ISO, and other styles

27

Campbell, Elizabeth A., та Seth A. Darst. "The anti-σ factor SpoIIAB forms a 2:1 complex with σF, contacting multiple conserved regions of the σ factor". Journal of Molecular Biology 300, № 1 (2000): 17–28. http://dx.doi.org/10.1006/jmbi.2000.3838.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Masuda, Shoko, Katsuhiko S. Murakami, Sheng Wang та ін. "Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-σ Factor SpoIIAB in Complex with the Anti-anti-σ SpoIIAA". Journal of Molecular Biology 340, № 5 (2004): 941–56. http://dx.doi.org/10.1016/j.jmb.2004.05.040.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Ledermann, Raphael, Ilka Bartsch, Barbara Müller, Janine Wülser, and Hans-Martin Fischer. "A Functional General Stress Response of Bradyrhizobium diazoefficiens Is Required for Early Stages of Host Plant Infection." Molecular Plant-Microbe Interactions® 31, no. 5 (2018): 537–47. http://dx.doi.org/10.1094/mpmi-11-17-0284-r.

Full text

Abstract:

Phylogenetically diverse bacteria respond to various stress conditions by mounting a general stress response (GSR) resulting in the induction of protection or damage repair functions. In α-proteobacteria, the GSR is induced by a regulatory cascade consisting of the extracytoplasmic function (ECF) σ factor σEcfG, its anti-σ factor NepR, and the anti-anti-σ factor PhyR. We have reported previously that σEcfG and PhyR of Bradyrhizobium diazoefficiens (formerly named Bradyrhizobium japonicum), the nitrogen-fixing root nodule symbiont of soybean and related legumes, are required for efficient symbi

APA, Harvard, Vancouver, ISO, and other styles

30

Weinhold, Frank. "Anti-Electrostatic Pi-Hole Bonding: How Covalency Conquers Coulombics." Molecules 27, no. 2 (2022): 377. http://dx.doi.org/10.3390/molecules27020377.

Full text

Abstract:

Intermolecular bonding attraction at π-bonded centers is often described as “electrostatically driven” and given quasi-classical rationalization in terms of a “pi hole” depletion region in the electrostatic potential. However, we demonstrate here that such bonding attraction also occurs between closed-shell ions of like charge, thereby yielding locally stable complexes that sharply violate classical electrostatic expectations. Standard DFT and MP2 computational methods are employed to investigate complexation of simple pi-bonded diatomic anions (BO−, CN−) with simple atomic anions (H−, F−) or

APA, Harvard, Vancouver, ISO, and other styles

31

Kodgire, Prashant, and K. Krishnamurthy Rao. "hag expression in Bacillus subtilis is both negatively and positively regulated by ScoC." Microbiology 155, no. 1 (2009): 142–49. http://dx.doi.org/10.1099/mic.0.021899-0.

Full text

Abstract:

In Bacillus subtilis, motility and chemotaxis require the expression of hag, which encodes flagellin. This gene is transcribed by the σ D form of RNA polymerase and is regulated by a group of proteins called transition state regulators (TSRs). Our studies show that hag transcription is negatively regulated by the transition state regulator ScoC, by binding to its promoter. Furthermore, ScoC, indirectly, also positively regulates hag by increasing the availability of σ D by downregulating the levels of the anti-σ D-factor FlgM. We further show that the positive regulation by ScoC predominates o

APA, Harvard, Vancouver, ISO, and other styles

32

Guzina, Jelena, та Marko Djordjevic. "Promoter Recognition by Extracytoplasmic Function σ Factors: Analyzing DNA and Protein Interaction Motifs". Journal of Bacteriology 198, № 14 (2016): 1927–38. http://dx.doi.org/10.1128/jb.00244-16.

Full text

Abstract:

ABSTRACTExtracytoplasmicfunction (ECF) σ factors are the largest and the most diverse group of alternative σ factors, but their mechanisms of transcription are poorly studied. This subfamily is considered to exhibit a rigid promoter structure and an absence of mixing and matching; both −35 and −10 elements are considered necessary for initiating transcription. This paradigm, however, is based on very limited data, which bias the analysis of diverse ECF σ subgroups. Here we investigate DNA and protein recognition motifs involved in ECF σ factor transcription by a computational analysis of canon

APA, Harvard, Vancouver, ISO, and other styles

33

Ho, Theresa D., та Craig D. Ellermeier. "PrsW Is Required for Colonization, Resistance to Antimicrobial Peptides, and Expression of Extracytoplasmic Function σ Factors in Clostridium difficile". Infection and Immunity 79, № 8 (2011): 3229–38. http://dx.doi.org/10.1128/iai.00019-11.

