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Journal articles on the topic 'Anti-corona system'

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1

Cheng, Yujia, and Guang Yu. "Parametric Study and Improvement of Anti-Corona Structure in Stator Bar End Based on Finite Element Analysis." Coatings 15, no. 4 (2025): 484. https://doi.org/10.3390/coatings15040484.

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Voltage withstand tests on stator bars can cause destructive phenomena such as thermal breakdown and flashover discharge on the surface of the anti-corona layer. This study optimizes the anti-corona structure at a stator bar’s end to prevent such failures using a 120 MW water-cooled turbogenerator with a rated voltage of 15.75 kV. For a well-designed anti-corona system, the maximum potential gradient of the stator bar should be lower than the discharge intensity of air corona. In our design, the electric field intensity is maintained below 3.1 kV/cm, and the maximum surface loss in the anti-co
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2

Radha, S., S. P. Rajalakshmi, K. Subash, and K. Samraj. "A Perspective Review on <i>Siddha</i> System of Medicine in the Management of Corona Virus Disease 2019." Journal of Natural Remedies 21, no. 2 (2021): 109. http://dx.doi.org/10.18311/jnr/2021/25876.

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Respiratory Tract Infections (RTIs) are the most common, and potentially most severe, of infections treated by health care practitioners. Lower RTIs along with influenza, are the most common cause of death by infection. The fatality risk is doubled if the person is with other morbid conditions or in extremes of age. These seasonal respiratory infections caused by viruses are of more concern as their spread is very vast than we imagine. COVID-19 (corona virus disease 2019) is such a pandemic respiratory illness caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), a strain of
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3

Sasi Priya T. "Impact of siddha kaya karpam: A preventive intervention for COVID-19: A review." World Journal of Biology Pharmacy and Health Sciences 12, no. 2 (2022): 176–84. http://dx.doi.org/10.30574/wjbphs.2022.12.2.0203.

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The Siddha system of medicine is not only well known for its curative measures but also this system spreads its wings over preventive measures too. COVID-19 is the contagious disease caused by the recently identified and named as Novel corona virus (SARS CoV-2). Its spread is considered to be the current pandemic. In this situation prevention is considered to be wiser than treatment. In Siddha system of medicine, a wide range of immune boosting formulations are available. In which Siddha Kaya karpam is also one among the treatment modality to increase one’s immunity. Inji, Chukku (Zingiber off
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4

Drohovoz, S. M., A. L. Shtroblia, V. V. Shtroblia, et al. "THERAPEUTIC POTENTIAL OF CARBOXYTHERAPY AND ITS IMPACT ON THE PATHOGENESIS AND SYMPTOMS OF COVID-19." Likarska sprava, no. 1-2 (March 30, 2022): 5–13. http://dx.doi.org/10.31640/2706-8803-2022-(1-2)-01.

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Corona virus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus and its mutants. COVID-19 is often the cause of the development of pathologies on the part of the respiratory system against the background of hypoxia. One of the alternative methods of eliminating hypoxia is carboxytherapy, since carbon dioxide (CO2) has an anti-hypoxic, antioxidant effect due to its physiological properties. The use of CO2 in the treatment can be effective in eliminating the symptoms of pleuropulmonary pathology, as CO2 has anti-inflammatory, antiviral and antimicrobial effects.
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5

Andreev, A.M., I.A. Andreev, V.O. Belko, A.S. Reznik, A.N. Smirnov, and A.A. Stepanov. "Modelling of Electrical Discharge Processes for Optimization of CoronaProtection System of High Voltage Rotating Machines Insulation." Problemele Energeticii Regionale 2(46) (March 15, 2020): 33–42. https://doi.org/10.5281/zenodo.3898227.

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The aim of this work is to study the influence of technological defects in stator windings electrical insulation system on the inception of partial discharges in the stator slot of air-cooled electric rotating machines. By means of Comsol Multiphysics finite-element modeling software the electrophysical processes in high-voltage stator insulation with corona-protection coatings are numerically studied for both Resin-Rich (RR) and vacuum pressure impregnation (VPI) technologies. The most important results are the conclusions made about the possibility of slot partial discharges in the insulatio
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6

Sasi, Priya T. "Impact of siddha kaya karpam: A preventive intervention for COVID-19: A review." World Journal of Biology Pharmacy and Health Sciences 12, no. 2 (2022): 176–84. https://doi.org/10.5281/zenodo.7607179.

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The Siddha system of medicine is not only well known for its curative measures but also this system spreads its wings over preventive measures too. COVID-19 is the contagious disease caused by the recently identified and named as Novel corona virus (SARS CoV-2). Its spread is considered to be the current pandemic. In this situation prevention is considered to be wiser than treatment. In Siddha system of medicine, a wide range of immune boosting formulations are available. In which Siddha Kaya karpam is also one among the treatment modality to increase one&rsquo;s immunity. Inji, Chukku (<em>Zi
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7

Husdi, Husdi. "APLIKASI GLOBAL POSITIONING SYSTEM (GPS) UNTUK PENCEGAHAN PENYEBARAN WABAH PENYAKIT." Simtek : jurnal sistem informasi dan teknik komputer 6, no. 2 (2021): 167–72. http://dx.doi.org/10.51876/simtek.v6i2.111.