Full text

Abstract:

ABSTRACTClostridium difficileis an anaerobic, Gram-positive, spore-forming, opportunistic pathogen that is the most common cause of hospital-acquired infectious diarrhea. In numerous pathogens, stress response mechanisms are required for survival within the host. Extracytoplasmic function (ECF) σ factors are a major family of signal transduction systems, which sense and respond to extracellular stresses. We have identified threeC. difficileECF σ factors. These ECF σ factors, CsfT, CsfU, and CsfV, induce their own expressions and are negatively regulated by their cognate anti-σ factors, RsiT, R

APA, Harvard, Vancouver, ISO, and other styles

34

Kallifidas, Dimitris, Derek Thomas, Phillip Doughty та Mark S. B. Paget. "The σ R regulon of Streptomyces coelicolor A3(2) reveals a key role in protein quality control during disulphide stress". Microbiology 156, № 6 (2010): 1661–72. http://dx.doi.org/10.1099/mic.0.037804-0.

Full text

Abstract:

Diamide is an artificial disulphide-generating electrophile that mimics an oxidative shift in the cellular thiol–disulphide redox state (disulphide stress). The Gram-positive bacterium Streptomyces coelicolor senses and responds to disulphide stress through the σ R–RsrA system, which comprises an extracytoplasmic function (ECF) sigma factor and a redox-active anti-sigma factor. Known targets that aid in the protection and recovery from disulphide stress include the thioredoxin system and genes involved in producing the major thiol buffer mycothiol. Here we determine the global response to diam

APA, Harvard, Vancouver, ISO, and other styles

35

ROBERTS, H. L. L., L. CHANG, and C. D. ROBERTS. "IMPACT OF DYNAMICAL CHIRAL SYMMETRY BREAKING ON MESON STRUCTURE AND INTERACTIONS." International Journal of Modern Physics A 26, no. 03n04 (2011): 371–77. http://dx.doi.org/10.1142/s0217751x11051688.

Full text

Abstract:

We provide a glimpse of recent progress in meson physics made via QCD's Dyson-Schwinger equations with: a perspective on confinement and dynamical chiral symmetry breaking (DCSB); a précis on the physics of in-hadron condensates; results for the masses of the π, σ, ρ, a1 mesons and their first-radial excitations; and an illustration of the impact of DCSB on the pion form factor.

APA, Harvard, Vancouver, ISO, and other styles

36

Meng, Ying, and Qiman Liu. "New Insights into Adsorption Properties of the Tubular Au26 from AIMD Simulations and Electronic Interactions." Molecules 28, no. 7 (2023): 2916. http://dx.doi.org/10.3390/molecules28072916.

Full text

Abstract:

Recently, we revealed the electronic nature of the tubular Au26 based on spherical aromaticity. The peculiar structure of the Au26 could be an ideal catalyst model for studying the adsorptions of the Au nanotubes. However, through Google Scholar, we found that no one has reported connections between the structure and reactivity properties of Au26. Here, three kinds of molecules are selected to study the fundamental adsorption behaviors that occur on the surface of Au26. When one CO molecule is adsorbed on the Au26, the σ-hole adsorption structure is quickly identified as belonging to a ground

APA, Harvard, Vancouver, ISO, and other styles

37

Stockwell, S. B., L. Reutimann, and M. L. Guerinot. "A Role for Bradyrhizobium japonicum ECF16 Sigma Factor EcfS in the Formation of a Functional Symbiosis with Soybean." Molecular Plant-Microbe Interactions® 25, no. 1 (2012): 119–28. http://dx.doi.org/10.1094/mpmi-07-11-0188.

Full text

Abstract:

Alternative sigma (σ) factors, proteins that recruit RNA polymerase core enzyme to target promoters, are one mechanism by which bacteria transcriptionally regulate groups of genes in response to environmental stimuli. A class of σ70 proteins, termed extracytoplasmic function (ECF) σ factors, are involved in cellular processes such as bacterial stress responses and virulence. Here, we describe an ECF16 σ factor, EcfS (Blr4928) from the gram-negative soil bacterium Bradyrhizobium japonicum USDA110, that plays a critical role in the establishment of a functional symbiosis with soybean. Nonpolar i