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Dunia Saat ini tengah dilanda kekhawatiran dengan mewabahnya virus corona yang bermula dari Wuhan, Sudah banyak korban tewas dan dirawat secara intensif. Para peneliti dari berbagai bidang bahu membahu dan bekerja sama Untuk menanggulangi penyebaran wabah tersebut pada. Seperti halnya pada bidang medis yang berupaya untuk menciptakan vaksin atau anti virus wabah tersebut. Dengan kemajuan teknologi informasi dan komunikasi dapat dimanfaatkan dalam menanggulangi penyebaran wabah berbahaya. Indonesia dengan pengguna media sosial dan internet terbesar perlu membangun sistem pencegahan dini wabah p
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8

Rensmann, Lars, and Thijs de Zee. "The Pandemic Factor." German Politics and Society 40, no. 4 (2022): 69–103. http://dx.doi.org/10.3167/gps.2022.400404.

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Abstract This article examines how and why the covid-19 pandemic featured as a central issue in the Alternative for Germany's 2021 Bundestag election campaign. Using a wide range of political communication tools, the radical right party's opposition to public health policies against the pandemic ranged from a critique of hygienic measures to hosting coronavirus denialism and conspiracy myths suggesting that “the elite” had manufactured “corona hysteria” to subjugate the German people. Mirroring its general radicalization process toward an anti-system movement party, the AfD's campaign primaril
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9

Chauhan, Kavita, Amulya Gupta, and Shruti Agrawal. "Role of Botanical Herbs Used in Covid-19 Treatment and Cure." Plantae Scientia 4, no. 6 (2021): 291–98. http://dx.doi.org/10.32439/ps.v4i6.291-298.

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Corona 2019 (COVID-19) is a new infectious disease caused by acute respiratory syndrome corona virus 2 (SARS-CoV-2) which belongs to the family of corona viruses. The first case appeared in December 2019, and the disease has transformed into a pandemic. Physical disability control is one of the main parts that play a role in its disease and leads to adverse effects for COVID-19 patients. At present, people believe taking herbal treatment that can stop COVID-19. Medicinal plants can distribute as the therapeutic agents so it can help people to fight against the COVID-19 disease by boost their i
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10

Basheer, Maamoun, Elias Saad, Orly Laskar, et al. "Clearance of the SARS-CoV-2 Virus in an Immunocompromised Patient Mediated by Convalescent Plasma without B-Cell Recovery." International Journal of Molecular Sciences 22, no. 16 (2021): 8902. http://dx.doi.org/10.3390/ijms22168902.

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Coronavirus disease (COVID-19) is a contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This case report presents a patient who had difficulty eradicating the corona virus due to being treated with Rituximab, which depletes B lymphocyte cells and therefore disables the production of neutralizing antibodies. The combined use of external anti-viral agents like convalescent plasma, IVIG and Remdesivir successfully helped the patient’s immune system to eradicate the virus without B-cell population recovery. In vitro studies showed that convalescent plasma
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11

Zhitnitsky, Ariel. "Axion quark nuggets. Dark matter and matter–antimatter asymmetry: Theory, observations and future experiments." Modern Physics Letters A 36, no. 18 (2021): 2130017. http://dx.doi.org/10.1142/s0217732321300172.

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We review a testable, the axion quark nugget (AQN) model outside of the standard WIMP paradigm. The model was originally invented to explain the observed similarity between the dark and the visible components, [Formula: see text], in a natural way as both types of matter are formed during the same QCD transition and proportional to the same dimensional fundamental parameter of the system, [Formula: see text]. In this framework, the baryogenesis is actually a charge segregation (rather than charge generation) process which is operational due to the [Formula: see text]-odd axion field, while the
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12

Sen, Binay. "Potentiality and possibility of Medicinal Plants on Ayurvedic Principle in prevention and treatment of COVID-19." Journal of Ayurvedic and Herbal Medicine 6, no. 2 (2020): 100–107. http://dx.doi.org/10.31254/jahm.2020.6216.

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The novel coronavirus disease 2019 (COVID-19) is a pandemic health emergency, caused by the severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. Older people and those with underlying some medical problems are more likely to develop serious illness. Considering different classical and contemporary viewpoints, the newly identified COVID-19 can be categorized under agantuja vyadhi (exogenous disease) by inception, caused by bhoota (organisms
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13

Geetha, A., Bharatha Jothi P, Sushil Kumar PN, and G. Kiruthiga. "Kabhasura Kudineer and its ingredients against COVID -19." Journal of Phytopharmacology 12, no. 4 (2023): 258–64. http://dx.doi.org/10.31254/phyto.2023.12408.

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Siddha System of Medicine is one of the folklore medicines practised by people in South India since several years about 12000 yrs back. Ancient people were aware of knowledge in herbs and its uses. They were also handled several such pandemic conditions on that period itself by Notification, Isolation and used some concoction one such medicine is Kabhasura Kudineer (KSK). It is the Siddha formulation contain 15 ingredients mainly prescribed by Siddha Physicians against Viral Diseases like COVID-19 etc., Covid 19 disease is caused by the virus SARS-COVID virus which is come under CORONA Virus.
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14

Mashin, Dmitrii Vasilyevich. "Anti-crisis management of large public catering chains." Mezhdunarodnaja jekonomika (The World Economics), no. 1 (January 1, 2021): 27–45. http://dx.doi.org/10.33920/vne-04-2101-03.

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Against the background of the conducted research, it was found out that the theoretical base in the fi eld of crisis management is not suffi ciently developed to understand the modern practice of managing large public catering networks in a crisis. In our opinion, this aspect may be the cause of errors on the part of managers managing large catering chains and the likelihood of elimination from the market. Not only since the coronavirus pandemic, authorities and auditors have been demanding that catering establishments have a crisis concept. In the event of a crisis, the company can quickly re
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15

Pratik Sunil Kapse, Samiksha Nandkishor Dhote, Mahesh Bhanudas Narkhede, Pavan Prabhakar Chinchole, Pragati Ramesh Deoche, and Swapnil Datta Gawande. "A review on the 2-Deoxy-D-Glucose (2-DG) in COVID-19 disease." GSC Biological and Pharmaceutical Sciences 19, no. 3 (2022): 008–14. http://dx.doi.org/10.30574/gscbps.2022.19.3.0218.

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This has given a lead to study the role of 2-deoxy-D-glucose (2DG) against COVID-19 (corona virus) disease. We hereby would like to briefly discuss the concept and rationale behind the use of 2DG COVID-19. Virus infections can cause cell damage in many ways. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a cause of the current COVID-19 pandemic, has been extensively studied so far to investigate its pathophysiology and evaluate its impact on the metabolic system of human cells. The Drug Controller General of India (DCGI) has given emergency use approval to 2-deoxy-D-glucose (2-D
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16

Pratik, Sunil Kapse, Nandkishor Dhote Samiksha, Bhanudas Narkhede Mahesh, Prabhakar Chinchole Pavan, Ramesh Deoche Pragati, and Datta Gawande Swapnil. "A review on the 2-Deoxy-D-Glucose (2-DG) in COVID-19 disease." GSC Biological and Pharmaceutical Sciences 19, no. 3 (2022): 008–14. https://doi.org/10.5281/zenodo.6817665.

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This has given a lead to study the role of 2-deoxy-D-glucose (2DG) against COVID-19 (corona virus) disease. We hereby would like to briefly discuss the concept and rationale behind the use of 2DG COVID-19. Virus infections can cause cell damage in many ways. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a cause of the current COVID-19 pandemic, has been extensively studied so far to investigate its pathophysiology and evaluate its impact on the metabolic system of human cells.&nbsp;The Drug Controller General of India (DCGI) has given emergency use approval to 2-deoxy-D-glucose
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17

Subhan Haider, Awais Ahmed Uttra, Saniya Sohail, Ayesha Ghani, and Furqan Ahmed. "EFFECT OF COVID-19 ON GASTROINTESTINAL TRACT AND LIVER, MANIFESTATIONS, PROGNOSIS, MECHANISMS, TREATMENT, AND CHALLENGES: A COMPREHENSIVE REVIEW." International Journal of Pharmacy & Integrated Health Sciences 4, no. 2 (2023): 2–15. http://dx.doi.org/10.56536/ijpihs.v4i2.84.

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Background: The first case of coronavirus was found in December 2019 in Wuhan a city in China since then it has severe impact all over the world. The typical signs and symptoms of coronavirus patients consist of cough, fever, lethargy, and shortness of breath (SOB). Objectives: The current review contains summarized and complete information on the effect of coronavirus on GIT, Liver and its manifestations, prognosis, mechanisms, treatment, and challenges. Methodology: The data was collected via an electronic search of numerous scientific sources including Google scholar, PubMed, and Science Di
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18

Jeong, Ji Hoon, Sun Hwa Kim, Sung Wan Kim, and Tae Gwan Park. "Intracellular Delivery of Poly(ethylene glycol) Conjugated Antisense Oligonucleotide Using Cationic Lipids by Formation of Self-Assembled Polyelectrolyte Complex Micelles." Journal of Nanoscience and Nanotechnology 6, no. 9 (2006): 2790–95. http://dx.doi.org/10.1166/jnn.2006.414.

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A polyelectrolyte complex (PEC) micelle-based antisense oligodeoxynucleotide (ODN) delivery system was designed to overcome intrinsic limitations of cationic lipid-mediated gene transfer. Cationic lipid (Lipofectamine™, LF) and ODN conjugated poly(ethylene glycol) (PEG) were ionically complexed to form self-assembled spherical PEC micelles. They have a distinctive structural feature: a charge-neutralized core surrounded by highly flexible PEG corona. The PEC micelles could be visualized as a nano-sized sphere by atomic force microscopy (AFM). The DNA/LF PEC micelles exhibited far improved tran
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19

Medhi, Partha Pratim, Shashank Bansal, Faridha Jane Momin, and Ghritashee Bora. "Radiotherapy as a Cure for Covid-19 Pneumonia: Is this a Possibility?" Asian Pacific Journal of Cancer Care 5, S1 (2020): 157–59. http://dx.doi.org/10.31557/apjcc.2020.5.s1.157-159.