APA, Harvard, Vancouver, ISO, and other styles

38

Hastie, Jessica L., Kyle B. Williams, Carolina Sepúlveda, Jon C. Houtman, Katrina T. Forest та Craig D. Ellermeier. "Evidence of a Bacterial Receptor for Lysozyme: Binding of Lysozyme to the Anti-σ Factor RsiV Controls Activation of the ECF σ Factor σV". PLoS Genetics 10, № 10 (2014): e1004643. http://dx.doi.org/10.1371/journal.pgen.1004643.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Beaucher, Jocelyn, Sébastien Rodrigue, Pierre-Étienne Jacques, Issar Smith, Ryszard Brzezinski та Luc Gaudreau. "Novel Mycobacterium tuberculosis anti-σ factor antagonists control σF activity by distinct mechanisms". Molecular Microbiology 45, № 6 (2002): 1527–40. http://dx.doi.org/10.1046/j.1365-2958.2002.03135.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Luebke, Justin L., Daniel S. Eaton, Joseph R. Sachleben та Sean Crosson. "Allosteric control of a bacterial stress response system by an anti-σ factor". Molecular Microbiology 107, № 2 (2017): 164–79. http://dx.doi.org/10.1111/mmi.13868.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Aldridge, Phillip, Joyce E. Karlinsey, Eric Becker, Fabienne F. V. Chevance та Kelly T. Hughes. "Flk prevents premature secretion of the anti-σ factor FlgM into the periplasm". Molecular Microbiology 61, № 1 (2006): 269. http://dx.doi.org/10.1111/j.1365-2958.2006.05201.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Wecke, Tina, Birgit Veith, Armin Ehrenreich, and Thorsten Mascher. "Cell Envelope Stress Response in Bacillus licheniformis: Integrating Comparative Genomics, Transcriptional Profiling, and Regulon Mining To Decipher a Complex Regulatory Network." Journal of Bacteriology 188, no. 21 (2006): 7500–7511. http://dx.doi.org/10.1128/jb.01110-06.

Full text

Abstract:

ABSTRACT The envelope is an essential structure of the bacterial cell, and maintaining its integrity is a prerequisite for survival. To ensure proper function, transmembrane signal-transducing systems, such as two-component systems (TCS) and extracytoplasmic function (ECF) σ factors, closely monitor its condition and respond to harmful perturbations. Both systems consist of a transmembrane sensor protein (histidine kinase or anti-σ factor, respectively) and a corresponding cytoplasmic transcriptional regulator (response regulator or σ factor, respectively) that mediates the cellular response t

APA, Harvard, Vancouver, ISO, and other styles

43

Zavodovsky, B. V., Yu R. Akhverdyan, E. V. Papichev, Yu V. Polyakova, and L. E. Sivordova. "Relationship between the level of antibodies to the RA-33 antigen and the course of rheumatoid arthritis." YAKUT MEDICAL JOURNAL 88, no. 4 (2024): 9–12. https://doi.org/10.25789/ymj.2024.88.02.

Full text

Abstract:

Objective: to study the relationship between the serum level of antibodies to the RA-33 antigen and the characteristics of the course of rheumatoid arthritis (RA). Materials and methods. The study included 88 patients with a diagnosis of RA that met the ACR/EULAR criteria, 2010. All observed study participants were women (n=100%), aged from 22 to 81 years (M ± σ, 54.3 ± 12.1 years). Rheumatoid factor was detected in 64 people (72.7%). 59 (67%) study participants were positive for anti-CCP. The duration of RA was 0.5–30 years (M ± σ, 11.2 ± 8.6 years), the degree of activity according to DAS28:

APA, Harvard, Vancouver, ISO, and other styles

44

Fang, Chengli, Lingting Li, Liqiang Shen, et al. "Structures and mechanism of transcription initiation by bacterial ECF factors." Nucleic Acids Research 47, no. 13 (2019): 7094–104. http://dx.doi.org/10.1093/nar/gkz470.

Full text

Abstract:

Abstract Bacterial RNA polymerase (RNAP) forms distinct holoenzymes with extra-cytoplasmic function (ECF) σ factors to initiate specific gene expression programs. In this study, we report a cryo-EM structure at 4.0 Å of Escherichia coli transcription initiation complex comprising σE—the most-studied bacterial ECF σ factor (Ec σE-RPo), and a crystal structure at 3.1 Å of Mycobacterium tuberculosis transcription initiation complex with a chimeric σH/E (Mtb σH/E-RPo). The structure of Ec σE-RPo reveals key interactions essential for assembly of E. coli σE-RNAP holoenzyme and for promoter recognit

APA, Harvard, Vancouver, ISO, and other styles

45

Kim, Yunok, Jaeseung Yoo, Donghyuk Jang, et al. "Further utilization of a Mn redox reaction via control of structural disorder in olivine systems." Journal of Materials Chemistry A 6, no. 28 (2018): 13743–50. http://dx.doi.org/10.1039/c8ta03631d.

Full text

Abstract:

Anti-site defects are a critical factor for improving the electrochemical performance of olivines, and these defects can be decreased by introducing non-stoichiometry in the crystal structure that enables selective further oxidation of Mn in LiFe<sub>0.5−x</sub>Mn<sub>0.5−x</sub>PO<sub>4−σ</sub> type olivine systems.