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The ongoing pandemic of COVID-19 caused by the Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV-2) has affected the healthcare system worldwide to a great extent. Millions of people have succumbed to the disease which might vary from mild febrile illness to severe Acute Lung Injury ultimately resulting in ARDS (Acute Respiratory Distress Syndrome). The mechanism of lung pathology due to SARS CoV-2 infection though unclear, is thought to be due to an imbalance in the inflammatory cascade; leading to a condition called Chemokine Release Syndrome. Low dose Radiotherapy which was histori
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20

Deng, Mingzhenlong, Chuang Zhang, Wanli Yan, Lei Chen, Bin He, and Yan Li. "Development of Fluorescence-Based Assays for Key Viral Proteins in the SARS-CoV-2 Infection Process and Lifecycle." International Journal of Molecular Sciences 25, no. 5 (2024): 2850. http://dx.doi.org/10.3390/ijms25052850.

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Since the appearance of SARS-CoV-2 in 2019, the ensuing COVID-19 (Corona Virus Disease 2019) pandemic has posed a significant threat to the global public health system, human health, life, and economic well-being. Researchers worldwide have devoted considerable efforts to curb its spread and development. The latest studies have identified five viral proteins, spike protein (Spike), viral main protease (3CLpro), papain-like protease (PLpro), RNA-dependent RNA polymerase (RdRp), and viral helicase (Helicase), which play crucial roles in the invasion of SARS-CoV-2 into the human body and its life
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21

Agarwal, Reita N., Hersheth Aggarwal, Ashmit Verma, and Manish K. Tripathi. "A Case Report of a Patient on Therapeutic Warfarin Who Died of COVID-19 Infection with a Sudden Rise in D-Dimer." Biomedicines 9, no. 10 (2021): 1382. http://dx.doi.org/10.3390/biomedicines9101382.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has disrupted social and economic life globally. The global pandemic COVID-19 caused by this novel SARS-CoV-2 shows variable clinical manifestations, complicated further by cytokine storm, co-infections, and coagulopathy, leading to severe cases and death. Thrombotic complications arise due to complex and unique interplay between coronaviruses and host cells, inflammatory response, and the coagulation system. Heparin and derivatives are World Health Organization (WHO) recommended anticoagulants for moderate and severe Coron
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22

Perryman, Michael, and Konstantin Zioutas. "Gaia, Fundamental Physics, and Dark Matter." Symmetry 14, no. 4 (2022): 721. http://dx.doi.org/10.3390/sym14040721.

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The Gaia space astrometry mission is measuring accurate distances and space motions of more than two billion stars throughout our galaxy and beyond. This is a first look at how Gaia is contributing to fundamental physics, and in particular to our understanding of dark matter, for which a few examples are given from the current literature. One of our goals is to illustrate how deep and often surprising insight into very diverse areas of fundamental physics can be extracted from this new and enormous high-accuracy stellar data set. In this spirit, we finish by suggesting a search for a connectio
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23

Sajinadiyasa, I. Gede Ketut, Ketut Suega, and Nova Andari K. "Correlations between level of vitamin D serum and disease severity COVID-19." International Journal of Advances in Medicine 11, no. 5 (2024): 445–48. http://dx.doi.org/10.18203/2349-3933.ijam20242306.

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Background: Corona virus disease (COVID-19) Was a respiratory disease. Severity of the disease was related to inflammation process. SCAP scoring system can be used to asses COVID-19 severity. Asses the severity of the disease is an important thing to determine the management. Vitamin D is shown to have anti-inflammatory effect. Vitamin D can downregulate cytokines storm and also induce innate immune activity. Here we want to know about the correlation between level of vitamin D and disease severity of COVID-19. Methods: Cross sectional study was observed 68 patient COVID-19 in Prof. Dr. I. G.
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24

Javad Mirza-Aghazadeh, Ali Sadaghianifar, Morad Ali Zareipour, Mohammad Mirza-Aghazadeh-Attari, and Jila Nagavi Kalejahi. "Social Mobilization in the Wake of Coronavirus Disease-19: A Brief Report of a Planned Approach to Community Health in Iran." Open Access Macedonian Journal of Medical Sciences 8, T1 (2020): 433–35. http://dx.doi.org/10.3889/oamjms.2020.5467.

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BACKGROUND: Several plans have been taken by health system to deal with COVID-19. The rapid spread of the virus and the special care that critical patients need put a major pressure on the healthcare system, which may not be able to compensate for its dimensions in various aspects. Therefore, the participation and cooperation of the society in the form of mobilizing the society with the health system will be effective in controlling and preventing this disease.&#x0D; AIM: The overall purpose of this study is to design a community mobilization framework based on the PATCH Model to prevent the s
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25

Bielousova, Natalyа, and Olha Skorostetska. "MODERN REALITIES OF THE TOURISM MARKET OF UKRAINE DURING THE CORONAVIRUS PERIOD: CHALLENGES AND PRACTICAL SOLUTIONS." GEOGRAPHY AND TOURISM, no. 57 (2020): 3–8. http://dx.doi.org/10.17721/2308-135x.2020.57.3-8.

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Purpose. To consider the problems of the tourism market in modern conditions, the crown of the viral period, with an emphasis on adapting the mechanism of tourist services, restructuring consciousness and looking for ways to optimize the implementation of new approaches in the practical work of travel agencies and higher educational institutions that train specialists in the tourism industry. Methodology. Analytical, statistical, comparative-geographical and synthetic methods were used. Results. The main conceptual issues on the problems of the existence of the tourist sphere of Ukraine during
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26

Ellersgaard, Christoph Houman, and Anton Grau Larsen. "Hvad skal en magtudredning ved afslutningen på historiens afslutning svare på?" Økonomi & Politik 95, no. 3-4 (2023): 5–15. http://dx.doi.org/10.7146/okonomi-og-politik.v95i3-4.135532.

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Siden Folketinget i slutningen af sidste år vedtog at gennemføre en ”opdatering af magtudredningen”, har vores verdensbillede allerede forandret sig. Dengang stod vi stadig overfor en kommende corona-nedlukning. Magtkritik handlede i høj grad om diskussionerne om begrænsningerne i den personlige frihed i det epidemiramte samfund. Siden da er Coronaen – i hvert fald for entid – lykkelig glemt, mens krigen i Ukraine, energiforsyning, inflation og – lidt mere lokalt – efterretningstjenester og minksager sætter spørgsmålstegn ved relationen mellem politikere, embedsmænd og offentlighed. De store,
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Taniya Katakwar, Heena Keshwani, Gargi Nimbulkar, Kumar Gaurav Chhabra, and Amit Reche. "Alternative Medicine for Fight against Covid-19/Coronavirus and “Alternative” Treatments." International Journal of Research in Pharmaceutical Sciences 11, SPL1 (2021): 1599–604. http://dx.doi.org/10.26452/ijrps.v11ispl1.3796.

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The most recent severe acute respiratory condition corona infection outburst has overwhelmed an ill-equipped nature among a festival season. It was first appeared on December 1, 2019, Wuhan (China) and recognized as a coronavirus and has spread worldwide. The manifestations are fever, discomfort and cough which resolve in a couple of days yet may advance to an extreme in most of the cases, but if any comorbidity exists in the form of diabetes, hypertension or any other debilitating systemic disease, then it can lead to grave prognosis. It spread mainly from one person to another through air dr
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28

Pogorletskiy, A. I., and F. Söllner. "Pandemics and Tax Innovations: What can we Learn from History?" Journal of Tax Reform 6, no. 3 (2020): 270–97. http://dx.doi.org/10.15826/jtr.2020.6.3.086.

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In this article, we shall see how pandemics of deadly diseases have changed tax systems over the past two millennia, each time leading to the emergence of new forms of taxation and tax administration. The purpose of the article is to prove that pandemics and the most notable innovations in tax policy are closely interrelated and that the consequences of the largest pandemics in the history of mankind are new approaches to the organization of national tax systems as well as the formation of interstate tax regulation. The lessons from history can be applied to the current corona crisis and may h
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29

Jyothsna, S., and D. Sammaiah. "Correlation of Trace Elemental Content in Selected Anti-Viral Medicinal Plants as Source of Active Molecules Used Against COVID-19 by ED-XRF Technique." ECS Transactions 107, no. 1 (2022): 577–84. http://dx.doi.org/10.1149/10701.0577ecst.

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Coronavirus is a positive sense RNA and has an envelope and has spread and effected globally leading to an increase in death tools. Currently, there is no effective drug for treatment and prevention of this disease. In this scenario, the only way to prevent the disease is the following certain safety guidelines and to boost up the immune system of body. Trace elements are essential for cellular process, growth, development, and boost up immune system. According to the previous studies, COVID-19 patients serum diagnostics tests illustrated that decreasing or increasing some elements in COVID-19
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30

Steckelings, U. Muscha, and Colin Sumners. "Correcting the imbalanced protective RAS in COVID-19 with angiotensin AT2-receptor agonists." Clinical Science 134, no. 22 (2020): 2987–3006. http://dx.doi.org/10.1042/cs20200922.

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Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is responsible for the global corona virus disease 2019 (COVID-19) pandemic enters host cells via a mechanism that includes binding to angiotensin converting enzyme (ACE) 2 (ACE2). Membrane-bound ACE2 is depleted as a result of this entry mechanism. The consequence is that the protective renin–angiotensin system (RAS), of which ACE2 is an essential component, is compromised through lack of production of the protective peptides angiotensin-(1-7) and angiotensin-(1-9), and therefore decreased stimulation of Mas (recep
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31

Mohylova, Maryna. "ECONOMIC CRISIS AS A FACTOR OF THE M&A MARKET IN JUSTIFICATION OF ANTI-CRISIS MANAGEMENT." Economic scope, no. 197 (February 11, 2025): 193–98. https://doi.org/10.30838/ep.197.193-198.

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The relevance of the research topic is due to the need to find directions for the development of companies in times of crisis and, accordingly, to form a substantiated system of anti-crisis management based on the diagnosis of all factors of business functioning. The strategy of mergers and acquisitions is considered as an alternative development strategy. The importance of diagnostics of the mergers and acquisitions market is proven in substantiating the company's development strategy by consolidating it with other enterprises or acquiring their shares. The purpose of the article is to substa
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32

Andreev, A. M., A. I. Tadzhibaev, A. Sh Azizov, et al. "Ensuring the reliability of turbogenerators on the basis of the control of discharge processes in the stator winding insulation." Safety and Reliability of Power Industry 15, no. 3 (2022): 199–204. http://dx.doi.org/10.24223/1999-5555-2022-15-3-199-204.