APA, Harvard, Vancouver, ISO, and other styles

46

Alhadlaq, Meshari Ahmed, Jeffrey Green, and Bassam K. Kudhair. "Analysis of Kytococcus sedentarius Strain Isolated from a Dehumidifier Operating in a University Lecture Theatre: Systems for Aerobic Respiration, Resisting Osmotic Stress, and Sensing Nitric Oxide." Microbial Physiology 31, no. 2 (2021): 135–45. http://dx.doi.org/10.1159/000512751.

Full text

Abstract:

A strain of <i>Kytococcus sedentarius</i> was isolated from a dehumidifier operating in a university lecture theatre. Genome analysis and phenotypic characterisation showed that this strain, <i>K. sedentarius</i> MBB13, was a moderately halotolerant aerobe with a branched aerobic electron transport chain and genes that could contribute to erythromycin resistance. The major compatible solute was glycine betaine, with ectoine and proline being deployed at higher osmolarities. Actinobacteria possess multiple WhiB-like (Wbl) regulatory proteins, and <i>K. sedentarius&

APA, Harvard, Vancouver, ISO, and other styles

47

Banerjee, Rajdeep, Paulami Rudra, Abinit Saha, and Jayanta Mukhopadhyay. "Recombinant Reporter Assay Using Transcriptional Machinery of Mycobacterium tuberculosis." Journal of Bacteriology 197, no. 3 (2014): 646–53. http://dx.doi.org/10.1128/jb.02445-14.

Full text

Abstract:

Development of anin vivogene reporter assay to assess interactions among the components of the transcription machinery inMycobacterium tuberculosisremains a challenge to scientists due to the tediousness of generation of mutant strains of the extremely slow-growing bacterium. We have developed a recombinant mCherry reporter assay that enables us to monitor the interactions ofMycobacterium tuberculosistranscriptional regulators with its promotersin vivoinEscherichia coli. The assay involves a three-plasmid expression system inE. coliwherein two plasmids are responsible forM. tuberculosisRNA pol

APA, Harvard, Vancouver, ISO, and other styles

48

VIOLA, MARIA GRAZIA. "ON A SUBFACTOR CONSTRUCTION OF A FACTOR NON-ANTIISOMORPHIC TO ITSELF." International Journal of Mathematics 15, no. 08 (2004): 833–54. http://dx.doi.org/10.1142/s0129167x04002570.

Full text

Abstract:

We define a ℤ3-kernel α on [Formula: see text] and a ℤ3-kernel β on the hyperfinite II 1 factor R, which have conjugate obstruction to lifting. Hence, α⊗β can be perturbed by an inner automorphism to produce an action γ on [Formula: see text]. The aim of this paper is to show that the factor [Formula: see text], which is similar to Connes's example of a II 1 factor non-antiisomorphic to itself, is the enveloping algebra of an inclusion of II 1 factors A⊂B. Here A is an interpolated free group factor and B is isomorphic to the crossed product A⋊θℤ9, where θ is a ℤ3-kernel of A with non-trivial

APA, Harvard, Vancouver, ISO, and other styles

49

Torres-Gómez, Héctor, Constantin Daniliuc, Dirk Schepmann, Erik Laurini, Sabrina Pricl та Bernhard Wünsch. "Propellanes as Rigid Scaffolds for the Stereodefined Attachment of σ-Pharmacophoric Structural Elements to Achieve σ Affinity". International Journal of Molecular Sciences 22, № 11 (2021): 5685. http://dx.doi.org/10.3390/ijms22115685.

Full text

Abstract:

Following the concept of conformationally restriction of ligands to achieve high receptor affinity, we exploited the propellane system as rigid scaffold allowing the stereodefined attachment of various substituents. Three types of ligands were designed, synthesized and pharmacologically evaluated as σ1 receptor ligands. Propellanes with (1) a 2-methoxy-5-methylphenylcarbamate group at the “left” five-membered ring and various amino groups on the “right” side; (2) benzylamino or analogous amino moieties on the “right” side and various substituents at the left five-membered ring and (3) various

APA, Harvard, Vancouver, ISO, and other styles

50

Harbottle, John, and Nikolay Zenkin. "Ureidothiophene inhibits interaction of bacterial RNA polymerase with –10 promotor element." Nucleic Acids Research 48, no. 14 (2020): 7914–23. http://dx.doi.org/10.1093/nar/gkaa591.

Full text

Abstract:

Abstract Bacterial RNA polymerase is a potent target for antibiotics, which utilize a plethora of different modes of action, some of which are still not fully understood. Ureidothiophene (Urd) was found in a screen of a library of chemical compounds for ability to inhibit bacterial transcription. The mechanism of Urd action is not known. Here, we show that Urd inhibits transcription at the early stage of closed complex formation by blocking interaction of RNA polymerase with the promoter –10 element, while not affecting interactions with –35 element or steps of transcription after promoter clo

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!