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Issues related to the reliability of the electrical insulation system of high-load powerful turbogenerators with indirect gas cooling are considered and analyzed. The mechanisms of aging of the main components (main insulation, slot filling elements) of the insulation system under operating conditions exposed to electrical and thermal fields, and mechanical forces are studied. Modern ideas about the mechanisms of aging of main insulation and slot filling elements under the action of internal and external impacts (slot and spark discharges) are analyzed. The degradation of insulating materials
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33

Amjad, Aneela, Sidra Manzoor, Syeda Zahra Wasti, et al. "Comparison of Vitamin D, Interleukin-6, And Interleukin-8 Levels in Covid Positive patients With or Without Cytokines Storm." Pakistan Journal of Medical and Health Sciences 16, no. 6 (2022): 192–93. http://dx.doi.org/10.53350/pjmhs22166192.

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Background: Currently world is within the clutches of the coronavirus disease (COVID-19) , caused by the SARS-CoV-2 virus, COVID-19 virus has evolved to human-to-human spread . COVID-19 infection can cause fever, fatigue, dry cough, severe pneumonia, respiratory distress syndrome and in some instances death. Release of cytokine is the main process by which COVID-19 affects human system. High level of chemokines and pro-inflammatory cytokines has been observed among the patients with COVID-19. Methodology: 100 COVID-19 positive patients with cytokine storm and100 COVID-19 positive patients with
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Wu, Ningbo, Yiting Li, and Lu Luo. "2022 Looking Back at COVID-19 and Stem Cell Therapy." Theoretical and Natural Science 4, no. 1 (2023): 72–77. http://dx.doi.org/10.54254/2753-8818/4/20220513.

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The global epidemic of Corona Virus Disease 2019 (COVID-19) has been raging since its outbreak in 2019, placing enormous strain on healthcare systems all over the world. The best course of action is to prevent COVID-19 in the future, despite the fact that its virological characteristics and pathogenesis have been largely understood. And all current treatment options probably include two types: one is active immunization and the other is passive immunization. Among them, passive immunity includes supportive therapy as well as neutralizing antibodies, and small molecule drugs and other treatment
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Odia, Yazmin, Ashley Love Sumrall, Timothy Francis Cloughesy, et al. "Single agent activity of ONC201 in non-midline H3 K27M-mutant diffuse gliomas." Journal of Clinical Oncology 39, no. 15_suppl (2021): e14037-e14037. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e14037.

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e14037 Background: H3 K27M-mutant diffuse midline glioma is an invariably lethal form of brain cancer that disproportionately affects children and young adults and has no effective treatment following front-line radiation. The initial disease definition in the 2016 WHO Classification of Tumors of the Central Nervous System regarded the H3 K27M mutation as pathognomonic, though the definition was updated in 2018 restricting the diagnosis to histologically diffuse gliomas that involve midline CNS structures (cIMPACT-NOW update 2). ONC201 is an investigational anti-cancer small molecule, DRD2 ant
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Odia, Yazmin, Ashley Sumrall, Timothy Cloughesy, et al. "CTNI-27. SINGLE AGENT ACTIVITY OF ONC201 IN NON-MIDLINE H3 K27M-MUTANT DIFFUSE GLIOMAS." Neuro-Oncology 23, Supplement_6 (2021): vi65. http://dx.doi.org/10.1093/neuonc/noab196.252.

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Abstract BACKGROUND H3 K27M-mutant diffuse midline glioma is an invariably lethal form of brain cancer that disproportionately affects children and young adults and has no effective treatment following front-line radiation. The initial disease definition in the 2016 WHO Classification of Tumors of the Central Nervous System regarded the H3 K27M mutation as pathognomonic, though the definition was updated in 2018 restricting the diagnosis to histologically diffuse gliomas that involve midline CNS structures (cIMPACT-NOW update 2). ONC201 is an investigational anti- cancer small molecule, DRD2 a
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37

Hussein, Mouraya, Zaria Andrade dos Ramos, Ben Berkhout, and Elena Herrera-Carrillo. "In Silico Prediction and Selection of Target Sequences in the SARS-CoV-2 RNA Genome for an Antiviral Attack." Viruses 14, no. 2 (2022): 385. http://dx.doi.org/10.3390/v14020385.

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The SARS-CoV-2 pandemic has urged the development of protective vaccines and the search for specific antiviral drugs. The modern molecular biology tools provides alternative methods, such as CRISPR-Cas and RNA interference, that can be adapted as antiviral approaches, and contribute to this search. The unique CRISPR-Cas13d system, with the small crRNA guide molecule, mediates a sequence-specific attack on RNA, and can be developed as an anti-coronavirus strategy. We analyzed the SARS-CoV-2 genome to localize the hypothetically best crRNA-annealing sites of 23 nucleotides based on our extensive
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38

ISI-SENAI-CIMATEC Group and Development and Innovation Laboratory of Butantan Institute. "Therapies Against COVID-19: a Running to a Treatment." JOURNAL OF BIOENGINEERING AND TECHNOLOGY APPLIED TO HEALTH 3, no. 2 (2020): 184–248. http://dx.doi.org/10.34178/jbth.v3i2.125.

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There is no specific drug or therapy against COVID-19. Since the beginning of the pandemic, scientists are running to discover a drug or therapy that can treat the disease. What we found until now are a combined drug and therapies that can mitigate the effects of the disease in the human body and how to manage the patient better. In this article, we tried to join the new discoveries and presented the drugs and therapies and their mechanisms to combat the SARS-CoV-2. We showed the immunomodulators, parasiticides, antiviral drugs (focused on Remdesivir), antimalarial drugs, anti-cytokine drugs f
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39

Zuckerstätter, Sepp, Lukas Kafenda, Mattias Muckenhuber, and Reinhold Russinger. "Austria: Policies dealing with the inflation crisis." Wirtschaft und Gesellschaft 48, no. 4 (2023): 578–98. http://dx.doi.org/10.59288/wug484.167.

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Inflation in Austria started to rise from mid-2021 during recovery from the Corona crisis. The Russian invasion in Ukraine and the heavy increases in energy prices made things worse and brought inflation to over 10%. The government did not enter into direct formal negotiations with social partners but subsequent anti-inflation packages met many demands made by the social partners. The attempt to influence wage negotiations via a tax exemption for one-off payments failed as they were not widely used in collective agreements. One-off payments are not suitable to compensate for permanent real wag
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TÜRKDÖNMEZ, Elif. "NSAIDs medication for headache as the presenting symptom with migraine and COVID‐19." Journal of Experimental and Clinical Medicine 38, no. 4 (2021): 645–48. http://dx.doi.org/10.52142/omujecm.38.4.43.

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Headache is one of the most prevalent disorders of the nervous system. Headache is also the most common symptom of a variety of diseases, 4Department of XXX, Faculty of XXX, City, Country including migraine, COVID-19. International Classification of Headache Disorders (ICHD) lists over a thousand different types of headaches. Migraine is a widely known type of primary headache. Much research supports that the enhancement in migraine intensity related to chronic migraine such as neurogenic neuroinflammation, possibly leading to increased cytokine expression via activation of protein kinases in
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41

Alveena Sadiq, Aisha Sana, Fatima Qamar, Halima Sadia, and Saman Shahab. "Review Article on the Role of Vitamin C in the Prevention of COVID-19 or Viral Infection." International Journal of Trends in Health Sciences 1, no. 1 (2023): 11–16. http://dx.doi.org/10.61980/3049-7620/2023/1/6.

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The corona virus disease COVID-19 has affected almost 2.5 million people and around 192 countries worldwide affected from this virus and day by day the number of death figure increases. The pathogen, initially isolated from a Chinese patient, was identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It primarily impacts the lungs, leading to pneumonia and acute respiratory distress syndrome. The initial symptoms are like flu i.e. fever flu and cough but by the time it converted into degradation of epithelial cells of lungs and huge release of cytokines named as cytokine s
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Ogunyemi, Oludare M., Gideon A. Gyebi, Abdo A. Elfiky, et al. "Alkaloids and flavonoids from African phytochemicals as potential inhibitors of SARS-Cov-2 RNA-dependent RNA polymerase: an in silico perspective." Antiviral Chemistry and Chemotherapy 28 (January 2020): 204020662098407. http://dx.doi.org/10.1177/2040206620984076.

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Corona Virus Disease 2019 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Exploiting the potentials of phytocompounds is an integral component of the international response to this pandemic. In this study, a virtual screening through molecular docking analysis was used to screen a total of 226 bioactive compounds from African herbs and medicinal plants for direct interactions with SARS-CoV-2 RNA-dependent RNA polymerase (RdRp). From these, 36 phytocompounds with binding affinities higher than the approved reference drugs (remdesivir and sobosivi
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43

Irfandi, Rizal, Muhammad Ilham, Erwing, et al. "Review on Curcumin Compounds in Turmeric Plants for the Treatment of COVID-19." International Journal of Design & Nature and Ecodynamics 17, no. 6 (2022): 957–65. http://dx.doi.org/10.18280/ijdne.170618.

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Coronavirus Disease (COVID-19) is an infectious disease that has a high fatality rate and is spreading quickly throughout the world. The WHO claims that SARS-CoV-2, a brand-new coronavirus strain, is to blame for this outbreak (Severe Acute Respiratory Syndrome Corona Virus-2) and that COVID-19 must be treated with both conventional medical therapy and a combination of modern medicine. The technique of this study, a review of the literature, focused on numerous investigations looking at the potential of curcumin molecules from turmeric to cure the COVID-19 disease. Primary data for scientific
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Sarmento, Bruno, Cecília Cristelo, Juliana Viegas, et al. "ORAL DELIVERY OF BUDESONIDE-LOADED NANOPARTICLES WITH OXIDATIVE-RESPONSIVE DEPEGYLATION ENHANCES INFLAMMATION RESOLUTION IN COLITIS-INDUCED MICE." Inflammatory Bowel Diseases 31, Supplement_1 (2025): S5. https://doi.org/10.1093/ibd/izae282.013.

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Abstract The rising global prevalence of Inflammatory Bowel Disease (IBD) and its significant socio-economic impact highlight the urgent need to develop innovative solutions to overcome the poor targeting efficiency and short retention time faced by current treatments. Hence, the aim of this work was to use an advanced oxidative-responsive nanosystem to selectively target and accumulate at inflamed tissues for oral administration of budesonide, a corticosteroid used to treat intestinal inflammation. For this system, muco-diffusive poly(lactic-co-glycolic) acid (PLGA) nanoparticles (NPs) were f
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45

Pramanik, Parthiba, and Purushottam Pramanik. "Diabetes mellitus augments the complications of patients with COVID-19: a review." International Journal of Research in Medical Sciences 8, no. 7 (2020): 2716. http://dx.doi.org/10.18203/2320-6012.ijrms20202925.

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Corona virus disease 2019 (COVID-19) is current pandemic infection caused by RNA virus named severe acute respiratory syndrome coronavirus-2 (SARS Cov-2). The lungs are the organs most affected by COVID-19 and people were died due to severe acute respiratory s syndrome, pneumonia and multi-organs failure. Fatality rate was more, those who suffer in chronic diseases including diabetes mellitus (DM). As COVID-19 pandemic is accelerating , it is important to understand the molecular mechanism through which DM increases the severity related to COVID-19 to able to design more appropriate therapy. T
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46

Nagula, Mounish R., and Abhijit S. Joshi. "COVID-19 vaccine: Culprit or innocent bystander in a rare adverse gastro-intestinal surgical event? A case report with review of literature." Journal of Family Medicine and Primary Care 13, no. 5 (2024): 2152–56. http://dx.doi.org/10.4103/jfmpc.jfmpc_1006_23.

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ABSTRACT Corona virus disease (COVID-19) initially appeared to be an exclusively respiratory ailment. While that is true in a vast majority of the cases, its evolution and later evidence have shown that it can afflict virtually any organ system in the human body after first gaining entry through the respiratory tract. The COVID-19 vaccines were one of the turning points in the campaign to control the COVID-19 pandemic. However, after their extensive use all over the world, it has emerged that they can cause some dangerous collateral damage. We, herein, report the case of a 58-year-old woman wh
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47

Gopalaswamy, Radha, and Selvakumar Subbian. "Corticosteroids for COVID-19 Therapy: Potential Implications on Tuberculosis." International Journal of Molecular Sciences 22, no. 7 (2021): 3773. http://dx.doi.org/10.3390/ijms22073773.

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On 11 March 2020, the World Health Organization announced the Corona Virus Disease-2019 (COVID-19) as a global pandemic, which originated in China. At the host level, COVID-19, caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), affects the respiratory system, with the clinical symptoms ranging from mild to severe or critical illness that often requires hospitalization and oxygen support. There is no specific therapy for COVID-19, as is the case for any common viral disease except drugs to reduce the viral load and alleviate the inflammatory symptoms. Tuberculosis (TB),
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48

Ghidan, Alaa Yousef, Fatima Yousef Ghethan, Mohammad Alghanmi, et al. "Global impact and clinical management of severe respiratory syndrome coronovirus-2 (COVID-19)." Journal of Applied and Advanced Research 5 (October 31, 2020): 11. http://dx.doi.org/10.21839/jaar.2020.v5.342.

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Coronaviruses are enveloped non-segmented positive-sense RNA viruses belonging to the family Coronaviridae and the order Nidovirales and broadly distributed in humans and other mammals. The recommendations for the management of COVID-19 are mentioned in a lot of Updated Literature such as in The "L. Spallanzani" National Institute for the Infectious Diseases. These recommendations are considered as expert's opinions, which may be modified according to newly produced literature data. In addition, Chloroquine and its derivative, hydroxychloroquine, have a long history as safe and inexpensive dru
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49

Kamenova, Katya, Lyubomira Radeva, Spiro Konstantinov, Petar D. Petrov та Krassimira Yoncheva. "Copolymeric Micelles of Poly(ε-caprolactone) and Poly(methacrylic acid) as Carriers for the Oral Delivery of Resveratrol". Polymers 15, № 18 (2023): 3769. http://dx.doi.org/10.3390/polym15183769.

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In this study, we report the development of a micellar system based on a poly(methacrylic acid)-b-poly(ε-caprolactone)-b-poly(methacrylic acid) triblock copolymer (PMAA16-b-PCL35-b-PMAA16) for the oral delivery of resveratrol. The micellar nanocarriers were designed to comprise a PCL core for solubilizing the poorly water-soluble drug and a hydrated PMAA corona with bioadhesive properties for providing better contact with the gastrointestinal mucosa. The micelles were first formed in an aqueous media via the solvent evaporation method and then loaded with resveratrol (72% encapsulation efficie
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KHODZHAIAN, A.А., and T.V. МELNIKOVA. "Interest rate as a monetary policy instrument in the context of the crisis and post–crisis period." Market Relations Development in Ukraine №4(251)2022 117 (August 3, 2022): 5–14. https://doi.org/10.5281/zenodo.6956925.

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The subject of research &ndash; the monetary policy of the state in a crisis. The purpose of this article is to analyze and systematize the use of interest rates as a key instrument of monetary policy in the crisis and post&ndash;crisis period. Research methodology &ndash; methods of abstraction and generalization (in the systematization of measures to adjust the NBU key policy rate of in 2020&ndash;2021); analysis and synthesis (in substantiating the stages of implementation of the NBU&rsquo;s monetary policy in the context of the corona crisis). Results &ndash; It is substantiated that in th
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